Patents Issued in May 31, 2018
  • Publication number: 20180147309
    Abstract: A sterilization system includes a first chamber, a second chamber, a sterilization module, and a pump assembly. The first chamber includes a first venting valve. The first chamber is configured to receive a first medical device. The first chamber is further operable to sterilize the first medical device. The first sterilization module is operable to dispense sterilant into the first chamber. The pump assembly is in fluid communication with the first chamber and the second chamber. The pump assembly is operable to selectively and repeatedly transfer at least some of the sterilant from the first chamber to the second chamber. The pump assembly is further operable to selectively and repeatedly transfer at least some of the sterilant from the second chamber to the first chamber.
    Type: Application
    Filed: June 9, 2017
    Publication date: May 31, 2018
    Inventor: Navid Omidbakhsh
  • Publication number: 20180147310
    Abstract: A modular medical instrument sterilization container and related methods are disclosed. The container includes a base and a plurality of sidewalls, each being substantially planar and having a consistently repeated cross-section. A plurality of corner posts having a uniform, consistent cross-section is connected between the plurality of sidewalls. A plurality of bottom edge rails having a uniform, consistent cross-section is connected between a sidewall and the base. A plurality of top edge rails having a uniform, consistent cross-section is connected to the sidewall. A plurality of junction connectors are connected between one of the plurality of corner posts and at least one of: two of the bottom edge rails and two of the top edge rails.
    Type: Application
    Filed: January 23, 2018
    Publication date: May 31, 2018
    Inventors: Robert Cushion, George P. Hannafin
  • Publication number: 20180147311
    Abstract: Emission of a scented substance, which is mixed with a tracer substance, is controlled based on an amount of the tracer substance sensed during the emission of the scented substance. The scented substance can be mixed with the tracer substance in a known defined ratio. When the mixture of the scented substance and tracer substance is being emitted by a device, a substance sensor component can sense the amount of the tracer substance being emitted. An emission management component can control the emission of the mixture of substances based on the amount of the tracer substance detected to facilitate controlling the amount of the scented substance being emitted. The emission management component also can control emission of the scented substance in a defined area based on the tracer substance and environmental conditions in the defined area. The tracer substance can be safe, colorless, and/or odorless with respect to people.
    Type: Application
    Filed: November 30, 2016
    Publication date: May 31, 2018
    Inventor: Peter G. Hartwell
  • Publication number: 20180147312
    Abstract: A ventilation duct to eradicate indoor odor and microbes includes an air purifying enclosure, a hydroxyl generator, a centrifugal duct fan, an air directing duct. The air purification process is completed through the ventilation duct to eradicate indoor odor as the air purifying enclosure, the hydroxyl generator, the centrifugal duct fan, and the air directing duct are in fluid communication with each other. The hydroxyl generator disinfects and converts a flow of contaminant air into a flow of purified air after the flow of contaminant air is drawn into the air purifying enclosure. The flow of purified air is then respectively discharged from the air purifying enclosure to the centrifugal duct fan and the air directing duct, before exiting the ventilation duct.
    Type: Application
    Filed: November 30, 2017
    Publication date: May 31, 2018
    Inventor: Douglas Lee Ryerson
  • Publication number: 20180147313
    Abstract: A photocatalytic honeycomb assembly and a photocatalytic purification apparatus, which can maximally increase a contact area between polluted air and a photocatalyst while maximally ensuring that the surface of the photocatalyst receives sufficient irradiation of ultraviolet light, and can also make the flow resistance to air flowing in a channel meet requirements in the field of ventilation systems which have high requirements on flow resistance. The photocatalytic honeycomb assembly is formed of one or more photocatalytic honeycomb cores and a photocatalytic honeycomb assembly housing. The one or more photocatalytic honeycomb cores are arranged in a honeycomb form. The photocatalytic honeycomb core is formed of three or more basic core units and a light guide member that is Y-shaped in an end view.
    Type: Application
    Filed: November 9, 2016
    Publication date: May 31, 2018
    Applicants: COMMERCIAL AIRCRAFT CORPORATION OF CHINA, LTD., SHANGHAI AIRCRAFT DESIGN AND RESEARCH INSTITUTE OF COMMERCIAL AIRCRAFT CORPORATION OF CHINA
    Inventors: Zhan Cheng, Qiaosheng Shi, Wei Kuang, Cun Zhang, Zhongyuan Ren, Guangwen Wang, Xizhong Jian, Chengyun WU, Xuede Sun, Na Jiang, Zhi Yang
  • Publication number: 20180147314
    Abstract: A system for disinfecting a fluid, including: a flow cell including one or more inlet ports and one or more outlet ports, wherein the flow cell is configured to communicate a fluid containing a biological contaminant from the one or more inlet ports to the one or more outlet portions through an interior portion thereof; and one or more point radiation sources disposed about the flow cell, wherein the one or more point radiation sources are operable for delivering radiation to the biological contaminant; wherein an interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources; and wherein the interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources such that a radiation intensity is uniform throughout the interior portion of the flow cell. In one exemplary embodiment, the flow cell is an integrating sphere.
    Type: Application
    Filed: January 8, 2018
    Publication date: May 31, 2018
    Inventors: Edward Brittain Stokes, Jennifer Godwin Pagan, Thomas Andrew Schmedake
  • Publication number: 20180147315
    Abstract: The invention relates to a wound dressing material with a biocompatible monofilament fabric which forms a contact face on a wound and is designed as a carrier layer on which a cover element is applied and is firmly connected at least in parts to the carrier layer. The invention further relates to a method for producing such a wound dressing material, in which method a biocompatible monofilament fabric is formed as a first web material, a cover element is formed as a second web material, and the first web material and the second web material are brought together, wherein the biocompatible monofilament fabric and the cover element are firmly connected to each other, in particular welded, and the wound dressing material is produced as a band.
    Type: Application
    Filed: July 9, 2015
    Publication date: May 31, 2018
    Applicant: Sefar AG
    Inventors: Gerd GERDES, Jeremie WEBER, Alexander HAUSSER
  • Publication number: 20180147316
    Abstract: Described herein is the synthesis of adhesive from simple adhesive coacervates and their uses thereof. The adhesives are composed of (a) a polyanion in the absence of a polycation, wherein the polyanion comprises at least one crosslinking group capable of covalently crosslinking with itself, and (b) a sufficient amount of a complimentary multivalent cation or multivalent anion to produce the simple coacervate. The adhesives have numerous medical and non-medical applications.
    Type: Application
    Filed: March 11, 2016
    Publication date: May 31, 2018
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventor: Russell J. STEWART
  • Publication number: 20180147317
    Abstract: Embolic particles are described. The particles are reaction products of a prepolymer solution including at least one polyether macromer and an appropriate monomer.
    Type: Application
    Filed: January 23, 2018
    Publication date: May 31, 2018
    Inventors: Gregory M. Cruise, Steve Plotkin, Xinping Wu
  • Publication number: 20180147318
    Abstract: Biocompatible copolymers and thermo-responsive hydrogels formed from the copolymers are disclosed. The biocompatible copolymers include monomers comprising polysaccharides or derivatives thereof, therapeutic agents or derivatives thereof, and thermo-responsive monomers and are cross-linked with an acrylamide-containing crosslinker. The hydrogels are used as implant materials to treat or prevent joint damage or osteoarthritis in a subject.
    Type: Application
    Filed: May 18, 2016
    Publication date: May 31, 2018
    Inventor: Juana Mendenhall
  • Publication number: 20180147319
    Abstract: Devices prepared from polyetherimide resins are disclosed. In one aspect, the article can be a medical device configured for use in a body.
    Type: Application
    Filed: May 19, 2016
    Publication date: May 31, 2018
    Applicant: SABIC Global Technologies B.V.
    Inventors: Lynn COLUCCI-MIZENKO, Andrew KUGLER
  • Publication number: 20180147320
    Abstract: The present invention relates to an injectable homogeneous aqueous solution of chitosan containing, in a physiologically acceptable medium, between 0.1 and 4.5% by weight of a chitosan having a degree of acetylation less than 20% and a weight average molecular mass of between 100,000 and 1,500,000 g/mol, said solution having a pH greater than or equal to 6.2, and advantageously between 6.2 and 7.2, said solution not containing any chitosan having a degree of acetylation greater than 20%, said solution being liquid and homogeneous at ambient temperature.
    Type: Application
    Filed: April 22, 2016
    Publication date: May 31, 2018
    Inventors: Alexandre Guerry, Frédéric Bertaina
  • Publication number: 20180147321
    Abstract: The invention relates to the field of tissue engineering and regenerative medicine, and particularly to a three-dimensional biomimetic tissue scaffold that exploits the use of three-dimensional print technology. Surface energy is controlled by precisely placing polymers with differing surface chemistry, and using surface texture and bulk composition to pattern absorbable and non-absorbable polymers for the purpose of promoting functional healing in a mammalian body.
    Type: Application
    Filed: November 10, 2017
    Publication date: May 31, 2018
    Inventors: Lukas Bluecher, Michael Milbocker
  • Publication number: 20180147322
    Abstract: Disclosed are an implantable medical device, a preparation method thereof and an implantable medical device preform for the preparation of the implantable medical device. The implantable medical device comprises a metal basal body (21) and a polymer film layer (22) covering the surface of the metal basal body (21) and preventing endothelium growth and covering, and also comprises a transitional body (23), which is located between the metal basal body (21) and the polymer film layer (22) and covers at least part of the surface of the metal basal body (21), wherein the transitional body (23) is connected to the polymer film layer (22) and the metal basal body (21). By arranging the transitional body (23) to be connected to the polymer film layer (22) and the metal basal body (21), the polymer film layer (22) will not easily fall off when being implanted into a human body.
    Type: Application
    Filed: May 17, 2016
    Publication date: May 31, 2018
    Applicant: Lifetech Scientific (Shenzhen) Co., Ltd.
    Inventors: Zuqiang Qi, Xiaole Jia, Zhou Chen
  • Publication number: 20180147323
    Abstract: A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification is disclosed. The method includes preconditioning, pre-stressing, or pre-damaging fixed bioprosthetic tissue in a manner that mimics the damage associated with post-implant use, while, and/or subsequently applying a calcification mitigant such as a capping agent or a linking agent to the damaged tissue. The capping agent suppresses the formation of binding sites in the tissue that are exposed or generated by the damage process (service stress) and otherwise would, upon implant, attract calcium, phosphate, immunogenic factors, or other precursors to calcification. The linking agent will act as an elastic reinforcement or shock-absorbing spring element in the tissue structure at the site of damage from the pre-stressing.
    Type: Application
    Filed: January 24, 2018
    Publication date: May 31, 2018
    Inventors: James A. Davidson, Jeffrey S. Dove, Darin P. Dobler
  • Publication number: 20180147324
    Abstract: The present invention relates to a three-dimensional cell culture system which can be used to culture a variety of different cells (Human mesenchymal stem cells, Human fibroblast, Keratinocytes, fibroblast differentiated form mesenchymal stem cells in vitro and keratinocytes differentiated form mesenchymal stem cells in vitro) in vitro for continued periods of time. In the present invention, mesenchymal stem cells (MSCs) derived from bone marrow or umbilical cord are inoculated and grown on a pre-established scaffold or matrix made up of chitosan and gelatin. The developed tissue constructs contain cells, growth factors, cytokines and other regulatory factors secreted by cells. The developed bioengineered tissue constructs provide the support, growth factors and essential cytokines for wound healing. Developed tissue construct useful in the treatment of burns wound, diabetic foot ulcer wound and type of chronic skin wounds. It is helpful in healing and regeneration of skin tissue.
    Type: Application
    Filed: April 12, 2017
    Publication date: May 31, 2018
    Inventors: Rajan Datt, Siddharth Pandey, Pallavi Shrivastava, Supriya Srivastava
  • Publication number: 20180147325
    Abstract: An ostomy bag insert (104) comprising a polyacrylate superabsorbent (300) and a powdered zeolite (301). The ostomy bag insert is configured to absorb fluids excreted by the body and to control odours resultant from the excreted matter within the ostomy bag (100). The present zeolite exhibits enhanced odour control.
    Type: Application
    Filed: January 29, 2018
    Publication date: May 31, 2018
    Inventor: Stewart Lee
  • Publication number: 20180147326
    Abstract: Provided herein are compositions comprising: (a) a polymeric catechol binder, such as: polymeric dopamine, polymeric norepinephrine, polymeric epinephrine; polymeric pyrogallol, polymeric tannic acid, polymeric hydroxyhydroquinone, polymeric catechin, polymeric epigallocatechin etc.; and (b) a hydrophilic polymer, methods for using the compositions to coat a substrate, and methods for making the compositions. In particular, the substrate may form part of an apparatus on which it would be beneficial to limit biofouling and/or protein binding.
    Type: Application
    Filed: May 26, 2016
    Publication date: May 31, 2018
    Applicant: The University of British Columbia
    Inventors: Jayachandran N. Kizhakkedathu, Dirk Lange, Joey Lo, Yan Mei, Kai Yu
  • Publication number: 20180147327
    Abstract: A molded article consisting of an organic compound, preferably cellulose fibers having a glass transition point above 200 C and melt blended with thermoplastic polymers of different melt temperatures, whereby, a 3 or 4 Dimensional printer that may consist of an additional 5 or 6 axis, has cellulose fiber particles that are layered and compressible in a semi solid state. These layers having non oriented cellulose fiber particles will help produce a buoyant molded article with a surface texture that can absorb moisture and attract gases for coatings.
    Type: Application
    Filed: March 3, 2017
    Publication date: May 31, 2018
    Inventor: Robert C. Joyce
  • Publication number: 20180147328
    Abstract: An endoscopic surgical device having a windowed blade case featuring an interior surface that is black or dark plastic, provides improved feasibility and ease of use.
    Type: Application
    Filed: January 18, 2018
    Publication date: May 31, 2018
    Inventors: Douglas Keller, Shannon Vaughn
  • Publication number: 20180147329
    Abstract: A digitally controlled aspirator is provided with a processor that allows the user to select operating conditions including one or more default settings. The processor further includes sensors for sensing operational and environmental conditions and adjusts the operation of the aspirator to reflect the sensed conditions.
    Type: Application
    Filed: November 30, 2017
    Publication date: May 31, 2018
    Inventors: Leslie H. Sherman, George Beck, Richard Goetzl, Dorian LeCroy
  • Publication number: 20180147330
    Abstract: The present invention discloses a multifunctional negative pressure drainage system switchable between various modes, including continuous negative pressure, intermittent negative pressure, rinsing, drug administration, and drug administration loop, including a medical wound dressing, a waste fluid bottle, a vacuum pump, a draining tube A, an airway A, a draining tube B, a peristaltic pump, a draining tube C, an infusion bottle, a draining tube E, a control valve A, a control valve B, and a control valve F. The medical wound dressing, the draining tube B, the peristaltic pump, the draining tube C, and the infusion bottle are connected in turn. The medical wound dressing, the draining tube A, the waste fluid bottle, the airway A, and the vacuum pump are connected in turn. The draining tube E is connected between the draining tube C and the draining tube A. The control valve A is disposed on the draining tube A.
    Type: Application
    Filed: July 30, 2015
    Publication date: May 31, 2018
    Applicant: Guangzhoa Sun-Shing Biotech Co., Ltd.
    Inventors: YUN PENG, XI FENG YANG, CHEN GUANG ZENG
  • Publication number: 20180147331
    Abstract: The present invention provides an electric breast pump. The electric breast pump includes a conduit module, a suction module and a host. The conduit module includes a connector, a first conduit and a second conduit. The connector has an electric contact and an opening hole, and the connector is further disposed with a protrusion at the side of the connector on which the opening hole is formed. The first end of the first conduit connects to the electric contact. The first end of the second conduit connects to the opening hole. The suction module has an adapter body coupled with the connector to connect the suction module and the conduit module. The host connects to the second end of the first conduit and the second end of the second conduit. The host controls the suction module via the conduit module to extract and collect milk when the suction module contacts mother's breast.
    Type: Application
    Filed: June 14, 2017
    Publication date: May 31, 2018
    Inventor: Kuei-Chen LIU
  • Publication number: 20180147332
    Abstract: The invention relates to a system for ventricular circulatory support, comprising a device (2) for applying a magnetic field to a magnetised body fluid (1), particularly blood, in a region of a vessel (3), particularly a blood vessel. The system also comprises a control device designed to actuate said device (2) for applying a magnetic field such that, in the region of the vessel (3), a magnetically-induced force acts on the magnetised body fluid (1) in the longitudinal direction of said vessel (3).
    Type: Application
    Filed: March 23, 2016
    Publication date: May 31, 2018
    Inventors: Stephan Ensminger, Tim Kaufmann
  • Publication number: 20180147333
    Abstract: A method of controlling an implantable blood pump of a living patient. The method includes receiving one or more pump signals indicating at least one from the group consisting of a motor speed of the blood pump, power supplied to the blood pump, and differential pressure exerted by the blood pump. One or more medication signals is received indicating whether the patient has taken a medication. The flow rate of blood based on a combination of the one or more pump signals and the medication signals is determined. At least one from the group consisting of increasing and decreasing power is supplied to the pump in response to the determined flow rate.
    Type: Application
    Filed: November 29, 2017
    Publication date: May 31, 2018
    Inventor: John RUDSER
  • Publication number: 20180147334
    Abstract: Devices, systems and methods for establishing a blood flow conduit between a chamber in a heart of a patient and a remote location. A blood inflow cannula having an outer surface and proximal and distal end portions. The distal end portion is configured for insertion into the chamber of the heart. First and second anchor elements have respective maximum width dimensions extending outwardly from the outer surface of the cannula. The first anchor element is positioned more distally than the second anchor element defining a tissue receiving space therebetween. The maximum width dimension of the first anchor element may be larger than the maximum width dimension of the second anchor element in use. The first anchor element is configured to be positioned inside the heart chamber and the second anchor element is configured to be positioned outside the heart chamber with heart tissue held in the tissue receiving space therebetween.
    Type: Application
    Filed: January 23, 2018
    Publication date: May 31, 2018
    Inventors: Oliver MARSEILLE, Wolfgang KERKHOFFS
  • Publication number: 20180147335
    Abstract: An extracorporeal blood treatment apparatus is provided comprising a filtration unit (2) connected to a blood circuit (17) and to a dialysate circuit (32); a control unit (12) is configured for calculating a sodium concentration value for the blood; the estimation of the sodium concentration includes the sub-step of calculating the sodium concentration value as an algebraic sum of a main contribution term based on the isoconductive sodium concentrate and of an offset contribution term based on a concentration of at least a substance in the dialysis fluid chosen in the group including bicarbonate, potassium, acetate, lactate, citrate, magnesium, calcium, sulphate and phosphate.
    Type: Application
    Filed: May 23, 2016
    Publication date: May 31, 2018
    Inventor: Anders Nilsson
  • Publication number: 20180147336
    Abstract: Provided are nanoporous silicon nitride membranes and methods of making such membranes. The membranes can be part of a monolithic structure or free-standing. The membranes can be made by transfer of the nanoporous structure of a nanoporous silicon or silicon oxide film by, for example, reactive ion etching. The membranes can be used in, for example, filtration applications, hemodialysis applications, hemodialysis devices, laboratory separation devices, multi-well cell culture devices, electronic biosensors, optical biosensors, active pre-concentration filters for microfluidic devices.
    Type: Application
    Filed: October 13, 2017
    Publication date: May 31, 2018
    Inventors: Christopher C. Striemer, Jon-Paul DesOrmeaux
  • Publication number: 20180147337
    Abstract: A heating apparatus for heating a dialysis liquid includes a receiving section for receiving a heating bag through which dialysis liquid to be heated can flow, and a sensor system for determining or monitoring the deformation or the position of the heating bag in the receiving section of the heating apparatus or both. A dialysis liquid tube set, a set, a medical apparatus and a method are also described.
    Type: Application
    Filed: January 25, 2018
    Publication date: May 31, 2018
    Inventors: Nicolas Beisser, Stefan Oesterreich
  • Publication number: 20180147338
    Abstract: The present disclosure relates to dialysis devices. In some embodiments, a dialysis device may include a disposable housing having a storage chamber in fluid communication with a dialysate flow path. Also included may be a controller, an interface capable of operably coupling the controller and the disposable housing, a fluid displacement structure, a pump configured to actuate a deformable diaphragm, and a pressure sensor to trigger the reversal of the pump. The flow path may be fluidly sealed from the controller and the interface.
    Type: Application
    Filed: November 30, 2017
    Publication date: May 31, 2018
    Applicant: TEMASEK POLYTECHNIC
    Inventors: Christian Gert Bluchel, Liutong Lin
  • Publication number: 20180147339
    Abstract: The invention relates to an arrangement having a blood pump and a gas exchanger for extracorporeal membrane oxygenation. According to the invention, the blood pump is designed as a pulsatile blood pump and is arranged with the gas exchanger in the same housing. The pulsatile blood pump and the gas exchanger are preferably connected to the same gas source so that the blood pump can be pneumatically driven. The novel ECMO system has a simple design, is flexible, and in particular can be used directly on the patient.
    Type: Application
    Filed: January 26, 2018
    Publication date: May 31, 2018
    Inventor: Oliver Marseille
  • Publication number: 20180147340
    Abstract: A system for separating and transferring phases of a fluid through centrifugation including a centrifuge having a rotating axis, a platform that is rotatable around the rotating axis; and a device for separating and transferring the phases of the fluid. The device includes a separating container and a receiving container connected to the separating container through a connecting channel. A passive valve system is provided in the connecting channel. The device is mounted in the centrifuge platform such that in use at a first predefined range of centrifugal force a fluid provided within the separating container is separated into phases and at a second predefined range of centrifugal force the valve system opens, thereby transferring a phase of the fluid from the separating container to the receiving container.
    Type: Application
    Filed: April 28, 2016
    Publication date: May 31, 2018
    Inventors: Francisco VIDAL FAYOS, Nuria NOGUERA FERRER, Emiliano TOLOSA GONZÁLEZ
  • Publication number: 20180147341
    Abstract: This tray includes spaced apart openings arranged in parallel rows, intended to receive the bodies of the elongated objects, and projections making it possible to place the flanges of the elongated objects inserted in these openings in a determined angular position on the tray when the bodies of these elongated objects are engaged in these openings. According to the invention: said projections are arranged so as to place the length of said flanges in a determined angular position with respect to the rows of openings, and the openings of a first row of openings are arranged with respect to a second row of openings adjacent to said first row, such that after installation of the elongated objects on the tray, the flanges of the objects inserted in the openings of said the first row imbricates with the flanges of the objects inserted in the openings of said second row, i.e.
    Type: Application
    Filed: January 29, 2018
    Publication date: May 31, 2018
    Inventors: Samuel Gagnieux, Thomas Dubois, Franck Carrel, Nicolas Eon, Aurelie Allanic
  • Publication number: 20180147342
    Abstract: A fluid delivery system comprises: a control interface and multiple unique loading guides. The control interface of the fluid delivery system is configured to accept a fluid pump assembly. The multiple loading guides are retractable from the fluid delivery system to retain and control movement of a facing of the fluid pump assembly to contact the control interface on the facing of the fluid delivery system. In one configuration, the control interface is disposed in a cavity of the fluid delivery system; the multiple loading guides are disposed at locations in proximity to the cavity. The multiple loading guides can be configured to slidably retract in unison to support substantially orthogonal insertion of the fluid pump assembly into the cavity of the fluid delivery system.
    Type: Application
    Filed: December 22, 2017
    Publication date: May 31, 2018
    Inventors: Jesse E. Ambrosina, Benjamin G. Powers
  • Publication number: 20180147343
    Abstract: Implantable devices for drug delivery in response to detected biometric parameters associated with an opioid drug overdose and associated systems and methods are disclosed herein. An implantable drug delivery device configured in accordance with some embodiments of the present technology can include a housing and a reservoir configured to contain a drug for treatment of the opioid overdose. The implantable drug delivery device can also include one or more sensors each configured to detect the biometric parameters associated with the overdose. The implantable drug delivery device can further include a controller configured to receive signals related to the biometric parameter, determine whether the overdose occurred based on the signals, and, if the overdose is detected, cause the drug to be delivered to the patient.
    Type: Application
    Filed: June 13, 2017
    Publication date: May 31, 2018
    Inventor: Geoffrey Louis Tyson
  • Publication number: 20180147344
    Abstract: The control device is used to control delivery of fluids from a multi-fluid delivery system during a medical injection procedure. The fluid delivery system includes an injector used to deliver injection fluids to a patient. The control device is operatively associated with the injector for controlling discrete flow rates of injection fluids delivered to the patient. The control device includes first and second actuators associated with the manual control device, and an electronic substrate disposed within the manual control device and having a conductive pattern. The first actuator is operatively associated with the conductive pattern. The conductive pattern includes a plurality of predetermined digital values corresponding to discrete flow rates of injection fluids to be delivered by the injector.
    Type: Application
    Filed: January 8, 2018
    Publication date: May 31, 2018
    Inventors: RALPH H. SCHRIVER, THOMAS P. JOYCE, MICHAEL RILEY, WILLIAM D. BARLOW
  • Publication number: 20180147345
    Abstract: A joining unit (400) for controlling a connection between an infusion pump (200) and a cannula (310) is described. The joining unit has a connection detector for detecting whether an infusion pump is connected to a cannula. The joining unit further has a wireless transmitter for transmitting to the infusion pump a connection indication in response to detecting by the connection detector that the infusion pump is connected to the cannula.
    Type: Application
    Filed: June 2, 2016
    Publication date: May 31, 2018
    Inventors: Katriina Petäinen, Matti Naskali
  • Publication number: 20180147346
    Abstract: An infusion system for transporting fluid into a patient and a method for integrity monitoring of the system. The infusion system includes one or more sources of fluids to be infused, such as pumps or reservoirs, and a plurality of hose lines that carry the fluid to an entry point at the patient. A signal generator introduces a pressure signal into the fluid and a sensor, spaced some distance from the signal generator, receives the sensor signal and generates an input signal based on the sensor signal and transmits the input signal to an evaluation circuit. Information transmitted to the evaluation circuit is displayed visually, the information relating to operating status of fluid sources and lines, as well as to flow rates, blockages, leaks, etc.
    Type: Application
    Filed: May 17, 2017
    Publication date: May 31, 2018
    Inventors: David Grosse-Wentrup, Uvo Hölscher
  • Publication number: 20180147347
    Abstract: Methods and systems for configuring a plurality of infusion pumps according to a functional set. A method includes implementing a plurality of infusion pumps, each of the infusion pumps configured to administer medication to a patient, implementing a drug library, the drug library including at least one functional set defining a set of medications, receiving input data related to one of the at least one functional sets, obtaining a particular set of medications from the drug library corresponding to the input data, programming the plurality of infusion pumps according to the set of medications, and infusing the patient with the plurality of infusion pumps.
    Type: Application
    Filed: May 25, 2016
    Publication date: May 31, 2018
    Applicant: Smiths Medical ASD, Inc.
    Inventor: James B. DROST
  • Publication number: 20180147348
    Abstract: The invention provides for disabling of the audio bolus feature of a drug delivery system on the occurrence, or predicted occurrence, of certain events mitigating the problem of a user delivering unneeded drug. The invention provides a drug delivery system having at least one controller configured to autonomously modulate drug delivery from the drug delivery device, a sensor for measuring an analyte of the user, and an audio bolus feature, wherein the audio bolus feature is automatically disabled if the controller determines a therapeutically significant state is present.
    Type: Application
    Filed: November 27, 2017
    Publication date: May 31, 2018
    Inventors: Thomas MCCANN, Daniel FINAN, Anthony DIUBALDI, Brian LEVY
  • Publication number: 20180147349
    Abstract: Described and illustrated is a system for management of diabetes that includes an infusion pump, glucose sensor and controller with a method programmed into the controller. The infusion pump is configured to deliver insulin to a subject. The glucose sensor is configured to sense glucose levels in the subject and provide output signals representative of the glucose levels in the subject. The controller is programmed to switchover from one mode of MPC control based on a predetermined range of blood glucose values to another MPC mode based on a predetermined target.
    Type: Application
    Filed: January 29, 2018
    Publication date: May 31, 2018
    Inventors: Daniel FINAN, Thomas MCCANN
  • Publication number: 20180147350
    Abstract: The invention relates to an arrangement for detecting a position of a plunger (4) relative to a bung (3) in a drug cartridge (1), comprising a proximity sensor (5) located close to a distal end (6) of the plunger (4) facing the bung (3) and aligned to receive light reflected by the bung (3).
    Type: Application
    Filed: January 23, 2018
    Publication date: May 31, 2018
    Inventors: Paul Richard Draper, Anthony Paul Morris, Stephen Francis Gilmore
  • Publication number: 20180147351
    Abstract: A method of administering subcutaneous treatment to a patient is provided. The method includes delivering, by a needle-free injection device, a first volume of a treatment at a first location on a surface of a body of the patient; detecting a movement of the needle-free injection device relative to the first location; determining, from the movement of the needle-free injection device relative to the first location, a second location of the needle-free injection device relative to the first location; determining a second volume of the treatment to deliver at the surface of the body of the patient at the second location; and delivering, by the needle-free injection device, the second volume of the treatment at the second location on the surface of the body of the patient.
    Type: Application
    Filed: November 28, 2017
    Publication date: May 31, 2018
    Inventors: Patrick Anquetil, Ian Hunter
  • Publication number: 20180147352
    Abstract: The invention provides an injection device for delivering a dose of medicament from a syringe. The injection device comprises a housing (10), a plunger (110) moveably mounted within the housing, an actuation mechanism (120, 122) arranged to provide a forward biasing force to urge the plunger forward in use to express a dose of medicament and a trigger mechanism (40) arranged to (directly or indirectly) releaseably hold the plunger against the force of the actuation mechanism. The injection device further comprises a plunger velocity regulator comprising a cam surface (162) associated with one of the housing or the plunger, and a cam member (152) associated with the other of the plunger or the housing and arranged to engage the cam surface during actuation movement of the plunger such that axial movement of the plunger relative to the housing causes relative rotational movement of the cam member and limits the forward velocity of the plunger movement.
    Type: Application
    Filed: May 20, 2016
    Publication date: May 31, 2018
    Inventors: Matthew Farmer, Oliver Gould
  • Publication number: 20180147353
    Abstract: Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament (M), the housing having a distal end (D) and a proximal end (P) with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end (P), operate the syringe to supply the dose of medicament (M), and retract the syringe with the needle after delivering the medicament (M). An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.
    Type: Application
    Filed: January 25, 2018
    Publication date: May 31, 2018
    Inventors: Matthew Ekman, Yannick Hourmand, Timothy Donald Barrow-Williams
  • Publication number: 20180147354
    Abstract: The present disclosure relates to a portable pressure container for driving a medical device. The container includes a pressure housing confining an interior volume and a pressure outlet extending through the pressure housing. The interior volume comprises a liquid storage portion and a gas storage portion. The liquid storage portion and the gas storage portion are in flow connection with each other. The liquid storage portion is configured to store a liquid phase of a driving medium. The gas storage portion is configured to store a gas phase of the driving medium. The pressure outlet is only in flow connection with the gas storage portion.
    Type: Application
    Filed: May 6, 2016
    Publication date: May 31, 2018
    Inventors: Christian Nessel, Christian Dexheimer, Tobias Uth, Florian Hammen
  • Publication number: 20180147355
    Abstract: The present disclosure relates to a syringe for mixing two substances which have been retained separately inside the syringe, for instance in a storage condition. In particular the present disclosure relates to a syringe for 1) retaining a dry composition in a vacuum, and 2) mixing the dry composition with an aqueous medium to form a flowable substance. One embodiment relates to a syringe for retaining and mixing first and second substances comprising: a barrel comprising a sealable and/or closable distal outlet and a vacuum chamber for holding a first substance, a plunger incorporating a reservoir chamber for holding a second substance and configured to be axially displaced through a proximal end of the barrel, a membrane separating the vacuum chamber and the reservoir chamber, and a pointed member, such as one or more needles, for penetrating the membrane.
    Type: Application
    Filed: June 30, 2016
    Publication date: May 31, 2018
    Inventors: Kristian Larsen, Lise Sjørup Elle, Thomas Ingemann Jensen
  • Publication number: 20180147356
    Abstract: A syringe device that includes a stem, container, and a plunger, the plunger having tubes with a soluble substance that maintain a seal on compounds within the container's chamber, and/or a parabolic cover held in position by a soluble substance, thus allowing a multi-cycle usage to dispense medication to patients, even while preventing further use.
    Type: Application
    Filed: July 5, 2017
    Publication date: May 31, 2018
    Inventor: Leonard Allen Massey, JR.
  • Publication number: 20180147357
    Abstract: Carpule systems and methods of making and using the same are disclosed. In one embodiment, a carpule system includes a carpule having a carpule body that defines a first chamber and a second chamber. A divider can be disposed between the first and second chambers for isolating a first material in the first chamber from a second material in the second chamber. The carpule system may also include a carpule mixing device that displaces a portion of the divider for mixing the first and second materials to form a mixture and a carpule syringe that dispenses an amount of the mixture. The amount of the mixture being dispensed is measured via an audible sound and/or a tactile sensation provided by the carpule syringe. Systems and methods herein advantageously obviate the need for mixing powdered material via multiple syringes, reduce waste and cost, and improve the accuracy of administering pharmaceutical compositions.
    Type: Application
    Filed: November 29, 2016
    Publication date: May 31, 2018
    Inventors: Amir Marashi, Jack Krajekian
  • Publication number: 20180147358
    Abstract: Exemplary embodiments provide automatic injection devices, housing components for automatic injection devices and methods for fabricating the same. An exemplary housing of an automatic injection device may be overmolded with one or more gripping surfaces to facilitate gripping and manipulation of the automatic injection device by a user when performing an injection. In an exemplary embodiment, an overmolded left gripping surface may extend along a left side of the housing and an overmolded right gripping surface may extend along a right side of the housing opposite to the left side.
    Type: Application
    Filed: January 26, 2018
    Publication date: May 31, 2018
    Inventors: Joseph F. Julian, Chuan Li, Aaron B. Eiger, Mark Kurth, Sabrina Katz, Adam Callif, James C. Stango