Encapsulating Normally Liquid Material Patents (Class 264/4)
  • Patent number: 10279523
    Abstract: A microbubble creating method using a forming machine for creating microbubbles by: installed a microbubble generating member in a mold, feed screw or barrel for enabling a perforated tip of the microbubble generating member to be surrounded by the applied fluid polymer so that when a high pressure high temperature gas is delivered through the perforated tip of the microbubble generating member, microbubbles are created with well mixed with the fluid polymer, and the expected foamed polymer product is thus obtained after cooling.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: May 7, 2019
    Assignee: EVERFOCUS INTERNATIONAL CO., LTD.
    Inventors: Wei-Chih Liao, Cristina Chang
  • Patent number: 10238141
    Abstract: A capsule forming apparatus comprising a plurality of outputs configured to output capsule materials, a tank for housing a first capsule material and being configured to supply the first capsule material to the outputs and at least one conduit being configured to convey a second capsule material to the outputs. A method for forming capsules is also described.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: March 26, 2019
    Assignee: BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED
    Inventor: Robert Seon Whiffen
  • Patent number: 10239243
    Abstract: A microbubble creating method using a forming machine for creating microbubbles by: installed a microbubble generating member in a mold, feed screw or barrel for enabling a perforated tip of the microbubble generating member to be surrounded by the applied fluid polymer so that when a high pressure high temperature gas is delivered through the perforated tip of the microbubble generating member, microbubbles are created with well mixed with the fluid polymer, and the expected foamed polymer product is thus obtained after cooling.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: March 26, 2019
    Assignee: Everfocus International Co., Ltd.
    Inventors: Wei-Chih Liao, Cristina Chang
  • Patent number: 10239244
    Abstract: A microbubble creating method using a forming machine for creating microbubbles by: installed a microbubble generating member in a mold, feed screw or barrel for enabling a perforated tip of the microbubble generating member to be surrounded by the applied fluid polymer so that when a high pressure high temperature gas is delivered through the perforated tip of the microbubble generating member, microbubbles are created with well mixed with the fluid polymer, and the expected foamed polymer product is thus obtained after cooling.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: March 26, 2019
    Assignee: Everfocus International Co., Ltd.
    Inventors: Wei-Chih Liao, Cristina Chang
  • Patent number: 10194995
    Abstract: Systems and methods for registering and tracking multiple anatomical structures, e.g., multiple vertebrae, as a single functional unit for surgical procedures are disclosed herein. In some embodiments, the system can include a bone bridge for attaching a navigation marker to multiple vertebrae and for limiting or preventing movement between the multiple vertebrae. Various ways of attaching the bone bridge are disclosed, including fasteners that extend through gaps or throughholes formed in the bridge, bridges having a jaw portion that clamps the underlying bone, and bridges formed of adhesive or cement and directly attached to the bone. Various adjustment features are also disclosed, including joints that allow the position and/or orientation of the bridge to be adjusted in one or more degrees of freedom, and bridges that include telescoping portions or other features for adjusting a length of the bridge.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: February 5, 2019
    Assignee: Medos International Sarl
    Inventors: Masashi Neo, J. Riley Hawkins, Aniruddha Raina
  • Patent number: 10172791
    Abstract: Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 8, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Minglin Ma, Daniel G. Anderson, Robert S. Langer, Omid Veiseh, Joshua Charles Doloff, Delai Chen, Christian J. Kastrup, Arturo Jose Vegas
  • Patent number: 10066105
    Abstract: A renewable material for releasing a self-healing agent includes a renewable polymeric substrate with capsules and a reactant dispersed in the renewable polymeric substrate. The capsules may be formed from a first renewable shell polymer and may enclose the renewable self-healing agent. The reactant may be suitable for reacting with the renewable self-healing agent to form a polymer.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: September 4, 2018
    Assignee: International Business Machines Corporation
    Inventors: Dylan J. Boday, Jason T. Wertz
  • Patent number: 9974745
    Abstract: Disclosed are novel methods for making cochleates and cochleate compositions that include introducing a cargo moiety to a liposome in the presence of a solvent. Also disclosed are cochleates and cochleate compositions that include an aggregation inhibitor, and optionally, a cargo moiety. Additionally, anhydrous cochleates that include a protonized cargo moiety, a divalent metal cation and a negatively charge lipid are disclosed. Methods of using the cochleate compositions of the invention, including methods of administration, are also disclosed.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: May 22, 2018
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Raphael J. Mannino, Susan Gould-Fogerite, Sara L. Krause-Elsmore, David Delmarre, Ruying Lu
  • Patent number: 9962335
    Abstract: An object is to provide a method of manufacturing a soft capsule that is enteric and excellent in formulation properties. An enteric soft capsule is manufactured by the following steps (a) and (b): (a) preparing an enteric capsule shell liquid comprising gelatin and low methoxyl pectin having a degree of amidation of 5 to 25%, and (b) encapsulating capsule fills using the enteric capsule shell liquid prepared in the step (a) by stamping. Preferably, the jelly strength of the gelatin is 160 to 300 Bloom, the degree of esterification of the low methoxy pectin is 20 to 40%, and the enteric capsule shell liquid comprises 30 to 35 parts by mass of the low methoxy pectin per 100 parts by mass of the gelatin.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: May 8, 2018
    Assignee: FUJI CAPSULE CO., LTD.
    Inventors: Kazuhiko Watanabe, Hiroaki Hasegawa, Nahonori Inaba, Yoshiyuki Shimokawa, Kenji Kato
  • Patent number: 9852918
    Abstract: An electronic device comprising a carrier having a mounting surface, at least one electronic chip mounted on the mounting surface, an encapsulant at least partially encapsulating the carrier and the at least one electronic chip, and a plurality of capsules in the encapsulant, wherein the capsules comprise a core comprising an additive and comprise a shell, in particular a crackable shell, enclosing the core.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: December 26, 2017
    Assignee: Infineon Technologies AG
    Inventors: Peh Hean Teh, Jagen Krishnan, Swee Kah Lee, Poh Cheng Lim, Joachim Mahler, Chew Theng Tai, Yik Yee Tan, Soon Lock Goh
  • Patent number: 9820947
    Abstract: An object is to provide a method of manufacturing a seamless soft capsule that is enteric and excellent in formulation properties. An enteric seamless soft capsule is manufactured by the following steps (a) and (b): (a) preparing an enteric capsule shell liquid comprising gelatin and low methoxy pectin having a degree of esterification of 0 to 40% and a degree of amidation of 0 to 25%, the enteric capsule shell liquid having a viscosity at 50° C. of 60 to 127 mPa·s; and (b) encapsulating capsule fills with the enteric capsule shell liquid prepared in the step (a) by dripping. Preferably, the jelly strength of the gelatin is 180 to 330 Bloom, an aqueous solution of the low methoxy pectin at a concentration of 2 mass % has a viscosity at 35° C. of 8 to 15 mPa·s, and the enteric capsule shell liquid comprises 10 to 20 parts by mass of the low methoxy pectin per 100 parts by mass of gelatin.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: November 21, 2017
    Assignee: FUJI CAPSULE CO., LTD.
    Inventors: Koji Masuda, Naoki Nishimura, Akihiko Hayano, Yoshiyuki Shimokawa, Kenji Kato
  • Patent number: 9820944
    Abstract: Methods of making and resultant acidulent/carbohydrate agglomerates. The acidulent may be citric acid having particle sizes ranging from about 1 micron to 20 microns agglomerated with a soluble carbohydrate co-agglomerate to formulate the various acidulent/carbohydrate agglomerates. In certain embodiments, the carbohydrate co-agglomerate may be maltodextrin to formulate citric acid/maltodextrin agglomerates. These citric acid/maltodextrin agglomerates are shelf stable when dry, have improved flowability, compressibility, mixability; dissolve easily and quickly in water; and provide an easy ready-to-use formulation that is suitable for use in compounding various food and pharmaceutical products.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: November 21, 2017
    Assignee: THE MBP COMPANY LLC
    Inventors: Matthew M. Pearson, William Valentine, William K. Valentine
  • Patent number: 9725684
    Abstract: A seamless capsule comprises at least one core and a shell layer. The capsule can further comprise an intermediate layer which surrounds the core(s) and is surrounded by the shell layer. The shell layer comprises a material selected from the group consisting of water-soluble polymers, water-dispersible polymer, hydrogels. The shell layer can further comprise a disintegration aid.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: August 8, 2017
    Assignee: Milliken & Company
    Inventors: Gregory E. Fernandes, Robert M. MacMeccan
  • Patent number: 9711821
    Abstract: The present invention provides a lithium secondary battery and the preparation thereof, more specifically a lithium secondary battery comprising an electrode assembly having a cathode, an anode, and a separator interposed between the cathode and the anode; and a non-aqueous electrolyte solution impregnated in the electrode assembly, wherein the separator further comprises a layer having a plurality of destroyed capsules dispersed therein, the layer being formed on at least one surface of the separator coming into contact with the cathode and the anode, and the destroyed capsules has a film formed from a binder polymer and inorganic particles dispersed therebetween. The lithium secondary battery of the present invention can be prepared without the separate introducing process of a non-aqueous electrolyte solution, and has a separator exhibiting improved mechanical property and safety.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: July 18, 2017
    Assignee: LG Chem, Ltd.
    Inventors: Chul-Haeng Lee, Doo Kyung Yang
  • Patent number: 9630848
    Abstract: The method of the present disclosure is directed towards the formation of a three-dimensional carbon structure and includes the steps of adding a radical initiator to an amount of carbon starting material, forming a mixture, placing the mixture in a mold, maintaining the mixture and the mold at an elevated temperature for a period of time to form a thermally cross-linked molded mixture and removing the thermally cross-linked molded mixture from the mold. The disclosure also includes a three-dimensional carbon structure, with that structure including a thermally cross-linked carbon base material in a predetermined formation.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: April 25, 2017
    Assignee: The Research Foundation for The State of New York
    Inventors: Balaji Sitharaman, Gaurav Lalwani
  • Patent number: 9616020
    Abstract: The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: April 11, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Jaehyun Moon
  • Patent number: 9511336
    Abstract: The present invention relates to a method for producing beads comprising a material capable of gelation, said method comprising the steps of: (i) combining (a) a liquid composition comprising a material capable of gelation; and (b) a first hydrophobic phase; (ii) subjecting the liquid composition and the first hydrophobic phase, to means for emulsification in a first reactor by addition of external mechanical energy creating an emulsion comprising individual droplets comprising the material capable of gelation in the first hydrophobic phase (wherein the material capable of gelation provides a discontinuous phase and the first hydrophobic phase provides a continuous phase); (iii) stabilizing the droplets by transferring the emulsion from the first reactor to a stabilization reactor wherein the emulsion obtained in step (ii) is subjected to means for gelation in order to obtain gelation within 5 minutes or less, and the beads are formed.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: December 6, 2016
    Assignee: DPx Holdings B.V.
    Inventors: Allan Otto Fog Lihme, Marie Bendix Hansen, Rene Oehlenschlaeger Holte, Brian A. Larsen
  • Patent number: 9510609
    Abstract: The present invention is related to a seamless capsule which easily dissolves in the oral cavity etc. The present invention provides a seamless capsule comprising a capsule content solution, and a capsule shell enclosing the capsule content solution, wherein the capsule shell comprises a gelatin having a bloom value of 50 to 190 and wherein the seamless capsule has a capsule shell-dissolution time of 60 seconds or less when the dissolution time is determined by a disintegration test using water as a test solution.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: December 6, 2016
    Assignee: MORISHITA JINTAN CO., LTD.
    Inventors: Ryosei Kamaguchi, Osami Nakano, Hisaaki Hatanaka
  • Patent number: 9499719
    Abstract: A process allowing the encapsulation of a polymerization accelerator comprising the steps of: a) providing an reverse emulsion containing, in an oil phase, a water solution/dispersion containing the polymerization activator, the oil phase including a heat curable mixture of an isocyanate and a polyalkyldiene hydroxylated or polyol, b) pouring the reverse emulsion in a water phase to make a multiple emulsion water/oil/water, containing drops of activators as the internal water phase, and then, c) heating the multiple emulsion obtained in step b) at a temperature of between 50 and 95° C., in order to cure the polyisocyanate in polyurethane and obtain drops of activator enclosed in shells of polyurethane dispersed in water. The invention also relates to aqueous gelling systems comprising the encapsulated polymerization accelerator with water soluble or dispersable monomers and a polymerization initiator dispersed in said monomers, useful i.a.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: November 22, 2016
    Assignee: RHODIA OPERATIONS
    Inventors: Arnaud Cadix, Rabih Rached, Pierre Ardaud
  • Patent number: 9498411
    Abstract: The present invention relates to perfume-containing microcapsules having both an aqueous inner phase and an oily inner phase, which can be used in home or personal care products, as well as to the process for producing these microcapsules and the consumer products comprising them.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: November 22, 2016
    Assignee: Firmenich SA
    Inventors: Lahoussine Ouali, Marlène Jacquemond
  • Patent number: 9445994
    Abstract: The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles comprise terminal-cysteine-bearing antigens or cysteine-modified antigens, at their surface and/or internally.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: September 20, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Jaehyun Moon
  • Patent number: 9402922
    Abstract: The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: August 2, 2016
    Assignee: COSMO TECHNOLOGIES INC.
    Inventors: Luigi Moro, Mauro Severino Ajani, Roberto Villa, Giuseppe Celasco, Alessandro Repici
  • Patent number: 9402923
    Abstract: The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: August 2, 2016
    Assignee: COSMO TECHNOLOGIES INC.
    Inventors: Luigi Moro, Mauro Severino Ajani, Roberto Villa, Giuseppe Celasco, Alessandro Repici
  • Patent number: 9387262
    Abstract: The present invention is related to a lipid composition comprising at least a first lipid component, at least a first helper lipid, and a shielding compound which is removable from the lipid composition under in vivo conditions.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: July 12, 2016
    Assignee: SILENCE THERAPEUTICS GMBH
    Inventors: Oliver Keil, Jorg Kaufmann
  • Patent number: 9339462
    Abstract: The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: May 17, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Darrell J. Irvine, Jaehyun Moon
  • Patent number: 9334422
    Abstract: The invention relates to a contact release capsule comprising a particle, a chemical payload, and a polymer coating, wherein the particle is impregnated with the chemical payload, and the chemical payload is held inside the particle by the polymer coating until the contact release capsule contacts a surface and a shearing force removes the polymer coating allowing the chemical payload to release outside the particle. The contact release capsule is useful in chemical mechanical planarization slurries. Particularly, the contact release capsule may comprise a glycine impregnated silica nanoparticle coated with a polymer, wherein the contact release capsule is dispersed in an aqueous solution and used in the copper chemical mechanical planarization process. Use of the contact release capsule in a slurry for copper chemical mechanical planarization may significantly improve planarization efficiency, decrease unwanted etching and corrosion, and improve dispersion stability.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: May 10, 2016
    Assignee: General Engineering & Research, L.L.C.
    Inventor: Robin Ihnfeldt
  • Patent number: 9322753
    Abstract: The present disclosure relates to a staining methodology employing a particle contrast agent composition capable of rapidly staining cells in a single step. The particle contrast agent composition can be comprised of a combination of one or more particle contrast agents and one or more permeabilizing agents, optionally including one or more fixing agents and other components. The particle contrast agent composition can include Crystal Violet, 5PD-Lytic, and Proclin 300.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: April 26, 2016
    Assignee: IRIS International, Inc.
    Inventor: Jack Cremins
  • Patent number: 9302794
    Abstract: A method produces and fills containers (1) made of thermoplastic plastic, in which an extruded plastic hose is inserted into an open mold having movable mold parts. The mold parts forming the container (1) are closed. The hose is expanded by a pressure gradient acting on the hose to form the container (1), preferably in the form of a bellows. The container is filled with filling material. The level of the filling material is raised by reducing container volume in the direction of the container opening. A container closure (5) for the container opening is formed from the hose by closing head jaws of the mold. In the region of the container closure (5), one section of the plastic hose remains unclosed to form a venting cannula (3). When the container volume is reduced, the level of the filling material is raised such that at least air is displaced from the container (1) through venting cannula (3). The venting cannula (3) is closed by closing auxiliary head jaws.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: April 5, 2016
    Inventor: Bernd Hansen
  • Patent number: 9291872
    Abstract: The present invention is directed to electrophoretic displays comprising microcups of a first shape and the microcups of a second shape, wherein each of the microcups of the first shape is surrounded by the microcups of the second shape, and the second shape is 90% or less of the first shape in area. The present electrophoretic displays comprise novel microcup designs, which may reduce the appearance of defects in the display images.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: March 22, 2016
    Assignee: E INK CALIFORNIA, LLC
    Inventors: Craig Lin, Robert A. Sprague
  • Patent number: 9079152
    Abstract: The invention provides a process for the preparation of essential oil microcapsules comprising dissolving a di- or polyisocyanate into an essential oil, emulsifying the resulting mixture in an aqueous solution containing a di- or polyamine, and or a di or polyhydroxy compound to effect encapsulation of said essential oil through interfacial polymerization, whereby there is formed a polyurea and/or polyurethane film around the essential oil droplets which film enhances the stability of said essential oil, reduces its evaporation rate and controls its release rate when applied to a substrate.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: July 14, 2015
    Assignee: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
    Inventors: Arie Markus, Charles Linder
  • Patent number: 9061268
    Abstract: The invention generally relates to the ultrasmall MOx nanoparticles that are made in a solvothermal method using water soluble inorganic ammonium salt precursors of the MOx and organic amines, and slow heating to generate uniform ultrasmall MOx nanoparticles of 5 nm or less, as well as methods to make and use same.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: June 23, 2015
    Assignee: William Marsh Rice University
    Inventors: Nikolaos Soultanidis, Michael S. Wong
  • Publication number: 20150115487
    Abstract: Encapsulated solids are made by first encapsulating precursor materials in a polymer shell. The precursors are some combination of solids, liquids, gases, and/or gels. The precursors are then transformed into solids by emplacement of the capsule in an environment where gas or fluid transport into or out of the polymer shell causes transformation into solids.
    Type: Application
    Filed: October 29, 2013
    Publication date: April 30, 2015
    Applicant: Lawrence Livermore National Security, LLC
    Inventors: William L. Bourcier, III, Roger D. Aines, Sarah E. Baker, Eric B. Duoss, Amitesh Maiti, Jeffery J. Roberts, Christopher M. Spadaccini, Joshuah K. Stolaroff, John J. Vericella, Jennifer A. Lewis, James O. Hardin, IV, William C. Floyd, III
  • Patent number: 8992196
    Abstract: A seamless capsule manufacturing apparatus (1) manufactures a seamless capsule by means of nozzles (2a-2d). A core liquid (5) and a coating liquid (6) are supplied to each of the nozzles (2a-2d) from pumps (16, 18) through distributors (21, 22). The distributors (21, 22) and the nozzles (2a-2d) are connected to each other by core liquid distributing tubes (23a-23d) and coating liquid distributing tubes (25a-25d), and each of the core liquid distributing tubes (23a-23d) and each of the coating liquid distributing tubes (25a-25d) have the same length. A vibrator (24) is mounted to the distributor (21), and the core liquid (5) is supplied to the nozzles (2a-2d) while being vibrated. Each of the distributors (21, 22) is provided with an air vent device (35), and air vent is performed appropriately.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: March 31, 2015
    Assignee: Freund Corporation
    Inventors: Masayuki Ikeda, Hiroshi Nagao
  • Publication number: 20150086613
    Abstract: Disclosed herein are novel lipids and liposomal compositions prepared using such compounds and related methods of neutralizing or otherwise modifying such liposomal compositions. The lipids described herein are useful for example, as liposomal vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and the subsequent transfection of such target cells. In certain embodiments, one or more of the compounds that comprise the liposomal delivery vehicle may be neutralized or further modified such that the properties of the liposomal delivery vehicle are modified.
    Type: Application
    Filed: March 29, 2013
    Publication date: March 26, 2015
    Inventors: Frank DeRosa, Braydon Charles Guild, Michael Heartlein
  • Publication number: 20150079290
    Abstract: The disclosure provides a poly(urea-formaldehyde) microcapsule, which comprises encapsulated in the poly(urea-formaldehyde) microcapsule an organofluorine silane of the general formula (I) A3C(CA2)xSiR1yX(3-y) (I), wherein in formula (I) A is either fluorine (F) or hydrogen (H), wherein at least 50% of atoms A are fluorine. X is chloro or a group RO, wherein R is a linear or branched alkyl radical of 1 to 4 carbon atoms, R1 is a linear, branched or cyclic alkyl group of 1 to 8 carbon atoms, n=0 or 2, y=0 or 1 or 2 and m=0 to 20, encapsulated within the microcapsule. The disclosure also provides self-healing coating compositions comprising such polymeric microcapsules and methods of preventing or slowing corrosion using such coating compositions.
    Type: Application
    Filed: March 13, 2013
    Publication date: March 19, 2015
    Inventors: Jinglei Yang, Mingxing Huang
  • Publication number: 20150072146
    Abstract: The present invention relates to a method for preparing capsules comprising a liquid core, a stiffened intermediate envelope and a gelled external envelope, comprising a step of forming a multi-component liquid drop, a gelification step and a stiffening step. The present invention also relates to a method for preparing capsules comprising a liquid core and a stiffened envelope, comprising a step of forming a multi-component liquid drop, a gelification step, a stiffening step and a depolymerizing step.
    Type: Application
    Filed: January 31, 2013
    Publication date: March 12, 2015
    Applicant: CAPSUM
    Inventors: Jerome Bibette, Mathieu Goutayer
  • Publication number: 20150057210
    Abstract: The need for a stable, quick dissolving unit dose article delivering good fabric care benefit is met by combining a cationic polymer with a fatty acid or salt in a non-aqueous composition, that is comprised within a water-soluble or dispersible film. By combining the cationic polymer with the fatty acid, the cationic polymer is prevented from reducing the solubility of the encapsulating film.
    Type: Application
    Filed: November 7, 2014
    Publication date: February 26, 2015
    Inventors: Regine LABEQUE, Peter Jos Emma VAN GINDEREN, Marc JENNEWEIN
  • Publication number: 20150037427
    Abstract: The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either hydrophobic or hydrophilic, from stable nanoparticles of opposite characteristics. The protection of the active agent was achieved by loading the agent to be protected, into nanocarriers, which were subsequently encapsulated into sub-micron nanoparticles. The sub-micron nanoparticles formation has been successfully achieved by the use of novel nano spray techniques.
    Type: Application
    Filed: September 20, 2012
    Publication date: February 5, 2015
    Inventors: Simon Benita, Orit Amsalem, Taher Nassar
  • Publication number: 20150021800
    Abstract: Provided is a herbicidal composition comprising a herbicidally active compound selected from a difluoromethanesulfonylanilide compound represented by the general formula (I): wherein R1 represents a hydrogen atom, an alkyl group or an alkoxyalkyl group; or a salt thereof encapsulated in a microcapsule, or a herbicidal composition comprising the herbicidally active compound encapsulated in a microcapsule and a benzoic acid compound represented by the general formula (II): wherein R2 represents a hydrogen atom, an alkyl group having 1 to 15 carbon atoms, a hydroxyl group, a nitro group, or an amino group; and R3 represents a hydrogen atom, an alkali metal atom or an alkyl group. The herbicidal composition exert a pharmacological effect for a prolonged period of time, can alleviate or prevent any harmful effect and can reduce the environmental load.
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Inventors: Toshihiro IKEUCHI, Tetsuo OHKAWA
  • Patent number: 8927009
    Abstract: A pharmaceutical capsule comprises a shell having encapsulated therewithin a liquid solution of ABT-263 or a pharmaceutically acceptable salt thereof in a substantially non-ethanolic carrier that comprises as pharmaceutically acceptable excipients (a) at least one phospholipid, (b) at least one solubilizing agent for the at least one phospholipid, selected from the group consisting of glycols, glycerides and mixtures thereof, (c) at least one non-phospholipid surfactant and (d) at least one sulfur-containing antioxidant. The capsule is useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: January 6, 2015
    Assignee: AbbVie Inc.
    Inventors: Ping Tong, Deliang Zhou, Geoff G. Z. Zhang, Katherine R. Heemstra, Cristina M. Fischer, Nathaniel D. Catron, Eric A. Schmitt, Yeshwant D. Sanzgiri
  • Publication number: 20140377333
    Abstract: A method of making dietary supplement compositions includes generating an aqueous phase, generating an oil phase, performing a first homogenizing step by mixing the aqueous and oil phases, adding reduced glutathione to the aqueous-oil composition and performing a second homogenizing step by mixing the aqueous-oil composition and reduced glutathione, adding a first flavor to the aqueous-oil-glutathione composition, performing a third homogenizing step by mixing the aqueous-oil-glutathione composition and the first flavor, adding xanthan gum dispersed with glycerin to the aqueous-oil-glutathione-first-flavor composition and performing a fourth homogenizing step by mixing the aqueous-oil-glutathione-first-flavor composition and xanthan gum; adding a second flavor to the aqueous-oil-glutathione-first-flavor-xanthan composition and performing a fifth homogenizing step by mixing the aqueous-oil-glutathione-first-flavor-xanthan composition and the second flavor so as to form a dietary supplement composition.
    Type: Application
    Filed: December 18, 2013
    Publication date: December 25, 2014
    Applicant: ZEOLIFE INC.
    Inventors: James John YIANNIOS, Subhash KEKATPURAY
  • Publication number: 20140347718
    Abstract: The invention provides an electrophoretic medium comprising at least two types of particles having substantially the same electrophoretic mobility but differing colors. The invention also provides article of manufacture comprising a layer of a solid electro-optic medium, a first adhesive layer on one surface of the electro-optic medium, a release sheet covering the first adhesive layer, and a second adhesive layer on an opposed second surface of the electro-optic medium.
    Type: Application
    Filed: August 13, 2014
    Publication date: November 27, 2014
    Inventors: Gregg M. Duthaler, Karl Raymond Amundson, Barrett Comiskey, Holly G. Gates, Alberto Goenaga, John E. Ritter, Michael L. Steiner, Russell J. Wilcox, Robert W. Zehner, Anthony Edward Pullen
  • Publication number: 20140342858
    Abstract: A spherical pellet marking round for gas propelled guns, such as airsoft electric guns and gas blow back guns, allows a user or military/law enforcement trainees to actually when they hit their opponent. The marking round is heavier than conventional gas propelled gun rounds, allowing for more reliable breaking on target. The marking round has a hard, brittle shell and is sized for the gun or rifle type. The marking round can include colored marking material, ultraviolet, infrared, forward looking infrared (FLIR) and luminous “glow-in-the-dark” shells for tracer versions. An oversized wedge can be used in production that allows for heavier weighted fill material to be used.
    Type: Application
    Filed: May 14, 2013
    Publication date: November 20, 2014
    Inventor: Kerry Thaddeus Bowden
  • Publication number: 20140336284
    Abstract: Disclosed is a powder antifoaming agent containing: (A) a hydrophobic organopolysiloxane that has a viscosity at 25° C. of 10-100,000 mm2/s; (B) a fine silica powder; (C) a surfactant; and (D) a water-soluble encapsulating agent that is in a solid state at 25° C. This powder antifoaming agent is characterized by being obtained by spray drying a dispersion liquid that is obtained by dispersing a silicone oil compound, which is obtained by mixing the component (A) and the component (B), and the component (D) in water in the presence of the component (C), and is also characterized in that the silicone oil compound is encapsulated by the component (D) that serves as an outer shell. Since the present powder antifoaming agent does not contain water by being produced by a spray drying method, the powder antifoaming agent is free from problems of emulsion antifoaming agents such as separation and putrefaction.
    Type: Application
    Filed: October 18, 2012
    Publication date: November 13, 2014
    Inventors: Takato Sakurai, Shinji Irifune
  • Patent number: 8859003
    Abstract: Hydrophobic liquids are microencapsulated by an enteric matrix in an environment substantially free of organic solvents. The process includes forming an emulsion of the enteric material and hydrophobic liquid in water, titrating the emulsion with an acid to form a particulate precipitate and optionally coating the particulate with a combination of enteric material and plasticizer.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: October 14, 2014
    Assignee: Intercontinental Great Brands LLC
    Inventors: Ahmad Akashe, Anilkumar Ganapati Gaonkar, Les Lawrence, Amado R. Lopez, George W. Haas, Dana Sebesta, Yan Wang
  • Patent number: 8852472
    Abstract: The present invention is related to a lipid composition comprising at least a first lipid component, at least a first helper lipid, and a shielding compound which is removable from the lipid composition under in vivo conditions.
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: October 7, 2014
    Assignee: Silence Therapeutics GmbH
    Inventors: Oliver Keil, Jörg Kaufmann
  • Publication number: 20140234411
    Abstract: The present invention is related to a seamless capsule which easily dissolves in the oral cavity etc. The present invention provides a seamless capsule comprising a capsule content solution, and a capsule shell enclosing the capsule content solution, wherein the capsule shell comprises a gelatin having a bloom value of 50 to 190 and wherein the seamless capsule has a capsule shell-dissolution time of 60 seconds or less when the dissolution time is determined by a disintegration test using water as a test solution.
    Type: Application
    Filed: September 21, 2012
    Publication date: August 21, 2014
    Inventors: Ryosei Kamaguchi, Osami Nakano, Hisaaki Hatanaka
  • Publication number: 20140221961
    Abstract: A nano-carrier comprising an antiproliferative drug encapsulated by a lipophilic enhancement agent.
    Type: Application
    Filed: February 7, 2014
    Publication date: August 7, 2014
    Inventor: Juan Granada
  • Publication number: 20140174684
    Abstract: Expandable microspheres formed by suspension polymerization using a shot growth method are provided. The microspheres are formed of a continuous, gas impermeable shell surrounding a blowing agent. The shell includes a first polymer layer formed from primary monomers and a second layer that includes a chemically reactive monomer or a high Tg monomer. To form the microspheres, the primary monomers are polymerized in a reaction vessel to an approximate 90% polymerization, at which time a secondary monomer that is either a monomer having a Tg of at least 85° C. or a chemically reactive monomer, is added to the reaction vessel to drive the polymerization reaction to completion. The outer layer thus contains either a larger amount of the high Tg monomer or a chemically reactive monomer that possesses the ability to covalently bond a cationic species. The microspheres may be used in papermaking processes to increase the paper bulk.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: INTERNATIONAL PAPER COMPANY
    Inventors: YAOLIANG HONG, KOSARAJU KRISHNA MOHAN, VICTORIA LAURENTIA DIMONIE, MARK FAGAN, ANDREW KLEIN, ERIC SCOTT DANIELS, BRIAN BOYARS, PETER M. FROASS, CHRISTOPHER D. ANDERSON, EDWARD DAVID SUDOL
  • Patent number: 8741337
    Abstract: An encapsulated material containing an oxidation-sensitive core is covered by at least a dried phospholipid layer, and contains at least one phytosterol in the core, the phospholipid layer or in a further layer or layers. By using microencapsulation, oxidatively unstable materials may be provided with a synthetic protective barrier and rendered less susceptible to oxidative degradation.
    Type: Grant
    Filed: January 2, 2009
    Date of Patent: June 3, 2014
    Assignee: Aveka, Inc.
    Inventors: William A. Hendrickson, John M. Finney, Olaf C. Moberg, Christopher J. Rueb, Robert G. Bowman, Chetan S. Rao, Nita M. Bentley