Patents Issued in July 17, 2008
  • Publication number: 20080170989
    Abstract: The present application discloses compositions and methods of synthesis and use of F-18 labeled molecules of use, for example, in PET imaging techniques. In particular embodiments, the labeled molecules may be peptides or proteins, although other types of molecules including but not limited to aptamers, oligonucleotides and nucleic acids may be labeled and utilized for such imaging studies. In preferred embodiments, the F-18 label may be conjugated to a targeting molecule by formation of a metal complex and binding of the F-18-metal complex to a chelating moiety, such as DOTA, NOTA, DTPA, TETA or NETA. In other embodiments, the metal may first be conjugated to the chelating group and subsequently the F-18 bound to the metal. In other preferred embodiments, the F-18 labeled moiety may comprise a targetable conjugate that may be used in combination with a bispecific or multispecific antibody to target the F-18 to an antigen expressed on a cell or tissue associated with a disease, medical condition, or pathogen.
    Type: Application
    Filed: December 19, 2007
    Publication date: July 17, 2008
    Applicant: IMMUNOMEDICS, INC.
    Inventors: William J. McBride, David M. Goldenberg
  • Publication number: 20080170990
    Abstract: The present application discloses methods for myocardial imaging in human patients having a history of pulmonary disease such as asthma, bronchospasm, chronic obstructive pulmonary disease, pulmonary fibrosis, pulmonary inflammation, or pulmonary hypertension, comprising administrating doses of one or more A2A adenosine receptor agonists to a mammal undergoing myocardial imaging and detecting and/or diagnosing myocardial dysfunction.
    Type: Application
    Filed: September 28, 2007
    Publication date: July 17, 2008
    Applicant: CV THERAPEUTICS, INC.
    Inventors: Hsiao D. Lieu, Brent Blackburn, Luiz Belardinelli
  • Publication number: 20080170991
    Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.
    Type: Application
    Filed: September 6, 2007
    Publication date: July 17, 2008
    Inventors: Wenyuan Shi, Randal H. Eckert, Daniel K. Yarbrough, Fengxia Qi, Jian He, Ian H. McHardy, Maxwell H. Anderson
  • Publication number: 20080170992
    Abstract: The present application is directed to radiolabeled cyclic polypeptides, pharmaceutical compositions comprising radiolabeled cyclic polypeptides, and methods of using the radiolabeled cyclic polypeptides. Such polypeptides can be used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
    Type: Application
    Filed: September 17, 2007
    Publication date: July 17, 2008
    Inventors: Hartmuth C. Kolb, Kai Chen, Joseph C. Walsh, Qianwa Liang, Henry Clifton Padgett, Farhad Karimi
  • Publication number: 20080170993
    Abstract: The present invention relates to nucleoside analogues and more particularly to labeled nucleoside analogues. It has been found new thymidine analogues can be stably labeled with a detectable label moiety. Further the present invention relates to methods of making above compounds and use of such compounds for diagnostic imaging of tumor cells and/or treatment of proliferative diseases. In addition, the present invention relates to the preparation and use of positron emitting compounds for positron emission tomography (PET). A kit is also disclosed.
    Type: Application
    Filed: October 24, 2007
    Publication date: July 17, 2008
    Inventors: Ananth SRINIVASAN, Ulrike Voigtmann, Mathias Berndt, Keith Grahan, Sabine Zitzmann, Lutz Lehmann, Ansgar Fitzner
  • Publication number: 20080170994
    Abstract: The invention provides diagnostic and therapeutic macromolecular compositions that cross the blood-brain barrier, in some embodiments in both directions, while allowing their activity to remain substantially intact once across the barrier. Also provided are methods for using such compositions in the diagnosis or treatment of CNS disorders such as Alzheimer's disease.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 17, 2008
    Applicant: ARMAGEN TECHNOLOGIES, INC.
    Inventors: William M. Pardridge, Ruben J. Boado
  • Publication number: 20080170995
    Abstract: Buccal aerosol sprays or capsules using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal polar compositions of the invention comprise formulation I: aqueous polar solvent, active compound, and optional flavoring agent; formulation II: aqueous polar solvent, active compound, optionally flavoring agent, and propellant; formulation III: non-polar solvent, active compound, and optional flavoring agent; and formulation IV: non-polar solvent, active compound, optional flavoring agent, and propellant.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 17, 2008
    Inventor: Harry A. Dugger
  • Publication number: 20080170996
    Abstract: Embodiments of the invention include compositions, formulations and methods for the enhancement of a subject's biological defenses against infection, for example the subject's innate immunity against infection. Aspects of the invention provide a rapid and temporal enhancement or augmentation of biological defenses against microbial infection.
    Type: Application
    Filed: July 30, 2007
    Publication date: July 17, 2008
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Burton F. Dickey, Michael Tuvim, Cecilia G. Clement
  • Publication number: 20080170997
    Abstract: Compositions are provided for the topical treatment of cancer consisting of lotions, creams, sprays, suppositories or slow-release transdermal patches containing lipid-soluble, skin-penetrating organic selenium compounds in combination with inert carriers in therapeutically effective amounts of selenium compound. The selenium compounds are medium linear chain dialkyl diselenides and precursors such as alkyl selenols. Preferred compositions employ R—Se—Se—R compounds where R is from 6 to 8 carbon atoms, and most specifically di-n-hexyl diselenide. Commonly used carriers may be purified hydrocarbon fractions, oils, with or without added fat-soluble vitamins, water and emulsifying agents.
    Type: Application
    Filed: March 18, 2008
    Publication date: July 17, 2008
    Inventor: Gerhard N. Schrauzer
  • Publication number: 20080170998
    Abstract: The invention relates to a composition for treating or preventing an oral cavity by preventing adhesion of Porphyromonas gingivalis as periodontopathic bacterium to oral tissue. The invention also relates to a composition for treating or preventing an oral cavity containing a peptide in which arginine and histidine bind alternately. Preferably, the invention includes a composition for treating or preventing an oral cavity including the peptide of a pentamer of (arginine-histidine).
    Type: Application
    Filed: February 26, 2008
    Publication date: July 17, 2008
    Inventors: Satoshi Shizukuishi, Hideki Nagata, Jun Hiraki, Masami Todokoro
  • Publication number: 20080170999
    Abstract: Use of a compound of formula (I) where R1 is a C4-6 alkylene linkage optionally substituted by a C1-4alkyl group; R2 is ?NH, —NH2 or —OH; R3 is C1-5 alkyl optionally terminated by a hydroxy, phenyl or a 5- or 6-membered heterocyclic group such as furyl or N-imidazolyl and R4 is H; or R3 and R4 together form a C3-5 alkylene linkage; to produce a topical refreshing or cooling sensation in a mammal such as a human.
    Type: Application
    Filed: November 7, 2005
    Publication date: July 17, 2008
    Inventors: Alison Jayne Foster, Cornelis Paul Erik Van De Logt, Afrodite Lourbakos, Erwin Werner Tareilus
  • Publication number: 20080171000
    Abstract: The present invention is directed to a tooth surface mineralizing composition including a stabilized tooth mineralizing mineral composition containing calcium and phosphate and a dissociable source of a mineral that provides a mineral ionic species selected from calcium and phosphate upon dissociation.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 17, 2008
    Inventors: Emil E. Engelman, Robert J. Gambogi, Deepak Sharma
  • Publication number: 20080171001
    Abstract: The present invention is directed to a tooth cleaning and mineralizing composition including an abrasive composition in an amount sufficient to provide the tooth cleaning and mineralizing composition with a relative dental abrasion of from 100 to 250; and a stabilized tooth mineralizing mineral composition.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 17, 2008
    Inventors: Emil E. Engelman, Robert J. Gambogi, Deepak Sharma
  • Publication number: 20080171002
    Abstract: Phosphorylated glucomannan polysaccharide compositions are shown to effectively enhance healthy immune function. Dosage forms including pills, sprays, functional foods and cosmetics may achieve this benefit while being essentially free of storage protein from nongerminated seeds of Ricinus communis.
    Type: Application
    Filed: July 20, 2007
    Publication date: July 17, 2008
    Applicant: GOURMETCEUTICALS, LLC
    Inventors: Jose Antonio Matji Tuduri, Antonio F. Guerrero Gomez-Pamo, Jose Luis Alonso Lebrero, Garrett Lindemann, Manuel Lopez Cabrera, Pedro Majano Rodriguez, Ricardo Moreno Otero, Diego Serrano Gomez, Angel Corbi Lopez, Samuel Martin Vilchez
  • Publication number: 20080171003
    Abstract: The present invention discloses a process of preparing jambu extract that results in a jambu extract free from chlorophyll and derivatives of this compound. It is a method for isolating the components of interest in a simplified way, with quite high process yield, higher than 85%. The present invention further relates to the use of this extract in preparing cosmetic compositions, the cosmetic compositions comprising said extract, and to cosmetic products comprising said cosmetic compositions.
    Type: Application
    Filed: March 21, 2006
    Publication date: July 17, 2008
    Inventors: Sergio Delarcina, Jose Renato Cagnon, Alexandre Roberto Silva, Viviane Emi Nakano Fukusawa
  • Publication number: 20080171004
    Abstract: The present invention relates to the use of compounds which do not themselves exhibit significant UV absorption in the UV-A or UV-B region, but are reactive under use conditions, for the development of UV-A or UV-B protection during use, to corresponding novel compounds and compositions, and to corresponding processes for the preparation of compounds and compositions.
    Type: Application
    Filed: March 21, 2006
    Publication date: July 17, 2008
    Inventors: Thomas Rudolph, Herwig Buchholz
  • Publication number: 20080171005
    Abstract: Disclosed herein is a composition for make-up and/or care of the skin comprising a fatty phase, comprising: at least one resin of number average molecular weight less than or equal to 10,000 g/mol, selected from rosin, derivatives of rosin, and hydrocarbon resins, at least one hydrocarbon block copolymer, at least one fatty substance whose melting point is greater than 25° C. chosen from waxes and pasty fatty substances, wherein said composition comprises less than 5% of volatile oil.
    Type: Application
    Filed: December 19, 2007
    Publication date: July 17, 2008
    Inventors: Veronique Jacques, Veronique Schwartz, Xavier Blin, Philippe Ilekti
  • Publication number: 20080171006
    Abstract: The present invention is directed to a method of making up keratinous substrates involving applying onto the keratinous substrate a composition containing a) a block copolymer, b) a tackifier, c) an alkyl silsesquioxane wax, d) a liquid fatty phase, and e) optionally, a colorant.
    Type: Application
    Filed: January 10, 2008
    Publication date: July 17, 2008
    Applicant: L'OREAL
    Inventors: Hy Si BUI, Ann Marie Rohmeyer, Padraig McDermott
  • Publication number: 20080171007
    Abstract: A method of making up keratinous substrates involving applying onto the keratinous substrates a composition containing a) a block copolymer, b) a tackifier, c) a wax, d) a liquid fatty phase, e) a high viscosity ester, and f) optionally, a colorant.
    Type: Application
    Filed: January 10, 2008
    Publication date: July 17, 2008
    Applicant: L'OREAL
    Inventor: Hy Si BUI
  • Publication number: 20080171008
    Abstract: The invention relates to a physiologically acceptable composition, especially a cosmetic composition, comprising (a) at least one polyorganosiloxane containing polymer comprising at least one moiety which comprises at least one polyorganosiloxane group consisting of 1 to about 1000 organosiloxane units in the chain of the moiety or in the form of graft, and at least two groups capable of establishing hydrogen interactions; (b) at least one tackifier; (c) at least one block copolymer; and (d) at least one wax, as well as to methods of using such compositions and kits containing such compositions.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 17, 2008
    Applicant: L'Oreal S.A.
    Inventor: Hy Si BUI
  • Publication number: 20080171009
    Abstract: Keratin fibre makeup kit containing at least: a first composition with a surface energy of less than or equal to 30 mN/m, and a second composition with a surface energy such that the difference between its surface energy and that of the first composition is greater than or equal to 5 mN/m, and a viscosity of between 0.001 and 2 Pa·s.
    Type: Application
    Filed: January 4, 2008
    Publication date: July 17, 2008
    Applicant: L'OREAL
    Inventors: Frederic AUGUSTE, Jean-Yves Fouron
  • Publication number: 20080171010
    Abstract: The present disclosure relates to a treatment of the hair, which is resistant to shampooing operations, wherein the individual hairs are coated with a cosmetic composition comprising a polysiloxane/polyurea block copolymer wherein at least one volatile nonsilicone organic solvent and at least one silicone compound exhibit a viscosity of less than 100 cSt.
    Type: Application
    Filed: October 25, 2007
    Publication date: July 17, 2008
    Inventor: Gaelle Brun
  • Publication number: 20080171011
    Abstract: The disclosure herein is directed to organic skin-based products that comprise an excess of 70% organic ingredients. The skin care products described herein are composed of a plurality of organic juices and other organic materials.
    Type: Application
    Filed: November 1, 2007
    Publication date: July 17, 2008
    Applicant: JUICE BEAUTY
    Inventors: Melissa Jochim, Karen Behnke
  • Publication number: 20080171012
    Abstract: The invention provides surface treatments that reduce or eliminate marine biofouling of various surfaces. A surface that is to be subjected to a marine environment can be treated with a mPEG-DOPA. The treated surface is thus rendered less susceptible to fouling of the surface.
    Type: Application
    Filed: January 10, 2008
    Publication date: July 17, 2008
    Inventors: Phillip Messersmith, Andrea R. Statz, Bruce P. Lee, Jeffrey L. Dalsin, Daniel Sherman
  • Publication number: 20080171013
    Abstract: Improved posaconazole-based compositions and methods of treating and preventing fungal infections, cancer or metastatic diseases are disclosed. In preferred aspects, the conjugates are PEG-posaconazole conjugates in which the PEG has a molecular weight of about 20,000 daltons.
    Type: Application
    Filed: January 15, 2008
    Publication date: July 17, 2008
    Applicant: ENZON PHARMACEUTICALS, INC.
    Inventor: Hong Zhao
  • Publication number: 20080171014
    Abstract: The present invention encompasses IL-13 binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hIL-13 and neutralize hIL-13 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-13 and for inhibiting hIL-13 activity, e.g., in a human subject suffering from a disorder in which hIL-13 activity is detrimental.
    Type: Application
    Filed: September 7, 2007
    Publication date: July 17, 2008
    Inventors: Chengbin Wu, Richard W. Dixon, Jonathan P. Belk, Maria A. Argiriadi, Hua Ying, Carolyn A. Cuff, Terry L. Melim, Shankar Kumar, Paul R. Hinton, Yan Chen
  • Publication number: 20080171015
    Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
    Type: Application
    Filed: January 9, 2008
    Publication date: July 17, 2008
    Inventors: John A. Bender, Min Ding, Robert G. Gentles
  • Publication number: 20080171016
    Abstract: The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins that are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are antibodies and fragments thereof that bind to polypeptides of the invention. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.
    Type: Application
    Filed: March 11, 2008
    Publication date: July 17, 2008
    Applicant: Human Genome Sciences, Inc.
    Inventors: Guo-Liang Yu, Jian Ni, Reiner L. Gentz, Patrick J. Dillon
  • Publication number: 20080171017
    Abstract: A method for the treatment of proliferative disease or infectious disease, comprising administering to the patient an effective amount of a CD25 binding molecule.
    Type: Application
    Filed: April 13, 2006
    Publication date: July 17, 2008
    Inventor: Andreas Katopodis
  • Publication number: 20080171018
    Abstract: Adenovirus serotypes differ in their natural tropism. The adenovirus serotypes 2, 4, 5 and 7 all have a natural affiliation towards lung epithelia and other respiratory tissues. In contrast, serotypes 40 and 41 have a natural affiliation towards the gastrointestinal tract. The serotypes described, differ in at least capsid proteins (penton-base, hexon), proteins responsible for cell binding (fiber protein), and proteins involved in adenovirus replication. This difference in tropism and capsid protein among serotypes has led to the many research efforts aimed at redirecting the adenovirus tropism by modification of the capsid proteins.
    Type: Application
    Filed: October 29, 2007
    Publication date: July 17, 2008
    Applicant: Crucell Holland B.V.
    Inventors: Abraham Bout, Menzo Havenga, Ronald Vogels
  • Publication number: 20080171019
    Abstract: The present invention is directed to compositions of fetal hematopoietic stem and progenitor cells and stromal (mesencymal) cells derived from second trimester (16-20 weeks gestation) miscarriages, that are isolated, processed and cryopreserved, and the therapeutic uses of such stem and progenitor cells upon application. Such compositions may be useful for hematopoietic reconstitution and/or replacement in patients with various diseases and metabolic disorders. The invention also relates to methods for collecting, isolating, processing and cryopreserving of the fetal stem and progenitor cells of the invention. Importantly, the invention meets an urgent need in regenerative medicine while at the same time ensures utility of the product compositions because it utilizes fetal materials from second trimester (16-20 weeks of gestation) spontaneously lost pregnancies which are free of moral or ethical burdens.
    Type: Application
    Filed: January 17, 2007
    Publication date: July 17, 2008
    Inventor: Maria Michejda
  • Publication number: 20080171020
    Abstract: The present invention is directed to the expansion, preferably TVEMF-expansion, of mammalian blood adult stem cells, wherein the expansion takes place in a rotating bioreactor, preferably a TVEMF-bioreactor, to compositions resulting from the expanded cells, and to a method of treating an epithelial cell/tissue related disease or condition or repairing tissue of skin, mouth or ear with the compositions.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 17, 2008
    Inventor: Donnie Rudd
  • Publication number: 20080171021
    Abstract: The present invention relates to the treatment of disorders using nitric oxide (NO), heme oxygenase-1 (HO-1) and heme degradation products such as carbon monoxide (CO), biliverdin, bilirubin and iron.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 17, 2008
    Applicants: Beth Israel Deaconess Medical Center, Inc., University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Fritz H. Bach, Leo E. Otterbein
  • Publication number: 20080171022
    Abstract: Methods and systems are provided to facilitate treatment for a neoplastic disease include providing information of stem cells that can be isolated from an individual prior to diagnosis with a neoplastic disease; processing and storing the stem cells, such as cord blood or bone marrow stem cells, in a format suitable for transfusion; providing information that treatment of the individual after diagnosis with the neoplastic disease includes bone marrow ablation in addition to at least one of surgery, chemotherapy, and radiation therapy; and releasing the stem cells for administration to the individual to repopulate the bone marrow after ablation.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 17, 2008
    Inventor: Herbert Zech
  • Publication number: 20080171023
    Abstract: Methods and compositions for use of human dendritic cells to activate T cells for immunotherapeutic responses against primary and metastatic cancer are disclosed. In one embodiment, human dendritic cells exposed to a tumor associated antigen, or an antigenic fragment thereof in combination with bacillus Calmette-Guerin (BCG), are administered to a cancer patient to activate a predominantly CD8+T cell response in vivo. In an alternate embodiment, human dendritic cells are exposed to a tumor associated antigen or a specific antigenic peptide in combination with BCG in vitro and incubated or cultured with primed or unprimed T cells to activate a predominantly CD8+T cell response in vitro. The activated T cells are then administered to a cancer patient. Antigen in combination with BCG is processed by dendritic cells through the MHC-CLASS I compartment which provides for a predominantly CD8+T cell response.
    Type: Application
    Filed: January 10, 2008
    Publication date: July 17, 2008
    Applicant: NORTHWEST BIOTHERAPEUTICS, INC.
    Inventors: Michael Salgaller, Alton Boynton
  • Publication number: 20080171024
    Abstract: A method for preventing bacterial biofilm formation in a blood product, the method comprising modifying a blood product with a polymer selected from the group consisting of polyethylene glycol (PEG), PEG derivatives and mixtures thereof. Preventing bacterial biofilm formation in this way increases the planktonic to adherent ratio of any contaminating bacteria, and thereby facilitates detection of bacterial contamination.
    Type: Application
    Filed: December 21, 2007
    Publication date: July 17, 2008
    Inventors: Sandra M. Ramirez-Arcos, Elisabeth Maurer, Mark Scott
  • Publication number: 20080171025
    Abstract: The present invention is directed to methods of transfecting cells with siRNA, by contacting a transfection complex with one or more cells, where the transfection complex includes a transport polymer and siRNA. The transport polymer may include for example, H3K8b and/or structurally similar compounds. The invention is also directed to such transfection complexes, and to compositions that include such transfection complexes. The invention is further directed to methods of treating patients using the transfection complexes of the present invention.
    Type: Application
    Filed: November 17, 2005
    Publication date: July 17, 2008
    Inventor: Archibald Mixson
  • Publication number: 20080171026
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 17, 2008
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francis-Loic Cosset, Roberto Cattaneo
  • Publication number: 20080171027
    Abstract: Disclosed are compositions comprising a recombinant nucleic acid vector including a nucleotide sequence encoding a syncytium-inducing polypeptide expressible on a eukaryotic cell surface, and a host cell containing the recombinant vector and expressing the syncytium inducing polypeptide on its cell surface, the vectors and resultant host cells expressing the syncytium inducing polypeptide being useful for selective elimination of unwanted cells.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 17, 2008
    Inventors: Stephen James Russell, Frances Joanne Morling, Adele Kay Fielding, Francois-Loic Cosset, Roberto Cattaneo
  • Publication number: 20080171028
    Abstract: Microbial starter cultures. More specifically, a method for preparing a microbial starter culture wherein the microorganism is inoculated in a culture medium comprising at least one 5 yield enhancing agent selected from the group consisting of a purine base, a pyrimidine base, a nucleoside and a nucleotide. Such microbial starter cultures are useful in the manufacturing of food, feed and pharmaceutical products.
    Type: Application
    Filed: January 5, 2006
    Publication date: July 17, 2008
    Inventors: Borge Windel Kringelum, Niels Martin Sorensen, Christel Garrigues, Martin B. Pedersen, Susanne Gron
  • Publication number: 20080171029
    Abstract: A beauty mask uses natural material, like coconut milk, royal jelly, vegetable enzymes, aloe and loofah, for achieving a whitening, anti-wrinkle and moisturizing effect without further additives, thereby avoiding skin injuries, and which can be stored for a long time; furthermore a method for packing and storing beauty masks, by inserting separating foils between beauty masks and comprising steps of packing, sealing and freezing, prevents beauty masks from sticking together, so that beauty masks are storable for a long time and easily dispensable.
    Type: Application
    Filed: January 12, 2007
    Publication date: July 17, 2008
    Inventor: Jyh-Hau Lee
  • Publication number: 20080171030
    Abstract: The disclosure herein is directed to organic skin-based products that comprise an excess of 70% organic ingredients. The skin care products described herein are composed of a plurality of organic juices and other organic materials.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 17, 2008
    Applicant: JUICE BEAUTY
    Inventors: MELISSA JOCHIM, KAREN BEHNKE
  • Publication number: 20080171031
    Abstract: The disclosure herein is directed to organic skin-based products that comprise an excess of 70% organic ingredients. The skin care products described herein are composed of a plurality of organic juices and other organic materials.
    Type: Application
    Filed: November 1, 2007
    Publication date: July 17, 2008
    Applicant: JUICE BEAUTY
    Inventors: Melissa Jochim, Karen Behnke
  • Publication number: 20080171032
    Abstract: Described are compositions comprising a combination of superoxide dismutase and at least one member selected from the group consisting of astaxanthin, tocotrienol, carnosine, and benfotiamine, and methods of using the same for ameliorating or preventing the detrimental effects of oxidative stress.
    Type: Application
    Filed: January 14, 2008
    Publication date: July 17, 2008
    Inventor: Gregory J. Kelly
  • Publication number: 20080171033
    Abstract: Pharmaceutical compositions and methods for treating diseases associated with angiogenesis and inflammation. The invention relates to a pharmaceutical composition that includes a therapeutically effective amount of sCD26 and/or a biologically active derivative thereof and a pharmaceutically acceptable carrier. The composition may further include a therapeutically effective amount of sFlt-1 and/or a biologically active derivative thereof. Additionally, the invention relates to methods for treating a disease associated with and/or progresses by an inflammatory cytokine-associated inflammation and/or VEGF-associated angiogenesis.
    Type: Application
    Filed: December 24, 2007
    Publication date: July 17, 2008
    Inventor: Chiwen Chang
  • Publication number: 20080171034
    Abstract: Compounds, compositions and methods for treating degenerative diseases and disorders are disclosed, the compounds having the following structure (I): including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined herein.
    Type: Application
    Filed: October 25, 2007
    Publication date: July 17, 2008
    Applicant: MIGENIX Corp.
    Inventor: Yazhong Pei
  • Publication number: 20080171035
    Abstract: The purification and isolation of various genes which encode mammalian cell surface polypeptides. Nucleic acids, proteins, antibodies, and other reagents useful in modulating development of cells, e.g., lymphoid and myeloid, are provided, along with methods for their use.
    Type: Application
    Filed: January 25, 2008
    Publication date: July 17, 2008
    Applicant: SCHERING CORPORATION
    Inventors: Alexander B.H. Bakker, Joseph H. Phillips, Lewis L. Lanier
  • Publication number: 20080171036
    Abstract: TACI receptor antibodies are provided. The TACI antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the TACI antibodies are also provided.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 17, 2008
    Inventors: Anan Chuntharapai, Iqbal Grewal, Kyung Jin Kim, Minhong Yan
  • Publication number: 20080171037
    Abstract: A tumor necrosis factor and lymphotoxin homolog having apoptotic activity, identified as Apo-3 Ligand, is provided. Nucleic acid molecules encoding Apo-3 Ligand, chimeric molecules and antibodies to Apo-3 Ligand are also provided.
    Type: Application
    Filed: August 7, 2007
    Publication date: July 17, 2008
    Inventors: Avi J. Ashkenazi, Scot A. Marsters, Robert Pitti
  • Publication number: 20080171038
    Abstract: The invention is based on the discovery that GM-CSF antagonists can be used for the treatment of Idiopathic Thrombocytopenia Purpura (ITP). Accordingly, the invention provides methods of administering a GM-CSF antagonist, e.g., a GM-CSF antibody, to a patient that has ITP and pharmaceutical compositions comprising such antagonists.
    Type: Application
    Filed: November 8, 2007
    Publication date: July 17, 2008
    Applicant: KaloBios Pharmaceuticals, Inc.
    Inventors: Christopher R. Bebbington, Geoffrey T. Yarranton