Abstract: The purpose of the present invention is to provide a single cell analysis device in which the improvement of the nucleic acid capturing efficiency and the improvement of the cell capturing efficiency are both achieved and a highly accurate single cell analysis data is thereby obtained. The present invention relates to an improvement of a cell analysis device including a two-dimensional array chip having a plurality of cell capture parts capable of capturing a single cell in each of the capture parts, and nucleic acid capture parts corresponding to the respective cell capture parts, the nucleic acid capture parts being capable of capturing a nucleic acid extracted from the cell captured by the cell capture part.

Abstract: Through a novel primer design, multiplex pyrophosphorolysis activated polymerization uses multiple pairs of blocked primers to amplify multiple almost-sequence-identical templates located in one locus in a single reaction, greatly increasing the productivity of nucleic acid amplification.

Abstract: Sensitive, unbiased methods for genome-wide detection of potential off-target nuclease cleavage sites in DNA, e.g., in cell type-specific genomic DNA samples.

Abstract: This disclosure describes frameworks and techniques related to the random access of digital data encoded by polynucleotides. Digital data of a data file can be encoded as a series of nucleotides and one or more polynucleotide sequences can be generated that encode the digital data for the data file. The bits of the digital data can be segmented to produce multiple polynucleotide sequences that encode the bits of the digital data with each polynucleotide sequence encoding an individual segment of the digital data. The individual segments can be grouped together and associated with a group identifier. Each data file can be associated with a number of group identifiers and the number of segments in each group can be within a specified range. Primers corresponding to the group identifiers can be used to selectively access the polynucleotides that encode the digital data of a data file.

Abstract: The present invention generally relates to microfluidics and/or epigenetic sequencing. In one set of embodiments, cells contained within a plurality of microfluidic droplets are lysed and the DNA (e.g., from nucleosomes) within the droplets are labeled, e.g., with adapters containing an identification sequence. The adapters may also contain other sequences, e.g., restriction sites, primer sites, etc., to assist with later analysis. After labeling with adapters, the DNA from the different cells may be combined and analyzed, e.g., to determine epigenetic information about the cells. For example, the DNA may be separated on the basis of certain modifications (e.g., methylation), and the DNA from the separated nucleosomes may be sequenced using techniques such as chromatin immunoprecipitation (“ChIP”). In some cases, the DNA sequences may also be aligned with genomes, e.g., to determine which portions of the genome were epigenetically modified, e.g., via methylation.

Abstract: The application discloses circRNAs as new biomarkers for the development of heart failure after myocardial infarction; methods for the prediction and diagnosis of heart failure are provided based on measuring said one or more circRNAs; and kits and devices for measuring said circRNAs and/or performing said methods. Further provided are methods for treating patients at risk of heart failure based on the evaluation of said one or more circRNAs.

Abstract: The invention relates to a method for the diagnosis of non-alcoholic steatohepatitis (NASH), for determining the activity, the stage, or the severity of NASH or for classifying a subject as a potential receiver or non receiver of a treatment of NASH using circulating miRNAs and other blood circulating markers of liver damage, e.g. alpha 2 macroglobulin, HbA1c, N-terminal pro-peptide of collagen type III, miR-34 and miR-200. It also relates to a kit for implementing the method of the invention, and the compounds for use in a method for the treatment of NASH, wherein the subject to be treated is identified, evaluated or classified according to the method of the invention.

Abstract: The present invention relates to molecular signatures that can be used to identify patients diagnosed with an autoimmune disease, in particular with systemic lupus erythematosus for treatment with a CD40 or CD40L antagonist such as anti-CD40 antibody, anti-CD40L antibody or a binding fragment thereof. The signatures can also be used to monitor target engagement and response to treatment.

Abstract: The invention is a novel MECP2E1 splice variant and its corresponding polypeptide. The invention also includes methods of using these nucleic acid sequences and proteins in medical diagnosis and treatment of neuropsychiatric disorders or development disorders.

Abstract: The invention is a novel MECP2E1 splice variant and its corresponding polypeptide. The invention also includes methods of using these nucleic acid sequences and proteins in medical diagnosis and treatment of neuropsychiatric disorders or development disorders.

Abstract: The present disclosure relates to methods, compositions and systems for haplotype phasing and copy number variation assays. Included within this disclosure are methods and systems for combining the barcode comprising beads with samples in multiple separate partitions, as well as methods of processing, sequencing and analyzing barcoded samples.

Abstract: A method of detecting a combination of nucleic acid biomarkers in a human subject can include: obtaining a nucleic acid sample from the human subject; selecting the combination of nucleic acid biomarkers; analyzing a transcriptome of the human subject for the combination of nucleic acid biomarkers in the nucleic acid sample from the human subject; detecting in the nucleic acid sample the presence of the combination of nucleic acid biomarkers, wherein each nucleic acid biomarker in the combination of nucleic acid biomarkers has a variation from a transcription standard.

Abstract: Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.

Abstract: Disclosed are methods for determining the immunological status of the adaptive immune system of a subject by identifying and quantifying rearranged DNA (and/or subsequently transcribed RNA) sequences encoding T cell receptor (TCR) and/or immunoglobulin (IG) polypeptides, in a lymphoid DNA-containing sample from the subject. TCR and/or IG sequence diversity and sequence distribution permit immunocompetence and immune repertoire assessment and reflect the degree of T cell or B cell clonality and clonal expansion in the sample. Methods for stratifying patient populations on the basis of immunocompetence including likelihood of responding to immunotherapy are also described.

Abstract: A method of detecting a heat-resistant fungus, which has a step of identifying the heat-resistant fungus using the following nucleic acid (I) or (II): (I) a nucleic acid including a nucleotide sequence set forth in any one of SEQ ID NOS: 24 to 35 and 83 to 86, or a complementary sequence thereof; or (II) a nucleic acid including a nucleotide sequence resulting from a deletion, substitution, or addition of one to several nucleotides in the nucleotide sequence set forth in any one of SEQ ID NOS: 24 to 35 and 83 to 86 and being capable of detecting the heat-resistant fungus, or a complementary sequence thereof.

Abstract: A method of detecting a heat-resistant fungus, which has a step of identifying the heat-resistant fungus using the following nucleic acid (I) or (II): (I) a nucleic acid including a nucleotide sequence set forth in any one of SEQ ID NOS: 24 to 35 and 83 to 86, or a complementary sequence thereof; or (II) a nucleic acid including a nucleotide sequence resulting from a deletion, substitution, or addition of one to several nucleotides in the nucleotide sequence set forth in any one of SEQ ID NOS: 24 to 35 and 83 to 86 and being capable of detecting the heat-resistant fungus, or a complementary sequence thereof.

Abstract: Disclosed is a nucleic acid comprising a nucleotide sequence encoding (i) two or more reporters comprising a first reporter and a second reporter that is different from the first reporter; and (ii) one or more ribosomal skip sequences, wherein a ribosomal skip sequence is positioned between the first and second reporters, wherein the first and second reporters are stoichiometrically co-expressed from the nucleotide sequence and the nucleic acid does not comprise a cytomegalovirus-immediate early (CMV-IE) promoter. Also disclosed are methods of screening test compounds for ability to modulate a biological activity of interest using the nucleic acid, as well as related recombinant expression vectors, host cells, and populations of cells.

Abstract: The present invention provides novel methods, systems, tools, and kits for the simultaneous detection, identification and/or characterization of all viruses known or suspected to infect vertebrates. The methods, systems, tools, and kits described herein are based upon the virome capture sequencing platform (“VirCapSeq-VERT”), a novel platform developed by the inventors. The invention also provides methods and kits for designing and constructing of the virome capture sequencing platform.

Abstract: The present disclosure relates to compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also disclosed herein.

Abstract: The invention provides methods and devices for generating optical pulses in one or more waveguides using a spatially scanning light source. A detection system, methods of use thereof and kits for detecting a biologically active analyte molecule are also provided. The system includes a scanning light source, a substrate comprising a plurality of waveguides and a plurality of optical sensing sites in optical communication with one or more waveguide of the substrate, a detector that is coupled to and in optical communication with the substrate, and means for spatially translating a light beam emitted from said scanning light source such that the light beam is coupled to and in optical communication with the waveguides of the substrate at some point along its scanning path. The use of a scanning light source allows the coupling of light into the waveguides of the substrate in a simple and cost-effective manner.

Abstract: The invention relates to a method and an apparatus for producing a soluble carbohydrate containing fraction (10), in which lignocellulose material (3) formed by treating plant based raw material (1) is conducted into a separation stage (4). The method comprises at least one solid-liquid separation stage (4) for separating a soluble carbohydrate containing fraction (10) and/or a washing filtrate (12) from lignocellulose material (3), and at least a part of the soluble carbohydrate containing fraction (10) and/or the washing filtrate (12) is recirculated to the lignocellulose material (3) for increasing concentration of the soluble carbohydrate containing fraction, and solids (11) and at least a part of the soluble carbohydrate containing fraction (10) are supplied out from the separation stage. Further, the invention relates to the soluble carbohydrate containing fraction and the solid fraction, and their uses.

Abstract: A hot-rolled high-strength steel strip or sheet with excellent roll-forming characteristics and excellent stretch-flange formability suitable for automotive chassis part or the like and, more particularly, to a high-strength steel strip or sheet with tensile strength of 780 MPa or higher, or preferably 950 MPa or higher, with an excellent combination of total elongation, stretch-flange formability and fatigue resistance and to a method of manufacturing the steel strip or sheet, and to the use of the strip or sheet in a part.

Abstract: Steel for a suspension spring including, as a chemical composition, by % by mass: C: more than 0.40% and 0.65% or less; Si: 1.00% to 3.50%; Mn: more than 2.00% and 3.00% or less; Cr: 0.01% to 2.00%; V: 0.02% to 0.50%; P: 0.020% or less; S: 0.020% or less: N: 0.0100% or less; and a remainder of Fe and impurities, in which Kf is 280 or more, in which a structure contains a tempered martensite of which an area ratio is 90% or more, in which a Fe-based carbide precipitated in the tempered martensite is a cementite, and in which an average of an area ratios of prior austenite grains which stretch in a longitudinal direction of the steel and of which an aspect ratio exceeds 3.0, is 80% or more in a case of depths of 0.1 mm, 0.2 mm, and 0.3 mm in a sheet thickness direction from a surface of the steel.

Abstract: An process for the on-line quenching of seamless steel tube using residual heat, a method for manufacturing a seamless steel tube, and a seamless steel tube. The process for the on-line quenching of a seamless steel tube comprises the following steps: when the temperature of a tube is higher than Ar3, evenly spraying water along a circumferential direction of the tube so as to continuously cool the tube to be not higher than T° C., the cooling rate being controlled to be E1° C./s to E2° C./s to obtain a microstructure with martensite as the main composition, wherein T=Ms?95° C., Ms represents the martensitic phase transition temperature, E1=20×(0.5?C)+15×(3.2?Mn)?8×Cr?28×Mo?4×Ni?2800×B, and E2=96×(0.45?C)+12×(4.6?Mn), and the C, Mn, Cr, Ni, B and Mo in the equations each represents the mass percentages of corresponding elements in the seamless steel tube.

Abstract: A bulletproof steel plate with a tensile strength of 2000 MPa grade and a Brinell Hardness of 600 grade and a manufacturing method thereof, characterized by that the chemical elements in mass percentage thereof being: 0.35-0.45% of C, 0.80-1.60% of Si, 0.3-1.0% of Mn, 0.02-0.06% of Al, 0.3-1.2% of Ni, 0.30-1.00% of Cr, 0.20-0.80% of Mo, 0.20-0.60% of Cu, 0.01-0.05% of Ti, 0.001-0.003% of B, and the balance being Fe and inevitable impurities. The tensile strength of the steel plate can reach a grade of 2000 MPa and its Brinell Hardness can reach a grade of 600.

Abstract: A method for producing a coated steel sheet by reheating a steel slab containing 0.15-0.25 wt % of carbon (C), more than 0 wt % but not more than 1.5 wt % of silicon (Si), 1.5-2.5 wt % of manganese (Mn), more than 0 wt % but not more than 1.8 wt % of aluminum (Al), 0.3-1.0 wt % of chromium (Cr), more than 0 wt % but not more than 0.03 wt % of titanium (Ti), more than 0 wt % but not more than 0.03 wt % of niobium (Nb), and the balance of iron (Fe) and unavoidable impurities. Hot-rolling, cooling and coiling the steel slab, thereby producing a hot-rolled steel sheet. Pickling the hot-rolled steel sheet, then cold rolling. Annealing the cold-rolled steel sheet at a temperature between 820° C. and 870° C., followed by cooling at a finish-cooling temperature between 350° C. and 450° C.; tempering the cooled steel sheet at a temperature between 450° C. and 550° C.; and hot-dip galvanizing the tempered steel sheet.

Abstract: The present invention relates to a method, and system for performing such method, for producing a press hardened part (2?) of heat treatable material having zones of different structure by partially heating a blank (2) before the blank is processed. The method (100) comprises the steps of arranging (104) the blank in a furnace (10) for heating the blank to a temperature equal to or above the austenitization temperature of the material of the blank to get the blank into an austenitic phase, in a IR heating station (10) partially heating (106), by means of IR radiation (24), at least one first zone (2a) of the blank thereby keeping the at least one first zone of the blank in the austenitic phase, and arranging (108) the blank in a processing unit (30) for forming and quenching the blank to a press hardened part.

Abstract: A continuous annealing method for low coercive force cold-rolled electromagnetic pure iron plate and strip. Control parameters of each stages in a continuous annealing process are as follows: 750-850° C. at a heating stage; 750-850° C. at a soaking stage, the soaking time is 100-150 s; an outlet temperature of 575-675° C. at a slow-cooling stage, the cooling speed in slow-cooling stage is 2.5-10° C./s; an outlet temperature of 380-420° C. at a fast-cooling stage, the cooling speed of the fast-cooling stage is 15-25° C./s; and 270-310° C. at an overaging stage. The annealing medium is a non-oxidizing atmosphere composed of H2 and N2. After annealing, the cold-rolled electromagnetic pure iron plate and strip is leveled and pressed such that the leveling elongation rate of the plate and strip is controlled within the range of 0.2±0.1%.

Abstract: The device comprises a sonotrode (102) which can produce an oscillatory movement by means of a transducer (101) in order to generate ultrasound oscillation waves in said light alloy melt, when said sonotrode (102) and said melt are in contact, so as to perform the degassing; and an electronic-mechanical component (104) embedded in part of the sonotrode (102) for detecting the state of the service life or an anomaly of the sonotrode (102). The electronic-mechanical component (104) includes means for sending at least one notification signal to an electronic remote control equipment (103), forming a system together with the device. The electronic control device (103) is configured for sending an activation or deactivation signal for activation or deactivation of said transducer (101), taking into account said at least one notification signal.

Abstract: A process for recovering silver from silver-bearing gold concentrate or other silver-bearing material which may comprise adding oxygen, water, and/or acid to an acidulated concentrate slurry of an input silver bearing material and reacting them together in an autoclave at an elevated pressure and temperature in a pressure oxidation step; processing the oxidized concentrate slurry in a post pressure oxidation conditioning step; applying a first solid/liquid separation and wash step and a filter and wash step to form a first washed slurry/solid and first acid-containing solutions; reacting the first washed slurry/solid with sulfur dioxide in a reductive leach step; applying a second solid/liquid separation and wash step to form a second washed slurry/solid and second acid-containing solutions; and applying an optional surface cleaning step, to produce a free-milling silver-bearing material, which is amenable to conventional cyanidation to recover the silver therefrom.

Abstract: A method includes contacting a coal feedstock with an acidic solution to form residual coal and a leachate. The method further includes separating the residual coal from the leachate where the leachate contains rare earth elements and where the residual coal has preserved organic content and reduced inorganic content. Another method includes contacting a coal feedstock with a basic solution to form residual coal and a leachate. The method further includes separating the residual coal from the leachate where the leachate contains rare earth elements and where the residual coal has reduced inorganic content, but preserved organic content.

Abstract: Magnesium alloys comprising a long period stacking order (LPSO) phase having an 14H-i or an 18R-i structure are provided. The alloys comprise magnesium as a majority element, a first alloying element that is larger than magnesium and a second alloying element that is smaller than magnesium.

Abstract: A composition includes a metal alloy matrix comprising iron and a plurality of nanoparticles dispersed within the metal alloy matrix. Each nanoparticle of the plurality comprises an oxide of a rare-earth metal and at least one metal selected from the group consisting of tantalum, niobium, vanadium, and titanium. Some compositions include a metal alloy matrix comprising iron and a plurality of nanoparticles comprising at least two different oxides of rare-earth metals dispersed within the metal alloy matrix. Some methods include mixing an oxide of a rare-earth metal with a first metal and a second metal. Other methods include mixing a plurality of particles comprising at least one oxide of a rare-earth metal with a molten metal comprising iron. Each particle of the plurality may exhibit a density between about 6.9 g/cm3 and about 9.0 g/cm3.

Abstract: A ferritic stainless steel having sufficient corrosion resistance and excellent formability and ridging resistance. The ferritic stainless steel having a chemical composition comprising, by mass %, C: 0.005% or more and 0.035% or less, Si: 0.25% or more and less than 0.40%, Mn: 0.05% or more and 0.35% or less, P: 0.040% or less, S: 0.01% or less, Cr: 15.5% or more and 18.0% or less, Al: 0.001% or more and 0.10% or less, N: 0.01% or more and 0.06% or less, and the balance being Fe and inevitable impurities. Si and Mn satisfy the relational expression 29.5×Si?50×Mn+6?0, where Si and Mn in the relational expression respectively denote the content, by mass %, of the corresponding chemical element.

Abstract: Provided is a hollow seamless steel pipe for a spring, including by mass %, C: 0.2 to 0.7%; Si: 0.5 to 3%; Mn: 0.1 to 2%; Cr: more than 0% and 3% or less; Al: more than 0% and 0.1% or less; P: more than 0% and 0.02% or less; S: more than 0% and 0.02% or less; and N: more than 0% and 0.02%: or less, with the balance being iron and inevitable impurities, wherein, an uneven thickness ratio calculated by formula (1) below is 7.0% or less.

Abstract: The present invention addresses the problem of providing: a stainless steel which is provided with gas corrosion resistance suitable for substrates of compound thin film solar cells without requiring a surface treatment such as coating or plating; a method for producing this stainless steel; and a compound thin film solar cell which uses this stainless steel as a substrate. In order to solve the above-described problem, the present invention is characterized by forming an Fe—Cr—Al oxide film which has a film thickness of 15 nm or less and contains, in mass %, 0.03% or less of C, 2% or less of Si, 2% or less of Mn, 10-25% of Cr, 0.05% or less of P, 0.01% or less of S, 0.03% or less of N and 0.5-5% of Al, with the balance made up of Fe and unavoidable impurities, and wherein the maximum value of the Al concentration is 30% by mass or more and the Fe concentration at the depth of 2 nm from the surface is 30% or less in the profile of cation fractions excluding O and C ions.

Abstract: An austenitic stainless steel according to the present invention has a chemical composition containing, by mass %: C: 0.01 to 0.15%; Si: 2.0% or less; Mn: 3.0% or less; Cr: 10.0 to 20.0%; Ni: 5.0 to 13.0%; N: 0.01 to 0.30%; Nb: 0 to 0.5%; Ti: 0 to 0.5%; and V: 0 to 0.5%, with the balance: Fe and impurities, wherein an average grain size is 10.0 ?m or less, a difference in value of an average lattice constant dAve. (={d?(111)×I?(111)+d?(200)×I?(200)+d?(220)×I?(220)+d?(311)×I?(311)}/{I?(111)+I?(200)+I?(220)+I?(311}) of an austenite phase between a surface portion and a center portion is 0.010 ? or more, and a value of a diffraction peak integrated intensity ratio r (=100×?I?/?IALL) at a surface is 95% or more.

Abstract: An Mg-containing Zn alloy coated steel including a steel and a metallic coating layer placed on a surface of the steel, in which the metallic coating layer is a layered structure of a flat-form metal particle having a particle diameter of from 5 to 100 ?m, and a thickness of from 0.5 to 30 ?m, the composition of the metal particles include, in terms of % by mass, Zn from 11 to 80%, Al from 3 to 80%, Mg from 8 to 45%, and Ca from 1 to 5%, while the balance is impurities, and the Zn content, the Al content, and the Mg content in terms of % by mass satisfy Zn+Al>Mg, and in which the metal particles include a quasicrystalline phase, an MgZn2 phase, and a balance structure, in which the total area fraction of the quasicrystalline phase and the MgZn2 phase is 45% or more, the area fraction of the balance structure is from 0 to 55%, the area fraction of the quasicrystalline phase is 20% or more, and the area fraction of the MgZn2 phase is 3% or more.

Abstract: An apparatus for controlling deposition of material from a plasma transferred wire arc (PTWA) torch within a bore is provided. The apparatus includes a duct and a plurality of cannons. The duct includes a plurality of fluid passageways separated by cross-members. The plurality of cannons are disposed adjacent and downstream from the plurality of fluid passageways of the duct. The flow of fluid is simultaneously directed through all of the fluid passageways and the plurality of cannons and past the PTWA torch in the bore.

Abstract: This invention discloses a metal coating method whereby an abrasion resistant and wear resistant coating is first applied to the that portion of a metal object of extended size to be protected, the coating is then fused onto the metal object with the use of a temperature controlled induction heater, which results in a metal object, at least a portion of which is more abrasion resistant and wear resistant than the uncoated metal object.

Abstract: The disclosure provides methods of making iron-based alloys, as well as resulting alloys. An iron-based alloy containing a small amount of nickel (e.g., 0.5 to 2.0 wt %) is annealed and machined. The alloy is sufficiently ductile to reduce the likelihood of cracking, while not sufficiently high to result in a hardened alloy. After the alloy is shaped, the alloy is hardened by nitriding.

Abstract: A process comprising: placing a boronizing powder composition in the interior of a metal pipe comprising a first end, a second end, an inside surface and an outside surface; heating the pipe in a vessel having an interior, to a temperature from 1400° F. to 1900° F., thereby forming spent boronizing reaction gases and a borided layer on the inside surface, wherein the vessel interior has an atmosphere that surrounds the outside surface of the metal pipe; and flowing the spent boronizing reaction gases into the atmosphere surrounding the outside surface of the pipe, thereby forming an oxygen-depleted atmosphere.

Abstract: A process comprising: placing a boronizing powder composition in a metal pipe comprising a first end, a second end, an inside surface and an outside surface; heating the pipe to form a borided layer on the inside surface, and spent boronizing powder; removing the spent boronizing powder from the pipe, thereby forming an empty boronized pipe; heating the empty boronized pipe to above its austenitizing temperature, thereby forming an austenitized pipe; quenching the austenitized pipe, thereby forming a quenched pipe; tempering the quenched pipe, thereby forming a tempered pipe; and threading the tempered pipe.

Abstract: A reactive sputtering apparatus performs deposition in any of compound, transition, and metallic modes by employing a target and reactive gas, wherein the reactive sputtering apparatus includes an inert-gas feeding unit, a reactive-gas feeding unit, a power supply unit to supply electric power to the target, a detection unit to detect plasma emission generated upon supply of the electric power to the target, and a control unit to adjust a reactive-gas flow rate to maintain, at a designated value, plasma emission intensity at a wavelength or a value calculated from plasma emission intensities at plural wavelengths, and wherein the control unit controls the designated value for the plasma emission intensity or the calculated value thereof such that a ratio V/Vc of a cathode voltage V in the transition mode to Vc in the compound mode comes closer to a preset value, those voltages being detected during the deposition.

Abstract: A method of fabricating a hydrophilic-hydrophobic transformable composite film is provided. The method includes forming a silicon-containing layer on an iron-containing substrate; coating a titanium-containing sol-gel film on the said silicon-containing layer; and heating the iron-containing substrate with the silicon-containing layer and the titanium-containing sol-gel film thereon.

Abstract: An object of the present invention is to improve the mechanical strength of a sputtering target, and in order to achieve such an object, there is provided a sputtering target material including: in at. %, 10 to 50% of B; 0 to 20% in total of one or more elements selected from Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Mn, Re, Ru, Rh, Ir, Ni, Pd, Pt, Cu, and Ag; and the balance of at least one of Co and Fe, and unavoidable impurities, in which a hydrogen content is 20 ppm or less.

Abstract: According to one embodiment, a collimator includes peripheral openings that extend between a grid region and a peripheral frame, are larger in size than unit through-holes, and penetrate through the collimator in a first direction. The peripheral openings include first peripheral openings located between first end walls and the peripheral frame.

Abstract: The present disclosure provides an apparatus for loading a substrate into a vacuum processing module. The apparatus includes a Bernoulli-type holder having a surface configured to face the substrate, and a gas supply configured to direct a stream of gas between the surface and the substrate, wherein the Bernoulli-type holder is configured to provide a pressure between the substrate and the surface configured for levitation of the substrate. The substrate is a large area substrate.

Abstract: The cutting plate 12 includes a base body 22 made of a sintered hard metal. On a top side 23 of the base body 22 there are one or multiple intermediate layers 25 that include an adhesion-promoting layer 26. The adhesion-promoting layer 26 is made of a boron-containing nitride of a transition metal of group IV, group V, and group VI, and contains a plurality of small plates 31 oriented at an angle relative to the top side 23. A diamond layer that is grown on the adhesion-promoting layer 26 includes stalk-shaped crystals, oriented vertically relative to the top side 23, having an aspect ratio greater than three.

Abstract: In one aspect, the invention is formulations comprising both organoaminohafnium and organoaminosilane precursor compounds that allows anchoring both silicon-containing fragments and hafnium-containing fragments onto a given surface having hydroxyl groups to deposit silicon doped hafnium oxide having a silicon doping level ranging from 0.5 to 8 mol %, suitable as ferroelectric material. In another aspect, the invention is methods and systems for depositing the silicon doped hafnium oxide films as ferroelectric materials using the formulations.