Abstract: Different aspects of the invention refer to a disinfection apparatus, and corresponding method, for wood barrel disinfection using microwave shock pulse, MwSP, technology for the complete elimination of microbial populations. This is accomplished by a system which ensures deep and complete disinfection, however such that the temperature is maintained below material degradation level. Complete disinfection is achieved due to effectiveness up to the deepest layers. The wooden barrel material is however preserved, due to the non-harmful nature of the dosage regime programmed into the radio frequency emission.

Abstract: Embodiments disclosed include autonomous robotic systems and methods for disinfecting an environment. An autonomous disinfecting system comprises, in a housing, a first unit comprising a first plurality of UV-C lamps attached to a first wireless base comprising a plurality of wheels. Preferably, the first unit further comprises a docking port for a second unit comprising a second plurality of UV-C lamps attached to a second wireless base, and a motion sensor configured to send a signal to a processing unit comprised in the autonomous disinfecting system wherein the processing unit is configured to shut down the system when it receives a signal indicating a detected movement.

Abstract: An automatic washer for continuous positive airway pressure equipment has a housing defining a wash chamber having an open face providing access to the wash chamber, a door selectively closing the open face, a dual eccentric nozzle protruding into the wash chamber, a rack slidingly receivable within the wash chamber, and a spray nozzle in the bottom surface of the wash chamber. The rack has a hose clamp oriented to secure an end of a CPAP hose when seated in the rack with an open end of the CPAP hose facing the dual eccentric nozzle. The dual eccentric nozzle has an air conduit that introduces air during a drying cycle and a water conduit that introduces water during a rinse cycle, and when the rack is fully inserted in the wash chamber, the dual eccentric nozzle is received inside the hose clamp, thereby, inside the CPAP hose when present.

Abstract: Device and method suitable for disinfecting herbs using plasma are disclosed. The device comprises a chamber and two sets of electrodes in an opposed position one relative to the other, inside the chamber. Each electrode in one set has a counterpart electrode in the other set, the two electrodes positioned facing each other and being configured to connect to a RF HV power supply, to produce a plasma-generating EM field in the space between the electrodes. The device further comprises a dielectric carrier positioned inside the chamber in the space between the two sets of electrodes, the carrier being dimensioned and configured to carry herbs in granular form such as powder or particles thereon. A portable sealable container comprising a unidirectional valve is also disclosed, configured to store herbs thereinside during plasma treatment in the device, and to store the disinfected herbs after treatment under vacuum.

Abstract: In one aspect of the invention, a dye sensitized solar cell has a counter-electrode including carbon-titania nanocomposite thin films made by forming a carbon-based ink; forming a titania (TiO2) solution; blade-coating a mechanical mixture of the carbon-based ink and the titania solution onto a substrate; and annealing the blade-coated substrate at a first temperature for a first period of time to obtain the carbon-based titania nanocomposite thin films. In certain embodiments, the carbon-based titania nanocomposite thin films may include solvent-exfoliated graphene titania (SEG-TiO2) nanocomposite thin films, or single walled carbon nanotube titania (SWCNT-TiO2) nanocomposite thin films.

Abstract: Provided are a system and method for sterilizing one or more medium via plasma exposure. The sterilization may be accomplished by exposing a respective medium to a given electrical field generated by electrodes disposed to target such medium, and through, optionally, further application of a magnetic field having a portion thereof disposed orthogonally to the generated electrical field.

Abstract: A method and apparatus for decontaminating substantially enclosed environments by using ultrasonic cavitation of a cleaning fluid to produce a low pressure, low air flow mist that can be activated by a nonthermal plasma actuator to create a cloud of activated hydroxyl species with the capacity to decontaminate articles, open surfaces or substantially enclosed spaces of pathogens, including bacteria, and other pathogenic microorganisms. An automated system and related non-transitory computer medium are also disclosed.

Abstract: A system and apparatus for sanitizing person use items. The system is comprised essentially of a mechanism for emitting sanitizing electromagnetic radiation within an enclosed compartment. The apparatus may be light-tight such that the radiation is contained within the apparatus. It may be configured to emit a plurality of sanitizing wavelengths. The apparatus may include a series of reflective and/or refractive apparatuses to alter the reflection path of the emitted electromagnetic radiation, allowing the electromagnetic radiation to reflect in a plurality of directions. The enclosure may include a support member or personal item support that may be transparent to, or reflective of, the electromagnetic radiation.

Abstract: An apparatus and to a method for treating layers using a plasma zone sealed from the outer atmospheric pressure are provided. The apparatus and method include a plasma reactor including a substrate carrier in form of a container receiving means, and a closing element that is joined with the substrate carrier by means of a lifting device.

Abstract: Summarizing the invention, a sensing element for monitoring the state of a single-use sterilizable element such as a single-use bioreactor, wherein the state of the single-use sterilizable element is determined by at least one environmental condition is provided. The sensing element comprises: a variable component having at least one physical property that is configured to change in response to the at least one environmental condition and/or a change thereof, wherein the variable component comprises a sensing material with changing absorption characteristics for electromagnetic radiation configured to change in response to the at least one environmental condition and/or a change thereof.

Abstract: An apparatus and to a method for treating layers using a plasma zone sealed from the outer atmospheric pressure are provided. The apparatus and method include a plasma reactor including a substrate carrier in form of a container receiving means, and a closing element that is joined with the substrate carrier by means of a lifting device.

Abstract: A method of sterilizing an article such as a flexible endoscope is performed in a sterilization chamber. A vacuum is applied in the sterilization chamber while the article is contained in the sterilization chamber. A sterilant is then introduced into the sterilization chamber. The pressure within the sterilization chamber is incrementally increased to provide a step-wise transition from a high vacuum state to atmospheric pressure. The article is thereby sterilized.

Abstract: A carbonation system for a beverage appliance or machine that can include a liquid chamber and a carbonation chamber separated from the liquid chamber by a wall of the carbonation chamber is disclosed herein. In some implementations, the liquid chamber is defined by a liquid tank (e.g., a water tank), and the carbonation chamber is defined by a carbonation tank. The carbonation system can move liquid (e.g., water) from the liquid chamber to the carbonation chamber and introduce carbonating gas (e.g., carbon dioxide) into the carbonation chamber to create a carbonated liquid (e.g., a carbon dioxide water dissolution, such as carbonated water, sparkling water, or seltzer).

Abstract: A station for a handheld information device (HID) includes a station body having a periphery and a receiving surface to support at least a portion of the HID. A visible antimicrobial illumination (VAI) emitter is coupled to the station body and arranged to direct a human-visible illumination beam at a target surface of the HID to produce an antimicrobial effect on the target surface. At least a first portion of the target surface is external to the periphery of the station body, and the human-visible illumination beam is projected beyond the periphery to illuminate the first portion of the target surface.

Abstract: A method for sterilizing an antiseptic solution includes providing a container containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85° C. to about 135° C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and has a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%.

Abstract: A cabinet provides a continuous sanitizing environment for items contained within the cabinet. The sanitizing environment is achieved by generated oxygen, ozone, and ultraviolet light within the cabinet. Expelled oxygen and ozone from the cabinet sanitize the ambient environment in which cabinet resides in.

Abstract: Methods and apparatus for evaluating the quality of an environment or process by measuring light emitted from a bioluminescent sample containing ATP, ADP, or alkaline phosphatase. The apparatus comprises a sample collection and analysis system used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The system includes an instrument having a photon detection assembly for use with the sample testing device and one or more probe assemblies that optically cooperate with the instrument. The instrument includes a dark chamber with a reflective interior surface which may be concave or preferably spherical, and a photon detection sensor such as a multi-pixel photon counter sensor. A substantially transparent portion of the probe assembly, and liquid contained therein, focus bioluminescence toward the photon detection sensor.

Abstract: The invention relates to a vacuum exhaust system of a sterilizer, comprising: a sterilization chamber; a first vacuum pump connected to one side of the sterilization chamber; an oil mist trap section for exhausting steam incoming from the sterilization chamber via the first vacuum pump; and a second vacuum pump connected to the first vacuum pump and the oil mist trap section. The vacuum exhaust system of a sterilizer according to the invention comprises the second vacuum pump connected to the first vacuum pump and the oil mist trap section, wherein by turning the second vacuum pump on to apply a vacuum to the operating oil in the first vacuum pump, thereby providing a certain pressure for evaporating water in liquid state to the first vacuum pump, the invention can vaporize the water vapor trapped in the operating oil in the first vacuum pump.

Abstract: A method of sterilizing an object with atomic nitrogen from a nitrogen plasma comprises the steps of positioning the object in a sterilization chamber, and conditioning the object present in the chamber. The step of conditioning includes a first stage of injecting atomic nitrogen into the chamber, during which a first concentration of atomic nitrogen in the chamber is imposed, a suction stage performed after the first injection stage, during which the chamber is evacuated, and a second stage of injecting atomic nitrogen into the chamber that is performed after the suction stage, during which a second concentration of atomic nitrogen is imposed in the chamber. The method further comprises a sterilization step of sterilizing the object, performed after the conditioning, and includes injecting atomic nitrogen into the chamber, during which step a concentration of atomic nitrogen in the chamber is imposed that is greater than the first and second concentrations.

Abstract: The present invention relates to a vacuum exhaust system of a sterilizer, comprising: a sterilization chamber; a first vacuum pump connected to one side of the sterilization chamber; an oil mist trap section for exhausting steam incoming from the sterilization chamber via the first vacuum pump; and a second vacuum pump connected to the first vacuum pump and the oil mist trap section. The vacuum exhaust system of a sterilizer according to the present invention comprises the second vacuum pump connected to the first vacuum pump and the oil mist trap section, wherein by turning the second vacuum pump on to apply a vacuum to the operating oil in the first vacuum pump, thereby providing a certain pressure for evaporating water in liquid state to the first vacuum pump, the present invention can vaporize the water vapor trapped in the operating oil in the first vacuum pump.

Abstract: Methods of combined sterilization and integrity testing of dialyzers such as hollow fiber dialyzers are disclosed. Sterilization and integrity testing may be performed by treating the dialyzer with a sterilization fluid for sterilizing at least the blood-side compartment of the dialyzer and for wetting the dialysis membrane of the dialyzer with the sterilization fluid, and carrying out an integrity testing of the dialysis membrane wetted with the sterilization fluid, wherein the sterilization fluid is selected from aqueous solutions containing peroxide and/or ozone, the peroxide being selected from peroxides which disintegrate into water, oxygen and/or volatile organic compounds, and from aqueous solutions containing chlorine, bromine and/or iodine.

Abstract: According to the present invention, a sterilant can be injected into a container without residual water on an object to be sterilized. The method includes decreasing a pressure in the container to a pressure higher than the triple point pressure at which water freezes. The method further includes comparing an actual time required for decreasing the pressure and a reference time, or comparing an actual rate of pressure increase and a reference rate to detect residual water on the object. If the residual water is detected, the pressure in the container is increased to the atmospheric pressure or the quasi-atmospheric pressure and the object is heated, and then the pressure is decreased to drain the residual water through the decompression boiling. The step of draining the residual water is repeatedly performed until no residual water is detected on the object and subsequently the sterilant is injected into the container.

Abstract: The invention relates to a device for sterilization of the interior surface of packaging containers with electron beam, comprising an emitter provided with an electron exit window. The emitter is adapted to emit charge carriers, such as electrons, through the electron exit window, said electrons forming an electron cloud. The device comprises at least one outlet adapted to provide a flow of sterile gaseous medium adapted to maintain a local aseptic zone around at least an emitter portion including the electron exit window, thus preventing any flow of medium from outside the local aseptic zone from coming into the local aseptic zone. The invention also relates to a method.

Abstract: The present invention provides a process for incorporating a wireless device into a plastic container as part of the steps of manufacturing the container. The plastic container can be a flexible plastic bag and are formed of one or more sheets, generally two or more sheets of plastic film or a rigid plastic container such as a tub or tote. The bags are formed by sealing together adjacent edge portions of each film layer. One embodiment of the present invention is to incorporate a wireless device between the edge portions of the film(s) before or during sealing so that the wireless device becomes permanently sealed into the film material but is isolated from both the bag interior and the outside environment. Another embodiment is to incorporate the wireless device onto or into a plastic component that is sealed to the container, such as a nipple or port, so that the wireless device becomes permanently sealed to the container but is isolated from both the container interior and the outside environment.

Abstract: The invention relates to a device for sterilization of the interior surface of packaging containers with electron beam, comprising an emitter provided with an electron exit window. The emitter is adapted to emit charge carriers, such as electrons, through the electron exit window, said electrons forming an electron cloud. The device comprises at least one outlet for conditioning at least a sterilized volume in the packaging container. The outlet is adapted to provide a flow of a sterile gaseous medium, thereby generating a first condition at least inside the sterilized volume of the packaging container. The first condition is adapted to prevent any flow of medium from outside the sterilized volume from coming into the sterilized volume without first being sterilized by the electron cloud. The invention also relates to a method.

Abstract: A method for removing biofilm from a lumen of a medical implant is disclosed. The method includes the steps of inserting a plasma applicator into a lumen defined in a medical implant, the lumen having a proximal end portion and a distal end portion having an opening therein, positioning the plasma applicator adjacent a biofilm formation, generating a selectively reactive plasma effluent at the plasma applicator and directing the selectively reactive plasma effluent at the biofilm formation.

Abstract: In a low temperature hydrogen peroxide gas plasma sterilizer, plasma within the sterilization chamber contributes to the sterilization process and decomposes the sterilant used at the end of a sterilization programs. The plasma however the must be properly profiled otherwise undesired surface etching may occur on the sensitive medical apparatus. This application describes a novel plasma control method and apparatus which minimize the harmful side effects plasma on the medical apparatus during a sterilization program.

Abstract: Extracorporeal systems and methods for treating blood-borne diseases in a subject or for developing drugs to treat blood-borne diseases include various environmental and treatment modules that can be tailored to a specific disease or infection. In certain embodiments of the systems and methods, a blood sample is treated with cold plasma and optionally with hydrostatic pressure, a pulsed electrical field, a pharmaceutical agent, microwave, centrifugation, sonification, radiation, or a combination thereof, under environmental conditions that are effective for the treatment.

Abstract: A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both.

Abstract: Low energy electron sterilizers and method of sterilization using low energy electrons are disclosed herein. An example method of sterilizing an instrument using low energy electrons can include generating one or more low energy electrons, maintaining the instrument in a vacuum and irradiating the instrument with the low energy electrons. The low energy electrons can have an energy less than or equal to 25 keV, and the vacuum can be sufficiently low to prevent the one or more electrons from producing a plasma.

Abstract: The invention relates in various embodiments to a composite useful as e.g. a medical implant device, and a method of treating fouling, including biofouling as may occur on an implant. The composite comprises a matrix phase and a patterned phase that comprises an energetically activatable wire intermixed with the matrix phase, the wire when energetically activated, which includes thermal activation, causes modification of at least a portion of the matrix phase to treat fouling that might otherwise occur. The method of treating biofouling may be practiced on a patent while the medical implant of the invention is in situ.

Abstract: A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both.

Abstract: Photothermal antibacterial material RMG is provided in the present invention, where R represents aldehyde, di-aldehyde or multi-aldehyde, M is magnetic material, and G is reduced graphene oxide. A method of synthesizing the abovementioned antibacterial material comprises of three steps. At first graphene oxide was synthesized, followed by simultaneous reduction and functionlization with MNPs and eventually an aldehyde is modified on magnetic material to yield magnetic G functionalized glutaraldehyde (RMG). We utilize the photothermal feature of graphene for antibacterial activity, in addition graphene was functionalized with aldehyde for capturing bacteria and with magnetic material to enhance a focusing of light irradiation. Moreover, the magnetic properties of material could help for reusability of antibacterial material.

Abstract: A stabilized mixed oxidant solution may be produced by flowing a starting solution (e.g., salt brine, hypochlorous acid, and/or sodium hypochlorite) through a flow-through electrochemical module including first and second passages separated by an ion permeable membrane while electric power is applied between an anode and cathode in electrical communication with the first and second passages, respectively. An initially acidic anolyte solution received from the first (anode) passage is stabilized by elevating pH to yield a stabilized mixed oxidant solution. Methods of using the mixed oxidant solution are further provided.

Abstract: A method and device are provided for treating flammable materials, fuels for example, by irradiation of the materials with ultra-violet radiation. In one embodiment, the apparatus suited for connection to a fuel line includes a body with centrally-formed duct and UV light sources mounted outside of the duct at upper and lower sides. It is to be appreciated that the invention has utility for many different fuel system applications, for example in aircraft, boats and in other motive vehicles. Further, the device can be conveniently mounted, if desired, on different fuel platforms including on bowsers.

Abstract: UV hard-surface disinfection system that is able to disinfect the hard surfaces in a room, while minimizing missed areas due to shadows by providing multiple UV light towers that can be placed in several areas of a room such that shadowed areas are eliminated and that can be transported by a cart that is low to the ground such that the towers may be loaded and unloaded easily by a single operator. The system is able to be controlled remotely, such that during activation of the system, no operator is present, and to automatically cut power to all towers in the event that a person enters the room.

Abstract: An object of the present invention is to efficiently sterilize microorganisms present in or on a surface of a liquid. Plasma is generated in a vicinity of or in a manner to make contact with a liquid whose pH value is adjusted to become 4.8 or lower, more preferably 4.5 or lower. The plasma is generated in an atmospheric gas containing nitrogen, e.g., in the air. Superoxide anion radicals (O2?.) that are generated by the plasma react with protons (H+) in the liquid to form hydroperoxy radicals (HOO.). Further, nitrogen and oxygen included in the air are combined together by the action of plasma to form nitrogen oxide such as nitric oxide (NO.). The nitric oxide (NO.) combines with the hydroperoxy radicals (HOO.) to become peroxynitrite (ONOOH(ONOO?)) having a high microbiocidal activity.

Abstract: Described herein are methods and compositions for killing or preventing the growth of microbes. It has been discovered that a class of porphyrins can kill or prevent the growth of microbes. The porphyrins can be used in a number of different applications where microbes grow.

Abstract: There is disclosed a composition for converting electromagnetic energy to ultraviolet C (UVC) radiation or radiation of a shorter wavelength, the composition comprising at least one phosphor capable of converting an initial electromagnetic energy (A) to an electromagnetic energy (B) comprising UVC radiation or radiation of a shorter wavelength, and an organic or inorganic media containing said phosphor. There is also a method of sterilizing an article by exposing it to UVC radiation or radiation of a shorter wavelength for a time sufficient to deactivate or kill at least one microorganism and/or for a time sufficient to inhibit abnormal cell growth within the body, when said composition is in an implantable medical device. A method of coating an article with such compositions is also disclosed.

Abstract: There is disclosed various devices and articles comprising phosphors for converting electromagnetic energy to radiation having a shorter wavelength, the composition comprising at least one phosphor capable of converting an initial electromagnetic radiation having a wavelength (A) to an electromagnetic radiation having a shorter wavelength (B) comprising UV radiation or radiation of a shorter wavelength. There is also a method of sterilizing such devices and articles by exposing it to UV radiation or radiation of a shorter wavelength for a time sufficient to deactivate or kill at least one microorganism and/or for a time sufficient to inhibit abnormal cell growth within the body, when the composition is in an implantable medical device.

Abstract: An apparatus, system and method for reducing the growth of microbial contamination, such as bacteria, virus, mold and biofilms, in an air-handling unit. The apparatus includes a mounting member configured to couple with a housing of an air-handling unit and a turbine coupled with the mounting member and configured to produce energy when positioned in an air flow path through the air-handling unit. The apparatus also includes an electrode assembly including an anode configured to be placed in a condensate pan and receive energy from the turbine. The anode produces agents that reduce the growth of microbial contamination when energized.

Abstract: An installation for treating articles with radiation, the installation comprising a structure having pivotally mounted thereon an inlet starwheel and an outlet starwheel respectively arranged facing an inlet and an outlet of a shielded enclosure in which there are mounted at least one pivotal treatment starwheel and at least one electron emitter in the vicinity of the treatment starwheel. The installation comprises a linear inlet conveyor and a linear outlet conveyor extending inside the shielded enclosure respectively facing the inlet and the outlet, the linear conveyors each comprising a respective transporter surrounding a shielded wall forming a baffle.

Abstract: Systems and methods for treating a fluid by passing fluid through a treatment structure, the fluid containing undesirable living things, the treatment structure containing electrically conductive nanomaterial with silver, flowing an electric current in the fluid in the treatment structure via the electrically conductive nanomaterial with silver or silver material to kill undesirable living things in the treatment structure, and killing undesirable things in the treatment structure.

Abstract: Disclosed is a method of controlling a real-time oxidation-reduction potential in a hot water system to inhibit corrosion in the hot water system. The method includes defining one or more operational protective zones in the hot water system. One or more of the operational protective zones includes an oxidation-reduction potential probe that is operable to measure a real-time oxidation-reduction potential in the hot water system at operating temperature and pressure. The probe transmits the measured real-time potential to the controller, which assesses and interprets the transmitted potential to determine whether it conforms to an oxidation-reduction potential setting. If the measured potential does not conform the oxidation-reduction potential setting, the controller is operable to feed or remove one or more active chemical species into or from the hot water system and further operable to change at least one system parameter.

Abstract: Process for treatment of residual nucleic acids present on the surface of laboratory consumables. The process combines two treatment phases: (1) treatment with ethylene oxide in gaseous phase; then (2) treating the surface with hydrogen peroxide in liquid phase or in gaseous phase. The effect of this treatment is the avoidance of the amplification of residual nucleic acids, in particular during PCR or TMA reactions.

Abstract: Methods and systems for surveying and sterilizing one or more areas or one or more portions of one or more areas are described.

Abstract: Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.

Abstract: Provided herein is methods of fabricating a medical implant and methods of using the same.

Abstract: To identify an alternative swelling medium with a hydrophilic polymer, we have observed that a swelling medium containing only 6% PEG 2000 and 0.9% NaCl failed to protect a hydrophilic coating during electron beam sterilization and subsequent storage at ambient and higher temperatures in an accelerated storage stability test. An unacceptably low dry-out time, below the specified 5 minutes, was obtained. However, when the biological buffer sodium citrate was added to a swelling medium containing PEG 2000, the performance of the stored catheters was as good as or better than the performance of catheters stored with the conventional swelling medium.

Abstract: A plasma sterilizing device has a container for a long tubule to be sterilized, having an adjustable internal pressure, and an electrode provided at at least one end of the long tubule. The device is configured so that plasma is generated inside the long tubule by applying an alternating current voltage to the electrode in such a state that the pressure inside and outside of the long tubule can be adjusted, so that there is a predetermined difference in pressure between the inside and the outside of the long tubule.