Abstract: Both visible and IR cameras are integrated without an increase in an optical stack height of a surgical microscope used for ophthalmic surgery. The IR camera may be used to directly and intraoperatively capture a scanning OCT measurement beam, which uses NIR light that is invisible to the human eye. An IR image from the IR camera taken from the same surgical field as displayed intraoperatively to a user of the surgical microscope may be displayed in an ocular to the user, enabling visualization of a location of an OCT scan along with actual visible images of the surgical field.

Abstract: A system and a method for testing a visual field of a subject are described. The method includes determining inter-eye distance of the subject. Visual stimuli are displayed on a left display region and a right display region of a two-dimensional display to the subject based on the determined inter-eye distance. The left display region is configured to display content specific to the left eye and the right display region is configured to display content specific to the right eye of the subject. Subject responses to the visual stimuli are tracked. Based on the subject responses, a condition of the visual field of each eye the subject is evaluated and then results of the evaluation describing the subject's visual field condition is reported or stored.

Abstract: A keratometer for intra-surgery measurements mounted under a surgical microscope includes a Placido ring illuminating a patient's eye; a video camera; a beamsplitter directing a Purkinje image of the Placido ring to the video camera; a fixation light directing a beam for patient eye fixation, fixation confirmation or creating a red reflex effect to enhance IOL imaging and cataract visualization; a processor configured to determine the refractive characteristics and keratometer parameters of the patient's eye and to execute a digital image enhancement method to outline IOL features to help IOL alignment; and a digital display displaying the keratometer parameters and surgical guidance information for a surgeon.

Abstract: Systems and methods for surveying the sclera are provided. In some aspects, a method for generating a design for a prosthetic lens for an eye of a subject includes arranging an eye of a subject at a distance from a plurality of illumination sources and a plurality of imaging devices, projecting light onto the eye of the subject using the illumination sources, acquiring image data of the eye of the subject and the light using the plurality of imaging devices, generating a three dimensional map of the eye, including the sclera, using the image data; and designing, using the three dimensional map of the eye for the lens that fits over a cornea of the eye to engage the sclera and form a fluid pocket between the prosthetic lens that surrounds the cornea.

Abstract: An image processing system includes: an analysis unit configured to obtain information indicating a degree of curvature of a retina from a tomographic image of an eye to be examined; and an obtaining unit configured to obtain a category of the eye to be examined based on an analysis result.

Abstract: A system for photonic illumination for biometric identification and pupillometry. The system includes at least one light source configured for illuminating coherent beam including spatial superposition of at least a first wavelength and a second wavelength, the first wavelength is in the visible spectrum and the second wavelength is in the infrared spectrum. The system further includes an LCD dot array disposed along optical path of the beam such that the beam provides a spatially selective illumination having a cross section including an array of discrete pixels and an optical system for illuminating a human eye with the spatially selective illumination and for reflecting infrared light in the spatially selective illumination towards a camera disposed along an optical axis such that an image obtained by the camera is superimposed of the illuminated eye and the infrared light reflected by the optical system.

Abstract: A method for forming an offset model is described. The offset model represents an estimated offset between a limbus center of a user eye and a pupil center of the user eye as a function of pupil size. The approach includes sampling a set of limbus center values, sampling a set of pupil center values, and sampling a set of radius values. The offset model is formed by comparing a difference between the set of limbus center values and the set of pupil center values at each of the radius values. A system and a computer-readable storage device configured to perform such a method are also disclosed.

Abstract: A scanning-type image acquisition device includes: drivers that respectively vibrate in an x direction and a y direction that are perpendicular to a longitudinal axis of an optical fiber that guides illumination light from a light source and cause a tip of the optical fiber to be spirally scanned on a subject; a drive-signal generating circuit that generates drive signals for driving the drive units; an adjustment section that adjusts the drive signals generated by the drive-signal generating circuit and generates position reference data; a photodetector that detects scattered light of the illumination light at each scanning position of an illumination light spot on the subject due to the drivers; and an image generating circuit that generates an image by arranging intensity values of the scattered light detected by the photodetector in pixels in accordance with the position reference data output from the adjustment section.

Abstract: The present application describes the addition of various feedback mechanisms including visual and audio feedback mechanisms to an ophthalmic diagnostic device to assist a subject to self-align to the device. The device may use the visual and non-visual feedback mechanisms independently or in combination with one another. The device may provide a means for a subject to provide feedback to the device to confirm that an alignment condition has been met. Alternatively, the device may have a means for sensing when acceptable alignment has been achieved. The device may capture diagnostic information during the alignment process or may capture after the alignment condition has been met.

Abstract: Systems and methods capture light reflected back from a patient's fundus and compares the resulting images to prior images, to determine if the patient is experiencing intraocular inflammation or atrophy.

Abstract: An apparatus includes an interference optical system configured to acquire a tomographic image of an eye by using interference light between return light from the eye irradiated with measurement light and reference light corresponding to the measurement light, a determination unit configured to determine, by using at least one of information about an acquisition time for acquiring the tomographic image and information about an imaging view angle of the tomographic image, a search range for searching for a position corresponding to a first tomographic image of the eye, the position being in a second tomographic image of the eye, and the second tomographic image having been acquired at a time different from a time when the first tomographic image is acquired, and a registration unit configured to perform registration of the first tomographic image and the second tomographic image by using information about the determined search range.

Abstract: An optical coherence tomography (OCT) apparatus includes an optical source module comprising two or more selectable optical sources or an optical source configured to selectively operate in two or more source operating modes, or a combination of both, and further comprises an OCT engine coupled to the optical source module, the OCT engine comprising an OCT interferometer. The OCT apparatus still further includes a mode-switching optics module coupled to the OCT engine and comprising one or more swappable, selectable, or adjustable optical components, such that the mode-switching optics module is configured to selectively provide two or more optical configurations for the optical path between the OCT engine and an imaged object, according to two or more corresponding operating modes.

Abstract: A-lines are obtained from an OCT scan of the eye, some of which pass through the iris and the lens and some of which pass through the lens but not the iris. An interface is detected from the A-lines; at least some of this interface is assumed to correspond to either the anterior or posterior of the iris. For each A-line, a first metric is derived from pixels near the detected first interface, such that the first metric reflects an OCT signal intensity associated with the interface, and a second metric is derived from pixels further from the interface, such that the second metric reflects OCT signal attenuation below the detected interface. An attenuation parameter is calculated for each A-line, based on the first and second metrics, and the iris's edge is detected by determining whether each A-line passes through the iris, based on the attenuation parameter.

Abstract: Method for determining the refractive index (n) of a material of a contact lens, in particular of a soft contact lens, the contact lens (1) having a first surface and a second surface defining a lens geometry there between, by measuring the wavefront issued by the contact lens (1) with a wavefront sensor (4), obtaining data of the geometry of at least one section of the contact lens (1) with an optical coherence tomography system (3) and communicating the geometry of the at least one section of the contact lens (1) from the optical coherence tomography system (3) to an analyzer, particularly a computer, and determining the refractive index (n) of the material of the contact lens from the geometry of the at least one section of the contact lens and from the wavefront issued by the contact lens (1).

Abstract: A biological object observation system includes an observation optical unit, a photodetector, a display unit, a detection unit, and a processor. The observation optical unit includes an optical system that guides a luminous flux from a biological object and a drive unit that drives the optical system. The photodetector receives optical information in accordance with the biological object. The display unit displays an observation image of the biological object generated on the basis of the optical information. The detection unit detects one of a position and a movement of an object in a display region of the displayed observation image. The processor controls the drive unit in accordance with the one of the position and the movement of the object that is detected.

Abstract: The present invention relates to a novel method and system for crater detection in planetary data based on marked point processes (MPP), effective for various object detection tasks in Earth observation, and for planetary image registration. The resulting spatial features are exploited for registration, together with fitness functions based on the MPP energy, on the mean directed Hausdorff distance, and on the mutual information. Two different methods—one based on birth-death processes and region-of-interest analysis, and the other based on graph cuts and decimated wavelets—are included within the present framework. Experimental results confirmed the effectiveness of the present invention in terms of crater detection performance and sub-pixel registration accuracy.

Abstract: An optical measurement system method for measuring a characteristic of a subject's eye use a probe beam having an infrared wavelength in the infrared spectrum to measure a refraction of the subject's eye at the infrared wavelength; capture at least two different Purkinje images at two different corresponding wavelengths from at least one surface of the lens of the subject's eye; determine from the at least two different Purkinje images a value for at least one parameter of the subject's eye; use the value of the at least one parameter to determine a customized chromatic adjustment factor for the subject's eye; and correct the measured refraction of the subject's eye at the infrared wavelength with the customized chromatic adjustment factor to determine a refraction of the subject's eye at a visible wavelength in the visible spectrum.

Abstract: An example method of controlling an electronic device worn by a user includes constructing a user model by training a content feature according to response characteristics of an eye of a user who wears the electronic device, and in response to a content feature stored in the user model being detected from reproduced content during content reproduction, processing the reproduced content based on response characteristics of the eye of the user corresponding to the detected content feature.

Abstract: Systems and methods for monitoring eye health. The systems and methods monitor eye health by measuring scleral strain by way of an implantable monitor, a wearable monitor configured in eyeglasses, or an external monitor using a portable tablet computing device. Certain embodiments of the strain monitor may be utilized to measure the strain on any surface to which it is attached, including, but not limited to, the skin of a patient or the surface of a structure such as a building or a bridge.

Abstract: Disclosed is an LED arrangement for a microscopy instrument (200 FIG. 2) comprising a light emitting area (112), and a part-spherical solid and light transmissive cap (120), in light communication with the light emitting area, the cap having a hemispherical surface (126) including a portion (124) at which light from the light emitting area is reflected and a portion (128) at which light from the emitter can exit the cap, in order to provide a usable light cone L which includes light recycled from the more divergent emitted light, and is thereby more intense.

Abstract: The disclosed embodiments illustrate methods and systems for training users in sports using mixed reality. The method includes retrieving data from athletes wearing helmets, wearable glasses, and/or motion-capture suits in real time. The helmets and the wearable glasses are integrated with mixed-reality technology. Further, physical performance data of the athletes is captured using a variety of time-synchronized measurement techniques. Thereafter, the athletes are trained using the captured data and audio, visual and haptic feedback.

Abstract: An optical coherence tomography (OCT) system and method for cross view imaging using at least two B-scan images transformed and coupled to each other at an angle to generate a cross view image.

Abstract: A method of generating three dimensional shapes for a cornea and lens of an eye, the method including illuminating an eye with multiple sections of light and obtaining multiple sectional images of said eye based on said multiple sections of light. For each one of the obtained multiple sectional images, the following processes are performed: a) automatically identifying arcs, in two-dimensional space, corresponding to anterior and posterior corneal and lens surfaces of the eye by image analysis and curve fitting of the one of the obtained multiple sectional images; and b) determining an intersection of lines ray traced back from the identified arcs in two-dimensional space with a known position of a section of space containing the section of light that generated the one of the obtained multiple sectional images, wherein the determined intersection defines a three-dimensional arc curve.

Abstract: A method for imaging retinal structures involves offsetting an imaging aperture from the center of the reflected/scattered light distribution. Images are obtained with the imaging aperture at multiple offsets with respect to the center. The various obtained images are co-registered to a reference confocal image in a reference wavelength and averaged to generate high signal to noise ratio images. The images may be combined in various ways to enhance the contrast of retinal structures that would not be visible in confocal images.

Abstract: Methods and systems for capturing motion and/or determining the shapes and positions of one or more objects in 3D space utilize cross-sections thereof. In various embodiments, images of the cross-sections are captured using a camera based on reflections therefrom or shadows cast thereby.

Abstract: Provided is an image processing apparatus including: a data acquiring unit configured to acquire a plurality of pieces of tomographic data, which are obtained by performing optical coherence tomographic imaging of an object to be inspected through use of measuring light a plurality of times; a noise acquiring unit configured to acquire a noise characteristic of the tomographic data; a coefficient determining unit configured to determine a weighting coefficient corresponding to each pixel position in a tomographic image generated from the tomographic data based on the plurality of pieces of tomographic data and the noise characteristic; a changing unit configured to change a value of the tomographic data based on the weighting coefficient; and an image generating unit configured to generate the tomographic image based on the tomographic data that has the value changed.

Abstract: An eye surgery visualization system includes an image sensor and contains an imaging system for producing an image of an object region with an optical imaging beam path in an imaging plane on an image sensor. A computer unit has an image processing routine for an image of the object region, the image having been captured by the image sensor. An image display unit visualizes image data of an image processed in the computer unit. An ophthalmoscopy loupe of the system images a portion lying within a patient's eye in an intermediate image plane that is conjugate to the imaging plane on the image sensor. The image processing routine separates the first portions of the image of the object region from second portions of the image of the object region in the imaging plane on the image sensor.

Abstract: A wide field fundus camera is disclosed to implement multiple illumination beam projectors and to capture multiple retinal images at a various viewing angles to mimic wide field retinal examination with an indirect ophthalmoscope. The wide field fundus camera may incorporate a consumer image recording device with fast auto focusing so as to make the device quick to respond and easy to use. The wide field fundus camera may include narrow and broad slit beam illuminations to enhance autofocusing and imaging through less transparent crystalline lens and through haze due to Purkinje reflections from crystalline lens surfaces. Control of multiple illumination beam projectors in a programmable manner can be used to assess alignment of each illumination beam projector with the eye and to capture said multiple retinal images. Furthermore, a method is disclosed to montage said multiple retinal images into a single montage and to remove haze and reflections.

Abstract: Methods for improved acquisition and processing of optical coherence tomography (OCT) angiography data are presented. One embodiment involves improving the acquisition of the data by evaluating the quality of different portions of the data to identify sections having non-uniform acquisition parameters or non-uniformities due to opacities in the eye such as floaters. The identified sections can then be brought to the attention of the user or automatically reacquired. In another embodiment, segmentation of layers in the retina includes both structural and flow information derived from motion contrast processing. In a further embodiment, the health of the eye is evaluating by comparing a metric reflecting the density of vessels at a particular location in the eye determined by OCT angiography to a database of values calculated on normal eyes.

Abstract: An ophthalmologic apparatus according to the embodiments includes an OCT optical system, an alignment unit, an image forming unit, a first calculator, and a second calculator. The OCT optical system is configured to acquire OCT data of a fundus of a subject's eye by projecting measurement light onto the fundus. The alignment unit is configured to perform alignment of the OCT optical system with reference to a predetermined site of the subject's eye. The image forming unit is configured to form a tomographic image of the fundus based on the OCT data acquired by the OCT optical system which has been aligned by the alignment unit. The first calculator is configured to calculate a first tilt angle of the tomographic image. The second calculator is configured to calculate a second tilt angle of the fundus by correcting the first tilt angle based on alignment result of the OCT optical system with respect to the predetermined site by the alignment unit.

Abstract: An optical imaging system for an ophthalmic laser beam delivery system, which includes a focusing objective including a plurality of lenses, a semi-transparent folding mirror disposed near an entrance of the focusing objective for reflecting a treatment laser beam into the focusing objective, a prism disposed adjacent a back surface of the folding mirror, the prism having a first, a second and a third surface, the second surface being disposed adjacent the back surface of the folding mirror, the prism being configured to reflect a light that has entered the second surface sequentially by the first surface and by the second surface toward the third surface to be output, a focusing lens module disposed adjacent the third surface of the prism to focus light output from the third surface of the prism, and an image sensor disposed to receive the light focused by the focusing lens module to form an image.

Abstract: An imaging system includes an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The eye interface device interfaces with an eye. The scanning assembly supports the eye interface device and scans a focal point of an electromagnetic radiation beam within the eye. The beam source generates the electromagnetic radiation beam. The free-floating mechanism supports the scanning assembly and accommodates movement of the eye and provides a variable optical path for the electronic radiation beam and a portion of the electronic radiation beam reflected from the focal point location. The variable optical path is disposed between the beam source and the scanner and has an optical path length that varies to accommodate movement of the eye. The detection assembly generates a signal indicative of intensity of a portion of the electromagnetic radiation beam reflected from the focal point location.

Abstract: An imaging device may include first and second optical channels, where each of the first and second optical channels include a discrete optical imaging pathway. The first and second optical channels may be aimed at different angles relative to each other, and each may be directed towards corresponding partially overlapping zones of an object for imaging. Each of the optical channels may include an illuminating source configured to be turned on or off, where illumination from the illuminating sources follow respective illumination paths to the object. Each of the optical channels may additionally include lenses shared by both the respective optical imaging pathways and the respective illumination paths, and each may include an image sensor. The imaging device may also include a computing device configured to turn on the illuminating source of the first optical channel while capturing an image using the image sensor of the second optical channel.

Abstract: An ophthalmic apparatus that may include a processor; and a memory storing computer-readable instructions therein, the computer-readable instructions, when executed by the processor, causing the ophthalmic apparatus to perform: acquiring a two-dimensional tomographic image of the subjected eye; calculating a preoperative shape of the subjected eye based on a preoperative two-dimensional tomographic image of a preoperative subjected eye acquired by the acquiring of the two-dimensional tomographic image; calculating a postoperative shape of the subjected eye based on a postoperative two-dimensional tomographic image of a postoperative subjected eye acquired by the acquiring of the two-dimensional tomographic image; and calculating a displacement amount between a first reference axis obtained from the preoperative two-dimensional tomographic image of the preoperative subjected eye and a second reference axis obtained from the postoperative two-dimensional tomographic image of the postoperative subjected eye, bas

Abstract: A head-mounted display (HMD) presents content for viewing by users. The HMD includes a display element for displaying content to a user wearing the HMD and a detector (e.g., camera) for capturing one or more images of a retina of an eye of the user, where the one or more images are captured while the retina is reflecting light originating from one or more tracking light sources positioned at predetermined locations. The HMD also includes a controller for identifying one or more features of the retina based on the captured one or more images of the retina and for determining one or more optical metrics based in part on the identified one or more features of the retina.

Abstract: An ophthalmoscope having a laser device for laser irradiation of an eye, in particular for performing a photocoagulation on fundus of the eye of the eye, includes an illuminator for illuminating the eye as well as a camera for acquiring an image of the eye. The illuminator is adapted to generate visible and infrared lights. The ophthalmoscope further includes a control unit adapted to trigger the illuminator for generating a light pulse of visible light and to read out from the camera a control image of the eye acquired by the camera during the light pulse. The ophthalmoscope is configurable to acquire an image of an eye and perform a laser treatment of an eye.

Abstract: Provided is an image pickup apparatus including a light beam projecting unit projecting a light beam onto an eye to be inspected, an image signal acquiring unit acquiring an image signal based on the light beam reflected by the eye, a scanning unit included in the light beam projecting unit and scanning the eye with the light beam, an image generating unit generating an image based on the acquired image signal, a position information generating unit arranged outside an optical path of projecting the light beam onto the eye by the light beam projecting unit, a control unit causing the scanning unit to scan the position information generating unit with the light beam, and a correcting unit correcting timing of acquiring the image signal by the image signal acquiring unit based on position information acquired from the light beam with which the position information generating unit is scanned.

Abstract: An ophthalmologic apparatus according to an exemplary embodiment acquires data by OCT scanning of the anterior eye segment. The apparatus generates distribution information of a predetermined parameter in the anterior eye segment by analyzing the data. The apparatus acquires a front image of the anterior eye segment at the time of the data being acquired. The apparatus stores the first distribution information and the first front image both corresponding to the first time, and the second distribution information and the second front image both corresponding to the second time. The apparatus calculates the positional difference between the first front image and the second front image. The apparatus applies registration to the first distribution information and the second distribution information based on the positional difference.

Abstract: An apparatus for imaging an interior of an eye includes a light sensitive sensor, and a housing structure with an opening defining an imaging area to place the eye for imaging by the light sensitive sensor. One or more light emitters (LEs) are disposed in an image path between the light sensitive sensor and the eye during capture of a plurality of images. A controller is coupled to the plurality of LEs and the light sensitive sensor. The controller implements logic that when executed by the controller causes the apparatus to perform operations including: illuminating the imaging area with the one or more LEs; and capturing, with the light sensitive sensor, the plurality of images of the interior of the eye at the same time as the eye is illuminated with the light from the one or more LEs.

Abstract: A fundus camera includes an eyeball-offset detection device and an annular illumination device. The eyeball-offset detection device is configured to detect an offset vector of a lens of the fundus camera relative to an inspected eyeball. The annular illumination device includes a plurality of illumination elements that are arranged in a ring shape around an optical axis of an imaging system of the fundus camera. According to the offset vector of the lens relative to the inspected eyeball, the fundus camera selectively activates one or more illumination elements at corresponding positions to keep an illumination optical path away from a center area of the pupil of the inspected eyeball to reduce effects of corneal reflection and improve illumination quality. Therefore, the abovementioned fundus camera has a large operable range.

Abstract: An apparatus is described. The apparatus includes a camera comprising a beam splitter to impose different optical paths for visible light and infra red light received by the camera. The camera also includes an infra red light detector to detect the infra red light and a visible light detector to detect the visible light, wherein, the different optical paths include an optical path having more than one internal reflection within the beam splitter.

Abstract: An eyeball tracking method and apparatus, and a device. The method comprises: acquiring a facial grey-scale image set to be detected (101); judging whether the contour of an eyeball iris is determined in an N-th frame facial grey-scale image in the facial grey-scale image set to be detected (102); if not, detecting an eyeball pupil in the N-th frame facial grey-scale image, and determining the central position of the eyeball pupil in the N-th frame facial grey-scale image (103); in the N-th frame facial grey-scale image, taking the central position of the eyeball pupil as a centre to determine a grey-scale image region corresponding to an eyeball window (104); and according to the grey-scale image region corresponding to the eyeball window, determining the contour of the eyeball iris in the N-th frame facial grey-scale image (105).

Abstract: The present invention discloses a hand-held autonomous visual acuity measurement apparatus and a visual acuity measuring method. The invention comprises a corneal curvature measurement module comprising a first light source for emitting a first light beam and a first image collector for collecting an image formed from the first light beam after it has been reflected by cornea, the first image collector being movably provided in the corneal curvature measurement optical path of the corneal curvature measurement module, and the corneal curvature measurement module further comprises a first motor for driving the first image collector to move along the corneal curvature measurement optical path so that the first image collector moves to the imaging position.

Abstract: Systems and methods for imaging an eye are disclosed. The systems and methods may include at least one plenoptic camera. The systems and methods may include an illumination source with a plurality of lights.

Abstract: A tomographic-image pickup unit is controlled so as to capture a tomographic image in response to a signal input from a signal input unit. Then, a display unit is controlled so as to display the captured tomographic image. An eyeground-image pickup unit is controlled so as to capture a two-dimensional image in response to a signal input from the signal input unit while the tomographic image is displayed on the display unit. Therewith, the user can more easily perform imaging, and the time load on the subject is reduced.

Abstract: A computerized device for processing image data is proposed. The computerized device comprises a receiving unit a receiving unit which is configured to receive optical coherence tomography data of a tissue of a patient, in particular of a retina, a providing unit which is configured to provide a prediction model for processing the optical coherence tomography data, and a processing unit which is configured to process the received optical coherence tomography data using the prediction model for providing at least one prediction parameter for predicting prospective objects of the tissue and/or prospective features allocated to the tissue.

Abstract: The present disclosure relates to an apparatus for angiographic optical coherence tomography in the retina or the choroid, and a method for diagnosing diseases by using the same and, more specifically, to: an apparatus for angiographic optical coherence tomography in the retina and the choroid, capable of diagnosing, at an early stage, shock states or diseases such as those of sepsis by quickly and objectively recognizing the low perfusion of tissue; and a diagnostic method using the same.

Abstract: An ophthalmic image processing apparatus that processes pieces of image data of a subject eye which are acquired by a plurality of ophthalmic examination apparatuses including a first ophthalmic examination apparatus obtaining first image data of the subject eye and a second ophthalmic examination apparatus obtaining second image data of the subject eye includes: a processor; and memory storing computer readable instructions, when executed by the processor, causing the ophthalmic image processing apparatus to execute: setting process of setting image types for the first image data and the second image data that form a registration image; and image processing process of generating the registration image in which the first image data and the second image data which correspond to the image types set in the setting process are superimposed on each other, and outputting the generated registration image.

Abstract: An example eye fundus imaging apparatus can include: a display device; an image capture device configured to capture at least one image of a fundus of an eye; and a control module programmed to: display a target, the target indicating a desired position for the image capture device to capture the at least one image of the fundus of the eye; monitor a relative position of the eye with respect to the target; and when the relative position of the eye corresponds to the target, automatically capture the at least one image of the fundus of the eye.

Abstract: To obtain an imaging device capable of achieving high functionality of the imaging device by facilitating detection of an incident angle of light transmitted through a grating substrate.