Means Is Conveyor And Rack Patents (Class 422/65)
  • Patent number: 11878826
    Abstract: A tube filling machine (1) adapted to fill different types of empty tubes (18) simultaneously, where the filling machine (1) comprises a grouping device (11), a transfer device (9), a conveyor (7) and a filling device (2) comprising a plurality of filling nozzles (3, 4, 5, 6), where the grouping device (11) comprises a first supply tray (13) with a first type of tubes, a second supply tray (14) with a second type of tubes, a receiving tray (17) and a pick-up head (12), where the transfer device (9) is adapted to transfer a grouped row of empty tubes (18) from the receiving tray (17) to the conveyor (7), where the grouping device (11) is adapted to place a plurality of groups (21) of empty tubes adjacent each other in the receiving tray (17), where a group (21) comprises a row of the first type of tubes and a row of the second type of tubes, that the transfer device (9) is adapted to transfer a row of grouped empty tubes from the receiving tray (17) to the conveyor (9), and where the filling nozzles (3, 4, 5,
    Type: Grant
    Filed: November 27, 2020
    Date of Patent: January 23, 2024
    Assignee: Norden Machinery AB
    Inventor: Jan Nilsson
  • Patent number: 11879902
    Abstract: An object of the present invention is to provide a test method capable of efficiently performing a step of evaluating a surface state of a dispensing probe provided in a dispensing apparatus. In the test method according to the present invention, a first solution in which a coloring matter is dissolved is dispensed to a first container in advance by a first dispensing probe, a second solution in which a coloring matter is not dissolved is dispensed to a second container in advance by the first dispensing probe and then the first solution and the second solution are respectively sucked and discharged by a second dispensing probe. After that, a surface state of the second dispensing probe is evaluated by acquiring an amount of the coloring matter collected by the second solution (see FIG. 2).
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: January 23, 2024
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Akihiro Nojima, Takamichi Mori, Isao Yamazaki, Tetsuji Kawahara, Youichi Aruga
  • Patent number: 11879836
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating a first light wave by an emitter of the sensor system and detecting a second light wave by a detector of the sensor system. The second light wave is detected in response to the first light wave being reflected from a target object. The sensor system includes a first converter that obtains a first temperature measurement from a temperature sensor of the sensor system at least when the first light wave is generated or when the second light wave is detected. A temperature controller computes temperature coefficients to regulate a temperature of the sensor system. Each of the temperature coefficients are computed based on a difference between the first temperature and a reference temperature. The temperature controller generates a control signal to regulate the temperature of the sensor system based on the computed temperature coefficients.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: January 23, 2024
    Assignee: ams Sensors Germany GmbH
    Inventors: Dalibor Stojkovic, Predrag Micakovic
  • Patent number: 11879766
    Abstract: A droplet dispensing apparatus includes a crystal sensor, a resonance frequency measuring unit, and a controller. The controller is configured to obtain the resonance frequency of the crystal sensor before droplets are discharged from a liquid dropping device, control the liquid dropping device to discharge droplets on to the crystal sensor, and obtain the resonance frequency of the crystal sensor after droplets are discharged from the liquid dropping device. The controller estimates a volatilization amount for the droplets on the crystal sensor based on a temporal change trend in the resonance frequency of the crystal sensor and calculates the total weight of the droplets discharged from the liquid dropping device based on the difference in resonance frequency of the crystal sensor before and after the droplets are discharged and the estimated volatilization amount.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: January 23, 2024
    Assignee: Toshiba Tec Kabushiki Kaisha
    Inventors: Shuhei Yokoyama, Atsushi Kubota, Ryutaro Kusunoki
  • Patent number: 11879880
    Abstract: Machines and methods are for performing fully-automated biological evaluation and chemical analysis. A pretreatment module is used in treatments of enriching, concentrating and purifying a sample to be analyzed. A component separation module is used for carrying out separation of multiple compounds in mother liquor to be analyzed. A monitoring and identifying module is for monitoring and collecting chromatographic signals of the separated liquid effluent in real time, as well as quantitative detection of suspicious compounds. A component collection module is used in operations of collecting, transferring and dissolving, redissolving, and pipetting the separated liquid effluent. A biological evaluation module is for cell culture and detection of cytotoxic effect and toxic targets. A data processing and automated control module is for acquisition, arrangement and analysis of the integrated data.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: January 23, 2024
    Assignee: Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences
    Inventors: Guangbo Qu, Qianchi Ma, Yanna Liu, Jianbo Shi, Guibin Jiang
  • Patent number: 11865713
    Abstract: A suspension cable robot is provided, its stability can be improved by using at least three groups of three cables arranged in a parallelogram manner. The ability to remain stable when subjected to forces acting on the robot platform or end effector is thereby significantly increased. The cable robot can be moved by cables to different working locations.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: January 9, 2024
    Inventor: Frédéric Vachon
  • Patent number: 11869636
    Abstract: An analysis instrument comprises a sample receiving section for receiving samples provided by a plurality of users, an analysis section operable to receive an aliquot of each received sample, perform an analysis of each received aliquot, and generate an output based on the analysis, and a presentation section adapted to present the output in a human discernable format. The analysis instrument further includes an identification section adapted to autonomously generate an identifier unique to each user and each sample provided thereby and to supply each identifier for presentation by the presentation section in a human discernable format together with a portion of the output that corresponds with one or more samples provided by a user to which the identifier is unique. Each identifier consists of one or more graphic symbols, one or more colours, and/or one or more numbers.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: January 9, 2024
    Assignee: FOSS Analytical A/S
    Inventors: Rasmus Lundgaard Christensen, Tamir Gil, Rasmus Vistisen, Malin Damm
  • Patent number: 11867710
    Abstract: Aspects of the present disclosure relate to a method and/or a device for carrying out chemical, biochemical and/or immunochemical analyses of liquid samples, which are present in a sample store of an automatic analyzer, with the aid of liquid reagents which are present in at least one reagent store of the analyzer, with cuvettes for receiving the liquid samples and reagents, wherein a plurality of cuvettes is arranged as at least one stationary, linear cuvette array in the analyzer. The analyzer has movable and stationary automated components, wherein at least two automated components are designed so as to be movable in the x-direction independently of one another along or parallel to the line of movement defined by the linear cuvette array and each have access to different cuvettes or groups of cuvettes in a freely selectable sequence.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: January 9, 2024
    Assignee: Meon Medical Solutions GmbH & Co KG
    Inventors: Berthold Limbach, Arnold Bartel, Herfried Huemer, Reinhard Marik, Patrick Kraus-Füreder, Robert Scholz-Mareich, Wolfgang Sprengers
  • Patent number: 11852645
    Abstract: A wash system for use in an in vitro diagnostic immunoanalyzer utilizes a bridge having a linear track to move cuvettes from one incubation ring portion to another incubation ring portion. Washing stations along the linear track provide a magnetic field and fluid washing of cuvette contents independent of the size and motion of one or more incubation rings.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: December 26, 2023
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Ayman Ismail, Eric Gerolstein, Brian Bolger
  • Patent number: 11856177
    Abstract: Apparatuses and a method for plate-based oligonucleotide synthesis are disclosed. In one example, an apparatus used in oligonucleotide synthesis includes a machined block to receive a commercially-available synthesis plate. A keeper is used to apply pressure to the commercially-available synthesis plate, and a sealing element is used to seal the commercially-available synthesis plate to the machined block. Other methods and apparatuses are disclosed.
    Type: Grant
    Filed: March 6, 2023
    Date of Patent: December 26, 2023
    Inventors: Bruce Erickson, Marshall Henry
  • Patent number: 11835534
    Abstract: Disclosed is an automatic cleaning and separating device for removing uncombined components in reactants in a reaction container. The automatic cleaning and separating device includes: a liquid injection and uniform mixing mechanism, a removal assembly and a liquid suction mechanism; wherein a liquid injection driver is mounted on the liquid injection and uniform mixing mechanism, a liquid suction driver is mounted on the liquid suction mechanism, the liquid injection driver drives the liquid injection and uniform mixing mechanism to move up and down so as to complete liquid injection, the liquid suction driver drives the liquid suction mechanism to move up and down to complete liquid suction, and the removal assembly removes the reaction container from the liquid injection and uniform mixing mechanism under the relative motion of the liquid suction mechanism and the liquid injection and uniform mixing mechanism.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: December 5, 2023
    Assignee: SHENZHEN INCRECARE BIOTECH CO. LTD
    Inventor: Zhen Zhang
  • Patent number: 11828765
    Abstract: An automatic analysis apparatus of the present invention includes: a measurement section that measures a sample; a remaining quantity detecting section that detects that a remaining quantity of a consumable article used in the measurement section has become less than or equal to a predetermined quantity that is set in advance; a setting section that is capable of setting in which mode, of a first mode and a second mode applied for operation control of the measurement section, to operate the measurement section for each consumable article when the remaining quantity detecting section detects that the remaining quantity of the consumable article has become less than or equal to the predetermined quantity; and a control section that controls operation of the measurement section based on the setting of the setting section.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: November 28, 2023
    Assignee: JEOL Ltd.
    Inventors: Tamami Kaneda, Makoto Asakura
  • Patent number: 11793432
    Abstract: A biological fluid collection device that is adapted to receive a blood sample is disclosed. The biological fluid collection device includes a housing, a puncturing element transitionable between a pre-actuated position wherein the puncturing element is retained within the housing and a puncturing position wherein at least a portion of the puncturing element extends through the housing, and a cartridge removably connectable to a portion of the housing. After collecting a blood sample, the cartridge is removable from the housing and the cartridge is able to transfer the blood sample to a point-of-care testing device. The biological fluid collection device provides a closed system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer.
    Type: Grant
    Filed: January 18, 2021
    Date of Patent: October 24, 2023
    Assignee: Becton, Dickinson and Company
    Inventors: Bradley M. Wilkinson, C. Mark Newby
  • Patent number: 11794190
    Abstract: There is an apparatus (1) and a method for providing visual signals relating to a plurality of laboratory sample carriers (2). Laboratory sample carriers (2) are placed on corresponding carrier bays (6) of a tray (4) wherein each sample carrier (2) displays an identification code (5). A digital image of at least part of the tray (4) is taken with a digital camera (11). The digital image is processed with a processing device (13) to read the laboratory sample carrier identification codes (5) in the image. A visual signal emitting device (10) is activated to emit at least one visual signal for each occupied carrier bay (6) included in the image wherein the visual signal emitted for each carrier bay (6) is determined by the sample carrier identification code (5) read by the processing device (13) from a corresponding carrier bay part of the processed image.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: October 24, 2023
    Assignee: Pyramid Innovation Ltd
    Inventor: Thomas Fergus Hughes
  • Patent number: 11774331
    Abstract: A system having a first automatic machine (1) for processing or investigating biological samples and a second automatic machine (16) for processing or investigating biological samples. The first machine (1) and the second machine (16) are electrically connected to an electrical power grid in order to be supplied with electrical energy as an electrical load. The first machine (1) has a first control apparatus (13) and the second machine (16) has a second control apparatus (19), which detect disruptions in the supply of electrical energy from the power grid and, in the event of a disruption, switch over to a withdrawal of electrical energy from a first energy reservoir (12) or a second energy reservoir (18). The first machine (1) and the second machine (16) are also electrically connected to each other, such that the electrical energy is transferrable from an energy store of one of the automatic machines to the other automatic machine.
    Type: Grant
    Filed: February 16, 2022
    Date of Patent: October 3, 2023
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Benjamin Siehl, Markus Sharpe, Markus Wittmann
  • Patent number: 11761027
    Abstract: A system includes a reagent pack input carousel, a carousel frame supporting the carousel, and a track on which the carousel frame is supported for movement of the carousel into and out of an instrument in drawer-like fashion. The carousel is rotatable about an axis of rotation and includes a plurality of reagent pack input stations arranged about the perimeter of the carousel. Each input station is adapted to carry a reagent pack, and the input stations are oriented at an angle with respect to a radial orientation relative to the axis of rotation. Each input station includes an alignment block located at a radially inner end of the station, and the block is received within a recess formed in an end of the reagent pack placed in the station to align and position of the reagent pack within the station.
    Type: Grant
    Filed: July 29, 2022
    Date of Patent: September 19, 2023
    Assignee: GEN-PROBE INCORPORATED
    Inventors: David A. Buse, Norbert D. Hagen, David Opalsky
  • Patent number: 11738337
    Abstract: In certain embodiments, the disclosure provides an inflatable bladder lid that configures with a cartridge configured for assay testing. The inflatable bladder provides substantially uniform pressure to the cartridge. The pressure is substantially distributed across the one or more regions of the cartridge to extend pressure over a wide cartridge surface. At least a portion of the bladder lid may comprise a flexible membrane material that inflates and stretches over at least a portion of the cartridge to conformally contact its first/top surface.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: August 29, 2023
    Assignee: ANCERA INC.
    Inventor: Hur Koser
  • Patent number: 11732288
    Abstract: An assembly includes a bracket, a magnetic elution slot, and a reagent pack loading station. The elution slot receives a multiple receptacle device having multiple receptacles interconnected by a connecting rib defining shoulders along either side of the receptacle device. The elution slot includes opposed walls attached to the bracket below a top surface of the bracket with the opposed walls disposed on either side of a slot formed in the bracket. The downwardly facing shoulders of the receptacle device are supported on the top surface of the bracket on opposed sides of the slot, and one or more magnets are attached to or embedded in one or both walls. The reagent pack loading station holds a multi-well reagent pack such that the wells of the reagent pack are accessible by a pipettor, and the reagent pack holding station includes spaced apart hold down features extending above the top surface of the bracket.
    Type: Grant
    Filed: July 29, 2022
    Date of Patent: August 22, 2023
    Assignee: GEN-PROBE INCORPORATED
    Inventors: David A. Buse, Norbert D. Hagen, David Opalsky
  • Patent number: 11709173
    Abstract: Disclosed are high-throughput vessel supply systems and methods of supplying sample vessels, such as samples stored in test tubes. A system for supplying a plurality of individual vessels that each contains a sample is disclosed.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: July 25, 2023
    Assignee: Laboratory Corporation of America Holdings
    Inventors: David Wilson, Jay Krajewski, Kevin Meyer
  • Patent number: 11679933
    Abstract: An automated biological or chemical sample processing system includes a dock frame and at least one dock frame module. The dock frame includes at least one docking interface that operably couples and interfaces the dock frame with laboratory equipment. The dock frame defines a spine structure of the system alongside which a variable number of laboratory equipment are arrayed. The dock frame extends longitudinally and has a variable elongated configuration and longitudinal length. The at least one dock frame module includes the docking interface, where each module is interchangeable with another module, and has control features with a predetermined relationship to a reference datum of the dock frame module and with a reference datum of the dock frame so that the at least one dock frame module is interchangeably coupled in linear configuration with at least the other dock frame module to select the variable elongated configuration and longitudinal length.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: June 20, 2023
    Assignee: HIGHRES BIOSOLUTIONS, INC.
    Inventors: Louis Guarracina, Ulysses Gilchrist
  • Patent number: 11673142
    Abstract: A device for the handling and the low-temperature storage of probe tubes in tube racks includes a low-temperature compartment having insulated side and bottom walls and at least one opening at a top side. The compartment is used for storing at least one tube rack at a low temperature. The device has a holder apparatus comprising a rack holder for holding a tube rack and a picker apparatus comprising a gripper adapted to remove and insert individual tubes from or into a tube rack held by the holder. The holder apparatus is adapted to displace the rack holder between an upper rack position outside low-temperature compartment above the opening and a lower rack position inside the compartment. The picker apparatus is adapted to displace the gripper between an upper gripper position outside the compartment above the opening and a lower gripper position inside the compartment below the opening.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: June 13, 2023
    Assignee: LICONIC AG
    Inventor: Cosmas G. Malin
  • Patent number: 11648565
    Abstract: The equipment item for automatically managing a plurality of biological samples placed in a respective sample jar includes a storage container for sample jars having a plurality of housings, an apparatus with a reader of encoded identification data affixed on the sample jars placed in the container, a device for determining data representative of the position of each sample jar within the container, and a device for rotating the container, and a computer processor connected to the apparatus. The container includes, in the immediate vicinity of each housing, a shape appearing recessed or raised, while the device for determining data representative of the position of each sample jar is defined by a detector for the shape.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: May 16, 2023
    Assignee: DREAMPATH DIAGNOSTICS
    Inventors: Pablo Jordan Navas, Valerie Wilhelm
  • Patent number: 11639942
    Abstract: A sample analyzer, comprising a sample storage region, a sample-drawing channel, and a transport mechanism; the sample storage region being provided with a plurality of storage channels; the sample-drawing channel is provided with a sample-drawing position; the transport mechanism comprises an engagement slot, an actuation mechanism and a first moving mechanism; the engagement slot and the actuation mechanism are fixed on the first moving mechanism, the actuation mechanism comprises an actuator and a second moving mechanism, the actuator is drivable by at least one of the first moving mechanism and the second moving mechanism to realize the movement of the sample holder between the storage channels and the engagement slot; during sample drawing, the first moving mechanism drives the engagement slot to move to the sample-drawing channel, the actuation mechanism enables samples to pass through the sample-drawing position and to make a stop for sample drawing.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: May 2, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Zhihong Wang, Fating She, Peng Zhou
  • Patent number: 11641695
    Abstract: An aerosol-generating system may include a liquid storage portion configured to hold aerosol-forming substrate, a vaporizer, and a pump. The liquid storage portion includes a movable wall and an outlet. The vaporizer includes a heating element having a structure that at least partially defines an internal passage. The pump may deliver liquid aerosol-forming substrate from the outlet of the liquid storage portion to the internal passage of the heating element. The pump may include a micro stepper motor with a drive shaft that is configured to rotate a particular amount based on performing an individual step, a piston connected to the movable wall, and a lead screw connecting the drive shaft to the piston and configured to translate rotation of the drive shaft into axial movement of the piston and the movable wall. The vaporizer may at least partially vaporize the delivered liquid aerosol-forming substrate.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: May 2, 2023
    Assignee: Altria Client Services LLC
    Inventors: Rui Nuno Batista, Ben Mazur
  • Patent number: 11639943
    Abstract: There is provided an automatic analysis device that can easily realize introduction and replacement of additional reagents in operation even in a small-scale configuration. The automatic analysis device includes a reagent dispensing mechanism 107 that dispenses a reagent from a reagent container 113 containing a reagent, and a normal reagent storage portion 130 that stores a reagent container and an additional reagent storage portion 111. The normal reagent storage portion 130 is positioned in a normal movable area 132, which is a portion of a movable area 131 of the reagent dispensing mechanism 107 and the additional reagent storage portion 111 is positioned in an area excluding the normal movable area 132 in the movable area 131 of the reagent dispensing mechanism 107.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: May 2, 2023
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Kenta Imai, Hiroya Umeki, Shunsuke Sasaki, Yoshihiro Yamashita, Taku Sakazume
  • Patent number: 11635443
    Abstract: Aspects of the present disclosure relate to a method and/or a device for carrying out chemical, biochemical and/or immunochemical analyses of liquid samples, which are present in a sample store of an automatic analyzer, with the aid of liquid reagents which are present in at least one reagent store of the analyzer. In one example embodiment, the automatic analyzer includes cuvettes, a first pipettor, a device with an optical measurement unit, a device for heterogenous immunoassays, a cuvette washing unit, a needle washing unit, a temperature control unit.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: April 25, 2023
    Assignee: MEON MEDICAL SOLUTIONS GMBH & CO KG
    Inventors: Berthold Limbach, Arnold Bartel, Herfried Huemer, Reinhard Marik, Patrick Kraus-Füreder, Robert Scholz-Mareich, Wolfgang Sprengers
  • Patent number: 11619642
    Abstract: The invention discloses a reaction incubation device, an immunity analyzer and a reaction incubation method. The reaction incubation device comprises a reaction unit (10), which is used for bearing and incubating a reaction container; and a transfer unit (20), which is used for removing the reaction container in and out of the reaction unit (10). The reaction unit (10) comprises a rotating device (11). The rotating device (11) is provided with an incubation position which increases a predetermined angle ? at an interval of fixed time T along with the rotating device (11). The transfer unit (20) removes the reaction container out of the incubation position according to variable incubation time ti. With the device, flexible and variable incubation time can be achieved, and the problem of complicated control, low reliability and that high-speed automation is not easy to achieve in the prior art can be solved.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: April 4, 2023
    Assignee: Shenzhen Increcare Biotech Co., Ltd.
    Inventor: Zhen Zhang
  • Patent number: 11598784
    Abstract: This invention relates to an apparatus for conducting immunoassay test. The apparatus includes a groove unit having a groove along a vertical direction configured to hold a rod-shaped portion of a probe along the vertical direction, and a push pin configured to move along a horizontal direction, the push pin being capable of residing at a first position and a second position. A tip of the push pin is capable of pressing the rod-shaped portion of the probe against the groove when the push pin resides at the first position. The distance between the tip of the push pin and the groove is larger than a diameter of the rod-shaped portion of the probe when the push pin resides at the second position.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: March 7, 2023
    Assignee: Access Medical Systems, LTD.
    Inventors: Hong Tan, Ming Xia, Yushan Tan, Jun Chen, Erhua Cao, Genqian Li, Robert F. Zuk
  • Patent number: 11592365
    Abstract: A smear preparing apparatus that operates under selectable operation modes, may include: a smearing unit that prepares smeared slides by smearing samples onto slides; a staining unit that is capable of housing the smeared slides and that performs staining processing by accommodating a staining solution used to stain the samples on the housed smeared slides; a fluid circuit that supplies the staining solution to the staining unit; and a controller that controls the supplying of the staining solution to the staining unit depending on a selected one of the operation modes.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: February 28, 2023
    Assignee: SYSMEX CORPORATION
    Inventors: Junya Ikuta, Masaharu Shibata, Noriyuki Nakanishi, Mitsuo Yamasaki, Yuji Takano, Ken Nishikawa
  • Patent number: 11585822
    Abstract: According to an example aspect of the present invention, there is provided a method of information transmission in a system comprising at least one liquid handling device and at least one external device, the method comprising: in one or more of said at least one liquid handling device, producing a machine-readable code that contains information that is derived from a status or properties of the respective liquid handling device or information that has been stored in the respective liquid handling device; in said one or more of said at least one liquid handling device, displaying the respective code on a display that is integrated to a structure of the respective liquid handling device; reading the displayed code or one or more of the displayed codes by an external device.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: February 21, 2023
    Assignee: Sartorius Biohit Liquid Handling Oy
    Inventors: Iiro-Pekka Eerola, Jouni Valtonen
  • Patent number: 11584556
    Abstract: The present invention relates to a method and a system (400) for filling a closed container (200) with a fixative solution. The system comprises a container (200) comprising a container body (230) for receiving a biological specimen, a lid (220) for selectively closing the container body (230) and a port (100) forming a unidirectional barrier in a direction from the inside (IC) to the outside (OC) of the closed container (200). The system further comprises a dispensing apparatus (500) having a filling nozzle (300) for dispensing the fixative solution. The filling nozzle (300) is relatively moveable with respect to the container (200) between a retracted position and a filling position to fill the container (200) with the fixative solution.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: February 21, 2023
    Assignee: MILESTONE S.R.L.
    Inventors: Francesco Visinoni, Matteo Minuti, Marco Bellini, Michele Bellini, Michele Martinelli
  • Patent number: 11574460
    Abstract: Systems and methods are provided for recognizing various sample containers carried in a rack. The systems and methods are performed to identify sample containers in the rack and detect various characteristics associated with the containers and/or the rack, which are evaluated to determine the validity and/or types of the containers in the rack.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: February 7, 2023
    Assignee: BECKMAN COULTER, INC.
    Inventors: Amit Sawhney, Niandong Liu, Nobuyuki Hakiri
  • Patent number: 11543405
    Abstract: An environmental sampling and assay system, having a coupon storage assembly, storing coupons; an environment sampling assembly, the sampling assembly mixing an environmental sample with a liquid to create a sample-liquid, bearing the environmental sample; a coupon moving assembly; a coupon wetting assembly for automatically wetting a coupon with the sample-liquid; a coupon perceiving device; a data input, adapted to receive a signal; and a data processing and control assembly, controlling the environmental sampling system, the coupon moving assembly, the wetting assembly and the coupon perceiving device. Further, the coupon moving assembly can retrieve a coupon from the coupon storage assembly and move it in a linear manner to the coupon wetting assembly.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: January 3, 2023
    Assignee: CBRN INTERNATIONAL, LTD.
    Inventors: Elric Saaski, Robert Fay Livingston, Duane M. Fox
  • Patent number: 11534766
    Abstract: A tissue processing system for processing a laboratory slide includes a slide holder for holding the slide, an outlet port positioned to direct a fluid stream onto the slide, and a device for moving the slide holder relative to the outlet port, or vice versa, to adjust a point on the slide at which the fluid stream is delivered onto the laboratory slide. The slide holder includes an absorbent pad configured to be positioned between one wall of the plurality of walls and a free edge of the slide for absorbing fluid travelling along the slide. A manifold of the system includes a first outlet port that directs a first fluid stream from a first fluid passageway onto the slide, and a second outlet port that directs a second fluid stream from a second fluid passageway onto a location of the slide that differs from the first fluid stream.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: December 27, 2022
    Assignee: Rushabh Instruments, LLC
    Inventors: Preyas Shah, Sahil Shah
  • Patent number: 11506675
    Abstract: The purpose of the present invention is to embody an inspection device wherein dew condensation in a sample container, in particular, in the lid thereof can be prevented or quickly removed without giving heat shock to a sample in the sample container. For this purpose, provided is an inspection device comprising an isothermal part 110 which comprises a rack 111 and maintains a sample container 150 storing a sample in a temperature-controlled environment, said sample container 150 comprising a plate and a lid, a detection part 120 which comprises an optical device for observing and inspecting the sample stored in the sample container, and a transportation part 130 which transports the sample container from the isothermal part to the detection part and vice versa, wherein at least one of the isothermal part, detection part and transportation part is provided with a member by which the lid of the sample container is held in a state lifted from the plate.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: November 22, 2022
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Akira Masuya, Hiroko Fujita
  • Patent number: 11499947
    Abstract: A sample introduction device 10 includes a tube holding section 21 and a sample removing mechanism 40. The sample removing mechanism 40 removes a sample 6 in a sample tube 2 held by the tube holding section 21. Thus, in the sample introduction device 10, the sample 6 in the sample tube 2 held by the tube holding section 21 can be automatically removed. As a result, the operator no longer needs to perform an operation of taking out the sample 6 from the sample tube 2. Thus, a work load on the operator can be reduced.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: November 15, 2022
    Assignee: SHIMADZU CORPORATION
    Inventors: Isao Sawamura, Akira Aono
  • Patent number: 11486887
    Abstract: The present invention is provided with a sample rack insertion unit 12 that is capable of holding one or more sample racks 5 having mounted therein one or more sample containers 6 accommodating a sample to be analyzed, one or more analysis devices 2, 3 for analyzing the sample accommodated in the sample containers 6, a sample rack conveyance unit 14 for conveying the sample racks 5 from the sample rack insertion unit 12 to the analysis devices 2, 3, and a control device 4 for acquiring, for each analysis device 2, 3, load information that is information expressing an operating condition of the analysis device 2, 3, and, if there is an analysis device 2, 3 for which the load information is larger than a predetermined conveyance permission value, carrying out control so as to stop the conveyance of the sample racks 5 from the sample rack insertion unit 12 to the analysis device(s) 2, 3.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: November 1, 2022
    Assignee: Hitachi High-Tech Corporation
    Inventors: Masashi Akutsu, Akihisa Makino, Hiroyuki Mishima, Akihiro Yasui
  • Patent number: 11448624
    Abstract: An ionization probe connection jig used to connect an outlet-side flow path of a column 113 and an inlet-side flow path of an ionization probe 211 in a liquid chromatograph, the ionization probe connection jig includes: a first element fixture 10 fixed to a first element 113 that is one of the column 113 and the ionization probe 211; a second element fixture 20 fixed to a second element 211 that is the other; and a movement regulating tool 30 that permits the first element fixture 10 to advance in an axial direction of the first element 113 while regulating the first element 113 or the first element fixture 10 and the second element 211 or the second element fixture 20 such that flow paths of the first element 113 and the second element 211 are matched with each other, and regulates the second element fixture 20 such that the second element fixture 20 does not retreat beyond a predetermined position in a axial direction of the second element 211.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: September 20, 2022
    Assignee: SHIMADZU CORPORATION
    Inventor: Wataru Fukui
  • Patent number: 11439971
    Abstract: The present invention provides an automated modular system and method for production of biopolymers including DNA and RNA. The system and method automates the complete production process for biopolymers. Modular equipment is provided for performing production steps with the individual modules arrange in a linear array. Each module includes a control system and can be rack mounted. One side of the array of modules provides connections for power, gas, vacuum and reagents and is accessible to technicians. On the other side of the array of modules a robotic transport system is provided for transporting materials between module interfaces. The elimination of the requirement for human intervention at multiple steps in the production process significantly decreases the costs of biopolymer production and reduces unnecessary complexity and sources of quality variation.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: September 13, 2022
    Assignee: Synthego Corporation
    Inventors: Paul Dabrowski, Michael Dabrowski, Fabian Gerlinghaus, Alex Pesch
  • Patent number: 11435369
    Abstract: In one embodiment, a biological sample analyzer has a housing having at least one outer wall that defines a cavity therein. A receptacle, which can support a consumable holder containing a biological sample, is disposed within the internal cavity. At least one heater applies heat to the receptacle when the consumable holder is supported by the receptacle. At least one heater sensor detect temperatures of the receptacle over time. A controller detects whether the consumable holder is below an ambient temperature based on a decrease in temperature of the receptacle when the consumable holder is inserted into the receptacle. The controller also increases an amount of thermal energy transferred from the at least one heater to the consumable holder when the controller detects that the consumable holder is below the ambient temperature so as to heat the consumable holder to a target temperature.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: September 6, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: George Zantos, George Yeung
  • Patent number: 11402305
    Abstract: A smear staining apparatus may include: a chamber part in which glass slides can be placed and that is configured to contain a staining solution for staining a smear on each of the glass slides; a cover part that covers the chamber part from above and comprises an insertion hole through which the glass slides are transported to the chamber part; and a transport part that transports the glass slides to the chamber part through the insertion hole.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: August 2, 2022
    Assignee: SYSMEX CORPORATION
    Inventors: Takaaki Nagai, Noriyuki Nakanishi, Seiya Shinabe, Tetsuya Oda, Mitsuo Yamasaki, Hiroyuki Koga
  • Patent number: 11378583
    Abstract: An analyzer system for in vitro diagnostics includes a sample handler module having a robot arm that delivers samples from drawers into carriers on a linear synchronous motor automation track. Samples are delivered via the automation track to individual track sections associated with individual analyzer modules. Analyzer modules aspirate sample portions directly from the sample carriers and perform analysis thereon.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: July 5, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: David Stein, Roy Barr, Mark Edwards, Colin Mellars, Thomas J. Bao, Charles V. Cammarata, Benjamin S. Pollack, Baris Yagci, Beri Cohen
  • Patent number: 11307210
    Abstract: The invention relates to a conveying device (IO) for positioning and providing laboratory vessels (12; 12a, 12b, 12c) for nutrient media, samples, microorganisms, cell cultures, or the like for analysis, sample preparation, and/or sample manipulation at an associated apparatus (64), comprising at least one first conveying unit (32) for conveying the laboratory vessels (12) between an initial region (30) and a provision region (60), where the laboratory vessel (12) is held for the analysis or preparation. According to the invention, a plurality of conveying units is present, which perform only a translational motion of the laboratory vessel (12) along an axis, wherein the first conveying unit (32) vertically conveys the laboratory vessel (12) from the initial region (30) to a predetermined height region (50) and vice versa, and a second conveying unit (56) is provided, which horizontally conveys the laboratory vessel (12) from the height region (50) to the provision region and vice versa.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: April 19, 2022
    Assignee: ANDREAS HETTICH GMBH & CO. KG
    Inventor: Klaus-Guenter Eberle
  • Patent number: 11249095
    Abstract: An automated system is provided for performing slide processing operations on slides bearing biological samples. In one embodiment, the disclosed system includes a slide tray holding a plurality of slides in a substantially horizontal position and a workstation that receives the slide tray. In a particular embodiment, a workstation delivers a reagent to slide surfaces without substantial transfer of reagent (and reagent borne contaminants such as dislodged cells) from one slide to another. A method for automated processing of slides also is provided.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: February 15, 2022
    Assignee: Ventana Medical Systems, Inc.
    Inventors: Kurt Reinhardt, Charles D. Lemme, Glen Ward, William L. Richards, Wayne Showalter, Brandon Ambler, Austin Micheil Ashby, Chris Borchert, Devon C. Campbell, Kimberly Christensen, Matthew Freeman, Andrew Ghusson, Rick Griebel, Kendall B. Hendrick, Miroslav Holubec, Parula Mehta, Vince Rizzo
  • Patent number: 11237181
    Abstract: The conveying system includes a support guide element defining a guide track, the support guide element being configured to receive a containers support and guide said containers support in translation along the guide track; and a self-propelled conveying carriage displaceable along a conveying track extending along the support guide element, the self-propelled conveying carriage comprising a drive element movably mounted between at least one drive position in which the drive element is configured to transmit a drive movement to the containers support received on the support guide element, and a release position in which the drive element is configured to release the containers support, the self-propelled conveying carriage being configured to displace the containers support in translation along the guide track when the drive element is in the drive position and the self-propelled conveying carriage is displaced along the conveying track.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: February 1, 2022
    Assignee: ARTEION
    Inventor: Alain Rousseau
  • Patent number: 11231430
    Abstract: An instrument for processing a biological sample includes a chassis. Connected to the chassis is a tape path along which a tape with a matrix of wells can be automatically advanced through the instrument, a dispensing assembly for dispensing the biological sample and a reagent into the matrix of wells of the tape to form a biological sample and reagent mixture, a sealing assembly for sealing the biological sample and reagent mixture in the tape, and an amplification and detection assembly for detecting a signal from the biological sample and reagent mixture in the matrix of wells in the tape.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: January 25, 2022
    Assignee: Douglas Scientific, LLC
    Inventors: Darren Lynn Cook, Eric Guy Johnson, Nathan Luther Westad, Andrew Richard Haug, James Henry Konynenbelt, Grant Edward Maasjo, Jared Whittier Patterson, Brent Conrad Urke, Ryan John Zitzmann, Chad Steven Smith
  • Patent number: 11215625
    Abstract: A sample vessel is picked up from a sample carrier with a gripping device including first and second gripping sections. The first and second gripping sections grip the sample vessel from first and second sides. First and second holders for the sample vessel are provided, as is a first tool for moving the sample vessel along a stroke movement path. In the method, the first and second gripping sections are positioned on first and second sides of the sample vessel and the first tool engages with the sample vessel; the sample vessel is moved along the stroke movement path; the sample vessel is picked up in the second holder; the first and second gripping sections are repositioned in a lateral direction orthogonal to the stroke movement path such that the sample vessel is arranged in a free area not occupied by the sample carrier.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: January 4, 2022
    Assignee: HAMILTON STORAGE GMBH
    Inventor: Johann Seeber
  • Patent number: 11209450
    Abstract: A specimen inspection automation system includes holder orientation adjustment mechanisms that adjust the orientations of specimen container holders that each holds one specimen container. The holder orientation adjustment mechanisms each includes: a stopper mechanism that is disposed above a conveyance line that conveys a specimen container holder and restricts the downstream movement of the specimen container holder by abutting, at the same height as a notched part provided on one side of a base of the specimen container holder, an outer circumferential part other than the notched part in the circumferential direction of the base; and a holder rotation mechanism that restricts the movement of the specimen container holder away from the stopper mechanism and rotates the specimen container holder in the circumferential direction. As a result, it is possible to appropriately adjust the orientation of a specimen container in which a specimen is accommodated and reduce work complexity.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: December 28, 2021
    Assignee: HITACHI HIGH-TECH CORPORATION
    Inventors: Kohei Kinugawa, Katsuhiro Kambara, Toshiki Yamagata
  • Patent number: 11187694
    Abstract: An automated analyzer for reagent cards having a leading end, a trailing end and a length between the leading end and the trailing end comprises a travel surface assembly having a card travel surface and an edge. A test analyzing mechanism is adjacent to the travel surface, and a waste receptacle is adjacent to the edge below the travel surface. The waste receptacle has a side and a waste cavity. A ramp member positioned below the travel surface has an end and a sloped surface, and is movable between an extended position where the sloped surface extends into the waste cavity, and a retracted position where the end is spaced from the side a distance greater than the length of the reagent card. A moving mechanism operably coupled with the ramp member is configured to move the ramp member between the extended position and the retracted position.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: November 30, 2021
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Kenneth Galano, Michael Parker, Aaron Sung-Lien Tang
  • Patent number: 11181540
    Abstract: A measurement system according to one or more embodiments may include a measurement unit that measures a sample contained in a sample container; a transport unit including a first transporter that transports a rack holding sample containers in a longitudinal direction of the rack to the measurement unit, and a second transporter that transports the rack from the measurement unit; and a rack export-import unit that sets racks thereon, that is capable of transferring each of the set racks in a lateral direction of the rack, that exports the rack to the first transporter from one end side of the rack export-import unit, and that imports the rack transported by the second transporter from another end side of the rack export-import unit. The rack export-import unit includes a transfer prevention section that prevents the rack imported from the other end side from being transferred from the one end side.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: November 23, 2021
    Assignee: SYSMEX CORPORATION
    Inventors: Yuichiro Ohmae, Hiroo Tatsutani