Patents Issued in November 27, 2007
  • Patent number: 7301037
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: November 27, 2007
    Assignee: Genesoft, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Burli
  • Patent number: 7301038
    Abstract: A process for the preparation of alkylene oxide, which process involves passing a feed containing an organic hydroperoxide and alkene through a bank of at least two serially connected reactors containing epoxidation catalyst and withdrawing a product stream having alkylene oxide and an alcohol as reaction products, in which bank of reactors the temperature of the feed is controlled such that during operation the outlet temperature of the final reactor is at least 4° C. higher than the outlet temperature of the first reactor.
    Type: Grant
    Filed: May 3, 2002
    Date of Patent: November 27, 2007
    Assignee: Shell Oil Company
    Inventors: Johannes Petrus Van Der Linden, Ingmar Hubertus Josephina Ploemen, Augustinus Santen, Alexander Jan Van Der Veen
  • Patent number: 7301039
    Abstract: The invention comprises a process for the preparation and isolation of a non-amorphous cationic rhodium complex having the formula: [Rh(ligand)m(diolefin)]+X?, wherein the ligand is an enantiomerically enriched organic compound possessing one or two ligating phosphorus atoms.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: November 27, 2007
    Assignee: Dow Global Technologies Inc.
    Inventors: James Andrew Ramsden, Paul Henry Moran
  • Patent number: 7301040
    Abstract: Bidentate catalyst systems and the methods or forming such are described herein. The catalyst systems generally are compounds having the general formula: where R, R1, R2 and R3 are optional and independently selected from hydrogen, C1 to C20 alkyl groups or C6 to C20 aryl groups, A? and A? are independently selected from coordination groups, M is a Group 4 or 5 transition metal, X is selected from halogens, alkyl groups, aromatic groups or combinations thereof and n is less than 4.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: November 27, 2007
    Assignee: Fina Technology, Inc.
    Inventors: Abbas Razavi, Vladimir P. Marin, Margarito Lopez
  • Patent number: 7301041
    Abstract: The invention relates to bi-functionalised metallocenes of general formula (I) where Me=a transition metal, preferably chosen from Fe, Ru and Os, Y and Z, when identical are selected from —(CH2)n—O—, (CH2)—O—[(CH2)2—O]P— and —(CH2)q—CONH—(CH2)r—O—, or Y=—(CH2)S—NH— and Z=—(CH2)t—COO—, n=a whole number from 3 to 6 inclusive, p=a whole number from 1 to 4 inclusive, q=a whole number from 0 to 2 inclusive, r=a whole number from 0 to 2 inclusive, s=a whole number from 2 to 5 inclusive, t=a whole number from 3 to 6 inclusive, R and R?=H atoms or are protective groups used in oligonucleotide and peptide synthesis, where at least one of R or R? is protective group used in oligonucleotide and peptide synthesis and R and R? are as defined below: (i) when Z and Y are selected from (CH2)n—O—, —(CH2)—O—[(CH2)2—O]p— and —(CH2)q—CONH—(CH2)r—O—, then R and R? are protective groups used in oligonucleotide synthesis and R is a group which can leave a free OH group after deprotection, preferably a photolabile group such as mono
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: November 27, 2007
    Assignee: Bio Merieux
    Inventors: Carole Chaix-Bauvais, Corinne Moustrou, Aude-Emmanuelle Navarro, Hugues Brisset, Francis Garnier, Bernard Mandrand, Nicolas Spinelli
  • Patent number: 7301042
    Abstract: Rubber composition intended for the manufacture of tire casings which have improved hysteretic properties and scorch safety, based on at least one elastomer and silica by way of reinforcing filler enclosing a reinforcing additive consisting of the mixture and/or the product of in situ reaction of at least one functionalized polyorganosiloxane compound containing, per molecule, at least one functional siloxy unit capable of bonding chemically and/or physically to the surface hydroxyl sites of the silica particles and at least one functionalized organosilane compound containing, per molecule, at least one functional group capable of bonding chemically and/or physically to the polyorganosiloxane and/or the hydroxyl sites of the silica particles and at least one other functional group capable of bonding chemically and/or physically to the polymer chains.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: November 27, 2007
    Inventor: Richard W. Cruse
  • Patent number: 7301043
    Abstract: Compounds for determining the activity of phospholipase A2, are described herein, and include embodiments having formula (1) wherein L1 is derived from an ether (R1—OR2)m, wherein R1 and R2 are independently selected and are derived from a hydrocarbon having 1 to 12 carbon atoms, with m being an integer from 1 to 4, or from a hydrocarbon R having 1 to 20 carbon atoms; F is unsubstituted or substituted pyrene as a flouraphore; Q is a quencher, and L2 is C(O)-L1 or C(O)-L1-NH, wherein L1 is as defined above. These compounds may be used to determine the activity of phospholipase A2, in particular PAF-AH.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: November 27, 2007
    Assignee: Sirs-Lab GmbH
    Inventors: Hans-Peter Deigner, Stefan Russwurm, Ralf Kinscherf, Wolfgang Lösche
  • Patent number: 7301044
    Abstract: A process and intermediates for producing 3-amino nitrites. The process involves resolving an enantiomeric mixture of chiral 3-amino nitrites in the presence of a chiral acid in a solvent system to produce a chiral 3-amino nitrile salt. The process may further comprise a recrystalizing step, wherein an enantiomerically enriched 3-amino nitrile salt is produced. The process may further comprise a salt exchanging step, wherein another acid is added to the chiral 3-amino nitrile salt or the enantiomerically enriched 3-amino nitrile salt to produce another 3-amino nitrile salt.
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: November 27, 2007
    Assignee: Pfizer Inc.
    Inventors: David Robert Allen, Crystal A Achenbach-McCarthy
  • Patent number: 7301045
    Abstract: The present invention provides a method for preparing ester or thioester that can conduct catalytic esterification reaction with an equimolar amount of carboxylic acid and alcohol, or catalytic thioesterification reaction with carboxylic acid and an equimolar amount or small amount of thiol, and can be expected as an industrial method that needs an enormous amount of synthesis in the light of green chemistry. By using hafnium chloride (IV), especially tetravalent hafnium compounds represented by hafnium chloride (IV)·(THF)2 or hafnium (IV)t-butoxide as a (poly) condensation catalyst, direct condensation reaction is conducted from carboxylic acid and an equimolar amount of alcohol or a little smaller amount of thiol, in the nonpolar solvent such as toluene and the like, in a deoxidization atmosphere and under heating reflux, and the reaction synthesizes ester monomer or thioester monomer, polyester or polythioester.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: November 27, 2007
    Assignee: Japan Science and Technology Corporation
    Inventors: Kazuaki Ishihara, Hisashi Yamamoto
  • Patent number: 7301046
    Abstract: The present invention relates to optically active boronate derivatives which are useful as intermediates for the synthesis of HMG-CoA enzyme inhibitors such as atorvastatin, cerivastatin rosuvastatin, pitavastatin, and fluvastatin.
    Type: Grant
    Filed: February 25, 2002
    Date of Patent: November 27, 2007
    Assignee: Biocon Limited
    Inventors: Tom Thomas Puthiaparampil, Sumithra Srinath, Madhavan Sridharan, Sambasivam Ganesh
  • Patent number: 7301047
    Abstract: The present invention provides a salt of the formula (I): wherein ring X represents monocyclic or bicyclic hydrocarbon group having 3 to 30 carbon atoms, and one or more hydrogen atom in the ring X is optionally substituted with alkyl group having 1 to 6 carbon atoms, alkenyl group having 2 to 6 carbon atoms, alkoxy group having 2 to 6 carbon atoms or perfluoroalkyl group having 1 to 4 carbon atoms; Q1 and Q2 each independently represent fluorine atom or perfluoroalkyl group having 1 to 6 carbon atoms; A+ represents organic counter ion; and n shows an integer of 1 to 12. The present invention also provides a chemically amplified resist composition comprising the salt of the formula (I).
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: November 27, 2007
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Isao Yoshida, Yukako Harada, Satoshi Yamaguchi
  • Patent number: 7301048
    Abstract: A process for isolating vinyl acetate from the gas mixture formed in the reaction of ethylene with acetic acid and oxygen in the gas phase over catalysts comprising palladium or palladium compounds, with recirculation of the acetic-acid solution obtained in the circulating gas scrubber to the first distillation column (predewatering column).
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: November 27, 2007
    Assignee: Celanese Chemicals Europe GmbH
    Inventors: Johann Stamm, Bernd Rinne, Stefan Hess, Hans-Jochen Sachs, Michael Sehr, Michael J. Bayer, Berthold Nuber, Martin Wagner
  • Patent number: 7301049
    Abstract: Compounds which are capable of generating acid on photolysis are disclosed, and the uses of these compounds, especially for deprotecting the termini of nucleic acid molecules or peptides during synthesis of arrays. The compounds described herein may be employed in the detritylation of 5?-O-dimethoxytrityl (DMT) protected nucleotides by photolysing the compounds to generate an acid capable of removing the DMT group allowing oligonucleotide arrays to be synthesised using readily available 5?-O-DMT-nucleoside-3?-O-phosphoramidite monomers conventionally used in solid phase nucleic acid synthesis. A method of avoiding the effects of stray light in projection lithography techniques is also disclosed.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: November 27, 2007
    Assignee: The Institute of Cancer Research
    Inventors: Pawel Jerzy Serafinowski, Peter Bryan Garland
  • Patent number: 7301050
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: November 27, 2007
    Assignee: Janssen Pharmaceutical N.V.
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan R. DeAngelis
  • Patent number: 7301051
    Abstract: Disclosed are creatine salts having the general formula wherein A is a member of a group consisting of an anion of ketoglutaric acid and succinic acid.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: November 27, 2007
    Assignee: Starmark Laboratories
    Inventor: Matthias Boldt
  • Patent number: 7301052
    Abstract: The present invention provides a process for producing compounds useful as raw materials for various fluororesins in high yields in few steps from inexpensive and readily available starting materials. The following compound (1) and the following compound (2) are reacted to form the following compound (3), then the compound (3) is fluorinated in a liquid phase to form the following compound (4), and the ester bonds in the compound (4) are dissociated to form the compound (5), or the compound (5) and the compound (6). HOCH2-Q-O—(CH2)3—OH,??(1) CRBCOX,??(2) RBCOOCH2-Q-O—(CH2)3—OCORB,??(3) RBFCOOCF2-QF-O—(CF2)3—OCORBF,??(4) FCO-QF-O—(CF2)2—COF,??(5) RBFCOF.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: November 27, 2007
    Assignee: Asahi Glass Company, Linited
    Inventors: Shu-zhong Wang, Takashi Okazoe, Eisuke Murotani, Kunio Watanabe, Daisuke Shirakawa, Kazuya Oharu
  • Patent number: 7301053
    Abstract: An object of the present invention is to provide a modified cyclic aliphatic polyamine having a low viscosity and a small content of unreacted polyamine which can provide, when it is used as a curing agent for epoxy resin, an epoxy resin composition having an improved workability without adding solvent or diluent and an excellent property of epoxy resin cure product. The above modified cyclic aliphatic polyamine is obtained by addition reaction of a cyclic aliphatic polyamine such as isophoronediamine and norbornanediamine and an alkenyl compound such as styrene. The modified cyclic aliphatic polyamine thus obtained is added in epoxy resin to be used as a curing agent for epoxy resin.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: November 27, 2007
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Takeshi Koyama, Tetsushi Ichikawa, Hisayuki Kuwahara, Masatoshi Echigo
  • Patent number: 7301054
    Abstract: Disclosed are catalyst solutions for the hydroformylation of formaldehyde comprising one or more fluorophosphite compounds, rhodium and a hydroformylation solvent comprising at least one N,N-disubstituted amide, N-substituted cyclic amide, or a mixture thereof. Also disclosed are hydroformylation processes wherein formaldehyde is contacted with carbon monoxide, hydrogen one or more fluorophosphite compounds, rhodium and a hydroformylation solvent to produce glycolaldehyde. The fluorophosphite-based catalysts provide good reaction rates and high selectivity to glycolaldehyde.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: November 27, 2007
    Assignee: Eastman Chemical Company
    Inventor: Thomas Allen Puckette
  • Patent number: 7301055
    Abstract: Process for removing methanol from formaldehyde-containing solutions. The present invention relates to a process for removing methanol from formaldehyde-containing solutions, with methanol being converted into formaldehyde dimethyl acetal by reactive distillation in the presence of an acidic fixed-bed catalyst, and the resultant mixture comprising methanol, formaldehyde dimethyl acetal and possibly other impurities being distilled off.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: November 27, 2007
    Assignee: Ticona GmbH
    Inventors: Michael Hoffmockel, Matthias Göring, Juergen Lingnau, Karl-Friedrich Mück
  • Patent number: 7301056
    Abstract: A continuous process for the separation of phenol is disclosed. The process includes (a) feeding a stream of material, produced while preparing bisphenol A by reacting phenol with acetone, into a distillation column containing at least 5 theoretical separation stages, b) distilling-off the phenol as a top product and discharging from the column a bottom product containing secondary components, c) continuously introducing a portion of the bottom product into a dwell-time container operating at process parameters sufficient to cause, in the presence of an acidic catalyst, at least partial isomerization of the secondary components to form an isomerized product and d) introducing the isomerized product to the distillation column. The introducing of the bottom product is at a rate that is more than 30% of the rate of feeding of the stream at temperatures greater than 190° C. and hydrodynamic dwell time of at least 120 minutes.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: November 27, 2007
    Assignee: Bayer MaterialScience AG
    Inventors: Michael Prein, Rob Eek, Raymond Audenaert
  • Patent number: 7301057
    Abstract: The present invention relates to a process for preparing 3(4),8(9)-dihydroxymethyltricyclo[5.2.102.6]decane by hydrogenating the hyd roformylation products of d icyclopentad lene. The process comprises carrying out the hydrogenation in the presence of water, optionally after addition of water.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: November 27, 2007
    Assignee: Oxea Deutschland GmbH
    Inventors: Wolfgang Dukat, Edgar Storm, Klaus Schmid
  • Patent number: 7301058
    Abstract: The invention relates to a method for increasing yield in the production of polyvalent alcohols, especially trimethylolpropane, obtained by condensing formaldehyde with a higher aldehyde. According to the inventive method, acid treatment is carried out on a mixture (high-boiling fraction) that is obtained by reprocessing, contains derivatives of said alcohols and has a higher boiling point than the respective alcohol, and the polyvalent alcohol is recovered from the acid-treated high-boiling fraction. The inventive method is characterised in that the water content of the high-boiling fraction amounts to between 20 and 90 wt. % in relation to the entire mixture of the high-boiling fraction and water.
    Type: Grant
    Filed: July 18, 2003
    Date of Patent: November 27, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Alexander Wartini, Tilman Sirch, Johann-Peter Melder, Matthias Dernbach
  • Patent number: 7301059
    Abstract: Hexafluoroisobutylene and its higher homologs are easily reacted with SO3 to give fluorosulfates of the formula CH2?C(R)CF2OSO2F, wherein R is a linear branched or cyclic fluoroalkyl group comprised of 1 to 10 carbon atoms and may contain ether oxygen. These compounds react under mild conditions with many nucleophiles to give CH2?C(R)CF2X, where X is derived from the nucleophile. This reaction provides a route to many substituted hexafluoroisobutylenes, which copolymerize easily with other fluoro- and hydrocarbon monomers such as vinylidene fluoride and ethylene.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: November 27, 2007
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Victor Filippovich Cherstkov, Nina Ivanova Delyagina, Viacheslav A. Petrov, Weiming Qiu, Paul R. Resnick
  • Patent number: 7301060
    Abstract: The present invention addresses the processing of waste and low-value products to produce useful materials in reliable purities and compositions, at acceptable cost, and with high energy efficiency. In particular, the invention comprises a multi-stage process that converts various feedstocks such as offal, animal manures, municipal sewage sludge, that otherwise have little commercial value, to useful materials including gas, oil, specialty chemicals, and carbon solids. The process subjects the feedstock to heat and pressure in a reducing environment accomplished by controlled addition of sulfur and sodium, separates out various components, then further applies heat and pressure to one or more of those components. The invention further comprises an apparatus for performing a multi-stage process of converting waste products into useful materials, and at least one oil product that arises from the process.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: November 27, 2007
    Assignee: AB-CWT, LLC
    Inventors: Brian S. Appel, James H. Freiss, William F. Lange
  • Patent number: 7301061
    Abstract: The present invention is a utilization method for rubber-containing, organic industrial and municipal wastes which may be applied in the fields of petrochemical and chemical industry. Raw material is liquefied at 60-310° C. under 0.1-0.2 MP a pressure in aprotic hydrocarbon solvent in any neutral gas or CO2 atmosphere with simultaneous collection from reactor of liquid hydrocarbon fractions with the boiling temperatures reaching 200° C. and above and further rectification of fractions up to 200° C. and then drying solid residues at temperatures 270-310° C. Application of solvents and gases makes this process to be ecologically clean. The present invention makes possible a solution of the ecological problem of utilization of rubber-containing and other wastes.
    Type: Grant
    Filed: March 19, 2003
    Date of Patent: November 27, 2007
    Inventors: Igor Skworcow, Alexei Matveev
  • Patent number: 7301062
    Abstract: A process for the selective hydrogenation of one or more alkyne and/or one or more diene in an olefin-containing hydrocarbon feed includes contacting the hydrocarbon feed with a catalyst under selective hydrogenation conditions, the catalyst including from about 0.01 to about 0.1 weight percent palladium and from about 0.005 to about 0.6 weight percent of at least one Group IB metal incorporated into an inorganic support, wherein the surface area of the support is from about 2 to about 20 m2/g, the pore volume is greater than about 0.4 cc/g, at least about 90% of the pore volume is contained in pores with pore diameters larger than about 500 ?, and the pore volume of the pores with a pore diameter from about 500 to about 1,000 ? comprise from about 1% to about 2% of the total pore volume.
    Type: Grant
    Filed: July 27, 2004
    Date of Patent: November 27, 2007
    Assignee: ABB Lummus Global Inc.
    Inventors: Robert J. Gartside, Thomas Skourlis
  • Patent number: 7301063
    Abstract: A process for increasing the production of light olefin hydrocarbons from a hydrocarbon feedstock. A process for producing an aromatic hydrocarbon mixture and liquefied petroleum gas (LPG) from a hydrocarbon mixture, and a process for producing a hydrocarbon feedstock which is capable of being used as a feedstock in the former process, that is to say, a fluidized catalytic cracking (FCC) process, a catalytic reforming process, and/or a pyrolysis process, are integrated, thereby it is possible to increase the production of C2-C4 light olefin hydrocarbons.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: November 27, 2007
    Assignee: SK Corporation
    Inventors: Sun Choi, Seung Hoon Oh, Kyoung Hak Sung, Jong Hyung Lee, Sin Choel Kang, Yong Seung Kim, Byeung Soo Lim, Ahn Seop Choi, Byoung Mu Chang
  • Patent number: 7301064
    Abstract: Catalysts comprising a combination of molecular sieve having a pore diameter of from about 4 to 8 angstroms and a catalytically-effective amount of molybdenum hydrogenation component in an amorphous aluminum phosphate binder provide processes for isomerizing xylene and dealkylating ethylbenzene in feed streams that exhibit stability, selectivity and low ring loss.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: November 27, 2007
    Assignee: UOP LLC
    Inventors: Paula L. Bogdan, Patrick C. Whitchurch, Robert B. Larson, James E. Rekoske, Dimitri A. Trufanov, Victor C. Patton, Suheil F. Abdo
  • Patent number: 7301065
    Abstract: The invention relates to a molecular sieve catalyst composition, to a method of making or forming the molecular sieve catalyst composition, and to a conversion process using the catalyst composition. In particular, the invention is directed to making a formulated molecular sieve catalyst composition from a slurry of formulation composition of a synthesized molecular sieve that has not been fully dried, a binder and an optional matrix material. In a more preferred embodiment, the weight ratio of the binder to the molecular sieve and/or the solid content of the slurry is controlled to provide an improved attrition resistant catalyst composition, particularly useful in a conversion process for producing olefin(s), preferably ethylene and/or propylene, from a feedstock, preferably an oxygenate containing feedstock.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: November 27, 2007
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Stephen N. Vaughn, Yun-feng Chang, Luc R. M. Martens, Kenneth R. Clem, Machteld M. Mertens, Albert E. Schweizer
  • Patent number: 7301066
    Abstract: Methods of treating ground water and methods for reducing contaminants (e.g., chlorinated compounds in contaminated ground water) to harmless compounds in the presence of an elemental metal treatment composition. Said methods comprise injecting a treatment solution comprising a colloidal suspension of elemental metal particles (e.g., iron, a tin, a zinc, a palladium and mixtures thereof) having a nanoscale particle size and a carbohydrate in an organic liquid (e.g., dodecane, butyl acetate and polypropylene glycol ethyl ether acetate and mixtures thereof) into the ground, proximate to the contaminated ground water.
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: November 27, 2007
    Assignee: Arcadis G&M, Inc.
    Inventors: David Vance, Suthan S. Suthersan, Peter Palmer
  • Patent number: 7301067
    Abstract: Elastin, the main component of arterial extracellular matrix, was thought to have a purely structural role. Consistent with this view, elastin hemizygous mice maintain arterial extensibility by increasing the number of elastic lamellae during development. However, mice lacking elastin die of obstructive arterial pathology. This pathology results from subendothelial proliferation and reorganization of smooth muscle, cellular changes similar to those observed in atherosclerosis. Thus, elastin is a molecular determinant of arterial morphogenesis and likely plays a central role in vascular disease. Mice which are heterozygous and null for the elastin gene have been developed. These mice are extremely useful for screening for drugs useful for treating persons with atherosclerosis, hypertension, SVAS or other vascular diseases.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: November 27, 2007
    Assignee: University of Utah Research Foundation
    Inventors: Mark T. Keating, Dean Y. Li
  • Patent number: 7301068
    Abstract: An object of the present invention is to provide a nonhuman model animal of Th2-mediated hyperimmune response lacking PIR-B gene function on its chromosome by which the Th2-mediated immune response mechanism and allergy onset mechanism in vivo can be analyzed and which is liable to suffer from not only hyper-response of B cells but also allergy, and an inducer/promoter or an inhibitor for Th2-mediated immune response, etc. with the use of the nonhuman model animal of Th2-mediated hyperimmune response. The nonhuman model animal of Th2-mediated hyperimmune response is prepared by integrating a fragment comprising exons 1 to 7 and the domain in the 5? side of exon 8 of mouse PIR-B gene and another fragment containing exons 10 to 14 into a vector pMC1-Neo, cleaving it with Xho I-Sal I, integrating it into a vector pIC19R-MC1tk having herpes virus thymidine kinase to thereby construct targeting vector, transferring the targeting vector into ES cells and then injecting the ES cells into blastcyst.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: November 27, 2007
    Assignee: Japan Science and Technology Corporation
    Inventors: Toshiyuki Takai, Azusa Ujike-Asai
  • Patent number: 7301069
    Abstract: Methods for protecting a plant from a pathogen, particularly a pathogenic fungus or nematode, are provided. A method for enhancing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the embodiments, or variant or fragment thereof, are also disclosed.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: November 27, 2007
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Hana S. Ali, Robert J. Keenan, Michael Lassner, Mathias L. Muller, Gowri Shah, Jun-Zhi Wei, Gusui Wu
  • Patent number: 7301070
    Abstract: By this invention, compositions and methods of use related to ?-ketoacyl-ACP synthase Of special interest are synthases obtainable from Cuphea species. Amino acid and nucleic acid for synthase protein factors are provided, as well as methods to utilize such sequences in constructs for production of genetically engineered plants having altered fatty acid compositions. Of particular interest is the expression of synthase protein factors in conjunction with expression of plant medium-chain acyl-ACP thioesterases for production of increased levels and/or modified ratios of medium-chain fatty acids in oils of transgenic plant seeds.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: November 27, 2007
    Assignee: Calgene LLC
    Inventor: Katayoon Dehesh
  • Patent number: 7301071
    Abstract: The present invention relates to nucleotide sequences commonly designated CJAS1 comprising a novel gene from plants. The novel gene encodes a protein that is involved in seed formation and is associated with plant defense. The invention further relates to the use of the nucleotide sequence in the sense or antisense orientation to inhibit the expression of the plant gene corresponding to the CJAS1 sequence as a means to alter seed metabolism in plants, particularly cruciferous plants, more particularly Brassica species, to generate seeds with reduced fiber content and/or altered seed coats. The invention also relates to similar genes expressed in other plant species. The invention also relates to the discovery that the CJAS1 gene is involved in proanthocyanidin (PA) formation.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: November 27, 2007
    Assignee: National Research Council of Canada
    Inventors: Zhifu Zheng, Tina Uchacz, Janet Taylor
  • Patent number: 7301072
    Abstract: A soybean cultivar, designated S040125, is disclosed. The invention relates to the seeds of soybean cultivar S040125, to the plants of soybean S040125, to plant parts of soybean cultivar S040125 and to methods for producing a soybean plant produced by crossing soybean cultivar S040125 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean variety S040125, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S040125 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing the cultivar S040125 with another soybean cultivar.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: November 27, 2007
    Assignee: Mertec LLC
    Inventor: Dennis L. Schultze
  • Patent number: 7301073
    Abstract: A soybean cultivar designated 4405070 is disclosed. The invention relates to the seeds of soybean cultivar 4405070, to the plants of soybean 4405070, to plant parts of soybean cultivar 4405070 and to methods for producing a soybean plant produced by crossing soybean cultivar 4405070 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean variety 4405070, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 4405070 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing the cultivar 4405070 with another soybean cultivar.
    Type: Grant
    Filed: January 29, 2005
    Date of Patent: November 27, 2007
    Assignee: Mertec LLC
    Inventor: Dennis L. Schultze
  • Patent number: 7301074
    Abstract: Disclosed is the seed of a novel soybean cultivar, designated 5.8 i, a sample of which is deposited under ATCC Accession No. PTA-7274. Also disclosed are plants, or parts thereof, grown from the seed of the cultivar, plants having the morphological and physiological characteristics of the 5.8 i cultivar, and methods of using the plants or parts thereof in a soybean breeding program.
    Type: Grant
    Filed: September 22, 2005
    Date of Patent: November 27, 2007
    Assignee: Dairyland Seed Co., Inc.
    Inventors: Robert E. Moore, Jr., Marcos Quiroga Guiraldes
  • Patent number: 7301075
    Abstract: According to the invention, there is provided a novel soybean variety designated XB28T06. This invention thus relates to the seeds of soybean variety XB28T06, to the plants of soybean XB28T06 to plant parts of soybean variety XB28T06 and to methods for producing a soybean plant produced by crossing plants of the soybean variety XB28T06 with another soybean plant, using XB28T06 as either the male or the female parent.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: November 27, 2007
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Paul Alan Stephens, Debra Kay Steiger
  • Patent number: 7301076
    Abstract: A soybean cultivar designated S050231 is disclosed. The invention relates to the seeds of soybean cultivar S050231, to the plants of soybean S050231, to plant parts of soybean cultivar S050231 and to methods for producing a soybean plant produced by crossing soybean cultivar S050231 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean variety S050231, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S050231 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing the cultivar S050231 with another soybean cultivar.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: November 27, 2007
    Assignees: Stine Seed Farm, Inc., Monsanto Technology LLC
    Inventor: William H. Eby
  • Patent number: 7301077
    Abstract: A soybean cultivar designated 26143837 is disclosed. The invention relates to the seeds of soybean cultivar 26143837, to the plants of soybean 26143837, to plant parts of soybean cultivar 26143837 and to methods for producing a soybean plant produced by crossing soybean cultivar 26143837 with itself or with another soybean cultivar. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean cultivar 26143837, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 26143837 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing cultivar 26143837 with another soybean cultivar.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: November 27, 2007
    Assignee: Mertec LLC
    Inventor: Dennis L. Schultze
  • Patent number: 7301078
    Abstract: A soybean cultivar designated 26312034 is disclosed. The invention relates to the seeds of soybean cultivar 26312034, to the plants of soybean 26312034, to plant parts of soybean cultivar 26312034 and to methods for producing a soybean plant produced by crossing soybean cultivar 26312034 with itself or with another soybean cultivar. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars or breeding cultivars and plant parts derived from soybean cultivar 26312034, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 26312034 and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants and plant parts produced by crossing cultivar 26312034 with another soybean cultivar.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: November 27, 2007
    Assignee: Mertec LLC
    Inventor: Dennis L. Schultze
  • Patent number: 7301079
    Abstract: An inbred maize line, designated PH6MN, the plants and seeds of inbred maize line PH6MN, methods for producing a maize plant, either inbred or hybrid, produced by crossing the inbred maize line PH6MN with another maize plant, and hybrid maize seeds and plants produced by crossing the inbred line PH6MN with another maize line or plant and to methods for producing a maize plant containing in its genetic material one or more transgenes and to the transgenic maize plants produced by that method. This invention also relates to inbred maize lines derived from inbred maize line PH6MN, to methods for producing other inbred maize lines derived from inbred maize line PH6MN and to the inbred maize lines derived by the use of those methods.
    Type: Grant
    Filed: December 30, 2004
    Date of Patent: November 27, 2007
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventor: David L. Benson
  • Patent number: 7301080
    Abstract: An inbred maize line, designated PH8DB, the plants and seeds of inbred maize line PH8DB, methods for producing a maize plant, either inbred or hybrid, produced by crossing the inbred maize line PH8DB with another maize plant, and hybrid maize seeds and plants produced by crossing the inbred line PH8DB with another maize line or plant and to methods for producing a maize plant containing in its genetic material one or more transgenes and to the transgenic maize plants produced by that method. This invention also relates to inbred maize lines derived from inbred maize line PH8DB, to methods for producing other inbred maize lines derived from inbred maize line PH8DB and to the inbred maize lines derived by the use of those methods.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: November 27, 2007
    Assignee: Pioneer Hi-Bread International, Inc.
    Inventors: William Andrew Wilson, Loren John Hoffbeck
  • Patent number: 7301081
    Abstract: According to the invention, there is provided seed and plants of the corn variety designated I059952. The invention thus relates to the plants, seeds and tissue cultures of the variety I059952, and to methods for producing a corn plant produced by crossing a corn plant of variety I059952 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety I059952 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety I059952.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: November 27, 2007
    Inventors: Michael J. Graham, Marcelo Queijo
  • Patent number: 7301082
    Abstract: A novel inbred maize line designated PHEBA and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing inbred maize line PHEBA with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHEBA through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the inbred line PHEBA or a trait conversion of PHEBA with another maize line. Inbred maize lines derived from inbred maize line PHEBA, methods for producing other inbred maize lines derived from inbred maize line PHEBA and the inbred maize lines and their parts derived by the use of those methods.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: November 27, 2007
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventor: Lora Lynn Kilgore-Norquest
  • Patent number: 7301083
    Abstract: A rice hybrid designated XL730 is disclosed. The invention relates to the seeds of rice hybrid XL730, to the plants of rice hybrid XL730 and to methods for producing a rice plant produced by crossing the hybrid XL730 with itself or another rice plant. The invention further relates to hybrid rice seeds and plants produced by crossing the hybrid XL730 with another rice plant.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: November 27, 2007
    Assignee: Ricetec, AG
    Inventors: Eugenio S. Sarreal, Barry L. Tillman
  • Patent number: 7301084
    Abstract: An upright keyboard musical instrument has an open/close board attached to the top position of a case, wherein the lower surface of the open/close board is subjected to mirror surface finishing and is supported by a lid prop, which is rotatably arranged in proximity to the top board to rotate about a support axis and is formed in an L-shape to have a plurality of support surfaces, realizing different angles for the open/close board being opened. The mirror surface of the open/close board projects images representing internal members of the case, such as an emblem and actions. By appropriately rotating the lid prop, it is possible to realize a desired angle for the open/close board, thus realizing tone volume control and visually entertaining effects in musical performance.
    Type: Grant
    Filed: March 25, 2005
    Date of Patent: November 27, 2007
    Assignee: Yamaha Corporation
    Inventor: Keita Okada
  • Patent number: 7301085
    Abstract: A stringed musical instrument is provided with a plate or soundboard that is curved to define a crest parallel to the strings. If the instrument is a closedbox instrument, another plate opposing the first plate may be curved to define a crest perpendicular to the strings. The first plate may be supported by transverse braces, which are scalloped to leave substantial air gaps along the glue line once the brace is attached. The back plate may be supported by a substantial longitudinal brace or spine, which runs down its center parallel to the strings. The spine contains a substantial portion of the mass of the back plate. These musical instruments have reduced wolf tones and improved harmonic generation over common instruments, and therefore have a more complex and pleasing tone than common instruments. The harmonic character of these instruments is fully exploited by using one or more harmonic bridges in addition to the primary bridge.
    Type: Grant
    Filed: December 23, 2005
    Date of Patent: November 27, 2007
    Inventor: Kevin Alexander Wyman
  • Patent number: 7301086
    Abstract: A tailpiece of, for instance, an electric guitar including a bridge main body attached to the guitar main body by two protruding stud screws so as to be moved and adjusted in the direction of the stretched strings. At both ends of the bridge main body, first and second string supports for supporting first and sixth strings are formed integrally to protrude inwardly. Between the first and second string supports, a first bridge saddle member for supporting the second and third strings, and a second bridge saddle member for supporting the fourth and fifth strings, are provided. These saddles are connected to the bridge main body by saddle adjustment screws so as to be moved and adjusted in the forward and backward direction. The first and second bridge saddle members are moved along the surfaces parallel to the direction of the stretched strings.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: November 27, 2007
    Assignee: Yamaha Corporation
    Inventor: Osamu Ito