Abstract: The breast-cancer recovery system comprises a breast cancer recovery garment, an organizational subsystem and a needs kit. The breast cancer recovery garment comprises a body portion defining an opening, positioned, configured and dimensioned to allow the performance of a breast cancer treatment procedure and a closure device suitable for closing the opening when a procedure is not being performed. The body portion of the garment defines the elongated pocket proximate the bottom edge, extending along the bottom edge and defines slits in at least one of the sleeves. The body portion of the recovery garment comprises of a warm material and/or of decorative pattern. The organizational subsystem comprises a frame configured to support a plurality of color-coded files, and marked with identification tabs which relate to breast cancer patient needs, and customized medical information.

Abstract: Methods for making an using convenience kits for hazardous drug (liquid) transfer from vials to syringes and target IV connectors. The following methods for making and using are disclosed: (1) Using a conventional plastic bag as a vial and vial adapter enclosing shroud. (2) Using of a flange (i.e. latch arm) free vial adapter which may, therefore, be used for a large variety of vial sizes. (3) Providing a seal about an access hole through which a vial adapter dispensing portion provides a closed fluid dispensing pathway. (4) Using the shrouding bag and an associated elastic band to provide desired stability of a spiked vial. (5) Accessing, measuring and transferring vial contents directly from a vial to a target IV container.

Abstract: A medical product package assembly includes a package having an interior flexible sheet disposed between two exterior flexible sheets, the interior and exterior flexible sheets coupled together to form a first compartment and a second compartment wherein the first compartment and the second compartment are adjacently disposed and are formed on opposite sides of the interior flexible sheet, and a releasable seal path extends across a length of the first and second compartments.

Abstract: The present disclosure describes a disposal bag, kit and method for performing pleural drainage that may be used by a patient at home or away from home. The kit for drainage of a body cavity has instruments and supplies needed to drain the body cavity, a disposal bag made from two superposed, water impervious sheets sealed about a substantial portion of their perimeter using a water impervious bond. The bag is usable for disposal of the instruments and supplies after drainage of the body cavity. The superposed sheets also provide a work sheet to prepare and use the instruments and supplies.

Abstract: Disclosed herein are materials and methods related to vaccines. Materials and methods for delivery of a payload, e.g., an immunogen, to the reticuloendothelial system via non-circulating lymphoid cells are provided.

Abstract: Intelligent first-aid kit (1) includes of a fixed first-aid kit of the conventional first-aid kits for storing the most important drugs which it is important to have for emergencies or chronic illnesses. A parallelepipedal is container divided into several elongated compartments (2), preferably with a rectangular cross section and a vertical orientation, which includes a drawer (3), an input reader (5.1), an output reader (5.2), a slot (4) for the insertion of an electronic health card, a keypad (6), a screen (7) and a control module (8).

Abstract: The invention relates to solid pharmaceutical or veterinary compositions comprising substantially pure Tulythromycin A in form of an addition salt with one or more acids, and to methods for preparing them. Following reconstitution with an aqueous solvent, the resulting solutions of Tulathromycin A may be administered to a mammal in order to treat bacterial or protozoal infections.

Abstract: In one aspect, the invention features a textured microthread that includes or is fashioned from a naturally occurring polymer and that has a surface comprising micron-scale ridges with intervening grooves.

Abstract: The present invention relates to aqueous solutions useful as pharmaceutical compositions of posaconazole for intravenous administration. These compositions include a solubilizing agent, such as a modified ?-cyclodextrin in an acidified solution, which can also include a chelating agent such as disodium edetate (EDTA). In clinical trials, a 200 mg posaconazole dose of the selected composition was found to achieve acceptable pharmacokinetic properties.

Abstract: A carrying case (500) and handle (504) for accommodating a portable topical negative pressure therapy apparatus (200) comprising a device (202) and a waste canister (204) separable therefrom, the waste canister having an aspiration conduit (274) emerging therefrom is described, the carrying bag comprising an apparatus receiving pouch (502), said pouch having opening and closing means (522, 524) at a lower portion thereof and said handle (504) being directly attached to said apparatus.

Abstract: The method of performing multiple oral and nasal surgical procedures in the head and neck region provides a systematic procedure for the performance of multiple operations for correcting various ear, nose, and throat conditions that cause snoring and obstructive sleep apnea (OSA) in the patient. The method allows the surgeon to perform multiple operating procedures in the nose, mouth, and/or throat in a single operating session, due to the use of hemostatic sheet and gel treatments in lieu of suturing and post-operative nasal hemostatic packs that preclude nasal breathing. The various surgical implement kits allow the surgeon to select the appropriate kit according to the procedure(s) to be performed. The procedure(s) is/are selected in accordance with a specific customized treatment plan that is developed by the surgeon for the individual patient, which other surgeons involved in snoring or OSA surgery can comprehend.

Abstract: A device for treatment of nosebleeds having an elongated body configured to be positioned between the upper gum and the portion of the face below the nose and above the top lip of a human. When so positioned intra-orally, the device exerts pressure on an area of nasal vascularization of the human. Also, a nosebleed package having a sterile inside environment and a nosebleed device packaged therein, and a box containing a plurality of nosebleed packages.

Abstract: A prophylactic kit apparatus configured to be used with only a single patient includes a plurality of sealed modules and a housing configured to contain those sealed modules such that only one of the plurality of sealed modules can be removed from the housing at a time. Each of the plurality of sealed modules contains at least one prophylactic agent to be used in service of the patient. These sealed modules are to be used in a particular order and the housing is further configured to facilitate the removal of the sealed modules in only that particular order.

Abstract: A storage system for storing used surgical towels, sponges or other medical waste materials includes a rear panel having an upper portion and a lower portion formed from a flexible sheet material. The upper portion of the rear panel has a coupling mechanism for coupling the device to a sterile structure of a surgical room. In certain embodiments, the rear panel may have a weakened partition area for separating the lower portion from the upper portion. A compartment assembly is formed by two or more flexible compartments provided on the lower portion of the rear panel. Each compartment may be liquid impervious and have an upper opening for introducing materials into the compartment. Each compartment has a forward wall that is at least partially transparent so that the contents of the compartment are observable. All components of the storage device may be sterile for use in a sterile environment. In certain embodiments, a storage system may be provided by coupling at least two storage devices together.

Abstract: A kit for use post-operatively by patients who have undergone cataract surgery and are unable to gather the medications and eyewear required for recovery, comprising a container for antibiotic and anti-inflammatory medications, special eyeglasses, an eye shield, and instructions for use of the contained products.

Abstract: A spinal implant device has a synthetic or metallic or a combination thereof of these materials in an implant body structure and stem cells in a coating, or a sheet, wrap or a membrane wrap applied to surfaces on the implant body structure or alternatively filled with a plug of stem cell laden material. The implant body structure preferably has an aperture or channel. The spinal implant device may include anchoring holes to secure the device to the spinal skeletal structure with fasteners or alternatively can simply be held in place by and between adjacent vertebrae.

Abstract: Novel compositions comprising viral fusion inhibition compounds and viral replication inhibition compounds as well as methods of their use are disclosed. The novel compositions are useful, inter alia, in the prevention, inhibition and/or treatment of Dengue Fever (DF) or Dengue Hemorrhagic Fever (DHF).

Abstract: An oximeter has a housing configured to have a cavity defining portion that is adapted to be fitted with covers of various dimensions to effect receptacles of different dimensions for accommodating differently sized sensor of sensor assemblies that are matable to the oximeter for sensing physical attributes of a patient. Each of the covers, once fully fitted to the housing, is fixedly latched thereto unless a force that overcomes the latching is applied to remove the cover. The effected receptacle is adapted to biasedly retain a corresponding sensor placed therein. The holstered sensor therefore would not accidentally fall out or be removed from the receptacle, until the user deliberately applies a force to remove the sensor from the receptacle.

Abstract: A first aid kit organized with pockets containing first aid and emergency preparedness supplies and equipment and a system for refilling. Each pocket in the kit contains supplies and equipment useful in providing initial care for a particular illness or injury and is quickly identified through textual labels and transparent elements. The pockets are connected into a strip of pockets which is folded to fit within a case. The strip of pockets is easily deployed from the case facilitating rapid and accurate identification, selection, and acquisition of items appropriate for initial care of a particular illness or injury by comprehensive visual presentation of the organizational scheme and the supplies and pieces of equipment themselves.

Abstract: A tray and packaging system for a prosthetic valve delivery system permits conversion from a storage and/or shipping configuration to a set up and preparation configuration. In a first configuration, a delivery system can be supported by first and second main trays with the elongate catheter of the delivery system arranged to extend linearly from the first main tray to the second main tray, and in a second configuration, the delivery system can be supported by the first and second main trays with the elongate catheter of the delivery system turned back in a U-shaped manner with the deployment portion of the delivery system positioned to the side of the control handle portion of the delivery system.

Abstract: Embodiments of the present invention include a surgical kit for preparation of a patch for implantation into a human body, characterized in that it comprises a package containing, on one hand, a synthetic substrate (1) and, on the other hand, means for treatment of the substrate with a solution (3) including at least one biologically active component (4, 5), adapted to integrate the biologically active component with the substrate. Embodiments of the invention include a patch for implantation into the human body, comprising a synthetic substrate (1), characterized in that at least one biologically active component (4, 5) is integrated with the substrate using the surgical kit.

Abstract: A first aid system organized with pockets containing first aid and emergency preparedness supplies and equipment and a system for refilling. Each pocket in the kit contains supplies and equipment useful in providing initial care for a particular illness or injury and is quickly identified through textual labels and transparent elements. The pockets are connected into a strip of pockets which is folded to fit within a case. The strip of pockets is easily deployed from the case facilitating rapid and accurate identification, selection, and acquisition of items appropriate for initial care of a particular illness or injury by comprehensive visual presentation of the organizational scheme and the supplies and pieces of equipment themselves.

Abstract: A plasticized elastomer includes a polymeric carrier and a volatile compound, such as a fragrance, medicament, or antimicrobial, disposed in the polymeric carrier. The polymeric carrier absorbs microwave energy and slowly dissipates it as heat until the polymeric carrier reaches thermal equilibrium with the ambient temperature. The heat of the polymeric carrier increases a vapor pressure of the volatile compound, which boosting its evaporation into the ambient environment.

Abstract: A package is provided to include first and second sheets being releasably sealed together in a manner to define multiple compartments, each having one or more medical implements. A perimeter sealed region can have a seal width greater than an intermediate sealed region. A longitudinal intermediate sealed region and a transverse intermediate sealed region can be arranged within the perimeter sealed region. Formation of the perimeter sealed region along first and second ends of the package can be subsequent to the perimeter sealed region along third and fourth ends of the package. Before the formation, compartments having an opening facing the first end can receive medical implements, and compartments having an opening facing the second end can receive medical implements. The medical implements can remain uncovered by individual pouches when inserted into the respective compartments, thereby reducing manufacturing costs and environmental wastes.

Abstract: The present invention provides and a plastic container and multilayered films, which comprises a heat-sealable seal layer, a cyclic polyolefin layer, and an outermost layer, wherein the seal layer comprises polypropylene, the cyclic polyolefin layer comprises a cyclic polyolefin polymer or a cyclic polyolefin copolymer, and the outermost layer comprises a layer containing polypropylene, and which further comprises a resin composition layer comprises a blended product of a propylene polymer and a styrene elastomer. The plastic container of the present invention can suppresses a reduction in the medicament content of a liquid-state medicament and is excellent in terms of shock resistance, handling ability during the filling of the container with the medicament, and the moldability and transparency of the container.

Abstract: An amino acid analog is provided, in syn-stereoisomeric form, anti-stereoisomeric form, or a combination thereof. The amino acid analog includes a cyclobutane ring with at least one of an amine group and a carboxyl group attached to one carbon node of the cyclobutane ring. A chain of moieties X, Y, and Z attached to one of remaining three carbon nodes of the cyclobutane ring. X is a chelating agent selected from a group comprising DCTA, DOTA, DTPA, EDTA, NOTA, PCTA, and TETA. Y is a linking moiety selected from a group comprising —NH—CO— and —NH-p-CHSN-Bn- where the linking moiety facilitates incorporation of the chelating agent into the amino acid analog. Z is a metal radioisotope selected from a group comprising Cu-60, Cu-61, Cu-62, Cu-64, Cu-67, Ga-67, Ga-68, Y-86, Y-88, Y-90, Sr-85, Sr-89, Gd-153, Gd-157, Sm-153, Lu-177, W-185, Re-186, Re-188, and Ir-192.

Abstract: This invention relates to the use of cortisol blockers (glucocorticoid receptor [GR] antagonists) for the prevention or treatment of stress induced hair loss.

Abstract: A medical organizer provides a professional, such as an anesthetist, quick access to the various items needed during a medical procedure without the need to turn away from the procedure. The organizer is formed of main housing that stabilizes various lines, such as circuit lines, IV lines, suction line etc., and also holds narcotics locked until needed. A secondary housing is removably held within the main housing and holds various implements such as catheters, swabs, alcohol, syringes and vials, waste receptacles, gauze, etc. The main housing can be secured to an IV post or operating room bed rail with the secondary housing held therein, or the secondary housing can be deployed and secured separately.

Abstract: A method of treatment and a package that is designed to accomplish this. The package provides the pet owner with a pack containing individual doses of topically applied medications pre-packaged with an oral taste treat. The topically applied medication contains at least one pharmaceutically active ingredient selected from the group of chemical families comprising phenylpyrazoles, macrocyclic lactones, neonicotinoids, synthetic pyrethroids, insect growth regulators, amidines, semicarbazones, spinosyns, octadepsipeptides, and pyrazinoisoquinolines, or any combination thereof. The treat can be administered either before the topically applied treatment is given so as to relax and distract the pet, or after the treatment is given so as to reward the pet and help it forget the stress of treatment. The treat can also be shaped to signify the type of animal to be treated.

Abstract: This invention is directed to methods for the treatment and prevention of malaria comprising administering a combination of ferroquine, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and an artemisinin derivative, and to pharmaceutical compositions comprising such combination.

Abstract: The invention relates to compounds and methods for the prevention and/or treatment of infection after stroke.

Abstract: The invention provides immunostimulatory compositions and methods of administration thereof. Also provided are methods of administering a tryptanthrin compound in an effective amount to enhance the immune response of a subject to an antigen. Also provided are methods of administering an effective amount of a tryptanthrin to stimulate the immune response in a subject for the treatment of cancer. Further provided are methods of administering a tryptanthrin compounds as an immunotherapeutic in the treatment of infectious diseases.

Abstract: This invention relates to compositions and methods for treating GC-responsive conditions and for reducing and preventing side-effects of GC treatment in patients.

Abstract: The invention relates to a method for producing an aqueous, pharmaceutical formulation comprising an insulin, an insulin analog, or an insulin derivative, wherein the ready-made formulation takes place directly by dissolving the insulin, the insulin analog, or the insulin derivative as a solid in a suitable solvent mixture.

Abstract: Compositions, kits and regimens for treatment of damaged skin, especially décolletage, include application of a retinoid, hydroquinone or hydroquinone derivatives, and a composition containing a multi-metal complex.

Abstract: The present invention is directed to compositions, devices, and methods for non-irritatively treating and preventing mucositis, such as chronic rhinosinusitis (CRS). Some aspects of the invention concern compositions comprising or consisting essentially of sodium phosphate buffer (e.g., sodium phosphate dibasic and sodium phosphate monobasic) and calcium carbonate; mucoadministration devices and kits containing such compositions; and methods for treating or preventing mucositis conditions such as CRS, comprising mucoadministering a composition of the invention to a subject in need thereof.

Abstract: The present invention provides compounds that are effective in treating central nervous system disorders and maintaining normal brain function. Methods of making and using the compounds are also provided.

Abstract: Multi-dose packages of nutritional supplements are provided that are designed for regular and continuous use by a specific target (i.e., consumer) over a reoccurring predetermined period of time. The multi-dose packaging of nutritional supplements contains supplements that vary in dosage and that are each intended to be taken at a specific time during the predetermined period of time. Each supplement in the series is tailored to contain unit dosages of nutritional supplements that are designed to address specific needs of the intended consumer during the predetermined period of time at which the supplement is intended to be ingested.

Abstract: The present invention relates to a medication tray comprising a plurality a sealed vessels comprising one or more doses of a medicament; a plurality of individually spaced compartments that are adapted to receive the individually sealed vessels; and means for releasably retaining said sealed vessels within said compartments. The tray further comprises a detection means adapted to detect and monitor when individual vessel are dispensed from the compartments of the tray.

Abstract: Multi-dose packages of nutritional supplements are provided that are designed for regular and continuous use by a specific target (i.e., consumer) over a reoccurring predetermined period of time. The multi-dose packaging of nutritional supplements contains supplements that vary in dosage and that are each intended to be taken at a specific time during the predetermined period of time. Each supplement in the series is tailored to contain unit dosages of nutritional supplements that are designed to address specific needs of the intended consumer during the predetermined period of time at which the supplement is intended to be ingested.

Abstract: The present invention relates to methods kits and combined compositions using DFO-metal complexes, specifically, Zinc-desferrioxamine (Zn-DFO), gallium-desferrioxamine (Ga-DFO) complexes and any combinations thereof for preventing, treating, ameliorating or inhibiting an immune-related disorder, specifically, a skin-related inflammatory disorder such as psoriasis, an inflammatory respiratory condition such as asthma, and an autoimmune disease such as diabetes and any immune-related disorder.

Abstract: Devices and methods are disclosed for protecting individuals from the sharp ends of medical objects following use on a patient. Such sharp objects include hypodermic needles, scalpel blades, cannulae, trocars, and the like. The invention utilizes a disposable protective cover for the used sharp. The protective cover is designed to surround and embed the sharp in a permanent cover that is blunt and will not permit further puncture or cutting with the sharp. In an embodiment, the protective cover also absorbs any fluids on or in the used sharp and prevents any fluids from escaping the protective cover. The sharp cover is configured to irreversibly lock, once closed. A refillable or replaceable dispenser dispenses the protective covers at points of use. A disposable receptacle receives the used sharp embedded in the protective cover. When the receptacle is full, the entire receptacle may be discarded in a medical waste container.

Abstract: The present disclosure relates to medical packaging for the accommodation of medical supplies. The medical packaging discussed herein has a plurality of panels, including a first panel, a second panel, and a third panel, that are releasably secured together to establish a first sterile environment between the first panel and the second panel for the retention of a first medical supply, and a second sterile environment between the second panel and the third panel for the retention of a second medical supply. The panels are configured for relative movement such that movement of the first panel relative to the second panel reveals the first medical supply without compromising the second sterile environment, and movement of the second panel relative to the third panel reveals the second medical supply. The panels are arranged for sequential separation in accordance with the steps of the procedure in which the medical supplies are employed.

Abstract: A carrying case (500) and handle (504) for accommodating a portable topical negative pressure therapy apparatus (200) comprising a device (202) and a waste canister (204) separable therefrom, the waste canister having an aspiration conduit (274) emerging therefrom is described, the carrying bag comprising an apparatus receiving pouch (502), said pouch having opening and closing means (522, 524) at a lower portion thereof and said handle (504) being directly attached to said apparatus.

Abstract: A composition which includes a carboxamide, preferably ribavirin, for treating viral diseases in humans. A preferred embodiment of the subject invention comprises a very high dose (>600 mg) of ribavirin, and more preferably between about 800-1200 mg of ribavirin or more per dosage form.

Abstract: Methods for treating multiple sclerosis (MS) with a CD20 antibody using special dosing regimens and protocols are described. Articles of manufacture for use in such methods are also described.

Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

Abstract: The present disclosure relates to an antibody or an epitope-binding fragment thereof that specifically binds to an EphA2 receptor. It further relates to a conjugate comprising a cytotoxic agent which is co-valently bound to the antibody and a method for preparing such a conjugate.

Abstract: A pill assembly configured to receive the correct selection of medications in the correct dosages for a particular patient. The pill assembly comprises containers wherein at least one of the containers is configured to receive a plurality of different pills. The containers are adjacent to one another. The pill assembly also comprises a plurality of lids. Each of the lids is configured to seal a corresponding container. The containers have a top surface with a flange that is configured to receive the corresponding lid. Each lid has a surface that is configured to receive a printable indicia with patient specific information. The pill assembly may also comprise a sleeve that is configured to slidably interface with the containers.

Abstract: A system and method for storing medical information and medications for use in an emergency. The system includes a rigid storage container with personalized individual patient medical information on an external surface of the storage container, including a photograph of the individual patient, information regarding the contents of the storage container and emergency contact information. The method uses an internet-based computer system to generate a summary of patient medical information which is mounted for viewing on an external surface of the storage container. The summary is supplied and mounted for viewing from an external surface of the storage container. Once the medications are included within the storage container, a care giver is provided with the storage container for safe keeping in the event of a health emergency.