Devices Placed Entirely Within Body And Means Used Therewith (e.g., Magnetic Implant Locator) Patents (Class 128/899)
  • Publication number: 20040176685
    Abstract: A capsule medical apparatus for medical actions such as examination and treatment in the body detects by a sensor or the like whether it is just being evacuated from the body or it has already been evacuated. Upon detecting the capsule medical apparatus is positioned in the large intestine or it has already been evacuated, the capsule medical apparatus notifies such information in association with the detection.
    Type: Application
    Filed: March 1, 2004
    Publication date: September 9, 2004
    Applicant: OLYMPUS CORPORATION
    Inventors: Hironobu Takizawa, Takeshi Yokoi, Akira Kikuchi
  • Publication number: 20040176684
    Abstract: An endoscope pretest capsule has approximately the same shape and weight as a capsule-type endoscope and is brought into the body before applying the capsule-type endoscope, and it includes barium sulfate which is a radiopaque substance (or a microcapsule wrapping a radiopaque substance) in a capsule body formed by a material having main components such as chitosan, and has an enteric coat for dissolving after elapse of a predetermined time provided on the surface side thereof. It is possible, by having the pretest capsule swallowed by an examinee in advance, to grasp passage conditions of the capsule-type endoscope in the body and secure good discharge out of the body because it dissolves in the case of remaining in the body for the predetermined time or longer.
    Type: Application
    Filed: February 20, 2004
    Publication date: September 9, 2004
    Applicants: Fuji Photo Optical Co., Ltd., Masafumi TABUCHI
    Inventors: Masafumi Tabuchi, Shinji Takeuchi, Shuichi Yamataka
  • Publication number: 20040176683
    Abstract: Methods and apparatus for tracking insertion depth of endoscopes are described herein. One method for determining endoscopic insertion depth within a body is to utilize a fully instrumented endoscope configured to determine its depth of insertion. Another method uses a datum device which interacts with the endoscope to determine how much of the endoscope has passed by a reference boundary. A fully instrumented endoscope can poll the status of the entire endoscope and then determine its position relative to anatomical boundaries, e.g., the anus. The polled information is obtained by sensors or transponders located along the length of the endoscope. When using an endoscope with a datum, the datum can read positional information by polling the status of sensors or transponders located along the body of the endoscope as the endoscope passes through the anus. The datum can be affixed to the patient or to another fixed reference point.
    Type: Application
    Filed: March 7, 2003
    Publication date: September 9, 2004
    Inventors: Katherine Whitin, Robert M. Ohline, Amir Belson, Alex Roth, Lawrence W. Arne
  • Publication number: 20040173222
    Abstract: A magnetic pellet for use in treating a patient's congestive heart includes a contact portion and a plurality of wings. Each wing has a distal end portion hingedly connected to the contact portion and a proximal end portion. The proximal end portions bend toward each other when an electromagnetic field is applied to the pellet. A method of inserting the pellets into a myocardial wall of a heart includes supplying an electromagnetic field to the pellet attached to a distal end of an electromagnetic rod positioned within a delivery catheter, positioning the magnetic pellet at a target area on the myocardial wall; using an injection syringe, positioned at a proximal end of the catheter, to force the pellet into the myocardial wall; and removing the electromagnetic field previously supplied to the pellet and thereby causing the spring-wings to open.
    Type: Application
    Filed: April 26, 2004
    Publication date: September 9, 2004
    Inventor: Young D. Kim
  • Patent number: 6786219
    Abstract: A method of navigating a medical device having a changeable magnetic moment within an operating region within a patient, the method includes applying a navigating magnetic field to the operating region with an external source magnet, and changing the direction of the magnetic moment in the medical device to change the orientation of the medical device in a selected direction within the operating region. The magnet moment of the medical device can be created by one or more electromagnet coils, in which case the magnetic moment can be changed by changing the current to the coil. Alternatively, the magnetic moment of the medical device can be created by one or more permanent magnets, in which case the magnetic moment can be changed by mechanically or magnetically manipulating the permanent magnet.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: September 7, 2004
    Assignee: Stereotaxis, Inc.
    Inventors: Jeffrey M. Garibaldi, Roger N. Hastings
  • Publication number: 20040168692
    Abstract: This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Other localization wire embodiments of the invention are disclosed in which the tissue volume may be penetrated by a portion of the device.
    Type: Application
    Filed: March 10, 2004
    Publication date: September 2, 2004
    Inventors: Thomas J. Fogarty, David B. Willis, Thomas A. Howell, George D. Hermann, Peter M. Wilson, Elizabeth M. Bush, Steven W. Kim, Roman Turovskiy
  • Patent number: 6783499
    Abstract: An implantable medical device comprises a housing having a proximal end and a distal end and a longitudinal axis. A first set of anchoring members are operatively connected to the proximal end of the housing. A second set of anchoring members are operatively connected to the distal end of the housing. The first set of anchoring members and the second set of anchoring members are movable between a collapsed position and a deployed position. The collapsed position is defined as a position whereby the first set of anchoring members and the second set of anchoring members are substantially parallel to the longitudinal axis of the housing. The deployed position is defined as a position whereby the first set of anchoring members and the second set of anchoring members are substantially perpendicular to the longitudinal axis of the housing.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: August 31, 2004
    Assignee: Biosense, Inc.
    Inventor: Yitzhack Schwartz
  • Patent number: 6777623
    Abstract: The apparatus and method is provided that employs a “radiopaque” object to count and account for surgical sponges in an operating room. A radiopaque object is embedded in surgical sponges so that a scanning device can detect and count a large number of the sponges within a container. The container is designed to minimize contact with the sponges by humans. In addition, a surgical team can insure that no surgical sponge is left in a patient without performing the messy and time-consuming job of individually counting sponges as they are entered and disposed of from the surgical site.
    Type: Grant
    Filed: April 17, 2002
    Date of Patent: August 17, 2004
    Inventor: M. Daniel Ballard
  • Patent number: 6776165
    Abstract: This invention discloses such a convenient navigation system and navigatable capsules which are useful for remote-controlled imaging, biopsy and programmable drug release within the body of an animal. The components of the system comprise a capsule dimensioned and shaped to move within the body. An anisotropic magnetic component is mechanically coupled to the capsule to move or orient the body in relation to an applied magnetic field, and a magnetic field generating system external of the body generates a three dimensionally oriented magnetic field within the body to move or orient capsule.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: August 17, 2004
    Assignee: The Regents of the University of California
    Inventor: Sungho Jin
  • Publication number: 20040158144
    Abstract: An NMR probe, includes a permanent magnet generating a static magnetic gradient field (B0), and a pair of RF coils enclosing the permanent magnet for receiving RF current to generate a varying magnetic field (B1) perpendicular to the static magnetic gradient field (B0). The pair of RF coils are orthogonally located with respect to each other such that the gradient magnetic field (B1) is rotatable about the longitudinal axis of the probe according to the current through one RF coil relative to that through the other RF coil. As described, the NMR probe is particularly useful for intra-luminal imaging.
    Type: Application
    Filed: February 3, 2004
    Publication date: August 12, 2004
    Applicant: TopShooter Medical IMRI Inc.
    Inventors: Hanan Keren, Avram B. Simon
  • Publication number: 20040158142
    Abstract: A magnetically navigable catheter includes a sheath having a proximal end and a distal end, and an extension member having a proximal end and a distal end, slidably mounted in the sheath so that the distal end portion of the extension member telescopes from the distal end of the sheath. The distal end portion of the extension member being relatively more flexible than the distal end of the sheath. There may be one or more electrodes on the distal end of the extension member. There is also at least one magnet, and preferably more than one magnet, on the distal end portion of the extension member to allow the distal end of extension member to be oriented by the application of an externally applied magnetic field.
    Type: Application
    Filed: February 9, 2004
    Publication date: August 12, 2004
    Inventors: Andrew F. Hall, Walter M. Blume
  • Publication number: 20040152972
    Abstract: A tunable implant, system, and method enables a tunable implant to be adjusted within a patient. The tunable implant includes a securing mechanism to secure the implant in the patient, a actuation portion that enables the implant to move and an adjustment portion that permits adjustment of the implant after the implant has been positioned within the patient. The method of adjusting the tunable implant includes analyzing the operation of the implant, determining if any adjustments are necessary and adjusting the implant to improve implant performance. The implant system includes both the tunable implant and a telemetric system that is operable to telemetrically receive data from the tunable implant where the data is used to determine if adjustment of the tunable implant is necessary. The system also includes an instrument assembly that is used for performing spinal surgery where the instrument assembly includes a mounting platform and a jig.
    Type: Application
    Filed: April 25, 2003
    Publication date: August 5, 2004
    Inventor: Mark Hunter
  • Publication number: 20040147801
    Abstract: Plural (at least two) magnetic devices are implanted in a patient so that magnetic interaction between those devices modifies the patient's body in one or more respects (e.g., by modifying the shape and/or performance of some part of the body) Prior to implantation, a location in the body may be marked for later reference during the implantation. The magnetism of one or more of the magnetic devices may be changed in vivo after implantation. One or more of the implanted devices may be subsequently removed from the patient if desired. Use of the magnetic devices inside tissue conduits (e.g., as a treatment for GERD) is especially considered by way of illustration.
    Type: Application
    Filed: July 1, 2003
    Publication date: July 29, 2004
    Applicant: Torax Medical, Inc.
    Inventors: Chad J. Kugler, Jerome K. Grudem
  • Publication number: 20040143183
    Abstract: The present invention relates to a device for detecting a position and an orientation of an insertion portion of a medical insertion tool which is inserted inside a body cavity, from the outside, and a detecting method therefor. An object of the present invention can achieve a downsized and lightweight insertion portion so as to be smoothly and easily insertable into even a narrow body cavity such as a blood vessel inside a skull, without having a bad influence on a vital tissue. Moreover, another object thereof is to make it possible to detect the three-dimensional position and orientation of the insertion tool very accurately while minimizing a noise. According to the present invention, a permanent magnet or a ferromagnetic body 4 is attached to an insertion portion 2 of a catheter 1 as an example of the medical insertion tool, which is inserted into the body cavity.
    Type: Application
    Filed: October 29, 2003
    Publication date: July 22, 2004
    Applicants: Uchihashi Estec Co., Ltd., Ken Ikeuchi
    Inventors: Kazumi Toyoda, Tomoki Okazaki, Ken Ikeuchi
  • Publication number: 20040143260
    Abstract: A method for ablation in which a portion of atrial tissue around the pulmonary veins of the heart is ablated by a first elongated ablation component and a second elongated ablation component movable relative to the first ablation component and having means for magnetically attracting the first and second components toward one another. The magnetic means draw the first and second components toward one another to compress the atrial tissue therebetween, along the length of the first and second components and thereby position the device for ablation of the tissue.
    Type: Application
    Filed: January 13, 2004
    Publication date: July 22, 2004
    Inventor: David E. Francischelli
  • Publication number: 20040138555
    Abstract: Systems and methods for locating and defining a target location within a human body. The system can include at least one marker, a probe, and a detector for use in locating the markers by providing information to a surgeon that is representative of changes in proximity between the probe and the marker. The marker can have various detection characteristics, e.g., gamma radiation, that are detectable by an associated probe and detector. The tissue volume is removed by manipulating a cutting tool based on the proximity information provided by the detector, which can be used by the surgeon to define the boundary of the tissue volume. The systems and methods of the invention are particularly useful in locating and then removing a tissue volume or other target location from amorphous, pliable tissue (e.g., breast tissue) or other body parts.
    Type: Application
    Filed: December 23, 2003
    Publication date: July 15, 2004
    Inventors: David Krag, Eric Meier, Steve Dimmer, Duane Durbin, Trevor Moody, Fred Silverstein, Rosemary Harry, Richard Frecksa, Amy Kinsella, Jon Gilbert
  • Publication number: 20040138552
    Abstract: A device for mobilizing, rotating and maneuvering an in vivo vehicle introduced into a subject by extracorporeal devices which control the position and motion of such a vehicle by detection and modulation of the strength and direction of the electromagnetic field vector of the vehicle. This invention employs a series of pulses, with specific characteristics over time, to induce magnetic field changes. The changes that result from the vehicle movement are measured and used to calculate the location and movement of the vehicle. A system and method for controlling the movement of the vehicle are also provided.
    Type: Application
    Filed: October 16, 2003
    Publication date: July 15, 2004
    Inventors: Alex Harel, Uzi Dan, Ehud Katzenelson, Zvi Raviv
  • Publication number: 20040129279
    Abstract: Externally detectable electronic article surveillance markers are attached to surgical implements, such as sponges and surgical instruments, appointed for use in a surgical wound. The attachment mechanism facilitates detection by an external interrogating field before the wound has been closed and the patient has left the operating table. The markers are responsive to the imposition of an interrogating field produced by an electronic article surveillance system. Markers contain one or more magnetomechanically responsive elements that are urged into mechanical resonance by the interrogating field. The ring-down of the resonance and the associated dipolar electromagnetic field provide a signal-identifying characteristic detected by a detection system. Upon detection, an audible or visible signal is triggered to alert relevant medical personnel to the need for follow-up care and removal of the offending item. The resonance occurs at a frequency ranging from about 70 to 300 kHz.
    Type: Application
    Filed: November 26, 2003
    Publication date: July 8, 2004
    Inventors: Carl E. Fabian, Philip M. Anderson, Gordon E. Fish
  • Publication number: 20040127787
    Abstract: A leadless marker for localizing the position of a target within a patient. In one embodiment, the marker includes a casing, a resonating circuit, and a ferromagnetic element. The casing is configured to be positioned at a selected location relative to a target site in the patient; the casing, for example, can be configured to be permanently or semi-permanently implanted into the patient. The resonating circuit has an inductor within the casing comprising a plurality of windings of a conductor, but it does not have external electrical lead lines extending through the casing. The ferromagnetic element is at least partially within the inductor. The ferromagnetic element has a volume such that when the marker is in an imaging magnetic field having a field strength of 1.5 T and a gradient of 3 T/m, then the force exerted on the marker by the imaging magnetic field is not greater than gravitational force exerted on the marker.
    Type: Application
    Filed: December 30, 2002
    Publication date: July 1, 2004
    Inventors: Steven C. Dimmer, Eric Hadford
  • Publication number: 20040123871
    Abstract: Embodiments of the invention are directed to an apparatus for use in a system that senses an excitable wireless target capable of being implanted in a body or tissue. The apparatus includes multiple electromagnetic field sensors arranged approximately in a common plane, and multiple sense signal output paths coupled to the sensors. Each one of the sensors and corresponding output paths is configured to provide an output signal representing at least a portion of an electromagnetic field provided by the marker, where the output signal is proportional to a component of the field at the sensor, where that component is substantially perpendicular to the plane. Various other configurations regarding this apparatus, as well as the overall system and methods of exciting and receiving signals from wireless markers, are also disclosed.
    Type: Application
    Filed: March 4, 2003
    Publication date: July 1, 2004
    Inventors: J. Nelson Wright, Laurence J. Newell
  • Patent number: 6755199
    Abstract: A sensing probe assembly and method for locating a magnetic field emitted by an implanted medical device. The assembly has a housing containing a magnetic field sensor circuit having an indicator light and a magnetic switch. The assembly further has a structure for marking the location of the magnetic field. The method utilizes a marking system whereby at least four points forming at least two perpendicularly intersecting line segments are located and marked above the magnetic field. The intersection is then used as a reference point for performing a medical procedure on the implanted medical device.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: June 29, 2004
    Assignee: PMT Corporation
    Inventors: Carey D. Rehder, Jason P. Porter, Deron J. Singer
  • Patent number: 6755791
    Abstract: An ultrasonic diagnostic apparatus includes one transmitting coil arranged in the longitudinal direction of an endoscope inserting portion in an ultrasonic endoscope, and another transmitting coil for detecting the position and the direction, which detects the position and the direction of a tomographic plane when forming a tomogram at a distal end portion of an inserting portion by an ultrasonic vibrator. A coil energizing signal is applied to both the transmitting coils so as to generate a magnetic field. The magnetic field is detected by receiving coils. A position and direction calculating circuit detects positional data of the one transmitting coil and positional and directional data of the other transmitting coil. The calculated data is transmitted to an auxiliary-image forming circuit which forms an image of an inserting shape and an auxiliary image indicating the position and the direction of the tomographic plane.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: June 29, 2004
    Assignee: Olympus Corporation
    Inventor: Tomonao Kawashima
  • Patent number: 6757557
    Abstract: Methods and apparatus are provided for locating the position, preferably in three dimensions, of a sensor by generating magnetic fields which are detected at the sensor. The magnetic fields are generated from a plurality of locations and, in one embodiment of the invention, enable both the orientation and location of a single coil sensor to be determined. The present invention thus finds application in many areas where the use of prior art sensors comprising two or more mutually perpendicular coils is inappropriate.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: June 29, 2004
    Assignee: British Telecommunications
    Inventors: John Stuart Bladen, Alan Patrick Anderson
  • Patent number: 6752154
    Abstract: This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Other localization wire embodiments of the invention are disclosed in which the tissue volume may be penetrated by a portion of the device.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: June 22, 2004
    Inventors: Thomas J. Fogarty, David B. Willis, Thomas A. Howell, George D. Hermann, Peter M. Wilson, Elizabeth M. Bush, Steven W. Kim, Roman Turovskiy
  • Patent number: 6752155
    Abstract: Implantable medical device telemetry is provided between an implantable medical device and an external communication device. The implantable medical device includes a device transmitter and/or a device receiver. The external communication device includes a moveable communication head including an antenna therein connected to at least one of an external transmitter and/or an external receiver for communication with the device transmitter and/or the device receiver of the implantable medical device. A user moves the moveable head apparatus relative to the implantable medical device. Tactile feedback is provided to the user via the moveable head apparatus upon movement of the moveable head apparatus to a position where valid telemetry can be performed.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: June 22, 2004
    Assignee: Medtronic, Inc.
    Inventor: Michael D. Behm
  • Patent number: 6748954
    Abstract: A method for drug delivery and polymer matrix suited to the method are disclosed. The polymer matrix has reversibly bound thereto a drug or combination of drugs, and is capable of releasing the drug or combination of drugs in response to mechanical stimulation of the polymer matrix. According to the method of this invention, such a polymer matrix is delivered to an in vivo locus, for example the site of a wound, trauma, etc., and mechanical stimulation of said polymer matrix is effected in vivo, thereby releasing the drug or combination of drugs in the area of the in vivo locus.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: June 15, 2004
    Assignee: The Regents of The University of Michigan
    Inventors: Kuen Yong Lee, David J. Mooney
  • Patent number: 6746404
    Abstract: A method for implanting a medical device between tissue comprises the steps of providing a catheter having a body and a distal end thereof wherein the catheter includes an implantable device comprising a housing having a proximal end and a distal end and a longitudinal axis. The implantable device further includes a first set of anchoring members operatively connected to the proximal end of the housing and a second set of anchoring members operatively connected to the distal end of the housing. Both sets of anchoring members are movable between a collapsed position and a deployed position. Each set of anchoring members includes ring members connected to a housing of the device. Further steps of the method include inserting the distal end of the catheter into tissue and disposing the medical device at least partially from the distal end of the catheter.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: June 8, 2004
    Assignee: Biosense, Inc.
    Inventor: Yitzhack Schwartz
  • Patent number: 6747539
    Abstract: A patient-shielding and coil system, including a coil wire electrically coupled to a source of electrical current, an electrically conductive surface, insulation material situated between the coil wire and the conductive surface, and a drain wire connected to the conductive surface and forming a capacitive current loop with respect to the source.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: June 8, 2004
    Inventor: Michael A. Martinelli
  • Patent number: 6748258
    Abstract: Various methods and devices for treating a patient who has lost, or is at risk of losing cardiac function by cardiac ischemia are disclosed. Treatment includes first imaging a patient's heart, or a portion thereof, to identify underperfused regions of cardiac muscle, and a source of oxygenated blood that is proximate to the underperfused region. Between the underperfused regions and the oxygenated blood source, a target area is selected where thermal or mechanical injury is introduced, and optionally reintroduced, to convert initial capillary blush, resulting from the injury.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: June 8, 2004
    Assignee: SciMed Life Systems, Inc.
    Inventors: Richard L. Mueller, U. Hiram Chee
  • Patent number: 6748255
    Abstract: An improved basket catheter is provided that is particularly useful for mapping the heart. The catheter comprises an elongated catheter body having proximal and distal ends and at least one lumen therethrough. A basket-shaped electrode assembly is mounted at the distal end of the catheter body. The basket assembly has proximal and distal ends and comprises a plurality of spines connected at their proximal and distal ends. Each spine comprises at least one electrode. The basket assembly has an expanded arrangement wherein the spines bow radially outwardly and a collapsed arrangement wherein the spines are arranged generally along the axis of the catheter body. The catheter further comprises a distal location sensor mounted at or near the distal end of the basket-shaped electrode assembly and a proximal location sensor mounted at or near the proximal end of the basket-shaped electrode assembly.
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: June 8, 2004
    Assignee: Biosense Webster, Inc.
    Inventors: Kristine B. Fuimaono, Maria G. Rangel, Dipen Shah
  • Publication number: 20040103906
    Abstract: A device configured for implanting beneath a patient's skin for the purpose of tissue, e.g., nerve or muscle, stimulation and/or parameter monitoring and/or data communication. Devices in accordance with the invention are comprised of a sealed housing, typically having an axial dimension of less than 60 mm and a lateral dimension of less than 6 mm, having a non-circular, e.g., an oval or polygon shaped, cross-section containing a power source for powering electronic circuitry within including a controller, an address storage means, a data signal receiver and an input/output transducer. When used as a stimulator, such a device is useful in a wide variety of applications to stimulate nerves and associated neural pathways. Alternatively, devices of the present invention are configurable to monitor a biological parameter. Furthermore, a placement structure is shown for facilitating placement of the implantable device proximate to neural/muscular tissue.
    Type: Application
    Filed: November 21, 2003
    Publication date: June 3, 2004
    Inventors: Joseph H. Schulman, Robert Dan Dell, John C. Gord
  • Patent number: 6739342
    Abstract: A new device for therapeutic influence, change, decomposition of various biological structures in vivo or in vitro by means of an externally applied alternating magnetic gradient field is described.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: May 25, 2004
    Assignee: European Institute of Science AB
    Inventors: Sarah Fredriksson, Dario Kriz
  • Patent number: 6741882
    Abstract: The invention relates to an MR device with apparatus for localizing and/or visualizing a medical instrument inserted into an object to be examined. In order to construct such a device in a more economical and more reliable manner, according to the invention, the medical instrument is provided with a magnet device which is controllable by a control unit in such a manner that information concerning the position of the magnet device in MR data sets can be specifically changed. The invention also relates to a corresponding MR method.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: May 25, 2004
    Assignee: Koninklijke Philips Electronics N.V.
    Inventors: Tobias Schäffter, Steffen Weiss
  • Patent number: 6729336
    Abstract: A medical device is described that can be used to detect in stent restenosis. This invention consists of a stent of current or modified technology, an electromagnetic wave transmitter to excite the stent and an acoustic sensor to detect stent acoustic oscillations.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: May 4, 2004
    Assignee: Pearl Technology Holdings, LLC
    Inventors: Luiz B. Da Silva, Victor C. Esch, Alexander M. Rubenchik, Jonathan Hares, Joseph D. Kilkenny, Gilbert W. Collins, Paul J. Weber
  • Patent number: 6722371
    Abstract: This invention is an improved tissue localizing device for fixedly yet removably marking a volume of tissue containing a suspect region for excision. This invention also encompasses methods for deployment of the localizing device and its excision along with the marked tissue volume. At least one locator element is deployed into tissue and assumes a predetermined curvilinear shape to define a tissue border containing a suspect tissue region along a path. The locator element path preferably encompasses the distalmost portion of the tissue volume without penetrating that volume. Multiple locator elements may be deployed to further define the tissue volume along additional paths defining the tissue volume border that do not penetrate the volume. Other localization wire embodiments of the invention are disclosed in which the tissue volume may be penetrated by a portion of the device.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: April 20, 2004
    Inventors: Thomas J. Fogarty, David B. Willis, Thomas A. Howell, George D. Hermann, Peter M. Wilson, M. Elizabeth Bush
  • Patent number: 6718196
    Abstract: A system with multimodality instrument for tissue identification includes a computer-controlled motor driven heuristic probe with a multisensory tip. For neurosurgical applications, the instrument is mounted on a stereotactic frame for the probe to penetrate the brain in a precisely controlled fashion. The resistance of the brain tissue being penetrated is continually monitored by a miniaturized strain gauge attached to the probe tip. Other modality sensors may be mounted near the probe tip to provide real-time tissue characterizations and the ability to detect the proximity of blood vessels, thus eliminating errors normally associated with registration of pre-operative scans, tissue swelling, elastic tissue deformation, human judgement, etc., and rendering surgical procedures safer, more accurate, and efficient. A neural network program adaptively learns the information on resistance and other characteristic features of normal brain tissue during the surgery and provides near real-time modeling.
    Type: Grant
    Filed: August 28, 2000
    Date of Patent: April 6, 2004
    Assignee: The United States of America as represented by the National Aeronautics and Space Administration
    Inventors: Robert W. Mah, Russell J. Andrews
  • Patent number: 6712782
    Abstract: A brachytherapy apparatus is composed of a tubular needle with forwardly protruding cutting edges at its tip, a holder supporting the needle and a driver for electromechanically causing the needle to undergo a continuous or oscillatory rotary motion around its axis and/or a reciprocating linear motion in the longitudinal direction such that its front opening at its tip can reliably reach a specified position inside a patient's tissue without being deflected or bowing when it encounters an obstruction such as a calcification or a small bone. Such motions may be provided by a piezoelectric hammer and a piezoelectric tamper. After the needle is thus correctly positioned, a brachytherapy device such as a radioactive seed or a reflector may be pushed through and out of the needle by means of a pusher as the needle is retracted to leave a track inside the tissue. A quickly hardening liquid may be thereafter injected through the needle to immobilize the deposited brachytherapy device.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: March 30, 2004
    Assignee: Varian Medical Systems Technologies, Inc.
    Inventor: John C. Ford
  • Publication number: 20040055610
    Abstract: An apparatus is disclosed for detecting a wireless energy receiving device subcutaneously implanted in a patient's body to enable accurate positioning of a wireless energy transmission device outside the patient's body relative to the energy receiving device. Also disclosed is a method for detecting the wireless energy receiving device whereby an energy transmission device can be positioned to efficiently transmit wireless energy to the implanted energy receiving device. The apparatus includes a magnetic device that is subcutaneously implanted in the patient adjacent to the energy receiving device to emit a local magnetic field through the patient's skin adjacent to the energy receiving device. A magnetic detector movable externally along the patient's body is capable of detecting the local magnetic field emitted by the magnetic device. This allows the energy transmission device to be located for the efficient transmission of wireless energy to the implanted energy receiving device.
    Type: Application
    Filed: September 25, 2002
    Publication date: March 25, 2004
    Inventor: Peter Forsell
  • Patent number: 6711423
    Abstract: An optical-based sensor for detecting the presence or amount of an analyte using both indicator and reference channels. The sensor has a sensor body with a source of radiation embedded therein. Radiation emitted by the source interacts with indicator membrane indicator molecules proximate the surface of the body. At least one optical characteristic of these indicator molecules varies with analyte concentration. For example, the level of fluorescence of fluorescent indicator molecules or the amount of light absorbed by light-absorbing indicator molecules can vary as a function of analyte concentration. In addition, radiation emitted by the source also interacts with reference membrane indicator molecules proximate the surface of the body. Radiation (e.g., light) emitted or reflected by these indicator molecules enters and is internally reflected in the sensor body.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: March 23, 2004
    Assignee: Sensors for Medicine and Science, Inc.
    Inventor: Arthur E. Colvin, Jr.
  • Publication number: 20040050395
    Abstract: A magnetic anchor remote guidance system includes an engagement member which engages with a body portion in a patient's body; a magnetic anchor made of a magnetic material, connected to the engagement member; and a magnetic anchor guide device which is disposed out of the patient's body and which produces a magnetic field to power the magnetic anchor. The body portion engaged by the engagement member is raised by supplying power to the magnetic anchor via the magnetic field produced by the magnetic anchor guide device.
    Type: Application
    Filed: September 11, 2003
    Publication date: March 18, 2004
    Applicants: PENTAX Corporation, National Cancer Center, Tamakawa Co., Ltd.
    Inventors: Hirohisa Ueda, Kunitoshi Ikeda, Tadao Kakizoe, Toshiaki Kobayashi, Takuji Gotoda, Katsunori Tamakawa
  • Publication number: 20040050394
    Abstract: This invention discloses such a convenient navigation system and navigatable capsules which are useful for remote-controlled imaging, biopsy and programmable drug release within the body of an animal. The components of the system comprise a capsule dimensioned and shaped to move within the body. An anisotropic magnetic component is mechanically coupled to the capsule to move or orient the body in relation to an applied magnetic field, and a magnetic field generating system external of the body generates a three dimensionally oriented magnetic field within the body to move or orient capsule.
    Type: Application
    Filed: September 12, 2002
    Publication date: March 18, 2004
    Inventor: Sungho Jin
  • Patent number: 6704594
    Abstract: An imaging probe and method and an MRI system utilizing the same are presented. The probe comprises first and second magnetic field sources, and a receiver of NMR signals. The first magnetic field source creates a primary, substantially non-homogeneous, static magnetic field in a region of interest in a medium outside the probe. The second magnetic field source creates an external time-varying magnetic field, which when being applied to the region of the static magnetic field, is capable of exciting nuclei in an extended sub-region of this region and generating the NMR signals.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: March 9, 2004
    Assignee: TopSpin Medical (Israel) Limited
    Inventors: Aharon Blank, Gil Alexandrowicz, Erez Golan
  • Patent number: 6699200
    Abstract: A medical device for multi-vector sensing of cardiac depolarization signals is disclosed. Specialized algorithm is implemented to enhance multi-vector electrode sensing. Further a geometric shape is optimized to enable space-volume efficiencies for deployment and navigation of the medical device for implant in a patient.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: March 2, 2004
    Assignee: Medtronic, Inc.
    Inventors: Jian Cao, Brian B. Lee, Spencer R. Hurd
  • Patent number: 6698433
    Abstract: A system and method for bracketing a tissue volume (22) and later locating the bracketed tissue volume. The system includes a plurality of markers (30) and a probe (32) and detector (34) for use in locating the markers by providing information usable by a surgeon that is representative of changes in proximity between the probe and the plurality of markers. The markers have various detection characteristics, e.g., they transmit gamma rays, that are detectable by an associated probe and detector. The tissue volume is removed by manipulating a cutting tool based on the proximity information provided by the detector which can be used by the surgeon to define the boundary of the tissue volume. A two-part cutting tool (200) is provided for removing the tissue volume, and a tissue anchor (300) is provided for stabilizing the tissue during removal. The system and method of the invention are particularly useful in bracketing and then removing a tissue volume from amorphous, pliable tissue such as breast tissue.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: March 2, 2004
    Assignee: Calypso Medical Technologies, Inc.
    Inventor: David N. Krag
  • Patent number: 6695793
    Abstract: An improved guide catheter provides a distal tip with one or more members that assist a surgeon with locating and inserting the guide catheter through the ostium in the wall of the right atrium that leads to the coronary sinus of the heart. The guide catheter is used to implant a cardiac lead so that its electrodes are positioned in the vasculature associated with the left side of the heart.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: February 24, 2004
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Lawrence Brennan, Fozan El-Nounou
  • Patent number: 6694184
    Abstract: A method and assembly for selectively actuating features of implanted medical devices with a magneto-static field. The method includes selectively exposing the implanted device to a static magnetic field source, selectively shielding the magnetic field source, and distancing the shielded magnetic field source from the medical device. One version of the assembly includes a permanent magnet and a displaceable shield assembly that shields the magnetic field generated by the magnet in one configuration and is displaceable to a second configuration wherein the magnetic field is at least partially exposed. In another version, the assembly is an electromagnet that can be selectively activated and deactivated. The electromagnet generates minimal magnet field when it is off.
    Type: Grant
    Filed: January 9, 2001
    Date of Patent: February 17, 2004
    Assignee: Pacesetter, Inc.
    Inventors: Armando M. Cappa, J. Kelly Fox, Paul A. Levine, Matthew Whitlock, James B. Hamilton
  • Publication number: 20040030244
    Abstract: A method of navigating a magnet-tipped distal end of an elongate medical device through the body includes providing an image display of the part of the body through which the medical device is being navigated and using the display to input the desired path of the medical device by identifying points on the desired path on the display. The magnetic field needed to orient the end of the medical device in the direction of the desired path as indicated on the display is then determined. In one embodiment where only points on the desired path are identified, the field direction is the direction indicated by the points on the desired path.
    Type: Application
    Filed: February 18, 2003
    Publication date: February 12, 2004
    Inventors: Jeffrey M. Garibaldi, Rogers C. Ritter, Gerard H. Epplin, Walter M. Blume
  • Patent number: 6682490
    Abstract: An apparatus (10) utilizes microelectricalmechanical systems (MEMS) technology to monitor a condition in a body cavity (28). The apparatus (10) comprises at least one sensor (42) for insertion into the body cavity. The sensor (42) generates a signal in response to a condition inside the body cavity (28). At least one telemetric device (44) is operatively coupled with the sensor (42). The telemetric device (44) is operable to receive the signal from the sensor (42) and to transmit an electromagnetic signal dependent upon the signal. The telemetric device (44) includes at least one coil member (82) extending from the telemetric device. The coil member (82) engages the body cavity (28) to secure the telemetric device (44) in the body cavity.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: January 27, 2004
    Assignee: The Cleveland Clinic Foundation
    Inventors: Shuvo Roy, Kenneth Ouriel, Aaron J. Fleischman
  • Publication number: 20040011365
    Abstract: In a distal targeting system a hand-held location pad is integral with a guide section for a drill or similar surgical instrument, and has a plurality of magnetic field generators. A sensor, such as a wireless sensor, having a plurality of field transponders, is disposed in an orthopedic appliance, such as an intramedullary nail. The sensor is capable of detecting and discriminating the strength and direction of the different fields generated by the field generators. Control circuitry, preferably located in the location pad is responsive to a signal of the sensor, and determines the displacement and relative directions of an axis of the guide section, and a bore in the orthopedic appliance. A screen display and optional speaker in the location pad provide an operator-perceptible indication that enables the operator to adjust the position of the guide section so as to align its position and direction with the bore.
    Type: Application
    Filed: December 6, 2002
    Publication date: January 22, 2004
    Inventors: Assaf Govari, Avinoam Dayan, Dale G. Davison, Thomas G. Ferro
  • Publication number: 20040011366
    Abstract: A system for monitoring and/or affecting parameters of a patient's body and more particularly to such a system comprised of a system control unit (SCU) and one or more other devices, preferably battery-powered, implanted in the patient's body, i.e., within the envelope defined by the patient's skin. Each such implanted device is configured to be monitored and/or controlled by the SCU via a wireless communication channel. In accordance with the invention, the SCU comprises a programmable unit capable of (1) transmitting commands to at least some of a plurality of implanted devices and (2) receiving data signal from at least some of those implanted devices. In accordance with a preferred embodiment, the system operates in closed loop fashion whereby the commands transmitted by the SCU are dependent, in part, on the content of the data signals received by the SCU.
    Type: Application
    Filed: March 17, 2003
    Publication date: January 22, 2004
    Inventors: Joseph H. Schulman, Robert Dan Dell, John C. Gord