Including Eye Photography Patents (Class 351/206)
  • Patent number: 11653830
    Abstract: A multi-view diagnostic system includes an OCT engine and a plurality of optical elements defining a plurality of beam paths between the OCT engine and an ophthalmic target, with each beam path corresponding to a different viewing angle of the ophthalmic target. The system also includes a scanner to direct OCT imaging beams generated by the OCT engine toward the ophthalmic target along each respective beam path. Instructions stored in memory are executable by a processor to determine a characteristic of the ophthalmic target based on OCT light reflected by the ophthalmic target along each respective beam path and detected by the OCT engine.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: May 23, 2023
    Assignee: Alcon Inc.
    Inventors: Martin Gründig, Peter Zieger
  • Patent number: 11627874
    Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: April 18, 2023
    Assignee: ACUCELA INC.
    Inventors: Lukas Scheibler, Matthias Pfister, Urban Schnell, Stefan Troller, Ryo Kubota
  • Patent number: 11596302
    Abstract: Disclosed is an eye examination apparatus for use with a smartphone. The eye examination apparatus has a body having a first eye opening and a second eye opening for a user to see into the eye examination apparatus using two eyes. In accordance with an embodiment of the disclosure, the eye examination apparatus has a coupling for receiving a smartphone having a display and a camera and for holding the smartphone in a predefined position in relation to the body, such that the camera of the smartphone is positioned to acquire ophthalmic images through the first eye opening, and the display of the smartphone is viewable through the second eye opening. In this manner, it is possible for the user to have an eye examination performed remotely outside of a clinician's office without specialized equipment by instead using their own smartphone.
    Type: Grant
    Filed: May 10, 2022
    Date of Patent: March 7, 2023
    Assignee: Neuroptek Corporation Inc.
    Inventors: Behzad Mansouri, Neda Anssari
  • Patent number: 11589745
    Abstract: Embodiments of the invention include a method to determine a binocular alignment, the method comprising: measuring a disassociated phoria of a first eye and a second eye of a patient at an apparent distance; and determining an accommodative convergence of the first eye and the second eye at the apparent distance using the measured disassociated phoria. In other embodiments, a system to determine a binocular alignment comprises a stereo display, for a projection of images for a first eye and a second eye; an accommodation optics, to modify the projection of the images according to an apparent distance; an eye tracker, to track an orientation of the first eye and the second eye; and a computer, coupled to the stereo display, the accommodation optics and the eye tracker, to manage a determination of the binocular alignment.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: February 28, 2023
    Assignee: Neurolens, Inc.
    Inventors: Jeffrey P. Krall, Aric Plumley
  • Patent number: 11583179
    Abstract: Sensor data is captured with a sensor. The sensor data includes a lens-position of a prescription lens relative to a reference point of an optical coherence tomography (OCT) system. A mirror of a reference arm of the OCT system is positioned at an optical pathlength between an eye region of the prescription lens based at least in part on the sensor data. An OCT signal is generated while the mirror is positioned at the optical pathlength. At least one depth profile is generated that includes the prescription lens and the eye region.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: February 21, 2023
    Assignee: Meta Platforms Technologies, LLC
    Inventors: Ruobing Qian, Mohamed Tarek El-Haddad, Robin Sharma
  • Patent number: 11571123
    Abstract: An ophthalmologic processing apparatus according to embodiments acquires data of a fundus of a subject's eye optically. The ophthalmologic apparatus includes a fixation system, an image acquisition unit, a specifying unit, and a determination unit. The fixation system is configured to project fixation light onto an eye of a subject. The image acquisition unit is configured to acquire an image of the fundus of the subject's eye in a state where the fixation light is projected by the fixation system. The specifying unit is configured to analyze the image acquired by the image acquisition unit to specify an image region corresponding to a predetermined site of the fundus. The determination unit is configured to determine whether or not the image region specified by the specifying unit is included within a predetermined range in the image acquired by the image acquisition unit.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: February 7, 2023
    Inventor: Yusuke Ono
  • Patent number: 11564568
    Abstract: An eye imaging system can include a head-wearable fundus camera positioning helmet with an outer shell and a conformable liner that can include head location fiducials defining a specified plane. An attached articulating fundus camera fixture can include a fundus camera positioning indication system to indicate a position of the fundus camera with respect to an eye of the patient for acquiring one or more fundus camera images at the indicated position such that fundus camera images recorded over a chronic period of time are assessable using the position information from the fundus camera positioning indication system. The articulating fundus camera fixture can include an articulating arm and a fundus camera mount. The system can assist the patient with helmet positioning, and can automatically position the fundus camera for accurate image capture and analysis, such as using a trained machine learning model for patient evaluation, monitoring, or diagnosis.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: January 31, 2023
    Assignee: Agnya Perceptive Solutions, L.L.C.
    Inventors: Sanjiv Bhatt, Saurin Shah, Dmitriy Yam
  • Patent number: 11559202
    Abstract: System for integrally measuring clinical parameters of the visual function including a display unit (20) for representing a scene with a 3D object having variable characteristics such as virtual position and virtual volume of the 3D object within the scene; movement sensors (60) for detecting the user head position and distance from the display unit (20); tracking sensors (10) for detecting the user pupils position and pupillary distance; an interface (30) for the user interaction on the scene; processing means (42,44) for analysing the user response based on the data coming from sensors (60,10) and the interface (30), with the characteristics variations of the 3D object; and based on the estimation of a plurality of clinical parameters of the visual function related to binocularity, accommodation, ocular motility and visual perception.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: January 24, 2023
    Inventor: Eva Garćia Ramos
  • Patent number: 11557020
    Abstract: An eye tracking system for tracking one or more of a user's eyes includes an closed-eye detector operable to detect when a user has closed one or more of their eyes, an eye tracker operable to detect an eye orientation in dependence upon a measured deformation of an eyelid corresponding to the an eye that has been detected to be shut, and an image renderer operable to render a foveated image for display in response to the detected eye orientation.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: January 17, 2023
    Assignee: Sony Interactive Entertainment Inc.
    Inventor: Patrick John Connor
  • Patent number: 11547293
    Abstract: A method of processing a sequence of images of a retina acquired by an ophthalmic device to generate retinal position tracking information indicative of retina movement during acquisition. The method includes (i) receiving one or more images of the retina; (ii) calculating a cross-correlation between a reference image and an image based on the received image(s) to acquire an offset between the image and reference image; and repeating processes (i) and (ii) to acquire, as the tracking information, respective offsets for images that are based on the respective received image(s). Another step includes modifying the reference image during the repeating, by determining a measure of similarity between correspondingly located regions of pixels in two or more received images and accentuating features in the reference image representing structures of the imaged retina in relation to other features in the reference image based on the determined measure of similarity.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: January 10, 2023
    Assignee: OPTOS PLC
    Inventor: David Clifton
  • Patent number: 11523735
    Abstract: A headrest for an ophthalmic instrument facilitates fine positioning of the instrument relative to an eye of a test subject without the need to remove a contact element of the headrest from contact with the test subject's face. The ophthalmic instrument may be, for example, a rebound tonometer or a non-contact tonometer. The headrest includes a hollow bulbous contact element formed of resiliently deformable material, for example a thermoplastic elastomer (TPE) or silicone rubber. An outer surface of the contact element may have a spherical shape or a spheroidal shape when the contact element is not deformed.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: December 13, 2022
    Assignee: Reichert, Inc.
    Inventors: Russell J. Bonaventura, James M. Schweitzer
  • Patent number: 11518408
    Abstract: A driver monitor system and method for predicting impairment of a user of a vehicle. The system includes video cameras, an input device for inputting a list of medications being taken by the driver. Processing circuitry predicts side effects of the medications based on the half-life of the medication, detecting eye gaze movement, eye lid position, and facial expression of the user using images from the video camera, predicting whether the user is transitioning into an impaired physical state that is a side effect of the medications, verifying the side effect of the medications, determining whether the user is fit to drive using the verified side effects of the medications, and outputting to the vehicle an instruction to operate the vehicle in a level of automation that makes up for the at least one side effect or to perform a safe pull over operation of the vehicle.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: December 6, 2022
    Inventors: Nikos Arechiga-Gonzalez, Soonho Kong, Jonathan Decastro, Frank Permenter, Dennis Park
  • Patent number: 11510568
    Abstract: A fundus imaging apparatus includes an imaging optical system that irradiates a fundus of a subject eye with light through an objective lens system, and enables to capture a fundus image of the subject eye based on return light from the subject eye, and a diopter correction unit that includes an optical element disposed on an optical path of the imaging optical system and a drive unit driving the optical element, and performs a diopter correction with a diopter value corresponding to a drive amount of the optical element. A drive range of the optical element in the diopter correction unit is set to avoid a specific range being a range in which an artifact caused by reflection light in the objective lens system is maximized.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: November 29, 2022
    Assignee: NIDEK CO., LTD.
    Inventors: Shinya Iwata, Megumi Tsuchiya, Yukihiro Higuchi
  • Patent number: 11510567
    Abstract: In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's/subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and/or structural ophthalmic tests and output the test data.
    Type: Grant
    Filed: September 14, 2021
    Date of Patent: November 29, 2022
    Assignee: Doheny Eye Institute
    Inventors: Alexander C. Walsh, Paul G. Updike, Srinivas R. Sadda
  • Patent number: 11503996
    Abstract: The object of the present invention is to develop an ophthalmologic microscope of a new method that increases the degree of freedom in the optical design in the Galilean ophthalmologic microscope provided with an OCT optical system. The present invention provides an ophthalmologic microscope 1 comprising; an illuminating optical system 300, an observation optical system 400; an objective lens 2; and an OCT optical system 500, characterized in that the optical axis O-500 of the OCT optical system does not penetrate through the objective lens 2, it comprises objective lens for OCT 507 through which the optical axis O-500 of the OCT optical system penetrates, and deflection optical elements 503a, 503b for scanning of the OCT optical system and the objective lens for OCT 507 are in a substantially optically conjugate positional relation.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: November 22, 2022
    Assignee: Topcon Corporation
    Inventors: Yasufumi Fukuma, Kazuhiro Oomori
  • Patent number: 11490805
    Abstract: A new technique is provided to easily grasp the form of the fundus and the like of the eye to be examined being depicted in a tomographic image. An ophthalmic information processing device includes an image rotation circuit and a display control circuit. The image rotation circuit rotates a tomographic image of the eye to be examined acquired by using optical coherence tomography while making a measurement optical axis be eccentric relative to a predetermined site of the eye to be examined, in accordance with an eccentric amount and an eccentric direction of the measurement optical axis relative to the predetermined site. The display control circuit causes a display device to display the tomographic image rotated by the image rotation circuit.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: November 8, 2022
    Inventors: Ryoichi Hirose, Tatsuo Yamaguchi
  • Patent number: 11471049
    Abstract: An ophthalmologic apparatus comprises eye information obtaining portions, each of the eye information obtaining portions corresponding to each of subject eyes of a subject and configured to obtain information on each of the subject eyes; imaging portions, each of the imaging portions corresponding to each of the eye information obtaining portions and configured to capture a subject eye image of each of the subject eyes; a reference calculator configured to obtain a three-dimensional reference position in each of the subject eye images captured by each of the imaging portions; an inclination calculator configured to obtain inclination information indicating inclination of relative positions of the subject eyes from the obtained three-dimensional reference positions in the subject eye images; and a notification portion configured to notify the obtained inclination information.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: October 18, 2022
    Inventors: Takafumi Yukimori, Shigeru Okikawa
  • Patent number: 11464407
    Abstract: A method for generating an indicator or biomarker of colour perception in a mammalian subject, where the method may include submitting the mammalian subject to a multicoloured dynamic stimulus comprising displaying, on a display device. The method may include controlling a change over time of at least one of the two colours of the multicolour pattern when displaying the dynamic multicolour stimulus, to vary the displayed luminance of this colour (usually several times). The method may include acquiring, by using an image acquisition device, an oscillatory response of a pupil of the mammalian subject. The method may include generating, from the acquired response, a signal representative of the power of the pupil's oscillatory response as a function of the change over time of at least one of the two colours when displaying the dynamic multicoloured stimulus.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: October 11, 2022
    Inventors: Pierre Pouget, Alexis Genin
  • Patent number: 11452442
    Abstract: Disclosed are systems and methods for generating wide-field optical coherence tomography angiography (OCTA) images. In embodiments, multiple OCTA scans of a sample are automatically acquired at overlapping locations. The systems and methods include functionality to adaptively control the scanning procedure such that eye blink and eye motion events are detected in real time and accounted for during 3D scan acquisition. Also disclosed are methods for detecting and correcting motion-related artifacts in OCTA datasets which allow for the longer scan times over larger fields of view required for wide-field imaging. These methods may include division of en face angiogram images into a set of motion-free parallel strips, and application of gross and fine registration methods to align overlapping strips into a motion-corrected composite image. A series of overlapping motion-corrected composite images may be combined into a larger montage to enable wide-field OCTA imaging using multiple OCTA scans.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: September 27, 2022
    Inventors: David Huang, Gangjun Liu, Yali Jia
  • Patent number: 11422094
    Abstract: The analysis of data from fluorescence microscopy is disclosed, more especially fluorescence fluctuation microscopy, being a correlation analysis of fluctuation of the fluorescence intensity enabling quantitative and dynamic information capture. In particular the analysis is described of characteristics such as concentrations, mobility, interactions, stoichiometry, etc. of mixtures of particular that are fluorescently labeled with differently colored fluorophores having different excitation/emission spectra using fluctuation microscopy.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: August 23, 2022
    Assignees: Universiteit Hasselt, Ludwig-Maximilians-Universität München
    Inventors: Jelle Hendrix, Nick Smisdom, Don Lamb, Waldemar Schrimpf
  • Patent number: 11421979
    Abstract: The invention relates to a method for creating a two-dimensional interferogram with a Michelson-type free-beam interferometer, comprising an extended, partially spatially coherent light source and a two-dimensional light detector, wherein light from the light source is split by a beam splitter with a semitransparent beam splitter mirror into a sample light beam and a reference light beam and taken to a sample arm and a reference arm, wherein the sample light beam returning from a sample is directed by the beam splitter mirror onto the light detector, wherein the reference light beam emerging from the reference arm makes a predetermined angle greater than zero with the sample light beam on the light detector, and wherein the length of the reference arm is variable, where the reference light beam is directed by means of an odd number of reflections in each reflection plane in at least one reference arm section so that it is displaced laterally to itself and travels antiparallel through a light-deflecting elemen
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: August 23, 2022
    Assignee: VISOTEC GMBH
    Inventors: Michael Münst, Helge Sudkamp, Peter Koch, Gereon Hüttmann
  • Patent number: 11412926
    Abstract: A mobile communication device-based corneal topography system includes an illumination system, a mobile communication device and a corneal topography optical housing. The illumination system is configured to generate an illumination pattern and to generate reflections of the illumination pattern off a cornea of a subject, wherein the illumination system is aligned along an axis of centers of the illumination pattern. The mobile communication device includes an image sensor to capture an image of the reflected illumination pattern. The corneal topography optical housing is coupled to the illumination system and the mobile communication device, wherein the corneal topography optical housing supports and aligns the illumination system with the image sensor of the mobile communication device. The corneal topography optical housing includes an imaging system coupled to the image sensor.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: August 16, 2022
    Assignee: Intelligent Diagnostics, LLC
    Inventors: David A. Wallace, Stephen Klyce, John R Rogers, R Stephen Mulder, Mark A Kahan, Paul E Glenn
  • Patent number: 11406262
    Abstract: A device, system, and method for operating a nystagmus testing device is disclosed. The device comprising a camera configured to face a test subject to capture eye movements of the test subject, a start button configured to start a nystagmus routine, a front display positioned to face the test subject configured to display a visual stimulus, a rear display positioned to face a test administrator configured to display a visual tracker, and a controller configured to control movements of the visual stimulus and the visual tracker on the front and rear display, respectively, and generate data of the nystagmus routine.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: August 9, 2022
    Inventor: Peter F. Zahrt
  • Patent number: 11393251
    Abstract: A method for detecting one or more gaze-related parameters of a user is disclosed. In one example, the method includes creating a left image of at least a portion of a left eye of the user using a first camera of a head-wearable device worn by the user, and creating a right image of at least a portion of a right eye of the user using a second camera of the head-wearable device. The left and right images are fed together as an input into a convolutional neural network. One or more gaze-related parameters are obtained from the convolutional neural network as a result of the left and right images input.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: July 19, 2022
    Assignee: Pupil Labs GmbH
    Inventors: Marc Tonsen, Kai Dierkes, Moritz Kassner, Bernhard Petersch
  • Patent number: 11394896
    Abstract: Provided is a method for obtaining an image includes: obtaining first image data by photographing a first color by means of the image sensor while an IR illumination is turned on; obtaining second image data by photographing the first color by means of the image sensor while an IR illumination is turned off; extracting, from the first image data, first row data obtained from a first pixel of the image sensor; extracting, from the first image data, IR row data corresponding to an IR component of the first pixel; and generating correction data of the first pixel based on a difference between the first row data and the IR row data. According to an embodiment, the artificial intelligence (AI) module may be related to unmanned aerial vehicles (UAVs), robots, augmented reality (AR) devices, virtual reality (VR) devices, and 5G service-related devices.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: July 19, 2022
    Inventors: Jaehyun An, Jiwon Lee
  • Patent number: 11382503
    Abstract: The present invention is an OCT imaging system user interface for efficiently providing relevant image displays to the user. These displays are used during image acquisition to align patients and verify acquisition image quality. During image analysis, these displays indicate positional relationships between displayed data images, automatically display suspicious analysis, automatically display diagnostic data, simultaneously display similar data from multiple visits, improve access to archived data, and provide other improvements for efficient data presentation of relevant information.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: July 12, 2022
    Inventors: Jochen Straub, Shahram Shawn Dastmalchi
  • Patent number: 11375892
    Abstract: An exemplary aspect is a method of processing data acquired by applying an optical coherence tomography (OCT) scan to a sample. The method includes preparing a three dimensional data set acquired from a sample, creating a two dimensional map based on representative intensity values of a plurality of pieces of A-scan data included in the three dimensional data set, placing the three dimensional data set based on the two dimensional map, and executing a process based on at least a partial data set of the three dimensional data set on which placement based on the two dimensional map has been performed.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: July 5, 2022
    Inventors: Hisashi Tsukada, Atsushi Kubota, Yasufumi Fukuma
  • Patent number: 11363947
    Abstract: An optical coherence tomographic device configured to acquire a tomographic image of a subjected eye is disclosed herein. The optical coherence tomographic device may include a light source of wavelength sweeping type; and a measurement optical system configured to irradiate the subjected eye with light outputted from the light source, where D/S×?>1.61 may be satisfied, with a diameter of the light outputted from the light source at an incident position to the subjected eye is D, a wavelength swept frequency of the light source is S, and a center wavelength of the light outputted from the light source is ?.
    Type: Grant
    Filed: January 20, 2021
    Date of Patent: June 21, 2022
    Inventors: Yuji Nozawa, Chihiro Kato, Takashi Kamo
  • Patent number: 11350820
    Abstract: The technology described in this document can be embodied in systems and computer-implemented methods for determining a score representing an amount of staining of the cornea. The methods include obtaining a digital image of the cornea stained with a tracer material, receiving a selection of a portion of the image, and processing, by a processing device, the selection to exclude areas with one or more artifacts to define an evaluation area. For each of a plurality of pixels within the evaluation area, a plurality of Cartesian color components are determined and a hue value in a polar coordinate based color space is calculated from the components. An amount of staining of the cornea is then determined as a function of the hue value. The methods also include assigning a score to the evaluation area based on the amount of staining calculated for the plurality of pixels.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: June 7, 2022
    Assignee: Massachusetts Eye and Ear Infirmary
    Inventors: Reza Dana, Francisco L. Amparo Pulido, Haobing Wang
  • Patent number: 11347052
    Abstract: There is provided a display control apparatus capable of displaying a high-quality image while inhibiting a load at the time of displaying the image in front of a user. There is provided a display control apparatus including a signal processing unit that performs signal processing in which a first mode and a second mode are switchable at a first region in a screen and a region other than the first region in the screen, display being performed at a first resolution in the first mode, display being performed at a second resolution in the second mode, in which the signal processing unit performs display while reducing a resolution in the second mode toward an outer periphery of the screen.
    Type: Grant
    Filed: September 3, 2018
    Date of Patent: May 31, 2022
    Inventor: Yusuke Onoyama
  • Patent number: 11337604
    Abstract: A method to image an in vivo object in an eye includes illuminating an object in the eye by a light source; configuring one or more detectors to receive light from a conjugate plane behind a confocal plane of the object, the conjugate plane acting as a light screen; receiving at the one or more detectors a backscattered light from the light source which has been refracted at least in part by the object before being backscattered from the light screen to provide a detector data; and processing the detector data over a time period by a computer to generate information about the object.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: May 24, 2022
    Assignee: University of Rochester
    Inventors: Raul Andres Guevara-Torres, Jesse Schallek, Aby Joseph
  • Patent number: 11337607
    Abstract: An ophthalmic imaging apparatus comprising: an illumination light source and an optical assembly for directing light from the light source into an eye of a subject; a photosensor array comprising a plurality of photosensors positioned for acquiring images of portions of a fundus of the eye; an objective lens positioned along an imaging axis intersecting a point on the fundus of the eye wherein the objective lens is positioned for refracting light that has been reflected by the fundus to form an image of the fund us on an image plane of the objective lens such that the image plane is positioned away from the photosensor array; and a microlens array comprising a plurality of microlenses wherein the microlens array is spaced away from and positioned behind the image plane and wherein the microlens array is positioned in between the image plane and the photosensor array such that each microlens in the array projects a different view of the image formed at the image plane thereby forming an array of elemental imag
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: May 24, 2022
    Assignee: Integral Scopes Pty Ltd.
    Inventors: Anjali Jaiprakash, Douglas Palmer, Donald Gilbert Dansereau, Thomas Coppin, Krishan Rana, Jonathan Roberts, Ross Crawford
  • Patent number: 11333901
    Abstract: Disclosed is a method for determining the position of the eye rotation center of a subject's eye including: providing a geometric model of an eye, the eye being modeled with one sphere for the sclera and one ellipsoid for the cornea of the eye, the position of the eye rotation center being the distance between a center of the sclera and an apex of the cornea and being determined based on a set of personal parameters including a first geometric dimension of the eye, each personal parameter distinct from the position of the eye rotation center; determining a value of each personal parameter; and determining a first approximate value of eye position rotation center based on the geometric model using the personal parameters. Also disclosed is a method for calculating a personalized ophthalmic lens for the eye using such center, as well as a device implementing this method.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: May 17, 2022
    Assignee: Essilor International
    Inventor: Didier Grand-Clement
  • Patent number: 11324398
    Abstract: A method is provided for observing structure and function of individual cells in a living human eye, comprising: using an adaptive optics optical coherence tomography (AO-OCT) system to image a volume of a retinal patch including numerous cells of different types, as for example, ganglion cells; using 3D subcellular image registration to correct for eye motion, including digitally dissecting the imaged volume; and using organelle motility inside the cell to increase cell contrast and to measure cell temporal dynamics.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: May 10, 2022
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Donald Thomas Miller, Zhuolin Liu, Kazuhiro Suzuki, Furu Zhang
  • Patent number: 11307330
    Abstract: A variable focal length optical system includes: an imaging lens configured to condense a parallel beam of light from an objective lens to form an intermediate image; a relay system including, in sequence from an object side, a first relay lens and a second relay lens and configured to relay the intermediate image to infinity; and a lens system of a liquid resonant type which is located between the first relay lens and the second relay lens. A front principal point of the lens system is located to be conjugated with an exit pupil of the objective lens and an expression, 1.90?fTube/fR1?2.15, is satisfied. In the expression, fTube denotes a focal length of the imaging lens and fR1 denote a focal length of the first relay lens.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: April 19, 2022
    Inventors: Koji Kubo, Yuko Shishido
  • Patent number: 11298019
    Abstract: An ophthalmologic apparatus includes an acquisition unit and a controller. The acquisition unit includes an optical scanner capable of deflecting light in a predetermined deflection angle range. The acquisition unit is configured to acquire data of a subject's eye by performing A-scan on the subject's eye using optical coherence tomography by measurement light deflected by the optical scanner. The controller is configured to cause the acquisition unit to perform A-scan based on a deflection operation state of the optical scanner.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: April 12, 2022
    Inventors: Ryoichi Hirose, Tatsuo Yamaguchi
  • Patent number: 11291363
    Abstract: An automatic strabismus detection mechanism includes a housing and an eyepiece arranged on the housing. A lens mechanism located on a same axis as the eyepiece is arranged in the housing. The lens mechanism is provided with a rotating mechanism for adjusting an angle of refraction. The automatic strabismus detection mechanism includes technical effects of being composed of the lens mechanism and automatically controlled to generate 0 to 50 prism degrees; the volume is small and the weight is light, which is lighter than that of a triangular prism block made of ordinary glass; and the manufacturing cost is low, which is about one fifth of the price of a lens row. Therefore, with the automatic strabismus detection mechanism, a variety of equipment and instruments based on the principle of triangular prism spectroscopic detection or dispersion is greatly improved, and development of related instruments and equipment is facilitated.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: April 5, 2022
    Inventor: Dongguang Liu
  • Patent number: 11295128
    Abstract: An example embodiment includes: a determination unit that, based on an image including an eye of a recognition subject, determines whether or not a colored contact lens is worn; and a matching unit that, when it is determined by the determination unit that the colored contact lens is worn, performs matching of the iris by using a feature amount extracted from a region excluding a predetermined range including an outer circumference of the iris out of a region of the iris included in the image.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: April 5, 2022
    Inventors: Mamoru Inoue, Jinit Bhatt
  • Patent number: 11294174
    Abstract: The present application provides a virtual image display apparatus. The virtual image display apparatus includes an image source configured to produce imaging illumination; an optical relay configured to receive the imaging illumination from the image source, and configured to transmit a detection light having an aberrated wavefront representing imaging distortion in a virtual image displayed by the virtual image display apparatus; a wavefront sensor configured to receive the detection light, and configured to detect wavefront aberration information from the detection light; and a wavefront correction processor configured to receive the wavefront aberration information from the wavefront sensor, and configured to adjust in real time the imaging illumination produced by the image source to reduce the imaging distortion in real time.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: April 5, 2022
    Assignee: BOE Technology Group Co., Ltd.
    Inventor: Yanjun Chen
  • Patent number: 11283975
    Abstract: An imaging device includes a housing having a surface that can engage the face of a patient. A cavity is at least partially defined by the surface. An anterior imaging system includes an optical lens barrel positioned inside the cavity, and the optical lens barrel includes a variable focus lens at one end and an image sensor array at an opposite end. One or more illumination LEDs are positioned around the periphery of the optical lens barrel at opposite sides of the variable focus lens, and are configured to illuminate the cavity to capture images of an anterior of the eye.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: March 22, 2022
    Assignee: Welch Allyn, Inc.
    Inventors: Thomas A. Myers, Christian H. Reinke, Carlos A. Suarez, Ynjiun P. Wang
  • Patent number: 11259700
    Abstract: Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: March 1, 2022
    Assignee: TearScience Inc
    Inventors: Donald R. Korb, William L. Weber, Randal B. Chinnock, Benjamin T. Gravely, Stephen M. Grenon
  • Patent number: 11262184
    Abstract: An optical coherence tomography (OCT) system for profilometry measurements of a specimen with a lateral resolution across the profilometry measurements is provided. The OCT system includes a line-field generator, an interferometer, and a spectrometer. The line-field generator includes a filter arranged in a focal plane of a lens for spatially filtering extended line-field light into a line-field light of a width equal to the lateral resolution. The interferometer is configured to interfere the line-field light reflected from the specimen illuminated with a line-shaped focus with a reference signal of the line-field light to produce an interference pattern. The spectrometer configured to analyze spectral components of the interference pattern in a digital domain to produce the profilometry measurements of the specimen.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: March 1, 2022
    Assignee: Mitsubishi Electric Research Laboratories, Inc.
    Inventors: David Millar, Celalettin Yurdakul, Pu Wang, Kieran Parsons
  • Patent number: 11253151
    Abstract: A multispectral or hyperspectral ocular surface evaluating device is disclosed, comprising an illumination projector, which comprises a broadband illumination source panel and a polarizing structure to illuminate an ocular surface and adjacent structures of an eye and project a pattern on the ocular surface; an imaging system to form images; a detection system to record the images with a plurality of spectral channels in visible and near infrared spectra; and a computer to display and analyze the images. Also disclosed is a method of evaluating ocular surface health using a multispectral or hyperspectral ocular surface evaluating device, which comprises illuminating an ocular surface and adjacent structures of an eye with polarized light from an illumination projector; forming images with the imaging system; recording images formed on the detection system; digitally processing the recorded images; and analyzing the recorded images to evaluate ocular surface health with the computer.
    Type: Grant
    Filed: September 8, 2019
    Date of Patent: February 22, 2022
    Inventor: Aizhong Zhang
  • Patent number: 11253198
    Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: February 22, 2022
    Assignee: AccuVein, Inc.
    Inventors: Fred Wood, Ron Goldman, Stephen P. Conlon, Vincent Luciano
  • Patent number: 11246481
    Abstract: The present disclosure provides systems and methods for characterizing thin films, such as, for example, diagnosis of dry eye syndrome, thin-film optical metrology testing, etc. The present disclosure may be embodied as a tearscope, which is sometimes referred to herein as a Macroscopic Imaging Ellipsometer (MIE) because it may be considered to be an imaging ellipsometer with, for example, a field-of-view on the order of tens of millimeters or more (i.e., macroscopic), compared with conventional imaging ellipsometers, which usually employ microscope objectives and have fields-of-view of up to several hundred microns.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: February 15, 2022
    Assignee: University of Rochester
    Inventors: James M. Zavislan, Aizhong Zhang
  • Patent number: 11238279
    Abstract: According to various embodiments, an electronic device may include a first light emitter comprising first light emitting circuitry configured to output light of a first wave bandwidth, a second light emitter comprising second light emitting circuitry configured to output light of a second wave bandwidth, a camera including an image sensor configured to arrange one or more first pixels for sensing the light corresponding to the first wave bandwidth and the second wave bandwidth and one or more second pixels for sensing the light corresponding to the second wave bandwidth, and a processor. The processor may be configured to control the electronic device to output the first wave bandwidth light using a first light source and the second wave bandwidth light using a second light source, and a control circuit electrically coupled to the image sensor and connected to an application processor through a designated interface.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: February 1, 2022
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Woontahk Sung, Hwayong Kang, Jongsun Kim, Kihuk Lee, Bongchan Kim
  • Patent number: 11224342
    Abstract: The invention relates to a device and a method for examining the retinal vascular endothelial function of the vessels of the retina at the fundus (F) of a patient's eye. Using a fundus camera, the vessels of the retina are stimulated with flicker light during a stimulation phase and sequences of images of areas of the fundus (F) are recorded, from which vascular parameters are derived which describe the retinal vascular endothelial function of the vessels. By imaging a macula stop (MB), which covers the macula, onto the fundus (F), the fundus (F) can be illuminated with a higher light intensity, which improves the stimulation effect and the image quality and/or reduces the strain on the patient.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: January 18, 2022
    Inventors: Walthard Vilser, Jens Haueisen, Sascha Klee, Dietmar Link, Thomas Riemer, Martin Skorsetz
  • Patent number: 11219365
    Abstract: The present subject matter relates to an ophthalmologic imaging apparatus, which can capture reflex-free retinal images of a subject's eye. The imaging apparatus comprises light sources arranged on an illumination axis. A first shield placed at a distance from a first condenser lens, which is placed in front of a photographic light source on the illumination axis. The first shield has a central opaque portion on which an observation light source is mounted, and an outer pair of coaxial annular transparent regions. A diffuser is placed in front of the observation light source. A second shield has a central opening portion and mounted on the diffuser. The imaging apparatus further comprises a porosity mirror mounted on a porosity tube.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: January 11, 2022
    Inventors: Shanmuganathan Nagarajan, Anand Sivaraman
  • Patent number: 11219366
    Abstract: According to an embodiment of the present disclosure, there is provided a retina photographing apparatus including: a body unit including a case providing an outer appearance of the retina photographing apparatus, and a holder connected to the case and being mountable on an examinee's head; a retina photographing unit installed inside the case, and configured to irradiate light onto a retina of the examinee's left or right eye and to detect the light reflected from the retina to acquire an image of the retina; and a driving unit configured to move a position of the retina photographing unit inside the case in order to photograph both of the examinee's eyes.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: January 11, 2022
    Assignee: ROOTEEHEALTH, INC.
    Inventors: Kyung Min Kook, Su Ryeon Kim
  • Patent number: RE49023
    Abstract: A fundus observation apparatus that is capable of assisting an examiner in judging the presence or absence of abnormality in an examinee's eye based on a fundus tomographic image. The fundus observation apparatus includes an optical coherence tomography device that has an optical scanner for setting an image pickup position on a fundus of an examinee's eye, and is arranged to obtain a tomographic image of the fundus, and an information display unit that is arranged to display on a monitor the tomographic image obtained by the optical coherence tomography device and assisting information for assisting an examiner in performing judgment on the tomographic image, and the information display unit is arranged to change the assisting information based on image pickup information on the tomographic image.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: April 12, 2022
    Assignee: NIDEK CO., LTD.
    Inventors: Naoki Isogai, Toshio Murata