Abstract: A heterophasic polypropylene composition comprising (percent by weight referred to the sum of components A) and B)): A) from 80% to 97% of a random copolymer of propylene containing from 0.1 to 4% of 1-hexene derived units; B) from 3-20% of a copolymer of propylene and ethylene having a content of ethylene derived units ranging from 50% to 55% extremes excluded; wherein the heterophasic polypropylene composition is endowed with a Melt Flow Rate: measured according to ISO 1133 (230° C., 5 Kg) ranging from 0.5 to 5 g/10 min; and an intrinsic viscosity (IV) of the fraction soluble in xylene at room temperature ranging from 2.5 to 5.5.

Abstract: There is provided a method for producing an aqueous dispersion of fluorine-containing seed polymer (B) particles, comprising a step for preparing an aqueous dispersion of fluorine-containing polymer (A) particles by polymerizing monomer comprising at least one fluoroolefin in an aqueous dispersion in the presence of a compound (1) represented by the formula: CH2?CHCH2—O—R, wherein R is a hydrocarbon group which may have an oxygen atom, a nitrogen atom and/or a polar group, and (II) a step for seed-polymerizing ethylenically unsaturated monomer with the fluorine-containing polymer (A) particles in the aqueous dispersion of the fluorine-containing polymer (A) particles.

Abstract: A process for making a hyperbranched polyethylene. The process has the steps of (a) reacting a multifunctional acrylate monomer with an ?,?-diene monomer in the presence of a first catalyst to form an alternating acrylate/diene copolymer and (b) reacting the alternating acrylate/diene copolymer with a late transition metal ?-diimine catalyst to form a multi-nuclear initiator for chain walking polymerization of ethylene. There is also a process for forming a multi-nuclear initiator. There is also a hyperbranched polymer.

Abstract: Provided is a dendritic ethylene polymer. The polymer is a dendritic polymer of an ethylene/alpha-olefin-diene copolymer and a vinyl-terminated polyethylene. There is also provided a process for making a dendritic ethylene polymer. The process includes the steps of preparing a dendritic ethylene polymer by reacting ethylene/alpha-olefin-diene copolymer with vinyl-terminated polyethylene in the presence of a radical source. There is also provided a blend and a blown film that include the dendritic ethylene polymer.

Abstract: The present invention provides an electrolyte having high conductivity even under high-temperature low-humidification conditions (e.g. at a temperature of 100 to 120° C. and a humidity of 20 to 50% RH) and thereby makes it possible to realize a higher performance fuel cell. The present invention is a fluoropolymer electrolyte having an equivalent weight (EW) of not less than 250 but not more than 700 and a proton conductivity of not lower than 0.10 S/cm as measured at a temperature of 110° C. and a relative humidity of 50% RH and comprising a COOZ group- or SO3Z group-containing monomer unit, wherein Z represents an alkali metal, an alkaline earth metal, hydrogen atom or NR1R2R3R4 in which R1, R2, R3 and R4 each independently represents an alkyl group containing 1 to 3 carbon atoms or hydrogen atom.

Abstract: A method for preparing a functionalized polymer, the method comprising the steps, of: (i) polymerizing monomers to form a reactive polymer, and (ii) reacting the reactive polymer with a lactone or thiolactone that contains a protected amino group.

Abstract: This invention relates flame retardant compositions containing low molecular weight brominated anionic, chain transfer, vinyl aromatic polymers, hereinafter “ACTVAP”. The compositions can accommodate high bromine content while still exhibiting a low thermally labile bromine content. The compositions have glass transition temperatures, Tg, that are predictive of acceptable melt flows and heat distortion temperatures (HDT) in HIPS and ABS based formulations substrates. The compositions, are suitable flame retardant candidates for use in thermoplastic formulations, e.g. polystyrene and ABS formulations.

Abstract: A method for hydrogenating a polymer containing vinyl aromatic block and the hydrogenated polymer are provided. The method includes providing a polymer having at least one vinyl aromatic block; and hydrogenating the polymer in presence of a heterogeneous catalyst on a support, wherein the heterogeneous catalyst consists essentially of Ru, Zn and B, or Ru, Zn and P.

Abstract: Biodegradable saturated and unsaturated polyester amides (PEA)s made from multiamino acid monomers and methods of making biodegradable saturated and unsaturated PEAs.

Abstract: There is provided a method for production of a high-purity biodegradable polyoxyethylene derivative on an industrial scale using a polyoxyethylene compound containing polylactic acid at the terminal thereof. A biodegradable polyoxyethylene compound represented by formula (1) and a compound represented by formula (I) are caused to react with each other at 60° C. to 120° C. using toluene as a solvent in the presence of sodium acetate to obtain a biodegradable polyoxyethylene derivative represented by formula (2).

Abstract: A method to generate renewable high performance composites and thermoplastics. These materials can be generated from a renewable phenol (syringaldehyde) that can be derived from lignocellulosic biomass. The use of syringaldehyde as a precursor to composites has the potential to reduce the cost and environmental impact of structural materials, while meeting or exceeding the performance of current petroleum derived resins.

Abstract: A method to generate renewable high performance composites and thermoplastics. These materials can be generated from a renewable phenol (syringaldehyde) that can be derived from lignocellulosic biomass. The use of syringaldehyde as a precursor to composites has the potential to reduce the cost and environmental impact of structural materials, while meeting or exceeding the performance of current petroleum derived resins.

Abstract: The invention refers to a thermoplastic polyurethane produced from at least an organic diisocyanate and a compound which is reactive toward isocyanates, wherein the polyurethane comprises the ester of a tricarboxylic acid with at least one alcohol and wherein all acid groups of the tricarboxylic acid are esterified with an alcohol. The invention further refers to a process for producing the respective polyurethane, products comprising this thermoplastic polyurethane and the use of the ester of a tricarboxylic acid as plasticizer in thermoplastic polyurethanes.

Abstract: Disclosed are particles that have an exterior surface coated with a thin polymeric coating, such as a coating that includes a sulfur-containing polymer. Also disclosed are compositions, such as fuel-resistant sealant and coating compositions, which include such particles. Aerospace vehicles having an aperture at least partially sealed with a sealant deposited from such a sealant composition are also disclosed.

Abstract: A process for polymerizing ethylene to produce an ethylene-based polymer including contacting ethylene with a Ziegler-Natta procatalyst, an alkylaluminum cocatalyst and a self limiting agent selected from the group of aliphatic, cycloaliphatic, substituted cycloaliphatic or aromatic esters, anhydrides and amides such that the self limiting agent reduces polymerization rates to no greater than 40% of the polymerization rate in the absence of the self limiting agent at temperatures equal to or greater than 120° C. is provided.

Abstract: A Ziegler-Natta catalyzed ethylene copolymer having a novel composition distribution in which comonomers are incorporated into the high molecular weight polymer molecules and distributed evenly among the entire polyethylene chains, and a method for making the same are provided. The resins having a novel composition distribution have controlled molecular weight distribution which is narrower than conventional ZN-ethylene copolymers but broader than single-site catalyzed ethylene copolymers. The resins having a novel composition distribution exhibit a superior tear strength and impact strength.

Abstract: Provided is a homogeneous catalytic system for use in preparing an ethylene homopolymer or a copolymer of ethylene and ?-olefin, and more particularly a Group 4 transition metal compound in which a cyclopentadienyl derivative 3,4-positions of which are substituted with alkyls and an electron-donating substituent are crosslinked around a Group 4 transition metal. Also provided is a method of preparing an ethylene homopolymer or a copolymer of ethylene and ?-olefin, having high molecular weight, under high-temperature solution polymerization conditions using the catalytic system including such a transition metal compound and a co-catalyst composed of an aluminum compound, a boron compound or a mixture thereof. The catalyst according to present invention has high thermal stability and enables the incorporation of ?-olefin, and is thus effective in preparing an ethylene homopolymer or a copolymer of ethylene and ?-olefin, having various properties, in industrial polymerization processes.

Abstract: Heat aging of the composition comprising melt-fabricable tetrafluoroethylene/perfluoro(alkyl vinyl ether) copolymer, the alkyl containing 1 to 5 carbon atoms and melt flowable polytetrafluoroethylene is effective to cause thermal transformation of the composition in the solid state, which is epitaxial co-crystallization of the polymer components of the composition, and other valuable changes, such as increased continuous use temperature.

Abstract: A method for producing polymer particles includes a suspension step of suspending a first liquid mixture containing an oily olefin monomer, a radical polymerization initiator, and an iodine molecule in a second liquid mixture containing water and an iodide ion to prepare a suspension containing an oil droplet having the first liquid mixture; a synthesis step of synthesizing an iodine compound by allowing a radical generated by cleavage of the radical polymerization initiator to react with the iodine molecule in the oil droplet; and a polymerization step of polymerizing the oily olefin monomer in the oil droplet.

Abstract: A polymer comprising a conducting or semiconducting segment coupled to a polymer segment having an insulating polymer backbone, the polymer further comprising a RAFT functional group coupled to the polymer segment, wherein there is no RAFT functional group in between the conducting or semiconducting segment and the polymer segment.

Abstract: The present invention provides novel 4- and 5-substituted 1,2,3-triazole moieties, with at least one remote polymerizable moiety. The novel mixtures of 4- and 5-substituted regioisomers of 1,2,3-triazole moieties can be separated by chromatography to provide the purified 4- and 5-substituted 1,2,3-triazole moieties. The novel mixtures of 4- and 5-substituted regioisomers of 1,2,3-triazole moieties, and the purified 4- and 5-substituted 1,2,3-triazole moieties, with at least one remote polymerizable moiety, can be converted to a wide variety of useful polymers. The novel compounds of the invention can be employed in a wide variety of compositions. E, Q, Z, X, a, and R1-R4, in the structures below, are defined herein.

Abstract: There is provided a photosensitive resin composition for a microlens. A photosensitive resin composition for a microlens, comprising a component (A), a component (B) and a component (C), wherein the component (A) is a polymer having a maleimide structural unit of Formula (1), the component (B) is a cross-linking agent, and the component (C) is a photosensitizing agent.

Abstract: Polymers and copolymers of polymerizable fluorescent compounds of 7-hydroxycoumarin such as Ethyl-2-methacrylate Umbelliferone-4-acetate are provided. In addition, a sensor comprising this polymer notably for detecting and/or assaying nitrated and organophosphorus compounds, explosives, and toxic compounds is provided.

Abstract: The invention relates to a copolymer of (a) 5 to 40% by weight of isoprenol, (b) 5 to 93% by weight of at least one monoethylenically unsaturated C3 to C8 monocarboxylic acid, an anhydride or salt of same, (c) 2 to 90% by weight of one or more sulfonic acid group-comprising monomers.

Abstract: This invention relates to a transition metal catalyst compound represented by the structure: wherein M is hafnium or zirconium; each X is, independently, selected from the group consisting of hydrocarbyl radicals having from 1 to 20 carbon atoms, hydrides, amides, alkoxides, sulfides, phosphides, halogens, dienes, amines, phosphines, ethers, or a combination thereof; each R1 and R3 are, independently, a C1 to C8 alkyl group; and each R2, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 are, independently, hydrogen, or a substituted or unsubstituted hydrocarbyl group having from 1 to 8 carbon atoms, provided however that at least three of the R10-R14 groups are not hydrogen, compositions thereof and methods of use thereof to prepare polymers.

Abstract: A terpolymer containing propylene, ethylene and an alpha olefins of formula CH2?CHZ wherein Z is an hydrocarbon group having from 2 to 10 carbon atoms wherein: (i) the content of ethylene derived units ranges from 0.5 wt % to 5.0 wt %; (ii) the content of alpha olefin derived units ranges from 1.0 wt % to 5.0 wt %; (iii) the amount (Wt %) of alpha-olefin (C6), the amount (Wt %) of ethylene (C2) and the melting point (Tm) of the terpolymer fulfil the following relation (1) Tm>?(C2+0.8C6)*6+157 (1) (iv) the polydispersity index (PI) ranges from 3 to 8.

Abstract: In a process for producing an elongated polyethylene component, such as a fiber or membrane, polyethylene powder having a molecular weight of at least 3×105 g/mol as determined by ASTM 4020 is dissolved in a solvent to produce an extrudable solution. The solution is then extruded through a die to form an elongated component and at least part of said solvent is removed from the elongated component. The polyethylene powder used in the process is produced by polymerizing ethylene in the presence of a catalyst composition comprising a Group 4 metal complex of a phenolate ether ligand.

Abstract: The present invention is directed to a PLA-graft-lignin polymers and copolymers and methods of making the same. As the lignocellulosic biorefining industry emerges as a viable fuels technology, the availability of the assortment of lignins will also expand. The use of lignins as a copolymer is one area where lignin may be utilized.

Abstract: Curable material comprising silylated polymers containing urethane groups, and use thereof in sealants, adhesives, binders and/or surface modifiers.

Abstract: Aqueous emulsions of epoxy- and organo-substituted, branched organopolysiloxanes are prepared by emulsifying the latter in water with the aid of a dispersing agent. The emulsions are storage stable and are useful in multi-component coating, adhesive, and binder systems.

Abstract: A carbazole polymer including a repeating unit represented by Formula 1 and having excellent one electron oxidation-state stability, wherein, in Formula 1, R1-R4 each independently represents an alkyl group having 1-60 carbon atoms, a haloalkyl group having 1-60 carbon atoms, or similar, Cz represents a divalent group including a carbazole skeleton represented by Formula 2, and Ar represents a divalent aromatic ring or similar; wherein, in Formula 2, R5 represents a hydrogen atom, an alkyl group having 1-60 carbon atoms, or similar, R6-R11 each independently represents a hydrogen atom, a halogen atom, or similar, and m represents an integer 1-10.

Abstract: The present invention relates to a process for the preparation of oxymethylene polymers, the oxymethylene polymers obtained therefrom as well as their use.

Abstract: This invention relates to the composition and processes for preparing thermoset polyimides derived from an asymmetric dianhydride, namely 2,3,3?,4?-benzophenone dianhydride (a-BTDA) with at least one diamine, and a monofunctional terminal endcaps. The monofunctional terminating groups include 4-phenylethynylphthalic anhydride ester-acid derivatives, phenylethyl trimellitic anhydride (PETA) and its ester derivatives as well as 3-phenylethynylaniline. The process of polyimide composite comprises impregnating monomer reactants of dianhydride or its ester-acid derivatives, diamine and with monofunctional reactive endcaps into glass, carbon, quartz or synthetic fibers and fabrics, and then stack up into laminates and subsequently heated to between 150-375° C. either at atmosphere or under pressure to promote the curing and crosslinking of the reactive endcaps to form a network of thermoset polyimides.

Abstract: The present invention relates to certain polymeric compounds based upon a head-to-head (H—H) alkylthio-substituted bithiophene repeating units (e.g., 3,3?-bis(tetradecylthio)-2,2?-bithiophene). Such compounds can exhibit desirable electronic properties and possess processing advantages including solution-processability and/or good stability at ambient conditions.

Abstract: The inventions relate to antiseptic agents and the method for producing thereof and can be used as a broad-spectrum disinfectant in medicine, veterinary medicine, agriculture etc. The method for producing of biocidal polyguanidine that comprises condensation polymerization of hexamethylenediamine with guanine salt additionally uses hydrazine hydrate during the condensation polymerization process, at the following ratio of components, mass %: hexamethylenediamine 20-55 guanidine salt 25-65 hydrazine hydrate the rest. Biocidal polyguanidine obtained by means of the abovementioned method, with the following formula: where n—the number of links A in a single unit of the polymer chain, n=1-3; m—the number of links B in a single unit of the polymer chain, m=2-10; z—the number of single units in the polymer chain, z=4-20; Acid—an acid. The inventions allow obtaining a biocidal polyguanidine with high level of broad-spectrum antimicrobial activity.

Abstract: A n-type ladder copolymer including, a n-type ladder copolymer formed with alternating perylene and pyridine units having chemical structure A having two end groups, where perylene units having at least one solubilizing group attaching at position(s) 1, 6, 7, and/or 12, where R1, R2, R3, and R4 solubilizing group(s) are each independently selected from the group consisting of aryl, alkyl aryl, alkoxy aryl, and aryloxy aryl, and where n repeat units ranging from about 4 to about 400

Abstract: A streptavidin macromolecular adaptor (SAMA) protein may be used for the controlled assembly of nanostructure building blocks and struts including streptavidin:SAMA complexes.

Abstract: It is an object of the present invention to obtain a labeled protein, and specifically, to separate a labeled protein and the same unlabeled protein. There is provided a labeled protein including: a protein to be labeled having a target protein, at least one or more affinity interaction domains for binding to an affinity support, and at least one or more labeling sites; and a labeling reagent binding to at least one of the labeling sites; wherein the affinity of the labeled protein for the affinity support is difference from that of the protein to be labeled for the affinity support.

Abstract: Peptides of general formula (I): R1—Wn—Xm-AA1-AA2-AA3-AA4-Yp—Zq—R2 (I) its stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, a preparation process, cosmetic or pharmaceutical compositions which contain them and their use in the treatment and/or care of the skin, mucous membranes and/or hair and the treatment and/or care of those conditions, disorders and/or diseases which are improved or prevented by Hsp stimulation.

Abstract: Compounds based around tetrapeptide, tripeptide and dipeptide moeties and corresponding peptiod moeties. Related methods and pharmaceutical compositions for use in treatment of cancer, inflammatory diseases, and other disorders.

Abstract: The invention relates to methods and products for modulating glycosylation of proteins. The invention is useful for identifying therapeutic compounds to treat glycosylation-associated disorders such as neurodegeneration, diabetes, including complications of diabetes such as insulin resistance, nephropathy, microvascular damage, and endothelial dysfunction. The invention is also useful for identifying therapeutic compounds to treat de-glycosylation-associated disorders such as ischemic damage and traumatic injury. The invention also relates in part to assays that are useful for identifying and testing candidate compounds for modulating glycosylation of proteins and also relates in part to compounds to treat glycosylation-associated diseases and disorders.

Abstract: Disclosed are methods and compositions relating to plasmin inhibition.

Abstract: The disclosure provides methods of treating X-linked hypophosphatemia, related bone demineralization and renal phosphate wasting disorders in a mammalian subject. The methods comprise administering to the subject an effective amount of a polyarginine peptide.

Abstract: Described herein is an isolated polypeptide which is capable of specifically targeting apoptotic cells undergoing apoptosis and consists of the sequence (I): Cys-X1-Val-Ala-Pro-X2 (I), wherein X1 is an amino acid with polar uncharged side chain and X2 is an amino acid with positive charged side chain. The isolated polypeptide of the present invention may be useful for detecting apoptotic cells, as well as detecting and imaging apoptotic cells in tumor tissue, apoptotic myocardial cells in myocardial infarction tissue, apoptotic nerve cells in stroke tissue, and arteriosclerosis site; the polypeptide is useful for targeted drug delivery thereto.

Abstract: This invention relates to a convenient and improved process for preparation of glatiramer acetate (copolymer-1) of pharmaceutical grade. The process involves polymerizing N-carboxyanhydrides of tyrosine, alanine, y-benzyl glutamate and ?-N-trifluoroacetyllysine in dioxane with diethylamine as initiator to afford protected copolymer-1. Treatment with hydrogen bromide in acetic acid at 35° C. for 3-5 h cleaves benzyl group to produce trifluoroacetyl copolymer-1. The trifluoroacetyl copolymer-1 is washed with an organic solvent to remove reactive benzyl bromide generated during debenzylation. Deprotection with aqueous piperidine, followed by dialysis offers glatiramer acetate (copolymer-1) of Molecular weight 5000-9000 daltons.

Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.

Abstract: The present invention relates to a process for the production of interferon beta, and to an interferon beta composition having a unique glycosylation pattern.

Abstract: This invention provides a method for treating a subject having a tumor and a method for inhibiting angiogenesis in a subject, both comprising administering to the subject an effective amount of a composition of matter comprising the extracellular domain of a Notch receptor protein operably affixed to a half-life-increasing moiety. This invention also provides a composition of matter comprising the extracellular domain of Notch4 receptor protein operably affixed to a half-life-increasing moiety. This invention further provides an article of manufacture. Finally, this invention provides a replicable vector which encodes a polypeptide comprising the extracellular domain of a Notch receptor protein operably affixed to a half-life-increasing moiety, a host vector system which comprises such replicable vector and a method of producing such polypeptide.

Abstract: Anti-NTB-A antibodies and antigen-binding fragments thereof, as well as pharmaceutical compositions comprising such antibodies and antigen-binding fragments are described. Also described are methods of using such antibodies and antigen-binding regions to bind NTB-A and treat diseases, such as hematologic malignancies, which are characterized by expression of NIB-A.

Abstract: Disclosed is an isolated immunoglobulin. Also disclosed are pharmaceutical compositions and medicaments comprising the immunoglobulin, isolated nucleic acid encoding it, vectors, host cells, useful in methods of making it. In some embodiments the immunoglobulin comprises one to twenty-four pharmacologically active chemical moieties conjugated thereto, such as a pharmacologically active polypeptide.