Means Is Conveyor And Rack Patents (Class 422/65)
  • Patent number: 11137411
    Abstract: A sample analyzer, comprising a sample storage region, a sample-drawing channel, and a transport mechanism; the sample storage region being provided with a plurality of storage channels; the sample-drawing channel is provided with a sample-drawing position; the transport mechanism comprises an engagement slot, an actuation mechanism and a first moving mechanism; the engagement slot and the actuation mechanism are fixed on the first moving mechanism, the actuation mechanism comprises an actuator and a second moving mechanism, the actuator is drivable by at least one of the first moving mechanism and the second moving mechanism to realize the movement of the sample holder between the storage channels and the engagement slot; during sample drawing, the first moving mechanism drives the engagement slot to move to the sample-drawing channel, the actuation mechanism enables samples to pass through the sample-drawing position and to make a stop for sample drawing.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: October 5, 2021
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Zhihong Wang, Fating She, Peng Zhou
  • Patent number: 11104962
    Abstract: The instant disclosure provides methods of multi-assay processing and multi-assay analysis. Such multi-assay processing and analysis pertain to automated detection of target nucleic acids, e.g., as performed in the clinical setting for diagnostic purposes. Also provided are common assay timing protocols derived from a variety of individual nucleic acid amplification and analysis protocols and modified to prevent resource contention. The instant disclosure also provides systems and devices for practicing the methods as described herein.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: August 31, 2021
    Assignee: Abbott Molecular Inc.
    Inventors: Frank Pawlowski, Joseph P. Skinner, Jack Kessler, Sonal Sadaria Nana
  • Patent number: 11029322
    Abstract: A biochemical analyzer delivery system, comprising a sample feeding track (42), an advancing track (43), a recovery track (44), at least one to-be-tested sub-track (45), at least one emergency sub-track (46) and at least one return sub-track (47); the sample feeding track (42), the advancing track (43) and the recovery track (44) are parallel to each other; the to-be-tested sub-track (45), the emergency sub-track (46) and the return sub-track (47) are disposed between and perpendicular to the sample feeding track (42) and the advancing track (43), an emergency sample may enter the emergency sub-track via the advancing track (43), and then enters the sample feeding track for sample suction. The track-based delivery system can be horizontally disposed in a biochemical analyzer, and can be butt-jointed with a vertical track in the biochemical analyzer, thereby greatly increasing the buffer amount of sample holders without increasing the length of the biochemical analyzer.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: June 8, 2021
    Inventors: Jihua Zou, Tao Xiong, Xiaohui Wu, Shangqing Xiao, Lei Xu, Zhe Feng
  • Patent number: 10948507
    Abstract: A specimen transport apparatus according to an embodiment includes: a holder including first and second trenches and configured to hold a specimen; a first transporter including a first protrusion to engage with the first trench and configured to transport the holder by transferring the first protrusion engaged with the first trench in an extension direction of the second trench; a second transporter including a second protrusion to engage with the second trench and configured to transport the holder by transferring the second protrusion engaged with the second trench in an extension direction of the first trench. The first trench is formed in at least one of an upper surface and a lower surface of the holder. The second trench is formed in at least one of the upper surface and the lower surface of the holder, and is formed to extend to a lateral surface of the holder.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: March 16, 2021
    Inventors: Yuto Sasaki, Kazuki Asao, Kazuyuki Iguchi, Keiichiro Shohmi, Shoichiro Asada, Hiroaki Tobimatsu, Ryutaro Shinya
  • Patent number: 10942193
    Abstract: An automated positive pressure solid phase extraction apparatus and method comprising two tiered lifts devices each individually controllable to individually vertically translate within an elevator framework between a base on which the elevator framework is mounted and a manifold plate supported by the framework in a substantially horizontal plane parallel with and vertically above the two tiered lifts devices; a rectilinearly translating shuttle assembly comprising a shuttle supporting labware for rectilinear travel into and out of the elevator framework to handoff the labware to one of the two tiered elevator lifts or both; and a reagent dispensing system comprising a reagent dispensing manifold for dispensing liquids into wells of each column of wells of a labware filter plate carried by the shuttle.
    Type: Grant
    Filed: January 24, 2018
    Date of Patent: March 9, 2021
    Assignee: Hamilton Company
    Inventors: Garrett Voss, Harrison Elings
  • Patent number: 10914753
    Abstract: This sample rack conveying apparatus is provided with a pusher unit, a linear motion guide, and a conveyance drive mechanism. The pusher unit has a base portion, a moving member, and a base-side guide. The base portion is supported by the linear motion guide so as to be movable in a first guide direction. The moving member is provided with a pusher that pushes a sample rack. The base-side guide supports the moving member such that the moving member is movable in a second guide direction that crosses the first guide direction.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: February 9, 2021
    Assignee: JEOL Ltd.
    Inventor: Kenichi Sakamoto
  • Patent number: 10875205
    Abstract: A device for cutting off one or more sample regions from a sample carrier that contains impregnated sample material, e.g. blood, is described. The device includes: a cutting unit (103) for cutting off the one or more sample regions from the sample carrier, an optical imaging unit (101) for producing an electronic image of the sample carrier, and a processor (102) for controlling a display screen (108) to display the image (104) and one or more indicators (105, 105?) each expressing the location of one sample region to be cut off. Thus, an operator of the device is enabled to monitor, without direct visual communication to the sample carrier, what region or regions of the sample carrier is/are to be cut off. As no direct visual communication with the sample carrier is needed, the working ergonomics of the operator can be improved.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: December 29, 2020
    Assignee: WALLAC OY
    Inventors: Mika Olavi Routamaa, Jouni Henrik Reivolahti, Jarmo Sakari Korpi, Ilari Torsti, Kimmo Sakari Laine
  • Patent number: 10792662
    Abstract: An automated low-temperature storage for storing laboratory samples includes a storage zone for storing the samples that is maintainable at a first temperature below ?20° C.; a handling zone located above the storage zone that is maintainable at a second temperature above the first temperature and below 0° C.; a chamber laterally adjacent to the storage zone and the handling zone for storing the samples at a third temperature that is higher than the first temperature and below 0° C.; and a vertical wall separating the chamber from the handling zone and storage zone. A first opening arranged in said vertical wall connects the handling zone and the chamber; and an automated transport device is arranged at least partially in the handling zone and is configured to move the samples between the storage zone, the handling zone, and the chamber.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: October 6, 2020
    Assignee: LICONIC AG
    Inventor: Cosmas G. Malin
  • Patent number: 10788505
    Abstract: A measuring system for measuring a sample in an automated analysis machine comprises a measuring device for recording measurement values of a measured variable and a first controller and a second controller for processing the measurement values and a sliding contact system with sliding contacts, wherein the measurement values are transferred from the measuring device to the first controller and wherein the measurement values are transferred from the first controller to the second controller via the sliding contacts. The measuring system comprises an error counter which captures the errors occurring during the transfer of the measurement values from the first controller to the second controller via the sliding contacts.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: September 29, 2020
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Wolfgang Steinebach, Christian Verhalen
  • Patent number: 10768187
    Abstract: In order to easily identify a specimen to be extracted because, for example, an item remains uninspected, from a rack 31 collected in a storage part 13 or the rack 31 taken out from the storage part, a camera of a smart device takes an image of the rack; and a calculation unit included in the smart device provides a mark, by AR technology, at the position of a specimen to be extracted. For example, the item that remains uninspected is identified on the basis of information about a combination of a rack ID and an identifier and information, which is received from an operation unit about specimens at respective positions. Thus, irrespective of a place or whether the specimen to be extracted is inside or outside of the device, the specimen to be extracted can be reliably specified from a plurality of specimen containers provided on a holder.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: September 8, 2020
    Inventors: Kenichi Yasuzawa, Tsuguhiko Sato, Hiroki Mori
  • Patent number: 10647455
    Abstract: A packaging section of a tablet packaging device includes: a placement base of a tray; a drawer storing the placement bas; a carrier provided with compartments corresponding to the storage concave portions of the tray; a drive device of the carrier; a shutter opening/closing; a bottom of the carrier; and an opening/closing device of the shutter. The drive device performs a step of defining a tablet discharge position on the tray as an original position and returning to the original position through a tablet reception start position and a tablet reception end position which are set below a discharge opening. A step of sequentially moving each compartment of the carrier below the discharge opening from the tablet reception start position to the tablet reception end position during the step to receive one tray of tablets is performed. When the carrier returns to the discharge position, the shutter is opened.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: May 12, 2020
    Assignee: YUYAMA MFG. CO., LTD.
    Inventors: Yasuhiro Shigeyama, Takashi Iwatani
  • Patent number: 10624712
    Abstract: This sensitivity measuring device is provided with: a stage for placing a sample container; a temperature adjustment device that is provided with an upper heating body and a lower heating body, which are disposed above and below the sample container; and an image pickup device for picking up an image of the sample container, said image pickup device being provided with a lighting apparatus and an image pickup apparatus. Each of the upper heating body and the lower heating body has a structure wherein the temperature of a first region, a peripheral portion, is higher than the temperature of a second region including a center portion.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: April 21, 2020
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Hideaki Minekawa, Muneo Maeshima, Akira Masuya
  • Patent number: 10591428
    Abstract: The present invention relates to a sensor for detecting the presence of a botulinum neurotoxin in a sample, the sensor comprising: (a) an electrically conductive substrate coated with at least one SNAP-25, VAMP or syntaxin protein; and (b) a detection arrangement adapted to enable the detection of the cleavage of at least one SNAP-25, VAMP or syntaxin protein by the botulinum neurotoxin. The invention also relates to methods of making a sensor, methods of detecting and a detection kit for botulinum neurotoxin.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: March 17, 2020
    Inventors: Chris David Gwenin, Jennifer Helen Halliwell
  • Patent number: 10582718
    Abstract: An apparatus and a method of defrosting frozen items, is provided. The apparatus and method utilizes a fluid flow system and method, such as a fluid-push/pull system in which generally an entire volume of fluid is pushed or pulled through a cavity in which frozen items are located and/or a continuous motion system in which fluid is circulated within a fluid tank of the system.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: March 10, 2020
    Assignee: UNIFIED BRANDS, INC.
    Inventors: John W. Cantrell, Mark Churchill, Michael Licata, David Gast
  • Patent number: 10239694
    Abstract: A warehouse automation system adapted to improve warehouse operating productivity includes a plurality of carts for transporting products within a warehouse and a controller. The controller is adapted to associate a first one of the plurality of carts with a first person and to control the first cart to lead the first person around the warehouse. According to one advantage, the time the first person spends restocking, picking, counting, sorting, moving, and packing product into customer orders and shipments, for example, is reduced.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: March 26, 2019
    Assignee: 6 River Systems, Inc.
    Inventors: Rylan Hamilton, Jerome Dubois, Christopher Cacioppo, Timothy Higgins, Josh Chaitin-Pollak
  • Patent number: 10163202
    Abstract: The present invention provides an automatic blood-sampling tube preparation device which can detect the presence of the proper or improper blood-sampling tube by selectively taking out a blood-sampling tube and transferring the blood-sampling tube to a label pasting position, printing information of the patient on a label, pasting the printed label on the blood-sampling tube positioned in the label pasting position, and collecting the label pasted blood-sampling tubes in the container for each patient. The device also includes photographing means for photographing an appearance of the blood-sampling tube taken out from the blood-sampling tube containing section and a control means arranged to have a threshold with respect to at least one characteristic information previously extracted from an appearance of a blood-sampling tube, to extract the characteristic information from the appearance image photographed to judge whether the blood-sampling tube corresponds to the instruction information from the doctor.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: December 25, 2018
    Assignee: TECHNO MEDICA CO., LTD.
    Inventors: Toshikazu Matsumoto, Yoshimi Hirasawa, Yasushi Nakano, Yusuke Wada, Ichiro Nakamura
  • Patent number: 10006927
    Abstract: A method of operating a laboratory automation system is presented. The laboratory automation system comprises a plurality of laboratory stations and a plurality of sample container carriers. The sample container carriers carry one or more sample containers. The sample containers comprise samples to be analyzed by the laboratory stations. The system also comprises a transport plane. The transport plane supports the sample container carriers. The system also comprises a drive. The drive moves the sample container carriers on the transport plane. The method comprises, during an initialization of the laboratory automation system, logically reserving at least one buffer area on the transport plane and, after the initialization of the laboratory automation system, buffering in the at least one buffer area sample container carriers carrying sample containers comprising samples waiting for a result of an analysis. Depending on the result of the analysis, the samples are further processed.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: June 26, 2018
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Achim Sinz, Namitha Mallikarjunaiah, Christoph Pedain
  • Patent number: 9970952
    Abstract: The present invention provides an efficient apparatus for extracting biologically active substances through a magnetic particle method, comprising a magnetic needle, a magnetic needle moving mechanism, a sleeve and a sleeve moving mechanism and a vibration mechanism, a bracket, a positioning mechanism; the vibration mechanism is capable of generating vibrations to enable the sleeve moving mechanism to make upward and downward vibrations; wherein the magnetic needle can vertically insert into and move out of the sleeve; the sleeve can vertically insert into and move out of a sample treatment area; and the vibration mechanism comprises a lever bar, a movable fulcrum and a rotary mechanism. The present invention further provides an instrument comprising the apparatus for extracting biologically active substances. The present invention further provides a method for extracting and purifying biologically active substances using the apparatus or the instrument for extracting biologically active substances.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: May 15, 2018
    Inventors: Xinzhi Liu, Zhifang Guo, Haifeng Zhao
  • Patent number: 9958469
    Abstract: An automated method of isolating and analyzing an analyte using a form-locking gripping mechanism. An analytical system comprising consumables and a handler, wherein the handler and consumable interact with a form-locking gripping mechanism are also included.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: May 1, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Renato Belz, Urs Knecht, Christian Thalmann, Veronika Trottmann
  • Patent number: 9903798
    Abstract: Specimen collection slides, methods of fabricating and methods of utilizing such specimen collection slides whereby each specimen collection slide includes a top rigid layer with an opening, a bottom rigid layer with an opening substantially the same size as the top layer opening, a middle rigid section having an opening larger than the openings in both the top and bottom layers, and a filtration media residing within the opening in the middle section. The top, bottom and middle are secured together to provide the resultant slide with thickness and rigidity that lends the slide to be utilized in automated handling processes and instruments. The middle section of the slide encases the filtration media and sandwiches it between the top and bottom layers so that the filtration media is protected from damage. Each slide may have its own unique identifier.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: February 27, 2018
    Inventor: Thomas W. Astle
  • Patent number: 9846169
    Abstract: An automated system and method for storing/retrieving vessel holders is presented. A first storage compartment comprises first storage sections. A first translating mechanism vertically translates one storage section to a loading level for loading holders into the first storage compartment and translates one storage section to a handing-in level for handing in holders to/from an analyzer. A second storage compartment comprises second storage sections. A second translating mechanism vertically translates one second storage sections to a handing-out level and translates one storage section to an unloading level for unloading holders from the second storage compartment. A first transport mechanism comprises a first conveyor for transporting holders from a first storage section at the handing-in level to a handing-over station. A second transport mechanism comprises a second conveyor for transporting holders from the handing-over station to a second storage section at the handing-out level.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: December 19, 2017
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Martin Burri, Andreas Eberhart, Akihiro Tanji
  • Patent number: 9829497
    Abstract: A sample analysis system includes a first measurement unit, a second measurement unit arranged to a downstream side of the first measurement unit, and an information processing section which obtains a measurement result of a sample. The information processing section determines, based on the measurement result of the sample measured by the first measurement unit, whether or not a retest of the sample by the first measurement unit is necessary. When the retest by the first measurement unit is necessary, the information processing section causes the sample container to be transported to a first sample supply position for the first measurement unit and causes the first measurement unit to perform measurement of the sample.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: November 28, 2017
    Inventors: Hiroo Tatsutani, Tomoyuki Asahara, Keisuke Kuwano
  • Patent number: 9772341
    Abstract: An automatic positioning apparatus can be used for sucking out the specimen even if the shapes of racks differ from each other is provided. The automatic positioning apparatus includes a shape-information obtaining apparatus which obtains the shape information of the rack including arrangement information of a specimen vessel, a position determining apparatus which transports racks to arrange the specimen vessel at a specimen-sucking position, and a control unit which controls the position determining apparatus to transport racks depending on shaped of the racks based on the shape information of racks. Further, the automatic positioning apparatus includes a vessel detecting apparatus which detects whether there is the specimen vessel held in the rack, and at the same time, determines a position of the specimen vessel on the transport path as an adjustment reference position.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: September 26, 2017
    Assignee: Beckman Coulter, Inc.
    Inventor: Mizuki Nakamura
  • Patent number: 9739793
    Abstract: An analysis apparatus includes a first analysis unit which collects samples by utilizing a first nozzle to analyze the sample, a second analysis unit which collects samples by utilizing a second nozzle to analyze the sample, and a transport apparatus which transports a plurality of sample vessels along a predetermined transport route. When a predetermined waiting state is provided such that the transport of the plurality of sample vessels is interrupted or stopped, then the sample collecting position is changed for at least one of the first and second nozzles, and the samples are collected from the plurality of sample vessels by means of the nozzle having the changed position. Accordingly, it is possible to enhance the efficiency of the analysis process performed by the analysis apparatus, while suppressing the transport apparatus from being large-sized and suppressing the structure from being complicated.
    Type: Grant
    Filed: January 31, 2010
    Date of Patent: August 22, 2017
    Assignee: ARKRAY, Inc.
    Inventors: Noriaki Furusato, Kousuke Kubo
  • Patent number: 9733161
    Abstract: First and second racks each has fixed positions to hold sample tubes. First and second drawers slide into and out of the case, and that support the first and second racks, respectively. A tube set unit is provided in an area close to the first rack in the case. A tube transfer unit removes sample tubes from the first and second racks in the case and a controller that controls a transfer operation of the tube transfer unit. The first rack is supported by the first drawer such that the first rack leaves a transit location in the case behind the first drawer in the direction of the first drawer movement into the case. The controller controls the tube transfer unit to remove at least one sample tube from the second rack and transfers the tube to the tube set unit via a path traversing the transit location.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: August 15, 2017
    Inventors: Takaaki Nagai, Daigo Fukuma, Mitsuo Yamasaki, Noriyuki Nakanishi, Syunsuke Yao, Tomonori Okazaki, Takahiro Saino
  • Patent number: 9669406
    Abstract: In one aspect, the invention provides a sample assembly to be used in a fluorescent measurement device. The sample assembly comprises a sample carrier, a sample holder that comprises at least one receptacle and a movable platform. The sample carrier is shaped in such a way that it can be secured into the receptacle by a suitable locking means. The sample holder is held in place on the movable platform through any suitable means, such as for example, a magnetic means. The movable platform is capable of moving in a linear trajectory, an arcuate trajectory and combinations thereof. The movement of the movable platform and hence, the entire sample assembly is effected by at least one stepper motor.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: June 6, 2017
    Assignee: Reametrix, Inc.
    Inventors: Bala S. Manian, Pramod Kummaya
  • Patent number: 9551646
    Abstract: An apparatus for environmental tests includes a chamber having formed therein a test space for disposing a sample, and a tray that is provided on the upper surface of the chamber and has an open upper surface. A front wall of the tray is configured by an operation unit where switches are provided. A rear wall of the tray is configured by a control unit housing a control substrate. A left wall and a right wall of the tray are configured by hollow bodies connecting the operation unit and the control unit. The tray is covered with a lid.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: January 24, 2017
    Assignee: ESPEC CORP.
    Inventors: Osamu Matsuguma, Tetsuya Shimada, Shuichi Kanazawa
  • Patent number: 9535083
    Abstract: In some embodiments of the invention, the central controller may comprise a processor and a computer readable medium coupled to the processor. The computer readable medium comprises code, executable by the processor to implement a method. The method comprises identifying, by the processor, a sample container or a sample container holder associated with the sample container, and then accessing, by the processor, a location database storing mapping data correlating sample containers or sample container holders with sample containers to test regions in the storage unit. The test regions store sample containers with samples that have been or are to be tested according to different tests. After accessing the database, the method continues by providing, by the processor, a proposal for storage of the sample container or the sample container holder associated with the sample container in the storage unit.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: January 3, 2017
    Assignee: Beckman Coulter, Inc.
    Inventor: Patrick Cohen
  • Patent number: 9505005
    Abstract: A tube sorter includes a rack stocker configured to have stocked therein a sample rack capable of holding one or more sample tubes. A transporting section is configured to transport the sample rack and a tube conveyor is configured to unload a sample tube from the sample rack and load the sample tube onto a sample rack supplied from or stocked in the rack stocker. A rack pushing mechanism is configured to convey an empty sample rack or a sample rack to be emptied to the rack stocker.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: November 29, 2016
    Inventor: Kei Takai
  • Patent number: 9500645
    Abstract: A microfluidic assay device that defines a micro-fluidic flow channel (44) having a flow axis, in which a series of discrete, axially-spaced apart, transparent hollow flow elements (32) are secured in fixed position, each flow element having at least one axially-extending flow passage through its interior, assay capture agent fixed to the interior surface of the elements for capture of an analyte in liquid flowing through the interior of the flow elements, the device constructed to enable light to be transmitted out of the elements for reading of fluorescence from captured analyte, wherein: the exterior axially-extending surfaces of the flow elements are free of active capture agent, while at least part of the interior surfaces carry deposits of active capture agent exposed to flow through the elements.
    Type: Grant
    Filed: September 6, 2014
    Date of Patent: November 22, 2016
    Assignee: CyVek, Inc.
    Inventors: Martin A. Putnam, Jeffrey T. Branciforte, Charles O. Stanwood, Jane M. Tu
  • Patent number: 9482662
    Abstract: The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may comprise immobilizing a plurality of analyte molecules or particles with respect to a plurality of capture objects. At least a portion of the plurality of capture objects may be spatially separated into a plurality of locations. A measure of the concentration of analyte molecules in a fluid sample may be determined, at least in part, on the number of reaction vessels comprising an analyte molecule immobilized with respect to a capture object. In some cases, the assay may additionally comprise steps including binding ligands, precursor labeling agents, and/or enzymatic components.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: November 1, 2016
    Assignee: Quanterix Corporation
    Inventors: David C. Duffy, David M. Rissin, David R. Walt, David Fournier, Cheuk Kan
  • Patent number: 9470608
    Abstract: This invention provides a sample processing system in which only one sample container is rested in one holder, the system being contemplated to prevent a mix-up of samples from occurring. A barcode labeler module 13 includes an identifier-reading device R1 that reads an identifier of a holder holding a primary-sample container, a printer 13B that prints a label based on information from a control PC unit 21 as well as on the identifier of the primary-sample container holder that has been read by the identifier-reading device R1, and affixes the label to a secondary-sample container, and a second identifier-reading device R2 that reads an identifier of the holder having the secondary-sample container mounted therein.
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: October 18, 2016
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kuniaki Onizawa, Hiroshi Ohga, Tatsuya Fukugaki
  • Patent number: 9417254
    Abstract: This analysis apparatus includes a plurality of a plurality of measurement units of mutually identical types generating measurement data by measuring the specimens, a transporter transporting the specimens to the respective ones of the plurality of measurement units, a display, common to the plurality of measurement units, displaying the analytical results generated by analyzing the measurement data and a transmitter transmitting the analytical results to a host computer.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: August 16, 2016
    Inventors: Takaaki Nagai, Masaharu Shibata, Yuichi Hamada, Daigo Fukuma
  • Patent number: 9395282
    Abstract: An isolator system includes first and second isolators respectively forming first and second workspaces hermetically sealed from ambient environment, and a pass box provided between the first and second isolators and forming a transport space enabled to communicate the first and second workspaces while maintaining hermeticity, wherein the pass box has a tray on which an article used in work is mounted, and a moving mechanism enabling movement of the tray toward directions to both sides of the first and second isolators, the tray has a first end on the first isolator side located in the first workspace when moved to the first isolator side, and a second end on the second isolator side located in the second workspace when moved to the second isolator side, and the first and second ends of the tray each has a grip bended downward from a mounting face of the tray.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: July 19, 2016
    Inventors: Koichi Kobayashi, Yasuhiko Yokoi
  • Patent number: 9395381
    Abstract: The invention relates to a rotatable device (1) for transporting reaction vessels in an automatic analysis apparatus, said device (1) comprising a circular base plate (16), and a number of holders (2) which are connected to the base plate (16), are preferably made of a plastic and comprise the receiving positions (4, 6) for the reaction vessels.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: July 19, 2016
    Inventors: Joachim Bernhard, Joerg Filzinger, Hugo Wilmes
  • Patent number: 9377479
    Abstract: A system and method for the automated processing of fluids according to a process operation plan involving the use of preloaded objects, which are to be present in target object positions, are disclosed. The system includes: a processing area in which objects to be used for the processing of fluids are located; at least one ultrasonic sensor for determining the presence of objects by acoustical waves; a positioning device to which the ultrasonic sensor is fixed and which moves the ultrasonic sensor in at least one direction relative to the processing area; a control computer determining the presence of objects and determining if objects are present in target object positions in the processing area as defined by the process operation plan; a pipetting device for pipetting of fluids between cavities located in the processing area; and an analytical or pre-analytical processing device for processing of fluids located in the processing area.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: June 28, 2016
    Assignee: Roche Molecular Systems, Inc.
    Inventor: Daniel Burkard
  • Patent number: 9372199
    Abstract: The sample analyzer includes: a reagent arranging section for arranging a plurality of reagents; an analyzing section for analyzing a measurement sample prepared by mixing a sample and the reagent arranged on the reagent arranging section; a display device; an input device; and a display control section for displaying a reagent arrangement displaying region for displaying a plurality of reagent marks inscribed with a reagent name respectively on the display device, wherein the each reagent mark is displayed in a manner selectable by the input device, wherein arrangement of the each reagent mark on the reagent arrangement displaying region corresponds to arrangement of the each reagent on the reagent arranging section, wherein the display control section displays detailed information related to the reagent corresponding to the reagent mark selected by the input device on the display device.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: June 21, 2016
    Assignee: Sysmex Corporation
    Inventors: Hiroyuki Fujino, Kyozo Fujita, Mitsuyo Ito
  • Patent number: 9366686
    Abstract: A microplate stacker capable of removing and replacing standard microplate lids by separating a microplate from a lid located directly above the microplate in a stack of microplates and lids.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: June 14, 2016
    Inventors: Matthew Stiles, William David Nicolay, G. Gerard Gormley, Byron Smith
  • Patent number: 9347586
    Abstract: The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides. The technology still more particularly relates to automated devices for carrying out pipetting operations, particularly on samples in parallel, consistent with sample preparation and delivery of PCR-ready nucleotide extracts to a cartridge wherein PCR is run.
    Type: Grant
    Filed: October 15, 2012
    Date of Patent: May 24, 2016
    Assignee: HandyLab, Inc.
    Inventors: Jeff Williams, Kerry Wilson
  • Patent number: 9333499
    Abstract: Pipetting apparatus has a block for holding pipette tips and connecting to pipette cones of a multiple-pipette head of a liquid handling apparatus. The block has cavities in an array and pipette tips inserted therein as well as conical plug-in openings for pipette cones of a multiple-pipette head. The block additionally has devices for connecting the block and the head. The block has receptacles with a shoulder and inserts for inserting into the receptacles, insert having a cavity, a cylindrical insertion opening with inserted pipette tip and a conical plug-in opening for sealing introduction of a pipette cone. Each insert has a support with which it rests on the shoulder of a corresponding receptacle when inserted into the block. Preferably each insert lies in the corresponding receptacle of the block with horizontal play on all sides.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: May 10, 2016
    Assignee: TECAN TRADING AG
    Inventor: Roland Bolliger
  • Patent number: 9329194
    Abstract: A laboratory automation system that is capable of carrying out clinical chemistry assays, immunoassays, amplification of nucleic acid assays, and any combination of the foregoing, said laboratory automation system employing at least one of micro-well plates and deep multi-well plates as reaction vessels. The use of micro-well plates as reaction vessels enables the laboratory automation system to assume a variety of arrangements, i.e., the laboratory automation system can comprise a variety of functional modules that can be arranged in various ways. In order to effectively carry out immunoassays by means of micro-well plates, a technique known as inverse magnetic particle processing can be used to transfer the product(s) of immunoassays from one micro-well of a micro-well plate to another.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: May 3, 2016
    Inventors: Patrick P. Fritchie, Gregory E. Gardner, Richard W. Mahoney
  • Patent number: 9322835
    Abstract: A biologic fluid sample analysis method and system is provided that includes a reagent depository, and analysis chamber, a biologic fluid transfer system, and a programmable analyzer. The reagent depository has a plurality of reagent deposits, and each reagent deposit located at a position within the depository independent of the other reagent deposits. The analysis chamber is adapted to quiescently hold a biologic fluid sample and one or more reagents during analysis. The biologic fluid transfer system has at least one fluid transfer device. The programmable analyzer is adapted to control the biologic fluid transfer system to acquire a volume of sample from a sample reservoir, dispense a volume of the sample into the reagent depository, acquire a volume of sample and reagent from the reagent depository, and to transfer the sample and reagent to the analysis chamber, and to analyze the combined sample and reagent.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: April 26, 2016
    Assignee: Abbott Point of Care, Inc.
    Inventor: Stephen C. Wardlaw
  • Patent number: 9304069
    Abstract: The invention relates to an apparatus for treatment of histological samples. The apparatus includes at least a working station, in which the sample gets into contact with a liquid reagent. Further, the apparatus includes a purification device, which blows off at least a part of the reagent adhering to the sample and/or the sample holding arrangement by means of a gas flow, or which sucks off at least a part of the reagent adhering to the sample and/or a sample holding arrangement.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: April 5, 2016
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Andrew Guy, Stella Knorr, Hermann Ulbrich
  • Patent number: 9297822
    Abstract: A laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly are disclosed. The laboratory system to handle laboratory sample tube racks includes a robotic arm (220) with a gripper (222) for gripping primary racks (PR), the primary racks (PR) to be handled include a first end surface (76) and a second end surface (78), the first end surface (76) having a first surface geometry and the second end surface (78) having a second surface geometry, and the gripper (222) includes a first gripping arm (226) and a second gripping arm (228), with the first gripping arm (226) having a gripping surface being complementary to the first surface geometry, and the second gripping arm (228) having a gripping surface being complementary to the second surface geometry.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: March 29, 2016
    Inventors: Rolf Frey, Fritz Goedl, Bruno Koch, Joachim Lackner, Ueli Stettler, Beat Widmer
  • Patent number: 9297797
    Abstract: A method of determining an electrolyte in a sample including adding the sample to an electrolyte module, the electrolyte module including a dilution cup, a flow cell, and a pump, the flow cell having a flow channel with a first end and a second end, the first end fluidically coupled to the dilution cup, and the second end fluidically coupled to the pump; combining the sample with a diluent in the dilution cup to produce a diluted sample; operating the pump to aspirate the diluted sample into the flow cell; measuring the electrolyte in the diluted sample in the flow cell; and reversing the pump to dispense fluid through the second end to displace the diluted sample from the flow cell back into the dilution cup.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: March 29, 2016
    Assignee: Beckman Coulter, Inc.
    Inventors: Richard Lou Situ, Youqin E. Xie, Yuan M. Xie
  • Patent number: 9291633
    Abstract: After being dispensed, a sample that needs to be quickly measured passes through another unit and is transported to an automatic analyzer. A plurality of units are provided for functions of processing including a dispensing unit that dispenses the sample stored in a sample vessel into another sample vessel. At least one discharge line discharges the sample from the dispensing unit to a transport line and a line that is perpendicular to the discharge line. A reverse direction transport line transports the sample in a direction reverse to a direction in which the sample loaded in the system is transported to the dispensing unit. The sample that is processed by the dispensing unit is transported to a storage unit located on the upstream side of the system, through the reverse direction transport line.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: March 22, 2016
    Inventors: Hiroshi Ohga, Tatsuya Fukugaki, Tetsuya Isobe, Shigeru Yano
  • Patent number: 9283557
    Abstract: A laboratory liquid handling system includes a pipetting module, a lab member, and a drive system. The pipetting module includes a pipettor including a pipettor shaft and a pipetting tip extending from an end of the pipettor shaft. The lab member includes a body and at least one adapter structure including an interlock feature configured to laterally receive and interlock with the pipettor shaft to releasably secure the lab member to the pipettor shaft. The drive system is operable to: selectively move the pipettor shaft laterally relative to the interlock structure to engage the pipettor shaft with the interlock structure to secure the lab member to the pipetting module; move the pipetting module to transport the lab member secured thereto; and selectively move the pipettor shaft laterally relative to the interlock structure to disengage the pipettor shaft from the interlock structure to thereby release the lab member.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: March 15, 2016
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Eugene S. Maslana, Karen A. McElroy, Dennis F. Malkowski, James W. Sim
  • Patent number: 9279819
    Abstract: A sample processing system is disclosed which includes at least one processor and at least one memory that stores programs executable collectively by the at least one processor. According to the stored programs, the at least one processor transports sample containers through a conveying path along which there are arranged at least one first module for testing of samples and at least one second module for processing of samples which have been tested by the at least one first module. The at least one second module is switchable between an active state and an inactive state. The at least one processor further obtains a determination result as to whether a sample which has been tested by the at least one first module is necessary to be processed by the at least one second module.
    Type: Grant
    Filed: August 30, 2010
    Date of Patent: March 8, 2016
    Inventors: Toru Mizumoto, Akio Toyoda
  • Patent number: 9269138
    Abstract: Methods for dispensing a fluid sample on a substrate include obtaining an image of a sample applicator in proximity to the substrate, where the image includes a first image of the sample applicator and a second image of the sample applicator, determining a height of the sample applicator relative to a surface plane of the substrate based on a distance between common portions of the first and second images, and dispensing the fluid sample onto the substrate using the sample applicator, where the dispensing includes: translating the sample applicator, translating the substrate, or translating both the sample applicator and the substrate to effect a relative translation between the sample applicator and the substrate; and maintaining the sample applicator within 2 microns of a target height relative to the surface plane of the substrate during the translating.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: February 23, 2016
    Assignee: Roche Diagnostics Hematology, Inc.
    Inventors: Russell Zahniser, David Zahniser, Stephen Conroy, Michael Zahniser
  • Patent number: 9259673
    Abstract: An assembly machine for assembling disposable syringe-driven filter is provided, which includes a rack and an automatic controller arranged on the rack. The automatic controller is electrically connected with a rotating table, a first automatic loading mechanism, an automatic filter disc-sucking mechanism, a second automatic loading mechanism, and an automatic unloading mechanism. Using the first and second automatic loading mechanisms, the automatic filter disc-sucking mechanism, and the automatic unloading mechanism, as well as the automatic controller, the assembly machine can realize the automatic loading of the upper cover of a disposable syringe-driven filter, the automatic placing of filter disc, the automatic loading and assembling of the lower cover of filter and the automatic unloading of the disposable syringe-driven filter, so that the automatic production of the disposable syringe-driven filter can be realized.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: February 16, 2016
    Inventors: Jianhua Yuan, Yejames Yuan