Abstract: A method for optimizing an integrated circuit layout design includes the following steps. A first integrated circuit layout design including a metal line feature having several metal lines and a second integrated circuit layout design including a hole feature having several holes are obtained. A line-end hole feature of the hole feature is selected by piecing the metal line feature with the hole feature. The line-end hole feature is classified into a single hole feature and a redundant hole feature by spacings between the adjacent holes by a computer system.

Abstract: An IC design method includes: receiving a first layout including a first pattern; receiving a second layout including a second pattern, the first pattern separated from the second pattern when overlapping the first layout and the second layout; providing a cut pattern between the first pattern and the second pattern and overlapping the first pattern when overlapping the first layout, the second layout and the cut pattern; and providing a jog extending from the cut pattern to further overlap the first pattern with a length when a spacing between the second pattern and an edge of the cut pattern overlapping the first pattern is lower than a predetermined value, in which a ratio of the length of the jog to the spacing between the second pattern and the edge of the cut pattern overlapping the first pattern is in a range of 1/5 to 1/1.

Abstract: A system and method for managing and composing verification engines and simultaneously applying such compositions to verify properties with design constraints allocates computing resources to verification engines based upon properties to be checked and optionally a user-specified budget. The verification engines are run in order to verify a received register transfer level (RTL) design description of a circuit according to user-specified assertions and constraints received by the system. The particular verification engines to be run are selected from a database of such engines and a run order is designated in sequential, parallel and distributed flows.

Abstract: A measurement target for a semiconductor device is designed. The semiconductor device includes a structure to be measured that has a spectrum response that is comparable to or below system noise level for an optical critical dimension measurement device to be used to measure the structure. The measurement target is designed by obtaining a process window and design rules for the semiconductor device and determining prospective pitches through modeling to identify pitches that produce a spectrum response from the structures that is at least 10 times greater than a system noise level for the optical critical dimension measurement device. A resonance window for each prospective pitch is determined and robustness of the resonance window is determined through modeling. Pitches of the array are selected based on the prospective pitches, resonance windows, and robustness. The target design may accordingly be produced and used to generate a measurement target.

Abstract: A method of manufacture comprises a mask process correction (MPC) and verifying MPC accuracy. MPC may be performed on mask tape-out (MTO) data describing a mask pattern to obtain mask process corrected data. MPC may be performed to address a deviation between the MTO data and a mask to be manufactured. Verification of the MPC may be performed by generating a two-dimensional (2D) contour of mask pattern elements based on the mask process corrected data. When MPC has been verified, the mask process corrected data may be used to manufacture a mask and a semiconductor device.

Abstract: A design application is configured to perform a system-level optimization of a collection of system components. The design application iteratively executes a multi-objective solver to optimize structural and functional relationships between the system components in order to meet global design criteria and generate a system design. The design application initializes the design process by extracting from a knowledge base system templates having taxonomic, structural, or functional attributes relevant to the system design. The design application generates the knowledge base by mining taxonomic, structural, and functional relationships from a corpus of engineering texts.

Abstract: Provided herein are methods and arrangements and related cell-free biomolecular breadboards configured to design, build, implement, debug, and/or test a genetic circuit to be operated in a target environment, by testing in a cell-free system under conditions of the target environment, molecular components of the genetic circuit and/or combinations thereof to select the molecular components and/or combinations thereof of a genetic circuit operative in the target environment.

Abstract: Factors affecting the fragmentation pattern of cell-free DNA (e.g., plasma DNA) and the applications, including those in molecular diagnostics, of the analysis of cell-free DNA fragmentation patterns are described. Various applications can use a property of a fragmentation pattern to determine a proportional contribution of a particular tissue type, to determine a genotype of a particular tissue type (e.g., fetal tissue in a maternal sample or tumor tissue in a sample from a cancer patient), and/or to identify preferred ending positions for a particular tissue type, which may then be used to determine a proportional contribution of a particular tissue type.

Abstract: Techniques for assembly of genetic maps including de novo assembly of distance maps using multiple alignment consensus construction. Multiple map alignment can be performed on a defined bundle of fragment maps corresponding to biomolecule fragments to determine consensus events and corresponding locations. Fragment maps in the bundle can be removed when there is no overhang from the consensus events. When the subset of fragment maps in the bundle is less than a predetermined threshold, one or more additional fragment maps can be added based on fragment signatures, a consensus alignment score, and a pairwise alignment score. Techniques for multiple alignment can include generating a graph with edges and vertices representing each pairwise relation. An ordered set of sets of events best representing a multiple alignment reflecting all pairwise alignments can be generated by repeatedly randomly removing edges and combining vertices to identify a min cut of the graph.

Abstract: Systems for accessing medical imagery from a cloud-based facility using a browser-like application. A first user (e.g., a physician) identifies a first plurality of medical digital information files that are organized in a first storage structure. The first user's requests a set of first digital information views of the identified medical digital information of the first storage structure wherein the plurality of first digital information views are described by a respective first set of logical view attributes that are associated with the files organized in the first storage structure. A second user (e.g., a second physician) requests a second plurality of digital information views of the first storage structure wherein the second plurality of digital information. The system sends the first digital information views to the first user, and sends the second digital information views to the second user.

Abstract: There are provided an information analysis assistance device, an operation method and non-transitory computer readable medium storing an operation program thereof, and an information analysis assistance system. In a case where a date in a table is selected by a first selection method, a screen generation unit sets a first display format to display windows showing the outline of each piece of medical data side by side in a second display region. In a case where an item is selected by a second selection method, the screen generation unit sets a second display format to display a time-series change table showing time-series changes in medical data in the second display region. In a case where a cell is selected by a third selection method, the screen generation unit sets a third display format to display the details of medical data in the second display region.

Abstract: A computer processor may receive medical data including a report and an image. The computer processor may analyze the report using natural language processing to identify a condition and a corresponding criterion. The computer processor may also analyze the image using an image processing model to generate an image analysis. The computer processor may determine whether the report has a potential problem by comparing the image analysis to the criterion.

Abstract: Methods are provided for sharing patient information by way of an online collaboration system. A requesting clinician, through an online networking system, identifies one or more clinicians with whom the requesting clinician wishes to collaborate by sending at least one patient-focused clinical data element. For the clinicians who have been identified as not being authorized to access patient-identifying data, the at least one patient-focused clinical data element is de-identified such that it no longer includes any patient-identifying data. The de-identified patient-focused clinical data element is then communicated to the clinicians not allowed access to the patient-identifying information.

Abstract: What is disclosed is a lab based system for facilitating dating between two or more individuals in which the system matches users by any number of factors but including the factor of what, if any, STD each user is infected with. Users are matched based on STD infection or non infection such that users having the same STD and/or strain of STD are matched together, amongst other potential criteria. In a preferred embodiment, the system further tracks the duration of time that has elapsed and displays that information to each user and/or each user's prospective matches for purposes of, for example, increasing the accuracy of data regarding each user's STD rate and to facilitate ongoing STD testing amongst users.

Abstract: The invention concerns a system for collecting and managing vital data of patients delivered by measuring devices in a healthcare establishment. Such a system comprises a platform that collects and manages said data. The platform cooperates with a server of computerised patient files and with a plurality of communicating devices used by the healthcare staff. The platform comprises repositories of patients and measuring devices in order to control associations or dissociations of devices and patients. The platform generates and transmits requests to the server for relevant and complete updates of computerised patient files. The invention further concerns an administration device that interacts with the platform in order to supervise said measuring devices.

Abstract: A test server includes: a communication unit that communicates with a plurality of communication terminals via a network, the plurality of communication terminals each being connectable to a test device capable of executing a test on the presence or absence of a disease and each being capable of inputting a diagnosis on the presence or absence of the disease, the diagnosis being related to the test and made by a doctor; and a control unit that acquires at least one of a result of the test and the diagnosis as a test information item from each of the plurality of communication terminals via the communication unit, causes a storage unit to store the plurality of acquired test information items therein, performs statistical processing on the plurality of stored test information items, and causes the communication unit to return a result of the statistical processing according to a demand given from each of the communication terminals before the doctor makes a diagnosis.

Abstract: A system for tracking a medical procedure includes a set of macros, a scanning device, and a control unit. Each macro in the set of macros is associated with instructions that execute a tracking step of a medical procedure. The scanning device is controlled by a user during the medical procedure to select a macro from the set of macros. The control unit executes the instructions associated with the selected macro to track the medical procedure.

Abstract: Implementations generally relate to forecasting a support requirement for a health care unit to use in preparing patient support at a target time. In some implementations, a method includes accessing external conditions data for a plurality of different external conditions projected for the location at the target time. The target time and the external conditions data may be provided into a prediction model, which identifies one or more reference times prior to the target time that are predictive of the target time, accesses historical data for the reference times, and outputs the data indicating a support requirement based on the historical data and external conditions data.

Abstract: An assembly and method for tracking implant devices within a sterile field, the assembly comprising a reader that includes a housing structure with a base and a cover, a scanner having a scanner housing, where the scanner housing is at least partially positioned in a cavity provided in the base; and an aperture provided in the cover, where the cover is configured to receive a transparent sterile sheath to at least partially encase the cover.

Abstract: A device and system for providing identification and medical information are disclosed. The device includes a readable code that contains medical biographical information of the subject, a programmable reporter element that is programmed to electronically store at least one particular event relating to the subject, and a signal producing element functionally related to the programmable reporter element. The system includes collecting and storing medical biographical information of a subject, embedding the medical biographical information in a readable code of the device, and scanning the readable code of the device worn by or in the possession of the subject using an appliance to retrieve the medical biographical information of the subject. The medical biographical information allows medical professionals to obtain the subject's medical information in order to provide medical care. Also disclosed is an integrated system for alerting subjects to upcoming events related to their continued care.

Abstract: The present disclosure provides a method for adjudicating reimbursement for allergens between a pharmacist and a reimbursing entity including obtaining at a central control center National Drug Codes (NDC's) for a plurality of allergens, determining by the central control center an Average Wholesale Price (AWP) for each of the allergens associated with each of the NDC's, accessing a third-party database accessible by a pharmacist and determining if any of the NDC's in the central control database are contained within the third-party database, and creating an adjudicating database at the central control center having defined benefits associated with reimbursable entities for each of the NDC's stored in the third-party database and in the central control database, wherein a pharmacist can access this information by accessing a particular NDC in the third-party database to obtain information and enter a claim.

Abstract: A method for at least one of characterizing, diagnosing, and treating a mental health associated condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the mental health associated condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the mental health associated condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

Abstract: A medical information system. In one embodiment, the medical information system includes: a learning engine; a user interface in communication with the learning engine; and a data warehouse in communication with the learning engine, wherein the learning engine will generate a report on a patient in response to patient data. In another embodiment, the data warehouse includes at least one data mart comprising summarized and indexed aggregated data that are pre-calculated and pre-joined. In one embodiment, the learning engine filters requests for aggregated data based on parameters supplied by the user interface. In another embodiment, a user may query medicine treatment statistics in response to diagnostics. In yet another embodiment, some of the plurality of preferences of the physician are predetermined by selection by the physician. In still yet another embodiment, some of the plurality of preferences of the physician are predetermined by actions taken by the physician.

Abstract: The present invention provides a novel semi-supervised learning method based on the combination of the Cox model and the accelerated failure time (AFT) model, each of which is regularized with L1/2 regularization for high-dimensional and low sample size biological data. In this semi-supervised learning framework, the Cox model can classify the “low-risk” or a “high-risk” subgroup though samples as many as possible to improve its predictive accuracy. Meanwhile, the AFT model can estimate the censored data in the subgroup, in which the samples have the same molecular genotype. Combined with L1/2 regularization, some genes can be selected by the Cox model and the AFT model and they are significantly relevant with the cancer.

Abstract: Methods and apparatus to form a biometric based information communication system are described. In some examples, the biometric based information communication system comprises biomedical devices with sensing means, wherein the sensing means produces a biometric result, the sensing means may measure an exposure of the user. In some examples the exposure may be to at least one of an energy source, a biological material or chemical material. In some examples the biometric based information communication system may comprise a user device such as a smart phone paired in communication with the biomedical device. A biometric measurement result may trigger a communication of a biometric based information communication message.

Abstract: A healthcare information system for providing near-real or real-time contact tracing is provided comprising: a position data receiver unit configured to receive position data related to one or more entities associated with a healthcare facility; a contextual profile management unit configured to utilize received position data to generate, maintain or update one or more contextual profiles, each of the one or more contextual profiles corresponding to each of the one or more entities. Devices, systems and methods are provided related to the use of near-real or real-time contact tracing in applications including infection control, developing infection pathways, among others.

Abstract: In part, the disclosure relates to intravascular data collection systems and the software-based visualization and display of intravascular data relating to detected side branches and detected stent struts. Levels of stent malapposition can be defined using a user interface such as a slider, toggle, button, field, or other interface to specify how indicia are displayed relative to detected stent struts. In addition, the disclosure relates to methods to automatically provide a two or three-dimensional visualization suitable for assessing side branch and/or guide wire location during stenting. The method can use one or more a computed side branch location, a branch takeoff angle, one or more stent strut locations, and one or more lumen contours.

Abstract: A system and a method for notifying a user of a current exercise state in real time are disclosed. The system for notifying a user of a current exercise state in real time, according to an embodiment of the present invention, comprises: an exercise program module for generating an exercise program suitable for the user by using information on the user's physical fitness and diseases; an exercise amount measurement module for measuring exercise intensity and exercise time according to the user's exercise; and a feedback module determining whether the user's exercise has satisfied the requirements of the generated exercise program by using the measured exercise intensity and exercise time so as to provide the results to the user as feedback in real time.

Abstract: A system and method for providing updates to medical devices is disclosed. In one example, the medical devices are configured to pull update files in response to the reception of an update message from a server. Once the update files are downloaded by a medical device, the update files can be installed. While the medical device pulls the update files, the medical device can continue with its normal operation. If desired, a user can select which medical devices should be updated, based on any desired factors, such as the physical location of the device, the model of the device, the type of device, and the way the device is being used.

Abstract: Systems to monitor and methods for monitoring the wellness and security of residents in a living community, wherein the living community has a plurality of living units each having a controller and associated sensors. Each controller is configured to receive sensor data from the associated sensors, receive input data from an access device, and send this sensor data and input data to a management platform. The management platform is configured to arrange this data, extrapolate conclusions based on this data, monitor residents in the living community, track progress of residents in the living community, and establish periodic goals for the residents in the living community.

Abstract: Systems, methods, and non-transitory computer-readable storage media for gathering activity data describing a user's activities from one or more activity sensors and using the activity data to predict immune-response to the activity. Predicting immune-response can involve creating, personalizing, and refining immune-response prediction models based on demographic user data, activity data, blood sample data, personal genetic information.

Abstract: A mobile telemedicine unit having a high gain antenna, and mobile modem with a web or client based feature to run over variable bandwidths to connect, stay connected, or auto-reconnect a telemedicine session through a hosted or cloud-based solution. The unit is lightweight, is self-contained with a power source and a wireless signal, and is able to be carried directly to a patient's location or permanently wired in an ambulance. The modem also includes multiple cellular carriers' subscriber identity module cards to improve signal strength. The unit has at least one camera and/or medical diagnostic device that is operated by a medical professional in the patient's presence. This is streamed live over a cellular or satellite signal to a healthcare provider who is able to see, interview and potentially diagnose the patient in real time, remotely.

Abstract: Systems and methods for promoting personal health are provided. Sponsors of a health-related challenge program such as employees can set up goals, select participants, select duration and select prizes or rewards for the participants. The sponsors may also specify one or more acceptable user devices or tracking services that may be used by the participants of the program. The challenge programs may be individual or team based. Users of the present invention can enroll in the programs in any suitable fashion such as through a web interface and/or a health kiosk. A user may activate the enrollment at a health kiosk. The user may associate and/or dissociate tracking devices and/or services with a user account. Data collected at the health kiosk and/or from the associated tracking devices or services may be used to determine the performance of users or groups of users in the challenge programs.

Abstract: Systems, methods, and non-transitory computer-readable storage media for constructing a clinically-derived and personalized blood cell mobilization prediction models, enhancing the understanding of a blood tests by excluding the contemporary effect of the contemporary activity from the contemporary blood sample data, optimizing a vaccine by maximizing a concentration of a collection of immune cells which interact with the collection of antigens present in the vaccine can be prescribed, and enhancing the reliability of activity data by accounting for inconsistencies, gaps in data, etc. that is collected from telemetric devices.

Abstract: The present invention relates to an apparatus and method for providing a virtual treatment experience which can make a user to understand the necessity for treatment and learn how to counteract side effects of the treatment.

Abstract: A pharmaceutical order filling system receives pharmaceutical orders and uses an automated dispensing device to dispense pharmaceuticals into containers. The automated dispensing device is configured with a filling cabinet that stores and dispenses measured quantities of pharmaceuticals and is further configured to stage measured quantities of pharmaceuticals in buffer tubes to enable efficient fulfillment of the pharmaceutical orders. Containers may be disposed on a pallet which may be moved within an automated dispensing device to place the containers under buffer tubes to receive measured quantities of pharmaceuticals from the buffer tubes into appropriate containers in an efficient manner.

Abstract: A logging system (200) and a method of registering data for enabling monitoring of intake of a product by a user according to an intake plan are provided. The logging system (200) comprises a dispensing device (220) for dispensing the product to the user who operates the dispensing device by manual interaction and a logging device (240). The dispensing device has identification data (ID) which identifies the device itself or identifies the product dispensed by the device. The dispensing device and the logging device are able to communicate via body coupled communication. When the dispensing device and the logging device are both in the close vicinity of the body of the user (110) who carries the logging device during said manual interaction, the identification data is transmitted via body coupled communication to the logging device which subsequently stores the received data in a data storage.

Abstract: A glycemic control system includes a physician processor, remote processor, and a portable telephone having a data input mechanism, a display, and an internal processor for bi-directional communication with the physician's processor and the remote processor. A patient inputs data to the internal processor responsive to input from the physician's processor and then transmits the information to the remote processor where an optimized number of units to be administered is sent back and displayed on the portable telephone.

Abstract: Systems and methods are provided for facilitating the delivery of chronic disease prevention programs. The method includes: receiving an electronic record for a participant; interrogating a database of CBOs and selecting a particular CBO to provide a chronic disease prevention program for the participant; enrolling the participant in the program; updating the electronic record as the participant progresses through the program; submitting a claim to a health plan administrator upon completion of the program by the participant; and transmitting payment to the selected CBO.

Abstract: Systems and methods for providing graphical information regarding one or more patients' medical information are described. The graphical information can be used in various methods of graphical comparison, including graphical diagnoses, graphical comparison between patients, over time with a single patient, and/or over time with and/or between multiple patients. The graphical information can be used in place of and/or in conjunction with existing methods and systems for conveying medical information, including one or more textual methods and systems. The graphical information is provided electronically to any electronic or computer device or is provided in hard copy, such as a part of a patient's chart. The use of graphical patient medical information permits rapid and improved conveyance of information, and improves recognition and understanding of the most relevant medical information.

Abstract: Systems and methods are provided for matching a candidate for a chronic disease prevention program with a best fit program provider. The method includes determining a respective ideal profile for each of a plurality of program providers; segmenting a heterogeneous patient population into a plurality of homogeneous sub-groups; collecting patient data for the candidate; assigning the candidate to a first one of the homogeneous sub-groups based on the patient data; comparing the first sub-group to a plurality of the respective ideal profiles; and determining a best fit program provider based on comparing the first sub-group to a plurality of the respective ideal profiles.

Abstract: Systems and methods for obtaining an electronic informed consent from a patient/trial subject for a medical procedure/clinical trial recruitment. A search query may be received from the patient/trial subject. After transmitting a search result, a registration request may be received from the patient/trial subject to participate in one or more medical procedure/clinical trial. At least one unique code is transmitted to the patient/trial subject. Each code may be specific to the medical practitioner conducting the medical procedure/clinical trial. The code enables the patient/trial subject to access a multimedia file corresponding to the medical practitioner. Input on the multimedia file is received and informed consent is invoked in response to receipt of the input. An electronic consent on an informed consent form is then received.

Abstract: The disclosed subject matter relates to systems, methods, and media for media session concurrency management with recurring license renewals. More particularly, the disclosed subject matter relates to using recurring license renewals for concurrent playback detection and concurrency limit enforcement for video delivery services and managing server resources for handling such recurring license renewals.

Abstract: Software revalidation or invalidation. In one example embodiment, one or more non-transitory computer-readable media may store one or more programs that cause one or more processors to execute a method for software revalidation or invalidation that may include newly collecting machine configuration information from a machine on which a software application has previously been installed and activated and applying, at the machine, activation rules to the newly-collected machine configuration information from the machine to determine whether a product key remains valid for the newly-collected machine configuration information. In response to determining that the product key remains valid for the newly-collected machine configuration information, the method may include revalidating, at the machine, the software application to authorize continued access to the software application.

Abstract: Method for processing data, in which a Petri net is encoded, written into a memory and read and executed by at least one instance, wherein transitions of the Petri net read from at least one tape and/or write on at least one tape symbols or symbol strings, with the aid of at least one head. In an alternative, data-processing, co-operating nets are composed, the composition result is encoded, written into a memory and read and executed from the memory by at least one instance. In doing this, components can have cryptological functions. The data-processing nets can receive and process second data from a cryptological function which is executed in a protected manner. The invention enables processing of data which prevents semantic analysis of laid-open, possibly few processing steps and which can produce a linkage of the processing steps with a hardware which is difficult to isolate.

Abstract: System, method and apparatus for securely distributing content via an encrypted file wherein a Publisher Key (PK) associated with an authorized publisher enables presentation of the content by the authorized user via a Limited Capability Viewer (LCV), the LCV lacking the capability to forward, print, copy or otherwise disseminate the content to be presented unless available advanced permissions are granted to the authorized user.

Abstract: An electric vehicle supply equipment (EVSE) receives, from an electric vehicle (EV) connected to the EVSE, one or more electric vehicle (EV) operator-specific parameters that are specific to an EV operator, where the one or more EV operator-specific parameters affect charging service for the EV at the EVSE, and where the one or more EV operator-specific parameters are received automatically as a result of the EV being connected to the EVSE. The EVSE applies the one or more EV operator-specific parameters.

Abstract: An input device for an electronic system includes: an input surface, configured to provide an interface for determining positional information for an input object in a sensing region of the input device; a biometric sensor, configured to determine biometric information about a user; and a processing system, configured to: in response to placement of a valid biometric object on the biometric sensor, enable access to a secure object of the electronic system while the valid biometric object is maintained on the biometric sensor; and disable access to the secure object of the electronic system in response to removal of the valid biometric object from the biometric sensor.

Abstract: A self-powered, portable fingerprint-activated apparatus for audibly outputting personal data includes a memory, a fingerprint scanner, circuitry, and a self-powered power cell. The memory is configured to pre-store the personal data including a fingerprint of a subject. The circuitry is configured to compare a scanned fingerprint from the scanner with the pre-stored fingerprint of the subject and to audibly output the pre-stored personal data upon authenticating the scanned fingerprint of the subject. The self-powered power cell is configured to power the circuitry.

Abstract: Methods and apparatus to form a biometric based information communication system are described. In some examples, the biometric based information communication system comprises biomedical devices with sensing means, wherein the sensing means produces a biometric result where the result may comprise results which are unique to the user and support identification. In other examples, biomedical devices which are embedded or otherwise connected to a user may have function specifically included to provide stored identification data unique to the user which may be communicated under specified conditions. A identification result may trigger a communication of a biometric based information communication message.