Abstract: An encapsulated material containing an oxidation-sensitive core is covered by at least a dried phospholipid layer, and contains at least one phytosterol in the core, the phospholipid layer or in a further layer or layers. By using microencapsulation, oxidatively unstable materials may be provided with a synthetic protective barrier and rendered less susceptible to oxidative degradation.

Abstract: This invention relates to single solvent polymer extraction methods.

Abstract: The present invention relates to innovative antifouling additives, to a process for producing them, to coating systems comprising the antifouling systems of the invention, to a process for producing the coating systems, and to the use of the antifouling additives and coating systems of the invention for preventing the underwater fouling of surfaces of objects which are in contact or come into contact with water.

Abstract: Lipobeads (liposome-encapsulated hydrogels) combine properties of hydrogels and liposomes to create systems that are sensitive to environmental conditions and respond to changes in those conditions in a fast time scale. Lipobeads may be produced by polymerizing anchored or unanchored hydrogels within liposomes or by mixing anchored or unanchored hydrogels with liposomes. Giant lipobeads may be produced by shrinking unanchored nanogels in lipobeads and fusing the resulting lipobead aggregates, long-term aging of anchored or unanchored lipobeads, or mixing anchored or unanchored aggregated nanogels with liposomes. Poly(acrylamide), poly(N-isopropylacrylamide), and poly(N-isopropylacrylamide-co-1-vinylimidazole) lipobeads were produced and characterized.

Abstract: Methods of nanoencapsulation are described herein. Embodiments of the method utilize the coacervation of a cationic polyelectrolyte with an anionic polyelectrolyte to form a novel capsular matrix. In particular, the novel methods may be used to encapsulate a suspension of a hydrophobic material such as a carotenoid. The disclosed methods do not require lengthy pH adjustments nor do they require the use of any toxic crosslinking agents. In one embodiment, a method of encapsulation comprises dispersing a hydrophobic compound in an organic solvent to form a solution. The method also comprises admixing an anionic polyelectrolyte and a cationic polyelectrolyte with the suspension to form a mixture. In addition, the method comprises quiescently cooling the mixture so as to cause self-crosslinking of a capsular matrix encapsulating the hydrophobic particles.

Abstract: The present invention provides methods for microencapsulation of active ingredients for topical application, whereby double-layer and triple-layer microcapsules are obtained. The microcapsules protect the active ingredients, maintain their original activity throughout processing, formulation and storage, and enable controlled release of the active ingredient only upon application onto the skin.

Abstract: Encapsulation compositions in which an encapsulate (A) is encapsulated in a matrix (B) may be prepared by: (i) mixing matrix (B) with a liquid plasticizer and encapsulate (A) in an extruder, to obtain a melted mixture of encapsulate (A) and matrix (B); and (ii) extruding the melted mixture, to obtain an extruded mixture.

Abstract: A method for making hollow nanoparticles, comprises a) providing an amount of a polyelectrolyte having a charge, b) providing an amount of a counterion having a valence of at least 2, c) combining the polyelectrolyte and the counterion in a solution such that the polyelectrolyte self-assembles to form spherical aggregates, and d) adding nanoparticles to the solution such that nanoparticles arrange themselves around the spherical aggregates. The polyelectrolyte may have a positive or negative charge. The charge ratio R of total charge of the counterions to the total charge of the polyelectrolyte is greater than 1.0.

Abstract: A stabilized emulsion is mixed with plasticizable matrix material to produce shelf stable, controlled release, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitive encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component, such as a protein, to form an emulsion. The emulsion is admixed with a matrix material for obtaining a formable mixture or dough. An acidic antioxidant for prevention of oxidation of the active, sensitive encapsulant, and a plasticizer which solubilizes the acidic antioxidant are included in the matrix material which encapsulates film-coated oil droplets containing the readily oxidizable component.

Abstract: A stabilized emulsion is employed to produce shelf stable, controlled release, discrete, solid particles or pellets which contain an encapsulated and/or embedded component, such as a readily oxidizable component, such as omega-3 fatty acids. An oil encapsulant component which contains an active, sensitive encapsulant, dissolved and/or dispersed in an oil is admixed with an aqueous component and a film-forming component, such as a protein, to form an emulsion. The emulsion is admixed with a matrix material for obtaining a formable mixture or dough. An acidic antioxidant for prevention of oxidation of the active, sensitive encapsulant, and a plasticizer which solubilizes the acidic antioxidant are included in the matrix material which encapsulates film-coated oil droplets containing the readily oxidizable component. The plasticizer, such as glycerol, provides mobility for the acidic antioxidant within the matrix material of the pellets for reaction with any ambient oxygen and malodorous amines.

Abstract: A method of isolating a PHA, includes combining the PHA, a first solvent and a second solvent to form a combination, the first solvent being capable of forming an azeotrope with the second solvent; and heating the combination to form the azeotrope of the first and second solvents.

Abstract: A medical device includes a body, a member in the body, and a contrast agent in the member. The device can be visible by magnetic resonance imaging.

Abstract: Methods and compositions are provided for producing nucleic acid-based compositions. Methods include enzyme catalyzed or nucleic acid polymer conjugation. Compositions include nucleic acid-containing hydrogels which can be elongated via rolling circle amplification. The hydrogels can encapsulate bioactive agents for drug delivery.

Abstract: A sealing assembly for a liquid conveying system includes a first structure defining an aperture, such as a pipe receiving aperture. A second structure, such as a pipe is received in the aperture. And an annular seal is disposed within the aperture for radially sealing between the first structure and the second structure. The seal includes an outer radial portion embedded in the first structure and an inner radial portion in sealing engagement with the second structure. The inner radial portion defines an internal cavity containing a substantially incompressible fluid or gel that is movable within the cavity to provide a dynamic seal with the second structure.

Abstract: Apparatus to eject on demand discrete hollow microsphere droplets that are characterized by a highly regular and predictable spherical shape, devoid of tails or other irregularities common in the prior art with a selected pure gas contained in the center. With this method and apparatus, droplets may be formed of any suitable material including glass, ceramic, plastic, or metal. A variety of gases at various pressures including complete vacuums may be contained in the hollow microsphere. Microspheres filled with ionizable gas may be used as pixels in a plasma display panel. Microspheres used as a pixel elements may be referred to as Plasma-spheres. The inside of each Plasma-sphere may contain a luminescent material such as a phosphor and/or a secondary electron emission material such as magnesium oxide or a rare earth oxide introduced during the gas filling of the microsphere.

Abstract: The microspheres have many possible applications including smart drug delivery, breaking and damper devices. In one arrangement, a microsphere comprises a shell 120 and a core 110. The core comprises a liquid, which may be a drug, while the shell comprises magnetic particles. The microsphere is deformable in response to to application of an external magnetic field. Also disclose is an arrangement in which a microsphere has a magnetic core and a PDMS shell.

Abstract: An aqueous microcapsule suspension liquid exhibiting an excellent (long-term) storage stability and allowing easy re-dispersion and dilution with water even after such a storage, is produced by adding a microorganism-fermented polysaccharide of succinoglycan type as a thickening agent into a microcapsule slurry, or by adding such a microorganism-fermented polysaccharide as a thickening agent to a microcapsule slurry after uniform dilution with water.

Abstract: The invention relates to a method for impregnating a support matrix with solid and/or liquid compounds using a compressed gas or a compressed mixture of gases at densities ranging from 0.15 to 1.3 kg/l and at least two unsymmetrical pressure changes (pulsations). The method is further characterized in that both a multitude of impregnating substances such as biologically active compounds, technical materials or metal-organic compounds, as well as support matrices of biological origin and organic or inorganic substances can be used that have large inner surfaces and/or inner surfaces that are difficult to access.

Abstract: A microcapsule, a structure including a microcapsule, an article including a microcapsule and a method of preparing microcapsules provided, the microcapsule includes at least one material selected from the group consisting of a magnetic substance, a dielectric substance and a combination thereof. The microcapsule also includes a volatile material.

Abstract: Aqueous dispersion containing a metal oxide powder with a fine fraction and a coarse fraction, in which—the metal oxide powder is silicon dioxide, aluminum oxide, titanium dioxide, zirconium dioxide, cerium oxide or a mixed oxide of two or more of the aforementioned metal oxides,—the fine fraction is present in aggregated form and has a mean aggregate diameter in the dispersion of less than 200 nm,—the coarse fraction consists of particles with a mean diameter of 1 to 20 ?m, —the ratio of fine fraction to coarse fraction is 2:98 to 30:70, and—the content of metal oxide powder is 50 to 85 wt. %, referred to the total amount of the dispersion. The aqueous dispersion is produced by a process comprising the steps:—production of a fine fraction dispersion by dispersing the pulverulent fine fraction in water by means of an energy input of at least 200 KJ/m3?, and—introducing the coarse fraction in the form of a powder into the fine fraction dispersion under dispersing conditions at a low energy input.

Abstract: A reagent delivering article comprising porous sintered polycrystalline diamond where the delivering article is capable of retaining at least one chemical reagent and releasing the chemical reagent in a fluid or has reactive sites on diamond surfaces of the article.

Abstract: The present disclosure relates to a method of melt processing an active agent. The method may include encapsulating an active agent in a first polymer material exhibiting a first processing temperature T1 and forming capsules including the active agent. The method may also include melt processing the capsules with a second polymer material exhibiting a second processing temperature T2, wherein T1>T2.

Abstract: The present invention relates to a method for preparing a suspension for the encapsulation of heat and moisture sensitive substances in capsules, sachets, droplets and food compositions. It also relates to methods for encapsulating, to the encapsulated products and to methods for storing the encapsulated products. The invention is extremely suitable for the encapsulation of microbial cultures. Cultures encapsulated in capsules prepared according to the method of the invention, will stay stable for a long time. At 25 degrees C. they show a stability reduction of less than 1 log per month.

Abstract: To stabilize the supply of color material particles as well as reduce the wasteful amount of color material particles used and suppress deformation or damages of the outer walls of a plurality of cell regions partitioned by partition walls provided upright, an interval holding section having a first height dimension for holding an interval between a non-display area of the surface of a substrate for a display panel, which has an electrode at each of the cell regions, and a non-transfer area of the surface of an electrophotographic transfer body, is provided between the non-display area of the surface of the substrate and the non-transfer area of the surface of the transfer body, at a predetermined value at the time when the transfer body transfers the color material particles to the substrate, and the color material particles are transferred to the substrate from the transfer body while biasing the substrate toward the transfer body in such a way that the interval holding section holds the interval between th

Abstract: Methods of using microchannel separation systems including absorbents to improve thermal efficiency and reduce parasitic power loss. Energy is typically added to desorb a solute and then energy or heat is removed to absorb a solute using a working solution. The working solution or absorbent may comprise an ionic liquid, or other fluids that demonstrate a difference in affinity between a solute and other gases in a solution.

Abstract: The invention concerns a gel covering of a patient interface. This gel covering has a mask connection area by which its side that faces away from the patient is joined with a mask body. The patient interface can be designed, for example, as a respiratory mask. On its side that faces the patient's face, the respiratory mask has thin, inwardly formed, peripheral contact lips. The respiratory mask has accessories that allow it to be fastened on the patient's head as well as a hose connection for supplying air. At least one region formed from a filler is placed in or on the walls of the gel covering. The method is used to produce the gel covering of the invention.

Abstract: A method of making core-shell capsules containing a water-immiscible liquid, comprising the steps of (a) dispersing into the water-immiscible liquid a crosslinking agent that is inactive under the conditions of the dispersion; (b) emulsifying the resulting dispersion into an aqueous solution of a crosslinkable hydrocolloid; and (c) activating the crosslinking agent to cause the hydrocolloid to crosslink at the dispersion/solution interface. The method is simple and provides capsules that can be cold-loaded.

Abstract: A system that incorporates teachings of the present disclosure may include, for example, an apparatus having an outer nozzle operable to discharge an outer stream of a shell solution, and an inner nozzle operable to discharge an inner stream of a core solution intermixed with a plurality of materials. The outer stream can substantially surrounds the inner stream, thereby forming a combined stream. A plurality of capsules can be formed responsive to a force applied to the combined stream. At least a portion of the plurality of capsules are desirable capsules, each having a core encapsulated by a portion of the shell solution. The core can have at least one of the plurality of materials encapsulated by a portion of the core solution without protruding an outer surface of the portion of the shell solution. Additional embodiments are disclosed.

Abstract: A seamless capsule includes a core and a shell, wherein the core includes at least one polyunsaturated fatty acid, and at least one flavouring component, the process for manufacturing the capsule and products containing the capsule are also disclosed.

Abstract: Lipobeads (liposome-encapsulated hydrogels) combine properties of hydrogels and liposomes to create systems that are sensitive to environmental conditions and respond to changes in those conditions in a fast time scale. Lipobeads may be produced by polymerizing anchored or unanchored hydrogels within liposomes or by mixing anchored or unanchored hydrogels with liposomes. Giant lipobeads may be produced by shrinking unanchored nanogels in lipobeads and fusing the resulting lipobead aggregates, long-term aging of anchored or unanchored lipobeads, or mixing anchored or unanchored aggregated nanogels with liposomes. Poly(acrylamide), poly(N-isopropylacrylamide), and poly(N-isopropylacrylamide-co-1-vinylimidazole) lipobeads were produced and characterized.

Abstract: A microfluidic system for performing interfacial reactions can comprise at least one pump in fluid communication with a tube. A first fluid is injected into the tube so that its flow is laminar and continuous. A second fluid is injected in discrete amounts into the tube into the stream or flow of the first fluid. In other embodiments, discrete amounts of the second fluid are introduced into the channel first, then the first fluid is injected so that it creates a region of substantially laminar fluid flow around the discrete amounts of the second fluid. After the two fluids are in contact, a reaction occurs. The system can be configured so that the second fluid solidifies to form a capsule around the first fluid or vice versa. Other interfacial reactions also can be accomplished using the disclosed microfluidic systems and methods.

Abstract: The invention relates to a process for manufacturing a seamless breakable capsule, comprising—co-extruding an external and hydrophilic liquid phase, and an internal and lipophilic liquid phase, in order to form a capsule constituted of a core comprising the internal and lipophilic phase, and a shell comprising the external and hydrophilic phase,—immersing into an aqueous solution containing a curing agent, wherein the external liquid phase includes a gelling agent comprising gellan gum alone or in combination with another gelling agent, a filler, and a divalent metal sequestering agent, and to breakable capsules comprising a core and a shell, wherein the shell includes a gelling agent comprising gellan gum alone or in combination with another gelling agent, a filler, and a divalent metal sequestering agent.

Abstract: The present invention provides methods for isolating a PHA. The method comprises combining the PHA, a first solvent and a second solvent to form a combination, the first solvent and the second solvent being capable of forming an azeotrope with the second solvent; and heating the combination to substantially remove the first solvent from the combination. Alternatively, the method comprises combining the PHA, a first solvent, a second solvent and a third solvent to form a combination, the first solvent and the second solvent being capable of forming an azeotrope with the third solvent; and heating the combination to substantially remove the first solvent and the second solvent from the combination.

Abstract: There is provided a method of forming a barrier over a polar liquid phase or a non-polar liquid phase including the steps of: providing a liquid system including the polar liquid phase or non-polar liquid phase and a monomer having a hydrophilic portion and a hydrophobic portion, monomer being located at one or more boundaries of the polar liquid phase or non-polar liquid phase; and polymerising the monomer so as to form a polymeric barrier at the one or more boundaries.

Abstract: Dry liquids having a particle size distribution (cumulative undersize) D10% ?80 to 140 ?m D50% 140 to 200 ?m D90% 190 to 340 ?m are prepared by passing the liquids and a hydrophobic, pyrogenically prepared silica through a clearly defined, spatially limited shear zone in which the liquids are broken up into small droplets and are surrounded by the hydrophobic, pyrogenically prepared silica.

Abstract: Methods of encapsulating a substance including mixing a monomer with the substance to form a desired shape, and polymerizing the monomer.

Abstract: Disclosed herein are compositions, methods, and devices related to bilayer and monolayer membranes, their encapsulation in a hydrogel, and their formation. Methods of using the disclose compositions and devices are also disclosed.

Abstract: Exemplary electrophoretic ink capsules for electrophoretic displays, and methods for making the exemplary electrophoretic ink capsules are disclosed. In various embodiments, the electrophoretic ink capsules can include triboelectrically charged electrophoretic particles having higher electrical conductivity than conventionally charged electrophoretic particles allowing fabrication of electrophoretic displays with lower switching fields and faster response times.

Abstract: The present invention discloses a molded article with an antimicrobial property, and a manufacturing method thereof which can prevent contact of bacteria or viruses by combining the Kimchi lactic acid bacteria culture fluid having antibacterial and antivirus effects with a raw material to mold the article. The molded article needing the antimicrobial effect is provided with the antimicrobial property, by using the Kimchi lactic acid bacteria culture fluid with a wide antibacterial spectrum singly or in combination with nano metal particles. The Kimchi lactic acid bacteria culture fluid is combined in the molding step of the article, for reducing the manufacturing time and simplifying the manufacturing process.

Abstract: A composition comprising a material at least partially enclosed by a tubular, spherical or planar nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.

Abstract: A smoking device includes a recipient or able to receive burning products, preferably tobacco, and a filter element connected to the recipient, wherein the filter includes at least one breakable capsule, the capsule having a initial crush strength from 0.5 to 2.5 kp, and keeping a crush strength from 0.5 to 2.5 kp and a deformation of less than two third of its diameter prior to rupture after having been submitted to a smoking test. The invention is also relating to the capsule suitable for being incorporated in a smoking device, and to the process of manufacture of the capsule.

Abstract: The present invention relates, for example, to a stimulus-indicating device. More particularly, the present invention includes an apparatus for evidencing when a stimulus sensitive product has been exposed to a designated or predetermined stimulus for a certain period of time, and the invention further may include a method for manufacturing aspects of that apparatus.

Abstract: This invention discloses methods to dispense adhesives for fabricating electrooptic devices. In addition the invention also discloses on how the cavities of these electrooptic devices may be filled using detachable tabs. The Electrooptic devices of this invention may comprise liquid or solid electrolytes.

Abstract: A display device including: a first substrate having a pixel electrode; a second substrate having a common electrode; a microcapsule sandwiched between the first substrate and the second substrate; and a display material changing its optical characteristic in response to an electrical stimulation, the display material being encapsulated in the microcapsule, the microcapsule being selectively disposed on a display area formed by the pixel electrode in between the first substrate and the second substrate, and a background area of one of the first substrate and the second substrate being colored with a background color, the background area serving as a background with respect to the display area.

Abstract: The invention provides a method for encapsulating a liquid, which method comprises the steps of providing a suspension of droplets of the liquid to be encapsulated; stabilizing the suspension of droplets with a surfactant; adding a layered inorganic material to the stabilized suspension; and subjecting the suspension to a treatment which establishes that a shell of a hybrid material is formed around the droplets, which hybrid material comprises at least part of the inorganic material and at least part of the surfactant. The invention further provides encapsulated liquid droplets obtainable by said method.

Abstract: A method for encapsulating cisplatin and other positively-charged drugs into liposomes having a different lipid composition between their inner and outer membrane bilayers is disclosed. The liposomes are able to reach primary tumors and their metastases after intravenous injection to animals and humans. The encapsulated cisplatin has a high therapeutic efficacy in eradicating a variety of solid human tumors including but not limited to breast carcinoma and prostate carcinoma. Combination of the encapsulated cisplatin with encapsulated doxorubicin or with other antineoplastic drugs are claimed to be of therapeutic value. Also of therapeutic value in cancer eradication are claimed to be combinations of encapsulated cisplatin with a number of anticancer genes including but not limited to p53, IL-2, IL-12, angiostatin, and oncostatin encapsulated into liposomes as well as combinations of encapsulated cisplatin with HSV-tk plus encapsulated ganciclovir.

Abstract: In a sheet forming part 2 of a soft capsule manufacturing apparatus 1, a drum drive system 27 which forms a gelatin sheet 13, and a pickup roller drive system 28 which peels off the gelatin sheet 13 are constructed to drive separately from each other. In the drum drive system 27, a film-sheet forming drum 23 is driven by a first motor 271, while in the pickup-roller drive system 28, a pickup roller 24 is driven by a second motor 281.

Abstract: A system for producing a hot-filled softgel capsule utilizes a chilled liquid. The chilled liquid is routed through a chilled liquid conveyor tray into a chilled liquid bath. The chilled liquid conveyor tray directs the flowing chilled liquid into a flowing chilled liquid layer. Softgel capsules having a heated fill material are deposited in the flowing chilled liquid layer. The chilled liquid layer cools the capsule by transferring heat from the capsule to the chilled liquid. The flowing chilled liquid layer transports the capsule out of the chilled liquid conveyor tray into a chilled liquid bath. A capsule transfer conveyor transports the capsule out of the chilled liquid bath to a chilled liquid removal device. The chilled liquid removal device removes the chilled liquid from the capsule.

Abstract: A multi-headed ink-jet system adapted to eject encapsulated liquids is provided, which includes a plurality of concentric piezoelectric members. Each concentric piezoelectric member has a chamber configured to carry a liquid therethrough, and each concentric piezoelectric member is in liquid communication with an exit port provided in a concentric orifice. When each concentric piezoelectric member is actuated, a liquid contained in its chamber is moved near or through the concentric orifice. The plurality of concentric piezoelectric members cooperate to control the ejection of liquids through the concentric orifice to permit one liquid to be encapsulated by another liquid to form an encapsulated droplet. A method of operating a multi-headed ink-jet system adapted to eject encapsulated liquids.

Abstract: An electrophoretic display device of the present invention is formed of a first substrate, a second substrate, and microcapsules which are accommodated between these substrates and which contain an electrophoretic dispersion, wherein each of the microcapsules has an opening in at least a part thereof.