Abstract: To provide a composition for a three-dimensional integrated circuit capable of forming a filling interlayer excellent in thermal conductivity also in a thickness direction, using agglomerated boron nitride particles excellent in the isotropy of thermal conductivity, disintegration resistance and kneading property with a resin. A composition for a three-dimensional integrated circuit, comprising agglomerated boron nitride particles which have a specific surface area of at least 10 m2/g, the surface of which is constituted by boron nitride primary particles having an average particle size of at least 0.05 ?m and at most 1 ?m, and which are spherical, and a resin (A) having a melt viscosity at 120° C. of at most 100 Pa·s.

Abstract: A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta- or alpha-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved so as to release the microspheres from the polymer matrix. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding or minimizing undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method.

Abstract: This invention relates to a mass preparation method of spherical natural color wax beads and according to the invention, the beads have a higher specific gravity than water so that the beads do not flow into the sea and they are biodegradable to fundamentally remarkably reduce marine ecosystem contamination, and it enables mass preparation by significantly improving the previous preparation of spherical natural color wax beads which had difficulties in their mass preparation while using expensive equipment.

Abstract: A method of preparing transparent or nontransparent silica aerogel granules. The method includes forming a granular wet gel by spraying a silica sol into alcohol, the silica sol being prepared by mixing a water glass solution or an opacifier-containing water glass solution with an inorganic acid solution, forming a granular alcohol gel through gelation aging and solvent substitution of the granular wet gel in alcohol, hydrophobically modifying the surface of the granular alcohol gel using an organic silane compound, and drying the surface modified gel at ambient pressure or in a vacuum. The method may prepare silica aerogel granules in a short period of time through heat treatment at a relatively low temperature and at ambient pressure or in a vacuum, thereby ensuring excellent economic feasibility, continuity and reliability, suited for mass production.

Abstract: Provided is a glucose sensor. The glucose sensor according to the present invention includes noble metal-graphene composites, and has high sensitivity and significantly excellent current flow as compared to titanium dioxide-graphene composites. In addition, the noble metal-graphene composite manufactured by aerosol spray pyrolysis serves as an improved glucose sensor having desirable sensitivity, stability, reproducibility, and selectivity.

Abstract: According to the present invention, a polyvinyl butyral resin pellet is provided that gives off little odor when produced and handled, as well as has a high apparent density and favorable handleability. The present invention includes a method for producing a polyvinyl butyral resin pellet including the steps of: melting polyvinyl butyral resin powder with a water content of 0.01 to 6 wt % by means of a melt extruder that has at least one vent portion for devolatilization equipped with vacuum means, and cutting the melt of the polyvinyl butyral resin after extrusion of it from the melt extruder. The present invention further includes a polyvinyl butyral resin pellet having a total content of butyl aldehyde and 2-ethyl-2-hexenal of 100 ppm or less.

Abstract: A process for obtaining granules for manufacturing a silicon carbide based sintered product, includes a) mixing a powder of silicon carbide SiC particles, whose average diameter d50 is at least about 2 micrometers with a powder of a boron compound particles, whose average diameter d50 is at least about 2 micrometers, the SiC particles content being more than 90% by weight of the powder mixture; b) co-milling the powder mixture until the overall average diameter d50 of the resulting particles is between 0.3 and 1 micrometers; c) chemically treating the powder mixture by base solution and acid wash; d) mixing the powder mixture of c) with 1 to 10% by weight, based upon the silicon carbide content, of a carbon containing resin having a water miscibility of more than 10:50, as measured according to the ISO8989 standard, and e) spray-drying the resulting mixture of d), to generate the granules.

Abstract: A process for making cross-linked polysaccharide gels, particularly cross-linked hyaluronic acid gels, under basic conditions. The resulting gels possess improved degradation characteristics, and are useful in a variety of medical and cosmetic applications.

Abstract: The present invention provides methods for treating phytoglycogen-containing materials to generate phytoglycogen compositions with enhanced emulsification attribute. One method comprises contacting a phytoglycogen-containing material with at least one protease. The other method comprises heat treatment of a phytoglycogen-containing material, such as corn kernels. The two methods can be applied independently, or can be applied in combination. Applications of phytoglycogen compositions are also included.

Abstract: The present invention describes methods and tools for preparing a population of monodisperse polymer microparticles, which are of particular interest in the field of drug delivery.

Abstract: Spherical particles of one or more elemental metals and carbon are prepared from a precursor in the form of a metal oleate. The metal oleate precursor is dispersed in a liquid vehicle and aerosol droplets of the dispersed precursor are formed in a stream of an inert gas. The aerosol droplets are heated in the stream to decompose the oleate ligand portion of the precursor and form spherical particles that have a mesoporous nanocrystalline structure. The open mesopores of the spherical particles provide a high surface area for contact with fluids in many applications. For example, the mesopores can be infiltrated with a hydrogen absorbing material, such as magnesium hydride, in order to increase the hydrogen storage capacity of the particles.

Abstract: Polymeric particles having a size of about 0.1 to about 100 microns comprising at least two different phase separated polymers, at least one pigment, and at least one additive, where the pigment and additive are distributed within the phase separated polymers. Also disclosed are methods for preparing polymeric particles comprising phase separated polymers that comprise additives and pigments, wherein the methods involve molding.

Abstract: A composite material is formed by combining an expandable polymer having a charge with another polymer having an opposite charge to produce. In particular, the composite material can be prepared by combining the polymers with a medium such as and water, and expanding the mixture using a treatment that expands the mixture to produce, for example, insoluble porous foam-like composites.

Abstract: A particulate production apparatus, including a droplet discharger to discharge a liquid including a particulate element which is solidified to become a particulate; and a pressure controller to feed the liquid including a particulate element to the droplet discharger at a pressure within a desired range.

Abstract: Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.

Abstract: The present invention relates to pharmaceutical compositions comprising dapagliflozin and cyclodextrin, preferably (2-hydroxy)propyl-b-cyclodextrin or ?-cyclodextrin, preferably as inclusion complex. The invention further relates to a process for producing said pharmaceutical compositions. Finally, the invention relates to the use of cyclodextrin for producing dapagliflozin-containing dosage forms and to methods of purification of dapagliflozin.

Abstract: A flame spray pyrolysis method for making nanoscale, lithium ion-conductive ceramic powders comprises providing a precursor solution comprising chemical precursors dissolved in an organic solvent, and spraying the precursor solution into an oxidizing flame to form a nanoscale, lithium ion-conductive ceramic powder, wherein a concentration of the chemical precursors in the solvent ranges from 1 to 20 M. The precursor solution can comprise 1-20% excess lithium with respect to a stoichiometric composition of the ceramic powder. Nominal compositions of the nanoscale, ceramic powders are Li1.4Al0.4M1.6(PO4)3 where M is Ti or Ge.

Abstract: Inhalable pharmaceutical compositions can include an aqueous dispersion of particles including a hydrophobic bioactive agent (e.g., CoQIO) suitable for continuous aerosolization. Due to their chemical composition and methods of manufacture, the pharmaceutical compositions exhibit distinctive physicochemical properties that provide advantageous aerosol transmission and output.

Abstract: Methods of and devices for forming edge chamfers and through holes and slots on a material that is machined using a laser, such as an ultrafast laser. The shaped material has predetermined and highly controllable geometric shape and/or surface morphology. Further, a method of and a device for preventing re-deposition of the particles on a material that is machined using a laser, such as an ultrafast laser. A fluid is used to wash off the particles generated during the laser machining process. The fluid can be in a non-neutral condition, with one or more chemical salts added, or a condition allowing the coagulation of the particles in the fluid, such that the particles can be precipitated to avoid the reattachment to the machined substrate.

Abstract: A method and formulation for preparing spray dried vancomycin. In various embodiment, the formulation includes vancomycin HCl (10-20%) and one or more of the following PEG (0-5%), mannitol (0-5%), ethanol (0-10%), and a citrate buffer. Spray dried vancomycin has favorable reconstitution times and water content.

Abstract: Provided are foamed aromatic polyester-based resin particles for in-mold foam molding that have a long shelf life after production and can be used to produce an in-mold foam molded product having high mechanical strength and good appearance. The foamed aromatic polyester-based resin particles for in-mold foam molding contain an aromatic polyester-based resin and are characterized in that the content of residual carbon dioxide 7 hours after the particles are impregnated with carbon dioxide for 24 hours under the conditions of 25° C. and 1 MPa is 5% by weight or more.

Abstract: Provided by the present invention is an ethylene-vinyl alcohol copolymer resin composition having superior appearance characteristics (particularly decreased coloring and unevenness of the hue), and is accompanied by suppressed occurrence of yellowing, etc., in melt molding. An ethylene-vinyl alcohol copolymer resin composition containing an ethylene-vinyl alcohol copolymer (A) and a compound having an enediol structure (B), in which a molar ratio of the compound (B) to vinyl alcohol units of the ethylene-vinyl alcohol copolymer (A) is 2.70×10?9 or greater and 2.70×10?5 or less.

Abstract: In one aspect, pharmaceutical compositions comprising dispersions of an acid-sensitive drug and a neutral dispersion polymer are disclosed. The acid-sensitive drug has improved chemical stability relative to dispersions of the drug and acidic polymers. In another aspect, pharmaceutical compositions of low-solubility drugs and amphiphilic, hydroxy-functional vinyl copolymers are disclosed.

Abstract: Provided is a process for obtaining solid cellulose, such as a cellulose solidified article or cellulose shaped article, from a cellulose solution without causing discharge of large amounts of waste liquids and environmental issues such as large energy consumption. The process produces solid cellulose through the steps of (A) dissolving cellulose in a solvent (s1) to give a cellulose solution, where the solvent (s1) includes at least one onium hydroxide in a content of from 45 to 85 percent by weight and water in a content of from 15 to 55 percent by weight, and the at least one onium hydroxide is selected from the group consisting of quaternary phosphonium hydroxides and quaternary ammonium hydroxides; (B) bringing the cellulose solution into contact with a poor solvent (s2) to precipitate cellulose as a cellulose solidified article; and (C) separating and collecting the cellulose solidified article.

Abstract: The invention relates to remotely operated laser sintering systems and methods for manufacturing pellets containing highly radioactive elements. The highly radioactive elements can be recovered from used nuclear fuels. The systems and methods of the invention employ a feed composition including one or more highly radioactive elements and a ceramic matrix material. The feed composition is distributed in the form of a layer and sintered by directing at least one laser beam to form a pattern in the layer of the feed composition. The pattern corresponds to the shape of the pellet. Further, the sintering process can be repeated as necessary to achieve a pre-determined pellet height.

Abstract: A method is described including passing a solution having a biodegradable polymer, a solvent and a treatment agent through an electrocharged nozzle to form particles encapsulating the treatment agent. The particles emitted from the electrocharged nozzle may be exposed to a charge opposite that of the nozzle. The particles may be deposited in a collection assembly comprising a liquid phase. A further method including combining a biodegradable polymer, a solvent and a treatment agent to form a solution, electrodepositing the solution in a particle form wherein the particles encapsulate the treatment agent in a collection assembly comprising a liquid phase and mixing the particles with a bioerodable material capable of forming a gel is described. An apparatus having an electrocharged nozzle, a grounded electrode having an opposite charge to that of the nozzle and a collection assembly comprising a liquid phase is further disclosed.

Abstract: A method for producing a porous fuel including uranium, optionally plutonium, and optionally at least one minor actinide, the method including: a) compacting a mixture including a first type of agglomerate including uranium oxide in a form of uranium dioxide UO2, optionally plutonium oxide, and optionally at least one minor actinide oxide, and a second type of agglomerate including uranium oxide in a form of triuranium octaoxide U3O8, optionally plutonium oxide, and optionally at least one minor actinide oxide; b) reducing the compacted mixture in a reducing medium, to reduce all or part of the triuranium octaoxide U3O8 into uranium dioxide UO2, the second type of agglomerate being prepared prior to the compacting by a series of specific operations.

Abstract: A module comprising: one or more vials containing tritium; one or more tritium covers; and an open space within the one or more tritium covers, wherein the one or more vials containing tritium are located within the open space of the one or more tritium covers so that the one or more tritium covers protect the one or more vials containing tritium, and wherein the one or more tritium covers are made from a material that exhibits sufficient strength so that the module protects the one or more vials containing tritium from damage when dropped from a distance of 1 m or more.

Abstract: A method of producing particulate, including introducing an initial liquid including a particulate component in a lower concentration than that of a liquid including a particulate component or no concentration to a projection hole of a droplet projector so as to be projected at the start of the discharging; discharging a droplet of the liquid comprising a particulate component from the projection hole; and solidifying the droplet to form a particulate.

Abstract: Provided is an assembly including a block co-polymer film and a plurality of nano-rods; where the plurality of nano-rods are oriented at the surface of the block co-polymer film, substantially perpendicular to at least one interface between block co-polymer domains. Further provided are methods of assembly formation and devices including such assemblies.

Abstract: Provided are conducting polymer nanofibers, methods of making conducting polymer nanofibers, and uses thereof. The conducting polymer nanofibers can be formed by, for example, electrospinning, force spinning, and centrifugal spinning using a spinning dope. The conducting polymer nanofibers can be used in devices, such as a radiation detecting device.

Abstract: The invention relates to a method for the production of carrier pellets for pharmaceutical active substances. Likewise, the invention relates to such carrier pellets and also to pharmaceutical formulations containing these. The carrier pellets according to the invention are used for transporting and releasing pharmaceutical active substances, in particular in the human body.

Abstract: The subject invention provides a solid dispersion of rasagiline citrate, a composition and a process for the manufacture thereof.

Abstract: A process of producing ceramic-ceramic composites, including but not limited to nuclear fuels, and composites capable of exhibiting increased thermal conductivities. The process includes milling a first ceramic material to produce a powder of spheroidized particles of the first ceramic material, and then co-milling particles of a second ceramic material with the spheroidized particles of the first ceramic material to cause the particles of the second ceramic material to form a coating on the spheroidized particles of the first material. The spheroidized particles coated with the particles of the second ceramic material are then compacted and sintered to form the ceramic-ceramic composite, in which the second ceramic material forms a continuous phase completely surrounding the spheroidized particles of the first ceramic material.

Abstract: A method of treating functional dyspepsia and/or irritable bowel syndrome in mammals in need of treatment is disclosed herein. The method comprises administering to the mammal a formulation by inhalation, wherein the formulation avoids first pass metabolism of the active ingredient. The method comprises administering a formulation by pulmonary inhalation comprising a diketopiperazine and a glucagon-like peptide (GLP-1), analog, ROSE-010.

Abstract: A uranium dioxide nuclear fuel pellet has about 50 to about 400 ?M (with respect to a 3-dimentional size) microcells formed of a ceramic material having a chemical attraction with fission products generated in the nuclear fuel pellet to absorb and trap the fission products, such that the extraction of the fission product may be retrained in a normal operation condition and that the performance of the nuclear fuel may be enhanced by mitigating PCI. In addition, highly radioactive fission products including Cs and I having a large generation amount or a long half-life enough to affect the environments can be trapped in the pellet in an accident condition, without being released outside.

Abstract: Topical minocycline compositions with reduced fluorescence are provided. In some instances, the compositions include an amount of a minocycline active agent associated with porous calcium particles. Also provided are methods of using the compositions, e.g., in the treatment of acne.

Abstract: A nanocomposite thermoelectric conversion material includes a matrix and semiconductor nanowires dispersed as a dispersant in the matrix. The semiconductor nanowires are arranged unidirectionally in a long axis direction of the semiconductor nanowires.

Abstract: Silicon particles for active materials and electro-chemical cells are provided. The active materials comprising silicon particles described herein can be utilized as an electrode material for a battery. In certain embodiments, the composite material includes greater than 0% and less than about 90% by weight of silicon particles. The silicon particles have an average particle size between about 0.1 ?m and about 30 ?m and a surface including nanometer-sized features. The composite material also includes greater than 0% and less than about 90% by weight of one or more types of carbon phases. At least one of the one or more types of carbon phases is a substantially continuous phase.

Abstract: Composite particles for electrochemical device electrode which contain an electrode active material, a non-water soluble particle-shaped polymer, and a water-soluble polymer having a sulfonic acid group are provided. According to the present invention, composite particles for electrochemical device electrode are high in fluidity, exhibit high adhesion with a current collector, and can provide an electrochemical device electrode which is high in initial capacity, low in internal resistance, an excellent in high temperature storage characteristics are provided.

Abstract: A method of producing at least one of microscopic and submicroscopic particles includes providing a template that has a plurality of discrete surface portions, each discrete surface portion having a surface geometry selected to impart a desired geometrical property to a particle while being produced; depositing a constituent material of the at least one of microscopic and submicroscopic particles being produced onto the plurality of discrete surface portions of the template to form at least portions of the particles; separating the at least one of microscopic and submicroscopic particles comprising the constituent material from the template into a fluid material, the particles being separate from each other at respective discrete surface portions of the template; and processing the template for subsequent use in producing additional at least one of microscopic and submicroscopic particles.

Abstract: The invention relates to a fuel component and a method for manufacturing of a fuel component. The fuel component is adapted to be used in fission reactors. The fuel component comprises a core consisting of a first material, and a layer consisting of a second material. The layer encloses at least partly the core. The first material comprises a fissile substance. The fuel component comprises an intermediate layer between the core and the layer. The intermediate layer has a material gradient that comprises a decrease of the concentration of the first material from the core to the layer and an increase of the concentration of the second material from the core to the layer.

Abstract: A highly efficient process is disclosed for making proppants from generally non-spherical or discretized raw material, such as naturally occurring sand or pelletized refractory material. In one embodiment of the process, the discretized material is heated by a counter-current flow of hot gas in a first Moving Bed Gas-Solids Direct Contact Heat Exchanger (MBGSDCHX). The heated discretized material is then further heated to a transformative temperature by a raw material transformation means to a partially or fully melted state in which the discretized raw material assumes generally spherical shapes. The spheres are then cooled by a counter-current flow of cold gas in a second MBGSDCHX. The cooled spheres are then size-classified for use as proppants. In an alternate embodiment, refractory raw material is melted and then discretized into molten drops. The molten drops are cooled and frozen into generally spherical shapes. The cooled spheres are used as proppants.

Abstract: Hollow, porous, spherical metal-carbon composite particles, having nanostructures, are prepared from suitable precursor solutions containing metal-organic ligand coordination complexes with template. Such precursors may be made for each elemental metal to be in the spherical particles. The precursor solution is atomized as an aerosol in an inert gas stream and the aerosol stream heated to decompose the organic ligand portion of the precursor leaving the spherical metal-carbon composite or metal alloy-carbon composite particles. The organic ligand serves as a structure directing agent in the shaping of the spherical particles after the ligand has been removed. Other materials may also be used as permanent or removed templates. The morphology of the particles may be altered for an application by varying the preparation and composition of the metal precursor material, and the optional use of a template.

Abstract: A method for processing feed material to produce dense and spheroidal products is described. The feed material is comprised of powder particles from the spray-drying technique or solution precursor droplets from ceramic or metallic materials. The feed material is processed using plasma generated from a microwave. The microwave plasma torch employed is capable of generating laminar flow during processing which allows for the production of spheroidal particles with a homogenous materials distribution. This results in products having improved thermal properties, improved corrosion and wear resistance and a higher tolerance to interface stresses.

Abstract: Embodiments of the present disclosure provide for devices, methods for forming non-spherical particles, and the like.

Abstract: This disclosure relates to a method of preparing polyamide particles. The method include spray drying a solution containing a polyamide to form polyamide particles having an average diameter of between about 0.5 ?m and about 10 ?m and at least about 85% of the polyamide particles having a diameter distribution of no more than about 1.5 ?m.

Abstract: The present systems and methods utilize a polyamic acid solution as a precursor to form a polyimide bead having desired properties. The polyamic acid solution may be formed into a polyamic acid droplet. The polyamic acid droplet is then processed to form a polyamic acid bead, such as by extraction of solvent to concentrate the polyamic acid or by partial chemical imidization of the polyamic acid. The polyamic acid bead is then better able to retain its shape during subsequent processing steps, such as drying and pressurizing, before final thermal imidization.

Abstract: A method and formulation for preparing spray dried vancomycin. In various embodiment, the formulation includes vancomycin HC1 (10-20%) and one or more of the following PEG (0-5%), mannitol (0-5%), ethanol (0-10%), and a citrate buffer. Spray dried vancomycin has favorable reconstitution times and water content.

Abstract: An object of the present invention is to provide a freeze-dried aripiprazole powder formulation that exhibits good dispersibility and is easily dispersed into a homogenous suspension when reconstituted with water.