Abstract: A rubber composition usable for the manufacture of tires, based on at least one diene elastomer, a reinforcing inorganic filler and a coupling agent providing the bond between the inorganic filler and the elastomer, wherein said inorganic filler comprises a silicon carbide having the following characteristics: (a) a BET specific surface area of between 20 and 200 m2/g; (b) an average particle size (by mass), dW, of between 10 and 350 nm. Tires or semi-finished products for tires such as treads comprising said rubber composition.

Abstract: Disclosed are flame retardant compositions comprised of (a) brominated anionic styrenic polymer, and (b) at least one polybrominated alpha-omega diphenylalkane having a total of at least 6 bromine atoms directly bonded to the phenyl rings and in the range of 1 to 6 carbon atoms in the alkylene group disposed between the phenyl groups, and specified flame retarded polymer compositions with which have been blended (a) and (b) individually or in combination.

Abstract: The invention relates to an adhesive composition comprising (i) one or more styrenic block copolymers, (ii) a tackifier resin, and (iii) one or more plasticizers, wherein the or one of the styrenic block copolymers is of the general formulae A-C-A, ??(1) or (A-C)n-X, ??(2) wherein each A independently is a polymer block of an aromatic vinyl compound, and C is a mixed polymer block (B/I) of butadiene (B) and isoprene (I) in a weight ratio B:I in the range of 30:70 to 70:30, and said polymer block C has a glass transition temperature (Tg) of at most ?50° C. (determined according to ASTM E-1356-98), n is an integer equal to or greater than 2, and X is the residue of a coupling agent, and wherein the tackifier resin has an aromaticity (in relative percentage of aromatic protons as determined by H-NMR) in the range of from 3 to 18%.

Abstract: A polyamide resin composition for part of an engine cooling water system contains 100 parts by weight of a polyamide resin made of(A) from 50 to 98% by weight of nylon 66, (B) from 1 to 30% by weight of an aromatic polyamide resin, and (C) from 1 to 20% by weight of nylon 12; and (D) from 5 to 150 parts by weight of an inorganic filler, with the total content of nylon 66, the aromatic polyamide resin and nylon 12 being 100% by weight.

Abstract: A fluoroelastomer composition, which comprises 100 parts by weight of vinylidene fluoride-perfluoro(methyl vinyl ether)-tetrafluoroethylene terpolymer or vinylidene fluoride-hexafluoropropene copolymer, and 10–50 parts by weight of liquid fluoroelastomer having a viscosity of 500 to 3,000 cps at 100° C., can be made cross-linkable or vulcanizable fluoroelastomer composition upon further addition of 0.5 to 5 parts by weight of an organic peroxide and 0.5 to 10 parts by weight of a polyfunctional unsaturated compound or further addition of 0.5 to 10 parts by weight of a polyol-based vulcanizing agent thereto. The fluoroelastomer composition can give a cross-linked or vulcanized product having a hardness (Durometer A) of not more than 50 and distinguished processability and compression set resistance characteristics.

Abstract: A method of preparing a dispersion which includes the step of contacting a first phase, a first material immiscible therewith, a first polymeric material and a second polymeric material wherein: (a) (i) said first polymeric material has a repeat unit of the formula (I), wherein A and B are the same or different, are selected from optionally-substituted aromatic and thereoaromatic groups and at least one comprises a relatively polar atom or group and R1 and R2 independently comprise relatively non-polar atoms or groups; (ii) said first polymeric material is prepared or preparable by providing a compound of general formula (I), wherein A, B, R1 and R2 are as described above, in an aqueous solvent and causing the groups C?C in said compound to react with one another to form said first polymeric material; (b) said second polymeric material includes a functional group which is able to react with said first polymeric material so that covalent bonds are formed between said first and second polymeric materials; (c) t

Abstract: Method for preparation of an aqueous emulsion from a curable silicone composition consisting of (A) an organopolysiloxane having at least two silicon-bonded hydroxyl groups, (B) an organohydrogensiloxane, and (C) a curing catalyst, said method being characterized by (i) continuously supplying component (A), component (B) and component (C), or a mixture of components (A) and (B) and component (C) through individual inlet ports into a continuous mixer and mixing said components at a temperature not exceeding 10° C., (ii) continuously supplying the obtained mixture and (D) an aqueous solution of a surface-active agent to an emulsifier, and emulsifying the components at a temperature not exceeding 20° C. An apparatus for the preparation of an aqueous emulsion of a curable silicone composition comprising of a continuous mixer for mixing components (A) through (C), a distribution unit connected to the lower part of the mixer, and an emulsifier.

Abstract: Polyisocyanurate systems, pultrusion of those systems to produce reinforced polyisocyanurate matrix composites, and to composites produced thereby. The polyisocyanurate systems include a polyol component, an optional chain extender, and an isocyanate. The polyisocyanurate systems have extended initiation times of about 5 minutes to about 30 minutes at room temperature, and can be snap cured.

Abstract: Golf equipment having improved cut and shear resistance that includes a polyurea-based composition or polyurethane-based composition, preferably saturated and/or water resistant, formed of a prepolymer, a functionalized block copolymer, and optionally further cured or chain extended with a curing agent, where the prepolymer is incorporated at the terminal end of the functionalized block copolymer.

Abstract: An underfill material is presented that may be used between an electrical component and a substrate. The underfill material may be a cured epoxy resin composition comprising a liquid or semisolid epoxy resin and a polyfunctional anhydride polymer and/or oligomer curing agent. The use of anhydride polymers and/or oligomers decrease the volatilization of the composition, thereby reducing the porosity of the underfill material. By changing substituents of the anhydride polymer and/or oligomer, the underfill material may be designed to modify viscosity, decrease moisture adsorption, volatilization and modulus, improve mechanical properties, and enhance adhesion.

Abstract: Improved thermoplastic polymer blend compositions comprising an isotactic polypropylene component and an alpha-olefin and propylene copolymer component, said copolymer comprising crystallizable alpha-olefin sequences. In a preferred embodiment, improved thermoplastic polymer blends are provided comprising from about 35% to about 85% isotactic polypropylene and from about 30% to about 70% of an ethylene and propylene copolymer, wherein said copolymer comprises isotactically crystallizable propylene sequences and is predominately propylene. The resultant blends manifest unexpected compatibility characteristics, increased tensile strength, and improved process characteristics, e.g., a single melting point.

Abstract: Disclosed are a method for producing a modified conjugated diene polymer improved in quality stability, more enhanced in low heat buildup and reinforcing ability when used in a rubber composition, excellent in wear resistance, mechanical characteristics and processability, and improved in cold flow; and a rubber composition using the same. The method includes a step of modifying an active end of an active end-containing conjugated diene polymer having a cis-1,4-bond content of 75% or more with an alkoxysilane compound containing at least one functional group selected from the group consisting of (a) an epoxy group, (b) an isocyanate group and (c) a carboxyl group, and a step of adding a condensation accelerator to conduct condensation reaction of the alkoxysilane compound (residue) in an aqueous solution having a pH of 9 to 14 and a temperature of 85 to 180° C.

Abstract: A sulfur curing system EPDM composition in which one or more types of vulcanization accelerators selected from thiazole type and sulfenamide type accelerators and one or more types of vulcanization accelerators selected from dithiocarbamate type and thiuram type accelerators are combined together so as to be compounded into the EPDM composition as a vulcanization accelerator, and an automotive brake system rubber component made of the EPDM composition.

Abstract: Use is made, for selectively hydrogenating the olefinic double bonds of block copolymers, at least one block of which comprises olefinic double bonds, using a catalyst based on a metal from Group VIII in a medium comprising an organic solvent for the copolymer and an ionic liquid as solvent for the catalyst, of a water-immiscible ionic liquid, preferably an ionic liquid for which the anion is the hexafluorophosphate anion and the cation is the 1-butyl-3-methylimidazolium (bmim+) or 1-ethyl-3-methylimidazolium (emim+) cation. Applied to poly(styrene)-b-poly(butadiene)-b-poly(methyl methacrylate) block copolymers, the poly(butadiene) block of which predominantly possesses a 1,4-microstructure, this process results in copolymers for which the degree of hydrogenation is at least equal to 50% and which exhibit a melting point of greater than 30 °C.

Abstract: A composition comprising at least one silane possessing an unsaturated organic function; at least two free radical initiators, and a process for producing silane-crosslinked thermoplastic polymers comprising providing a cross-linkable compound; at least one thermoplastic polymer; and, reacting the crosslinkable compound under reactive mechanical-working conditions and exposing the crosslinkable compound to moisture to provide crosslinked thermoplastic polymers.

Abstract: An alkenyl- or crosslinkable silyl-terminated vinyl polymer is provided. Such a functional group is introduced into its terminus at a high ratio, not via sulfur atoms. Those polymers can be prepared by polymerizing a vinyl monomer for obtaining a halogen-terminated vinyl polymer, and then substituting an oxy anion or carbanion having such a functional group for the terminal halogen of said polymer.

Abstract: There is disclosed a novel mixture of polyhydroxy phenolic curing agents, such as novolac resins blended with a mixture of mono, bis and tris hydroxyaryl phosphine oxides for co-curing epoxy resins and imparting flame resistance thereto. A preferred composition includes a mixture of monohydroxyaryl, bishydroxyaryl and trishydroxyaryl phosphine oxide and a benzoguanamine/phenol/formaldehyde terpolymer which is used along with an epoxy resin to produce flame-resistant printed wiring boards without the use of halogens.

Abstract: A method for preparing a cyclic olefin polymer is described. The method includes polymerizing cyclic olefin monomers or a cyclic olefin monomer with ethylene to prepare a cyclic olefin polymer solution; slowly adding a non-solvent drop wise to the cyclic olefin polymer solution to precipitate a cyclic olefin polymer; and filtering and drying the precipitated cyclic olefin polymer. In addition, the cyclic olefin polymer prepared using this method is described. According to the present invention, a spherical cyclic olefin polymer having a high bulk density can be easily separated from the cyclic olefin polymer solution by precipitation.

Abstract: A process for polymerizing polyethylene with chromium-based catalysts wherein one or more supported chromium-based catalysts is mixed with mineral oil to form a slurry and the slurry is then introduced into a polymerization reactor, especially a gas-phase polymerization reactor.

Abstract: The present invention relates to a solid catalyst component for the polymerization of olefins CH2?CHR in which R is hydrogen or a hydrocarbon radical with 1–12 carbon atoms, comprising Mg, Ti, halogen and an electron donor selected from succinates, said catalyst component being obtainable by a process comprising the following steps: (a) dissolving a halide of magnesium in a solvent system comprising an organic epoxy compound or an organic phosphorus compound and optionally an inert diluent to form a solution; (b) mixing the obtained solution with a titanium compound to form a mixture; (c) precipitating a solid from the mixture obtained in step (b) in the presence of a succinate and/or an auxiliary precipitant; (d) if a succinate is not used in step (c), contacting the solid obtained in (c) with a succinate, and (e) treating the solid obtained in (c) or (d) with a titanium compound optionally in the presence of an inert diluent.

Abstract: A process for polymerizing ethylene comprising contacting under polymerization condition ethylene and optionally one or more olefins with a catalyst system obtainable by contacting: a bis amido compound of formula (I) wherein Y is Si, Ge and Sn; X is hydrogen, halogen or an hydrocarbon radical; R1, R2, R3, R4, R5 and R6, are hydrocarbon radical; Q is a neutral Lewis base; and m is 0–2; one or more boron activating cocatalysts and one or more aluminum alkyls or alumoxanes.

Abstract: A modified particle obtained by a process containing contacting a Bi compound, a compound having an electron-withdrawing group and an active hydrogen and particle; and a catalyst component for addition polymerization containing the modified particle; a catalyst for addition polymerization prepared by a process containing contacting the modified particle (A) and a transition metal compound of Groups 3 to 11 or lantanide series (B); and a catalyst for addition polymerization prepared by a process containing contacting the modified particle (A) and a transition metal compound of Groups 3 to 11 or lantanide series (B) and an orbanoaluminum compound (C); and a process for producing an addition polymer with the catalyst.

Abstract: A method is provided for cationically polymerizing olefin monomer by using a novel coinitiator in the presence of water. More specifically, a method is provided for cationically polymerizing olefin monomer by using a novel coinitiator in an aqueous suspension or aqueous emulsion polymerization process.

Abstract: Polymerizable fluorinated ester compounds having formula (1) or (2) are novel wherein R1 is H, methyl or trifluoromethyl, R2 is a divalent hydrocarbon group, R3 is H or a monovalent hydrocarbon group, or R2 and R3, taken together, may form a ring, R4 is H, OH or a monovalent hydrocarbon group, and R5 is an acid labile group.

Abstract: Water-soluble copolymers based on olefinic sulfonic acids, olefinic dicarboxylic acids, vinyl amides and vinyl ethers and/or allyl ethers and/or bisacryl derivatives are described as well as processes for their production and the use of these copolymers as water retention agents, thickeners or anti-segregation agents for aqueous building material systems that contain hydraulic binding agents such as cement, lime, gypsum, anhydrite etc. or for clay suspensions preferably based on bentonite.

Abstract: The invention concerns a silicone composition crosslinkable into elastomer by hydrosilylation, in the presence of carbene-based metal catalysts. The invention aims at providing a composition of that type, stable over long periods at room temperature (one day to several months), without loss of its characteristic of being heat-curable by hydrosilylation and without generating secondary isomerization or coloring reactions. The invention is characterised in that the composition comprises: a polyorganovinylsiloxane(polydimethyl)(methylvinyl) siloxane; a polyorganohydrogenosiloxane; a platinum catalyst formed by a complex of formula C3 and optionally an acetylene crosslinking inhibitor, optionally a siliceous filler. The invention also concerns novel hydrosilylation catalysts of the metal complex type of formula C3 above.

Abstract: The present invention is directed to a method for applying to a substrate, in the form of a seal, a polysiloxane-containing coating, preferably a polysiloxane(amide-ureide) coating capable of inhibiting corrosion as well as the accumulation of ice. One embodiment of the present invention is directed to a polysiloxane(amide-ureide) that forms a durable, long lasting, anti-corrosive and anti-ice coating when applied to a substrate as a seal.

Abstract: A thermoplastic polyether polyurethane having high moisture vapor transmission, high melting point and static dissipative properties is disclosed. The thermoplastic polyether polyurethane is prepared by reacting a hydroxyl terminated polyether intermediate, an aromatic chain extender glycol, and a polyisocyanate. The polymers formed are useful for melt-spun fibers, fabric coatings for breathable garments, house wrap, roofing membranes, and other applications requiring high vapor transmission and high melting points.

Abstract: A polycarbonate resin with a polystyrene-converted weight average molecular weight (Mw) of 20,000 to 200,000 obtained by forming a carbonate bond from a dihydroxy compound represented by the general formula (1), a dihydroxy compound represented by the general formula (2) and bis(hydroxyphenyl) methane and a carbonic acid diester or phosgene, having higher stiffness and better balance of mechanical properties than conventional aromatic polycarbonate resin to be derived from 2,2-bis(4-hydroxyphenyl)propane.

Abstract: Disclosed is a fluorine compound having perfluorostyrene introduced at a terminal thereof, as represented in the following Formula 1, and a coating solution and an optical waveguide device using the same, characterized in that the introduction of perfluorostyrene results in a facile fabrication of thin films by a UV curing or a thermal curing, high thermal stability and chemical resistance, and low optical propagation loss and birefringence: Wherein Z is O or S; RF is an aliphatic or aromatic group; y is a natural number of 1–10; y? is an integer of 0–1; x is an integer of 0–200; and Wherein B is a single bond or selected from the group consisting of —CO—, —SO2—, —S— and —O—, and Hal is selected from the group consisting of F, Cl, Br and I.

Abstract: Polymers containing poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles are disclosed along with methods of fabricating medical articles comprising these polymers. The medical articles generally comprise an implantable substrate having a coating containing a poly(hydroxyalkanoate-co-ester amide).

Abstract: A glycolic acid copolymer comprising (a) 80 to less than 95% by mole of glycolic acid monomer units, (b) 5.0 to 20.0% by mole of non-glycolic, hydroxycarboxylic acid monomer units, and (c) 0 to 0.10% by mole of diglycolic acid monomer units, the non-glycolic, hydroxycarboxylic acid monomer units (b) constituting a plurality of segments each independently consisting of at least one monomer unit (b), wherein the segments have an average chain length of from 1.00 to 1.50 in terms of the average number of monomer unit or units (b), the total of the components (a), (b) and (c) being 100% by mole, the glycolic acid copolymer having a weight average molecular weight of 50,000 or more.

Abstract: The invention relates to novel polymers or oligomers containing at least sulfonite groups (P-(SO2)nX, X=1?(n=1), 2?(n=2) or 3?(n=3) valent metal cation or H+ or ammonium ion NR4+ wherein R=alkyl, aryl, H), which are obtained by completely or partially reducing polymers or oligomers containing at least SO2Y-groups (Y=F, Cl, Br, I, OR, NR2 (R=alkyl and/or aryl and/or H), N-imidazolyl, N-pyrazolyl) by means of suitable reducing agents in a suspension or in a solution form. The invention also relates to polymers and polymer(blend) membranes which are obtained by further reacting the obtained sulfinated polymers, especially by alkylation of the sulfinate groups with mono- di- or oligo functional electrophiles. The invention further relates to methods for producing the sulfinated polymers and for further reacting the sulfinated polymers with electrophiles by S-alkylation.

Abstract: Method of producing an article comprising providing a raw material in the form of a plurality of polymer elements, the polymer elements comprising an amorphous polymer; heating the materials to a temperature above a first predetermined temperature; and compacting the material whilst above the first predetermined temperature. The first predetermined temperature is the Tg of the polymer elements, the pressure is between 100 and 200 psi; and the temperature and pressure of compaction are sufficient to soften the outer portion of the polymer elements and to cause the polymer elements to bonds to each other without melting or softening of the inner portion of polymer elements. A product is produced having a structure which comprises cores of amorphous polymer that have not been softened or melted in the method, surrounded by a mass of softened and re-hardened material which bonds the cores together.

Abstract: Isolated protein complexes are provided comprising Tsg101 and HIV GAGp6. The protein complexes are useful in screening assays for selecting compounds effective in modulating the Tsg101-HIV GAGp6 interaction within the protein complexes.

Abstract: The invention relates to compounds having a binding affinity for both the ?v?3 receptor and a (neuro)peptide receptor, in particular the somatostatin receptor, which compound comprises a first peptide part comprising at least once the amino acid sequence Arg-Gly-Asp, and a second peptide part coupled thereto, optionally via a linker, which second peptide part is a (neuro)peptide.

Abstract: The present invention provides synthetic compounds, antibodies that recognize and bind to these compounds, polynucleotides that encode these compounds, and immune effector cells raised in response to presentation of these epitopes. The invention further provides methods for inducing an immune response and administering immunotherapy to a subject by delivering the compositions of the invention.

Abstract: The present invention relates to a method for preparing a peptide having a stable, internally constrained alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region and a method of stabilizing an alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region within a peptide structure. The resulting peptides and methods of using them are also disclosed.

Abstract: A cDNA sequence encoding the ?-subunit of human mast cell IgE surface receptor or an IgE binding fragment thereof.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Abstract: The crystal structure of the product, crystals of the MarR protein, a regulator of multiple antibiotic resistance in Escherichia coli, and methods of crystallization of the MarR protein are described.

Abstract: Nitrosylhemoglobin can be produced by introducing gaseous NO into an aqueous solution of hemoglobin. It has been demonstrated that nitrosylhemoglobin in aqueous solution can be converted to SNO-hemoglobin upon introduction of oxygen to the solution, as is postulated to occur in the lungs. Nitrosylhemoglobin can be used in methods to produce the physiological effects of NO, for example, to reduce vasoconstriction and to inhibit platelet aggregation.

Abstract: A hemoglobin solution packaged in a flexible oxygen-impermeable container system. The container system includes a multi-layer film having at least a product contact layer, an oxygen and moisture barrier layer and an exterior layer. The flexible container system further includes an interface port for filling the flexible container with the hemoglobin solution and delivering the hemoglobin solution. The hemoglobin solution comprises a substantially stroma and tetramer free, cross linked, pyridoxylated hemoglobin solution including preservatives such as ascorbic acid, glycine and dextrose.

Abstract: Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.

Abstract: Embodiments of the invention described herein relate to antibodies directed to the antigen monocyte chemo-attractant protein-1 (MCP-1) and uses of such antibodies. In particular, in accordance with some embodiments, there are provided fully human monoclonal antibodies directed to the antigen MCP-1. Nucelotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDRs), specifically from FR1 through FR4 or CDR1 through CDR3, are provided. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also provided.

Abstract: The invention concerns new secreted factors encoded by clones P00184_D11 (SEQ ID NO: 1), P00185_D11 (SEQ ID NO: 3), P00188_D12 (SEQ ID NO: 5), P00188_E01 (SEQ ID NO: 7), P00194_G01 (SEQ ID NO: 9), P00194_G05 (SEQ ID NO: 11), P00194_H10 (SEQ ID NO: 13), P00199_D08 (SEQ ID NO: 15), P00203_D04 (SEQ ID NO: 17), P00203_E06 (SEQ ID NO: 19), P00209_F06 (SEQ ID NO: 21), P00219_D02 (SEQ ID NO: 23), P00219_F06 (SEQ ID NO: 25), P00220_H05 (SEQ ID NO: 27), P00222_G03 (SEQ ID NO: 29), P00225_C01 (SEQ ID NO: 32), P00227_D11 (SEQ ID NO: 34), P00228_F03 (SEQ ID NO: 36), P00233_H08 (SEQ ID NO: 38), P00235_G08 (SEQ ID NO: 40), P00239_C11 (SEQ ID NO: 42), P00240_E05 (SEQ ID NO: 45), P00247_A04 (SEQ ID NO: 50), P00248_B04 (SEQ ID NO: 52), P00249_F09 (SEQ ID NO: 54), P00258_A10 (SEQ ID NO: 56), P00262_C10 (SEQ ID NO: 58), P00269_H08 (SEQ ID NO: 62), P00628_H02 (SEQ ID NO: 66), P00629_C08 (SEQ ID NO: 68), P00641_G11 (SEQ ID NO: 71), P00648_E12 (SEQ ID NO: 73), P00697_C03 (SEQ ID NO: 75), and other mammalian homologues and variants