Waxes, Fatty Acids, Etc. (e.g., Liposome, Etc.) Patents (Class 424/420)
  • Patent number: 10369089
    Abstract: The presently disclosed subject matter relates to iron oxide nanoparticle compositions and formulations thereof for: (1) the treatment and elimination of biofilms; (2) the prevention of biofilm formation; (3) biofilm extracellular matrix degradation; (4) the inhibition of bacterial viability and growth within the biofilm; and (5) the prevention of tooth or apatitic demineralization. In particular, the presently disclosed subject matter provides a composition for the prevention and treatment of an oral disease (e.g., dental caries) that includes one or more iron oxide nanoparticles and hydrogen peroxide.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: August 6, 2019
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Hyun Koo, Lizeng Gao, David Cormode, Pratap Naha
  • Patent number: 9113627
    Abstract: Coating composition for an oilseed plant seed from which roots and shoots are capable of growing, wherein the coating composition comprises an organic carrier material and one or more biological agents that possess an activity against at least one or more pathogens of the oilseed plant.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: August 25, 2015
    Assignee: Exosect Limited
    Inventor: Nicholas Hugh Hylton Jessop
  • Patent number: 9012363
    Abstract: A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a second coating layer applied on the surface of the first coating layer. The first coating layer includes a wax composition having a biologically active ingredient incorporated therein and the second coating layer includes a polymeric composition. The granular agrochemical composition exhibits a controlled rate of release of the biologically active ingredient therefrom over a period greater than about 30 days from the date of initial exposure of the granular composition to moisture whereby essentially all of the biologically active ingredient incorporated in the wax material of the first coating layer is released from the granular composition before the water soluble portion of the granular core material is released from the granular composition.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: April 21, 2015
    Assignee: Everris International B.V.
    Inventors: Lonneke Jacoba van Boxtel-Verhoeven, Johannes Gijsbertus Antonius Terlingen, Petra Leonarda Hendrica Lunde-Vannuys
  • Patent number: 8936803
    Abstract: The present disclosure provides compositions comprising fatty acids, or derivatives thereof (e.g., C1-C4 esters) including, for example, DGLA, and/or 15-HETrE, used singly or in combination for the prevention and/or treatment of effects associated with UV radiation such as erythema.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: January 20, 2015
    Assignee: Dignity Sciences Limited
    Inventors: Mehar Manku, John Climax, David Coughlan
  • Patent number: 8911757
    Abstract: The present invention provides an insect or arthropod pesticidal composition. The composition includes active ingredients having a mixture of fatty acids, each of the fatty acids having a straight carbon chain from 6 to 12 carbon atoms long. The fatty acid mixture includes a first fatty acid molecule having a straight carbon chain from 6 to 8 carbon atoms long, and a carboxylic acid group. The fatty acid mixture also includes a second fatty acid molecule having a straight carbon chain from 8 to 12 carbon atoms long, and a carboxylic acid group. The composition also includes a carrier that promotes adherence or absorption or transport across the surface of insects or arthropods to effect their incapacitation or death.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: December 16, 2014
    Assignee: Stratacor, Inc.
    Inventor: William Reifenrath
  • Patent number: 8815298
    Abstract: A therapeutic composition is described comprising honey or a honey derivative, a surfactant, and at least one topical carrier or vehicle selected from the group consisting of a fatty ester, a wax and a wax-like compound; wherein the composition has been subjected to a sterilization effective dosage of radiation, and wherein the topical carrier or vehicle, when subjected to that dosage, does not substantially modify the properties of the composition present before the sterilization.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: August 26, 2014
    Assignee: Medihoney Pty Ltd
    Inventor: Anthony Peter Moloney
  • Patent number: 8795697
    Abstract: The invention provides a sanitizing composition in the form of a viscous liquid or gel suitable for use as a handwash composition comprising alcohol, water and a thickener wherein the viscous liquid or gel has particles suspended therein, wherein said particles provide the composition with a granular texture and are capable of being worn away when rubbed. The particles may deliver one or more agents to the skin e.g. antimicrobial, antibacterial or antiviral agents, emollients and/or moisturizers, fragrances, colorings or UV markers.
    Type: Grant
    Filed: April 9, 2005
    Date of Patent: August 5, 2014
    Inventor: James S. Brown
  • Patent number: 8709460
    Abstract: A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione salt particles with a de-agglomerating agent to produce the desired de-agglomerated pyrithione salt particles. Also disclosed is a method for making de-agglomerated submicron-sized particles of pyrithione salts comprising a heating step. Also disclosed are the particles made by the above methods and compositions comprising the particles and a base medium.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: April 29, 2014
    Assignee: Arch Chemicals, Inc.
    Inventors: Saeed M. Mohseni, Charles W. Kaufman, David C. Beaty, John J. Jardas, George Polson
  • Patent number: 8685425
    Abstract: Microcapsules possessing Lewis acid-Lewis base salt walls incorporate water-immiscible materials, such as N,N-di-ethyl-m-toluamide (DEET), as a core component. Such microcapsules, or similar microcapsules incorporating other core components, may be made by emulsifying a water-immiscible core component in an aqueous solution of one wall-forming reactant, such as the Lewis base, and then mixing that solution with the other wall-forming reactant, such as the Lewis acid. Various adjuvants may be included with the core component to contribute additional characteristics, such as enhancement of a controlled release characteristic or improved mechanical stability.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: April 1, 2014
    Inventor: Tycho J. Speaker
  • Patent number: 8663671
    Abstract: Methods and compositions for producing hydrogel capsules enveloped with at least one coating layer is disclosed. The coating formulations deposited on the surface of the capsules can improve the physical integrity and the water-retention properties of the alginate beads. The coating formulations can be sequentially applied in various combinations to obtain desirable properties, such as improved physical integrity, mechanical strength, and low permeability, that can extend the shelf-life of the capsules when incorporated into various consumer products.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: March 4, 2014
    Assignee: Philip Morris USA Inc.
    Inventors: Georgios D. Karles, Daqing Wu, Shuzhong Zhuang
  • Patent number: 8647631
    Abstract: The present invention is related to methods and pharmaceutical compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to pharmaceutical composition comprising an antigenic peptide, particularly an antigenic phospho-peptide mimicking a major pathological phospho-epitope of protein tau, for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: February 11, 2014
    Assignees: Katholieke Universiteit Leuven, AC Immune S.A.
    Inventors: Andrea Pfeifer, Andreas Muhs, Fred Van Leuven, Maria Pihlgren
  • Publication number: 20140030306
    Abstract: A method for remediating bacterially-induced corrosion, environmental damage, and/or process inefficiencies in an industrial process includes identifying an industrial process where target bacteria adversely affect corrosion, environmental impact, and/or process efficiencies. The process also includes identifying the strains of the target bacteria, obtaining a bacteriophage virulent against one or more of the strains of the target bacteria, and exposing the target bacteria to the bacteriophage. The method can utilize an aqueous composition comprising bacteriophage encapsulated in at least one selected from the group consisting of: liposomes, foam, and gel.
    Type: Application
    Filed: March 29, 2012
    Publication date: January 30, 2014
    Applicant: General Electric Company
    Inventors: David Matthew Polizzotti, Cato Russell McDaniel, Claudia C. Pierce, Stephen Robert Vasconcellos
  • Patent number: 8603487
    Abstract: The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis. In particular, the present invention provides novel methods and compositions for eliciting a highly specific and highly effective immune response in an organism, but particularly within an animal, particularly a mammal or a human, which is capable of preventing or alleviating amyloidosis, or the symptoms associated with amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD), including diseases or conditions characterized by a loss of cognitive memory capacity such as, for example, mild cognitive impairment (MCI).
    Type: Grant
    Filed: April 14, 2009
    Date of Patent: December 10, 2013
    Assignee: AC Immune S.A.
    Inventors: Andrea Pfeifer, Claude Nicolau
  • Patent number: 8568759
    Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 29, 2013
    Assignee: W. Neudorff GmbH KG
    Inventor: Diana L. Parker
  • Patent number: 8557229
    Abstract: A method of removing hair from skin, preferably facial skin, is provided, comprising the steps of: (a) applying a hydrophobic protective composition to an area of skin, preferably facial skin, on which unwanted hair is growing, the hydrophobic protective composition being capable of reducing the penetration of thioglycolic acid by at least 45%, as measured using the Franz Cell Method; (b) applying a depilatory composition to the area of skin to which the hydrophobic protective composition has been applied, the depilatory composition comprising a keratin reducing agent.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: October 15, 2013
    Assignee: The Procter & Gamble Company
    Inventors: Charles Robert Smith, Stuart Andrew Hewlins, Michael John Goffe, Paul Jonathan Matts, Paul James Smith
  • Publication number: 20130224275
    Abstract: A method of delivering a biologically active chemical agent to an arthropod pest of a bee, comprising exposing a surface of the said bee to carnauba wax particles having a volume mean diameter of at least 10 ?m comprising at least one biologically active chemical agent, wherein the bee delivers the biologically active chemical agent to the arthropod pest, characterized in that the carnauba wax particles consist essentially of 89.5-99.4% by weight of carnauba wax; ?10% by weight of biologically active chemical agent; and 0.5% by weight of flow agent.
    Type: Application
    Filed: August 11, 2011
    Publication date: August 29, 2013
    Applicant: EXOSECT LIMITED
    Inventors: Clare Gillian Storm, Nicola Jane Huggett
  • Patent number: 8497229
    Abstract: A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a second coating layer applied on the surface of the first coating layer. The first coating layer includes a wax composition having a biologically active ingredient incorporated therein and the second coating layer includes a polymeric composition. The granular agrochemical composition exhibits a controlled rate of release of the biologically active ingredient therefrom over a period greater than about 30 days from the date of initial exposure of the granular composition to moisture whereby essentially all of the biologically active ingredient incorporated in the wax material of the first coating layer is released from the granular composition before the water soluble portion of the granular core material is released from the granular composition.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: July 30, 2013
    Assignee: Everris International B.V.
    Inventors: Lonneke Jacoba van Boxtel-Verhoeven, Johannes Gijsbertus Antonius Terlingen, Petra Leonarda Hendrica Lunde-Vannuys
  • Patent number: 8383138
    Abstract: A method of repelling sharks for limiting their attacking a surfboard user comprises applying a conventional surfboard traction improving solid wax that also incorporates a shark repellent such as a surfactant, a capsaicinoid or a semiochemical in a concentration based on the “Johnson & Baldridge Test”. The extent of application is consequently sufficient to render the coated surfboard foul tasting when bitten by a shark but insufficient to reliably repel a shark in response to the dispersion in the water of the repellent. The invention extends to a shark repellent incorporating surfboard coating wax.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: February 26, 2013
    Inventor: Anthony Neville Drew
  • Patent number: 8226968
    Abstract: The invention relates to a liposomal composition, containing a citrus type (Aurantioideae) essential oil of pharmaceutical grade 0.5-5.0 part by weight; lavender oil of pharmaceutical grade 0.5-5.0 part by weight; vitamin E 0.1-1.5 part by weight; vitamin A 0.1-1.5 part by weight; castor oil ethoxylated 1.0-6.0 part by weight; a phospholipid 0.1-1.0 part by weight; distilled water 15-30 part by weight; ethanol 96% 65-75 part by weight. The composition can be used for treatment of wounded, burned, frozen, infected skin surfaces.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: July 24, 2012
    Assignee: Invencio-21 Gyogyhatasu Keszimenyeket Gyarto KFT
    Inventors: József Gaál, Laszlone Kollárik, András Szego
  • Publication number: 20120128747
    Abstract: The present invention relates to a material in the form of solid particles consisting of a continuous shell including at least one silicon oxide, said shell confining at least one oil phase, said material being characterized in that said oil phase is solid at the storage temperature of said material and predominately contains a crystallizable oil that has a melting temperature (TM) of less than 100° C. and at least one substance of interest, and in that the diameter of the particles varies from 1 ?m to 1 cm. The invention also relates to a method for preparing said material, to the use thereof for the thermostimulated generation of active substances, as well as to compositions containing same.
    Type: Application
    Filed: July 28, 2010
    Publication date: May 24, 2012
    Inventors: Schmitt Véronique, Mathieu Destribats, Rénal Backov
  • Publication number: 20120114728
    Abstract: A biodelivery system has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex biofilm matrices through the use of liposome carriers, thereby removing the biofouling in industrial water bearing systems, including piping, heat exchanges, condensers, filtration systems and fluid storage tanks. According to one embodiment of the invention, antimicrobial compound containing liposomes are added to water systems prone to biofouling and biofilm formation. The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the existing biofilm. Once the antimicrobial compound containing liposomes become entrained with the biofilm matrix, the decomposition or disintegration of the liposome proceeds. Thereafter the biocidal core is released to react directly with the biofilm encased microorganisms.
    Type: Application
    Filed: February 12, 2010
    Publication date: May 10, 2012
    Inventors: Wilson Kurt Whitekettle, Gloria Jean Tafel, Kimberly Murphy, Qing Zhao
  • Patent number: 8158158
    Abstract: A biocidal composition is disclosed comprising composite particles, each of said composite particles containing a shell and a core, said core comprising a metal or a metal-containing compound wherein the metal is a moiety selected from the group consisting of zinc, copper, bismuth, silver, zirconium, and combinations thereof said shell comprising a pyrithione adduct comprising the reaction product of pyrithione with a portion of said core metal or metal compound. In one aspect, an anti-fouling composition is disclosed comprising (a) an anti-soft-fouling effective amount of copper pyrithione; and (b) an anti-hard-fouling effective amount of a copper-containing salt, or oxide or hydroxide thereof. The present invention also relates to a method of making an anti-fouling composition comprising particles of copper pyrithione and a copper-containing salt that is effective against hard-fouling and soft-fouling organisms.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: April 17, 2012
    Assignee: Arch Chemicals, Inc.
    Inventors: David F. Gavin, Craig Waldron, Robert J. Martin, George A. Polson
  • Patent number: 8088747
    Abstract: The invention relates to a compound of general formula (I): where X=0 or 1, Z=O, S or CH2, R1 and R2 independently=OH or OY, where Y=a protecting group, OR3, where R3=a monosaccharide or disaccharide group, A1-CH2—N+(CH3)3, X?, where X=halogen, A1=an amide (NHC(O)) or ester (OC(C)) bond, OPO(OM)2, where M=an alkyli or alkyli earth metal, OP(O)O?—O(CH2)2—N+(CH3)3, A2-(PEGX1-A3)n-R4, where n=0 or 1, PEGX1=a polyethyleneglycol of molecular weight X1, where X1 being less than or equal to 5,000 daltons, A2 and A3 independently=a ether (O), ester (OC(O)), amide (NHC(O)), urea (NHC(O)NH), thiourea (NHC(S)NH), or thioether (S) bond R4=a directing agent.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: January 3, 2012
    Assignees: Ecole Nationale Superieure de Chime de Rennes, Universite de Bretagne Occidentale
    Inventors: Thierry Benvegnu, Daniel Plusquellec, Gildas Rethore, Mickaelle Scahet, Claude Ferec, Tristan Montier, Pascal Delepine, Pierre Lehn
  • Patent number: 8067018
    Abstract: A microcapsule comprising a core material containing pyrethrin and a capsule shell wall which surrounds said core material, said shell wall material comprises gelatin and at least one polysaccharide selected from the group consisting of gum arabic and pectin is effective for controlling insects.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: November 29, 2011
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Yosuke Baba, Hidenori Eguchi
  • Patent number: 8039015
    Abstract: Microcapsules possessing Lewis acid-Lewis base salt walls incorporate water-immiscible materials, such as N,N-diethyl-m-toluamide (DEET), as a core component. Such microcapsules, or similar microcapsules incorporating other core components, may be made by emulsifying a water-immiscible core component in an aqueous solution of one wall-forming reactant, such as the Lewis base, and then mixing that solution with the other wall-forming reactant, such as the Lewis acid. Various adjuvants may be included with the core component to contribute additional characteristics, such as enhancement of a controlled release characteristic or improved mechanical stability.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: October 18, 2011
    Inventor: Tycho J. Speaker
  • Patent number: 7931910
    Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: April 26, 2011
    Assignee: W. Neudorff GmbH KG
    Inventor: Diana L. Parker
  • Publication number: 20110052655
    Abstract: A method for controlling protozoa trophozoites and cysts wherein one or more biocides or non-biocidal agents are encapsulated within a micro-capsule or nano-capsule and then introduced into an aqueous system. The micro-capsule or nano-capsule has an exterior composition adapted for digestion by the protozoa. A vesicle for controlling protozoa trophozoites and cysts is also provided.
    Type: Application
    Filed: July 26, 2010
    Publication date: March 3, 2011
    Inventors: Wilson Kurt WHITEKETTLE, Gloria Jean Tafel, Dorothy G. Reynolds, Paul Robert Frail, Linna Wang, Juan Jiang, Qing Zhao
  • Patent number: 7887828
    Abstract: The present invention discloses systems and methods for controlling arthropod populations. The systems include a polymeric substrate, a semiochemical that is reactive upon an adult-stage arthropod, and an insecticide that is toxic to an immature-stage arthropod. The semiochemical may be a sex pheromone that disrupts mating behavior of the adult-stage arthropod. The insecticide may be a per os insecticide that only affects the immature-stage arthropod. The arthropod to be controlled may be gypsy moths, in which case the semiochemical may be disparlure and the insecticide may be spinosad. Further disclosed are methods for preparing systems for use in controlling arthropod populations.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: February 15, 2011
    Assignee: ISCA Technologies, Inc.
    Inventor: Agenor Mafra-Neto
  • Patent number: 7807175
    Abstract: The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis. In particular, the present invention provides novel methods and compositions for eliciting a highly specific and highly effective immune response in an organism, but particularly within an animal, particularly a mammal or a human, which is capable of preventing or alleviating amyloidosis, or the symptoms associated with amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD), including diseases or conditions characterized by a loss of cognitive memory capacity such as, for example, mild cognitive impairment (MCI).
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: October 5, 2010
    Assignee: AC Immune SA
    Inventors: Andrea Pfeifer, Claude Nicolau
  • Publication number: 20100239630
    Abstract: A biodelivery system has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex biofilm matrices through the use of liposome carriers, thereby removing the biofouling in industrial water bearing systems, including piping, heat exchanges, condensers, filtration systems and fluid storage tanks. According to one embodiment of the invention, antimicrobial containing liposomes are added to water systems prone to biofouling and biofilm formation. The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the existing biofilm. Once the antimicrobial compound containing liposomes become entrained within the biofilm matrix, the decomposition or disintegration of the liposome proceeds. Thereafter the biocidal core is released to react directly with the biofilm encased microorganisms.
    Type: Application
    Filed: March 20, 2009
    Publication date: September 23, 2010
    Inventors: Wilson Kurt Whitekettle, Gloria Jean Tafel
  • Publication number: 20100233224
    Abstract: Biocide-filled liposome vesicles containing one or more photosensitizers are located in one or more areas for potential sterilization. Upon receiving one or more signals, the liposome vesicles are irradiated with light causing the membrane of the vesicles to break, thereby releasing the biocidal agent or agents which are distributed throughout the area. Preferred biocidal agents are hydrogen peroxide, benzalkonium chloride, and photo-oxidizing nanoparticles such as titanium dioxide, iron oxide, and certain commercially available biocides such as Ucarcide 25 and Ucarcide 50 from Dow Chemical Co. In an alternative embodiment, upon receiving a signal, the liposome vesicles are distributed throughout the area and then irradiated with light.
    Type: Application
    Filed: February 23, 2009
    Publication date: September 16, 2010
    Applicant: EPIR TECHNOLOGIES, INC.
    Inventors: Dinakar RAMADURAI, William Christopher OROSZ, James W. GARLAND
  • Patent number: 7758893
    Abstract: The present invention relates to an enteral composition containing phospholipids, triglycerides and cholesterol or precursors thereof, which can be used in the treatment of sepsis. With the composition of the invention the natural level of chylomicrons is maintained, in particular in gut associated lymphoid tissue (GALT), which ensures that most of LPS and/or LTA which are released in the body can be neutralized, substantially decreasing the risk of locally occurring high levels of LPS and/or LTA and thus sepsis.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: July 20, 2010
    Assignee: N.V. Nutricia
    Inventors: Robert Johan Joseph Hageman, Gelske Speelmans, Adrianus Johannes Maria Vriesema
  • Patent number: 7658939
    Abstract: Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is administered intact.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: February 9, 2010
    Assignee: Purdue Pharma L.P.
    Inventors: Benjamin Oshlack, Curtis Wright, J. David Haddox
  • Patent number: 7651694
    Abstract: The present invention provides calcium phosphate nano-particles encapsulated with biologically active macromolecules. The particles may be used as carriers of biologically active macromolecule for delivery of the macromolecules. The invention also provides methods of making and using the particles.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: January 26, 2010
    Assignee: NOD Pharmaceuticals, Inc.
    Inventor: William W. Lee
  • Patent number: 7635675
    Abstract: Fatty acid salt particles having a size distribution wherein the particles are from about 1 to about 1,000 microns in diameter, use of the particles in pharmaceutical compositions, as well as methods of making and using the particles and compositions.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: December 22, 2009
    Assignee: Biocon Limited
    Inventors: Foyeke Opawale, Richard Soltero
  • Patent number: 7615539
    Abstract: The invention relates to a nucleic acid-lipophilic conjugates and methods for modulating an immune response using the conjugates. The lipophilic moiety associated with an immunostimulatory nucleic acid.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: November 10, 2009
    Assignees: Coley Pharmaceutical Group, Inc., Coley Pharmaceutical GmbH
    Inventors: Eugen Uhlmann, Jörg Vollmer, Arthur M. Krieg
  • Patent number: 7531187
    Abstract: A synergistic insecticidal composition is formed containing a Chloronicotynyle compound and a Pyrethroids compound. The Chloronicotynyle compound is provided in an amount preferably ranging from 0.1 to 5.0% by weight of the synergistic insecticidal composition. The Pyrethroids compound is provided in an amount preferably ranging from 1 to 60% by weight of the synergistic insecticidal composition. The synergistic insecticidal composition also preferably includes 35 to 98.90% by weight of conventional agriculturally acceptable carrier(s) and/or excipients.
    Type: Grant
    Filed: July 13, 2004
    Date of Patent: May 12, 2009
    Assignee: United Phosphorus, Ltd.
    Inventors: Prakash Mahadev Jadhav, Jaidev Rajnikant Shroff
  • Patent number: 7498028
    Abstract: The invention relates to surfactant-free reagent spheres useful for biological tests particularly those involving antigen/antibody reactions.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: March 3, 2009
    Inventors: Susan Goertz, Paul Hemmes
  • Patent number: 7445791
    Abstract: A synergistic insecticidal composition is prepared by combining a Chloronicotynyle compound and an Organophosphorus (OP) compound. The preferred synergistically effective amount of the Chloronicotynyle compounds is an amount preferably ranging from 0.1 to 5% by weight of the composition. The preferred synergistically effective amount of the Organophosphorus (OP) compounds is an amount preferably ranging from 30 to 75% by weight of the composition. The composition also preferably includes 69.9 to 20% by weight of conventional agriculturally acceptable carrier(s) and/or excipient.
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: November 4, 2008
    Assignee: United Phosphorus, Ltd.
    Inventors: Prakash Mahadev Jadhav, Jaidev Rajnikant Shroff
  • Publication number: 20080213329
    Abstract: A method of delivering a biologically active agent to a target site comprising exposing a surface of a non-target carrier organism to a carrier comprising at least one biologically active agent, wherein the non-target carrier organism delivers the biologically active agent to the target site.
    Type: Application
    Filed: May 10, 2006
    Publication date: September 4, 2008
    Applicant: EXOSECT LIMITED
    Inventor: Ian Hamilton Baxter
  • Patent number: 7393521
    Abstract: Composition and method for promoting growth of microbes that are capable of degrading animal waste. The method includes applying a nontoxic composition to a bedding substrate that is disposed to receive animal waste. The composition comprises a carboxylic acid, preferably the carboxylic acid is a fatty acid, and more preferably a combination of a saturated fatty acid and an unsaturated fatty acids. Specifically, a preferred composition comprises a saturated fatty acid having from 12 to 22 carbon atoms and an unsaturated fatty acid having from 12 to 22 carbon atoms. A still more preferred composition used both saturated and unsaturated fatty acids having from 16 to 20 carbon atoms. Optionally, the composition may include or encapsulate nutrients, an oxygen-releasing compound, or microbes.
    Type: Grant
    Filed: February 18, 2004
    Date of Patent: July 1, 2008
    Assignee: Bionutratech, Inc.
    Inventor: Sandra Hruza
  • Patent number: 7393541
    Abstract: Compositions and methods for enhancing the immunity of a subject or vaccinating a subject against mycobacterial infections are disclosed. The invention provides compositions comprising formalin inactivated cultures of a mycobacterium, such as M. bovis, and a Novasome® adjuvant, as well as methods for using such compositions.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: July 1, 2008
    Assignee: Novavax, Inc.
    Inventors: D. Craig Wright, Joan Brisker, Mark A. Chambers
  • Patent number: 7344730
    Abstract: The present invention relates to soil-applied CR granules obtainable by applying an active-ingredient-comprising coating to a solid carrier in a fluidized bed, to a process for the preparation of these soil-applied granules, and to a method for controlling phytopathogenic fungi, undesired vegetation, undesired attack by insects and/or for regulating the growth of plants using the soil-applied CR granules according to the invention.
    Type: Grant
    Filed: July 28, 1999
    Date of Patent: March 18, 2008
    Assignee: BASF SE
    Inventors: Reinhold Stadler, Reiner Kober, Karl-Heinrich Schneider, Reinhold Saur, Herbert Bayer, Karl Kolter, Michael Seufert
  • Patent number: 7341739
    Abstract: The small particle liposome aerosol compounds and methods of treatment of the present invention involve lipid- or water soluble anti-cancer drugs incorporated into liposomes. The liposomes are administered in aqueous dispersions from a jet nebulizer to the respiratory tract of an individual. Various anti-cancer drugs may be used, including 20-S-Camptothecin, 9-Nitro-camptothecin, 9-Amino-camptothecin, 10, 11-methylenedioxy-camptothecin and taxol or its derivatives. Administration of these drugs by inhalation provides faster and more efficient absorption of the anticancer drug than does intramuscular administration or oral administration.
    Type: Grant
    Filed: May 11, 2004
    Date of Patent: March 11, 2008
    Assignee: Research Development Foundation
    Inventors: Beppino C. Giovanella, J. Vernon Knight, J. Clifford Waldrep, Nadezhda Koshkina, Brian Gilbert, Clyde W. Wellen
  • Patent number: 7163687
    Abstract: The present invention provides a shelf-life extending pesticide formulation, and methods of making and methods of use. The present invention prolongs the shelf-life many fold. In addition, methods of controlling insects on cattle are also provided.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: January 16, 2007
    Assignee: Wellmark International
    Inventors: Dennis Lee Murphy, Jeanne Ann Witte, Kim W. Yang
  • Patent number: 7070795
    Abstract: One or more agricultural active ingredients (such as fungicides or insecticides) are entrapped in polymeric matrixes to form particles having a diameter in the range from about 0.2 to about 200 microns. The particles are applied to soil, to seeds, or to plants and release the active ingredient(s) at a rate sufficiently low to avoid phytoxicity but at a rate sufficiently high to provide effective amounts of the active ingredient(s), preferably throughout the growing period of the plant.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: July 4, 2006
    Assignee: Monsanto Company
    Inventors: M. Francis Botts, Frank C. Kohn, Maria L. Miller
  • Patent number: 7067133
    Abstract: The present invention generally relates to the detection, treatment or prevention of disease states. Specifically, the present invention relates to the detection, treatment or prevention of amyloidosis or amyloid-associated diseases. The present invention further comprises methods and compositions comprising therapeutic vaccines, antisera and molecular constructs, comprising expression vectors and fusion proteins encoded therein.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: June 27, 2006
    Assignees: Aventis Pharma S.A., Université Louis Pasteur
    Inventor: Yves Claude Nicolau
  • Patent number: 7056522
    Abstract: A method for applying a barrier to structures to prevent the infiltration of pest species (unwanted organisms) uses a (e.g., coating) composition formed from a polyurethane (e.g., film-forming) polymer system and a pellet comprising a pesticide incorporated into a sorbent and dispersed in the polyurethane polymer system. The composition protects the structure by application either to the structure or to a pathway that leads to the structure. Advantageous polymer systems include polyurethanes rich in urea linkages and predominating in aliphatic and alicyclic backbones.
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: June 6, 2006
    Assignee: Termiguard Technologies, Inc.
    Inventors: Peter Van Voris, Dominic A. Cataldo, Edward S. Lipinsky
  • Patent number: 7045138
    Abstract: A composition including a bait and a borate is used to mitigate a population of target insects and/or mollusca. The composition may include attractive by-products of agriculture and manufacturing with or without semiochemicals or biopesticides prepared as point source units (such as pellets or microcapsules). The by-products attract insects and/or mollusca to a food source for the purpose of mitigating the target organism. The bait is combined with borates and is pelletized and/or encapsulated into micron size particles. The pelletized and/or encapsulated particles are broadcast (spread) over areas infested with the target insect. The insects ingest the composition and regurgitate the composition to the remainder of the insect population. Significant mitigation of the population of the target insects results with little to no effect on the environment. The composition is also passed on to the next generation due to cannibalism of the target insects.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: May 16, 2006
    Assignee: American Natural Technology Sciences, Inc.
    Inventors: John Wayne Kennedy, Patrick Kennedy
  • Patent number: 7037515
    Abstract: There is provided a topical composition that comprises (a) a substantially anhydrous insect repellent selected from the group consisting of ethyl 3-(N-butylacetylamino) propionate or a derivative thereof, p-menthane-3,8-diol, hydroxyethyl isobutyl piperidine carboxylate (1-piperidine carboxylic acid), and mixtures thereof, and (b) a non-volatile solvent. A second embodiment of the present composition includes the same insect repellent, and a volatile solvent, and, optionally, a film former. A third embodiment includes the same insect repellent, a non-volatile solvent, a volatile solvent, and, optionally, a film former.
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: May 2, 2006
    Assignee: Avon Products Inc.
    Inventors: Robert E. Kalafsky, Andrew H. Pechko, Mark Garrison