Therapy Patents (Class 378/65)
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Patent number: 9486839Abstract: An apparatus and a method for sorting scrap metal containing at least two categories of metals are provided. An x-ray beam is directed towards at least a portion of a particle of scrap metal. Backscattered x-rays, forward scattered x-rays, and transmitted x-rays from the particle are measured and input into a classifier, such as a database with a cutoff plane. The scrap metal is sorted into a first category and a second category on the scrap metal by a controller. An x-ray source for a scanning system is provided with an electron beam generator, an electromagnetic beam focusing coil, a pair of saddle shaped beam steering coils, and a target foil to create a scanning x-ray beam along a plane.Type: GrantFiled: January 6, 2012Date of Patent: November 8, 2016Assignee: Huron Valley Steel CorporationInventors: Paul Torek, Daniel F. Gorzen, Kalyani Chaganti
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Patent number: 9486645Abstract: The present invention advantageously provides a method and system for providing accurately localized, non-invasive radiation treatment for ocular melanoma or other intraocular indications through the completion of specified research tasks. The present invention further provides for dynamic localization of tumors associated with such indications. The system of the present invention includes the CYBERKNIFE system, a robust eye pupil tracking system, and an integrated software package to achieve intra-beam fractional tumor tracking during radiation delivery. The system may further include a mechanical phantom incorporated with a radiation dosimetry calibration kit for validation.Type: GrantFiled: December 8, 2014Date of Patent: November 8, 2016Assignee: University of MiamiInventors: Xiaodong Wu, Weizhao Zhao
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Patent number: 9474913Abstract: A teletherapy treatment arrangement constituted of: a control unit; a 3 dimensional imager having an effective patient plane; at least one 2 dimensional imager arranged to provide a pair of 2 dimensional images along planes generally orthogonal to the effective patient plane of the 3 dimensional imager; and a patient positioner arranged to secure a target tissue in a fixed relationship to the patient positioner, the control unit arranged to: input a planned treatment position of the patient target tissue; in the event that the planned treatment position is consonant with the effective patient plane of the 3 dimensional imager, obtain position information of the target tissue from the 3 dimensional imager, and in the event that the planned treatment position is not consonant with the effective patient plane of the 3 dimensional imager, obtain position information of the target tissue from the at least one 2 dimensional imager.Type: GrantFiled: April 29, 2012Date of Patent: October 25, 2016Assignee: P-CURE, LTD.Inventor: Michael Marash
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Method and a system for optimizing a radiation treatment plan based on a reference dose distribution
Patent number: 9468776Abstract: A computer-based method for generating an improved radiation therapy treatment plan for a treatment volume having a target and an organ-at-risk. The method includes a step of accessing an existing radiation therapy treatment plan from a memory of a computer, a dose distribution of the existing radiation therapy treatment plan serving as a reference dose distribution; and performing machine parameter optimization on the existing radiation therapy treatment plan with the computer by pursuing an optimization goal to minimize doses to the organ-at-risk, thereby generating the improved radiation therapy treatment plan.Type: GrantFiled: June 1, 2012Date of Patent: October 18, 2016Assignee: RaySearch Laboratories ABInventor: Albin Fredriksson -
Patent number: 9462991Abstract: Systems and methods for remote diagnostic imaging. The systems include a diagnostic imaging kiosk. The kiosk includes, for example, a first housing module and a second housing module. The first housing module is configured to house, among other things, a diagnostic imaging system (e.g., an X-ray system). The second housing module is configured to house electronics associated with the operation, control, and networking of the kiosk. The electronics include, for example, a primary controller, an X-ray controller, an X-ray generator, an internal display controller, an external display controller, one or more routers, and a digital radiology module. The kiosk is configured to communicatively connect to a remote technician's workstation, and a remote technician at the workstation is able to remotely control the kiosk through a packet-switched network.Type: GrantFiled: September 3, 2013Date of Patent: October 11, 2016Assignee: Merge Healthcare IncorporatedInventor: Michael W. Ferro, Jr.
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Patent number: 9463336Abstract: A system for evaluating radiation treatment planning generates a fictitious treatment dose matrix with a quality of dose placement beyond that achievable with physically realizable radiation therapy machines. Such a fictitious treatment dose matrix provides an objective measure that is readily tailored to different clinical situations, and although unattainable, thereby provides a benchmark allowing evaluation of radiation plan goals and the radiation plans between different multiple clinical situations and individuals.Type: GrantFiled: October 11, 2013Date of Patent: October 11, 2016Assignee: Sun Nuclear CorporationInventor: Benjamin E. Nelms
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Patent number: 9451923Abstract: According to one embodiment, the x-ray apparatus comprises an x-ray source adapted to emit an x-ray beam, a detector adapted to receive the x-ray beam of the x-ray source, wherein the x-ray source is adapted to be moved in relation to a first portion of the x-ray apparatus, wherein the detector is adapted to be moved in relation to a first portion of the x-ray apparatus, the x-ray apparatus further comprising a control unit for controlling the movement of the x-ray source and detector, wherein the x-ray source and the detector are adapted to rotate in relation to a first portion of the x-ray apparatus, wherein further the x-ray beam is directed essentially towards the detector during the movement of the x-ray source and the detector.Type: GrantFiled: June 27, 2012Date of Patent: September 27, 2016Assignee: Koninklijke Philips N.V.Inventors: Magnus Hemmendorff, Torbjorn Hjarn, Mats Lundqvist, Jonas Rehn
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Patent number: 9437340Abstract: The invention relates to a leaf module (102) for a multi-leaf collimator (132), comprising a leaf unit (104) and a leaf drive unit (106), wherein the leaf unit (104) comprises a leaf (108) for shielding beams from a selected area, and the leaf unit (104) is mounted displaceably in an adjusting direction (110), wherein the leaf drive unit (106) is designed to displace the leaf unit (104) linearly in the adjusting direction (110), and wherein the leaf drive unit (106) comprises at least one drive mechanism (112), being designed in such a way that the drive mechanism (112) operates based on pneumatic actuation. Furthermore, the invention relates to a multi-leaf collimator (132) comprising a plurality of leaf modules (102) according to the invention. The invention is based on the objective of designing a leaf module (102) and a multi-leaf collimator (132) as compactly as possible, while achieving a simple, reliable and variable adjustability of the leaf unit (104).Type: GrantFiled: July 18, 2013Date of Patent: September 6, 2016Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRUM, PRECISIS AGInventors: Gernot Echner, Armin Runz, Martin Baumann, Stefan Ueltzhöffer
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Patent number: 9409039Abstract: The present invention proposes a method for automatically creating a dose prediction model based on existing clinical knowledge that is accumulated from multiple sources without collaborators establishing communication links between each other. According to embodiments of the claimed subject matter, clinics can collaborate in creating a dose prediction model by submitting their treatment plans into a remote computer system (such as a cloud-based system) which aggregates information from various collaborators and produces a model that captures clinical information from all submitted treatment plans. According to further embodiments, the method may contain a step where all patient data submitted by a clinic is made anonymous or the relevant parameters are extracted and condensed prior to submitting them over the communications link in order to comply with local regulations.Type: GrantFiled: September 27, 2013Date of Patent: August 9, 2016Assignee: Varian Medical Systems International AGInventors: Joona Hartman, Maria Cordero Marcos, Esa Kuusela, Jarkko Peltola, Janne Nord
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Patent number: 9405021Abstract: The present invention relates to an X-ray parameter measuring arrangement comprising a detector for measuring said parameter configured to be positioned in a position adjacent to an x-ray source arranged to generate a ray formation having a primary ray portion for radiating an object. The position is chosen in such a way that the interference with a reproduced image is reduced or eliminated.Type: GrantFiled: June 3, 2013Date of Patent: August 2, 2016Assignee: Unfors Raysafe ABInventor: Tomas Unfors
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Patent number: 9403035Abstract: The present invention relates to a method for positioning an arrangement of at least one beam position relative to a patient's body when the patient is placed for treatment by means of a treatment device which can emit treatment radiation, wherein the at least one beam position describes at least one position of at least one treatment beam, wherein the arrangement is referred to as the treatment arrangement and the treatment beam comprises the treatment radiation, wherein the method is executed by a computer and comprises the following steps: providing treatment beam absorption data which describe the absorption properties of the at least part of the body with respect to absorbing the treatment radiation, and the relative position between the at least part of the body and the treatment arrangement; providing treatment beam data which describe radiation properties of the at least one treatment beam; providing condition data which describe a condition for treating the at least part of the body; determining anType: GrantFiled: August 2, 2011Date of Patent: August 2, 2016Assignee: Brainlab AGInventors: Franz Gum, Stephan Froehlich
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Patent number: 9403037Abstract: The invention relates to in vivo dosimetry techniques and can be used for comparison of dose measured in reference point and dose calculated at the same place with computerized treatment planning system. The suggested method takes into consideration dose difference and distance-to-agreement between measured and calculated points and uses a region of measurements (ROM) contoured as an organ at risk so that dose differences inside the ROM and acceptance interval are defined with the dose volume histogram of the ROM. The method can be used for evaluation of influence of ROM homogeneity and dosimeter movement on the difference between calculated and measured doses.Type: GrantFiled: October 10, 2013Date of Patent: August 2, 2016Inventors: Victor Alexander Gurvich, John Marian Pacyniak
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Patent number: 9393442Abstract: The invention relates to a device for determining illumination distributions (18) for IMRT. A layered graph structure is used, which considers which extensions of an illumination distribution along a respective line and thus which illumination distributions are realizable, for determining extensions for the illumination distributions. Moreover, second weights defining fluences of the illumination distributions are determined such that a deviation between a provided fluence map and a fluence map formed by a combination of illumination distributions, which are defined by the respective determined extensions and the respective second weight, is minimized. This determination procedure leads to illumination distributions, which very well correspond to the provided fluence map and which are automatically realizable by the radiation device.Type: GrantFiled: May 14, 2014Date of Patent: July 19, 2016Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Alfonso Agatino Isola, Christoph Neukirchen, Juergen Weese, Matthieu Frédéric Bal
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Patent number: 9393446Abstract: One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base and coupled to the X-ray applicator. The X-ray applicator may have an X-ray tube configured to emit an X-ray beam through an exit window to irradiate an object. The mobile X-ray unit may further include a dosimetry system adapted for real time dosimetry.Type: GrantFiled: March 2, 2015Date of Patent: July 19, 2016Assignee: Nucletron B.V.Inventors: Johannes Simon van der Veen, Bas Woudstra, Johan Henning
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Patent number: 9387342Abstract: A method of delivering external radiation beams to a target volume in a body portion includes positioning a radioactive isotope source at a plurality of locations spaced apart around the body portion, and collimating radiation beams of the radioactive isotope source from the plurality of locations, whereby the target volume in the body portion is deposited with a predetermined dose distribution. A radiation device employs a member having a configuration adapted to surround a body portion to be irradiated. The member has a channel and a plurality of collimators spaced apart along and coupled to the channel. The plurality of collimators define a plurality of dwelling locations for a radioactive isotope source in the channel and are configured to collimate radiation beams of the radioactive isotope source.Type: GrantFiled: July 21, 2008Date of Patent: July 12, 2016Assignee: Varian Medical Systems, Inc.Inventors: Stavros Prionas, Michael C. Green, Edward Seppi, Larry D. Partain, James Clayton, Stanley Mansfield, John Boone
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Patent number: 9387345Abstract: A control circuit optimizes a radiation-treatment plan (as regards treating at least one target volume for a given patient) by automatically determining a spatially-variant normal tissue constraint as a function, at least in part, of dose distribution for normal tissue that is proximal to the target volume. If desired, the control circuit can repeatedly determine spatially-variant normal tissue constraints while optimizing the radiation-treatment plan. This automatic determination can comprise evaluating dose distributions at specific different distances from the target volume. So configured, the control circuit can effect such evaluation by penalizing, during the optimization of the radiation-treatment plan, dose distribution levels that exceed a predetermined distribution property (such as an aggregation value for the dose values including, but not limited to, an average value of dose values for each of the given specific different distances) at a given one of the specific different distances.Type: GrantFiled: July 13, 2012Date of Patent: July 12, 2016Assignee: Varian Medical Systems International AGInventors: Janne Nord, Jarkko Peltola
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Patent number: 9381376Abstract: Systems, devices, and methods for quality assurance for verification of radiation dose delivery in arc-based radiation therapy devices using a 3D gamma evaluation method.Type: GrantFiled: October 12, 2012Date of Patent: July 5, 2016Assignee: VARIAN MEDICAL SYSTEMS INTERNATIONAL AGInventors: Lasse Heikki Toimela, Janne Nord
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Patent number: 9364686Abstract: A method and an apparatus for planning a treatment beam aimed at at least one target region are provided. Planning parameters having associated predetermined parameter values are for performing a treatment that is to be applied with the treatment beam. The method includes defining a first predetermined parameter value of the planning parameters that is suitable for the irradiation of a treatment region that includes at least one target region. The method also includes ascertaining, based on the first predetermined parameter value, a first probability distribution in relation to an optimizable variable that is prespecified based on deviations to be expected when carrying out the irradiation.Type: GrantFiled: March 6, 2014Date of Patent: June 14, 2016Assignee: Siemens AktiengesellschaftInventors: Mark Hastenteufel, Markus Stoll
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Patent number: 9364186Abstract: A method for the reconstruction of a dose administered in an object to be irradiated includes providing a radiation therapy device. The radiation therapy device includes a therapeutic radiation source for emitting a therapeutic treatment beam, a portal detector opposing the therapeutic radiation source for recording measurement data of the treatment beam once the therapeutic radiation source has left the object to be irradiated, and a single or multi slice computed tomography scanner having a kV x-ray source and an opposing kV detector for producing a computed tomography of the object positioned in the radiation therapy device. The method also includes recording a computed tomography image of the object to be irradiated with the computed tomography scanner, and using the computed tomography image in order to reconstruct a dose administered to the object from measurement data of the portal detector.Type: GrantFiled: November 2, 2012Date of Patent: June 14, 2016Assignee: Siemens AktiengesellschaftInventor: Elena Nioutsikou
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Patent number: 9355447Abstract: A system and method for analyzing medical images of a subject includes acquiring the medical images of the subject and texture images. A computer system determines, using the medical images and the texture feature images, a plurality of segmentation surfaces by iteratively adjusting a relationship between a region growing algorithm that selects a region of interest (ROI) to determine a given segmentation surface and cost function for evaluating the given segmentation surface. The computer system generates a report using the plurality of segmentation surfaces indicating at least boundaries between anatomical structures with functional differences in the medical images.Type: GrantFiled: August 21, 2013Date of Patent: May 31, 2016Assignee: Wisconsin Alumni Research FoundationInventors: Paulina E. Galavis, Bhudatt Paliwal, James Holden, Robert Jeraj
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Patent number: 9339243Abstract: A radiation treatment and imaging system for emitting a radiation treatment beam and X-ray imaging beams towards an object. The system includes an x-ray source and a collimator, first and second detectors, and a linear accelerator that delivers radiation beams to an object. The linear accelerator includes a radiation source positioned between the first and second detectors and emitting a therapy radiation beam in-line with the x-ray beams received by the first and second detectors. The system also includes a data processing device in communication with the first and second detectors. The data processing device receives imaging signals from the first and second detectors and reconstructs a three-dimensional tetrahedron beam computed tomography (TBCT) image from the received imaging signals. The system also includes a display in communication with the data processing device and for displaying the TBCT image.Type: GrantFiled: May 12, 2014Date of Patent: May 17, 2016Assignee: WILLIAM BEAUMONT HOSPITALInventors: Tiezhi Zhang, Joshua Kim
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Patent number: 9327139Abstract: A method for determining a radiation therapy dose distribution starts with selecting and downloading a treatment type from a database. Then an organ at risk (OAR) distance to target map is determined, wherein the OAR distance to target map comprises distances to a target organ for respective portions of at least one OAR, and wherein the OAR distances are determined from at least one segmented patient organ image. Now a cohort average dose distance to target histogram is selected and downloaded from the database. After which, a dose value to the portions of the at least one OAR are assigned to form a first 3D dose distribution map, wherein the dose values are from the selected cohort average dose distance to target histogram. Now a second 3D dose distribution map is determined based on a field arrangement determined by the treatment type, and the first 3D dose distribution map.Type: GrantFiled: May 30, 2014Date of Patent: May 3, 2016Assignee: Varian Medical Systems, Inc.Inventor: Corey Zankowski
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Patent number: 9314647Abstract: The present embodiments relate to a holding arm for a detector that may be positioned on a first arm end or a diagnostic beam source that may be positioned on the first arm end. The present embodiments also relate to a radiation therapy arrangement with the holding arm. The holding arm may be positioned in a region of a second arm end in an emitter head region of a radiation therapy system and is essentially curved.Type: GrantFiled: August 12, 2011Date of Patent: April 19, 2016Assignee: Siemens AktiengesellschaftInventors: Franz Dirauf, Franz Fadler, Christian Ziegler
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Patent number: 9308394Abstract: A particle beam irradiation system having a multi-energy extraction control operation that controls the extraction beam energy in a synchrotron within a short time, such that when the ion beam irradiation is halted, an operating cycle is updated within a short time and a dose rate is improved. To this end, operating control data for each of the devices constituting the synchrotron is constructed by multi-energy extraction control pattern data for controlling extraction of beams of a plurality of energy levels at one operating cycle, and a plurality of sets of deceleration control data that correspond to the extraction control of the beam of the plurality of energy levels. The devices are controlled by using the operating control data.Type: GrantFiled: July 18, 2013Date of Patent: April 12, 2016Assignee: HITACHI, LTD.Inventors: Hideaki Nishiuchi, Masumi Umezawa, Takuya Nomura, Satoshi Totake, Koji Tobinaga, Tomohisa Imagawa, Seiji Yoshiura, Moemi Takeda
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Patent number: 9308395Abstract: A radiation system includes a support, a capsule rotatably coupled to the support, a radiation source movably coupled to the capsule, wherein the radiation source is configured to provide a treatment radiation beam, and is capable of being turned on or off in response to a control signal, and a collimator located next to the radiation source, wherein the capsule defines a space for accommodating a portion of a patient, and includes a shielding material for attenuating radiation resulted from an operation of the radiation source, and wherein the shielding material is configured to limit a radiation exposure level to 5 mR/hr or less within 3 meters from an isocenter.Type: GrantFiled: December 2, 2011Date of Patent: April 12, 2016Assignee: VARIAN MEDICAL SYSTEMS, INC.Inventors: John R. Adler, Jr., David H. Whittum, Steven W. Prince, James E. Clayton
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Patent number: 9302123Abstract: A gantry structure (16) designed for pivoting about an axis of rotation (18) and for delivering a hadron beam on a target comprises a beam delivery line (24) receiving the hadron beam in a direction essentially parallel to the axis of rotation (18), deviating it away from said axis of rotation (18) and delivering it so that the axis of the beam intersects the axis of rotation (18). The beam delivery line (24) is a self-supporting structure supported by a pivotable support arm (32) in proximity of the center of gravity of the beam delivery line (24). A counterweight (42) is supported by a support arm extension (40) on the other side of the axis of rotation (18) for compensating the moment of force due to the weight of the beam delivery line (24) and the support arm (32).Type: GrantFiled: December 21, 2012Date of Patent: April 5, 2016Assignee: Ion Beam Applications S.A.Inventor: Jean-Claude Amélia
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Patent number: 9289627Abstract: Methods are provided for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject. One such method comprises: determining a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification; for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing the projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; modifying the intensity values of at least one of the dose-change beamlets; and updating the achievable dose distribution estimate to account for the modified intensity values of the at least one of the dose-change beamlets.Type: GrantFiled: June 22, 2011Date of Patent: March 22, 2016Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 9283403Abstract: Described herein are systems and methods for positioning a radiation source with respect to one or more regions of interest in a coordinate system. Such systems and methods may be used in emission guided radiation therapy (EGRT) for the localized delivery of radiation to one or more patient tumor regions. These systems comprise a gantry movable about a patient area, where a plurality of positron emission detectors, a radiation source are arranged movably on the gantry, and a controller. The controller is configured to identify a coincident positron annihilation emission path and to position the radiation source to apply a radiation beam along the identified emission path. The systems and methods described herein can be used alone or in conjunction with surgery, chemotherapy, and/or brachytherapy for the treatment of tumors.Type: GrantFiled: March 30, 2012Date of Patent: March 15, 2016Assignee: RefleXion Medical, Inc.Inventors: Samuel Mazin, Akshay Nanduri
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Patent number: 9282941Abstract: A method for imaging with a radiotherapy device is provided. The radiotherapy device includes a movably mounted imaging apparatus with an X-ray source and an oppositely disposed X-ray detector. The method includes preparing a first image with the imaging apparatus from a first imaging direction. The imaging apparatus is moved to a position that permits the preparation of a second image from a second imaging direction extending at an angle to the first imaging direction. The method also includes preparing the second image with the imaging apparatus from the second imaging direction, and verifying the position of an object to be irradiated using the first image and the second image.Type: GrantFiled: November 7, 2012Date of Patent: March 15, 2016Assignee: Siemens AktiengesellschaftInventors: Michael Grasruck, Robert Heiter
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Patent number: 9272160Abstract: Bracytherapy devices include a respective tether attached to a proximal end portion of the strands. The tether can be color-coded to match a color associated with the corresponding strand.Type: GrantFiled: August 3, 2011Date of Patent: March 1, 2016Assignee: Wake Forest University Health SciencesInventors: Andrew Karim Kader, Daniel B. Fried
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Patent number: 9269137Abstract: Embodiments of the invention provide systems and methods for evaluating treatment parameters for a patient undergoing radiotherapy. The method includes the step of generating a portal dosimetry image showing differences between a planning image obtained prior to a treatment session and a portal image obtained during the treatment session. A database of prior portal dosimetry results is accessed, and a processor is used to perform a similarity measurement between the portal dosimetry image and the prior portal dosimetry results. Based on the similarity measurement, the system determines whether radiation was delivered as planned during the treatment session.Type: GrantFiled: June 26, 2013Date of Patent: February 23, 2016Assignee: ELEKTA AB (PUBL)Inventors: Colin Winfield, Abdul Sayeed
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Patent number: 9262685Abstract: Provided is a method of generating a model, the method including generating a first model representing a change in the location or the shape of the region of interest during the respiration cycle, using diagnostic images that are obtained at two points of time in the respiration cycle and that represent the region of interest; extracting shape information of one or more tissues included in the region of interest at a shape information extractor, using a 3D ultrasound image that is obtained at one point of time in the respiration cycle; determining a characteristic point of the 3D ultrasound image corresponding to a characteristic point of the first model by matching the first model with the extracted shape information; and generating a second model by updating the first model with the determined characteristic point.Type: GrantFiled: December 2, 2013Date of Patent: February 16, 2016Assignee: Samsung Electronics Co., Ltd.Inventors: Young-kyoo Hwang, Na-hyup Kang, Do-kyoon Kim, Jung-bae Kim, Young-taek Oh, Hyong-euk Lee
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Patent number: 9254396Abstract: A method of radiotherapy treatment planning is described. A planned target volume is identified for radiotherapy treatment and at least one volume of interest is identified. The mass, density, and total deposited energy contained in the planned target volume and the volumes of interest are identified and dose objectives are determined. At least one of the objectives is a function of the identified mass, density, or deposited energy. A composite objective function is determined using the dose objectives for the planned target volume and the volumes of interest. A near optimal solution to the composite objective function is determined to produce a radiotherapy treatment plan.Type: GrantFiled: February 15, 2013Date of Patent: February 9, 2016Assignee: Rhode Island HospitalInventor: Ivaylo B. Mihaylov
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Patent number: 9254113Abstract: The X-ray imaging apparatus includes an X-ray generator to generate and emit X-rays, an X-ray detector to detect the emitted X-rays and acquire X-ray data, and a controller to convert the X-ray data into X-ray characteristic coordinates and estimate a response characteristic function of the X-ray detector from a relationship between measurement data and reference data, the measurement data and the reference data being converted into the X-ray characteristic coordinates.Type: GrantFiled: December 9, 2013Date of Patent: February 9, 2016Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Sung Su Kim, Hyun Hwa Oh, Dong Goo Kang, Sung Hoon Kang, Young Hun Sung, Kang Eui Lee, Seok Min Han
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Patent number: 9251302Abstract: A method for planning a radiation therapy treatment of a body represented by a volume of voxels determines a radiation dose matrix representing a spatial distribution of a radiation dose of beams of radiation irradiating the volume with homogeneous stopping power. The beams are collimated and are shifted copies of each other at each depth of the volume, and the spatial distribution is determined by calculating cumulative beam-axial doses in a single matrix-matrix multiplication and redistributing the cumulative beam-axial doses to all voxels in the volume using a convolution. Next, a set of correcting operations is applied to the radiation dose matrix to produce a cumulative voxel radiation dose of the volume. Each correcting operation is linear, independent from another correcting operation and has a transform.Type: GrantFiled: January 14, 2014Date of Patent: February 2, 2016Assignee: Mitsubishi Electric Research Laboratories, Inc.Inventor: Matthew Brand
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Patent number: 9238151Abstract: A facility for facilitating custom radiation treatment planning is described. During a distinguished radiation treatment session for a patient, the facility collects data indicating positioning of a predefined treatment site of the patient relative to a target treatment location throughout the distinguished radiation treatment session. The facility associates the collected positioning data with data describing one or more other aspects of the distinguished radiation treatment session. The facility provides the associated data to a treatment planning facility to determine a treatment plan for future radiation treatment sessions for the patient.Type: GrantFiled: May 6, 2013Date of Patent: January 19, 2016Assignee: Varian Medical Systems, Inc.Inventors: James K. Riley, Eric Meier, J. Nelson Wright, Steven C. Dimmer, Timothy P. Mate
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Patent number: 9237860Abstract: Medical imaging and localization methods and systems for producing a motion-compensated image of a planning target volume (PTV) of a patient. In one embodiment, an imaging and localization system includes sensors that are positioned to receive an electromagnetic location signal from one or more active markers affixed to or adjacent a PTV. A signal processing component can produce real-time localization data corresponding to the location signal, and a system interface can receive such localization data. The system interface can also receive raw image data from an imaging subsystem and process the raw image data based on the localization data. For example, the imaging subsystem can include a computed tomography (CT) imaging system and image slices or frames can be binned based on the localization data.Type: GrantFiled: June 5, 2009Date of Patent: January 19, 2016Assignee: Varian Medical Systems, Inc.Inventors: Parag J. Parikh, Steven C. Dimmer
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Patent number: 9226720Abstract: A radiographic apparatus comprising, a radiation source for emitting radiation, a radiation detecting device having a detecting surface for detecting radiation, an image generating device for generating images in accordance with detection data outputted from the radiation detecting device, a collimator for restricting spread of a radiation beam emitted from the radiation source, an opening-degree obtaining device for obtaining a degree of opening of the collimator and a display device for displaying a radiation-irradiation area on the image, the opening-degree obtaining device determining the radiation-irradiation area to be displayed on the image in accordance with a relationship between a width of the radiation beam contained in the image obtained in advance by two or more degrees of opening of the collimator through radiation irradiation and the degrees of opening of the collimator as well as the current degree of opening of the collimator.Type: GrantFiled: November 16, 2012Date of Patent: January 5, 2016Assignee: SHIMADZU CORPORATIONInventors: Masahiro Tanaka, Takanori Yoshida
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Patent number: 9230322Abstract: According to some embodiments, an image processor includes an image acquirer, a first image generator, a point acquirer, a detector, a calculator and a determiner. The detector detects a second plurality of points in the first perspective images or the second perspective images corresponding to the first plurality of points. The calculator calculates, based on at least the first plurality of points and the second plurality of points, a difference in position of the target between when the first perspective images were captured and when the second perspective images were generated. The determiner determines whether or not the difference is in a range. If the difference is not in the range, then the first image generator generates updated ones of the second perspective images from an updated one of the volume data, which is different by the difference from a previous one of the volume data.Type: GrantFiled: April 2, 2015Date of Patent: January 5, 2016Assignee: Kabushiki Kaisha ToshibaInventors: Ryusuke Hirai, Yukinobu Sakata, Yasunori Taguchi, Takeshi Mita
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Patent number: 9227083Abstract: A method and a device for regulating a therapeutic beam directed at an object are provided. The method includes displaying at least one multidimensional image data record encompassing at least one target area of the object. The method also includes determining the treatment beam dosage directed at the at least one target area, and recording and optionally visualizing an isoline or isosurface dependent on the treatment beam dosage in the at least one multidimensional image data record. The method includes adjusting the isoline or isosurface such that the isoline or isosurface approximates a contour of the target area as closely as possible or corresponds to the contour, and regulating the treatment beam dosage by evaluation of the adjusted isoline or isosurface.Type: GrantFiled: September 26, 2012Date of Patent: January 5, 2016Assignee: Siemens AktiengesellschaftInventors: Mark Hastenteufel, Iwan Kawrakow, Christian Scholz
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Patent number: 9227085Abstract: An inverse planning method that is capable of controlling the appearance of the implanted fiducial(s) in segmented IMRT fields for cine MV or combined MV/kV image-guided IMRT is provided. The method for radiation treatment includes computing a radiation treatment plan and delivering beams to a target in accordance with the radiation treatment plan, where computing the radiation treatment plan includes introducing a penalty in an inverse planning objective function optimization calculation to discourage or avoid blockage of one or more fiducials in optimized multi-leaf collimator (MLC) apertures.Type: GrantFiled: March 2, 2011Date of Patent: January 5, 2016Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Yunzhi Ma, Paul J. Keall, Lei Xing
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Patent number: 9227086Abstract: A method of performing microbeam radiosurgery on a patient whereby target tissue within a patient is irradiated with high energy electromagnetic radiation via one or more microbeam envelopes with photons having respective energy magnitudes in excess of 200 keV, and maximum defined beam widths sufficiently narrow to yield a biological damage width which does not exceed a predetermined value.Type: GrantFiled: June 8, 2012Date of Patent: January 5, 2016Assignee: VARIAN MEDICAL SYSTEMS, INC.Inventor: Michael Dean Wright
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Patent number: 9220920Abstract: The therapeutic treatment of a patient using intensity-modulated proton therapy is described. In one example, a method of creating a proton treatment plan is presented that divides volumes of interest into sub-volumes, applies dose constraints to the sub-volumes, finds one or more feasible configurations of a proton therapy system, and selects a proton beam configuration that improves or optimizes one or more aspects of proton therapy. In some implementations, the method of dividing volumes into sub-volumes includes creating fractional sub-volumes based at least in part on proximity to a target volume boundary. In some implementations, the method of finding an improved or optimal proton beam configuration from a set of feasible configurations includes finding a minimum of a cost function that utilizes weighting factors associated with treatment sites.Type: GrantFiled: February 3, 2014Date of Patent: December 29, 2015Assignee: Loma Linda University Medical CenterInventors: Reinhard W. Schulte, Yair Censor
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Patent number: 9211423Abstract: A radiotherapy treatment device comprising an image acquisition device, in particular a magnetic resonance device, an irradiation device comprising in particular a linear accelerator, and a patient positioning device having a patient positioning platform, wherein a movement device is provided for jointly moving the image acquisition device and the irradiation device between an irradiation position, in which a radiotherapeutic treatment of a patient located on the patient positioning platform is possible by means of the irradiation device, and an image acquisition position, in which an image acquisition of the patient located on the patient positioning platform is possible by means of the image acquisition device is provided. A radiotherapy method for treating an irradiation target in a patient by means of such a radiotherapy treatment device is also disclosed.Type: GrantFiled: March 20, 2014Date of Patent: December 15, 2015Assignee: SIEMENS AKTIENGESELLSCHAFTInventors: Patrick Gross, Annemarie Hausotte, Björn Heismann, Sebastian Schmidt
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Patent number: 9205280Abstract: The present invention relates to method for generating planning data or control data for a radiation treatment, comprising the following steps: acquiring segmented data of an object which contains a treatment volume and a non-treatment volume; modelling at least some or all of the volume or surface of the treatment volume as a source of light or rays exhibiting a predefined or constant initial intensity; modelling the non-treatment volume as comprising volumetric elements or voxels which each exhibit an individually assigned feature or attenuation or transparency value (tmin?t?tmax) for the light or rays which feature is assigned to the light or ray or which attenuation or transparency maintains or reduces the intensity of the light or ray as it passes through the respective volumetric element or voxel, wherein the feature or attenuation or transparency value is individually assigned to each volumetric element or voxel of the non-treatment volume; defining a map surface which surrounds the treatment volume orType: GrantFiled: May 25, 2011Date of Patent: December 8, 2015Assignee: Brainlab AGInventors: Pascal Bertram, Claus Promberger, Thomas Flurschuetz
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Patent number: 9199093Abstract: The present invention relates to a device and method for verification of the quality of a radiation beam in conformal radiation therapy, and in particular for IMRT (Intensity Modulated Radiation Therapy) applications. The actual 3D dose distribution in the patient is tracked during the course of the entire treatment by reconstructing the photon fluences from measured 2D detector responses during irradiation in conjunction with updated patient images.Type: GrantFiled: May 6, 2009Date of Patent: December 1, 2015Assignee: Ion Beam Applications S.A.Inventor: Caterina Brusasco
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Patent number: 9192781Abstract: A radiotherapy system has: a placing unit placing a subject; an imaging unit performing an imaging of the subject; a region setting unit setting a required region of first image data obtained by the imaging unit performing the imaging of the subject and setting a corresponding required region of second image data obtained by, before the imaging, performing a pre-imaging of the subject; a histogram generating unit generating a dose-volume histogram of the required region of the first image data and generating a dose-volume histogram of the required region of the second image data; a difference computing unit computing a difference between the dose-volume histogram of the required region of the first image data and the dose-volume histogram of the required region of the second image data; and an outputting unit, if it is determined that the difference is greater than a threshold value, outputting the determination to an outside.Type: GrantFiled: April 27, 2012Date of Patent: November 24, 2015Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA MEDICAL SYSTEMS CORPORATIONInventors: Masahide Ichihashi, Masanori Koyama
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Patent number: 9168007Abstract: A computer aided diagnostic system according to the invention is characterized in that first sick portion detecting means for detecting a sick portion candidate based upon an image acquired by a first modality, second sick portion detecting means for detecting a sick portion candidate based upon an image related to the same region of interest of the same subject and acquired by a second modality different from the modality, detection result synthesizing means for comparing the results of detection by the first and second sick portion detecting means and correspondence displaying means for relating the position of the sick portion candidate detected by the first sick portion detecting means on an image analyzed by the second sick portion detecting means and displaying it and for relating the position of the sick portion candidate detected by the second sick portion detecting means on an image analyzed by the first sick portion detecting means and displaying it are provided.Type: GrantFiled: December 2, 2003Date of Patent: October 27, 2015Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA MEDICAL SYSTEMS CORPORATIONInventors: Masahiro Ozaki, Itsuko Iwata
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Patent number: 9155910Abstract: This invention relates to adaptive resistance inhibiting 100 to 1,000 Gy, single fraction radiosurgery with inverse Compton scattering gamma ray microbeam and nanobeam. The distance from two adjacent microbeams or the nanobeam generate peak and valley dose. Proliferation of normal tissue's clonogenic cells from low or no dose valley region to peak dose regions makes the normal tissue tolerance to to 100 to 1,000 Gy. The collilinear electron beam and gamma ray microbeam and nanobeam are generated in microfocus carbon tubes in a tissue equivalent primary collimator. Electron beam is absorbed by the tissue equivalent primary collimator. Focusing anode and magnets and multiwalled carbon nanotubes channels the microbeam and nanobeam as focused beams. Methods of spread out or spot scanned or raster scanned collilinear gamma ray microbeam and nanobeam radiosurgery are implemented. Adaptive resistance to cancer treatment is inhibited by inactivation of cancer cell's repair capabilities.Type: GrantFiled: January 16, 2013Date of Patent: October 13, 2015Inventor: Velayudhan Sahadevan
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Patent number: 9149655Abstract: The invention is directed to a method for controlling a process of monitoring the position of at least a part of a patient's body (1) during a radiation treatment, the method comprising the following steps: a) providing an energy value which is dependent on the radiation energy applied to the patient's body (1); b) controlling the time at which the monitoring process is performed, in accordance with the energy value.Type: GrantFiled: March 26, 2010Date of Patent: October 6, 2015Assignee: Brainlab AGInventors: Stefan Vilsmeier, Stephan Erbel