Abstract: A lighting device that is capable of retracting a reflective member inside a lighting device and of deciding size of the reflective member irrespective of the size of the lighting device. The lighting device includes a light emitting section and a reflective member. The reflective member is drawably retracted in the light emitting section and is provided with reflectors that are developed by a drawing operation to reflect a part of light irradiated from the light emitting section. Area of the reflectors in a developed state is more than area of the reflectors in a retracted state.

Abstract: Systems and methods are provided for evaluating the complexity of a stenosis or a section of a vessel. At least one image of the stenosis or the section of the vessel is provided. A geometrical feature value of the stenosis and/or or the section of the vessel is identified from the at least one image. At least one intensity feature value is determined based on a grey level intensity of the stenosis or the section of the vessel from the at least one image. A complexity value relating to the geometrical complexity of the stenosis or the section of the vessel is calculated as a function of the at least one geometrical feature value and the at least one intensity feature value of the stenosis or the section of the vessel.

Abstract: A method of providing diagnosis information includes acquiring, from a first imaging area of an eye to be inspected, a first set of signals to create three-dimensional tomographic data, acquiring, from a second imaging area including at least a part of the first imaging area, a second set of signals to create three-dimensional motion contrast data, generating a first display image of the eye to be inspected using the first set of signals, generating a second display image using the second set of signals, and changing, when the first display image and the second display image are displayed side by side, at least one of display magnifications, lateral display positions of the eye to be inspected, a display range in the depth direction of the eye to be inspected, and viewpoints for a three-dimensional display, for the first display image and the second display image correspondingly.

Abstract: Systems and methods for eye tracking for motion corrected ophthalmic optical coherence tomography (OCT) are disclosed. According to an aspect, an imaging system includes an eye tracking device configured to determine movement of an eye. The imaging system also includes an OCT apparatus configured to generate OCT images of a retina of the eye. The OCT apparatus includes a scanner operable to be moved for relocating an OCT scan pivot at a pupil plane for image capture and during capture of the OCT images. The imaging system also includes a controller configured to control the scanner to relocate the OCT scan pivot at the pupil plane based on the determined movement of the eye.

Abstract: A drowsiness detection apparatus includes a camera that images a face of a user, an opening/closing-degree calculation unit that calculates an eyelid opening/closing degree based on a face image acquired by the imaging, a face-angle detection unit that detects a face angle based on the face image, a distance calculation unit that calculates the distance between an eyelid and an eyebrow based on the face image, an opening/closing-degree correction unit that corrects the eyelid opening/closing degree based on the detected face angle and the calculated distance between the eyelid and eyebrow, and an eyelid-opening/closing determination unit that determines whether the eyelids are opened or closed by comparing the eyelid opening/closing degree with a predetermined threshold value.

Abstract: An optical coherence tomography (OCT) system for imaging a retina applies a user specific focus correction to focus a sample arm light beam on the user's retina. An OCT image detector generates an OCT signal. A control unit monitors the OCT signal, controls a reference arm optical path length adjustment mechanism to identify a length of the reference arm optical path for which the OCT signal corresponds to an OCT image of the retina, and varies an operational parameter of the sample arm light beam focus mechanism over a range, while maintaining the length of the reference arm optical path for which the OCT signal corresponds to the OCT image of the retina, to identify a focus correction for the user, based on the OCT signal, for application to the sample arm light beam.

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.

Abstract: A probability distribution of visual sensitivities at each visual target presentation position of the subject is inferred on the basis of the test result information which is visual sensitivity information at each of the visual target presentation positions obtained through the tests performed in the past. Input of visual sensitivity information of the subject at at least one presentation position among the plurality of visual target presentation positions is received. Mutual information between visual sensitivity information of the subject regarding the visual test target represented by the received information and visual sensitivity information regarding each visual test target for which no visual sensitivity information of subject has been input, using the inferred probability distribution, is calculated, and the calculated mutual information is provided for a predetermined process for selecting a position at which the next visual test target is to be presented.

Abstract: Embodiments of the present invention provide an optical system (100) for imaging a retina through a pupil of an eye (10). The optical system (100) comprises an illumination source (120) for providing light to illuminate the eye (10) via an illumination optical system (140). The optical system further comprises an imaging device (130) for outputting image data corresponding to the retina of the eye (10) over a period of time. Said imaging device (130) is arranged to receive reflected light from the eye (10) via an imaging optical system (150). The optical system (100) further comprises a moveably mounted offner relay (110) arranged to direct light received from the illumination optical system (140) to the eye (10) and to direct reflected light from the eye (10) to the imaging optical system (150). Said offner relay (110) is arranged to move to track a location of the pupil.

Abstract: Provided is a snapshot spectral domain optical coherence tomographer comprising a light source providing a plurality of beamlets; a beam splitter, splitting the plurality of beamlets into a reference arm and a sample arm; a first optical system that projects the sample arm onto multiple locations of a sample; a second optical system for collection of a plurality of reflected sample beamlets; a third optical system projecting the reference arm to a reflecting surface and receiving a plurality of reflected reference beamlets; a parallel interferometer that provides a plurality of interferograms from each of the plurality of sample beamlets with each of the plurality of reference beamlets; an optical image mapper configured to spatially separate the plurality of interferograms; a spectrometer configured to disperse each of the interferograms into its respective spectral components and project each interferogram in parallel; and a photodetector providing photon quantification.

Abstract: The present technology relates to an information processing device and an information processing method for enabling continuous measurement of information in a body. The information processing device includes a light emitting unit that emits light of a predetermined wavelength, an imaging unit that captures reflected light from an object, an analysis unit that analyzes an image captured by the imaging unit, a storage unit that stores an analysis result analyzed by the analysis unit, a communication unit that transmits the analysis result stored in the storage unit to another device, and a battery unit that generates and stores power to supply electric power to each unit, and the information processing device is embedded in a body to operate. The light emitting unit emits beams of light of different wavelengths.

Abstract: The present disclosure provides a system and method for monitoring phototoxicity caused by vitreous visualization device (“VVD”) illumination during ophthalmic surgery. The systems and methods determine the cumulative amount of optical energy incident on the retina, which corresponds to phototoxicity, the distance between a cutter of the VVD and the retina, and areas where the vitreous has been removed, or any combination thereof. The disclosure further provides a method for monitoring and preventing phototoxicity caused by VVD illumination during ophthalmic surgery. The method may further include determining the distance between a cutter of the VVD and the retina, and determining areas where the vitreous has been removed based on focus areas of the retina that the plurality of light spots has contacted.

Abstract: Apparatus and methods of non-mydriatic fundus imaging are disclosed. Fundus imaging apparatus include an infrared light unit configured to illuminate during a fundus scan. Based on fundus scanning, a first focus position is determined. Fundus images are then captured starting at the first focus position. Focus of the fundus imaging apparatus is adjusted to a plurality of sequential diopters and images captured at each adjustment.

Abstract: An adaptor for attachment to an image acquisition device, the image acquisition device having one or more camera apertures for enabling capture of one or more images entering the image acquisition device via the one or more camera apertures. The adaptor has a housing defining a passage along which light waves may travel, an objective lens arrangement within the passage, a secondary lens arrangement within the passage positioned such that, when the adaptor is attached to an image acquisition device, the secondary lens arrangement is along a possible light pathway between the objective lens arrangement and one or more camera apertures. The lens arrangements are together configured to magnify an image of a pupil of the eye in proximity to a plane of one or more camera apertures and to focus light waves from a light source at a point external of the adaptor and offset from the optical axis of the objective lens.

Abstract: A method and a circuit for modulating an eye diagram amplitude, a method and a circuitry for data transmission, and a display device are provided. The method for modulating an eye diagram amplitude includes: an eye diagram amplitude setting step, including: setting, by a base eye diagram amplitude setting unit, a base eye diagram amplitude for a source driver; a preset differential signal outputting step, including: outputting, by a preset differential signal outputting unit, a preset differential signal to the source driver; a comparing step, including: comparing, by a comparing unit, a differential signal received by the source driver and the preset differential signal to obtain a comparison result; and a modulating step, including: modulating, by an eye diagram amplitude modulating unit, an eye diagram amplitude of the source driver based on the comparison result.

Abstract: A diagnosis support apparatus comprises an acquiring unit that acquires a plurality of examination data items having different examination dates, a setting unit that sets an extraction condition for examination data items, an extracting unit that extracts, from the plurality of acquired examination data items, examination data items corresponding to the set extraction condition, and a displaying unit that arranges and displays the extracted examination data items, wherein the setting unit sets the extraction condition based on an interval between examination dates of examination data items.

Abstract: Ocular surface interferometry devices, systems, and methods are disclosed for imaging an ocular tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image, wherein the specularly reflected light may be produced from various portions of the ocular tear film by obliquely illuminating various portions of the ocular tear film with a multi-wavelength light source, such as in a tiling pattern(s). The imaging device can also be focused on the lipid layer to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image, which can used to measure a tear film layer thickness.

Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including the lipid layer thickness (LLT) and/or the aqueous layer thickness (ALT). The TFLT can be used to diagnose dry eye syndrome (DES). Certain embodiments also include ocular topography devices, systems and methods for deducing corneal shape by capturing an image of a target reflecting from the surface of the cornea. The image of the target contains topography information that is reviewable by a clinician to diagnose the health of the patient's eye by detecting corneal aberrations and/or abnormalities in corneal shape. Certain embodiments also include a combination of the OSI and ocular topography devices, systems and methods to provide imaging that can be used to yield a combined diagnosis of the patient's tear film and corneal shape.

Abstract: An ultra wide field fundus imaging system comprises a photosource, an optical splitter, a scanning assembly, a curved reflector, a probe pinhole and an imaging assembly. The scanning assembly includes a first scanning mirror scanning along a first direction and a second scanning mirror scanning along a second direction. The light emitted by the photosource passes through the optical splitter, then successively is reflected by the first scanning mirror, the curved reflector, the second scanning mirror and the curved reflector, and then enters in the fundus; the light entering the fundus is reflected by the retina and then successively is reflected by the curved reflector, the second scanning mirror, the curved reflector, the first scanning mirror and then returned to the optical splitter; the light is reflected by the optical splitter and passes through the probe pinhole, finally the light enters in the imaging assembly.

Abstract: Methods and apparatus are presented for obtaining high-resolution 3-D images of a sample over a range of wavelengths, optionally with polarisation-sensitive detection. In preferred embodiments a spectral domain OCT apparatus is used to sample the complex field of light reflected or scattered from a sample, providing full range imaging. In certain embodiments structured illumination is utilised to provide enhanced lateral resolution. In certain embodiments the resolution or depth of field of images is enhanced by digital refocusing or digital correction of aberrations in the sample. Individual sample volumes are imaged using single shot techniques, and larger volumes can be imaged by stitching together images of adjacent volumes.

Abstract: A confocal laser fundus angiographic device, comprises: an objective lens, a scanning lens, a scanning galvanometer, a mirror, a filtering module, an imaging detection assembly and an excitation light source. The illumination light emitted by the excitation light source enters the fundus passing through the scanning galvanometer, the scanning lens and the objective lens. Fluorescent substances in fundus vessels are excited by the illumination light and emit light with a specific wavelength. The light with a specific wavelength enters the imaging detection assembly by passing through the objective lens, the scanning lens, the scanning galvanometer, the mirror and the filtering module. The filtering module comprises a base, a motor mounted on the base, a rotary block mounted on the motor and at least one filter mounted on the rotary block. The base is provided with a light-through hole.

Abstract: Disclosed is a process and device that enables ultra-high resolution one- and two-dimensional spatial imaging of Rayleigh, Raman and Thomson spectral features without the need for a spectrometer. The disclosed approach provides the capability for imaging of a single spectral feature such as a single rotational Raman line and the simultaneous elimination of background scattering, or for separating the rotational Raman image from the Rayleigh scattering. High collection efficiency provides the opportunity for single pulse time frozen images to be acquired.

Abstract: An ophthalmologic imaging apparatus includes a housing configured to include an optical system that irradiates a subject's eye with measurement light and receives returning light returned from the subject's eye irradiated with the measurement light, a rotation unit configured to rotate the housing by making a predetermined position on an optical axis of the optical system as a rotation center, a position changing unit configured to change a position of the rotation center on the optical axis of the optical system, and a holding unit configured to hold a positional relationship between the housing and the subject's eye when the position of the rotation center on the optical axis of the optical system is changed.

Abstract: Modular lens adapter system are provided for use with a hand held computer device having a camera for mobile ophthalmoscopy. The modular lens adapter systems include an anterior adapter and a posterior adapter configured to removably engage with a hand held computer device. The anterior adapter can include a variable intensity light source, a clamp, and a movable macro lens. The posterior adapter can include a hand held computer device mount, a lens mount, and a telescoping arm with a first end and a second end with the first end configured to removably engage with the mount and the second end configured to contact the lens mount. Methods are also provided for using the systems to obtain an image of an anterior portion of the patient's eye and a posterior portion of the patient's eye.

Abstract: Laser assisted cataract surgery methods and devices utilize one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may be applied to the anterior lens capsule to facilitate laser thermal separation of tissue along a treatment beam path on the lens capsule. Relative or absolute reflectance from the eye, and optionally from a surgical contact lens, may be measured to confirm and optionally quantify the presence of the light absorbing agent, before the treatment beam is applied.

Abstract: A macular health measurement and storage system comprises a plurality of macular-pigment measurement machine for measuring macular pigment density in humans, a plurality of computers each of which is associated with a corresponding one the macular-pigment measuring machines, and a central host. The plurality of macular-pigment measurement machines include a device for receiving macular pigment data from a patient, at least one data transfer port, and at least one processor that enables the transfer of the macular pigment data from the transfer port. The plurality of computers include a first port coupled to the data transfer port of the corresponding macular-pigment measurement machine for receiving the macular pigment data. Each of the computers includes a second port for transferring patient data. The central host is coupled to the second ports on each of the plurality of computers. The central host includes a storage device for storing the patient data.

Abstract: An inspection apparatus includes: a first scanning member scanning an object by reciprocating illumination light in a main scanning direction; a second scanning member scanning the object at a constant speed in a sub-scanning direction; a scanning control unit allowing the first and second scanning members to perform 2D scans of the object with the illumination light in first and second fields within a data acquisition area; and a data acquisition unit acquiring data based on the illumination light returned from the first and second fields. The scanning control unit sets the second field by shifting the first field by a predetermined amount in the sub-scanning direction, the predetermined amount determined such that the closer to the scanning center in the main scanning direction within the data acquisition area, the more regular the interval between the first and second fields in the sub-scanning direction.

Abstract: Navigation systems and methods for tracking physical objects near a target site during a surgical procedure. The navigation system comprises a robotic device and an instrument attached to the robotic device. A vision device is attached to the robotic device or the instrument and generates vision data sets. The vision data sets are captured from multiple perspectives of the physical object. A computing system associates a virtual object with the physical object based on one or more features of the physical object identifiable in the vision data sets. The virtual object at least partially defines a virtual boundary for the instrument.

Abstract: A handheld molecular imaging navigation system comprises a multi-spectral light source module configured to provide light in a plurality of different spectrum bands in a time division control manner according to a control signal sequence to irradiate an inspected object; a time division control module configured to generate the control signal sequence; an optical signal acquisition module configured to acquire a near-infrared fluorescence image and a visible light image of the inspected object in a time division control manner according to the control signal sequence provided by the time division control module; and a processing module configured to perform image processing on the acquired near-infrared fluorescence image and visible light image according to the control signal sequence to fuse the visible light image and the fluorescence image and output the fused image, and output a feedback signal according to the acquired near-infrared fluorescence image and visible light image.

Abstract: A system for performing measurements of an eye comprises: a measurement tool that measures the eye, at least one rest that maintains a facial measurement position and defines a centering rest portion that maintains a lateral facial measurement position; an adjuster mechanism that moves an objective of the measurement tool relative to the eye; and a processing unit configured to control the system. The unit controls the system to position, for a first eye, the objective at a predefined first pre-scan position; scan the objective away from the first pre-scan position until the system detects a pupil of the first eye; and trigger one or more measurements of the first eye dependent on the system detecting the pupil of the first eye.

Abstract: The invention relates to an apparatus and a method therewith to quantify visual field in infants. The invention provides a novel solution to the unmet need of detection of defects in the visual field in infants and/or babies and providing an apparatus with a software framework to minimize the errors of recording the readings and increasing their precision and analyzing said results automatically using the software embedded in the system. Said apparatus to quantify visual field in infants comprise of a light projection device onto a dome-shaped hemispherical structure with an infra-red camera along with fixation lights, a means for monitoring responses of the subject during testing, a means for recording and analyzing the readings. Said means to detect and record the eye/head movement in the subject during testing comprises said infra red (IR) camera connected to a device wherein software application is embedded.

Abstract: The present disclosure relates to a system and method for verifying a diopter setting and range of an optical system eyepiece by utilizing an image sensor to view and analyze test patterns of spots displayed within the optical system eyepiece and calculating the diopter setting and range of the optical system eyepiece from an observed change in the test pattern at different diopter settings.

Abstract: A vision-compensating device allowing observation along an optical axis of observation with an optical correction of variable power includes a lens having, along the optical axis, a spherical power that is variable as a function of a first control, and an optical assembly generating, along the optical axis, a cylindrical correction that is variable as a function of at least one second control applied to the optical assembly. The vision-compensating device also includes a module for receiving at least one setpoint for the optical correction and a module for determining the first control and the second control depending on the setpoint by way of a mode taking into account the distance separating the lens and the optical assembly. A method for controlling a vision-compensating device and a binocular optometry device are also proposed.

Abstract: Ocular fundus inspection apparatus (10) having a frame (11) provided with references for the positioning of at least one of the patient's eyes in an inspection position, and an inspection unit (100) fixed to the frame (11) and comprising: a first optical unit (12) having an optical axis incident in correspondence of the inspection position references; an image detecting device (13); a second optical unit (14), for the focusing, having an optical axis incident on the detecting device (13), in said inspection unit (100) being defined an optical path between the first optical unit (12) and the detecting device (13); a first lighting unit (15) for projecting a focusing pattern, for focusing the ocular fundus on said detecting device (13), the focusing pattern being formed by an infrared radiation. The first lighting unit (15) emits the focusing pattern from a first emission position.

Abstract: Portable fundus cameras and portable fundus camera modules are disclosed. In one embodiment, a portable fundus camera module comprises a housing having a first aperture and a second aperture formed therethrough, and a plurality of optical components disposed within the housing. The plurality of optical components are arranged to direct light generated by a light source through the first aperture via a first optical channel and to a retina of a patient when the retina is located adjacent to the first aperture; direct reflected light from the retina into the housing through the first aperture and to a light detector via a second optical channel when the fundus camera module is mechanically coupled to a mobile device.

Abstract: Systems, methods, and computer readable media to detect and track a user's eye gaze and head movement are described. In general, techniques are disclosed for identifying a user's pupil location and using this information, in conjunction with a three dimensional (3D) model of the user's head, perform gaze tracking operations. More particularly, techniques disclosed herein utilize pupil gradient information to refine an initial pupil location estimate. Once identified, the pupil's location may be combined with 3D head pose information to generate an accurate and robust gaze detection mechanism.

Abstract: The subject invention provides novel apparatuses and methods for assessing the structure and function of photoreceptors in retina. In a specific embodiment, the assessment is accomplished by imaging rhodopsin, pigmented protein responsible for initiating vision acquisition of the eye, in living subjects. Advantageously, the technologies provided herein can be used for clinical evaluation of retinal photoreceptors for diagnosis, disease staging and follow-up, and outcome measurement for clinical trials of retinal degenerative disorders, including, for example, hereditary retinal degeneration and age-related macular degeneration.

Abstract: An image processing system includes: an analysis unit configured to obtain information indicating a degree of curvature of a retina from a tomographic image of an eye to be examined; and an obtaining unit configured to obtain a category of the eye to be examined based on an analysis result.

Abstract: Disclosed is an optometry apparatus capable of measuring para-central defocus, comprising a diopter measurement module. The diopter measurement module comprises a first light source (1) emitting a first light beam. The optometry apparatus also comprises a scanning module for adjusting the position of a light spot formed on the retina by the first light beam. The scanning module comprises a first reflecting mirror (3) and a second reflecting mirror (5) rotatably positioned in sequence in the emergent optical path of the first light source (1). The rotation axis of the first reflecting mirror (3) and the rotation axis of the second reflecting mirror (5) form therebetween an angle greater than 0 degree and less than 180 degrees.

Abstract: Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Abstract: An eyepiece waveguide for an augmented reality. The eyepiece waveguide can include a transparent substrate with an input coupler region, first and second orthogonal pupil expander (OPE) regions, and an exit pupil expander (EPE) region. The input coupler region can be positioned between the first and second OPE regions and can divide and re-direct an input light beam that is externally incident on the input coupler region into first and second guided light beams that propagate inside the substrate, with the first guided beam being directed toward the first OPE region and the second guided beam being directed toward the second OPE region. The first and second OPE regions can respectively divide the first and second guided beams into a plurality of replicated, spaced-apart beams. The EPE region can re-direct the replicated beams from both the first and second OPE regions such that they exit the substrate.

Abstract: Methods and systems for anti-parallax correction of stereoscopic surgical images may employ a stereoscopic surgical microscope to generate overlay content as left and right digital images that are overlaid on respective left and right analog images from an objective field of view of the surgical microscope. The user may select a location-dependent feature in the overlay content and may select left or right for the anti-parallax correction.

Abstract: Systems and methods for Broad Line Fundus Imaging (BLFI), an imaging approach that is a hybrid between confocal and widefield imaging systems, are presented. These systems and methods are focused on improving the quality and signal of broad line fundus images or imaging methods to create high contrast and high resolution fundus images. Embodiments related to improved pupil splitting, artifact removal, reflex minimization, adaptable field of view, instrument alignment and illumination details are considered.

Abstract: A method and system for correction of decorrelation tail artifacts in optical coherence tomography (OCT) angiography volumetric data defines a movable target subvolume within the OCT-A volumetric data. The target subvolume is axially moveable within the OCT-A volumetric data in discrete axial steps. At each axial step, a reference subvolume corresponding to a depth location in the OCT A volumetric data is defined axially offset from the target subvolume. The reference subvolume may be defined within the OCT A volumetric data, or defined within a different (previously corrected) OCT-A volume. Irrespective, corrected OCT-A data that corrects for decorrelation tail artifacts in the target subvolume is defined using information in the reference subvolume and information in the target subvolume.

Abstract: An optical coherence tomography (OCT) system combining multiple wavelengths is generally described. In an example, the OCT system includes a first light source configured to emit a first beam having a first wavelength. The OCT system further includes a second light source configured to emit a second beam having a second wavelength. The OCT system further includes an interferometer. The first beam and the second beam are configured to be directed into the interferometer. The interferometer includes a reference path and an interferometer sample path. The OCT system further includes a first beam splitter configured to divide, from an output of the interferometer sample path the first beam into a first sample path, and the second beam into a second sample path. The OCT system further includes a second beam splitter configured to combine the first beam and the second beam into a common axis.

Abstract: Methods and systems for performing an ophthalmic surgical procedure include pulsed illumination of target tissue. The systems may include an illumination instrument arranged to illuminate tissue at a surgical site during the ophthalmic surgical procedure. A light source provides illumination to the illumination instrument for emission from the illumination instrument toward the surgical site. A controller communicates with the light source and activates the light source to provide illumination pulses at a frequency above the flickering perception in humans and with enough light for cameral exposure and human light perception. The light source pulses to minimize phototoxicity.

Abstract: An ocular fundus camera system and an associated methodology. The system includes (a) an image sensor disposed along a fundus-image reflection path adjacent that path's downstream end, and in optical communication with light carried in this path, (b) an aperture centered on the reflection path's long axis, operatively associated with, and stationary with respect to, the sensor at a location which is upstream from the sensor, and (c), for accomplishing (1) precision fundus-image focusing on the sensor, and additionally (2) autorefraction, optical, light-content shifting structure, operable selectively for producing, within that portion of the reflection path which is disposed downstream from the shifting structure, relative trans-axial displacement solely of any non-collimated light carried in that portion of the main path which is disposed upstream from the shifting structure.

Abstract: Embodiments disclosed herein include devices, systems, and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms. The apparatus and methods for determining tear film break-up time and for detecting eyelid margin contact and blink rates, particularly for diagnosing, measuring, and/or analyzing dry eye conditions and symptoms may employ ocular surface interferometry (OSI) devices or other imaging and display devices capable of imaging and displaying a picture of a patient's eye during tear film break-up time and blink rate related procedures.

Abstract: Systems and methods of obtaining and recording fundus images by minimally trained persons, which includes a camera for obtaining images of a fundus of a subject's eye, in combination with mathematical methods to assign real time image quality classification to the images obtained based upon a set of criteria. The classified images will be further processed if the classified images are of sufficient image quality for clinical interpretation by machine-coded and/or human-based methods. Such systems and methods can thus automatically determine whether the quality of a retinal image is sufficient for computer-based eye disease screening. The system integrates global histogram features, textural features, and vessel density, as well as a local non-reference perceptual sharpness metric. A partial least square (PLS) classifier is trained to distinguish low quality images from normal quality images.

Abstract: Through the present invention, a perimetry result is obtained for a position on a retina surface designated as a position to be tested. As illustrated in the drawing, “the position of a ganglion cell (RGC)” and “the position of a photoreceptor cell (C) for sending information to the ganglion cell (RGC)” are offset on the retina surface (macular part). Here, when position (P1) is designated as a test position for testing the functioning of a ganglion cell at position (P1), the perimeter of the present invention finds “the position (P2) of the photoreceptor cell for sending information to the ganglion cell at position (P1),” presents a visual target at position (P2) rather than position (P1), and tests a visual field. The information of the visual target is sent to the ganglion cell at position (P1), and the functioning of the ganglion cell can therefore be tested.