Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Abstract: The invention provides a neck-worn sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The neck-worn sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Abstract: A system (1) for detecting vital physiological parameters of a subject (10), comprising support means (15) which can be associated with the subject (10) and are connected to acquisition means (20) configured to acquire synchronously an ECG signal and a PPG signal of the subject (10); the system (1) comprises processing means (40) which are connected to the acquisition means (20), the processing means (40) comprising a systolic and diastolic arterial pressure module (43) configured to calculate a vital physiological parameter related to systolic and diastolic arterial pressure, which can be transmitted to at least one telematic device (5) by way of transceiver means (60) configured to transmit the vital physiological parameter toward the telematic device (5).

Abstract: A system for acquiring physiological data from a patient, the system comprising: a smartphone configured for wireless communication; an adapter for releasably mounting to the smartphone; a sensor module for releasably mounting to the adapter, the sensor module comprising at least one sensor for acquiring physiological data from the patient; and a software app running on the smartphone for (i) wirelessly controlling operation of the sensor module and wirelessly receiving the physiological data from the sensor module, and (ii) wirelessly communicating with a remote location.

Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Abstract: A smart personal portable blood pressure measuring system comprises a smart blood pressure measuring base, and a portable blood pressure measuring apparatus comprising a metal electrode detecting unit for detecting an electrocardiography (EKG) signal, a photoplethysmography detector for detecting a photoplethysmography (PPG) signal, a storage unit, a first central processor, a first power supply, and a first coupling interface unit. The storage unit stores a plurality of blood pressure values and a blood pressure algorithm. The first central processor performs a calculation according to the EKG signal, the PPG signal and the blood pressure algorithm. The first power supply provides the necessary power for operating the portable blood pressure measuring apparatus. The first coupling interface unit is coupled to the smart blood pressure measuring base so that the smart blood pressure measuring base is capable of transmitting data to the portable blood pressure measuring apparatus.

Abstract: Device and methods for a wearable medical device are disclosed. The device and methods use an on-board mobile system to alert emergency services when the user is in cardiovascular distress. The device takes advantage of newly miniaturized electrocardiograph, pulse oximetry sensors, mutual reinforcement and anomaly detection algorithms. Electrocardiograph waveforms are recorded digitally for physician review with emphasis on critical events. In the occurrence of a immediate critical-need cardiac event, the system will contact emergency services (EMS) for assistance. The system is a biometric monitoring system that implements key concepts of cardiovascular monitoring through pulse oximetry and electrocardiography (ECG). The system implements key concepts of ECGs and active/capacitive electrodes to produce a wireless network of (individually isolated) ECG nodes that can produce a system ranging from 3 to 16 leads.

Abstract: The present invention relates to a system and methods generally aimed at surgery. More particularly, the present invention is directed at a system and related methods for performing surgical procedures and assessments involving the use of neurophysiology.

Abstract: A system for secure physiological data acquisition and delivery is provided. The system includes a monitoring patch that includes a flexible backing; a pair of electrocardiographic electrodes included on a contact surface of each end of the flexible backing; a receptacle affixed to a non-contacting surface of the flexible backing and including an electro-mechanical docking interface for interfacing with a monitor recorder; a pair of flexible circuit traces affixed at each end of the flexible backing with each circuit trace connecting one of the electrocardiographic electrodes to the electro-mechanical docking interface; and a circuit operable to store an identifier associated with the patch and an encrypted password necessary to access physiological monitoring data obtained using the patch identified by that identifier, the circuit configured to provide via the electro-mechanical docking interface the password and the identifier to the monitor recorder.

Abstract: A system includes an ambulatory medical device and a server.

Abstract: Fast recovery electrocardiogram (ECG) signal method and apparatus are provided. In one embodiment, an ECG apparatus includes an input for receiving a biometric cardiogram signal, such as a Wilson Central Terminal (WCT) signal, and a combiner, such as an adder, for producing a compensated signal. Processing circuitry produces an ECG reflective of the compensated signal and also outputs a signal corresponding to high frequency response of the compensated signal to compensate for low response of the biometric cardiogram signal to high frequency spikes. A resultant ECG is produced by the processing circuitry having pacing signal contribution within the biometric cardiogram signal cancelled.

Abstract: A method includes, in a processor, receiving example representations of geometrical shapes of a given type of organ. In a training phase, a neural network model is trained using the example representations. In a modeling phase, the trained neural network model is applied to a set of location measurements acquired in an organ of the given type, to produce a three-dimensional model of the organ.

Abstract: A method is implemented by a computer, and includes: (a) acquiring at least one set of waveform data having a time duration from physiological information waveform data; (b) classifying a waveform included in the waveform data into a predetermined type of waveform; (c) determining validity of a classification result of the waveform; and (d) correcting the classification result in accordance with the validity of the classification result.

Abstract: A system and method for facilitating a cardiac rhythm disorder diagnosis based on subcutaneous cardiac monitoring data with the aid of a digital computer are provided. Cutaneous action potentials of a patient are recorded as electrocardiogram (EGC) data over a set time period using a subcutaneous insertable cardiac monitor. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks and the associated heart rates in the R-R interval plot.

Abstract: A method of attaching electrodes to a patient, the method comprises the steps of providing a squeezable member having a hollow interior, wherein a skin abrasive solution is in the interior, wherein the squeezable member includes a restrictive member having a restrictive opening for restricting flow of the skin abrasive solution out of the squeezable member, and a tip through which the solution leaving the restrictive member exists the squeezable member; squeezing the squeezable member; scrubbing skin portions of the scalp of the patient with the tip; and attaching electrodes to the skin portions of the patient's scalp.

Abstract: Minimally invasive systems, and tools provided herein in novel enhanced and modified form for this application used has Used deep brain knowledge and structural data to generate novel enhanced intracranial signals to develop, characterize and ameliorate challenges and disease states with application specific tools modified from tradition EEG for Epilepsy to address a myriad of conditions in patients, without any need for invasive protocols traditionally employed. Also disclosed is a novel enhanced system that can be permanently implanted (like a pacemaker) that can both sense epileptiform activity, as well as apply a current to the seizure focus and arrest seizure progression.

Abstract: The invention provides a neck-worn sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The neck-worn sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Abstract: Apparatus, system, and computer-readable media measure electroencephalography (EEG) signals or ERG signals generated from a device that presents a series of images on a timing cycle to a subject. The apparatus comprises a Central Processing Unit (CPU), Power Supply Unit (PSU), Random Access Memory (RAM), and a hard drive (HDD). The apparatus further includes at least one electrode and a photo-sensor like a photodiode for conversion of light into electric current. The CPU is operable with software for converting the EEG or ERG signals evoked from the visual stimuli to provide data and retrieving the status of EEG signals.

Abstract: In order to stably detect biological information such as the heartbeat, respiration, and pulse waves of a living organism, a biological information detection system that detects biological information comprises: a transmission antenna arranged on one side of the living organism and irradiating radio waves of prescribed polarized waves on to the living organism; a reception antenna arranged on the other side of the living organism and receiving transmitted waves being polarized waves orthogonal to the radio waves of prescribed polarized waves in a step in which same are transmitted through the living organism; and a detection unit that detects biological information on the basis of the transmitted waves received by the reception antenna.

Abstract: In a method for analyzing acquired magnetic resonance images, an image series is provided that includes acquired magnetic resonance images of a slice of an object, picture elements of the acquired magnetic resonance images of the image series are fitted to generate a parameter map and an error map, the acquired magnetic resonance images are automatically segmented to generate image segments, histograms of the parameter map and the error map are generated based on the image segments, and the histograms are analyzed to generate an output of analysis results and/or generate a visualization including the parameter map, the error map, and the image segments. The acquired magnetic resonance images can have a variation of a contrast-determining acquisition parameter.

Abstract: In a method for filtering magnetic resonance (MR) image data, complex MR image data is acquired from a region to be imaged, and a sliding window averaging is applied to the complex MR image data to generate filtered MR image data. For each window position of the sliding window averaging: a phase variation of the complex MR image data of individual image points of a sliding window is estimated with a model using a linear phase progression, and filtered complex MR image data is generated based on the estimated phase variation of the complex MR image data. The generation of the filtered complex MR image data uses an average formation of the complex MR image data of the individual image points of the sliding window.

Abstract: A guidewire system comprises a guidewire supporting a distal ferrule in the proximal end of a guidewire lumen. The distal ferrule has a ferrule opening that is sized to snuggly receive the proximal end of a distal optical fiber with a distal portion of the distal optical fiber extending into the guidewire lumen. However, the proximal end of the distal optical fiber only occupies a distal portion of the opening in the distal ferrule, leaving a proximal portion of that opening unoccupied. That way, the distal end of a proximal optical fiber can be received into the unoccupied proximal portion of the opening in the distal ferrule to optically connect to the distal optical fiber. Having the proximal and distal optical fibers coaxially aligned in a common opening in a ferrule received in a guidewire ensures that the optical fibers are optically connected to each other in a precise manner so that light can be transmitted along them with minimal losses.

Abstract: A needle assembly for an ultrasound imaging system includes a needle having a proximal end and a distal end. The distal end is adapted to be inserted into a patient. The needle assembly also includes an optical sensor assembly secured to the distal end of the needle. The optical sensor assembly has a field of vision that includes the distal end of the needle and an environment surrounding the distal end of the needle as the needle is inserted into the patient towards a target site. In addition, the needle assembly includes a controller communicatively coupled to the optical sensor assembly. Thus, the controller is configured to receive and process one or more sensor signals from the optical sensor assembly in real-time.

Abstract: A wireless circuit includes a housing, such as a hermetic housing, and at least one antenna coil wound about a coil axis within the housing. The coil axis may be substantially parallel to at least one wall of the housing, wherein the wall parallel to the coil axis is substantially thinner than other walls of the housing.

Abstract: Embodiments of the disclosure can include systems, methods, and devices for detecting and identifying certain substances, such as volatile organic compounds (VOCs), volatile gases (VGs), and ketones, in the exhaled breath of a subject or person in real-time.

Abstract: A flow rate detector of an exhalation measurement device includes: a pipe body having a flow inlet at a first end into which exhalation flows, and a flow outlet at a second end out of which exhalation flows; and a differential pressure sensor connected to the pipe body. The pipe body includes: a partition gasket which partitions the inside of the pipe body into a flow-in space of exhalation and a flow-out space of exhalation; a connection aperture being provided at the flow-in space and connecting the differential pressure sensor to the flow-in space; a connection aperture being provided at the flow-out space and connecting the differential pressure sensor to the flow-out space; and an air duct of an elongated shape, extending through the partition gasket and allowing the flow-in space and the flow-out space to communicate with each other.

Abstract: The present invention provides an apparatus for measurement of a limb circumference, comprising a pull string module, a first measurement module and a second measurement module. The pull string module comprises a surrounding component, wherein the surrounding component comprises an encircling part disposed around a limb of an individual; the first measurement module is disposed at the pull string module and moves alone the longitudinal axis of the limb and meanwhile measures the length of the limb; and the second measurement module measures the length of the encircling part simultaneously when the first measurement module move alone the limb, so as to determine the correlation between the limb length and the limb circumference. The present invention further provides a device including two or more apparatuses of the present invention to measure the limb compliance and to be used in the treatment of lymphedema.

Abstract: Systems, devices, and methods for providing procedure-specific workflow guidance are provided. The workflow guidance may include providing selectable options on a display device to a user including a selectable option to select a target vessel and a prompt to move an intravascular imaging device within the selected target vessel. Imaging data is received from the intravascular imaging device within the selected target vessel. The workflow guidance may be used to identify an area of interest within the selected target vessel and automatically display vessel measurements corresponding with the area of interest on the display device.

Abstract: A non-contact respiratory monitoring system comprises a magnetic microwire sensor coil that detects magnetic field changes due to motion of a magnet attached to a patient's chest. Field lines emanating from the magnet are parallel to a circumferential loop area of the coil and the coil is positioned at a distance to magnetically couple to the magnet. Impedance in the coil changes when the distance of the magnet to the coil changes due to the patient's breathing. An alternating voltage across coil is modified by the change in impedance. An impedance analyzer coupled to the coil applies the alternating voltage and measures the impedance changes. A computer system controls operation of impedance analyzer, receives respiratory monitoring information based on the coil's impedance changes from the impedance analyzer, and generates a graphical display of the respiratory monitoring information.

Abstract: A system and method are provided for monitoring body kinematics. A wearable coil configuration of the system comprises at least first and second electrically-conductive coils adapted to be secured to a subject in a predetermined spatial relationship and orientation relative to one another. The first coil acts as a first transmitter and generates a first magnetic flux when a first electrical current is passed through it. The second coil acts as a receiver. The first magnetic flux induces a first electrical current or voltage in the second coil. A measurement instrument of the system is configured to measure the first electrical current or voltage and to output a first measurement signal. A processor, which may be part of, or external to, the system is configured to execute a motion monitoring algorithm that processes at least the measurement signal to determine at least a first motion made by the subject.

Abstract: The invention relates to an optical measurement system (10) and measurement method for coaching an individual. The optical measurement system comprises a cloud database (8), a wireless communication device (7) and a vertical self-supporting equipment box (2) comprising a data processing device (20) comprising a computer program configured to measure ground contact and/or reaction time and position of a body part (1a) of a person (1) within a predetermined reaction area (6).

Abstract: A middle ear sound transmission characteristics evaluation system includes a probe; a measuring probe that includes an actuator that vibrates the probe and a force sensor that outputs a voltage in accordance with a reaction force exerted to the actuator when a tip of the probe is brought into contact with ossicles; an electrode that is installed on a round window or near a round window and detects a potential value of a cochlear microphone when vibration is applied to the ossicles by the probe; a database that stores a sensor voltage value output by the force sensor before surgical treatment, the potential value detected by the electrode, and surgical details; and a surgical details proposing unit that proposes selected surgical details on the basis of the magnitude of at least one of the sensor voltage value and the potential value measured before surgery with reference to the sensor voltage values, potential values, and surgical details stored in the database.

Abstract: The present disclosure relates to a device and method for detection and compensation for an oblique ear-probe insertion in especially hearing testing diagnostic setups. More particularly the disclosure relates to detecting an oblique probe insertion from an ear-probe measurement and estimated characteristic impedances and compensate for its effect on the ear-canal reflectance.

Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Abstract: The invention relates to devices, systems, and methods for estimating a patient BUN level prior to a dialysis session based on data received when introducing an ammonium removal solution through a zirconium phosphate sorbent module. The systems and methods can introduce an ammonia removal solution and determine an ammonia content of the ammonium removal solution effluent to estimate the patient pre-dialysis BUN level.

Abstract: Provided are a microneedle electrode sensor for nonenzymatic monitoring of blood sugar, a method of manufacturing the sensor, and a method of nonenzymatically measuring blood sugar using the sensor. The method of manufacturing the microneedle electrode sensor includes (a) forming multiple microneedle shapes in a substrate, (b) coating the entire area of the substrate with a passivation agent, and (c) coating a microneedle reactive portion disposed at a tip of each microneedle with a glucose oxidation catalyst.

Abstract: An apparatus and method for measuring a biosignal are provided. The apparatus may include an optical sensor configured to emit light in a measurement region to an object of interest, and receive an optical signal reflected from the object of interest. The apparatus may include a bioelectrical impedance sensor configured to measure a depth-specific bioelectrical impedance in the measurement region of the optical sensor.

Abstract: Methods of compensating for ambient temperature using temperature sensors, the method comprising: sampling at a first sampling rate, with a processor, first temperature measurements from a first temperature sensor on an on-body sensor. Then determining, with a processor, first ambient-compensated temperatures from the first temperature measurements; and determining, with a processor, final ambient-compensated temperatures by applying a correction gain or factor to the first ambient-compensated temperatures. Wherein the correction gain or factor changes value at a slower rate than the sampling rate.

Abstract: An apparatus is provided which comprises: a substrate comprising a transparent material; and an array of transparent active devices disposed on the substrate, wherein each transparent active device comprises a sensing element associated with the transparent active device.

Abstract: An antioxidant sensor includes a first light source configured to emit light having a first wavelength onto an object; a second light source configured to emit light having a second wavelength onto the object; a third light source configured to emit light having a third wavelength onto the object, the first wavelength, the second wavelength, and the third wavelength being different from each other; a light receiver configured to receive light reflected or scattered from the object; and a processor configured to obtain a hemoglobin index by driving the first light source and the second light source, and to obtain an antioxidant signal of the object by driving the third light source based on the obtained hemoglobin index satisfying a condition.

Abstract: The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

Abstract: A measuring apparatus includes a first light source for emitting light of a first wavelength, a second light source for emitting laser light of a second wavelength different from the first wavelength, a first optical detector for receiving scattered laser light of the second wavelength from a measured part, a second optical detector for receiving transmitted light of the first wavelength from the measured part, a third optical detector for receiving transmitted laser light of the second wavelength from the measured part, and a controller configured to measure a blood flow amount based on an output of the first optical detector and an oxygen saturation based on outputs of the second optical detector and the third optical detector.

Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.

Abstract: Certain embodiments of a sensor cartridge element include a sensor module, an electrode arrangement installed on the sensor module, and a delivery arrangement securely coupled to the sensor module. The sensor module includes an analysis cell and a skin piercing member. The electrode arrangement generates an electrical signal when exposed to a fluid sample collected in the analysis cell. The delivery arrangement includes a drug reservoir, a piston chamber, and a valve arrangement providing selective fluid communication between the drug reservoir and the piston chamber. Metering electronics and an actuator can manage collection of fluid samples and/or dispensing of drug doses.

Abstract: A hand-held applicator (10) for collecting, mixing, diluting and discharging a sample liquid, comprising a main body (20) having an inlet-aperture (24), an outlet-aperture (26) and a chamber (22) for storing a liquid solution, wherein the chamber is connected to the inlet-aperture and the outlet-aperture, a lid (12) for covering the inlet-aperture and a tube (40), moveably supported in the inlet-aperture when the lid is covering the upper portion of the main body, wherein the tube (40) is moveable between a predetermined position outside the chamber and a position, in which the tube is at least partly located in the chamber.

Abstract: According to some aspects, disclosed methods and systems may include having a user input one or more speech commands into an input device of a user device. The user device may communicate with one or more components or devices at a local office or headend. The local office or the user device may transcribe the speech commands into language transcriptions. The local office or the user device may determine a mood for the user based on whether any of the speech commands may have been repeated. The local office or the user device may determine, based on the mood of the user, which content asset or content service to make available to the user device.

Abstract: A mental impairment detection system and non-invasive method of detecting mental impairment of a user are provided. A test (e.g., an inhibitory reflex test or a sustained attention test) is administered to the user, brain activity in a frontal lobe of the user is non-invasively detected while the test is administered to the user, and a level of mental impairment of the user is determined based on the brain activity detected in the frontal lobe of the user.

Abstract: There are described headphones comprising earcups to be placed about ears of a user, with a headband linking the earcups and to be extending above a head of the user. A flexible band distinct from the headband is secured below the headband for contact with the head of the user. Removable headband sensors are embedded in the flexible band and have a portion thereof protruding downwardly from the flexible band to reach the scalp. The flexible band has a flexibility which makes the flexible band deform under the weight of the earcups to conform with the head of the user to ensure high quality contact between the headband electrodes and the scalp. There are further provided earcup electrodes on the earcups for contact with a region on or behind an ear of the user. Signals from the electrodes can be used for different purposes such as concentration monitoring and feedback.

Abstract: Disclosed embodiments describe techniques for body analysis based on wearable sensors on an individual. The body analysis is based on movement assessment metric usage. The wearable sensors include muscle activity sensors, skeletal movement sensors, stretch sensors, inertial measurement sensors, or linear displacement sensors. Data is obtained from a wearable muscle activity sensor. Muscle activity over a time period is determined using the data obtained from the wearable muscle activity sensor. A movement assessment metric is calculated based on the muscle activity over the time period. The movement assessment can include body posture symmetry. The movement assessment metric is output, where the outputting can include displaying an animation of the muscle activity in a context of an overall body. The movement assessment can comprise an ergonomic assessment for the individual.