Abstract: A device for measuring surface temperature of a turbine blade based on a rotatable prism includes a probe, a prism rotating apparatus and an optical focusing apparatus. The prism rotating apparatus and the optical focusing apparatus are located inside the probe. The probe includes a probe outer casing, a probe inner casing, a water-cooled casing pipe, a sapphire window piece, a quartz prism, a light pipe, a collimating lens, a focusing lens and an infrared array detector. The prism rotating apparatus includes a rotary motor, a worm, a gear and a prism rotary table, the rotary motor rotates to drive the prism rotary table to rotate. The optical focusing apparatus includes a telescopic motor, a coupler, a lead screw and a drive rod, the telescopic motor rotates to drive the lead screw, so as to further drive the drive rod to move along the slot.

Abstract: A sample cell includes an annular support surrounding a sample region. A set of reflectors of the annular support define an optical path that reflects a source beam in a sequence of alternating directions through the sample region at a plurality of different angles such that the source beam exits the set of reflectors after having passed through the sample region a plurality of times. A micro-cell is positionable in the sample region including multi-dimensionally distributed nano-pores. A slidingly adjustable lens forms part of source and detector photomixing packages.

Abstract: A device and method for evaluating long-term operation of a transformer oil pump. An inlet of an oil pump is connected to an outlet of an oil tank through an oil pipe, and an outlet of the oil pump is connected to an inlet of the oil tank through an oil pipe. A pressure gauge is provided on the oil pipe to the inlet and the outlet of the oil pump, respectively. An ultra-high-frequency (UHF) sensor is provided on an inner wall of an oil pipe close to the oil pump. A pressure difference between the oil pipes to the inlet and to the outlet of the oil pump is monitored. A three-phase unbalanced current of a stator winding is monitored. The vibration of the oil pump is monitored. The rotor-to-stator rub is monitored. Based on the above inspection, a long-term health status of the oil pump is determined.

Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.

Abstract: An air filter includes filter media, a sensor, and circuitry coupled to the sensor, the circuitry configured to receive data from the sensor representative of the condition of the filter media and wirelessly transmit such data. The data may be received by a device with a display to use the information to present an indication of the filter media condition to a user.

Abstract: A method of detecting the presence of insects, including larvae, in an indoor environment, which includes the steps of (a) obtaining a sample of volatile organic compounds (VOCs); (b) separating the sampled VOCs; (c) detecting the presence or absence of “target” VOCs from at least one category: “category 1 VOCs”—VOCs emitted independently of the support on which the insects develop and emitted only in an insect infestation VOCs, “category 2 VOCs”—VOCs emitted independently of the support but may have biological origins other than insects, and “category 3 VOCs”—VOCs emitted depending on the support and emitted only in an insect infestation; (d) calculating both an insect infestation index (“3I”) and a limit value (“VL”) based on the presence or absence of the target VOCs; and (e) comparing the “3I” and “VL” values. The environment is infested for a “3I” value strictly greater than the “VL” value.

Abstract: A breath analyte capture device includes a breath input port into which a user exhales a breath sample, and a cartridge insertion port for receiving a disposable cartridge containing an interactant. During exhalation of a breath sample, at least a portion of the breath sample is routed through the cartridge such that the analyte (such as breath acetone) is captured by the interactant. In some embodiments, the concentration of the analyte in the breath sample is measured by monitoring a chemical reaction that occurs in the disposable cartridge. The chemical reaction may be monitored by illuminating the cartridge at each of multiple light wavelengths while measuring reflected light.

Abstract: A flow cell assembly (16) for a fluid analyzer (14) that analyzes a sample (12) includes (i) a base (350) that includes a base window (350B); (ii) a cap (352) having a cap window (352B) that is spaced apart from the base window (350B); and (iii) a gasket (360) that is secured to and positioned between the base (350) and the cap (352), the gasket (360) having a gasket body (360A) that includes a gasket opening (360B). The gasket body (360A), the base (350) and the cap (352) cooperate to define a flow cell chamber (362). Moreover, an inlet passageway (366) extends into the flow cell chamber (362) to direct the sample (12) into the flow cell chamber (362); and an outlet passageway (368) extends into the flow cell chamber (362) to allow the sample (12) to exit the flow cell chamber (362).

Abstract: A device that is configured to detect spectrally resolved emission from a material is disclosed. The device includes an optical cavity comprising a pair of substrates separated by a distance defined to restrict a photonic density of states (DOS) of the material to be detected, a detector oriented with respect to the optical cavity to receive emission from the optical cavity and a controller configured to control the distance. The pair of substrates includes facing reflective surfaces.

Abstract: A detection assembly and a method for producing a detection assemblies are disclosed. In an embodiment a detection arrangement includes an emitter configured to generate radiation having a peak wavelength in an infrared spectral range, a detector configured to receive the radiation, a mounting surface comprising at least a first contact surface and a second contact surface for external electrical connection of the detection arrangement, a form body adjoining the emitter and the detector at least in places and deflection optics, on which the radiation impinges during operation of the detection arrangement so that an optical path is formed between the emitter and the detector by the deflection optics, wherein the deflection optics include a scattering body into which the radiation enters during the operation through a surface of the scattering body facing the emitter.

Abstract: Various embodiments may relate a chemical sensor. The chemical sensor may include a substrate including a first sealed (or isolated) cavity and a second sealed (or isolated) cavity separate from the first sealed (or isolated) cavity. The chemical sensor may also include an emitter in the first sealed (or isolated) cavity, the emitter configured to emit infrared light. The chemical sensor may further include a detector in the second sealed (or isolated) cavity. The chemical sensor may also include a waveguide configured to carry the infrared light from the emitter to the detector. The waveguide may include a sensing portion configured such that a property of the infrared light carried through the sensing portion changes in response to a chemical entity in contact with the sensing portion. The detector may be configured to detect the change in the property (of the infrared light).

Abstract: Methods, apparatuses, and systems for improving gas detecting devices are provided. An example gas detecting device may include a receiver element. In some examples, the receiver element may include a sample filter component and a reference filter component. In some examples, the sample filter component may be positioned coaxially with the reference filter component.

Abstract: Apparatuses for measuring sample materials (such as tissue samples) and associated methodologies and instrumentation involve a spectroscopy system or device configured with a sample measuring device (e.g., an attenuated total reflection infrared (ATR-IR) sample measuring device) including a crystal defining a sample receiving surface/interface operatively connected to an IR source and an IR detector. The sample receiving surface/interface facilitates assessing presence (and optionally, amount) of a fixative (e.g., formaldehyde) in sample materials, tissue samples for example. Measurements are taken at one or multiple locations within a sample placement structure/area, which can be provided in the form of a probe or a raised piercing structure containing one or more ATR-IR (or other) sample measuring devices.

Abstract: An apparatus includes a substrate, a first patterned layer, and a second patterned layer. The first patterned layer may be coupled to the substrate and may have a first metasurface pattern. The second patterned layer disposed separately from the substrate and the first patterned layer, and may have a second metasurface pattern. Movement of the first patterned layer relative to the second patterned layer may be controllable via control circuitry such that a gap distance of a gap between the first patterned layer and the second patterned layer is changed to cause a transmittance for radiant energy of a selected wavelength passing through the apparatus to change from a first transmittance value to a second transmittance value.

Abstract: For the purpose of gas quality monitoring, a spectroscopic examination of a gas sample from a space (10) to be monitored is carried out, e.g. by Raman spectroscopy. The spectroscopic examination yields a measurement spectrum extending over a wavelength range. A deviation of the measurement spectrum from at least one comparison sample (160) is then detected. Depending on the detected deviation, a gas quality warning (QW) is produced.

Abstract: A method for measuring the concentration of a gas includes heating a first gas with a pulse of light, the pulse of light having a wavelength absorbed by the first gas, wherein the first gas exerts pressure on a flexible membrane. The method includes receiving a first signal indicating a first deflection of the membrane, wherein the first deflection is due to a change in pressure of the first gas and receiving a second signal indicating a second deflection of the membrane occurring after the first signal, wherein the second deflection is due to the change in pressure of the first gas. The method includes determining a difference between the first signal and the second signal and, based on the difference between the first signal and the second signal, determining a first concentration of the first gas.

Abstract: A breath test system is provided comprising a sensor unit configured to sense the presence or concentration of a volatile substance present in air flowing through a predefined inlet area, and generate a signal corresponding to the concentration of said substance. Also provided is an apparatus configured to detect the presence of a person in the vicinity of said input area, and registering said presence, and configured to respond by delivering an output. This apparatus includes a unit configured to call for immediate attention of said person, and upon registration of the presence of said person, provide instructions to said person to direct an expiratory air flow towards said inlet area. An analyzer to determine breath substance concentration of said person is also provided, the determination based on said signal corresponding to the substance concentration.

Abstract: A method of training a neural network (Convolutional Neural Network-CNN) including reduced graphical annotation input is provided. The training method can be used to train a Testing CNN that can be used for determining Hemolysis (H), Icterus (I), and/or Lipemia (L), or Normal (N) of a serum or plasma portion of a test specimen. The training method includes capturing training images of multiple specimen containers including training specimens, generating region proposals of the serum or plasma portions of the training specimens; and selecting the best matches for the location, size and shape of the region proposals for the multiple training specimens. The obtained features (network and weights) from the training CNN can be used in a testing CNN. Quality check modules and testing apparatus adapted to carry out the training method, and characterization methods using abounding box regressor are described, as are other aspects.

Abstract: A device (1) for detecting microleakages from kegs (2) and similar containers containing a liquid with CO2 under pressure is provided with an outlet mouth (21) and a sealing valve (22). The device (1) includes a detection head (10) adapted to seal and couple with the keg (2) at the outlet mouth (21). The detection head (10) includes a measuring chamber (11) adapted to face over the outlet mouth (21). A light source (12) has an infrared component with wavelengths corresponding to CO2 absorption wavelengths facing the measuring chamber (11). A light sensor (13) faces the measuring chamber (11) for detecting the infrared light component with wavelengths corresponding to the CO2 absorption wavelengths emitted in the measuring chamber (11) by the light source (12). The measuring chamber (11) includes at least one air inlet (14) and at least one air vent (15).

Abstract: An embodiment of the present disclosure is a sample vessel for a holding a sample for analysis by a sample analyzer. The sample vessel includes a body that includes a bottom, an open top spaced from the bottom along a first axis, a side wall that extends from the open top to the bottom, and an interior chamber for holding a sample and that extends from the open top toward the bottom along the first axis. The body includes an opaque portion, a first translucent portion, and a second translucent portion spaced from the first translucent portion a distance that extends along a second axis that is perpendicular to the first axis. The first and second translucent portions are each disposed along the bottom of the body.

Abstract: A method of optimizing the layout of a smoke detection system in a space includes obtaining requirements for the smoke detection system, accessing a digital representation of physical and functional characteristics of the space, integrating the requirements and the digital representation of physical and functional characteristics of the space in a fiber deployment algorithm, determining a layout of smoke detection system components based on the fiber deployment algorithm, and installing the smoke detection system in the space according to the determined layout.

Abstract: Devices, systems, and methods herein relate to predicting infection of a patient. These systems and methods may comprise illuminating a patient fluid in a fluid conduit from a plurality of illumination directions, measuring an optical characteristic of the illuminated patient fluid using one or more sensors, and predicting an infection state of the patient based at least in part on the measured optical characteristic.

Abstract: The invention relates to a device for measuring, in near-real-time, the level of black carbon, brown carbon, organic carbon, total carbon and CO2 in air. The device also provides for a direct calculation of aerosol angstrom coefficient as well as estimation of emissions rates of black carbon or brown carbon from nearby combustion sources.

Abstract: In a general aspect, a vapor cell includes a body defined by a stack of layers bonded to each other. The stack of layers defines an array of cavities that includes first and second subsets of cavities. The first subset of cavities extends through intermediate layers of the stack of layers and the second subset of cavities extends entirely through the stack of layers. The vapor cell includes a vapor or a source of the vapor disposed in each of the first subset of cavities. The stack of layers includes a first end layer disposed at a first end of the body and a second end layer disposed at a second, opposite end of the body. The intermediate layers are positioned between the first and second end layers.

Abstract: A device for detecting characteristics of a fluid, with a light source for emitting several light beams, of which one of the light beams is a measurement beam, which is provided for a passage through the fluid, and another light beam is a reference beam, which is provided for bypassing the fluid, with a movable cover device arranged downstream of the light source, which cover device is provided for covering the light beams and which is arranged so as to be transferable between a first position releasing the measurement beam and covering reference beam, and a second position covering the measurement beam and releasing the reference beam, and with a light detector arranged downstream of the cover device.

Abstract: In accordance with an embodiment, a gas sensor includes a substrate having a cavity for providing an optical interaction path; a thermal emitter configured to emit broadband IR radiation; a wavelength selective structure configured to filter the broadband IR radiation emitted by the thermal emitter; and an IR detector configured to provide a detector output signal based on a strength of the filtered IR radiation having traversed the optical interaction path.

Abstract: Provided herein are an optical test platform and corresponding method of manufacturing the same. The test platform may include a shell defining a cavity for receiving a sample tube, a first aperture, and a second aperture. The first aperture and the second aperture of the shell may each be configured to optically couple the cavity with an exterior of the shell. The test platform may further include a first window and a second window embedded in the shell. The first window may seal a first aperture and the second window may seal a second aperture. The first window and second window may each permit the optical coupling of the cavity with the exterior of the shell. The first window and the second window may be optically coupled via the cavity, and the shell may prohibit optical coupling between the first window and the second window through the shell.

Abstract: A terahertz wave signal analysis device includes a fitting processing unit 13 that fits synthetic waveforms of a plurality of normal distribution functions which differ in at least one of a center frequency, an amplitude, and a width to a frequency spectrum obtained from a terahertz wave signal and a graph generating unit 14 that generates a graph using at least one of a center frequency, an amplitude, and a width of a plurality of normal distribution functions used in the fitting as parameters, and it is possible to visualize a feature corresponding to a characteristic of a sample in the form of a graph in an easy-to-understand manner by approximating a frequency spectrum which does not clearly appear because a difference in the characteristic of the sample becomes a feature of a waveform by synthetic waveforms of a plurality of normal distribution functions in a form in which the characteristic of the sample is taken over and generating a graph on the basis of parameters of a plurality of normal distributio

Abstract: A flow cell includes a cell into which a liquid to be measured is introduced and is arranged so that a measurement light to be used for measuring an optical characteristic of the liquid enters one side of the cell and exits from the other side of the cell, an inlet for leading the liquid to flow into the cell, and an outlet for leading the liquid in the cell to flow out from the cell. The inlet and the outlet are provided to form an interface between a liquid flowing into the cell through the inlet and a liquid with which the cell has been already filled at two places on an optical path of the measurement light passing through the cell.

Abstract: A method for testing an analysis apparatus that analyzes a first fluid flowing through a pipe using light that has passed through a probe attached to and disposed inside the pipe such that a portion of a light path passes outside a housing of the probe. The method includes: after a second fluid that absorbs less of the light than the first fluid has been introduced into the pipe, introducing a third fluid having predetermined absorption characteristics into the housing of the probe; and analyzing the absorption characteristics of the third fluid using the light that has passed through the probe.

Abstract: Provided are a filter array, a spectral detector including the filter array, and a spectrometer employing the spectral detector. The filter array may have a multi-array structure including a plurality of filter arrays. The filter array may include a first filter array having a first structure in which a plurality of first filters with different transmittance spectrums are arranged, and a second filter array having a second structure in which a plurality of second filters with different transmittance spectrums are arranged, the second filter array being arranged to at least partially overlap the first filter array at a first position relative to the first filter array so that the multi-arrangement type filter array has a first set of absorbance characteristics.

Abstract: Gas sensor capable for in-situ non-contact optical measurements of hydrogen gas (H2) and method for measuring hydrogen gas under ambient and elevated pressures without the need for cells with extremely long optical path length. The gas sensor can be configured for dual gas measurements such as H2 and CO2.

Abstract: Embodiments relate generally to electromagnetic radiation detector devices, systems, and methods using a planar Golay cell. A method for gas detection may comprise providing a gas sealed in a cavity of a gas detector; directing radiative power from a light source through one or more target gases and through a cell body of the gas detector toward the cavity and a wavelength selective absorber of the gas detector, wherein the one or more target gases are located between the light source and the cavity; setting wavelength sensitivity with the wavelength selective absorber, wherein the wavelength sensitivity is irrespective of an angle of incidence (?); absorbing the radiative power by the wavelength selective absorber and by the one or more target gases; detecting, by a pressure sensing element, a pressure change caused by the absorbing of the radiative power; and determining the one or more target gases based on the detected pressure change.

Abstract: A chromatography analyzer system (10) for analyzing a sample (12) includes a MIR analyzer (34) for spectrally analyzing a sample fraction (12A) while the sample fraction (12A) is flowing in the MIR analyzer (34). The MIR analyzer (34) includes (i) a MIR flow cell (35C) that receives the flowing sample fraction (12A), (ii) a MIR laser source (35A) that directs a MIR beam (35B) in a MIR wavelength range at the sample fraction (12A) in the MIR flow cell (35C), and (iii) a MIR detector (35D) that receives light from the sample fraction (12A) in the MIR flow cell (35C) and generates MIR data of the sample fraction (12A) for a portion of the MIR wavelength range.

Abstract: The present invention concerns methods and tools for analysing biomarkers useful for diagnosing an individual, in particular a newborn, with a respiratory disease, especially a newborn suffering from respiratory distress syndrome (RDS). The method and tools of the invention can in one embodiment be used for very rapidly detecting the ratio between lecithin and sphingomyelin in very small body fluid samples, e.g. gastric aspirate of a newborn. The invention is thus useful for obtaining a rapid treatment of RDS by administration of surfactant.

Abstract: Methods and systems for analyzing a sample and generating a predictive model using cavity ring-down spectroscopy are disclosed. At least part of a sample is loaded in a ring-down cavity. For each of a set of wavelengths, a laser beam is generated and directed into the ring-down cavity. The laser beam entering the ring-down cavity is extinguished. Light intensity decay data for light exiting the ring-down cavity is registered via a light intensity sensor system. A probability is determined from the light intensity decay data for the set of wavelengths that a subject from which the sample was received has a physiological condition or a degree of the physiological condition at least indirectly using a dataset of light intensity decay data for previously analyzed samples for which the presence or the absence of the physiological condition or the degree of the physiological condition have been identified.

Abstract: A microscopic observation system with a temperature-pressure-controllable sample cell and methods. The system can be configured to perform common optical microscopic observation and polarizing microscopic observation. The system is composed of a visual autoclave, a temperature control component, a rapid cooling component, a pressure control component and an optical imaging system, and can be configured to observe an evolution process of microstructures of polymer materials in specific atmosphere and rapid temperature and pressure changing environments in a scale of 1 ?m-1 cm. A novel characterization means for researching a condensed state evolution law of polymers in high-pressure environments, and also a new thought for deep reveal of the polymer crystallization mechanism and regulation of crystallization and phase separation behaviors of the polymer materials.

Abstract: measurement device and a measurement method for measuring a temperature and an emissivity of a measured surface are provided. The measurement device includes a reflection converter, an optical receiver and a data processor. The reflection converter includes a reflector having a through hole and an absorber tube shifted between a first measurement position and a second measurement position relative to the reflector. In the first measurement position, the light incident end of the absorber tube approaches or contacts the measured surface, such that the optical receiver forms a first electrical signal. In the second measurement position, the light incident end of the absorber tube is located at or outside the through hole, such that the optical receiver forms a second electrical signal. The data processor is configured to determine a temperature and an emissivity of the measured surface according to the first electrical signal and the second electrical signal.

Abstract: A gas sensor with a gas permeable region is disclosed. In an embodiment a gas sensor includes a dielectric membrane formed on a semiconductor substrate having a cavity portion, a heater located within or over the dielectric membrane, a material for sensing a gas, wherein the material is located on one side of the dielectric membrane, a support structure located near the material, a gas permeable membrane coupled to the support structure so as to protect the material, wherein the semiconductor substrate forms the support structure.

Abstract: A gas sensor comprises a chamber configured to receive a gas; a light source configured to emit a light wave propagating through the chamber in an emission cone; a measurement photodetector and a reference photodetector, each configured to detect a light wave emitted by the light source and having passed through the chamber. The chamber extends between two transverse walls, arranged opposite one another and connected to one another by a peripheral wall extending therebetween, about a longitudinal axis (Z), and comprising a first reflective segment configured to receive a first portion of the emission cone to reflect it toward the measurement photodetector, thus forming a measurement cone converging toward the measurement photodetector. A second reflective segment of the peripheral wall is configured to receive a second portion of the emission cone to reflect it toward the reference photodetector, thus forming a reference cone converging toward the reference photodetector.

Abstract: An apparatus for heating an insulation fluid in a medium-voltage or high-voltage switchgear comprises an infrared source which is adapted to emit infrared radiation of at least one wavelength. Thus, at least one vibrational or rotational mode of at least one component of the insulation fluid is excited by absorption of at least a part of the infrared radiation, and condensation of the insulation fluid is efficiently prevented by this direct heating of the insulation fluid. A closed loop temperature regulator is used to heat only when required. A circulator in a heating chamber further provides for a mixing of the insulation fluid, thus preventing steep temperature gradients.

Abstract: The present invention relates to an electronic system comprising an electronic system comprising an electromechanical microsystem and a hermetic box encapsulating said microsystem. The box includes a fastening plane. The electromechanical microsystem includes a sensitive part and at least two beams connecting the sensitive part to the fastening plane. The beams are thermally coupled to the sensitive part and are electrically coupled to one another. The system further includes a thermal regulator of the electromechanical microsystem including an electrical circuit including at least two ends connected to the beams, and a circuit controller able to generate an electrical current in the electrical circuit to modify the temperature of the sensitive part.

Abstract: A method of detecting at least a partial blockage in a porous member separating a first volume from a second volume or inner chamber of a device includes emitting pressure waves within the inner chamber by changing a volume of the inner chamber, measuring a response via a pressure sensor responsive to pressure waves positioned within the inner chamber, and determining if at least a partial blockage is present in the porous member based upon the response of the pressure sensor.

Abstract: The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.

Abstract: A process and sensor system useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix wherein the sample volume is configured so that a sampling error caused by changes of the targeted molecule passing in and out of the sample volume is approximately the same or less than a measurement error caused by an accuracy limit of electronic components and optical elements used in the sensor system.

Abstract: A fluid flow sensing and bubble detecting apparatus includes a housing comprising a channel configured to receive a tube through which fluid flows; a sensor apparatus disposed within the housing, which includes a first sensor operable to measure flow rate of fluid and to detect bubbles in flowing fluid; and a temperature sensor operable to detect temperature of the flowing fluid; and a processor connected to receive fluid flow rate data obtained by the first sensor, to receive bubble detection data obtained by the first sensor, and to receive fluid temperature data obtained by the temperature sensor, wherein when a tube through which fluid flows is disposed in the channel of the housing, the first sensor measures the flow rate of the flowing fluid and detects bubbles therein, and the temperature sensor measures the temperature of the flowing fluid, and the processor calculates in a short period of time a fluid flow rate corrected for temperature.

Abstract: Systems and methods for delivering therapy and/or medicament to a subject use one or more sensors to generate signals that represent characteristics of ultrasonic energy emitted during the use of respiratory medicament delivery devices. Parameters based on these signals indicate energy amplitude in one or more frequency ranges. Such parameters can be used to characterize the emitted ultrasonic energy and control and/or monitor device operation and/or patient adherence.

Abstract: A deformometer includes: a cavity body; entry and exit optical cavity optics, such that the optical cavity produces filtered combined light from combined light; a first laser that provides first light; a second laser that provides second light; an optical combiner that: receives the first light; receives the second light; combines the first light and the second light; produces combined light from the first light and the second light; and communicates the combined light to the entry optical cavity optic; a beam splitter that: receives the filtered combined light; splits the filtered combined light; a first light detector in optical communication with the beam splitter and that: receives the first filtered light from the beam splitter; and produces a first cavity signal from the first filtered light; and a second light detector that: receives the second filtered light; and produces a second cavity signal from the second filtered light.

Abstract: A deformometer includes: a cavity body; entry and exit optical cavity optics, such that the optical cavity produces filtered combined light from combined light; a first laser that provides first light; a second laser that provides second light; an optical combiner that: receives the first light; receives the second light; combines the first light and the second light; produces combined light from the first light and the second light; and communicates the combined light to the entry optical cavity optic; a beam splitter that: receives the filtered combined light; splits the filtered combined light; a first light detector in optical communication with the beam splitter and that: receives the first filtered light from the beam splitter; and produces a first cavity signal from the first filtered light; and a second light detector that: receives the second filtered light; and produces a second cavity signal from the second filtered light.

Abstract: Presented herein is a method for in-situ real-time non-invasive estimation of the level of living cells proliferation and/or growth in a biological material present in a container sealed to prevent biological contamination. The method comprises measuring the concentration of at least one metabolic gas that is emitted by the living cells. The method can be adapted inter alia to detect a microorganism contamination in a storage container for platelets sealed to biological contamination, to monitor a fermentation process in a fermenter enclosing microorganisms and sealed to biological contamination, and to monitor the concentration of living cells in a bioreactor sealed to biological contamination.