Abstract: An analytical system for performing centrifugal analysis on a working fluid with different components includes a uniform-dividing unit with a reduced cross section to divide the working fluid, a separating unit connected to the uniform-dividing unit, and a detecting unit. The detecting unit includes a detection compartment and a constant-quantity region connected to the separating unit through a separation channel. When rotating the uniform-dividing unit, the working fluid located at the uniform-dividing unit is transmitted to and separated by the separating unit, thereby causing one component of the working fluid to be separated from the other component and transmitted to the detection compartment through the constant-quantity region. With constant-quantity region, the detection compartment can be prevented from flushing by the excess of the separated component, and thus yield of product detection can be increased and different assays detection is carried out with a small sample volume at the same time.

Abstract: The present invention relates to a swing-out unit for a centrifuge, with the swing-out unit comprising sample vessel recesses and being insertable in a centrifuge rotor head to be swivelable about a swing-out axis, with the axes of at least two sample vessel recesses being arranged in a skewed manner with respect to one another. As a result, more sample vessels can be inserted in a swing-out unit than was previously possible with limited overall space.

Abstract: A bucket is provided for use with a centrifuge rotor. The bucket includes a bucket body that has a side wall and a bottom wall. A pair of projections extend from the side wall on opposing sides of the bucket body and are configured for engagement with the centrifuge rotor. The bucket also includes reinforcing material coupled to the projections for restricting movement of the bucket body relative to the projections during centrifugation on the centrifuge rotor. The projections may include bushings that extend outwardly from the side wall for engaging corresponding pins on the centrifuge rotor. The projection may alternatively or additionally include pins for engaging corresponding journals on the centrifuge rotor. The bucket body may include a pair of diametrically opposed apertures, with each of the projections extending through one of the apertures.

Abstract: A syringe for fat tissue components distinction including a specific gravity distinction member, and a fat tissue components separating method using the syringe. The syringe for distinguishing crude fat tissue components extracted from the human body into several fat tissue layers by specific gravity includes: a syringe main body in a cylindrical shape for storing the crude fat tissue components extracted from the human body, the syringe main body having a fat intake hole at a front end and an opening at a rear end; and a specific gravity distinction member disposed in the syringe main body and having a specific gravity smaller than about 1.0, wherein the specific gravity distinction member is movable into one of the fat tissue layers that has the same specific gravity as that of the specific gravity distinction member, thereby enabling fat tissue components distinction by specific gravity.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: A transportation system for transporting a biological material container between a sterile field and a nonsterile field and substantially maintaining sterility of the biological material container includes a housing assembly that removably houses the biological material container. The system also includes a port defined by the housing assembly, and the port provides communication into the biological material container from outside the housing assembly. The housing assembly includes a first member that covers a first portion of the biological material container such that a second portion of the biological material container extends from the first member. The housing assembly also includes a second member that covers the second portion of the biological material container. The second member is removably coupled to the first member to expose the second portion of the biological material container. A keying member that keys the transportation system in a centrifuge is also disclosed.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: The present invention relates to spin baskets or columns used in the preparation and purification of small sample volumes. The spin baskets of the invention are particularly designed to be used with microtubes and are adapted to connect with such microtubes.

Abstract: The centrifugation vessel includes an outer wall containing an interior space. A dam defines a barrier which divides the interior space into at least two regions including a catch basin defining a higher gee region and a reservoir defining a lower gee region. These regions are joined together over the dam. The dam includes a face which is preferably tapered to enable optimization of speed of separation of a sample placed within the vessel. The vessel is usable in a biological sample processing method by having the higher gee region of the vessel configured to have an elongate form and the volume optimized for collection of a higher density fraction of the sample. Supply and withdrawal tubes extend into the regions for reliable extraction and separate collection of differing density fractions after separation by centrifugation.

Abstract: A tube and float system for use in separation and axial expansion of the buffy coat includes a transparent or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The float includes a main body portion of reduced diameter to provide a clearance gap between the inner wall of the sample tube and the float. One or more protrusions on the main body portion serve to support the flexible tube. During centrifugation, the centrifugal force causes the diameter of the flexible tube to expand and permit density-based axial movement of the float in the tube. The float further includes a pressure relief system to alleviate pressure build up in the trapped red blood cell blood fraction below the float, thereby preventing red blood cells from being forced into the annular gap containing the buffy coat layers.

Abstract: An adapter for taking up a sample container and for use in a laboratory centrifuge rotor, the adapter including a closed end, an opened end and closure assembly that releasably seals the opened end. The closed end and the opened end can be of a certain diameter. The adapter can also be a certain shape. The closure assembly can also include a handle, flange, a hold down ring, a sealing ring and bottom support for the sealing ring, hold down ring, flange and handle.

Abstract: A centrifuge sample container includes: a body portion configured to contain a sample; and a cap portion configured to be engaged with and attached on the body portion. The body portion has a substantially triangular external shape defining three apex portions and three side portions between two of the apex portions when viewed from above and has a circular opening portion in an upper portion of the body portion. Distances between centers of the apex portions are equal to one another. Each of the apex portions is formed with a first radius of curvature when viewed from above. Each of the side portions is formed into a outwardly curved arc-like shape with a second radius of curvature when viewed from above.

Abstract: A g-force-sensitive label for detecting and indicating the application of a g-force is provided, the g-force sensitive label comprising an area for detecting and indicating an application of a g-force above a threshold value on the g-force sensitive label and an attachment area for attaching the g-force sensitive label on an object. At least one physical property of the area measurably changes its state upon applying a g-force above the threshold value, thereby altering a displayed pattern such that a machine-readable 1D or 2D or alphanumeric code is displayed.

Abstract: An anticoagulant-coated dipstick is selectively receivable by the central fill port of a rotor of a blood centrifuge. The dipstick includes an elongated, rod-like member having a first axial end and an opposite second axial end, and a cap affixed to the second axial end. At least a portion of a surface of the rod-like member is coated with an anticoagulant. The elongated rod-like member of the dipstick is dimensioned in length and diameter to be receivable through the central fill port of the rotor to contact a blood sample contained therein. The cap is circular in shape, with a diameter that is greater than that of the rotor fill port to entirely cover and seal the fill port to prevent leakage therethrough of a blood sample contained in the rotor, especially when the rotor is gently agitated or inverted.

Abstract: A fluid analytical device is provided including a body, a reservoir, an inlet channel and a separation unit. The reservoir is formed on the body. The inlet channel is formed on the body connected to the reservoir. The separation unit is formed on the body connected to the inlet channel, which includes a pile area, a collecting area and a spacer. The collecting area is located between the pile area and the reservoir. The spacer is formed between the pile area and the collecting area.

Abstract: Disclosed herein is a centrifugal rotor for delivering and analyzing biological sample. Chambers within the centrifugal rotor is used to split a biological sample, which comprises biological cellular components and biological fluids, into separate parts under centrifugal force after the biological sample being diluted, metered and distributed by the centrifugal rotor.

Abstract: A spinnable rotor for a high speed centrifuge includes a housing which defines a chamber interiorly thereof for receiving a whole blood sample and for containing a predetermined amount of red blood cell absorbent gel. The housing includes an upper portion and a bottom portion, the upper portion having a port formed through the thickness thereof. The upper portion has at least a portion thereof formed from a light transmissible material. A light pipe is joined to the upper portion and light transmissively communicates with the light transmissive portion of the upper portion. The light pipe extends at least partially into the chamber and has an open, lower free end. When whole blood filling the rotor chamber contacts the lower free end of the light pipe, the red color of the blood is transmissively communicated to the upper portion of the rotor housing where it is viewable by the user of the centrifuge.

Abstract: A centrifugal processing bag, system and method for separating the components of a mixed material is presented. The processing bag includes a hub and a first port for receiving the mixed material, where the first port includes an outlet positioned within the processing bag at a perimeter of the bag. The processing bag also including a second port having a second port inlet spaced proximate the hub and away from a central axis of the hub. The second port directs a separated material collected from the second port inlet out of the processing bag.

Abstract: A centrifuge tube assembly includes an elongate tubular receptacle having a capped upper end. The capped upper end includes a single inlet/outlet port formed therethrough for communication with an interior of the tubular receptacle. A flexible aspiration pipe is communicably engaged with the inlet/outlet port for extending longitudinally through the cylindrical receptacle. A sealing diaphragm is attached to a distal end of the pipe. The diaphragm is longitudinally movable within the tubular receptacle and sealably interengages an interior wall of the receptacle. Biological products are introduced into and aspirated from the receptacle below the diaphragm by the fluid conducting pipe.

Abstract: A microfluidic device (1) comprising a hydrophilic microchannel structure (2) in which there is a functional unit that comprises a microconduit I (17) in which there is an inlet end (16), an outlet end (18), and a capillary stop function I (24) in the form of a local non-wettable surface area (44). The capillary stop function (24) defines a segment of microconduit I (17). Microconduit I (17) is within at least a part of this segment (46) divided into two or more microchannels (42). A part of the non-wettable surface area (44a,b) is associated with an inner wall of each of the microchannels (42).

Abstract: Disclosed herein are sample preparation devices, such as pipette tips useful for associating and releasing biological molecules.

Abstract: A microfluidic device comprising a hydrophilic microchannel structure in which there is a functional unit that comprises a microconduit which a) is intended for the transportation of liquid aliquots, and b) has an inlet end and an outlet end between which there is a capillary valve I, which preferably is based on the presence of a local non-wettable surface area. Microconduit I further comprises one or more additional capillary valves, typically one. At least one of the additional valves is upstream of capillary valve I, such as at the inlet end of the microconduit.

Abstract: Disclosed herein are sample preparation devices, such as pipette tips and pipette tip extenders, for example, useful for associating and releasing analytes.

Abstract: For containing a biological fluid and draining a constituent of the biological fluid, a kit includes a barrel, a piston assembly, a removable element, which is configured to move the piston assembly, a drainage element, which interacts with the piston assembly, and an interacting element, which interacts with the piston assembly. The kit allows for fluid separation without risk of contamination from the biological fluid itself or contamination of the biological fluid itself. Further, the kit offers the advantage of involving no needles or other sharp elements.

Abstract: A support device for a cytocentrifuge sample container includes a support body including spaced edge fingers and a clip hinged to the support body. The clip has a latch for each spaced edge finger of the support body and edge members each including lugs engaging slotted ledges in the sample container.

Abstract: A rotor includes a plurality of holding cavities for holding specimen containers, respectively. A transverse cross sectional shape of the holding cavity is a substantially triangular shape having one vertex on an inner circumference side of the rotor. Two vertices of the substantially triangular shape are arranged on an outer circumference side of the rotor so as to have equidistance from a rotary shaft of the rotor. Spacing between sides of the substantially triangular shape in a circumferential direction of the rotor gradually increase over 60% or more a radial length of the holding cavity from an innermost circumferential position to the outer circumference side of the rotor when viewed in its transverse plane.