Using Direct Contact With Electrical Or Electromagnetic Radiation Patents (Class 422/22)
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Patent number: 7632413Abstract: Devices and methods for treating, preventing from growth, and neutralizing hyperproliferative, undifferentiated, or virally infected cells in a liquid medium using high-frequency, low-energy ultrasound.Type: GrantFiled: November 4, 2003Date of Patent: December 15, 2009Assignee: Ashland Licensing and Intellectual Property LLCInventors: Eric D. Cordemans De Meulenaer, Baudouin Hannecart, Yves Canivet
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Patent number: 7626186Abstract: A mobile electron beam radiation sterilizing apparatus includes a movable chassis vehicle; a cabinet body installed on the chassis vehicle; an electron accelerator, which generates electron beam for articles to be radiation-processed, wherein the electron accelerator is provided in the cabinet body; an accelerator control box, which controls operation of the electron accelerator, a radiation shielding system comprised of: a stationary shielding body covering the electron accelerator; a pair of rotatable shielding doors, through which a passage is formed for an article to be processed to enter or exit, rotatably connected to the stationary shielding body; a motor for switching on and switching off the rotatable shielding doors.Type: GrantFiled: June 8, 2007Date of Patent: December 1, 2009Assignees: Tsinghua University, Nuctech Company LimitedInventors: Kejun Kang, Huayi Zhang, Zhiqiang Chen, Yuanjing Li, Chuanxiang Tang, Yaohong Liu, Huaibi Chen, Huaping Tang, Nan Jiang, Dongsheng Zhang, Yu He, Feng Gao, Weiqiang Guan, Jian Li, Yanfeng Cao
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Patent number: 7621985Abstract: An air purifier to improve air quality for breathing is disclosed. A magnetized torch module that passes a large air flow is designed. The emission spectroscopy of the torch indicates that the plasma effluent carries an abundance of reactive atomic oxygen (RAO), which can effectively kill all kinds of microbes. The invention employs two torch modules which run alternately to generate non-thermal plasma for air treatment via both thermal/non-thermal processes. The air flow through the on-torch module is mainly treated thermally. A controlling air valve is designed to direct the exiting airflow of the off-torch module to pass through the plasma torch of the on-torch module for non-thermal treatment. The controlling air valve also works to turn the torch modules on and off synchronizing with the closing and opening of the two air valves in the controlling air valve. This device purifies ambient air in a fast rate and kills microbes thoroughly.Type: GrantFiled: May 24, 2008Date of Patent: November 24, 2009Assignee: Adventix Technologies Inc.Inventor: Spencer P. Kuo
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Publication number: 20090285969Abstract: An improved pasteurisation protocol for pasteurising microbial cells is disclosed. The protocol has three stages, a first heating stage, a second plateau stage at which the cells are held at a (maximum and) constant temperature, and a third cooling stage. Both the heating and the cooling stages are rapid, with the temperature of the cells passing through 40 to 80° C. in no more than 30 minutes in the heating stage. The heating rate is at least 0.5° C./minute and during cooling is at least ?0.5° C./minute. The plateau maximum temperature is from 70 to 85° C. By plotting the pasteurisation protocol on a time (t, minutes) versus temperature (T, ° C.) graph, one obtains a trapezium having an area less than 13,000° C. minute. Not only does this result in a smaller energy input (and so a reduction in costs), but a better quality (and less oxidised) oil results having a peroxide value (POV) of less than 1.5 and an anisidine value (AnV) of less than 1.0.Type: ApplicationFiled: March 9, 2009Publication date: November 19, 2009Applicant: DSM IP ASSETS B.V.Inventors: Albert Schaap, Daniel Verkoeijen
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Publication number: 20090274576Abstract: Packaging materials and containers may be treated with sterilization dosages internally and externally using monochromatic, continuous wave, high-intensity, incoherent light in single and/or multiple light source configurations. The treatment systems and methods preserve physical and performance properties of the packaging/container while achieving a desired level of sterilization. The sterilized materials may be adapted for extended shelf life (ESL) products. The disclosed treatment systems and methods may also be used for sterilization of food and beverage products (either prepackaged or post packaged), medicines, pharmaceuticals, vitamins, infusion products, clinical and/or non-clinical solutions and systems, enteral and/or parenteral solutions and systems, and the like.Type: ApplicationFiled: January 17, 2007Publication date: November 5, 2009Inventor: Barry Ressler
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Publication number: 20090269240Abstract: A fluid purification device capable of exerting high disinfection/purification functions by a simple structure is provided, and a fluid purification device capable of suppressing, for example, generation of noise and high-voltage charging upon disinfection/purification of a fluid to be treated composed of liquid such as water is provided.Type: ApplicationFiled: December 18, 2006Publication date: October 29, 2009Inventor: Toshiharu Tanaka
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Publication number: 20090257910Abstract: A system for disinfecting an intravenous catheter and/or other fluidic tubing includes attaching a device around the catheter and delivering a high dose of ultraviolet or other type of radiation to the catheter connection point and adjacent tubing. The device may include a UV radiation source connected to a catheter attachment assembly via fiber optic cable, allowing transmission of UV radiation from the source to an internal reflector unit. The UV source may be built into the catheter connection assembly. The device may be a handheld device that fits over a catheter connection point, with single or multiple integrated UV sources to deliver 360 degree radiation around the catheter, with mirrors to increase light delivery. The method involves controlled exterior irradiation of a catheter connection point to disinfect the lumen via transmitted light through the catheter wall. Commercially available catheters or those specially designed for passage of radiation may be used.Type: ApplicationFiled: April 1, 2009Publication date: October 15, 2009Inventor: Jeremy P. Segal
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Publication number: 20090257911Abstract: In one aspect, there is provided assembling an analyte sensor with an analyte sensor insertion device, packaging the assembled analyte sensor and sensor insertion device in a substantially airtight seal, and irradiating the packaged assembled analyte sensor and sensor insertion device at a predetermined dose using one or more electron beam accelerators.Type: ApplicationFiled: April 10, 2009Publication date: October 15, 2009Applicant: Abbott Diabetes Care Inc.Inventors: Christopher Allen Thomas, Jasmin Y. Zhao
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Patent number: 7601298Abstract: Apparatus (10), systems and methods are disclosed for treating a biological fluid with light. A container (206) of biological fluid is introduced into a fluid treatment chamber (40) where it is contacted with light provided by one or more light sources (60, 70) in proximity to the fluid treatment chamber (40). A light sensing system (650) senses the intensity of illumination of the light. A radiometer (460) may be inserted into fluid treatment chamber (40) to calibrate the light sensing system (650). An electronic control system (600) utilizes an interface circuit board (606) to interface a computer circuit board (602) to a display panel (37), a user interface panel (39, 39a), a relay circuit board (640), light sensors 404 and various other sensors (649). A detector (385) senses agitating movement of a tray (90) that contains biological fluids.Type: GrantFiled: May 31, 2006Date of Patent: October 13, 2009Assignee: Fenwal, Inc.Inventors: Jeffrey M. Waldo, Walter Page Hatch
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Publication number: 20090246073Abstract: An antimicrobial treatment method for non-thermal pasteurization and anti-microbial treatment of solid, semisolid, or liquid foods in industrial food transport systems is provided. For solid food applications, the method and related apparatus comprises a conveyor-based transport system. For semisolid or liquid food applications, the method and related apparatus comprises a conduit-based transport system. Both the conveyor-based and conduit-based transport systems are capable of treating food with ultrasound, a UV-ruby lightwave combination, a pulsed electric field, and/or a magnetic field. The method is capable of realizing greater than 3 log reductions in live microbes in foodstuffs, although the technology may be used in nonfood applications.Type: ApplicationFiled: March 26, 2008Publication date: October 1, 2009Inventor: Rong Yan Murphy
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Publication number: 20090242477Abstract: The present invention is characterized in that a base material comprises ester groups in the main chain and/or in the side chain(s), and comprises a polymer having hydrophobic groups. Particularly, the hydrophobic groups can be introduced by irradiating the base material with a radiation during the base material contacts an aqueous solution of a monohydric alcohol or an aqueous solution of an alcohol having not less than 2 hydroxyl groups, which is a monomer or a polymer, and which has one or more carbon atoms between the carbon atoms to each of which the hydroxyl group is bound in the monomer or in each monomer constituting the polymer.Type: ApplicationFiled: March 28, 2006Publication date: October 1, 2009Inventors: Miho Araki, Yoshiyuki Ueno, Hiroyuki Sugaya
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Patent number: 7595020Abstract: An improved singlet oxygen generator (SOG) and method of using gas phase electronically excited states of oxygen for bio-medical and chemical treatment applications are disclosed. According to the invention, both gas phase O2(1?) and O2(1?) are used for medical treatment, sterilization, and deactivation of biological and chemical agents, including diseased tissue and biological and chemical weapons. The improved SOG is compact and scalable, portable, capable of operating in a zero-gravity or low gravity environment, may use gaseous diluent or buffer gas, and is capable of operating at pressures as high as one atmosphere. The SOG is capable of operating within a short distance of the target site for the electronically excited states of oxygen, which are delivered to the target site via a conduit. The SOG and delivery system provide higher yields of electronically excited oxygen with longer lifetimes suitable for bio-medical applications.Type: GrantFiled: March 8, 2004Date of Patent: September 29, 2009Assignee: KSY CorporationInventor: George Emanuel
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Publication number: 20090232700Abstract: The present invention relates to methods of making a sterilized biosensor, where the biosensor comprises at least one binding reagent, which comprises at least one non-enzyme proteinaceous binding domain. Certain embodiments of the methods described herein comprise partially assembling the components of the biosensor, except for the binding reagent, and separately sterilizing this partial assemblage and the binding reagent. The sterilized binding reagent and the sterilized partial assemblage are then aseptically assembled to produce the sterilized biosensor. Other embodiments of the methods described herein comprise assembling substantially all of the components of the biosensor, including the binding reagent, and sterilizing the assembled biosensor to produce a sterilized biosensor.Type: ApplicationFiled: May 12, 2009Publication date: September 17, 2009Inventors: Javier Alarcon, Kristin Weidemaier, David M. Kurisko, Srinivasan Sridharan
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Patent number: 7588720Abstract: The present invention provides a method and apparatus for sterilizing articles using an ozone-containing gas, where condensation of water from the sterilization atmosphere during the sterilization process is substantially prevented. The inventive sterilization method includes providing a sterilization chamber and placing an article into the sterilization chamber. The sterilization chamber is sealed prior to equalizing the temperature of the article and the atmosphere in the sterilization chamber. A vacuum is applied to achieve a preselected vacuum pressure in the sterilization chamber. Once the vacuum pressure is set, water vapour is supplied to the sterilization chamber. Ozone-containing gas is then supplied to the sterilization chamber and the sterilization chamber remains sealed for a preselected treatment period, where the sterilization chamber remains sealed throughout the whole process. Finally, vacuum in the sterilization chamber is released.Type: GrantFiled: October 31, 2006Date of Patent: September 15, 2009Assignee: TSO3, Inc.Inventors: Richard Turcot, Simon Robitaille, Sylvie Dufresne
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Publication number: 20090214382Abstract: Methods are disclosed for sterilizing biological materials to reduce the level of one or more biological contaminants or pathogens therein, such as viruses, bacterial (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, and/or prions or similar agents responsible. These methods involve the use of alpha-keto acids in methods of sterilizing biological materials with irradiation.Type: ApplicationFiled: May 5, 2005Publication date: August 27, 2009Inventors: Wilson Burgess, David Mann, William Drohan, Shirley Miekka
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Patent number: 7579607Abstract: An installation for sterilizing articles comprises an enclosure having an inlet opening and an outlet opening, a support device for moving the articles inside the enclosure, and two electron bombardment members disposed on different orientations relative to the articles to be sterilized and inclined relative to the longitudinal axis of the articles.Type: GrantFiled: January 19, 2005Date of Patent: August 25, 2009Assignee: Serac GroupInventors: Guy Dumargue, Bertrand Gruson, Delphine Raynaud
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Publication number: 20090202387Abstract: An implantable system having internal circuitry configured to withstand a pre-determined amount of sterilization radiation is provided. In general, the system includes an internal control module in electrical communication with an implantable medical device. The internal control module can include a circuit board configured to withstand radiation and/or any number of integrated circuits (e.g., application specific integrated circuits) wherein the circuits or at least some portion thereof are fabricated so as to withstand some amount of radiation. For example, some portion of the circuitry can be fabricated utilizing radiation compliant material(s), silicon-on-insulator technology, and/or gallium arsenide technology. Additionally, the circuitry can include various components which are inherently resistant to such radiation (e.g., components fabricated utilizing magnetic field based technology, surface acoustical wave devices, etc.).Type: ApplicationFiled: February 8, 2008Publication date: August 13, 2009Applicant: ETHICON ENDO-SURGERY, INC.Inventors: Daniel F. Dlugos, JR., Mark S. Ortiz, David N. Plescia, Mark Leuenberger
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Patent number: 7569181Abstract: A method of deactivating chemical contaminants and biological agents from a target surface by and aerosol spraying the target surface with a electrostatically charged, photosensitizer solution, and then illuminating the surface with ultraviolet light.Type: GrantFiled: December 31, 2003Date of Patent: August 4, 2009Assignee: Clean Earth Technologies, LLCInventor: Jeffry Golden
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Publication number: 20090186332Abstract: A method for the preparation of antimicrobially active materials is presented. The invention involves taking a base material such as allografts, xenografts, polymers, metals, and ceramics and combining it with an antimicrobially active agent, such as antibiotics, antibacterials, antifungals, antivirals, disinfectants, and polypeptides, after which it is irradiated with ionizing radiation to sterilize and stabilize the combined material. The resulting antimicrobially active material may then be stored at ambient temperature while maintaining its antimicrobial activity and the structural integrity of the base material. The invention is particularly useful for both preventing and treating a variety of infections and for increased safety in reconstructive procedures.Type: ApplicationFiled: March 15, 2007Publication date: July 23, 2009Inventors: Ernest K. Manders, Christan D. Manders
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Patent number: 7553446Abstract: A decontamination method is provided that contacts a biologically contaminated object with first radiation having a first wavelength distribution and with second radiation having a second wavelength distribution. The first radiation kills at least most of the microbes on the surface of the contaminated object but not in an interior region of the object. The second radiation kills at least most of the microbes in the interior region of the object.Type: GrantFiled: April 28, 2005Date of Patent: June 30, 2009Assignee: Astralux, Inc.Inventors: Randolph Edward Treece, Jimmy Ray Smith, Jr., Douglas W. Swartz
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Publication number: 20090155490Abstract: The invention relates to a method for the plasma treatment of workpieces, particularly workpieces in the form of hollow bodies, in which a treatment zone in a reactor chamber is at least partially evacuated, a process gas is introduced into the treatment zone, particularly into the cavity of the workpiece, and a plasma is ignited by means of injected electromagnetic energy in the process gas introduced into the treatment zone, wherein the process gas flows through the treatment zone between opposite ends of the zone during the plasma treatment.Type: ApplicationFiled: August 24, 2006Publication date: June 18, 2009Applicant: SCHOTT AGInventors: Matthias Bicker, Robert Hormes, Manfred Lohmeyer
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Publication number: 20090155224Abstract: Water-soluble dimethyl amino ethyl ether psoralens useful in the treatment of proliferative skin disorders, microbial infections and diseases, disorders of the blood and bone marrow of mammals and in microbiocidal compositions for sterilization of blood and blood products and surgical implants and inhibition of microbial growth in industrial applications are provided.Type: ApplicationFiled: June 27, 2008Publication date: June 18, 2009Inventors: Jeffrey D. Laskin, Diane E. Heck, Ned D. Heindel
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Patent number: 7547413Abstract: Methods and systems for generating steam vapor having low zeta potential mineral crystals capable of disinfecting surfaces and objects upon an exposure period to the steam vapor. The steam vapor system comprises an aqueous liquid source having a threshold concentration of selected minerals, a liquid treatment system for treating the aqueous source liquid to produce treated liquid having an enhanced concentration of low zeta potential mineral crystals, and a steam vapor generator for producing steam vapor from the treated liquid, whereby the steam vapor has a higher concentration of low zeta potential mineral crystals than the aqueous liquid source. The steam vapor generated from the treated liquid is applied to surfaces or objects.Type: GrantFiled: February 7, 2006Date of Patent: June 16, 2009Assignee: Bauer Energy Design, Inc.Inventor: Walter J. Bauer
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Publication number: 20090148340Abstract: A method and an apparatus for sterilizing packaging material for use in packaging for protein containing products, such as food products or medical drugs. The packaging material is sterilized by irradiating it using a beam of ionizing radiation, such as an electron beam or a beam of gamma rays. Afterwards, the packaging material is processed in such a manner that protein reactive substances or compounds formed in the packaging material during the irradiation step are at least partly removed or rendered inreactive with respect to proteins. The processing step may advantageously be performed by heating the packaging material. Preferably, the processing step involves accelerating diffusion from the packaging material of protein reactive substances or compounds. Since the protein reactive substances or compounds are removed or rendered inreactive with respect to proteins, degradation of the product which is later stored in the packaging material is considerably reduced.Type: ApplicationFiled: February 28, 2007Publication date: June 11, 2009Applicant: Nova Nordisk A/SInventors: Lasse Hansen, Anders Dossing, Per Jeppesen, Signe Agnete Christensen
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Patent number: 7544323Abstract: A method for treating a fluid to increase oxygen content while reducing surface tension. The first step is flowing a fluid into a surface tension modification device at a first pressure and applying a frequency from about 0.05 Hz to about 5000 Hz into the fluid to modify a physical characteristic of the fluid forming an altered fluid. The next step is flowing oxygen or ozone into the altered fluid forming an altered fluid mixture. After the altered fluid mixture is formed, then flow the altered fluid mixture into the inner chamber of a multichamber device at a second pressure which is lower than the first pressure. The last step is passing the altered fluid mixture from the inner chamber through a plurality of funnels forming a turbid fluid condition at a focus point in an outside chamber to dissolve nano-sized oxygen particles into the fluid at an increased concentration.Type: GrantFiled: May 27, 2005Date of Patent: June 9, 2009Assignee: Innovative Industries, Inc.Inventors: James Richard Von Krosigk, Larry John Dove
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Publication number: 20090131876Abstract: A shieldable needle assembly is provided containing a shield with one or more reduced stress living hinges (10) which remain in the folded position. Methods of removing substantially all of the internal stress in the living hinge of a needle shield are also provided comprising irradiating and/or heat treating the living hinge.Type: ApplicationFiled: October 12, 2006Publication date: May 21, 2009Inventor: Martin M. Coyne
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Publication number: 20090129973Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The tube and barrier maintain stability of one or more analyte levels, including potassium and glucose, within 10% of their initial values before centrifugation for at least four days.Type: ApplicationFiled: November 14, 2008Publication date: May 21, 2009Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventor: Jane Emerson
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Patent number: 7534740Abstract: A method to produce photo-catalyst physical water molecule for medical purposes includes the following steps: mixing aqua pura and TiO2 at the ratio of 1:1 at a temperature range of 50 to 60° C. to be ground and refrigerated in flasks of a first semi-product; adding aqua pura at the ratio of 1:1 and mixing well to become a second semi-product; diluting with aqua pura and mixing well to indicate a viscosity of 800 to 10000 centipoises; storing the solution in a sealed and transparent container to undergo photosynthesis for 24 hours at a temperature range of 40 to 50° C.; ridding off 1% suspension and foreign matters and impurities of the sediments to avail solution of 20% solid containment; finally diluting with approximately 100% aqua pura to 0.3 to 0.8%.Type: GrantFiled: July 24, 2006Date of Patent: May 19, 2009Inventor: Tsai-Chuan Lu
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Patent number: 7520108Abstract: A method for sterilizing at least partly formed packages with electron beam irradiation in a packaging machine involves sterilizing each of at least two at least partially separate areas of the package by way of a respective electron beam sterilizing device, with each of the sterilizing devices being adapted to characteristics of each respective one of the two areas, and also performing a respective relative movement between the package and each of the electron beam sterilizing devices, which movements are adapted for the sterilization of each respective one of the two areas with the sterilizing devices.Type: GrantFiled: June 13, 2007Date of Patent: April 21, 2009Assignee: Tetra Laval Holdings & Finance SAInventors: Anders Kristiansson, Lars Åke Näslund, Anders Hedse Olsson
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Patent number: 7513193Abstract: The present invention is related to method for irradiating bulk material, particularly for treatment of food products such as grain, characterized in that in the case of a failure of said irradiation, the untreated bulk material is separated from the treated material and subsequently transported back towards the beginning of the process, in order to be treated. The invention allows to avoid re-treatment of large quantities of material, and provides a clear separation between contaminated and uncontaminated parts of the installation.Type: GrantFiled: August 20, 2002Date of Patent: April 7, 2009Assignee: Ion Beam Applications S.A.Inventors: Wickham Allen, Philippe Peltier, Noel Goethals
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Publication number: 20090081075Abstract: A highly versatile method of a sterilization and a sterilization apparatus, in which objects with poor heat resistance that are to be sterilized, such as plastic products, can be sterilized without incurring thermal damage, with such a strong sterilization power that spores can be killed. A treatment chamber is filled with a treatment gas containing HCHO, and any sterilization objects placed in the treatment chamber are sterilized. During sterilization, while maintaining the interior of the treatment chamber at a pre-determined temperature (T1), the treatment gas is fed into the treatment chamber, and the sterilization objects are exposed to the treatment gas for a pre-determined period of time (h1).Type: ApplicationFiled: August 10, 2005Publication date: March 26, 2009Inventors: Tomohiko Hashiba, Koji Kawamura
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Patent number: 7507369Abstract: The present invention relates generally to systems and methods of disinfecting and/or decontaminating articles, and more specifically to a system and method of efficiently disinfecting and/or decontaminating articles such as pieces of mail that may have been exposed to diverse biological and/or chemical contaminants.Type: GrantFiled: February 4, 2005Date of Patent: March 24, 2009Assignee: BioDefense CorporationInventor: Michael Yuan Lu
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Patent number: 7507370Abstract: Methods and systems for establishing Taylor-Couette flow in a fluid are provided. Aspects of the disclosed methods and systems incorporate Taylor-Couette flow in combination with a source of radiation to provide more uniform radiation exposure to the fluid and its components. Common problems of non-uniform radiation levels and concentration boundary layer effects in UV reactors are largely eliminated using the methods and devices provided herein. In an exemplary embodiment, the reactor of the present disclosure has a hollow outer cylinder or stator and a rotor positioned therein and smooth walls for both the outer wall of its rotor and the inner wall of the outer cylinder or stator in which the rotor is positioned, the space between which forming the annular fluid gap.Type: GrantFiled: February 21, 2006Date of Patent: March 24, 2009Assignee: Georgia Tech Research CorporationInventors: Larry Forney, John Pierson
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Publication number: 20090074610Abstract: It has been determined that gamma sterilization of biodegradable polymer stents does not cause significant polymer cross-linking and collapse. Using sufficient spacing can lead to stents that display little if any detrimental effects from the procedure. In certain embodiments, using structures in the general region of about 100 micron spacing between the struts leads to highly functional stents that do not fuse. Further, the resulting stent has radially homogenous mechanical properties. Therefore, the stent has a uniform expansion within the lumen.Type: ApplicationFiled: March 13, 2007Publication date: March 19, 2009Inventor: Patrick Sabaria
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Publication number: 20090060780Abstract: A device for the treatment and/or decontamination of surfaces has at least one generator configuration with which directed waves, in particular of an electromagnetic type, can be generated and its energy transmitted by a transmission device onto contaminated surface deposits, in particular surface deposits of a reactor pressure vessel and/or reactor internals. The surface deposits are dissolved and/or sublimated by the directed waves. In a corresponding method, the device is used to generate the directed waves and bring about transmissions of energy onto the contaminated surface deposits, in particular surface deposits of a reactor pressure vessel and/or reactor internals, in such a way that these surface deposits are dissolved and/or sublimated.Type: ApplicationFiled: September 2, 2008Publication date: March 5, 2009Applicant: Westinghouse Electric Germany GmbHInventors: Konstantin Walter, Johannes Scharrer
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Patent number: 7497990Abstract: A process for the destruction of microorganisms on a product using ultrasonic energy is disclosed. The process comprises contacting a product with an ultrasonic horn assembly and generating ultrasonic energy sufficient to result in a microorganism destruction rate of at least a 1-log kill.Type: GrantFiled: December 30, 2004Date of Patent: March 3, 2009Assignee: Kimberly-Clark Worldwide Inc.Inventors: Timothy James Blenke, Tom Ehlert, James Jay Tanner, David W. Koenig, Bernard Cohen
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Publication number: 20090041618Abstract: A porous metal filter for use in conjunction with a sterilization container where the porous metal filter is fabricated from metal powder or metal pellets having an average particle size of at least greater than 0.2 microns and a thickness of at least about 15 mils (0.015?, about 381 microns) is disclosed. The filter is compatible with all current sterilization environments and all current sterilization procedures.Type: ApplicationFiled: July 9, 2008Publication date: February 12, 2009Inventors: Marcia A. Frieze, Allan S. Frieze
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Publication number: 20090035178Abstract: A process for the destruction of microorganisms on a product using ultrasonic energy is disclosed. The process comprises contacting a product with an ultrasonic horn assembly and generating ultrasonic energy sufficient to result in a microorganism destruction rate of at least a 1-log kill.Type: ApplicationFiled: December 30, 2004Publication date: February 5, 2009Applicant: Kimberly-Clark Worldwide, Inc.Inventors: Timothy James Blenke, Tom Ehlert, James Jay Tanner, David W. Koenig, Bernard Cohen
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Patent number: 7485258Abstract: A method and device for sterilizing containers in which a plasma treatment is executed through excitation of an electromagnetic oscillation so that the plasma is excited in a vacuum in the vicinity of the container regions to be sterilized. Between arrival and discharge, the container regions to be sterilized are moved closer to the oscillation-generating device in the chamber, with continuous movement of the container and/or of the oscillation-generating device for one or more predetermined time intervals in such a way that a plasma is excited in these regions inside and/or outside the container. The chamber is provided with a transport apparatus inside it, which produces an essentially rotating motion of the container during the transport from the arrival to the discharge in the chamber.Type: GrantFiled: July 9, 2002Date of Patent: February 3, 2009Assignee: Robert Bosch GmbHInventors: Kurt Burger, Guenter Schneider, Thomas Beck, Wolfgang Szczerba, Bernd Wilke, Johannes Rauschnabel, Sascha Henke, Bernd Goetzelmann, Heinrich Van De Loecht, Wolfgang Schmitt
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Publication number: 20090028749Abstract: A process for reducing the microbial contamination of dampening agent cycles, comprising the step of electrochemically treating the dampening agent.Type: ApplicationFiled: April 25, 2006Publication date: January 29, 2009Inventor: Helmut Sander
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Patent number: 7481777Abstract: A lancet integrated test element tape includes a plurality of lancet integrated test elements. The lancet integrated test elements each include a lancet configured to form an incision in tissue and a test element configured to analyze body fluid from the incision in the tissue. A cartridge includes a supply compartment configured to store an unused section of the tape. The tape is folded within the supply compartment to limit damage to the lancet integrated test elements. The cartridge can further include a waste compartment in which a used section of the tape is stored. An indexing mechanism moves the tape between the supply and waste compartments.Type: GrantFiled: January 5, 2006Date of Patent: January 27, 2009Assignee: Roche Diagnostics Operations, Inc.Inventors: Frank A. Chan, Daniel Wong
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Publication number: 20090016930Abstract: A sanitizer utilizing electrical fields for hands and gloved hands. The sanitizer includes a power supply, a first and second electrode, and a dielectric between the first and second electrode. For sanitizing the outer surface of a glove, the first electrode is disposed inside the glove and the second electrode is disposed near the outer surface of the glove. A signal generator produces a high-voltage, periodic signal across the first and second electrode for a predetermined period of time to generate an electrical field configured to inactivate pathogens between the two electrodes. The second electrode can include a metallic layer or a conducting liquid in which a gloved hand is inserted. Alternatively, an electric field can be generated between the stratum corneum of a user's skin and an outer conducting layer of a glove so as to deactivate pathogens on the surface of the hand.Type: ApplicationFiled: July 14, 2008Publication date: January 15, 2009Applicant: Germgard Lighting, LLCInventor: Eugene I. Gordon
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Publication number: 20090013646Abstract: An apparatus for sterile filling of beverage containers has a first module and a second module. The first module rinses and sterilizes empty containers and delivers the sterilized containers to the second module. The second module fills and caps the containers with beverage product at ambient temperature in an active sterilization zone utilizing an e-beam sterilization unit.Type: ApplicationFiled: July 10, 2008Publication date: January 15, 2009Applicant: Stokely-Van Camp, Inc.Inventors: Michael J. Mastio, Rei-Young Amos Wu, Michael F. McGowan, Subodh K. Raniwala, Gregory Schimmel, James D. Schuman, Richard O. Powell
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Publication number: 20090010802Abstract: An integrated disposable includes a test strip and a lancet packet coupled to the test strip. The lancet packet includes a sterility sheet enclosing at least a portion of a lancet to maintain the sterility of the lancet. The lancet packet and the sterility sheet, in particular, allow the lancet to be sterilized separately from the test strip. The lancet in one form is incorporated into a lancet tape that is sterilized in a continuous, reel-to-reel sterilization process. The lancet tape in one form is sterilized using an electron beam sterilization process. With electron beam sterilization, sterilization is enhanced by irradiating both sides of the tape with electron beams. Sterilization can adversely affect chemical reagents in the test strip. To alleviate this chemistry degradation issue, the lancet packet is attached to the test strip after the lancet is sterilized.Type: ApplicationFiled: July 25, 2008Publication date: January 8, 2009Inventors: Abner David Joseph, Frank A. Chan, Steven N. Roe
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Publication number: 20090012466Abstract: A method for inhibiting adverse reaction of the contents of a prefilled container during a radiation sterilization procedure is disclosed. In the method, a container which is made of a material including a radiation stable polyolefin is prefilled with a medium prior to being subjected to a gamma irradiation sterilization treatment. By using a radiation stable polyolefin material as the container, such as a polyolefin with a radiation stabilizer additive, and by prefilling the container prior to the gamma irradiation treatment, the container can be effectively sterilized without adversely affecting its contents.Type: ApplicationFiled: September 15, 2008Publication date: January 8, 2009Applicant: BECTON, DICKINSON AND COMPANYInventors: Xia Zhao, Jane Ren, Robert Odell, Patti Paterson
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Publication number: 20090000040Abstract: Provided is a fabric structure treatment apparatus in which it is not required to heat at a high temperature a fabric structure and/or components of the treatment apparatus, which are/is targeted for sterilization; in which a dry state is not necessarily required; which does not bring about deterioration, discoloring, and the like of the fabric structure and/or components of the treatment apparatus, targeted for the sterilization; the fabric structure and/or components of the treatment apparatus, targeted for the sterilization, are not damaged; and which is capable of attaining sufficient bactericidal action.Type: ApplicationFiled: December 20, 2006Publication date: January 1, 2009Inventor: Mugihei Ikemizu
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Publication number: 20090004049Abstract: Disclosed is an irradiation method which includes addition of vitamin C during sterilization of bone restorative demineralized bone matrix (DBM) with irradiation, so as to inhibit reduction of physical properties of a carrier containing DBM caused by irradiation and protect DBM formable bone morphogenetic protein (BMP) from irradiation. The method according to the present invention can provide bone restorative materials with more excellent stability and effectively controlled modification of physical properties by employing a sterilization process accompanied with addition of vitamin C during irradiation.Type: ApplicationFiled: August 17, 2007Publication date: January 1, 2009Inventors: Myung-Woo Byun, Ju-Woon Lee, Jong-Il Choi, Jae-Hun Kim, Beom-Seok Song
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Publication number: 20090000639Abstract: Method and system are disclosed for coupling energy from at least on energy source, e.g. UV light source, ultrasonic transducer, or combination thereof, to a target site, e.g. hazardous bacteria, through a streaming liquid, e.g. water. The bacteria toward which energy is to be coupled could be present in the water stream itself and/or on a surface toward which the water stream is to be launched at the end of its flow. Accordingly, in-line aseptic filling is provided, which can fill and simultaneously disinfect a container. According to another embodiment where the water is used for washing, in-line aseptic washing device is provided. A variety of other embodiments is disclosed as well.Type: ApplicationFiled: August 4, 2004Publication date: January 1, 2009Inventors: Zamir Tribelsky, Joseph Rabani, Mordechai Navon, Gil Cohen
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Publication number: 20080319380Abstract: The present invention overcomes the difficulties in the sterilization and delivery of viscous, multi-component compositions that require pre-mixing prior to usage by disclosing a sterile, multi-component, ready-to-use product wherein each component is sterilized independently and then assembled into a sterilized delivery kit. In certain preferred embodiments of the present invention, a sterile, polymerizable system is provided that comprises a plurality of sterile polymerizable monomers, said monomers having been sterilized by passing them through a filter; at least one sterile filler which has been exposed to conditions effective to render said filler sterile, and the sterile monomers and the sterile filler being blended together to form at least one substantially homogeneous blend contained within a sterile delivery vessel.Type: ApplicationFiled: September 5, 2008Publication date: December 25, 2008Applicant: Vita Special Purpose CorporationInventors: Vasanth Prabhu, Jeffrey J. Wicklund, Erik M. Erbe, Anthony M. Wilkes
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Publication number: 20080319137Abstract: An antioxidant combined with UHMWPE prior to subjecting the UHMWPE to crosslinking irradiation. In one exemplary embodiment, the antioxidant is tocopherol. After the antioxidant is combined with the UHMWPE, the resulting blend may be formed into slabs, bar stock, and/or incorporated into a substrate, such as a metal, for example. The resulting product may then be subjected to crosslinking irradiation. In one exemplary embodiment, the UHMWPE blend is preheated prior to subjecting the same to crosslinking irradiation. Once irradiated, the UHMWPE blended product may be machined, packaged, and sterilized in accordance with conventional techniques.Type: ApplicationFiled: April 10, 2008Publication date: December 25, 2008Applicant: ZIMMER, INC.Inventors: Alicia Rufner, John Knight, Toni Rowe, Dirk Pletcher, Ray Gsell, Hallie E. Brinkerhuff, Werner Schneider