Formation Of Solid Particulate Material Directly From Molten Or Liquid Mass (e.g., Liquid Comminuting) Patents (Class 264/5)
  • Publication number: 20130119570
    Abstract: The present invention makes it possible to stably obtain uniform droplets and embolus particles in large quantities. Disclosed is a device for droplet formation which includes: a dispersed-phase outlet through which a dispersed-phase material, e.g., an aqueous gelatin solution, is discharged; continuous-phase outlets through which a continuous-phase material, e.g., an oil, is discharged; a confluence part which communicates with the dispersed-phase outlet and the continuous-phase outlets and in which the dispersed-phase material is caused to flow into the liquid of the continuous-phase material at a given constant static pressure; and a droplet formation part which has been disposed on the downstream side of the confluence part and in which the dispersed-phase material is allowed to become droplets by means of cohesive force.
    Type: Application
    Filed: May 16, 2011
    Publication date: May 16, 2013
    Inventors: Shinsuke Sugiura, Kenjiro Saomoto, Takashi Toyooka
  • Publication number: 20130116261
    Abstract: The present invention relates to nanoparticles for the encapsulation of compounds, the obtaining and uses thereof. The nanoparticles comprise a zein matrix and a basic amino acid. Said nanoparticles can encapsulate a water-soluble or fat-soluble biologically active compound. It is applicable in the food, pharmaceutical and cosmetic sectors and in the nanotechnology sector.
    Type: Application
    Filed: July 15, 2011
    Publication date: May 9, 2013
    Inventors: Maite Agüeros Bazo, Irene Esparza Catalán, Carolina González Ferrero, Carlos Javier González Navarro, Juan Manuel Irache Garreta, Ana Romo Hualde
  • Publication number: 20130109788
    Abstract: A spherical ? type crystal silicon carbide powder having an average particle diameter is of 5 ?m-60 ?m, specific pore volume of the inside pores in it having a diameter of 1 ?m or smaller is 0.02 cc/g or smaller, specific surface area of it is 1 m2/g or smaller, and average aspect ratio (short diameter/long diameter) of it is 0.65 or higher is proposed; a method for manufacturing the same including the steps of (1) spray-drying a slurry of a raw material silicon carbide powder which has an average particle diameter of 1 ?m or smaller and has an ? type crystal, to obtain porous and spherical particles, and (2) sintering the thus obtained porous and spherical particles, is also proposed.
    Type: Application
    Filed: October 31, 2012
    Publication date: May 2, 2013
    Inventor: Shinano Electric Refining CO., LTD.
  • Publication number: 20130106008
    Abstract: A method of preparing transparent or nontransparent silica aerogel granules. The method includes forming a granular wet gel by spraying a silica sol into alcohol, the silica sol being prepared by mixing a water glass solution or an opacifier-containing water glass solution with an inorganic acid solution, forming a granular alcohol gel through gelation aging and solvent substitution of the granular wet gel in alcohol, hydrophobically modifying the surface of the granular alcohol gel using an organic silane compound, and drying the surface modified gel at ambient pressure or in a vacuum. The method may prepare silica aerogel granules in a short period of time through heat treatment at a relatively low temperature and at ambient pressure or in a vacuum, thereby ensuring excellent economic feasibility, continuity and reliability, suited for mass production.
    Type: Application
    Filed: September 28, 2011
    Publication date: May 2, 2013
    Inventors: Young-Soo Ahn, Jeong-gu Yeo, Churl-Hee Cho
  • Patent number: 8425809
    Abstract: A method of forming granules, the method including forming a suspension of a nanopowder such as a nano zirconia powder containing yttria. The powder is formed from a suspension, and freon is added directly to the suspension as an additive. The suspension is then granulated by spray freeze drying, and the freon subsequently removed by heat treatment. The voids left by the vacated freon provide meso, micro and macro flaws or structural defects in the granules.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: April 23, 2013
    Assignee: Loughborough University
    Inventors: Annapoorani Ketharam, Balasubramaniam Vaidhyanathan, Bala Praveen Chakkravarthy Raghupathy, Jonathan Graham Peel Binner
  • Publication number: 20130091637
    Abstract: The invention relates to spray-dried, washfast dye compositions, preferably in the form of pigment powders, having a bleeding rate of ?0.5% and consisting of water-soluble functional dyes, preferably food dyes, which are firmly incorporated in a silica matrix. Apart from low bleeding of dye, these compositions are remarkable for their high stability to pH changes and/or ascorbic acid. The invention is also directed to the production of the dye compositions and the use thereof. The dye compositions are preferably employed in coloring foods, cosmetics, pharmaceutical products, but also in other uses.
    Type: Application
    Filed: June 2, 2010
    Publication date: April 18, 2013
    Applicant: Sensient Imaging Technologies GMBH
    Inventors: Volker Lischewski, Christoph Roth, Michael Felicetti, Katrin Schwager
  • Patent number: 8419971
    Abstract: A process for producing water-absorbing polymer particles by polymerizing droplets of a monomer solution in a gas phase surrounding the droplets, wherein the particle surface is coated at least partly with at least one polymer and/or wax.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: April 16, 2013
    Assignee: BASF SE
    Inventors: Uwe Stueven, Rüdiger Funk, Matthias Weismantel, Wilfried Heide, Marco Krüger
  • Publication number: 20130077731
    Abstract: A novel containment system for encapsulating nuclear fuel particles is disclosed. The containment system has a gas-impervious ceramic composite hollow shell having a spheroidal or ovoidal shape. The shell has a pair of longitudinally aligned round openings that are sealed with a gas-impervious ceramic composite tube to define a cavity between the shell inner surface and the tube outer surface. A ceramic composite matrix containing the nuclear fuel particles is enclosed within the cavity. The ceramic composite matrix has a controlled porosity, and can contain moderators or neutron absorbing material. The tube and shell are composed of a ceramic matrix composite material composed of ceramic reinforcement material that is bound together by a polymer-derived ceramic material.
    Type: Application
    Filed: March 28, 2012
    Publication date: March 28, 2013
    Applicant: TORXX Group Inc.
    Inventors: Walter J. Sherwood, Douglas Bruce Coyle
  • Patent number: 8388883
    Abstract: The use of induction furnaces for producing thermoelectric legs and components for thermoelectric modules is described, as is a process for producing thermoelectric semiconductor materials by co-melting mixtures of the particular element constituents of the thermoelectric semiconductor materials or alloys thereof in an induction furnace and pouring the melt thus obtained into the mold of a thermoelectric leg, or spraying the melt thus obtained to produce a pulverulent thermoelectric semiconductor material.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: March 5, 2013
    Assignee: BASF SE
    Inventors: Madalina Andreea Stefan, Michael Ditscher
  • Patent number: 8389013
    Abstract: A process for producing particles of a substance is described wherein a solution of the substance in a solvent is delivered in at least one shot into a supercritical fluid. The supercritical fluid is a non-solvent for the substance and is miscible with the solvent. Particles of the substance distributed in a mixture of the solvent and the supercritical fluid are formed.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: March 5, 2013
    Assignee: Newsouth Innovations PTY Limited
    Inventors: Neil Russell Foster, Roderick Peng Tze Sih
  • Patent number: 8377346
    Abstract: A process for the manufacture of a powder coating comprising the steps of: Preparing a powder coating premix comprising a resin and optionally a crosslinker therefor; Feeding the premix through a melt extruder; Cooling the extruded material; and Comminuting it to fine particles, wherein said process is characterized in that between 1 and 25 wt. % (based on the weight of said premix) of a process liquid is added to the melt extruder, wherein said process liquid is immiscible with at least said resin of the powder coating premix and wherein said process liquid evaporates when the premix leaves the extruder.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: February 19, 2013
    Assignee: Akzo Nobel Coatings International B.V.
    Inventors: Andrew Robert Morgan, Stephen Raymond Wilburn, Edward Clark
  • Patent number: 8372320
    Abstract: A method of producing dried cellulose nanofibrils includes atomizing an aqueous suspension of cellulose nanofibrils and introducing the atomized aqueous suspension into a drying chamber of a drying apparatus. The aqueous suspension is then dried, thereby forming substantially non-agglomerated dried cellulose nanofibrils.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: February 12, 2013
    Assignee: University of Maine System Board of Trustees
    Inventors: Douglas J. Gardner, Yousoo Han, Yucheng Peng
  • Publication number: 20130035345
    Abstract: The present invention relates to formulations and methods for increasing the bioavailability of 1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one, 1-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion.
    Type: Application
    Filed: March 7, 2012
    Publication date: February 7, 2013
    Applicant: Zalicus Pharmaceuticals Ltd.
    Inventors: Mahesh V. Padval, Jeff T. Gautschi, Daniel T. Smithey, Marshall D. Crew, Abizer Harianawala
  • Publication number: 20130030066
    Abstract: The invention relates to a polymer composition containing i) styrene polymer(s) and ii) phosphorylated polyether(s) with from 0.5 to 40% by weight phosphorus content, the main chain of which is formed exclusively from carbon atoms and from oxygen atoms, and which has at least three terminal and/or pendant OH groups, where these have been substituted with where ˜ indicates the bond to the polymer skeleton of the polyether; Y is O or S; t is 0 or 1; R1 and R2, being identical or different, are H, C1-C18-alkyl, C2-C18-alkenyl, C2-C18-alkynyl, C3-C10-cycloalkyl, C6-C10-aryl, furyl, C6-C10-aryl-C1-C10-alkyl, OR3, SR3, NR3R4, COR3, COOR3 or CONR3R4, or R1 and R2 form, together with the phosphorus atom P, a 4-8-membered ring system; R3 and R4, being identical or different, are H, C1-C16-alkyl, C2-C16-alkenyl, C3C16-alkynyl, C3-C10-cycloalkyl, C6-C10-aryl or C6-C10-aryl-C1-C10-alkyl, and/or polycarbonates containing phosphorus-containing group(s) of the general formula (I).
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Applicant: BASF SE
    Inventors: Klaus Hahn, Sabine Fuchs, Ingo Bellin, Patrick Spies, Maximilian Hofmann, Peter Deglmann, Klemens Massonne, Hartmut Denecke, Christoph Fleckenstein, Geert Janssens, Anna Müller-Cristadoro, Bernd Bruchmann
  • Patent number: 8361934
    Abstract: A method for fracture stimulation of a subterranean formation having a wellbore. The method comprise a series of steps. A slurry is injected into the wellbore at sufficiently high rates and pressures such that the formation fails and fractures to accept the slurry. The slurry comprises a fluid and a proppant, wherein said proppant comprises a styrene-ethylvinylbenzene-divinylbenzene terpolymer composition having a substantially cured polymer network, wherein said composition lacks rigid fillers or nanofillers. The proppant is emplaced within the fracture network in a packed mass or a partial monolayer of the proppant within the fracture, wherein the packed mass or partial monolayer props open the fracture; thereby allowing produced gases, fluids, or mixtures thereof, to flow towards the wellbore.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: January 29, 2013
    Assignee: Sun Drilling Products Corporation
    Inventor: Jozef Bicerano
  • Publication number: 20130012613
    Abstract: A method synthesizes a composition of polymers, copolymers, terpolymers and tetrapolymers. The composition may be made by combining in a reaction chamber, a crosslinking agent and one or more of a calix[n]arene, cyclodextrin, a mixture of a plurality of calix[n]arenes, different cyclodextrins, derivatives of calix[n]arenes, and derivatives of cyclodextrins, stirring the mixture, making a solid residue using microwaves, washing the solid residue, drying some of the wash, filtering some of the wash, and drying the resulting filtered solution. The composition may include alpha-cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin, the derivatives or corresponding mixtures thereof, and/or calix[n]arene(s) and/or of calix[n]arene derivative(s) and/or a mixture of two or more different calix[n]arenes selected from calix[n]arenes (n=4-20) and/or the derivatives thereof.
    Type: Application
    Filed: December 27, 2010
    Publication date: January 10, 2013
    Inventor: Mohamed Skiba
  • Publication number: 20130010914
    Abstract: Methods of forming composite bodies and materials including a metal oxide, such as, uranium dioxide, and silicon carbide are disclosed. The composite materials may be formed from a metal oxide powder, a silicon carbide powder and, optionally, a carbon powder. For example, the metal oxide powder, the silicon carbide powder and the carbon powder, if present, may each be combined with a binder and may be deposited in succession to form a precursor structure. Segments of the precursor structure may be removed and pressed together to form a multi-matrix material that includes interlaced regions of material including at least one of the metal oxide powder, the silicon carbide powder and, optionally, the carbon powder. The segments may be extruded or coextruded with another material, such as, a silicon carbide material, to form a green body. The green body may be sintered to form the composite bodies and materials having a desired final density.
    Type: Application
    Filed: July 8, 2011
    Publication date: January 10, 2013
    Inventors: John E. Garnier, Michael V. Glazoff, Sergey Rashkeev, George W. Griffith
  • Publication number: 20120322645
    Abstract: Nanocomposites of multi-phase metal oxide ceramics have been produced from water soluble salts of the resulting metal oxides by a foaming esterification sol-gel method. The evolution of volatile gases at elevated temperature during the esterification reaction causes the formation of a foam product. Nanocomposites of multi-phase metal oxide ceramics have also been produced by a cation polymer precursor method. In this second method, the metal cations are chelated by the polymer and the resulting product is gelled and foamed. Calcination of the resulting foams gives nanocomposite powders with extremely fine, uniform grains and phase domains. These microstructures are remarkably stable both under post-calcination heat treatment and during consolidation by hot-pressing.
    Type: Application
    Filed: December 16, 2011
    Publication date: December 20, 2012
    Inventors: Eric H. Jordan, Steven L. Suib, Aparna Iyer, Jacquelynn Garofano, Chun-Hu Chen
  • Publication number: 20120321896
    Abstract: The present invention provides particulate rasagiline mesylate having a particle size of about 255 microns to about 590 microns. Particularly it relates to a process of preparing rasagiline mesylate having large particle size by crystallisation techniques and devoid of comminution techniques to control particle size.
    Type: Application
    Filed: January 28, 2011
    Publication date: December 20, 2012
    Inventors: Kuppuswamy Nagarajan, Rajiv Kumar, Dharmesh Kumar Arvindbhai Patel, Jaman Mandaviya
  • Publication number: 20120321031
    Abstract: A new type of nuclear fuel rods. The rod cladding has an elliptical section transverse to its longitudinal direction and each nuclear fuel pellet has a truncated elliptical shape along the major axis of the cladding, the minor axis of the pellets is the same as the length of the minor axis of the cladding except for the assembly clearance j, the difference in length between the major axis of the cladding and the truncated major axis of the pellets is very much larger than the assembly clearance j. Also disclosed is a method of manufacturing nuclear fuel rods and stacking them in the cladding so as to form a nuclear fuel rod.
    Type: Application
    Filed: December 1, 2010
    Publication date: December 20, 2012
    Applicant: Commissariat A L'Energie Atomique Et Aux Energies Alternatives
    Inventor: Alain Ravenet
  • Publication number: 20120313269
    Abstract: A method and apparatus for producing metastable nanostructured materials employing a ceramic shroud surrounding a plasma flame having a steady state reaction zone into which an aerosol or liquid jet of solution precursor or powder material is fed, causing the material to be pyrolyzed, melted, or vaporized, followed by quenching to form a metastable nanosized powder that has an amorphous (short-range ordered), or metastable microsized powder that has a crystalline (long-range ordered) structure, respectively.
    Type: Application
    Filed: March 6, 2012
    Publication date: December 13, 2012
    Inventors: Bernard H. Kear, Vijay Shukla, Rajendra K. Sadangi
  • Patent number: 8329071
    Abstract: Multicomponent nanoparticles materials and apparatuses and processes therefor are disclosed. In one aspect of the disclosure, separate particles generated from solution or suspension or by flame synthesis or flame spray pyrolysis, and the resultant particles are mixed in chamber prior to collection or deposition. In another aspect of the disclosure, nanoparticles are synthesized in stagnation or Bunsen flames and allowed to deposit by thermophoresis on a moving substrate. These techniques are scalable allowing mass production of multicomponent nanoparticles materials and films. The foregoing techniques can be used to prepare composites and component devices comprising one or more lithium based particles intimately mixed with carbon particles.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: December 11, 2012
    Assignee: Hestia Tec, LLC
    Inventors: Hai Wang, Denis Phares
  • Publication number: 20120308499
    Abstract: The invention relates to a solid cosmetic composition, in the form of a loose or compact powder, comprising: (a) from 50% to 99% by weight of at least one particulate solid phase, (b) from 0.5% to 50% by weight of at least one non-volatile liquid phase, and (c) from 0.01% to 4% by weight of at least one block copolymer obtained from a first monomer of 2-acrylamidomethylpropanesulphonic acid and from a vinyl second monomer having a nitrogenous cyclic side chain. The invention also relates to a process for manufacturing such a composition, which comprises: (i) mixing the particulate solid phase, the non-volatile liquid phase, the block copolymer and water so as to obtain a slurry, (ii) suctioning off the water present in the slurry so as to obtain a dry powder.
    Type: Application
    Filed: August 31, 2011
    Publication date: December 6, 2012
    Applicant: LVMH RECHERCHE
    Inventors: Sabine VIC, Philippe FERRAND, Eric PERRIER
  • Patent number: 8313676
    Abstract: The present invention describes methods and tools for preparing a population of monodisperse polymer microparticles, which are of particular interest in the field of drug delivery.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: November 20, 2012
    Assignee: Koninklijke Philips Electronics N.V.
    Inventors: Marcel Rene Bohmer, Johannes Antonius Maria Steenbakkers, Suzanna Helena Petronella Maria De Winter
  • Patent number: 8313087
    Abstract: Described are powders for use in the production of three-dimensional structures or molded bodies by means of layered manufacturing methods, and methods for the economical production thereof. The powders have the particularity that they have a good flow behavior, on the one hand, and that they are simultaneously configured such that the molded body produced with the powder in rapid prototyping has substantially improved mechanical and/or thermal characteristics. In accordance with a particularly advantageous embodiment, the powder comprises a first fraction that is present in the form of substantially spherical powder particles and that is formed by a matrix material, and at least one further fraction in the form of strengthening and/or reinforcing fibers that are preferably embedded into the matrix material.
    Type: Grant
    Filed: March 21, 2005
    Date of Patent: November 20, 2012
    Assignee: EOS GmbH Electro Optical Systems
    Inventors: Peter Hesse, Tillmann Paul, Richard Weiss
  • Publication number: 20120286439
    Abstract: A particulate positive electrode material for lithium ion cells is prepared by dispersing manganese(II) sulfate, iron(II) sulfate, and lithium phosphate and/or lithium hydrogenphosphate in water to form a slurry, effecting hydrothermal reaction in an autoclave to synthesize a lithium compound: LiMnxFe1-xPO4 wherein x=0.05 to 0.5 as primary particles, preparing a dispersion comprising the primary particles and an organic substance, spraying the dispersion, granulating, and drying to form aggregated particles having an average particle size of 0.5-4 ?m, and firing the aggregated particles at 600-780° C. for carbonizing the organic substance therein, yielding secondary particles having a reduced carbon content.
    Type: Application
    Filed: May 2, 2012
    Publication date: November 15, 2012
    Inventors: Toshihiro Tsumori, Yasushi Takai
  • Publication number: 20120282468
    Abstract: A method for the preparation of an alkali metal cinnamate powdery product, preferably potassium cinnamate or sodium cinnamate, is disclosed herein. The resulting product has novel structural properties. The powder of the present disclosure is made via spray-drying and/or spray agglomeration and has a higher flowability, is less cohesive and less dusty, has an improved dissolution rate and in particular has a very favorable organoleptic profile. The disclosure is also directed to product applications in which the novel cinnamate product of the present disclosure may be applied.
    Type: Application
    Filed: December 2, 2010
    Publication date: November 8, 2012
    Applicant: Purac Biochem BV
    Inventors: Lambertus Hendricus Roozen, Elize Willem Bontenbal, Nikolaos Vogiatzis, Brenda Marja Dierdorp-Andreas
  • Patent number: 8298460
    Abstract: The invention relates to a method for granulating and crystallizing thermoplastic polymers, the granules being contained in a liquid after granulation of a polymer melt and the granules being nucleated in the liquid once the pressure of the liquid is increased and the temperature of the liquid is increased, and the granules being crystallized in the liquid once the pressure of the liquid is again increased and the temperature of the liquid is again increased. According to the invention, the granules are removed from the liquid once the pressure and the temperature of the liquid containing the granules have been reduced.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: October 30, 2012
    Assignee: Automatik Plastics Machinery GmbH
    Inventors: Andreas Doll, Frank Glöckner
  • Patent number: 8297959
    Abstract: Capsules and particles with at least one encapsulated and/or entrapped agent, such as therapeutic agent, imaging agents, and other constituents may be produced by electrohydrodynamic processes. More particularly, the agent encapsulated in a vehicle, capsule, particle, vector, or carrier may maximize treatment and/or imaging of malignant cancers while minimizing the adverse effects of treatment and/or imaging.
    Type: Grant
    Filed: May 2, 2007
    Date of Patent: October 30, 2012
    Assignee: Terapia Celular, LN, Inc.
    Inventors: Gustavo Larsen, Ruben Spretz, Raffet Velarde-Ortiz, David Vu, Luis Nunez
  • Publication number: 20120269729
    Abstract: A stabilized chitosan-based nanoparticle is provided having a chitosan polymer and a hydrophilic dispersing agent. In the stabilized nanoparticle, chains of the chitosan polymer electrostatically interact with chains of the hydrophilic dispersing agent to form an entangled network between the chitosan polymer and the hydrophilic dispersing agent. The stabilized chitosan-based nanoparticle has optimal particle integrity and stability properties under physiological conditions.
    Type: Application
    Filed: April 20, 2011
    Publication date: October 25, 2012
    Inventors: Swadeshmukul Santra, James Turkson, Astha Malhotra, Padmavathy Tallury
  • Publication number: 20120257707
    Abstract: A nuclear fuel includes a volume of a nuclear fuel material defined by a surface, the nuclear fuel material including a plurality of grains, some of the plurality of grains having a characteristic length along at least one dimension that is smaller than or equal to a selected distance, wherein the selected distance is suitable for maintaining adequate diffusion of a fission product from a grain interior to a grain boundary in some of the grains, the nuclear fuel material including a boundary network configured to transport the fission product from at least one grain boundary of some of the grains to the surface of the volume of the nuclear fuel material.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 11, 2012
    Inventors: Charles E. Ahlfeld, William W. Bowen, Roderick A. Hyde, Ronald L. Klueh, Sean M. McDeavitt, Joshua C. Walter, Steve R. Kirkendall
  • Publication number: 20120258150
    Abstract: Particles containing a polymer and a volatile material, such as a perfume, and particle gas saturated solution (PGSS) processes for making such particles are provided.
    Type: Application
    Filed: March 29, 2012
    Publication date: October 11, 2012
    Inventors: Holly Balasubramanian Rauckhorst, Vicenzo D'Acchioli, Andreas Josef Dreher
  • Publication number: 20120258366
    Abstract: A positive active material for a rechargeable lithium battery is a secondary particle formed of an assembly of primary particles of a nickel-based compound. The positive active material has an average particle diameter ranging from 5.5 ?m to 7.5 ?m and a specific surface area ranging from 0.40 m2/g to 2.0 m2/g. When the positive active material has an average particle diameter ranging from 11 ?m to 13 ?m, the positive active material has a specific surface area ranging from 0.15 m2/g to 1.0 m2/g. A rechargeable lithium battery includes the positive active material.
    Type: Application
    Filed: February 17, 2012
    Publication date: October 11, 2012
    Inventors: Dong-Hwan YU, Gun-Ho Kwak, Sung-Hoon Kim
  • Publication number: 20120252728
    Abstract: A method of treating functional dyspepsia and/or irritable bowel syndrome in mammals in need of treatment is disclosed herein. The method comprises administering to the mammal a formulation by inhalation, wherein the formulation avoids first pass metabolism of the active ingredient. The method comprises administering a formulation by pulmonary inhalation comprising a diketopiperazine and a glucagon-like peptide (GLP-1), analog, ROSE-010.
    Type: Application
    Filed: August 5, 2010
    Publication date: October 4, 2012
    Inventors: Peter Richardson, Enda Kenny, Per Hellstrom, Marshall L. Grant, Grayson W. Stowell, Scott Daniels, Anthony Smithson, Stephanie Greene
  • Publication number: 20120251595
    Abstract: The present invention relates to methods and compositions to prepare small size particles of poorly water soluble agents or drugs with surface enriched hydrophilicity.
    Type: Application
    Filed: November 9, 2010
    Publication date: October 4, 2012
    Inventors: Robert O. Williams, III, Keat Theng Chow
  • Publication number: 20120252297
    Abstract: Disclosed is a method of: providing a mixture of a polymer or a resin and a transition metal compound, producing a fiber from the mixture, and heating the fiber under conditions effective to form a carbon nanotube-containing carbonaceous fiber. The polymer or resin is an aromatic polymer or a precursor thereof and the mixture is a neat mixture or is combined with a solvent. Also disclosed are a carbonaceous fiber or carbonaceous nanofiber sheet having at least 15 wt. % carbon nanotubes, a fiber or nanofiber sheet having the a polymer or a resin and the transition metal compound, and a fiber or nanofiber sheet having an aromatic polymer and metal nanoparticles.
    Type: Application
    Filed: June 18, 2012
    Publication date: October 4, 2012
    Applicant: The Government of the United States of America as represented by the Secretary of the Navy
    Inventors: Teddy M. Keller, Matthew Laskoski
  • Publication number: 20120248640
    Abstract: Provided is by the present invention is a method for producing an EVOH resin having sufficient long-run workability in melt molding and enabling prevention of coloring such as yellowing, an EVOH resin obtained by this method for production, and a laminate obtained from this resin. The present invention is a method for producing an ethylene-vinyl alcohol copolymer resin, the method including a step of saponifying an ethylene-vinyl ester copolymer to obtain an ethylene-vinyl alcohol copolymer, in which the method is characterized by further including a step of irradiating the ethylene-vinyl ester copolymer or the ethylene-vinyl alcohol copolymer with an infrared ray.
    Type: Application
    Filed: March 30, 2011
    Publication date: October 4, 2012
    Applicant: KURARAY CO., LTD.
    Inventors: Toshio TSUBOI, Ray Jouett, Robert Armstrong, Yoshio Yamamoto
  • Patent number: 8268175
    Abstract: A method for transferring inorganic oxide nanoparticles from aqueous phase to organic phase. A modifier is used to change the surface polarity of inorganic oxide nanoparticles, followed by using proper solvents to transfer the modified inorganic oxide nanoparticles form aqueous phase to organic phase. The organic dispersion of modified inorganic oxide nanoparticles can be combined with a polymer to provide a polymer composite with the nanoparticles uniformly dispersed therein.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: September 18, 2012
    Assignee: Industrial Technology Research Institute
    Inventors: Guang-Way Jang, Yin-Ju Yang, Mei-Chih Hung, Hsiu-Yu Cheng, Jian-Yi Hang, Jen-Min Chen, Shu-Jiuan Huang
  • Publication number: 20120228788
    Abstract: A method for manufacturing a porous fuel comprising uranium, optionally plutonium and at least one minor actinide is provided. The method may comprise the following successive steps: a) a step for compacting as pellets a mixture of powders comprising uranium oxide, optionally plutonium oxide and at least one oxide of a minor actinide, at least one portion of the uranium oxide being in the form of triuranium octaoxide U3O8, the other portion being in the form of uranium dioxide UO2; b) a step for reducing at least one portion of the triuranium octaoxide U3O8 into uranium dioxide UO2.
    Type: Application
    Filed: September 1, 2010
    Publication date: September 13, 2012
    Applicant: Commissariat A' L'Energie Atomique et Aux Energies
    Inventors: Aurélien Jankowiak, Nathalie Herlet, Caroline Leorier, Nicolas Astier, Philippe Coste, Barbara Deschamps, Damien Prieur, Philippe Blanchart
  • Patent number: 8261577
    Abstract: There is provided a method for making hollow microspheres including heating a feed under conditions sufficient to convert at least a portion of the feed into hollow microspheres, where the heating is conducted under a vacuum. There is also provided hollow microspheres made using this method.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: September 11, 2012
    Assignee: 3M Innovative Properties Company
    Inventor: Gang Qi
  • Patent number: 8258083
    Abstract: A method for fracture stimulation of a subterranean formation includes providing a thermoset polymer nanocomposite particle precursor composition comprising a polymer precursor mixture, dispersed within a liquid medium, containing at least one of an initiator; at least one of a monomer, an oligomer or combinations thereof, said monomer and oligomer having three or more reactive functionalities capable of creating crosslinks between polymer chains; at least one of an impact modifier; and nanofiller particles substantially dispersed within the liquid medium; subjecting the nanocomposite particle precursor composition to suspension polymerizing conditions; subjecting the resulting nanocomposite particles to heat treatment; forming a slurry comprising a fluid and a proppant that includes the heat-treated nanocomposite particles; injecting the slurry into a wellbore; and emplacing the proppant within a fracture network in the formation.
    Type: Grant
    Filed: April 3, 2007
    Date of Patent: September 4, 2012
    Assignee: Sun Drilling Products Corporation
    Inventor: Jozef Bicerano
  • Publication number: 20120219695
    Abstract: Described is a process for producing pulverulent, antioxidant-comprising coating compositions, comprising providing an aqueous polymer dispersions comprising one or more antioxidants and a polymer obtained by radical polymerization of a) N,N-diethylaminoethyl methacrylate, and b) at least one radically polymerizable compound selected from esters of ?,?-ethylenically unsaturated mono- and dicarboxylic acids with C1-C8-alkanols, wherein the antioxidants are incorporated into the aqueous polymer dispersion in the form of a solution or of a dispersion, and spray processing the aqueous polymer dispersion to provide a powder form.
    Type: Application
    Filed: February 28, 2012
    Publication date: August 30, 2012
    Applicant: BASF SE
    Inventors: Karl Kolter, Maximilian Angel, Bernhard Linner
  • Publication number: 20120214885
    Abstract: In foamable polystyrene resin particles that are obtained by granulating a polystyrene resin containing a flame retardant and a foaming agent, the flame retardant has a bromine atom in a molecule, contains less than 70% by mass of bromine, has a benzene ring in a molecule, and has a 5% by mass decomposition temperature in a range of from 200° C. to 300° C., and a ratio (B/A) between (A) the amount of the flame retardant contained in the total foamable polystyrene resin particles and (B) the amount of the flame retardant contained in the surface of the resin particles is in a range of from 0.8 to 1.2. By pre-foaming the foamable polystyrene resin particles and then foaming the particles in a mold, a polystyrene resin foam-molded article having flame retardancy is obtained.
    Type: Application
    Filed: October 27, 2010
    Publication date: August 23, 2012
    Inventors: Hiroyuki Tarumoto, Ryosuke Chinomi
  • Publication number: 20120211909
    Abstract: Sulfur seeds may be produced by spraying liquid molten sulfur from a sulfur spray nozzle into a moving stream of liquid. Some of the sulfur may pass through the liquid and some of the sulfur may be entrained in and transported by the stream of liquid, or all of the sulfur may be entrained in the stream of liquid. The sulfur droplets that are entrained in the stream of liquid may be carried by the liquid to a cooling tank, which may be a spiral dewaterer tank with an angled bottom and a screw conveyor. An opening may be made in the bottom surface of the screw conveyor housing of the spiral dewaterer tank for liquid to drain from the screw conveyor as it moves sulfur seeds from the tank to a the drum. A screen may be disposed across the opening, and a drain trough attached to the screw conveyor housing to capture any liquid and solids that move through the screen. A wash line may assist in moving solids that pass through the screen.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 23, 2012
    Applicant: Brimrock International Inc.
    Inventors: Sergio A. De Paoli, Jamsheed P. Irani
  • Patent number: 8247527
    Abstract: A fine agglomerates mixture formed from pyrolysis of recyclable polymeric material such as scrap tires, polymeric automotive components, used rubber materials, and plastic containers. The mixture contains a carbon content ranged between about 80% to about 95% by weight of the fine agglomerates mixture. The fine agglomerates mixture has agglomerate particles averaging less than or equal to 35 nm. The fine agglomerates mixture also has a nitrogen surface area greater than or equal to 73 m2/g and includes an inorganic functional filler in a range between about 5% to about 20% weight of the fine agglomerates mixture.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: August 21, 2012
    Assignee: CBP Carbon Industries, Inc.
    Inventor: John H. Fader
  • Publication number: 20120207839
    Abstract: The present invention discloses a mineralized collagen/bioceramic composite useful as a hard tissue replacement material or substitute material, comprising about 10% to 95% by weight of mineralized collagen and about 5% to 90% by weight of bioceramics, and a method of manufacturing the same. Wherein, the mineralized collagen is used as a binder for the bioceramics, such as calcium phosphate ceramics, calcium sulfate ceramics, calcium carbonate ceramics, and other biocompatible ceramics. The bioceramic used in the mineralized collagen/bioceramic composite can be either in powder form or in granular form.
    Type: Application
    Filed: February 14, 2011
    Publication date: August 16, 2012
  • Patent number: 8237010
    Abstract: A therapeutic device for promoting the healing of a wound in a mammal is disclosed. An exemplary device comprises a permeable structure having a plurality of depressions formed in a surface thereof. In use, the surface having the depressions is disposed adjacent a surface of the wound. A method of manufacturing a therapeutic device for promoting the healing of a wound in a mammal comprising the steps of providing a permeable substrate, and forming a plurality of depressions into a surface of the permeable substrate to provide the therapeutic device. A method of treating a wound comprises: providing a permeable structure comprising a plurality of randomly disposed fibers and having i) a plurality of wound surface contact elements disposed between end portions of the structure, and ii) a plurality of voids defined by the contact elements; and applying the permeable structure to at least one surface of the wound.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: August 7, 2012
    Assignee: Boehringer Technologies, L.P.
    Inventors: John R. Boehringer, John Karpowicz, Christopher L. Radl
  • Publication number: 20120195965
    Abstract: The invention provides stable, solid dosage forms and pharmaceutical compositions in particulate form comprising a fibrate, for example fenofibrate, dissolved in an non-aqueous vehicle in order to ensure improved bioavailability of the active ingredient upon oral administration relative to known fibrate formulations.
    Type: Application
    Filed: December 8, 2011
    Publication date: August 2, 2012
    Applicant: Veloxis Pharmaceuticals A/S
    Inventors: Per HOLM, Tomas NORLING
  • Publication number: 20120187591
    Abstract: The present invention provides for methods of preparing silk nanoparticles and microparticles, methods of encapsulating an active agent into the silk nano- and microparticles and compositions comprising these silk particles. In particular, the silk spheres are prepared from phase separation of silk and polyvinyl alcohol (PVA), without exposure to an organic solvent. The method employs a chemical, PVA, which is an FDA-approved ingredient in drug formulations. Different parameters can be adjusted to control the size and shape of the silk spheres during the fabrication process. The silk particle compositions of the present invention may also encapsulate active agents or chemicals. Such compositions allow the active agents to be controllably and sustainably released to the target organs or tissues. The silk composition entrapping active agents also provides for a long-term storage medium for the active agents so entrapped.
    Type: Application
    Filed: September 29, 2010
    Publication date: July 26, 2012
    Inventors: Xiaoqin Wang, David L. Kaplan
  • Publication number: 20120183116
    Abstract: A composite nuclear fuel pellet comprises a composite body including a UO2 matrix and a plurality of high aspect ratio particies dispersed therein, where the high aspect ratio particies have a thermal conductivity higher than that of the UO2 matrix. A method of making a composite nuclear fuel pellet includes combining UO2 powder with a predetermined amount of high aspect ratio particles to form a combined powder, the high aspect ratio particles having a thermal conductivity higher than that of the UO2 powder; mixing the combined powder in a solvent to disperse the high aspect ratio particles in the UO2 powder; evaporating the solvent to form a dry mixture comprising the high aspect ratio particles dispersed in the UO2 powder; pressing the dry mixture to form a green body; and sintering the green body to form the composite fuel pellet.
    Type: Application
    Filed: July 27, 2010
    Publication date: July 19, 2012
    Inventors: Daniel F. Hollenbach, Larry J. Ott, James W. Klett, Theodore M. Besmann, Beth L. Armstrong