Therapy Patents (Class 378/65)
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Patent number: 9782607Abstract: Systems and methods for radiation treatment planning that integrate the MV therapeutic radiation dose imparted to a subject together with the kV imaging radiation dose imparted to a subject during radiation therapy are provided. For instance, dose optimization is based on the combined effect of both a kV imaging dose that is imparted to the subject during the image guided radiation treatment procedure and the therapeutic dose delivered to the subject by a treatment radiation source, such as an MV source. Using this optimization, the kV beam and MV beam are equally treated as radiation producing sources and are thus optimized together at the treatment planning stage to produce a patient treatment plan that optimally uses the kV imaging dose. Thus, the kV beam is treated both as an additional source of therapeutic radiation and as a tool for imaging the subject.Type: GrantFiled: August 5, 2015Date of Patent: October 10, 2017Assignee: The University of ChicagoInventors: Rodney Wiersma, Zachary Grelewicz
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Patent number: 9764162Abstract: Systems and methods can include obtaining computerized physician intent data representing an initial patient care plan; creating a computerized workflow to include a course of multiple radiation therapy sessions; performing instructions on the oncology computer system to generate control parameters for a radiation therapy apparatus to provide the radiation treatment in accordance with the workflow during the course of sessions; obtaining computerized treatment data after initiating the course of sessions; processing the computerized treatment data, using the processor circuit, to determine an indication of delivery or effect of the radiation treatment during the course of sessions based on the initial patient care plan relative to the workflow; using the indication of delivery or effect of the radiation treatment to adapt the patient care plan; and managing the workflow for the patient using the adapted patient care plan as the patient proceeds through a course of sessions.Type: GrantFiled: October 27, 2014Date of Patent: September 19, 2017Assignee: Elekta, Inc.Inventors: Virgil Matthew Willcut, Richard Henry Stark
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Patent number: 9757589Abstract: A method for determining a radiation therapy dose distribution includes selecting a treatment type from a database. An organ at risk (OAR) distance to target map is determined. The OAR distance to target map includes distances to a target organ for respective portions of an OAR, and the OAR distances are determined from a segmented patient organ image. A cohort average dose distance to target histogram is selected from the database. Dose values to the portions of the OAR are assigned to form a first 3D dose distribution map, where the dose values are from the selected cohort average dose distance to target histogram. A second 3D dose distribution map is determined based on a field arrangement determined by the treatment type, and the first 3D dose distribution map. A dose distance to target histogram is calculated using the second 3D dose distribution map and the distance to target map.Type: GrantFiled: April 13, 2016Date of Patent: September 12, 2017Assignee: Varian Medical Systems, Inc.Inventor: Corey Zankowski
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Patent number: 9753111Abstract: A system and method determines an isocenter for an imaging scan. The method includes receiving, by a control panel, patient data generated by at least one sensor, the patient data corresponding to dimensions of a body of a patient. The method includes generating, by the control panel, model data as a function of the patient data, the model data representing the body of the patient. The method includes receiving, by the control panel, a target location on the model data, the target location corresponding to a desired position on the body of the patient for performing the imaging scan. The method includes determining, by the control panel, an isocenter for the imaging scan as a function of the target location.Type: GrantFiled: June 7, 2014Date of Patent: September 5, 2017Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Peter Forthmann, Sascha Krueger, Tim Nielsen, Jurgen Erwin Rahmer, Peter Vernickel, Peter Boernert, Ulrich Katscher
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Patent number: 9744725Abstract: Methods and systems are disclosed for preserving thin components for three dimensional (3D) printing. An exemplary method generates a medial axis of a 3D shape and identifies components of the 3D shape that need to be preserved by applying a transform to the medial axis. The method creates an output model based at least in part on the components and an insetted shape corresponding to the 3D shape. A system includes a computing device with a processor and a memory having instructions that, if executed, cause the processor to perform operations. The operations comprise generating a medial axis of a 3D shape and applying a transform to the medial axis to identify one or more components of the shape to be preserved. The operations further comprise creating an output model based at least in part on the one or more components and an insetted shape corresponding to the 3D shape.Type: GrantFiled: September 5, 2013Date of Patent: August 29, 2017Assignee: Adobe Systems IncorporatedInventor: Ondrej Stava
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Patent number: 9743896Abstract: The present invention provides a method, including: obtaining a first image from a first imaging modality; identifying on the first image from the first imaging modality obtaining a second image from a second imaging modality; generating a compatible virtual image from the first image from the first imaging modality; mapping planning data on the compatible virtual image; coarse registering of the second image from the second imaging modality to the first image from the first imaging modality; identifying at least one element of the mapped planning data from the compatible virtual image; identifying at least one corresponding element on the second imaging modality; mapping the at least one corresponding element on the second imaging modality; fine registering of the second image from the second imaging modality to the first image from the first imaging modality; generating a third image.Type: GrantFiled: January 6, 2015Date of Patent: August 29, 2017Assignee: Body Vision MedicalInventor: Dorian Averbuch
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Patent number: 9744379Abstract: A treatment planning system (106) for generating patient-specific treatment margins. The system (106) includes one or more processors (142). The processors (142) are programmed to receive a radiation treatment plan (RTP) for irradiating a target (122) over the course of one or more treatment fractions. The RTP including one or more treatment margins around the target (122) and a planned dose distribution for the target (122). The processors (142) are further programmed to receive motion data for at least one of the treatment fractions of the RTP from one or more target surrogates (124), calculate a motion-compensated dose distribution for the target (122) using the motion data and the planned dose distribution, compare the motion-compensated dose distribution to the planned dose distribution, and adjust the treatment margins based on dosimetric differences between the motion-compensated dose distribution and the planned dose distribution.Type: GrantFiled: March 13, 2012Date of Patent: August 29, 2017Assignees: KONINKLIJKE PHILIPS N.V., WASHINGTON UNIVERSITYInventors: Shyam Bharat, Karl Antonin Bzdusek, Parag Jitendra Parikh, Camille Elizabeth Noel
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Patent number: 9731148Abstract: A system and method of delivering a radiation therapy treatment plan to a patient. The treatment plan is delivered using a radiation therapy system including a moveable support for supporting a patient, a gantry moveable relative to the support and supporting a radiation source and multi-leaf collimator for modulating the radiation source. The support and gantry are moved during delivery of the treatment plan.Type: GrantFiled: July 21, 2006Date of Patent: August 15, 2017Assignee: TOMOTHERAPY INCORPORATEDInventors: Gustavo H. Olivera, Thomas R. Mackie, Kenneth J. Ruchala, Paul J. Reckwerdt, John H. Hughes, Jeffrey M. Kapatoes, Eric Schnarr, Weiguo Lu, Eric Schloesser, Gerald D. Fordyce, II, Tim Holzmann
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Patent number: 9731147Abstract: Optimization of a radiation-delivery treatment plan can be facilitated by permitting the making of automatic changes to one or more treatment objectives. This can comprise processing radiation-delivery treatment plan parameters with respect to one or more predetermined treatment objectives and then automatically changing that predetermined treatment objective to provide one or more changed treatment objectives (including altered, deleted, and/or added treatment objectives) that can then be used to at least attempt to optimize a radiation-delivery treatment plan. That predetermined treatment objective can comprise, for example, a treatment objective as regards a given treatment volume. The automatic changing of the predetermined treatment objective can occur in response to a variety of stimuli such as detecting a change with respect to a treatment condition such as a change in the presentation of a patient volume of interest.Type: GrantFiled: February 7, 2012Date of Patent: August 15, 2017Assignee: Varian Medical Systems International AGInventors: Janne Nord, Juha Kauppinen, Lauri Halko, Jarkko Peltola
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Patent number: 9724049Abstract: A radiotherapy system acquires an image which is necessary for positioning of a patient for radiation treatment and enables grasping of a positional relationship of a target in a treatment radiation irradiated state, a radiation passing area and a critical organ. An X-ray imaging device is attached to the rotatable support device and configured to apply X-rays to the subject from plural directions while rotating around the subject to perform X-ray imaging. A target recognizing device recognizes a three-dimensional position of the target in the subject from X-ray images acquired by the X-ray imaging device; and CT image generating devices are configured to select, from the X-ray images acquired by the X-ray imaging device, the images in which the position of the target recognized by the recognizing device satisfies the treatment radiation irradiation condition for the motion tracking treatment to perform image reconstruction and generate a cone beam CT image.Type: GrantFiled: August 4, 2014Date of Patent: August 8, 2017Assignee: Hitachi, Ltd.Inventors: Toru Umekawa, Kazuo Hiramoto, Rika Baba, Toshie Sasaki, Yoshihiko Nagamine, Shinichi Shimizu, Seishin Takao, Naoki Miyamoto, Taeko Matsuura, Kikuo Umegaki
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Patent number: 9706969Abstract: According to one embodiment, a medical image diagnosis apparatus is capable of imaging a subject based on a scan plan. The medical image diagnosis apparatus includes a gantry, a bed, a display, and a controller. The gantry images the subject. The bed includes a top-plate upon which the subject is positioned. The display is attached to the gantry. The controller displays, based on the scan plan, one of a moving distance of the top-plate, a moving direction of the top-plate, and a scan mode based on the scan plan.Type: GrantFiled: May 13, 2015Date of Patent: July 18, 2017Assignee: Toshiba Medical Systems CorporationInventor: Koji Takei
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Patent number: 9700738Abstract: The present invention concerns a radiation inverse treatment planning system for a linear accelerator. The system includes a radiation source, configured for delivering individual radiotherapeutic dose shots (aj), each individual radiotherapeutic dose shot having a predetermined location and incidence angle inside and/or outside a target area, a size and a shape. The system also includes at least a data bus system (102), and a memory (106) coupled to the data bus system (102), wherein the memory (106) includes a computer usable program code. The system also includes a processing unit (104) coupled to the data bus system (102), wherein the processing unit (104) is configured to execute the computer usable program code to pre-compute (10) a set of individual radiotherapeutie dose shots (aj), and associate (40) a weight (sj) to each individual radiotherapeutic dose shot (aj), based on one or more constraints (20).Type: GrantFiled: June 27, 2014Date of Patent: July 11, 2017Assignee: Intuitive Therapeutics SAInventors: Andre Martin, Daniel Salzmann
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Patent number: 9700739Abstract: The present invention concerns an inverse treatment planning system. The system includes, at least a data bus system (102), a memory (106) coupled to the data bus system (102), and a processing unit (104) coupled to the data bus system (102). The processing unit (104) is configured to execute the instructions to pre-compute (10) a set of individual dose shots (aj), each individual dose shot having a predetermined location inside and/or outside a target area, a size and a shape. The processing unit also associates (40) a weight (sj) to each individual dose shot (aj), based on one or more constraints (20). The processing unit (104) further executes the instructions to find (30) the sparsest subset of individual dose shots, so as to satisfy said one or more constraints (20).Type: GrantFiled: June 27, 2014Date of Patent: July 11, 2017Assignee: Intuitive Therapeutics SAInventors: Andre Martin, Daniel Salzmann
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Patent number: 9694205Abstract: Radiotherapy apparatus comprises a source of radiation mounted on a chassis, that is rotatable about a rotation axis and the source being adapted to emit a beam of radiation along a beam axis; a patient support, moveable along a translation axis; a set of magnetic coils located on either side of the beam, for establishing a magnetic field along a first direction; the translation axis, the rotation axis, and the first direction being substantially parallel; and further comprising a multi-leaf collimator fixed in its orientation with respect to the source of radiation, the multi-leaf collimator comprising a plurality of elongate leaves disposed with their longitudinal directions substantially aligned with the first direction and movable in that direction between a withdrawn position in which the leaf lies outside the beam, an extended position in which the leaf projects across the beam.Type: GrantFiled: February 12, 2010Date of Patent: July 4, 2017Assignee: ELEKTA AB (PUBL)Inventors: John Allen, Duncan Neil Bourne, Kevin John Brown
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Patent number: 9687673Abstract: Systems for delivering radiation dose to a target area within a subject comprise: a radiation source for outputting a radiation beam; a support for supporting the subject; a movement mechanism for moving the radiation source relative to the subject along a trajectory; and a controller configured to cause, according to a radiation delivery plan: the radiation source to deliver the radiation beam to the subject while causing the movement mechanism to effect relative movement between the radiation source and the subject along the trajectory; and the radiation source to vary an intensity of the radiation beam by varying a radiation output rate of the radiation source according to the radiation delivery plan over at least a portion of the trajectory while causing the movement mechanism to effect relative movement between the radiation source and the subject, to thereby deliver dose to the subject according to the radiation delivery plan.Type: GrantFiled: September 15, 2016Date of Patent: June 27, 2017Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 9687678Abstract: Systems for planning delivery of radiation dose to a target region within a subject comprise a processor configured to: initialize a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a radiation source and the subject, wherein initializing the first plurality of control points comprises assigning, to each the first plurality of control points, one or more axis positions which specify a position of the radiation source relative to the subject; specify a second plurality of control points along the trajectory, the second plurality of control points comprising a larger number of control points than the first plurality of control points; and iteratively optimize a simulated dose distribution over the second plurality of control points to thereby determine a radiation delivery plan by assigning each of the second plurality of control points optimized values for one or more radiation delivery parameters.Type: GrantFiled: September 15, 2016Date of Patent: June 27, 2017Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 9687676Abstract: Systems for planning delivery of radiation dose to a target region within a subject comprise a processor configured to: iteratively optimize a simulated dose distribution relative to a set of one or more optimization goals comprising a desired dose distribution in the subject over a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a treatment radiation source and the subject; reach one or more initial termination conditions, and after reaching the one or more initial termination conditions: specify a second plurality of control points along the trajectory, the second plurality of control points comprising a larger number control points than the first plurality of control points; and iteratively optimize a simulated dose distribution relative to the set of one or more optimization goals over the second plurality of control points to thereby determine a radiation delivery plan.Type: GrantFiled: September 15, 2016Date of Patent: June 27, 2017Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 9687674Abstract: Systems for delivering radiation dose to a target area within a subject comprise: a radiation source for outputting a radiation beam; a support for supporting the subject; a movement mechanism for moving the radiation source relative to the subject along a trajectory; one or more sensors for monitoring a position of the subject; and a controller configured, in accordance with a radiation delivery plan, to: determine the position from one or more signals received from the one or more sensors; deactivate delivery of the treatment radiation beam upon determining that the position is outside of an acceptable range; and reactivate delivery of the treatment radiation beam upon determining that the position is within the acceptable range, to thereby deliver dose to the subject according to the radiation delivery plan.Type: GrantFiled: September 15, 2016Date of Patent: June 27, 2017Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 9687677Abstract: Methods for planning delivery of radiation dose to a target region within a subject comprise: initializing a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a radiation source and the subject, wherein initializing the first plurality of control points comprises assigning, to each the first plurality of control points, one or more axis positions which specify a position of the radiation source relative to the subject; specifying a second plurality of control points along the trajectory, the second plurality of control points comprising a larger number of control points than the first plurality of control points; and iteratively optimizing a stimulated dose distribution over the second plurality of control points to thereby determine a radiation delivery plan by assigning each of the second plurality of control points optimized values for one or more radiation delivery parameters.Type: GrantFiled: September 15, 2016Date of Patent: June 27, 2017Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 9687200Abstract: Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a ring gantry having a central opening and a radiation treatment head coupled to the ring gantry that is rotatable around the central opening in at least a 180 degree arc. For one preferred embodiment, the apparatus further comprises a gantry translation mechanism configured to translate the ring gantry in a direction of a longitudinal axis extending through the central opening. Noncoplanar radiation treatment delivery can thereby be achieved without requiring movement of the patient. For another preferred embodiment, an independently translatable 3D imaging device distinct from the ring gantry is provided for further achieving at least one of pre-treatment imaging and setup imaging of the target tissue volume without requiring movement of the patient.Type: GrantFiled: April 15, 2011Date of Patent: June 27, 2017Assignee: Accuray IncorporatedInventor: Calvin R. Maurer, Jr.
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Patent number: 9687675Abstract: Methods for planning delivery of radiation dose to a target region within a subject comprise: iteratively optimizing a simulated dose distribution relative to a set of one or more optimization goals comprising a desired dose distribution in the subject over a first plurality of control points located on a trajectory, the trajectory comprising relative movement between a radiation source and the subject; reaching one or more initial termination conditions, and after reaching the one or more initial termination conditions: specifying a second plurality of control points along the trajectory and comprising a larger number control points than the first plurality of control points; and iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over the second plurality of control points to thereby determine a radiation delivery plan.Type: GrantFiled: September 15, 2016Date of Patent: June 27, 2017Assignee: Varian Medical Systems International AGInventor: Karl Otto
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Patent number: 9684982Abstract: A computer-implemented method for performing isotropic reconstruction of Magnetic Resonance Imaging (MRI) data includes receiving a stack of slices acquired by an MRI device in two or more directions and reslicing the stack of slices into (i) an acquired view stack comprising high-resolution slices acquired in-plane, and (ii) a reslice stack comprising degraded slices acquired out of plane. An estimated slice profile is generated based on the stack of slices and the acquired view stack is convolved with the estimated slice profile to yield a simulated distorted slice stack. The simulated distorted slice stack is subtracted from the acquired view stack to yield a high-frequency band estimate and the high-frequency band estimate is combined with the reslice stack to yield isotropic reconstruction results.Type: GrantFiled: September 1, 2015Date of Patent: June 20, 2017Assignee: Siemens Healthcare GmbHInventors: Ti-chiun Chang, Xiaoguang Lu, Peter Speier
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Patent number: 9679110Abstract: Embodiments develop a predictive dose-volume relationships for a radiation therapy treatment is provided. A system includes a memory area for storing data corresponding to a plurality of patients, wherein the data comprises a three-dimensional representation of the planning target volume and one or more organs-at-risk. The data further comprises an amount of radiation delivered to the planning target volume and the one or more organs-at-risk. The system further includes one or more processors programmed to access, from the memory area, the data and to develop a model that predicts dose-volume relationships using the three-dimensional representations of the planning target volume and the one or more organs-at-risk. The model is being derived from correlations between dose-volume relationships and calculated minimum distance vectors between discrete volume elements of the one or more organs-at-risk and a boundary surface of the planning target volume.Type: GrantFiled: June 1, 2012Date of Patent: June 13, 2017Assignee: Washington UniversityInventors: Kevin L. Moore, Sasa Mutic, Ryan Scott Brame, Lindsey Appenzoller
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Patent number: 9662016Abstract: A method for automatically adding a first sensor device to a first personal area network in a healthcare application includes receiving a signal with out-of-band pairing data at the first sensor device. The first sensor device is disposed on a patient's body. The out-of-band pairing data is injected into the patient's body by a second sensor device disposed on the patient's body. Pairing data is extracted from the received signal at the first sensor device. Using the pairing data, the first sensor device is added to the first personal area.Type: GrantFiled: October 24, 2016Date of Patent: May 30, 2017Assignee: Welch Allyn, Inc.Inventors: Steven D. Baker, Robert J. Kahlke
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Patent number: 9655585Abstract: An X-ray diagnostic apparatus includes a first support mechanism supporting a first X-ray tube which irradiates an object with first X-rays along a first direction, a second support mechanism supporting a second X-ray tube which irradiates the object with second X-rays along a second direction different from the first direction, a dose distribution generation unit generates a first and second dose distribution corresponding to the first and second X-rays respectively, a specifying unit specifying position states of the first and second support mechanism and operation states of the first and second X-ray tube, a display unit simultaneously displaying, with at least two different viewpoints in accordance with the position states and the operation states, a model on which the first and second dose distribution are superimposed.Type: GrantFiled: September 25, 2014Date of Patent: May 23, 2017Assignee: Toshiba Medical Systems CorporationInventors: Yuichiro Watanabe, Takuya Sakaguchi, Masanori Matsumoto
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Patent number: 9649508Abstract: Methods, systems and computer-readable storage media relate to determining individualized treatment planning margins. The methods may include processing motion data of a target obtained from at least one marker for one or more periods. Each period may include a plurality of time intervals. The processing may include processing the motion data to determine an isocenter for each time interval along at least one of the axes of motion. The axes can include the x axis, the y axis, and/or the z axis. The method may include determining motion prediction data for each of the at least one of the axes; and determining treatment planning margins for each of the at least one of the axes based on the motion prediction data. The individualized treatment margins can be smaller and more optimal because the treatment margins can incorporate patient specific patterns of motion of a target (e.g., an organ).Type: GrantFiled: September 13, 2013Date of Patent: May 16, 2017Assignees: Emory University, University of Tennessee Research FoundationInventors: Mohammad Khurram Khan, Michael Edward Howard, Laurence F. Miller
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Patent number: 9630023Abstract: The present invention is a method and system for developing a dynamic scheme for Gamma Knife radiosurgery based on the concept of “dose-painting” to take advantage of robotic patient positioning systems on the Gamma Knife C and Perfexion units. The spherical high dose volume created by the Gamma Knife unit will be viewed as a 3D spherical “paintbrush”, and treatment planning is reduced to finding the best route of this “paintbrush” to “paint” a 3D tumor volume. Under the dose-painting concept, Gamma Knife radiosurgery becomes dynamic, where the patient is moving continuously under the robotic positioning system.Type: GrantFiled: December 16, 2013Date of Patent: April 25, 2017Assignee: STC.UNMInventors: Shuang Luan, Nathan Swanson, Lijun Ma
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Patent number: 9630026Abstract: The present invention relates to a data processing method for determining control data for controlling beam positions which beam positions describe positions which a treatment beam has or would have if emitted by a beam source, the treatment beam being for treating a treatment body part of a patient, said method constituted to be performed by a computer and comprising the steps of: • providing treatment data which comprise data on a position of the treatment body part; • providing condition data which describe: constraints on the beam positions and/or constraints on positional changes of the beam positions, wherein said constraints allow for at least a part of the beam positions to lie not in a common plane; • providing an arrangement of the beam positions on the basis of the treatment data which arrangement fulfils the condition data; • determining control data for controlling a change of a relative position of the beam source relative to the treatment body part for changing the beam positions and for controType: GrantFiled: July 23, 2010Date of Patent: April 25, 2017Assignee: Brainlab AGInventors: Stephan Froehlich, Franz Gum, Kajetan Berlinger
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Patent number: 9622717Abstract: Methods and systems are provided that obtain a scan prescription and receive physiologic feature or interest (FOI) measurements of an object of interest during a scan time. The methods and systems further compare at least one of the received physiologic FOI measurements with a predetermined threshold range, and determine a scan setting by evaluating an acquisition rule set based on the physiologic FOI measurement.Type: GrantFiled: December 18, 2014Date of Patent: April 18, 2017Assignee: General Electric CompanyInventors: John Howard Londt, Roy A. Nilsen, Holly Ann McDaniel, Scott D. Slavic, John Irvin Jackson, Elizabeth Nett, Ann Soderman, Victor Eduardo McCormack
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Patent number: 9616249Abstract: A radiotherapy control apparatus includes a fluoroscopic image acquisition unit to acquire fluoroscopic images of markers in a patient from a single fluoroscopic imaging device, a projection line calculation unit to identify projected positions of the markers on the fluoroscopic image and calculate equations of projection lines linking these projected positions and a focus position of the imaging device, an inter-marker distance acquisition unit to acquire a distance between each pair of the markers, a marker position calculation unit to calculate current positions of the markers based on the equations and the distances, and a therapeutic radiation emission determination unit to determine whether to emit therapeutic radiation based on the current positions of the markers.Type: GrantFiled: February 26, 2013Date of Patent: April 11, 2017Assignee: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventors: Naoki Miyamoto, Shinichi Shimizu, Taeko Matsuura, Chie Toramatsu, Seishin Takao, Hideaki Nihongi, Yuichi Hirata, Kikuo Umegaki
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Patent number: 9616250Abstract: According to an embodiment, a treatment system includes a plurality of first radiators, a plurality of detectors, a determiner, and a controller. Each of the first radiators irradiates a radioactive beam to a subject. Each of the detectors detects a radioactive beam transmitted through the subject and generates an image based on the detected radioactive beam. The determiner determines whether an object in the subject is included in a first region using a given image that is one of the images. The controller controls the first radiators so that, when the object is not included in the first region, a smaller amount of radioactive beams is irradiated per unit time than when the object is included in the first region.Type: GrantFiled: July 11, 2014Date of Patent: April 11, 2017Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Yasunori Taguchi, Takeshi Mita, Yukinobu Sakata, Tomoyuki Takeguchi
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Patent number: 9622333Abstract: A linac-based X-ray system for cargo scanning and imaging applications uses linac design, RF power control, beam current control, and beam current pulse duration control to provide stable sequences of interleaved pulses having different energy levels, for example alternating 4 MeV and 6 MeV pulses or other energies where the difference in levels is at least approximately 1 MeV and less than approximately 5 MeV. The pulse repetition rate can be 100-400 pulses per second or more. In an embodiment, a cool down calculation is combined with automatic frequency control to provide stable energy and dose per pulse even upon restarting of pulsing after an “off” period of indeterminate duration.Type: GrantFiled: February 27, 2014Date of Patent: April 11, 2017Assignee: ETM ELECTROMATIC, INCInventors: William L. Nighan, Jr., Maarten Korringa, John Howard Rolin, Devin Kirk Henderlong
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Patent number: 9616251Abstract: Systems, devices, and methods for imaging-based calibration of radiation treatment couch position compensations.Type: GrantFiled: July 25, 2014Date of Patent: April 11, 2017Assignees: VARIAN MEDICAL SYSTEMS, INC., VARIAN MEDICAL SYSTEMS INTERNATIONAL AGInventors: Reto W. Filiberti, Stephen Gaudio
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Patent number: 9604075Abstract: A method for calculating local part radiation doses in a radiotherapy system for applying a total radiation dose in a target volume with several beams is provided. The method includes determining at least one first control plane for controlling the dosing of the beams, determining at least one second control plane for controlling the positioning of the beams, and allocating beams to the first and second control planes. The method also includes, for at least one side of a first control plane, calculating in isolation of the corresponding local part radiation doses of all the beams allocated to the first control plane.Type: GrantFiled: November 23, 2012Date of Patent: March 28, 2017Assignee: Siemens AktiengesellschaftInventor: Christian Scholz
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Patent number: 9592408Abstract: A radiation planning system includes a dose volume kernel determiner (122) and an expected absorbed dose determiner (124). The dose volume kernel determiner (122) generates a dose volume kernel for each of a plurality of voxels in a dose calculation grid. Each of the dose volume kernels is based on a radial dose distribution and a template function for a particular voxel size. The expected absorbed dose determiner (124) determines an expected absorbed dose distribution for each of the plurality of voxels based on the dose volume kernel.Type: GrantFiled: March 20, 2009Date of Patent: March 14, 2017Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Bernd Schweizer, Andreas Goedicke
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Patent number: 9579526Abstract: Embodiments of the claimed subject matter provide a radiation therapy system for the acquisition of volumetric imaging with advanced trajectories. Embodiments include a device for applying diagnostic and therapeutic radiation to a target volume disposed in a patient subject, wherein volumetric imaging is acquired with advanced trajectories without displacing the patient subject. In one embodiment, a radiation therapy device is provided comprising: a gantry with a radiation source and a plurality of independent robotic arms mounted to the gantry, wherein an X-ray source is attached to an end of one robotic arm; and an imager attached to an end of another second robotic arm.Type: GrantFiled: February 2, 2009Date of Patent: February 28, 2017Assignee: Varian Medical Systems International AGInventors: Patrik Kunz, Timo Berkus, Markus Oelhafen, Reto Filiberti
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Patent number: 9561389Abstract: Photon-based radiosurgery is widely used for treating local and regional tumors. The key to improving the quality of radiosurgery is to increase the dose falloff rate from high dose regions inside the tumor to low dose regions of nearby healthy tissues and structures. Dynamic photon painting (DPP) further increases dose falloff rate by treating a target by moving a beam source along a dynamic trajectory, where the speed, direction and even dose rate of the beam source change constantly during irradiation. DPP creates dose gradient that rivals proton Bragg Peak and outperforms Gamma Knife® radiosurgery.Type: GrantFiled: June 10, 2016Date of Patent: February 7, 2017Assignee: STC.UNMInventors: Shuang Luan, Lijun Ma, Zhe Chen
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Patent number: 9526917Abstract: A radiotherapy apparatus comprises a rotatable gantry, supporting a source of therapeutic radiation and a source of diagnostic radiation. The two sources may be rotationally spaced apart around a rotation axis of the gantry, with at least one collimator associated with the source of therapeutic radiation and arranged to limit the cross-sectional area of a beam produced by that source. A control means may be arranged to conduct a treatment fraction using the apparatus by causing the apparatus to acquire images of a patient using the source of diagnostic radiation, retain those images at least temporarily, select a retained image acquired when the source of diagnostic radiation was at a rotational position corresponding to the instantaneous rotational position of the source of therapeutic radiation, and control the beam relative to the patient using information derived from the selected image.Type: GrantFiled: April 30, 2014Date of Patent: December 27, 2016Assignee: Elekta AB (Publ)Inventor: Per Carlsson
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Patent number: 9517358Abstract: A radiation beam, for example a therapeutic radiation beam such as an IMRT or VMAT X-ray beam is monitored using a Monolithic Active Pixel Sensor (MAPS) detector. Photons of the radiation beam can interact with the MAPS detector, and the radiation beam configuration can be estimated from the determined positions of the interactions. The detector is made sufficiently thin that it interacts only very weakly with the X-ray photons. For example, less than 1 in 103 of the X-ray photons might interact with the detector. Hence, the disturbance to the X-ray beam is negligible.Type: GrantFiled: December 21, 2011Date of Patent: December 13, 2016Assignee: THE UNIVERSITY OF BRISTOLInventors: Jaap Velthuis, Peter Richard Hugtenburg, Catherine Hall, Ryan Page, Paul Stevens
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Patent number: 9504854Abstract: A rotating gantry is characterized in that a shielding material for attenuating a leakage dose of a secondary radiation generated by collision of a charged particle beam with an irradiation subject is provided at a position that is situated at the side opposed to a particle beam irradiation apparatus with respect to the irradiation subject and through which a beam axis of the charged particle beam passes, and wherein the shielding material is disposed in such a way that when the irradiation subject does not exist in the rotating gantry, a beam axis portion thereof that intersects the beam axis of the charged particle beam, is attachable and detachable, or can move in a sliding manner and in the rotation-axle direction of the rotating gantry.Type: GrantFiled: March 29, 2012Date of Patent: November 29, 2016Assignee: MITSUBISHI ELECTRIC CORPORATIONInventor: Tadashi Katayose
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Patent number: 9507886Abstract: A novel and powerful fluence and beam orientation optimization package for radiotherapy optimization, called PARETO (Pareto-Aware Radiotherapy Evolutionary Treatment Optimization), makes use of a multi-objective genetic algorithm capable of optimizing several objective functions simultaneously and mapping the structure of their trade-off surface efficiently and in detail. PARETO generates a database of Pareto non-dominated solutions and allows the graphical exploration of trade-offs between multiple planning objectives during IMRT treatment planning PARETO offers automated and truly multi-objective treatment plan optimization, which does not require any objective weights to be chosen, and therefore finds a large sample of optimized solutions defining a trade-off surface, which represents the range of compromises that are possible.Type: GrantFiled: June 7, 2011Date of Patent: November 29, 2016Inventors: Jason Fiege, Boyd McCurdy, Peter Potrebko, Andrew Cull, Heather Champion, Murphy Berzish
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Patent number: 9504850Abstract: Preparing a plan to synchronize radiation delivery to a target in a patient with patient breathing phase and amplitude as the independent variable comprising (a) obtaining simultaneous data on patient breathing and target shape and location, (b) correlating the data and optimizing the correlation, (c) establishing optimal parameters of radiation delivery for each breathing phase/amplitude or for each target shape/location; and (d) synchronizing radiation delivery to a target in a patient with patient breathing comprising (a) positioning the patient, (b) monitoring actual breathing or the shape/location of the target, and (c) while monitoring, delivering radiation to the target according to a plan; and a system for controlling radiation delivery by a device to a target in a patient comprising (i) a processor, which receives and processes data on breathing or the shape/location of the target, and (ii) a controller, which controls radiation delivery to the target according to a plan, which synchronizes radiationType: GrantFiled: March 9, 2014Date of Patent: November 29, 2016Assignee: XCISION MEDICAL SYSTEMS LLCInventors: Jin Zhang, Xinsheng Cedric Yu, Peter Maton
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Patent number: 9495513Abstract: The invention relates to a computer readable medium including software instructions, which when executed by a scaling parameters for processor perform a method. The method includes obtaining a first and a second pre-calculated history, wherein the first and the second pre-calculated history corresponds to a first and a second path of particles through a reference material. The method further includes obtaining a first and a second plurality of phase space points and performing a first and a second set of simulations in parallel on a first and a second GPU. Each simulation uses a distinct one of the first and second plurality of phase space points, the geometry information, and the first and second pre-calculated history. The sets of simulations are performed on the GPU's to obtain a set of simulated histories. The method further includes calculating an absorbed dose of energy in the target using the set of simulated histories.Type: GrantFiled: September 16, 2011Date of Patent: November 15, 2016Assignees: William Marsh Rice University, Board of Regents, The University of Texas SystemInventors: Pablo P. Yepes, Wayne David Newhauser, John Gordon Eley
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Patent number: 9486839Abstract: An apparatus and a method for sorting scrap metal containing at least two categories of metals are provided. An x-ray beam is directed towards at least a portion of a particle of scrap metal. Backscattered x-rays, forward scattered x-rays, and transmitted x-rays from the particle are measured and input into a classifier, such as a database with a cutoff plane. The scrap metal is sorted into a first category and a second category on the scrap metal by a controller. An x-ray source for a scanning system is provided with an electron beam generator, an electromagnetic beam focusing coil, a pair of saddle shaped beam steering coils, and a target foil to create a scanning x-ray beam along a plane.Type: GrantFiled: January 6, 2012Date of Patent: November 8, 2016Assignee: Huron Valley Steel CorporationInventors: Paul Torek, Daniel F. Gorzen, Kalyani Chaganti
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Patent number: 9486645Abstract: The present invention advantageously provides a method and system for providing accurately localized, non-invasive radiation treatment for ocular melanoma or other intraocular indications through the completion of specified research tasks. The present invention further provides for dynamic localization of tumors associated with such indications. The system of the present invention includes the CYBERKNIFE system, a robust eye pupil tracking system, and an integrated software package to achieve intra-beam fractional tumor tracking during radiation delivery. The system may further include a mechanical phantom incorporated with a radiation dosimetry calibration kit for validation.Type: GrantFiled: December 8, 2014Date of Patent: November 8, 2016Assignee: University of MiamiInventors: Xiaodong Wu, Weizhao Zhao
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Patent number: 9474913Abstract: A teletherapy treatment arrangement constituted of: a control unit; a 3 dimensional imager having an effective patient plane; at least one 2 dimensional imager arranged to provide a pair of 2 dimensional images along planes generally orthogonal to the effective patient plane of the 3 dimensional imager; and a patient positioner arranged to secure a target tissue in a fixed relationship to the patient positioner, the control unit arranged to: input a planned treatment position of the patient target tissue; in the event that the planned treatment position is consonant with the effective patient plane of the 3 dimensional imager, obtain position information of the target tissue from the 3 dimensional imager, and in the event that the planned treatment position is not consonant with the effective patient plane of the 3 dimensional imager, obtain position information of the target tissue from the at least one 2 dimensional imager.Type: GrantFiled: April 29, 2012Date of Patent: October 25, 2016Assignee: P-CURE, LTD.Inventor: Michael Marash
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Method and a system for optimizing a radiation treatment plan based on a reference dose distribution
Patent number: 9468776Abstract: A computer-based method for generating an improved radiation therapy treatment plan for a treatment volume having a target and an organ-at-risk. The method includes a step of accessing an existing radiation therapy treatment plan from a memory of a computer, a dose distribution of the existing radiation therapy treatment plan serving as a reference dose distribution; and performing machine parameter optimization on the existing radiation therapy treatment plan with the computer by pursuing an optimization goal to minimize doses to the organ-at-risk, thereby generating the improved radiation therapy treatment plan.Type: GrantFiled: June 1, 2012Date of Patent: October 18, 2016Assignee: RaySearch Laboratories ABInventor: Albin Fredriksson -
Patent number: 9462991Abstract: Systems and methods for remote diagnostic imaging. The systems include a diagnostic imaging kiosk. The kiosk includes, for example, a first housing module and a second housing module. The first housing module is configured to house, among other things, a diagnostic imaging system (e.g., an X-ray system). The second housing module is configured to house electronics associated with the operation, control, and networking of the kiosk. The electronics include, for example, a primary controller, an X-ray controller, an X-ray generator, an internal display controller, an external display controller, one or more routers, and a digital radiology module. The kiosk is configured to communicatively connect to a remote technician's workstation, and a remote technician at the workstation is able to remotely control the kiosk through a packet-switched network.Type: GrantFiled: September 3, 2013Date of Patent: October 11, 2016Assignee: Merge Healthcare IncorporatedInventor: Michael W. Ferro, Jr.
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Patent number: 9463336Abstract: A system for evaluating radiation treatment planning generates a fictitious treatment dose matrix with a quality of dose placement beyond that achievable with physically realizable radiation therapy machines. Such a fictitious treatment dose matrix provides an objective measure that is readily tailored to different clinical situations, and although unattainable, thereby provides a benchmark allowing evaluation of radiation plan goals and the radiation plans between different multiple clinical situations and individuals.Type: GrantFiled: October 11, 2013Date of Patent: October 11, 2016Assignee: Sun Nuclear CorporationInventor: Benjamin E. Nelms
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Patent number: 9451923Abstract: According to one embodiment, the x-ray apparatus comprises an x-ray source adapted to emit an x-ray beam, a detector adapted to receive the x-ray beam of the x-ray source, wherein the x-ray source is adapted to be moved in relation to a first portion of the x-ray apparatus, wherein the detector is adapted to be moved in relation to a first portion of the x-ray apparatus, the x-ray apparatus further comprising a control unit for controlling the movement of the x-ray source and detector, wherein the x-ray source and the detector are adapted to rotate in relation to a first portion of the x-ray apparatus, wherein further the x-ray beam is directed essentially towards the detector during the movement of the x-ray source and the detector.Type: GrantFiled: June 27, 2012Date of Patent: September 27, 2016Assignee: Koninklijke Philips N.V.Inventors: Magnus Hemmendorff, Torbjorn Hjarn, Mats Lundqvist, Jonas Rehn