Abstract: The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metabolites), dopamine, dopamine metabolites, serotonin, serotonin metabolites, or fasting triglycerides, wherein one or more of: (a) NE metabolites, (b) NE/NE metabolites: dopamine/dopamine metabolites, (c) NE and serotonin, (d) NE/NE metabolites and serotonin, (e) NE and serotonin metabolites, (f) NE/NE metabolites and serotonin metabolites, or (g) NE is/are greater than about 30% over normal level; or dopamine/dopamine metabolites are less than about 30% below normal; or fasting triglycerides are greater than about 150 mg/dl and/or said patient has hypertension. The present invention is also directed to treating identified patients with dopamine agonist therapy.

Abstract: The invention is based on methods that allow analysis of mixed meningococcal saccharides from multiple serogroups even though they share monosaccharide units. With a combination of saccharides from serogroups C, W135 and Y, the invention analyses sialic acid, glucose and galactose content. The glucose and galactose results are used to directly quantify saccharides from serogroups Y and W135, respectively, and the combined glucose and galactose content is subtracted from the sialic acid content to quantify saccharides from serogroup C. The three serogroups can thus be resolved even though their monosaccharide contents overlap. The three different monosaccharide analyses can be performed on the same material, without interference between the monosaccharides and without interference from any other saccharide materials in the composition (e.g. lyophilisation stabilisers).

Abstract: Systems comprising an optical fiber switch connected to a light source and an optical fiber probe, the optical fiber probe comprising a first optical fiber connected to the optical fiber switch and a second optical fiber connected to a spectrophotometer. Methods for determining one or more tissue parameters comprising: emitting light from a first optical fiber into a tissue; collecting the light reemitted from the tissue with a second optical fiber; generating a spectra of the light reemitted from the tissue with a spectrophotometer; and utilizing a look-up table based algorithm to determine one or more tissue parameters, wherein the lookup-table based algorithm comprises the steps of: generating a look-up table by measuring the functional form of a reflectance measured by the spectrophotometer using one or more calibration standards with known optical properties; and implementing an iterative fitting routine based on the lookup-table.

Abstract: In one embodiment, the invention is a spectrophotometer with a modular 45/0 head. One embodiment of an apparatus for measuring a reflectance of a sample includes a plurality of light emitting diodes for emitting light, a reflective housing positioned above the plurality of light emitting diodes, where the reflective housing is a dome having a plurality of apertures formed around its perimeter, a sample channel for capturing a first portion of the light, where the first portion of the light interacts with the sample, and a reference channel for capturing a second portion of the light, where the second portion of the light is independent of the sample.

Abstract: A computer-implemented method for color calibration and profiling of an output device includes measuring a color patch in a test pattern, which comprises a plurality of color patches, to obtain first image data; measuring the color patch in the test pattern to obtain second image data; transforming the first image data to a first estimated image data; determining a difference between the second image data and the first estimated image data to obtain a correction factor; and calculating, for each patch in the test pattern, a corrected image data by applying the correction factor to a subsequent estimated image data from the first sensor. The correction factor is used for correcting inaccuracies introduced when the first image data is transformed into the first estimated image data. The first image data and the second image data provide a measured color representation of the color patch in a device dependent color space and a device independent color space, respectively.

Abstract: A spectroscopic analysis of a sample includes arranging the sample in a resonator cavity for transmitting cavity mode frequencies with a cavity mode frequency spacing, coupling pulsed source light into the resonator cavity, with the source light including source comb frequencies with a source frequency spacing, coupling pulsed transmitted light out of the resonator cavity, and spectrally resolved detecting the transmitted light with a detector device. The cavity mode frequency spacing and the source frequency spacing are detuned relative to each other, so that the transmitted light includes transmitted comb frequencies with a spacing larger than the source frequency spacing. The detecting feature includes collecting spectral distributions of the transmitted light in dependence on relative positions of the cavity mode frequencies and the source comb frequencies.

Abstract: A fluid content monitor including a cuvette, a colorimeter adapted to generate a signal indicative of contents of a fluid sample contained in the cuvette, a container for holding a reagent, and a pump assembly for delivering reagent from the container to the cuvette. The pump assembly includes a tube extending from the container to the cuvette, check valves preventing reverse flow in the tube, and a hammer driven by a solenoid for repetitively compressing the tube to pump reagent to the cuvette. The cuvette can be removed for cleaning and replacement.

Abstract: The invention relates to an apparatus and method for adapting conventional spectrophotometer cuvettes for use in a vertical light beam spectrophotometer.

Abstract: A method and system for increasing optical instrument calibration and prediction accuracy within and across different optical instrument platforms can comprise two main submethods or routines. The first routine can include one for correcting differences among optical instruments of different model types regardless of the manufacturer and correcting differences among optical instruments of the same model type. The second main routine or sub-method can include one for analyzing new samples of a product over time and maintaining prediction accuracy as compared to a reference method over time. The first routine can include a “TRANS” procedure, a “MIN” procedure, and checkcell tests. The second main routine provides techniques on how a product database can be cleaned, condensed, and expanded automatically as it is used by one or more different optical instruments.

Abstract: The invention application presents a fast, efficient, reproductive alternative of a non-invasive method for diagnosing the severity of heart failure based on a specific biomarker. An additional object of the present invention is a collector device for the biomarker from exhaled breath that is portable, simple, low cost and does not need to run on electric power. This invention advantageously permits the replacement of invasive diagnosis methods, favoring the patient's comfort in addition to the agility and speed of medical attention at hospitals, and may become a standard method for all suspected cases of circulatory disease and heart failure and, more specifically, decompensated heart failure.

Abstract: A method is presented for selecting the order in which parameters are evaluated for inclusion in a model of a film stack, which is by ranking them according to measurement precision. Further, a method is presented for determining which parameters are to be floated, set, or discarded from the model, which is by determining whether average chi-square and chi-square uniformity decreases or increases when the parameter is added to the model. In this manner, a model for the film stack can be quickly assembles with a high degree of accuracy.

Abstract: A surface plasmon resonance instrument and measuring method, in which a lens collimates light into a light beam, a prism propagates the collimated light beam at a single propagation angle and with internal reflection on a face of the prism, and an analyzer processes the collimated light beam from the prism. The face of the prism is configured to receive a surface plasmon resonance sensor and at least the first lens and the prism are aligned on a single optical axis.

Abstract: Provided is a flow-through CO2 system for simultaneously measuring surface seawater pH, carbon dioxide fugacity (fCO2), and total dissolved inorganic carbon (DIC). All measurements are based on spectrophotometric determinations of solution pH at multiple wavelengths using sulfonephthalein indicators.

Abstract: NBT-PVA film dosimeters performance is affected due to high humidity levels. NBT-PVB film dosimeters with a relatively small effect of high humidity levels on its performance are invented. NBT-PVB film dosimeters are made by using alcoholic solution to dissolve both of NBT and PVB. The films are very useful for routine dosimeter in industrial radiation processing. A very high sensitivity NBT-PVB Radio-chromic film dosimeter is achieved due to high solubility of NBT dye in 2-methoxyethanol enabling the addition of very high concentrations of NBT dye in the film dosimeters. The dose response of conventional NBT-PVA dosimeter films are normally saturated after 50 kGy, while the invented composites of NBT-PVB dosimeter films demonstrated high dose range up to 100 kGy for high dose industrial use.

Abstract: A colorimetric instrument includes a power control section adapted to vary the power to be applied to the light source between the wavelengths in accordance with at least one of spectral characteristics of the light source, spectral characteristics of the measurement optical system, and light receiving sensitivity characteristics of the light receiving section.

Abstract: To provide a mercury measuring apparatus of a closed system capable of performing automatically a process ranging from collection to injection of the sample composed mainly of hydrocarbon, which is effective to accomplish a highly reliable measurement. The mercury measuring apparatus 100 includes a column 1 filled with a first adsorbent 11 and a reducing agent 13, an injecting unit 3 for injecting a sample into the column 1, a first heating unit 12, a second heating unit, a mercury collecting tube 18 filled with a second adsorbent 17, a third heating unit 19, a mercury measuring unit 2, gas flow passages FP1, FP2 and FP4, flow switching valves V1 to V3, V5 and V6 for selecting one of the gas flow passages FP1, FP2 and FP4, and a control unit 4.

Abstract: A method for on-line channeling of milk based on predicted coagulation properties where the method comprises sampling raw milk from a milk line between a milking station and a collection point, performing spectral analysis of one or more of optical transmission, optical reflectance, scatter and fluorescence on the raw milk sample, predicting at least one coagulation parameter on-line based on the spectral analysis, and channeling milk from the milking station on-line to one of a plurality of destinations based on the at least one coagulation parameter.

Abstract: A simple method and apparatus for circular dichroism spectrophotometry are provided that allow a liquid, cream-type, and gel-type specimens having a low degree of transparency to be measured directly and nondestructively without passing light through the specimens. Right-handed or left-handed circularly polarized light enters a prism from an entrance face and hits a specimen mounting face of the prism, on which a specimen is placed, at an angle of 80°. Then, after being totally reflected by the specimen mounting face and going out from an exit face, the light is detected, and the absorbance is determined.

Abstract: A spectral measurement device includes an optical band-pass filter section having a spectral band of first to n-th wavelengths (n is an integer of 2 or more), a light receiving section, a correction operation section, and a signal processing section. When an m-th wavelength band (1?m?n) is an interest wavelength band, and a k-th wavelength band (k?m and 1?k?n) other than the m-th wavelength band is a non-interest wavelength band, the optical band-pass filter section functions as a m-th band-pass filter corresponding to the m-th wavelength band and a k-th band-pass filter corresponding to the k-th wavelength band.

Abstract: An apparatus for spectrophotometric analysis comprises a sample reception surface, which is arranged to receive a sample to be analyzed, and a sample contacting surface, which is moveable in relation to the sample reception surface such that it may be brought to a first position, where the surfaces are sufficiently far apart to allow the sample to be placed on the sample reception surface, and a second position, where the sample contacting surface makes contact with the sample and compresses the sample. The apparatus further comprises a sample thickness controller, which is arranged to control the distance between the sample reception surface and the sample contacting surface in the second position of the sample contacting surface, such that a sample thickness between the surfaces may be shifted for obtaining at least two measurements of the sample at different optical path lengths through the sample.

Abstract: A spectrophotometer comprising a monolithic semiconductor substrate, one or more wavelength dispersing means, and one or more wavelength detecting means, wherein the monolithic substrate (1) has waveguide means (2) and one or more resonators (3-14) acting as detectors of particular light wavelengths and disposed in proximity to the waveguide means in such a way that evanescent light coupling can occur for said light wavelengths.

Abstract: A liquid sample is dropped onto the upper surface of a transparent and cylindrical light-transmitting body (22), and the liquid sample is maintained as a droplet by the surface tension. From above the liquid sample, a transparent cover plate (25) is lowered down to the position where the lower surface thereof touches a spacer (23) in order that the liquid sample is held in the small gap formed between the upper surface of the light-transmitting body (22) and the lower surface of the transparent cover plate (25). A measurement light is provided into the liquid sample held in this manner from immediately above it, and passes through the liquid sample. The transmitted light emitted downwards through the light-transmitting body (22) is introduced into a spectro-detecting unit to be spectro-measured. The measurement optical path length can be adjusted by the height of the spacer (23). This enables an easy transmission spectro-measurement of an extremely small amount of liquid sample.

Abstract: MEX3C deficiency impairs the development of white and brown adipose tissue. Hence the present invention provides, among other things, a method of screening a candidate compound for activity in inhibiting fat deposition in a subject in need thereof and/or treating a condition in a subject in need thereof, comprising: (a) contacting a candidate compound to a cell that expresses MEX3C protein; and then (b) detecting a quantity of expression of the MEX3C protein in the cell; a depression in the expression of MEX3C protein when the candidate compound is contacted thereto as compared to that expressed when the candidate compound is not contacted thereto indicating the compound is active in inhibiting fat deposition and/or treating a condition in a subject in need thereof. Methods of treatment and screening subjects are also described.

Abstract: The present disclosure describes the harvesting and use of ambient light in spectrophotometric systems so as to increase the energy efficiency of the systems. In one embodiment, the collected ambient light is filtered and/or converted into discrete wavelengths of light that can then be used in spectrophotometric applications. In one embodiment, the emitted light can then be collected and analyzed to derive various physiological parameters. In certain embodiments, the ambient light may be used in place of light that is electrically generated.

Abstract: Biodegradable waveguides and their uses with devices, such as medical devices, are described. In one embodiment, an optically transmissive fibrous structure comprising biodegradable fiber waveguides may be disposed on a surface of a bandage. The bandage in combination with the optically transmissive fibrous structure may allow for simultaneously monitoring and covering an injured area of a patient. In one embodiment, the fiber waveguides may be provided as multi-channel/multi-core biodegradable fiber waveguides for transmitting light to and from a patient tissue. In some implementations, the bandage may include hydrogel-based biodegradable fiber waveguides that may deliver therapeutics to an injured patient area.

Abstract: An emission spectrophotometer capable of inhibiting non-uniformity of spectral intensities of component elements is provided. The emission spectrophotometer generates pulse light emission by supplying an energy accumulated in an electricity accumulating and discharging unit to a gap between an electrode and a test material, and the emission spectrophotometer includes a detection unit, for detecting an energy charged to the electricity accumulating and discharging unit before the pulse light emission; and a detection unit, for detecting an energy remaining in the electricity accumulating and discharging unit after the pulse light emission. It is determined whether the detected light is emitted by fully using the energy accumulated in the electricity accumulating and discharging unit.

Abstract: When a system is powered on and becomes ready for a measurement, it automatically begins to acquire an interferogram (IFG). When a new IFG is acquired, if a background (BKG) IFG is present in a memory but there is no sample IFG (S2 and S4), the new IFG is compared with the BKG-IFG and, if the two IFGs are identical, the new IFG is added to the BKG-IFG (S5, S6 and S7). When an operator sets a sample in a sample chamber and the new IFG shows a change, the IFG is stored as a sample IFG (S8). Then, a sample measurement is initiated. After that, when a new IFG is found to be identical to the sample IFG stored in the memory (S9 and S10), the new IFG is added to the sample IFG (S13). The sample measurement is completed when the number of sample IFGs stored in the memory has reached a predetermined accumulation number. Thus, the sample measurement is automatically performed, for which the operator only needs to set a sample.

Abstract: The present invention provides methods for assessing a condition in an individual by analyzing a cerebrospinal fluid sample from the individual, for example, by spectroscopy. Further, the invention provides methods for determining an amount of blood in the cerebrospinal fluid sample; methods for determining concentrations of analytes in the cerebrospinal fluid sample; methods for determining a length of time the blood has been in the cerebrospinal fluid sample; and methods for rapidly obtaining a differential diagnosis between conditions indicated by blood in the cerebral spinal fluid. Moreover, the present invention provides instruments capable of rapidly assessing a condition in and individual by point-of-care analysis of a cerebral fluid sample from an individual.

Abstract: This invention provides methods of quantitating nucleic acids from problematic samples, such as aged samples, formalin fixed samples, paraffin embedded samples, samples with aneuploid cells, and cells with fragmented nucleic acids. Methods include techniques to efficiently solubilize the nucleic acids under non-denaturing conditions from preserved clinical samples without resort to organic extractions, to normalize cell counts regardless of aneuploidy, to access the fragmentation state of the nucleic acids, and to provide standard curves for degraded nucleic acid samples.

Abstract: The apparatus and methods herein provide light sources and spectral measurement systems that can improve the quality of images and the ability of users to distinguish desired features when making spectroscopy measurements by providing methods and apparatus that can improve the dynamic range of data from spectral measurement systems.

Abstract: A method for determining simultaneously from an oxidized black liquor sample an amount of sulfide, an amount of total dissolved solids, and an amount of effective alkali present in the sample, wherein the sulfide amount, the total dissolved solids amount, and the effective alkali amount are determined by subjecting the sample to attenuated total reflection (ATR) ultraviolet/visible (UV/V) spectroscopy over a wavelength of from about 190 to about 500 nm. Data from analyzing oxidized black liquor samples, and from analyzing one or more black liquor samples which may be subjected to black oxidation, may be used in a black liquor oxidation (BLOX) system for monitoring and/or controlling sulfur emissions from a kraft process.

Abstract: An apparatus for spectrophotometric analysis comprises a sample reception surface, which is arranged to receive a sample to be analysed, and a sample contacting surface, which is moveable in relation to the sample reception surface such that it may be brought to a first position, where the surfaces are sufficiently far apart to allow the sample to be placed on the sample reception surface, and a second position, where the sample contacting surface makes contact with the sample and compresses the sample. The apparatus further comprises a sample thickness controller, which is arranged to control the distance between the sample reception surface and the sample contacting surface in the second position of the sample contacting surface, such that a sample thickness between the surfaces may be shifted for obtaining at least two measurements of the sample at different optical path lengths through the sample.

Abstract: A method and system are provided to correct differences among multiple spectrophotometers. In one form, one spectrophotometer of a plurality that may be present in an image rendering system is treated as “primary”. Additional spectrophotometers are treated as “secondary”. The spectrum of a color from a secondary spectrophotometer is transformed by a linear transformation to an adjusted spectrum, which then is converted to L*a*b* (if desired) using standard techniques. The L*a*b* thus produced is, on average, substantially closer to the L*a*b* that the primary spectrophotometer would have produced when measuring the same color than it is to the L*a*b* that the secondary spectrophotometer would have produced without any correction. The linear transformation is generated by linear regression to minimize the spectral error, followed by non-linear optimization to minimize the error relative to a color difference metric—such as DeltaE 2000.

Abstract: Various environmental systems are disclosed. In accordance with one of the systems, a first and second valve are provided. The valves provide a first air flow path from an air pump to a photo-ionization detector is provided through a pre-filter. The valves also provide a second air flow path from the air pump to the photo-ionization detector so that the pre-filter is isolated from its environmental surroundings. Various other arrangements of environmental monitoring systems with one or more pre-filters are also disclosed.

Abstract: An apparatus for spectrophotometric analysis comprises a sample reception surface, which is arranged to receive a sample to be analysed, and a sample contacting surface, which is moveable in relation to the sample reception surface such that it may be brought to a first position, where the surfaces are sufficiently far apart to allow the sample to be placed on the sample reception surface, and a second position, where the sample contacting surface makes contact with the sample and compresses the sample. The apparatus further comprises a sample thickness controller, which is arranged to control the distance between the sample reception surface and the sample contacting surface in the second position of the sample contacting surface, such that a sample thickness between the surfaces may be shifted for obtaining at least two measurements of the sample at different optical path lengths through the sample.

Abstract: A method for the assessment of a multiphase (aqueous and organic) sample phase, the method comprising adding at least one detection molecule to the multiphase sample; detecting a signal emitted from the detection molecule/multiphase sample mixture, the signal being detectably different when the at least one detection molecule is present in one of either an organic phase, an aqueous phase or an interface between said organic phase and said aqueous phase of the multiphase sample; and analysing the detected signal to assess the properties of a phase or an interface between phases. A system for use in such a method, use of at least one detection molecule for the assessment of a multiphase sample, and a composition for use in the assessment of a multiphase sample are also disclosed.

Abstract: A miniature flow-through cuvette for spectrophotometric measurement of a liquid sample includes a cuvette body of a transparent material including a first outer surface and an opposing second outer surface, and a flow channel disposed through the cuvette body. The flow channel includes first and second interface segments generally vertically oriented, each having an open exit; a measurement segment interconnecting the first and second interface segments; a first inclined planar inner surface disposed in a turning segment between the first interface segment and the measurement segment, facing the first outer surface; and a second inclined planar inner surface disposed in a turning segment between the second interface segment and the measurement segment, facing the second outer surface. The first and second inclined inner surfaces terminate the measurement segment at opposing ends thereof. Further provided is a spectrophotometer including the miniature flow-through cuvette.

Abstract: The invention relates to a method for generating calibrated colour data of a target using colour measurement instruments distributed in the network comprising the steps A) generating at least one standard instrument profile for the colour measurement instruments distributed in the network to correct photometric and wavelength scale differences, and B) generating at least one geometry instrument profile for the colour measurement instruments distributed in the network to correct geometry scale differences. The method can be used in applications where colour measurement instrument networks are used, particularly in robotic systems where colour measurement instruments are integrated.

Abstract: A data compression technique is disclosed for Fourier Transform Mass Spectrometry (FTMS). A statistical analysis is applied to the data in the frequency domain since most of this data is a result of randomly distributed electronic noise. A fit of the whole frequency dataset to the distribution is made to determine preliminary moments of the distribution. The data in the tail of that distribution (which is mainly the peak data) is then removed and the remaining data points are re-fitted to the distribution, to identify the moments of distribution of that remaining noise data. A noise threshold for the mass spectrum is then applied using the calculated moments. The data above the threshold is kept. The whole spectrum can be reconstituted by storing the moments of distribution along with the peak data and then regenerating the noise from those moments and adding it to the peak data.

Abstract: A multi-channel arrayed isosbestic wavelength detection system comprises an arrayed light source board, an arrayed photoelectric sensor board, and an intermediate system frame. The arrayed light source board and arrayed photoelectric sensor board are assembled at opposite sides of the intermediate system frame. In addition, the arrayed light source system has a plurality of light-emitting elements, each of which comprises two monochromatic light sources that provide main wavelength and reference wavelength respectively, and the two wavelengths are isosbestic wavelengths. The arrayed photoelectric sensor system has a plurality of photoelectric sensors, which are aligned at fixed positions in one-to-one correspondence with the light-emitting elements.

Abstract: The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metabolites), dopamine, dopamine metabolites, serotonin, serotonin metabolites, or fasting triglycerides, wherein one or more of: (a) NE metabolites, (b) NE/NE metabolites:dopamine/dopamine metabolites, (c) NE and serotonin, (d) NE/NE metabolites and serotonin, (e) NE and serotonin metabolites, (f) NE/NE metabolites and serotonin metabolites, or (g) NE is/are greater than about 30% over normal level; or dopamine/dopamine metabolites are less than about 30% below normal; or fasting triglycerides are greater than about 150 mg/dl and/or said patient has blood pressure of greater than about 135/85 mm Hg. The present invention is also directed to treating identified patients with dopamine agonist therapy.

Abstract: Quantitative comparison or calculation of a plurality of images in different transmission bands is facilitated even if the transmission bandwidth of the spectroscopic element is different at different wavelengths.

Abstract: A calibration device 21 according to the present invention is a member used for white calibration of an optical characteristic measuring apparatus 1 for measuring an optical characteristic of a specimen arranged to close a measuring opening and is used together with a spacer 24. Accordingly, such a calibration device 21 can perform more accurate white calibration by preventing formation of an interference pattern by the spacer 24.

Abstract: An analysis system, tool, and method for performing downhole fluid analysis, such as within a wellbore. The analysis system, tool, and method provide for a tool including a spectroscope for use in downhole fluid analysis which utilizes an adaptive optical element such as a Micro Mirror Array (MMA) and two distinct light channels and detectors to provide real-time scaling or normalization.

Abstract: A multi-channel detector assembly for downhole spectroscopy has a reference detector unit optically coupled to a reference channel of a source and has a measurement detector unit optically coupled to a measurement channel of the source. The reference and measurement detectors detect spectral signals across a spectral range of wavelengths from the reference and measurement channels. Conversion circuitry converts the detected spectral signals into reference signals and measurement signals, and control circuitry processes the reference and measurements signals based on a form of encoding used by the source. Then, the control circuitry can control the output of spectral signals from the source based on the processed signals or scale the measurement signal to correct for source fluctuations or changes in environmental conditions.

Abstract: When the apparatus is energized or a validation check is performed, a deuterium lamp 10 is turned on, and an output value resulting from an A/D conversion of the detection signal for light with a wavelength of 235 nm is obtained. A data processor 22 compares the output value with an upper limit value, which was determined and stored beforehand in a memory 24 (normally, in the manufacturing stage of the apparatus). If the output value is not less than the upper limit, a controller 25 operates an aperture driver 31 to reduce the light quantity by means of an adjustable aperture 30. This operation prevents an excessive quantity of light from reaching a photodetector 19, so that the measurement without absorption by a sample solution 18 can be correctly performed, and the absorbance by the sample solution 18 can be correctly calculated.

Abstract: A method and apparatus for monitoring water and other fluid systems is described. The fluid is continually monitored spectrophotometrically by measuring many optical parameters in an in-line, on-line system, which compensates for normal fluid changes while detecting abnormalities.

Abstract: A Fourier Transfer Infrared (FTIR) spectrophotometer having reduced baseline noise. The system and method include internal or external optical adapters having a moveable beamsplitter for splitting the source light beam into a reference beam and a sample beam, and may include a variable bandpass filter, variable preamplifier and reversed biased photodiodes.

Abstract: A Fourier Transfer Infrared (FTIR) spectrophotometer having reduced baseline noise. The system and method include internal or external optical adapters having a moveable beamsplitter for splitting the source light beam into a reference beam and a sample beam, and may include a variable bandpass filter, variable preamplifier and reversed biased photodiodes.

Abstract: Method and apparatus for spectrophotometric characterization of turbid materials are provided. An incident light beam is used to illuminate a turbid material sample and optical signals of coherent reflectance, diffuse reflectance, collimated transmittance and diffuse transmittance are measured from the sample as functions of wavelength. The following optical parameters are determined as functions of wavelength for spectrophotometric characterization of the turbid material sample in the spectrum of interest: absorption coefficients ?a, scattering coefficient ?s, anisotropy factor g and real refractive index n.