Abstract: The anesthesia systems have an integrated, extendable clinical center and clinician/anesthesia office that accommodates for a physical separation of clinical and clerical functions. The anesthesia system includes an alarm reversion system which enables a predefined alarm limit to be set and then to be automatically reverted back to an alarm limit existing just before the predefined alarm limit was set.

Abstract: An atomizer cover which is made of glass, plastic, silicone, metal or glass-lined metal for a vaporizing device wherein a side air inlet hole through the atomizer cover is located at a lower portion of the cover, wherein upon assembly of the cover with an atomizer and an atomizer base, the side air inlet hole is located near the atomizer and atomizer base, at or below the atomizer cup level, which creates a vortex of air to increase the efficiency in pulling of the aerosol or vapor from the interior of the atomizer cover, while cooling down the aerosol or vapor which is then inhaled by the user.

Abstract: Disclosed is a nebulizer having attached housing, which is attached in a way that permits removal, which housing holds containers of liquid medication for dispensing via nebulization, which nebulizer is constructed to allow containers holding the medication to be used and held within the housing provided that such containers match or conform to the certain mechanical requirements of the nebulizer and housing.

Abstract: A process for manufacturing a membrane of nozzles of a spray device, comprising the steps of laying a substrate, forming a membrane layer on the substrate, forming a plurality of nozzles in the membrane layer, forming a plurality of supply channels in the substrate, each supply channel being substantially aligned in a vertical direction to a respective nozzle of the plurality of nozzles and in direct communication with the respective nozzle.

Abstract: A disinfecting mat device cleans and sanitizes surfaces of objects coming into contact with the mat. The device includes a mat comprising a bottom wall, a perimeter wall, and an top wall defining an interior space of the mat. A compressible reservoir is positioned in the interior space and a fluid is positioned in the reservoir. An air chamber is positioned in the interior space. A plurality of ducts extends through a lower interior wall wherein each duct has an upper end in fluid communication with the air chamber and a lower end positioned adjacent to the reservoir. A plurality of tubes is in fluid communication with the reservoir extending through the top wall wherein each tube delivers the fluid in the reservoir to an upper surface of the top wall when the air chamber is compressed.

Abstract: An electronic cigarette is provided, which comprises a battery component. A battery, a PCB board and a press-key switch are provided in the battery component, and the press-key switch is set on the PCB board. An end face of the battery is located opposite one end face of the PCB board. A first electrode pin and a second electrode pin are provided on one end face of the battery, wherein the end face of the battery is adjacent to the PCB board. A first socket and a second socket are provided at one side of the PCB board, wherein the side of the PCB board is adjacent to the battery. The first electrode pin is inserted and soldered in the first socket, and the second electrode pin is inserted and soldered in the second socket.

Abstract: Proposed are a medical spray head (300) for spraying one or more fluid substances with the use of a compressed gas, a spray device equipped therewith, and a method for using the same. In order to avoid too high a gas pressure, the spray head comprises a pressure relief valve (310) which guides the compressed gas out of the spray head if the gas pressure exceeds a threshold pressure. As a result, the risk of gas embolisms occurring during the use of such a spray head for medical purposes is reduced.

Abstract: Systems and methods are provided for humidifying ventilation gas. Systems and methods may include a nasal interface apparatus for receiving ventilation gas from gas delivery tubing and for humidifying ventilation gas. The nasal interface apparatus may have one or more channels within the nasal interface to deliver gas from a gas delivery circuit to a patient's nose; one or more structures in fluid communication with the one or more channels to direct ventilation gas to the patient's nose; and a hygroscopic material within the nasal interface in the flow path of the ventilation gas.

Abstract: An alignment unit for a laser analyzer that performs measurements on a substance inside a chamber includes a first alignment flange that attaches to the chamber, a second alignment flange that attaches one of a launch unit or detect unit of the laser analyzer to the chamber, an alignment stud for adjusting horizontal and vertical alignment of the second alignment flange, an optical window that keeps the chamber closed when the one of the launch unit or detect unit is removed from the chamber, and a sealing member provided between the second alignment flange and the optical window.

Abstract: A pulmonary drug delivery device having one or more vortexing elements which impart beneficial flow characteristics to an inspiratory air flow carrying a medicament into the patient's lungs.

Abstract: A positive oscillatory expiratory air pressure respiratory therapy device which is adapted to receive a nebulizer for administering aerosolized medicant for selective administration during oscillatory positive expiratory pressure (PEP) therapy.

Abstract: A nebulizer includes a main body unit, an atomization unit, and a breath detection unit, which is a function unit for realizing an additional function of the nebulizer. The main body unit and the atomization unit are separable. The atomization unit includes a storage section for storing the medicinal solution, and an atomizing section for spraying the medicinal solution by atomizing the medicinal solution in the storage section. The main body unit includes a control circuit for performing control to operate the atomizing section. The breath detection unit is attachable between the main body unit and the atomization unit.

Abstract: A method for supplying a mask through which air flows with a regulated degree of humidification (m) is provided. The method may include: providing a water reservoir configured such that the air circulates in contact with the surface of water within the reservoir is charged with humidity; providing a heating device for heating the water in the reservoir by circulating an electric current; measuring an average intensity (Iav) of the current passing through the heating device; and controlling the average intensity (Iav) relative to a reference value (Iavc) to obtain a degree of humidification (m) of the air that is independent of the ambient temperature (Ta). An apparatus for regulating the degree of humidification of air flow, as well as a heating humidifier including such a regulation device, are also provided.

Abstract: An aerosol aspirator has a casing (2) with a mouthpiece (8) and an outside air inlet (52), a generation passage (56, 60, 68) extending from the outside air inlet (52) to the mouthpiece (8), a syringe pump (18) arranged within the casing (2) to deliver a solution to a distributing position (A) in the generation passage in a fixed amount each time it is activated, and a tubular heater (58) disposed downstream of the distributing position (A) and forming a part of the generation passage. When a user sucks at the mouthpiece (8), the solution at the distributing position (A) is transferred from the position (A) into the heater (58), and within the heater, atomized, and then turns into an aerosol by condensing in sucked air flow, and the aerosol thus formed is sucked by the user with the air flow.

Abstract: A liquid tank for an aerosol inhalator has a reservoir channel opening into air at one end thereof and containing flavor solution inside; a supply pipe connecting the other end of the reservoir channel to an inhalation passage of the aerosol inhalator and guiding the flavor solution to the inhalation passage through either one of inhalation pressure in the inhalation passage and capillary action; and an outflow valve located between the other end of the reservoir channel and the supply pipe, for allowing only the flow of the flavor solution running from the reservoir channel towards the supply pipe.

Abstract: A nebulizer is provided that includes an internal medication chamber and a pressurized gas diverter. The internal medication chamber is configured for holding a medication. The pressurized gas diverter includes a diverter orifice.

Abstract: A fluid flow control valve comprises (a) a high pressure region adapted to contain a fluid at its supercritical or nearcritical temperature and pressure conditions and connected via an orifice to a low pressure region, (b) a seat adjacent the orifice, (c) a sealing element positionable against the seat to form a seal between the high pressure region and the low pressure region, and (d) an electrically and/or electronically controlled actuator operable to move the sealing element against and/or away from the seat to allow control of fluid flow from the high pressure region to the low pressure region. In a specific embodiment, the high pressure region contains a fluid at its supercritical or nearcritical temperature and pressure conditions. The valve may be used, for example, to provide very low flow rates, for example, for supercritical fluid chromatography, supercritical fluid extraction, critical point drying, supercritical fluid cleaning, and supercritical fluid separation methods.

Abstract: In a press-type medical nebulizer and a pressing means thereof, the nebulizer includes a medicament container having an intake channel and a medical spray generator. The pressing means includes a base, a pressing element and a switching element. The base has a gas-delivering tube, a gas-releasing hole and a trough. The pressing element comprises an operating arm pivotally connected into the trough and a valve for closing the gas-releasing hole. The switching element is slidingly provided on the operating arm to be selectively engaged into the trough for fixing the operating arm. When the switching element is engaged into the trough, the switching element causes the valve to close the gas-releasing hole, so that the pressurized gas can continuously flow through the gas-delivering tube and enter the intake channel. By this arrangement, the user needs not to press the pressing means repeatedly, which is convenient and labor-saving.

Abstract: A nebulizer includes an insertable container and a securing mechanism for holding the container in the nebulizer such that the container can move back and forth but can not be separated. The securing mechanism is formed by a metal unitary part. The securing mechanism forms a transportation lock for holding the container unmovable in the housing in a delivery state of the nebulizer. The securing mechanism forms a cage which encompasses the container.

Abstract: A nebulizer is proposed which comprises a blocking device for blocking opening of the nebulizer in a tensioned state. The nebulizer comprises preferably an indicator device for indicating a tensioned state of the nebulizer. The nebulizer comprises further a depressible actuator member at a housing part which is detachable from the nebulizer.

Abstract: The present invention is a method for euthanizing animals humanely and painlessly by introducing droplets of liquid anesthesia into a chamber to cause the animal to become anesthetized. Carbon Dioxide is then introduced to induce a death to the animal that substantially meets or exceeds national and international standards for euthanasia.

Abstract: A nebulizer which has an insertable container and a counter device for counting operations of the nebulizer, and is opened for replacing the container. A securing device having locking portions which are forced apart is provided to prevent reconnection of an already used container. The nebulizer has an indicator for showing the current container number and/or symbols indicating the need container replacement. The indicator is driven by the force of an internal spring. The indicator member also controls a lock of the container for locking the container against further actuation. The lock is reset after container replacement.

Abstract: A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.

Abstract: Devices are disclosed that include an elongated member configured to support a delivery tube and maintain a distal end of the tube in a desired position, and to allow the position of the distal end of the tube to be adjusted by a user, and a base configured to support a proximal end of the elongated member. The base includes a chamber configured to receive a medicine cup containing a supply of medicine and position a first end of the medicine cup in fluid communication with a source of compressed gas and a second end of the medicine cup in fluid communication with the delivery tube. These devices may be used, for example, in the delivery of nebulized medicine to a patient, e.g., a child or infant on a bed.

Abstract: The present invention is based on the in vivo demonstration that RSV can be inhibited through intranasal administration of iRNA agents as well as by parenteral administration of such agents. Further, it is shown that effective viral reduction can be achieved with more than one virus being treated concurrently. Based on these findings, the present invention provides general and specific compositions and methods that are useful in reducing RSV mRNA levels, RSV protein levels and viral titers in a subject, e.g., a mammal, such as a human. These findings can be applied to other respiratory viruses.

Abstract: A nasal nebulizer with a main canister for receiving fluid and an insert with a fluid channel includes a contiguous pressurized air supply source. The fluid channel may be a tapered tube overlapping an air exit port in the canister. The fluid channel may also comprise a common bell housing surrounding the air exit port above a base of the insert, which rests within the canister. The insert may include an extension projecting out to the canister and a vertical groove may extend down the fluid channel to a hole in the extension, which upon use helps create a vacuum that pulls in deflected fluid. The main canister includes a convex top surface around the periphery of an opening for a reservoir that receives fluids. The top surface extends downwardly to a generally rectangular opening that connects to the pressurized air supply source.

Abstract: A pre-filled, single-use, disposable medication chamber for use in a medical nebulizer system that delivers a mist of properly sized aerosol particles of medicament to the patient. The nebulizer can be effectively used in conjunction with conventional nebulizer cap, tee and mouthpiece devices that interface with the patient.

Abstract: A delivery device for providing therapeutic gas to the nasal airway of a subject, the delivery device comprising: a nosepiece (21) for fitting to one nostril of the subject; a mouthpiece (23) through which the subject in use exhales and which is fluidly connected to the nosepiece (21); and a scrubber (27) which is operative at least to reduce the concentration of at least one gas from an exhaled breath of the subject as delivered through the mouthpiece (23) and provide a gas flow to the nosepiece (21) which has an increased concentration of at least one other,” therapeutic gas which provides a therapeutic effect.

Abstract: A reservoir and a nebulizer having such a reservoir are proposed. The reservoir comprises a closure for a fluid chamber with a medicament formulation that is formed by two closure members welded together. The closure comprises a particle barrier for preventing the ingress into the fluid chamber of any weld particles that may potentially be formed during the welding of the two closure members. The fluid chamber is preferably broadened in the shape of a beaver tail and is sealed lengthways with an additional strip of material.

Abstract: Systems and methods for neutralizing a solution comprising a compound of interest, comprising: aerosolizing a solution, wherein the solution is a low pH solution and comprises the compound of interest; contacting the aerosolized solution with ammonia vapor, wherein the ammonia vapor neutralizes at least a portion of said aerosolized solution; and removing at least some water from the neutralized aerosolized solution, wherein the neutralized aerosolized solution is at least partially dehydrated.

Abstract: A nebulizer for efficiently and reliably delivering aerosolized fluid to an inhaling patient is disclosed. The nebulizer includes a fixed diverter and a movable fluid orifice or fluid pathway connected with an actuator for responding to an inhalation or a manual actuation and beginning the nebulization process. Also provided is a method of providing nebulization including the steps of moving a fluid orifice or fluid pathway connected to an actuator so that the fluid orifice or fluid pathway reaches a nebulizing position during inhalation.

Abstract: The disclosure describes an aerosolizer with (i) means sized for intranasal or paranasal insertion that produces an aerosol from a material for delivery in close proximity to the upper airways, and (ii) the material comprising one or more proinflammatory cytokine inhibitor(s).

Abstract: The invention provides a method of treating rhinitis. The method comprises administering an effective amount of a danazol compound or a pharmaceutically acceptable salt thereof. The invention also provides a pharmaceutical product formulated for nasal administration. The product comprises a danazol compound or a pharmaceutically acceptable salt thereof.

Abstract: The invention provides a method of treating rhinitis. The method comprises administering an effective amount of a pharmaceutical composition comprising a diketopiperazine with amino acid side chains of aspartic acid and alanine (DA-DKP) formulated for nasal administration. The invention also provides a pharmaceutical product comprising a DA-DKP containing composition.

Abstract: A nebulizer for efficiently and reliably delivering aerosolized fluid to an inhaling patient is disclosed. The nebulizer includes a fluid channel air inlet and fluid channel air inlet valve responsive to either a manual force external of the nebulizer, or a patient's breathing, to begin the nebulization process. Also provided is a method of providing nebulization including the steps of moving a fluid channel air inlet valve against a fluid channel air inlet so that a negative pressure may build up over the fluid in the fluid channel to draw fluid from the fluid reservoir and begin nebulization during inhalation.

Abstract: To deliver a medication and its active ingredients to the esophagus, a nasal irrigator, which is capable of delivering medicated fluid that coats the whole nasal and paranasal sinus cavities, is used. The nasal irrigator forces an aerosol mist of the medicated fluid into the nasal cavity above the inferior turbinate, independent of a user's breathing in. Mucociliary clearance from the nasal cavity then delivers the medication to the throat and it is then topically introduced onto the esophagus over an extended period of time.

Abstract: A medication reservoir is contained within a nebulizer body. An air line includes a distal end within the nebulizer body and venturi nozzle. A medication suction line extends from the medication reservoir to the venturi nozzle through which medication is drawn upward and mixed with air after passing through the venturi nozzle and nebulized for discharge through the nebulizer outlet. A valve is positioned within the air line proximal to the venturi nozzle and normally configured in a closed position until a negative inspiratory pressure is applied by a user to open the valve and allow air through the air line and venturi nozzle from a source of air and draw medication upward through the medication suction line for nebulization and discharge through the nebulizer outlet.

Abstract: A nebulizer kit includes a case body having a compressed air introduction tube in an upper end portion of which a nozzle hole that expels compressed air is formed, a suction channel formation member that forms a suction channel for sucking a liquid toward the upper end portion and that forms an atomizing area in an exit region of the nozzle hole, and a flow channel formation member having an aerosol discharge port. The suction channel has a first suction channel extending upward along an outer circumferential surface of the compressed air introduction tube, and a second suction channel that extends from the first suction channel toward the nozzle hole at a leading end area of the compressed air introduction tube and has a liquid suction port that expels the liquid. An upper sloped surface region that slopes toward the suction channel is provided above the liquid suction port.

Abstract: A dosing device generating a gas flow with an active substance finely dispersed, with a first gas flow channel and with a dosing chamber that can be fitted in the area of the first gas flow channel, and a dosing chamber release mechanism with a separating element. The first gas flow channel and/or a connection between the first gas flow channel and the dosing chamber is blocked when the separating element is in a closed position. The first gas flow channel and/or the connection between the first gas flow channel and the dosing chamber is freed when the separating element is in an open position. A slide guide element can be driven by the under-pressure applied to the mouthpiece. The separating element and/or the slide guide element is provided with a slide element that influences the sliding friction properties.

Abstract: Particular aspects provide novel atomizers for generating particles over a broad range of MMAD size distributions, the eliminating the requirement for an impaction baffle in generating the desired particle sizes. In particular aspects, the atomization means communicates with a remote particle filter member configured and positioned to provide for particle size filtering. In additional aspects, the atomization means communicates with a particle dispersion chamber suitable to impart a desired particle flow pattern to particles within and exiting the dispersion chamber. In further aspects, the atomization means communicates with a nasal, ocular, oral or ‘vicinity’ adapter. The novel devices provide for targeted (e.g., nasal, ocular, oral, local vicinity), systemic, and/or topical delivery of an atomized liquid (e.g., via the nasal cavity, olfactory region, and mouth). Further exemplary aspects relate to aerosolization and delivery of perfume, fragrance, essential oil or cosmeceutical agents and the like.

Abstract: The invention relates to a turbo-inhaler, comprising an active-liquid container (1) holding a liquid having an active ingredient dissolved therein, a nebulizer (2), by means of which liquid can be converted into an aerosol and introduced into a blade housing (3), in which a bounding dome (4) is suspended, the concave side (41) of which is directed at the nebulizer, an exhaust air duct (5), which is connected to the blade housing in the area of the convex side (42) of the bounding dome, and a supply-air guide (6), by means of which supply air can be introduced between the blade housing and the active ingredient, wherein at least one guide blade (7) is placed on the convex side of the bounding dome and spirally extends thereon.

Abstract: A drug delivery device mainly has a housing, which can be easily held and operated. The housing has one end formed with an adjustment seat capable of adjusting a range distance, and the other end connected to a gas pressure control source for providing mainstream and substream gas pressures. Disposed in the housing are a drug delivery pressuring tube, an embedded drug-can connecting seat or an external drug-can connecting seat, a replaceable drug-can container and a gas communication tube. According to this design, the minor liquid drug can be controlled, the drug-can can be replaced and the continuous quantitative injection of drug can be made. Also, all damaged or dirty members of the invention may be disassembled, cleaned or replaced.

Abstract: The disclosure relates to a medicament delivery assembly that has a mouthpiece provided with an air amplifier and a primer source, where the mouthpiece and the air amplifier are each connected to the primer source via an actuatable valve. The air amplifier is also provided with a medicament extraction tube such that when the actuatable valve is opened, the primer source is activated and causes air to flow to the air amplifier. There is also described a method of administering a medicament using such a medicament delivery assembly.

Abstract: A nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a delivery unit for delivering a flow entraining a substance to one nostril of a subject, the delivery unit including a nosepiece for fitting to a nostril of the subject; and a flow resistor unit for fitting to the other nostril of the subject, the flow resistor unit including a progressive resistor for progressively providing an increasing flow resistance to the delivered flow.

Abstract: A nebulizer includes a venturi nozzle positioned at the outlet end of an air line and oriented horizontally and located within a patient's oral cavity when in use. A canister port is located at the inlet end of the air line and receives a gas canister. A valve is actuable to allow a metered flow of gas at a predetermined pressure and time to flow from the gas canister through the air line and venturi nozzle. A medication receiver is carried by the nebulizer body proximal to the venturi nozzle. A suction line extends from the venturi nozzle to the medication receiver and draws medication upward from a medication container and mixes it with air passing through the venturi nozzle and nebulizes the medication.

Abstract: An atomizer has a venturi nozzle positioned at an outlet end of an air line and has a discharge end and is oriented horizontally when in use and forms a mixing chamber at its discharge end. A valve is positioned at a canister port and actuable to allow a metered flow of gas at a predetermined pressure and time through the air line and venturi nozzle. A suction line extends from the venturi nozzle and mixing chamber to a medication receiver and draws medication upward and mixes it with gas passing through the venturi nozzle into the mixing chamber and atomizes the medication into a mist.

Abstract: A nebulizer includes a nebulizer body having an air channel section, medication reservoir and nebulizer outlet. An air line has an inlet at one end and extends through the air channel section and has a venturi nozzle oriented horizontally when in use and an outlet and configured to form a low pressure mixing chamber. The air line provides a pulsed flow of gas between the inlet and outlet end. The venturi nozzle and medication reservoir are received within an oral cavity of a patient when in use. A primary suction line extends from the medication reservoir to the low pressure mixing chamber through which medication is drawn upward and mixed with gas passing through the venturi nozzle and nebulized for pulsed discharge through the nebulizer outlet during nebulization.

Abstract: A reservoir for a nebulizer, and a nebulizer with a reservoir in which, to avoid undesirable rises in pressure, a fluid chamber of the reservoir is pre-collapsed and filled with an initial amount of fluid which is less than the maximum volume of the fluid chamber. Preferably, before being filled, the fluid chamber is compressed and/or expanded by means of gas to a defined volume which is less than the maximum volume of the fluid chamber.

Abstract: A medication reservoir is formed in the lower portion of a nebulizer body and covered to form an enclosed medication reservoir. A nozzle assembly is supported by a reservoir cover and includes an air line having an inlet at one end and an outlet and a venturi nozzle and venturi outlet. The air line, venturi nozzle and discharge outlet are horizontally oriented when in use and the venturi nozzle is located within a patient's oral cavity when the nebulizer is in use. Medication is drawn upward through a suction line and mixed with air passing through the venturi nozzle and nebulized for discharge through the nebulizer outlet. The venturi nozzle and suction line are formed together and replaceable as one unit.

Abstract: The present application discloses devices and methods for delivering a therapeutic compound to the olfactory epithelium of an animal or human. The device having one or more channels for imparting a circumferential and axial velocity to the discharged fluid, and an outlet that discharges an aerosol spray having a circumferential and axial velocity as it enters the nasal cavity of a user. The device is designed to displace the air in the upper nasal cavity in order to specifically deposit a therapeutic agent on the olfactory epithelium while minimizing pressure and discomfort experienced by the user.