Including Eye Photography Patents (Class 351/206)
  • Patent number: 9839351
    Abstract: A method of generating a tomographic image using optical coherence tomography includes: a data obtaining step of obtaining a plurality of pieces of tomographic image data each indicating a tomogram at substantially the same position of an object; a removing step of removing an outlier from the plurality of pieces of tomographic image data; a computation step of computing a motion contrast value based on the plurality of pieces of tomographic image data from which the outlier is removed; and a generation step of generating a motion contrast image of the object based on the motion contrast value.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: December 12, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventor: Atsushi Goto
  • Patent number: 9833140
    Abstract: Portable corneal topographers and portable corneal topographer modules are disclosed. In one embodiment, a corneal topographer module comprises a housing having a first aperture and a second aperture formed therethrough; and a plurality of optical components disposed within the housing. The plurality of optical components are arranged to direct light generated by a light source through the first aperture to the cornea via a first optical channel when a cornea of a patient's eye is located adjacent to the first aperture; and direct reflected light from the cornea into the housing through the first aperture and to a light detector of a mobile device via a second optical channel when the corneal topographer module is mechanically coupled to the mobile device.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: December 5, 2017
    Assignee: SMART VISION LABS, INC.
    Inventor: Yaopeng Zhou
  • Patent number: 9826901
    Abstract: The present invention relates to an adaptor for a slit lamp microscope. According to one embodiment of the present invention, the invention provides the advantages of: facilitating the maintenance/repair of a slit lamp microscope since a camera member used for the slit lamp microscope is simply attached or detached; simply and easily inspecting and photographing a subject's eye; and obtaining a high-resolution video or image for the subject's eye at low costs.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: November 28, 2017
    Inventors: Dong Kwan Kim, Dong Sik Kim
  • Patent number: 9827066
    Abstract: Methods and systems for performing an ophthalmic surgical procedure include pulsed illumination of target tissue. The systems may include an illumination instrument arranged to illuminate tissue at a surgical site during the ophthalmic surgical procedure. A light source provides illumination to the illumination instrument for emission from the illumination instrument toward the surgical site. A controller communicates with the light source and activates the light source to provide illumination pulses at a frequency above the flickering perception in humans and with enough light for cameral exposure and human light perception. The light source pulses to minimize phototoxicity.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: November 28, 2017
    Assignee: NOVARTIS AG
    Inventor: Niels Alexander Abt
  • Patent number: 9826130
    Abstract: An infrared camera, comprising photosensitive element (101) capable of sensing infrared spectrum, gas discharge flash acting as flash light source (102), a first optical filter (103) filtering visible lights and allowing infrared light to transmit, and processing module (105) used to execute instructions, wherein the first optical filter is fixedly or removablely disposed in the emitted light path of the flash light source. Due to gas discharge flash filtering visible lights and acting as infrared light source, the camera could provide infrared lighting capability far better than infrared LED, improving the nighttime infrared photographing quality.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: November 21, 2017
    Assignee: Boly Media Communications (Shenzhen) Co., Ltd
    Inventors: Xiaoping Hu, Xia Shen
  • Patent number: 9820697
    Abstract: A lesion determination apparatus includes: a number-of-images acquiring unit configured to acquire and record, on occurrence of a direction change that is either a first state in which a second operation instruction is received immediately after receipt of a first operation instruction or a second state in which the first operation instruction is received immediately after a receipt of the second operation instruction, a number of one-directionally viewed images that is either a number of tomography images continuously viewed in response to continuous first operation instructions including the first operation instruction in the first state or a number of tomography images continuously viewed in response to continuous second operation instructions including the second operation instruction in the second state; and a locality determining unit configured to determine whether the object part is a focal lesion or a diffuse lesion based on a change in the number of one-directionally viewed images.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: November 21, 2017
    Assignee: PANASONIC CORPORATION
    Inventors: Kazutoyo Takata, Kazuki Kozuka, Kenji Kondo, Hirohiko Kimura, Toyohiko Sakai
  • Patent number: 9820646
    Abstract: An image processing apparatus converts an intensity distribution of at least one of a plurality of regions of a tomographic image of an eye by using an amount of conversion which is greater than an amount of conversion used to convert an intensity distribution of another one of the plurality of regions, the tomographic image being obtained by performing tomographic imaging on the eye by using optical interference.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: November 21, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventors: Hiroki Uchida, Yukio Sakagawa, Krzysztof Marek Piotrowski
  • Patent number: 9820645
    Abstract: The present invention relates to an ophthalmologic apparatus for acquiring depth information of an eye including a light source; a measurement optical path guiding measurement light; a reference optical path generating reference light; and a detector generating a detection signal containing an interference signal of the measurement light via the measurement optical path and the reference light coming from the reference optical path; an actuator driving at least part of the interference optical system to vary an optical path length difference between the measurement optical path and the reference optical path; a standard optical system including optical members disposed corresponding to the optical path length differences in one of the measurement optical path and the reference optical path. Optical members guide part of the measurement light or the reference light to the detector.
    Type: Grant
    Filed: July 30, 2015
    Date of Patent: November 21, 2017
    Assignee: NIDEK CO., LTD.
    Inventors: Masakazu Endo, Masaaki Hanebuchi, Yasuhiro Furuuchi
  • Patent number: 9820649
    Abstract: A three-dimensional tomographic image (B) is formed which is composed of a plurality of two-dimensional tomographic images obtained by scanning an ocular fundus. A contour of a certain 2D region (M1, M2, M3, M4) in the tomographic image is determined for each tomographic image, and the volume of a certain 3D region is calculated through correcting each area of the certain 2D region defined by the determined contour or its accumulated value using an image correction coefficient in accordance with the diopter of the subject's eye. Even for subjects' eyes of different diopters, the influence of the diopter correction is eliminated and a quantitative comparison of subjects' eyes of different diopters is possible.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: November 21, 2017
    Assignee: KOWA COMPANY, LTD.
    Inventors: Toshiaki Nakagawa, Yoshihiro Kakutani, Masaharu Mizuochi
  • Patent number: 9820650
    Abstract: An image processing apparatus obtains a moving image of an eye area, identifies a region of blood cells in the obtained moving image, and determines the number of determined regions of blood cells.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: November 21, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventors: Akihito Uji, Shigeta Arichika, Hiroshi Imamura
  • Patent number: 9814385
    Abstract: The invention relates to an ophthalmoscope comprising a camera and an associated illumination device; the invention further concerns a novel method for processing a plurality of images of the eye taken by said device; and software, typically included in said ophthalmoscope, for executing said method.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: November 14, 2017
    Assignees: London School of Hygiene and Tropical Medicine, The Greater Glasgow Health Board, The University Court of the University of St Andrews
    Inventors: Stewart Jordan, Mario Giardini, Iain Livingstone, Andrew Bastawrous
  • Patent number: 9814381
    Abstract: An ophthalmic apparatus is capable of communicating with a PDA device provided with a display unit and includes a main body that includes an image-capturing unit, the image-capturing unit obtaining a moving image of an eye to be examined (target eye) based on light returned from the target eye which is illuminated, the moving image of the target eye used by the ophthalmic apparatus for obtaining, based on an examination of the target eye, information regarding the target eye, a driving unit that drives the main body, a transmission unit that transmits, before the information regarding the target eye is obtained, a moving image signal of the obtained moving image to the PDA device, a reception unit that receives a control signal from the PDA device during transmission of the moving image signal, and a control unit that controls the driving unit based on the received control signal.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: November 14, 2017
    Assignee: CANON KABUSHIKI KAISHA
    Inventor: Koji Uchida
  • Patent number: 9808150
    Abstract: An image processing apparatus includes: a tomographic image acquisition unit that acquires a first tomographic image of a subject's eye captured at a first time point that is a past time point; a tomographic image capturing unit that acquires a second tomographic image of the subject's eye captured at a second time point later than the first time point; and an image display control unit that, if one image capturing region of an image capturing region of the first tomographic image and an image capturing region of the second tomographic image is larger than the other image capturing region, performs control to provide, on an image display portion, a display of both a tomographic image of only a partial region of the one image capturing region which is a corresponding region corresponding to the other image capturing region and a tomographic image of the other image capturing region.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: November 7, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventors: Tatsuya Tanaka, Keisuke Oyaizu
  • Patent number: 9808152
    Abstract: An anterior ocular segment optical coherence tomographic imaging device and an anterior ocular segment optical coherence tomographic imaging method that can accurately analyze the shape of a crystalline lens by identifying the boundary of each layer of the crystalline lens in a tomographic image of an anterior ocular segment of a subject's eye, which is taken by optical coherence tomography. A layer boundary detector calculates brightness gradients from brightness values in a tomographic image of an anterior ocular segment of a subject's eye, which is taken by optical coherence tomography, in a depth direction of the tomographic image from a cornea to a retina, detect edges b1, b2, b3, and b4 that are larger than a predetermined threshold, and identify a boundary of each layer of the crystalline lens L from positions of the edge b1, b2, b3, and b4.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 7, 2017
    Assignee: Tomey Corporation
    Inventors: Keiichiro Okamoto, Risa Higashita, Fushi Li, Makoto Kojima
  • Patent number: 9811159
    Abstract: Aspects of the present invention relate to methods and systems for imaging, recognizing, and tracking of a user's eye that is wearing a HWC. Aspects further relate to the processing of images reflected from the user's eye and controlling displayed content in accordance therewith.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: November 7, 2017
    Assignee: Osterhout Group, Inc.
    Inventors: Edward H. Nortrup, John N. Border, Ralph F. Osterhout, John D. Haddick, Robert Michael Lohse
  • Patent number: 9808153
    Abstract: A method, controller, and medium to control an adaptive optics scanning laser ophthalmoscope. Receiving from the ophthalmoscope a plurality of wavefront elements. Each element may be associated with an area of a beam of light received from a fundus. Each element includes shape data. The shape data represents a shape of a wavefront in a area of the beam. Each element includes status data. The status data is a confidence indicator of ability of the shape data to represent the shape of the wavefront with a particular level of accuracy. Calculating control data based on the shape data in the wavefront data and local gain. The local gain includes local gain elements. Each local gain elements is adjusted based on status data. Using the control data to adjust a shape of an illumination wavefront of an illumination beam used to illuminate the fundus.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: November 7, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventor: Koji Nozato
  • Patent number: 9801537
    Abstract: An eye fundus image photographing device and method that can acquire images of higher quality. The eye fundus image photographing device photographs a wide-angle eye fundus image on an appropriate exposure condition with respect to a peripheral area different from an optic disk region of an eye fundus area and detects the optic disk region from the wide-angle eye fundus image. Moreover, based on the detection result of the optic disk region, the eye fundus image photographing device photographs a narrow-angle eye fundus image which assumes an area of the optic disk region as an object, on an appropriate exposure condition with respect to the area of the optic disk region. Further, the eye fundus image photographing device generates a synthetic eye fundus image of a high dynamic range by synthesizing the wide-angle eye fundus image and the narrow-angle eye fundus image.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: October 31, 2017
    Assignee: SONY CORPORATION
    Inventor: Seiji Kobayashi
  • Patent number: 9804389
    Abstract: An eye tracker having a waveguide for propagating illumination light towards an eye and propagating image light reflected from at least one surface of an eye, a light source optically coupled to the waveguide, and a detector optically coupled to the waveguide. Disposed in the waveguide is at least one grating lamina for deflecting the illumination light towards the eye along a first waveguide path and deflecting the image light towards the detector along a second waveguide path.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: October 31, 2017
    Assignee: DIGILENS, INC.
    Inventors: Milan Momcilo Popovich, Jonathan David Waldern, Alastair John Grant
  • Patent number: 9795290
    Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: October 24, 2017
    Assignee: TearScience, Inc.
    Inventors: Stephen M. Grenon, Scott Liddle, Donald R. Korb
  • Patent number: 9795291
    Abstract: An optical coherence tomography device includes: an OCT optical system configured to obtain a OCT signal; a front observation optical system configured to obtain a front image of the test substance; and a controller is configured to: control the OCT optical system to obtain first temporally different OCT signals with respect to the test substance; control the front observation optical system to obtain a first front image of the test substance at the time the first OCT signals are obtained; control the front observation optical system to obtain a second front image of the test substance after that; determine whether or not the plurality of first OCT signals are good based on a positional deviation between the first and second front images; and obtain motion contrast data of the test substance when it is determined that the plurality of first OCT signals are good.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: October 24, 2017
    Assignee: NIDEK CO., LTD.
    Inventors: Norimasa Satake, Yukihiro Higuchi, Naoki Takeno
  • Patent number: 9788717
    Abstract: A method of reducing jitter error in a laser scanning system adapted to produce a scanned image including a number of lines of an object. The method includes the steps of providing a reference object arranged such that the scanned image produced by the laser scanning system includes a reference image of the reference object, processing the reference image to calculate an error arising from non-repeatable displacement of the lines of the reference image, and adjusting at least one operating parameter of the laser scanning system in response to the calculated error.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: October 17, 2017
    Assignee: OPTOS PLC
    Inventor: Hind Azegrouz
  • Patent number: 9788713
    Abstract: Systems and methods for modifying an eye including a light source with light elements, a photodetector producing a signal representing images of the light elements and corresponding to locations on an ocular surface, an optical system directing light from the light elements reflected by the ocular surface onto the photodetector, a memory including code for processing the signal, and a processor for executing the code and outputting shape data for use in calculating a treatment plan for the eye. The code includes instructions for determining the shape data based on a combination of zonal reconstruction and polynomial fitting using the plurality of images.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 17, 2017
    Assignee: AMO Wavefront Sciences LLC.
    Inventor: Stephen W. Farrer
  • Patent number: 9788718
    Abstract: A surgical microscope for imaging structures of an eye includes: a front optical unit, an illumination device which has an illumination-radiation-emitting illumination source and which illuminates the retina of the eye with an illumination spot via an illumination beam path which extends through the front optical unit, a camera and an adjustable camera optical unit disposed upstream thereof, an imaging beam path which extends through the front optical unit and the camera optical unit, and a control device which controls the camera optical unit and sets the latter in such a way that the retina of the eye in the region of the illumination spot is imaged on the camera. The control device varies a focusing state of the camera optical unit and, as a result thereof, records a plurality of images of the retina in the region of the illumination spot, the images being focused in different depth planes, and establishes a refractive value of the eye from these images.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: October 17, 2017
    Assignee: Carl Zeiss Meditec AG
    Inventors: Christoph Hauger, Artur Hoegele, Peter Reimer, Holger Matz, Joachim Steffen
  • Patent number: 9782065
    Abstract: Provided is a snapshot spectral domain optical coherence tomographer comprising a light source providing a plurality of beamlets; a beam splitter, splitting the plurality of beamlets into a reference arm and a sample arm; a first optical system that projects the sample arm onto multiple locations of a sample; a second optical system for collection of a plurality of reflected sample beamlets; a third optical system projecting the reference arm to a reflecting surface and receiving a plurality of reflected reference beamlets; a parallel interferometer that provides a plurality of interferograms from each of the plurality of sample beamlets with each of the plurality of reference beamlets; an optical image mapper configured to spatially separate the plurality of interferograms; a spectrometer configured to disperse each of the interferograms into its respective spectral components and project each interferogram in parallel; and a photodetector providing photon quantification.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: October 10, 2017
    Assignee: IDX, LLC
    Inventors: Michael D. Abramoff, Edward DeHoog
  • Patent number: 9782072
    Abstract: An ophthalmologic imaging apparatus that captures an image of a subject's eye is provided. The apparatus includes a focusing unit configured to focus light returned from the subject's eye that is illuminated by the light of a first wavelength, onto an imaging unit, and a moving unit configured to move the focusing unit based on an optical path length difference between the light of the first wavelength and the light of a second wavelength that is different from the first wavelength when light returned from the subject's eye that is illuminated by the light of the second wavelength is focused onto the imaging unit.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: October 10, 2017
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Hideyuki Ooban, Yasuhiro Nakahara, Hiroshi Itoh
  • Patent number: 9782070
    Abstract: The fundus photographing apparatus of the present invention includes an illumination light source that generates illumination light flux for illuminating a fundus (of a subject eye), a scanning optical system that converts the illumination light flux from the illumination light source unit into spot light to scan the fundus in two-dimensional directions of a horizontal direction and a vertical direction by the spot light, a light receiver that receives reflected light from each portion of the fundus illuminated by the spot light, and a fundus image acquiring unit that acquires a fundus image based on a signal from the light receiver, wherein the scanning optical system is provided with a scanner including a reflection mirror plate that rotates about orthogonal two axes to simultaneously deflect the spot light in the vertical direction and the horizontal direction for scanning.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: October 10, 2017
    Assignee: Kabushiki Kaisha TOPCON
    Inventors: Atsushi Utsunomiya, Hirotake Maruyama, Tomoyoshi Abe, Yasufumi Fukuma
  • Patent number: 9775515
    Abstract: A system for multi-scale closed-loop eye tracking to compensate for translation and rotation motion while imaging in vivo a surface area of an internal structure of an eye of a subject includes a narrow field imaging device optically coupled to an optical path to receive light reflected from the surface area of the structure of the eye. A wide field camera is optically coupled to the optical path by a beam splitter disposed in the optical path. A tracking mirror is disposed in the optical path between the beam splitter and the structure of the eye. A control process algorithm actively compensates substantially in real time for both translational and rotational movements of the eye. A system where a torsional correction device causes a rotating movement of a subject's head and a method for multi-scale closed-loop eye tracking are also described.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: October 3, 2017
    Assignee: University of Rochester
    Inventors: Qiang Yang, Jie Zhang
  • Patent number: 9775508
    Abstract: A computer-implementable method of analyzing tissues of a retina. A polarization-sensitive (PS-OCT) image data set of the retina is received from a polarization-sensitive device, each element in the polarization-sensitive image data set being associated with an intensity value ({I1, . . . , IL}) and a polarization direction ({P1, . . . , PL}). A likelihood score is determined for each element of the polarization-sensitive image data set based on the intensity value of the element and a degree of divergence (?*TP or D2) of the polarization direction associated with the element from a reference polarization direction (?*) associated with the polarization sensitive image data set, wherein the likelihood score indicates whether said element is drawn from a directionally polarized distribution or a depolarizing distribution, Elements of the polarization-sensitive image data set are classified using the determined likelihood scores to analyze tissues of the retina.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: October 3, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventors: Andrew Docherty, Barry James Drake
  • Patent number: 9775514
    Abstract: An apparatus for measuring a fundus of a subject. The apparatus includes a focusing unit which adjusts a defocus of the apparatus. The focusing unit includes a first focusing mirror and a second focusing mirror. The first focusing mirror and second focusing mirror are arranged so that an incident beam from the light source entering the focusing unit and an emitted beam exiting the focusing unit are substantially parallel to each other. Adjustment of the defocus is accomplished by moving both first focusing mirror and second focusing mirror such that incident beam and emitted beam remain substantially parallel to each other. The apparatus includes a wavefront sensor for detecting a shape of a wavefront. The apparatus includes a wavefront correction device. The wavefront correction device adjusts a wavefront of the light from the light source based on the shape of the wavefront detected by the wavefront sensor.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: October 3, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventor: Kenichi Saito
  • Patent number: 9773170
    Abstract: Embodiments that relate to determining an estimated pupil region of an eye are disclosed. In one embodiment a method includes receiving an image of an eye, with the image comprising a plurality of pixels. A rough pupil region is generated using at least a subset of the plurality of pixels. A plurality of pupil boundary point candidates are extracted from the rough pupil region, with each of the candidates weighted based on color values of at least two neighbor pixels. A parametric curve may be fitted to the weighted pupil boundary point candidates to determine the estimated pupil region of the eye of the user.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: September 26, 2017
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Milan Vugdelija, Djordje Nijemcevic, David Zachris Nister, Christopher Maurice Mei, Chandra Sekhar Gatla
  • Patent number: 9767556
    Abstract: There is provided an eye-fundus image output device including a selection unit configured to select a site of a presented eye-fundus image, an optimization unit configured to optimize an image of the selected site, and an output unit configured to output an image in which the selected site has been optimized.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: September 19, 2017
    Assignee: SONY CORPORATION
    Inventors: Tomoyuki Ootsuki, Seiji Kobayashi, Kazuki Aisaka
  • Patent number: 9757026
    Abstract: An ophthalmic apparatus which photographs an endothelial cell and measures a coat thickness of a cornea of an eye to be examined in a non-contact manner; comprising an image pickup unit (19) for photographing a corneal endothelium of the eye to be examined, a control unit (49) for detecting a cell wall of the endothelial cell from a corneal endothelial image photographed by the image pickup unit and for performing an image processing of hatching the cell wall with a boundary line, a display unit (54) for displaying an analytical image in which the cell wall hatched with the boundary line, and an operation unit (55), wherein the control unit changes the shading of the boundary line based on an input from the operation unit.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: September 12, 2017
    Assignee: Kabushiki Kaisha TOPCON
    Inventor: Hiroki Oe
  • Patent number: 9757027
    Abstract: A system and method are described for performing tear film structure measurement. A broadband light source illuminates the tear film. A spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera performs large field of view imaging of the tear film, so as to obtain color information for all points of the tear film imaged by the color camera. A processing unit calibrates the camera at the point measured by the spectrometer so that the color obtained by the camera at the point matches the color of the spectrometer at the same point. The processing unit determines, from the color of respective points of the calibrated camera, thicknesses of one or more layers of the tear film at the respective points. Other applications are also described.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: September 12, 2017
    Assignee: ADOM, Advanced Optical Technologies Ltd.
    Inventors: Yoel Arieli, Yoel Cohen, Shlomi Epstein, Dror Arbel, Ra'anan Gefen
  • Patent number: 9759545
    Abstract: A luminous flux including laser light of different wavelengths outgoing from a light source unit is split into two luminous fluxes, the first luminous flux is focused on a sample with an objective lens, and the second luminous flux functions as reference light without radiating it onto the sample. Signal light reflected from the sample and the reference light are multiplexed by a polarized beam splitter and are made to interfere on four photodetectors out of phase in a photodetection unit. A signal processing unit acquires the optical axis distribution of an object in the sample by using the outputs of the plural photodetectors for every input wavelength, acquiring a detection signal and calculating the ratio of intensities of the detection signals at the different input wavelengths for every position in the sample.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: September 12, 2017
    Assignee: HITACHI-LG DATA STORAGE, INC.
    Inventors: Masaki Mukoh, Kentaro Osawa, Tatsuro Ide
  • Patent number: 9757023
    Abstract: The invention relates to methods and systems for automatically detecting an optic disc in a retinal fundus autofluorescence image. A monochromatic image of a retina is obtained by stimulated autofluorescence. The image is processed using filters and machine learning to identify blood vessel segments and to identify pixels as possible optic disc pixels. The possible optic disc pixels are grouped into clusters, and a best fit circle (or portion thereof lying within the image) is fitted to each cluster. The circle may be enlarged to improve image contrast at the circumference of the circle. Blood vessel segments that intersect the circle are identified, and metrics are derived from such intersecting blood vessel segments. These metrics are assessed by machine learning processes to determine the probability that each cluster contains the optic disc, and the contours of the optic disc are further determined by analysis of the possible optic disc pixels.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: September 12, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Kanishka T. Jayasundera, Matthew K. Johnson-Roberson
  • Patent number: 9750402
    Abstract: A disclosed ophthalmologic apparatus includes an image acquisition unit configured to acquire a fundus image of an eye to be examined on the basis of returning light from a fundus that is obtained by irradiating the fundus of the eye with light; and a correction unit configured to correct the fundus image in accordance with a degree of clouding of a clouded portion of the eye such that, among color components contained in the fundus image, a ratio of a color component, in the fundus image, that is scattered by a clouded portion of the eye at a higher rate increases against a ratio of another color component.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: September 5, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventor: Mitsuhiro Ono
  • Patent number: 9750406
    Abstract: The invention relates to a method for the detection of visual function losses. The method comprises analysing the optical quality of a patient's eye based on one or more retinal images thereof or based on information relating to retinal images corresponding to an eye having an anterior segment and intraocular means that are healthy. The method comprises: detecting a visual function loss of the visual system of functional or pathological etiology, based on the result of the aforementioned analysis; and determining if this loss is due to a reduced and/or limited neural response, which induces alterations in the innervation of the intrinsic ocular muscles of the eye.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: September 5, 2017
    Assignee: UNIVERSITAT POLITECNICA DE CATALUNYA
    Inventors: Jaume Pujol Ramo, Juan Carlos Ondategui Parra, Maritxell Vilaseca Ricart, Montserrat Arjona Carbonell, Rosa BorrĂ¡s Garcia
  • Patent number: 9743830
    Abstract: A fundus photography device includes: an OCT optical system configured to detect interference between a measurement light from a fundus of a subject's eye and a reference light from a reference optical path; a fundus photography optical system configured to detect a reflected light from the fundus; a controller configured to generate a tomographic image of the fundus and a first front image of the fundus based on an output signal from the OCT optical system, and generate a second front image of the fundus based on an output signal from the fundus photography optical system. The controller is configured to cause simultaneous display of the first front image and the second front image in different display regions on a monitor.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: August 29, 2017
    Assignee: NIDEK CO., LTD.
    Inventors: Norimasa Satake, Naoto Honda
  • Patent number: 9737210
    Abstract: The present invention provides a system and a method for performing a cataract surgery. The system of the present invention includes an optical coherence tomography apparatus, an image capturing device, and a central processing unit. The method includes imaging optical coherence tomography of a patient's eye using the optical coherence tomography apparatus, capturing the patient's optical coherence tomography with the image capturing device, generating a 3D image and coordinates of the patient's eye, and determining a central location of a pupillary margin and an iridocorneal angle using a central processing unit. The center of the anterior capsule of the human crystalline lens is then calculated by matching the iridocorneal angle to the central location of the pupillary margin.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: August 22, 2017
    Assignee: the Catholic University Industry Academic Cooperation Foundation
    Inventor: Choun-ki Joo
  • Patent number: 9737204
    Abstract: The invention provides an apparatus and method for illuminating, imaging and treating the retina of an eye. The apparatus (10) comprises at least one light source (16), wherein the at least one light source (16) is adapted to provide collimated light (20) from a plurality of point sources (22), and wherein each point source (22) lies on an arc (18), and wherein the at least one light source (16) is configured to direct collimated light (20) from each point source (22) along the radius (24) of the arc (18) towards a center point (26) of the arc (18), and wherein, in use, the apparatus (10) is arranged such that the center point (26) of the arc (18) is substantially coincident with the pupillary point (40) of the eye (14), such that collimated light (20) is transmitted from the point source (22) through the pupillary point (40) of the eye (14) to illuminate the retina (12).
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: August 22, 2017
    Assignee: OPTOS PLC
    Inventors: Robert Wall, Derek Swan, Dan Gray
  • Patent number: 9737208
    Abstract: The present invention relates to the field of instruments for imaging internal structures of the human body, and in particular of the eye. More specifically it relates to an optimized method and an optical coherence tomography system thereof.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: August 22, 2017
    Assignee: COSTRUZIONI STRUMENTI OFTALMICI C.S.O. S.R.L.
    Inventors: Gabriele Vestri, Claudio De Mauro, Domenico Alfieri, Silvano Pieri, Francesco Versaci
  • Patent number: 9737205
    Abstract: Disclosed is a method for analyzing retinal image data obtained using spectral-domain optical coherence tomography (SD-OCT). The image data comprise a cross-section of the retina and an en face image of the retina of a subject having AMD (age-related macular degeneration). The image data are processed to obtain an accurate structure showing locations, shape, size, and other data on drusen (deposits under the retina). This structural information is processed to extract quantitative drusen features that are indicative of a risk of progression of AMD from the dry form to the wet form of the disease in a given subject and defined time period, including short time intervals (one year or less). Relevant drusen features used include number, en face area and volume of drusen detected; shape of drusen detected; density of drusen; and reflectivity of drusen.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: August 22, 2017
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Daniel L. Rubin, Luis de Sisternes Garcia
  • Patent number: 9734418
    Abstract: A handheld electronic device includes a camera module, a flashlight module and a processor. The processor is configured to generate a flashlight indication signal having one or more pulse(s) distributed over time, direct the flashlight module to turn on a first light and a second light at different time based on the flashlight indication signal, direct the camera module to take pictures to obtain a stream of biological characteristic images comprising one or more first biological characteristic image(s) obtained when the first light is turned on and one or more second biological characteristic image(s) obtained when the second light is turned on, and compare the first biological characteristic image(s) with a first reference signature and compare the second biological characteristic image(s) with a second reference signature to obtain an identity authentication result.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: August 15, 2017
    Assignee: HTC CORPORATION
    Inventor: Fu-Cheng Fan
  • Patent number: 9730579
    Abstract: The present method describes a new method for the measurement of dark adaptation. The dark adaptation status of subjects may then be used to identify those subjects who are at risk of developing and/or who are currently suffering from a variety of disease states having their clinical manifestations in impaired dark adaptation. The disease states include, but are not limited to, age related macular degeneration, vitamin A deficiency, Sorsby's Fundus Dystrophy, late autosomal dominant retinal degeneration, retinal impairment related to diabetes and diabetic retinopathy. An apparatus for administering the test method described is also provided.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: August 15, 2017
    Assignee: The UAB Research Foundation
    Inventors: Gregory R Jackson, Cynthia Owsley
  • Patent number: 9723978
    Abstract: A fundus photography device includes: a fundus illumination optical system that illuminates a fundus of an eye by illumination light; a fundus photography optical system; an OCT optical system; an anterior chamber observation optical system for observing an anterior chamber observation image of the eye illuminated by the anterior chamber illumination light source; a first wavelength separation member that sets a first optical axis commonly shared by the fundus illumination optical system and the fundus photography optical system to be coaxial with a second optical axis commonly shared by the OCT optical system and an anterior chamber observation optical system; and a second wavelength separation member that forms the second optical axis by setting an optical axis of the OCT optical system to be coaxial with an optical axis of the anterior chamber observation optical system.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: August 8, 2017
    Assignee: NIDEK CO., LTD.
    Inventors: Koichi Ito, Naoto Honda
  • Patent number: 9723983
    Abstract: A corneal endothelial cell photographing apparatus for photographing endothelial cells of a patient eye's cornea, includes: a cornea photographing optical system including an imaging device and configured to project light toward the cornea and photograph the corneal endothelial cells through the imaging device; a light projecting optical system to project detection light in a first oblique direction to the cornea to detect a focus state of the cornea photographing optical system relative to the cornea; a detecting optical system including a detector with arranged pixels and configured to receive, in a second oblique direction opposite to the first oblique direction, corneal reflection light resulting from the detection light and including reflection light from the corneal endothelium through the detector, and detect an intensity distribution of the corneal reflection light in a depth direction; and a controller to cause a monitor to display the intensity distribution output from the detector.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: August 8, 2017
    Assignee: NIDEK CO., LTD.
    Inventors: Kazunari Shimizu, Kenji Nakamura, Yusuke Sakashita
  • Patent number: 9718405
    Abstract: A collision avoidance and/or pedestrian detection system for a large passenger vehicle such as commuter bus, which includes one or more exterior and/or interior sensing devices positioned strategically around the exterior and interior of the vehicle for recording data, method for avoiding collisions and/or detecting pedestrians, and features/articles of manufacture for improving same, is described herein in various embodiments. The sensing devices may be responsive to one or more situational sensors, and may be connected to one or more interior and/or exterior warning systems configured to alert a driver inside the vehicle and/or a pedestrian outside the vehicle that a collision may be possible and/or imminent based on a path of the vehicle and/or a position of the pedestrian as detected by one or more sensing devices and/or situational sensors.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: August 1, 2017
    Assignee: Rosco, Inc.
    Inventors: Benjamin Englander, Julian Serer
  • Patent number: 9706918
    Abstract: A modular lens adapter system or kit is provided for mobile anterior and posterior segment ophthalmoscopy. Equipped with various lens adapter modules, respective lenses and a mobile imaging device, a user is provided with tools for various mobile ophthalmoscopy imaging applications. Eye care practitioners can use their existing lenses to customize the modular lens adapter system in a cost-effective way, which allows for mobile and remote capture, viewing, and utilization of clinical images. The various modules are also adaptable to nearly any type of phone or tablet regardless of its dimensions or presence of a protective case. The invention also addresses the need for fewer, smaller, less expensive, and easier to use ophthalmic imaging equipment, which is further important in enabling a broad base of users.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: July 18, 2017
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: David Myung, Robert Tienhan Chang, Lingmin He, Alex Nugent, Huynh P. Van, Ira G. Wong, Alexandre Jais, Mark Blumenkranz
  • Patent number: 9706912
    Abstract: An optical measurement system and method measure a characteristic of a subject's eye. The optical measurement system receives from an operator, via a user interface of the optical measurement instrument, a begin measurement instruction indicating the start of a measurement period for objectively measuring at least one characteristic of the subject's eye. Subsequent to receiving the begin measurement instruction, the optical measurement system determines whether a criterion associated with the tear film quality of the subject's eye is not satisfied. In response to determining that the criterion is not satisfied, the optical measurement instrument takes one or more corrective actions to measure the characteristic of the subject's eye under a condition wherein the criterion is satisfied.
    Type: Grant
    Filed: July 1, 2015
    Date of Patent: July 18, 2017
    Assignee: AMO WAVEFRONT SCIENCES, LLC
    Inventors: Richard J. Copland, John G. Dixson
  • Patent number: 9700205
    Abstract: Provided is an ophthalmologic apparatus including one dichroic mirror, which is arranged eccentrically with respect to an optical axis of light from an eye to be inspected to separate the light from the eye to be inspected; another dichroic mirror, which is configured to separate light separated by the one dichroic mirror by being transmitted through the one dichroic mirror; and a positive lens, which is configured to guide the light from the eye to be inspected to the one dichroic mirror as convergent light, and to guide the light from the eye to be inspected to the another dichroic mirror as divergent light, wherein an eccentric section of the one dichroic mirror and an eccentric section of the another dichroic mirror have a positional relationship of being substantially perpendicular to each other and having substantially the same eccentric amount, to thereby correct astigmatism.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: July 11, 2017
    Assignee: Canon Kabushiki Kaisha
    Inventors: Shoichi Yamazaki, Kazuhiro Matsumoto, Nobuhiro Tomatsu