Web, Sheet Or Filament Bases; Compositions Of Bandages; Or Dressings With Incorporated Medicaments Patents (Class 424/443)
  • Patent number: 11459699
    Abstract: An antibacterial leather uses the organic silica gel as the main component, uses the carboxymethyl chitosan silver as the antibacterial factor, and uses the modified nano-silica and the modified layered double oxide as the flame retardant factor. The synergistic effects between the components, such as the good binding between carboxymethyl chitosan silver and the substrate, the synergistic flame retardant effect between flame retardant factors, the bonding effect between modified nano-silica and dimethicone, and the synergistic effect between the high-viscosity dimethicone and the low-viscosity dimethicone are utilized to improve the process, thereby obtaining a good antibacterial, flame retardant and other properties, meanwhile meeting the requirement for the material mechanical properties and environmental protection.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: October 4, 2022
    Assignee: XIAMEN XIN DE LI INVESTMENT & DEVELOPMENT CO., LTD.
    Inventors: Liguo Yang, Ziqiao Liu, Siyong Chen
  • Patent number: 11441261
    Abstract: The invention provides fabrics that incorporate protease enzymes that inactivate viruses and bacteria. The fabrics of the invention may be used in the production of various items of self-sterilizing protective equipment including protective facemasks.
    Type: Grant
    Filed: September 6, 2021
    Date of Patent: September 13, 2022
    Assignee: WABESO Enhanced Enzymatics, Inc.
    Inventor: Mandy Jane Ward
  • Patent number: 11426442
    Abstract: Compositions and methods for skincare treatment are provided. The invention relates more generally to skin care treatment and more particularly, to compositions and methods for promoting healthy skin, skin regeneration, skin repair, skin bed preparation, and enhanced wound healing.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: August 30, 2022
    Assignee: ALASTIN SKINCARE, INC.
    Inventors: John A. Garruto, Alan David Widgerow
  • Patent number: 11414574
    Abstract: A compostable biopolymer adhesive may include a starch, a hydroxylic liquid, a preservative mixture, a crystallization inhibitor, and a carbonate, wherein the compostable biopolymer may be free of synthetic materials yet has a long shelf life, is stable at room temperature, and which can be used to make slime for play. The preservative mixture may include a mixture of saccharides and salt, and the salt may make up about 10 to about 90 wt. % of the dry materials used to make the compostable biopolymer adhesive.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: August 16, 2022
    Inventor: Ana Maria Visinoni-Davidov
  • Patent number: 11406607
    Abstract: Compositions for treatment of cystinosis, products for administering eye drops, and products for storing contact lenses are provided. Compositions include solutions that can contain an effective amount of cysteamine to treat cystinosis, and an oil with a lower density than the solution. Also provided is a product including a bottle for containing a solution, the bottle being substantially free of O2. Also provided is a contact lens holder for storing one or more contact lenses in a solution, the holder including barrier layers reducing the amount of O2 entering the contact lens holder.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: August 9, 2022
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Anuj Chauhan, Phillip J. Dixon
  • Patent number: 11406945
    Abstract: A device or system includes a mixer comprising a three-dimensional lattice defining a plurality of tortuous, interconnecting passages therethrough. The mixer is in communication with sources or streams of at least two separate components which, when mixed, form a combined fluid stream. The sources or streams may be, at least initially, on opposite sides of the mixer, or the sources or streams may be on the upstream side of the mixer with an outlet disposed downstream of the mixer. A related method may include providing a mixer comprising a three-dimensional lattice defining a plurality of tortuous, interconnecting passages therethrough, and selecting a material for the mixer based on physical characteristics of said material, said characteristics including a selected one or more of mean flow pore size, thickness and porosity volume.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: August 9, 2022
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventor: Yves A. Delmotte
  • Patent number: 11396148
    Abstract: A method for making an improved contact lens with the steps of providing a mold with a space between the top surface and a bottom surface, and positioning a mat in the space of the mold, providing a bead of liquid polymer of predetermined size at a predetermined location on the surface of the mat, pressing the bead of liquid polymer into the mat between the top surface and the bottom surface of the mold to form an optical zone framed by a mat peripheral zone, exposing the optical zone and the peripheral zone with U-V radiation to harden the optical zone into a composite improved contact lens, removing the cross-linked improved contact lens from the mold, processing the peripheral zone surrounding the optical zone to have a fenestration surface having holes, the holes being through holes with predetermined diameters selected to pass larger proteins, lipids, metabolites.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: July 26, 2022
    Inventor: Randall F. Fuerst
  • Patent number: 11389319
    Abstract: An ostomy barrier includes an inlet opening for receiving a stoma and a barrier adhesive including a plurality of thicker portions and a plurality of thinner portions. The plurality of thinner portions are configured and arranged to improve the flexibility of the ostomy barrier.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: July 19, 2022
    Assignee: Hollister Incorporated
    Inventors: Ronald S. Botten, Christina Augustyn, Russell J. Todd, Peter L. Visconti, Heather M. Budorick, Lynn Sacramento
  • Patent number: 11389410
    Abstract: The present invention relates to a transdermal therapeutic system, comprising (a) a backing layer, (b) a solvent-based self-adhesive matrix layer containing rotigotine as active ingredient, and (c) a release liner, wherein the self-adhesive matrix layer has a coating weight of about 75-400 g/m2 and comprises a reservoir layer containing about 9-25 wt.-% rotigotine based on the weight of the reservoir layer, a kit comprising two transdermal therapeutic systems of the present invention as well as a method for the preparation of the transdermal therapeutic system of the present invention.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: July 19, 2022
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Willi Cawello, Aurelia Lappert, Kristina Kassner, Hans-Michael Wolff, Walter Müller, Johannes Josef Leonhard, Marco Emgenbroich
  • Patent number: 11389409
    Abstract: The present invention relates to transdermal devices comprising prodrugs of anti-pyretic, analgesic, or anti-inflammatory molecules, methods of making such devices, and methods of use thereof for treating, preventing, minimizing, and/or diminishing fever or pain.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: July 19, 2022
    Assignee: REMEDY DIAGNOSTICS LLC
    Inventors: Lori Ramirez, Reza Amirzadeh, Opinya Ekabo
  • Patent number: 11369615
    Abstract: A means for substantially improving mitochondrial dysfunction is provided. An aspect of the present invention relates to an agent for improving mitochondrial dysfunction, having a compound represented by the following formula, a stereoisomer or a salt thereof, or a solvate thereof, as an active ingredient. Another aspect of the present invention relates to a medicament or a pharmaceutical composition having the aforementioned compound, a stereoisomer or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof, as an active ingredient, for use in preventing or treating a disease or symptom caused by mitochondrial dysfunction.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: June 28, 2022
    Assignees: JICHI MEDICAL UNIVERSITY, TOHOKU UNIVERSITY
    Inventors: Hitoshi Osaka, Takanori Yamagata, Eriko Jimbo, Akihiko Miyauchi, Takaaki Abe
  • Patent number: 11371014
    Abstract: The present disclosure provides compositions and methods for producing hydrogel matrix constructs. Methods of using hydrogel matrix constructs for tissue repair and regeneration and for the oxygenation of red blood cells are also disclosed.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: June 28, 2022
    Assignee: William Marsh Rice University
    Inventors: Jordan Miller, Anderson Ta, Bagrat Grigoryan
  • Patent number: 11364656
    Abstract: A method of forming particles for controlled guest agent release includes coextruding first and second polymer materials to form a multilayer polymer composite sheet comprising alternating first and second polymer layers, dividing the multilayer sheet into particles, immersing the particles in a solvent containing the guest agent such that the first layers swell and the guest agent is loaded into the swollen first layers.
    Type: Grant
    Filed: July 5, 2019
    Date of Patent: June 21, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Rigoberto Advincula, Pengfei Chao, Eric Baer
  • Patent number: 11338056
    Abstract: A method for supporting repair of soft tissue with biopolymer fibers. Biopolymer is dissolved in acid in a closed container made of materials inert to the acid and to the collagen to form a biopolymer solution. The solution is stirred, then centrifuged to degas it. The degassed solution is put into syringes on a holder. The number of syringes equals the number of fibers in the bundle. The syringes are mounted in a rotatable holder. Essentially equal quantities of degassed solution are extruded from the syringes to produce fibers, which are gathered and fed into a formation buffer bath. The fibers are kept taught after extrusion and dehydrated in a dehydrating solution in a dehydrating bath. The fibers are wound a collector to collect the bundle. The fibers are used to support repair of soft tissue.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: May 24, 2022
    Assignee: EMBODY, INC.
    Inventors: Michael P. Francis, Stella Petrova, Nicholas Thayer
  • Patent number: 11338057
    Abstract: Implantable scaffolds made from biopolymer fibers. Biopolymer is dissolved in acid in a closed container made of materials inert to the acid and to the collagen to form a biopolymer solution. The solution is stirred, then centrifuged to degas it. The degassed solution is put into syringes on a holder. The number of syringes equals the number of fibers in the bundle. The syringes are mounted in a rotatable holder. Essentially equal quantities of degassed solution are extruded from the syringes to produce fibers, which are gathered and fed into a formation buffer bath. The fibers are kept taught after extrusion and dehydrated in a dehydrating solution in a dehydrating bath. The fibers are wound a collector to collect the bundle. Scaffolds then are made.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: May 24, 2022
    Assignee: Embody, LLC
    Inventors: Michael P. Francis, Stella Petrova, Nicholas Thayer
  • Patent number: 11324851
    Abstract: Absorbent materials configured to sequester trimethylamine (TMA), absorbent articles made therefrom, related methods of use, methods of measuring a reduction of free TMA, and related methods of making absorbent articles are described.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: May 10, 2022
    Assignee: INTERNATIONAL PAPER COMPANY
    Inventors: Mary Virginia Schoolfield, Hugh West
  • Patent number: 11318095
    Abstract: The present invention provides a micelle comprising an anionic micelle and a protecting agent surrounding the anionic micelle, the anionic micelle being formed from, as a structural unit, an ingredient that has a functional group capable of being anionized under basic conditions and has anionic micelle-forming ability, the protecting agent protecting the anionic micelle. The present invention also provides a micelle comprising a cationic micelle and a protecting agent surrounding the cationic micelle, the cationic micelle being formed from, as a structural unit, an ingredient that has a functional group capable of being cationized under acidic conditions and has cationic micelle-forming ability, the protecting agent protecting the cationic micelle.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: May 3, 2022
    Assignee: TEIKA PHARMACEUTICAL CO., LTD.
    Inventor: Toru Okaki
  • Patent number: 11311494
    Abstract: A formulation of a discrete liquid patch for the treatment of cold sores or viral lesions, including a combination of the adhesive layer and an active compound/ingredient such as antiviral agents, and/or amino acids, and/or minerals/vitamins. The adhesive layer of the discrete patch is substantially free of hydrocolloid particles. The adhesive layer does not include any backing layer to maintain the compliance of the patch with a thickness ranging from 5 microns to 1,300 microns. Wherein, the discrete patch of the invention is configured to apply to a viral lesion to maintain in contact therewith for a time effective to substantially complete re-epithelialization of the lesion.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: April 26, 2022
    Inventor: Adam Mark Murday
  • Patent number: 11311495
    Abstract: A transdermal therapeutic system which is free of fibrous constituents, and a method for the production of such a transdermal therapeutic system A preparation containing active substance is applied by a printing method onto the pressure-sensitive adhesive layer of the transdermal therapeutic system.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: April 26, 2022
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Reinhold Meconi, Klaus Schumann
  • Patent number: 11286372
    Abstract: The disclosed concept relates to compositions and methods for the manufacture of electrically resistive, thermally conductive electrical switching apparatus. The composition includes a polymer component and a nanofiber component. The thermal conductivity of the nanofiber component is higher than the thermal conductivity of the polymer component such that the electrical switching apparatus which includes the composition of the disclosed concept has improved heat dissipation as compared to an electrical switching apparatus constructed of the polymer component in the absence of the nanofiber component. Further, the disclosed concept relates to methods of towering the internal temperature of an electrically resistive, thermally conductive electrical switching apparatus by forming the internals of the apparatus, e.g., circuit breakers, and/or the enclosure from the composition of the disclosed concept.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: March 29, 2022
    Assignee: EATON INTELLIGENT POWER LIMITED
    Inventors: James Gerard Maloney, Edward Ethber Lias, Jeffrey Scott Gibson
  • Patent number: 11278098
    Abstract: Encapsulated hair bands and methods for use are disclosed. An encapsulated hair band includes an encapsulated hair band, including: a horseshoe shaped hair band, having a proximal and distal end, the hair band including, flexible material capable of flexing outwardly whereby the proximal and distal ends may be displaced from an unbiased position to a biased position to fit about the wearer's head; a soft gel; and a cover, including two or more pieces, cooperating to form a cover, the two or more pieces fastened together so as to encapsulate said horseshoe shaped hair band and said soft gel, said soft gel encapsulated so that when the encapsulated hair band is placed upon the wearer's head, the soft gel is between the horseshoe shaped hair band and the cover.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: March 22, 2022
    Inventor: Virginia Claire Malkin
  • Patent number: 11266534
    Abstract: The present invention generally relates to dressings such as bandages or tapes having improved extensibility and conformability to human skin and joints.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: March 8, 2022
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Marisha Gogolowski, Carmine Rizzo
  • Patent number: 11266535
    Abstract: The present invention generally relates to dressings such as bandages or tapes having improved extensibility and conformability to human skin and joints.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: March 8, 2022
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Marisha Gogolowski, Carmine Rizzo
  • Patent number: 11266361
    Abstract: A method of in vivo monitoring the condition of an internal body repair in which an imageable, non-absorbable repair device having non-absorbable, particulate imaging material substantially uniformly dispersed therein has been surgically inserted, including: in vivo sensing of dimensional deformation of said repair device during the post-surgical healing process; comparing the sensed values with a previously developed correlation between said sensed values and the values at which failure occurs of comparable repair devices; wherein said sensed values relative to the repair device's failure values, considered in conjunction with the anticipated time for complete healing of said repair, provides information as to the condition of the repair.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: March 8, 2022
    Assignee: S. JACKSON, INC.
    Inventors: Janko Jackson, Stephen L. Jackson, Crayton G. Toney
  • Patent number: 11246756
    Abstract: Single layered nonwoven wound dressings containing (1) about 5% by weight to about 95% by weight (e.g., 5% to 95%) non-scoured, non-bleached greige cotton fibers, (2) about 5% by weight to about 95% by weight (e.g., 5% to 95%) bleached cotton fibers, and (3) about 5% by weight to about 60% by weight (e.g., 5% to 60%) hydrophobic fibers (e.g., polypropylene, nylon); all percentages adding up to 100 wt %. Also, multi-layered nonwoven wound dressings, containing (1) at least one inner layer containing (a) about 50% by weight to about 95% by weight (e.g., 50% to 95) non-scoured, non-bleached greige cotton fibers and (b) about 5% by weight to about 50% by weight (e.g., 5% to 50%) hydrophobic fibers, all percentages adding up to 100 wt %, and (2) at least one outer layer containing (a) about 5% by weight to about 95% by weight (e.g., 5% to 95%) non-scoured, non-bleached greige cotton fibers, (b) about 5% by weight to about 95% by weight (e.g.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: February 15, 2022
    Assignees: The United States of America, as represented by the Secretary of Agriculture, H & H Medical Corporation, T.J. Beall Company
    Inventors: Judson V. Edwards, Joseph Dacorta, Gary Lawson
  • Patent number: 11229726
    Abstract: In some embodiments, the present invention provides methods for making resorbable ear tubes including the steps of providing a silk fibroin solution, and forming a silk ear tube from the silk fibroin solution, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbable. In some embodiments, the present invention also provides methods for treating otitis media including the step of introducing a silk ear tube into the ear canal of a subject, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbed by the subject.
    Type: Grant
    Filed: April 1, 2021
    Date of Patent: January 25, 2022
    Assignees: Tufts University, Massachusetts Eye and Ear Infirmary, The General Hospital Corporation
    Inventors: David Kaplan, Michael Whalen, Christopher Hartnick
  • Patent number: 11225582
    Abstract: A water soluble polymer composition includes a water soluble polymer and a sugar and may be used as a support in additive manufacturing processes.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: January 18, 2022
    Assignee: Infinite Material Solutions, LLC
    Inventors: Philip Brunner, Gavriel DePrenger-Gottfried, Nathan Ockwig
  • Patent number: 11220612
    Abstract: A water soluble polymer composition includes a water soluble polymer and a sugar and may be used as a support in additive manufacturing processes.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: January 11, 2022
    Assignee: Infinite Material Solutions, LLC
    Inventors: Philip Brunner, Gavriel DePrenger-Gottfried, Nathan Ockwig, Jeffrey Jacob Cernohous, Brandon J. Cernohous
  • Patent number: 11219688
    Abstract: To provide an absorption promotor that is capable of improving the efficiency in absorption of a pharmaceutical drug and that is highly stable, an absorption promotor includes an oxa acid having a structure represented by the formula (1) below, where R1 represents a linear or branched hydrocarbon group having 1 to 40 carbon atoms, one or more but not all carbon atoms of which hydrocarbon group have optionally been substituted by an oxygen atom, a nitrogen atom, or a sulfur atom, the hydrocarbon group being saturated or unsaturated; m represents a real number of 0 to 50; n represents an integer of 1 to 5; and —C(?O)—X represents a functional group capable of chemical reaction.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: January 11, 2022
    Assignee: MORESCO CORPORATION
    Inventors: Mitsuru Sugawara, Yuki Sato, Yoh Takekuma, Shingo Maruyama
  • Patent number: 11186585
    Abstract: The present invention relates to opiate derived compositions and their antagonists useful in therapeutic areas associated with opioid receptor modulation. A 3-hexadienoate modification of the opioids is formulated to improve opiates' engagement of the opioid receptors when given orally. A 3-hexadienoate modification of Nalbuphine or a pharmaceutically acceptable salt of thereof to improve quality of pain management when given intravenously, intranasally, transdermally, sublingually, rectally, topically, intramuscularly, subcutaneously or via inhalation. A 3-hexadienoate modification of the opioids antagonists is formulated to improve inhibition of the opioid receptors when given orally. A 3-hexadienoate modification of Naloxone or a pharmaceutically acceptable salt of thereof to improve quality of Sobering when given intravenously, intranasally, transdermally, sublingually, rectally, topically, intramuscularly, subcutaneously or via inhalation.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: November 30, 2021
    Assignee: Kappa-Pharma LLC
    Inventors: Georgiy Nikonov, Levon Isakulyan, Michael Voronkov
  • Patent number: 11166925
    Abstract: Improved methods and compositions are disclosed for treating dry eye by administering intranasally a therapeutically effective amount of a capsaicinoid compound embedded in multiple layers of solid lamellar crystals of monoglycerides to patients with deficient tear production. The lipophilic capsaicinoid drug is embedded in multiple layers of solid lamellar crystals of monoglycerides, and these crystals are incorporated into pharmaceutically acceptable vehicles comprised of solutions, suspensions, foams, creams, ointments, and gels. The resulting formulations of the capsaicinoid are more stable, less irritating to skin and mucous membranes, and provide increased and more controlled release of the capsaicinoid compound.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: November 9, 2021
    Assignee: ELORAC, INC.
    Inventor: Joel E. Bernstein
  • Patent number: 11168444
    Abstract: Fibrous products having an improved softness are provided, which have beneficial effects on the skin upon use. The fibrous product includes a fibrous material in which this material has at least one of lactic acid or a salt thereof in an amount of, per ply provided, in the range of from about 0.1 to about 15 g/m2, and in some embodiments, in the range of from about 1.0 to about 1.5 g/m2. A water activity of the fibrous product is from about 0.03 to 0.85. The salt of lactic acid may, for example, be sodium lactate, potassium lactate, and/or calcium lactate.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: November 9, 2021
    Assignee: Essity Hygiene and Health Aktiebolag
    Inventors: Ulrika Husmark, Lars-Erik Enarsson, Caroline Severinson
  • Patent number: 11154512
    Abstract: A hemostatic compound is provided. The hemostatic compound comprises molecular sieves and a fiber. The molecular sieves are independently dispersed on a fiber surface of the fiber without agglomeration and directly contact the fiber surface. A first surface of the molecular sieve contacted with the fiber is defined as an inner surface, and a second surface of the molecular sieve uncontacted with the fiber is defined as an outer surface. The molecular sieve forms a growth-matched coupling with the fiber on the inner surface, and the growth-matched coupling refers to that a plurality of molecular sieve microparticles grow to match the fiber surface to form a tightly-coupled coupling interface that matches the fiber surface.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: October 26, 2021
    Assignee: Hangzhou Zeo-Innov Life Technology Co., Ltd
    Inventors: Jie Fan, Lisha Yu, Liping Xiao, Hao Chen, Xiaoqiang Shang
  • Patent number: 11141360
    Abstract: Provided herein is a personal care composition that can exhibit an increased vapor release while maintaining physical stability and texture. The personal care composition can have from about 35% to about 90% petrolatum, an additional microcrystalline wax having a needle penetration at 25° C. of from about 35 to about 75 dmm, from about 1% to about 8% of a gelling agent mixture, and from about 20% to about 50% of an olfactory composition, all by weight of the composition.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: October 12, 2021
    Inventors: Stephen Bingham, Barbara Jackova, Joshua Hampton, Jason William Newlon, Jaspreet Singh Kochhar, Jayant Khanolkar, Aline Fornear
  • Patent number: 11135823
    Abstract: The invention relates to novel processes for the lamination of semi-crystalline, high-melting point, low glass transition polymeric films, which are extruded and subsequently laminated on various thermally sensitive substrates to form laminated medical device constructs in a specific time interval to allow low processing temperatures to avoid polymer film and/or substrate degradation or heat-related distortions. Also disclosed are laminated medical device constructs made from such processes.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: October 5, 2021
    Assignee: Ethicon, Inc.
    Inventors: Sasa Andjelic, Dominick Egidio
  • Patent number: 11135146
    Abstract: The present disclosure provides biophotonic topical compositions, kits and their uses. In some aspects, the biophotonic topical compositions of the present disclosure comprise a first chromophore, a salt selected from one or more bicarbonate or carbonate salts or a combination of the foregoing salts, and one or more gelling agents. In some aspects, the biophotonic topical compositions of the present disclosure comprise a first chromophore, one or more polyols, and one or more gelling agents. The biophotonic compositions of the present disclosure do not include an oxidant selected from the group consisting of a peroxide, a peroxy acid, hydrogen peroxide, carbamide peroxide, an alkali metal peroxide, an alkali metal percarbonate, peroxyacetic acid, and an alkali metal perborate. The biophotonic compositions are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various skin disorders.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: October 5, 2021
    Assignee: KLOX TECHNOLOGIES LIMITED
    Inventors: Francesco Bellini, David Ohayon, Remigio Piergallini, Nikolaos Loupis, William Curtis
  • Patent number: 11131059
    Abstract: A nanocellulose composite sheet, comprising a moisturized nanocellulose material and a fabric is disclosed. The moisturized nanocellulose material and the fabric are bonded by mechanical adhesion. A method for manufacturing the nanocellulose composite sheet for use as a dermatological treatment or medical device, and an apparatus for manufacturing the nanocellulose composite sheet are also provided. The nanocellulose composite sheet has contour conformability, excellent skin-adhesion, and high capacity for moisture retention and release, and is ideal for dermatological treatments.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: September 28, 2021
    Assignee: Innovatech Engineering LLC
    Inventors: Raghuram Dhumpa, Ali Darkazalli
  • Patent number: 11129798
    Abstract: At present, the most prevalent pharmaceutical dosage forms, the oral immediate-release tablets and capsules, are granular solids. The problem of such solids is that their microstructure and properties are not predictable from physical models. As a consequence, product development and manufacture are resource-intensive and time-consuming, and quality control is statistical by testing instead of by design. Furthermore, the range of the drug release rate, and the variety of active ingredients that can be processed to a functional product, are limited in such dosage forms. Presented herein, accordingly, is a fibrous dosage form suitable for immediate-release applications prepared by a predictable liquid-based process. The fibrous dosage form includes a drug-containing solid comprising a three dimensional structural network of one or more drug-containing fibers.
    Type: Grant
    Filed: April 9, 2017
    Date of Patent: September 28, 2021
    Inventor: Aron H. Blaesi
  • Patent number: 11116769
    Abstract: The present disclosure relates to a film formulation for oral administration, containing tadalafil free base and a method of preparing the same, and a film may be provided with maximized dispersion stability of tadalafil free base in the film by the addition of a dispersion stabilizing agent in small amounts without unique fragrance or favor that may appear when other dispersion stabilizing agents known in the art are used, and an extremely low likelihood that a reagglomeration phenomenon of tadalafil free base particles will occur, and an amount of bubbles generated may be significantly reduced during a production process.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: September 14, 2021
    Assignee: CTC BIO, INC.
    Inventors: Hong Ryeol Jeon, Do-Woo Kwon, Bong-Sang Lee, Su-Jun Park, Bong-Geun Cha, Jun-Ki Kim, Jiyeong Han, Myeongcheol Kil
  • Patent number: 11116443
    Abstract: Systems and methods for accurately and efficiently diagnosing, assessing, staging/grading/categorizing, and treating pressure ulcers, as well as preventing reverse staging of pressure ulcers, are disclosed. The system, in one embodiment, ensures that the rationale for the stage assigned to the patient will be in the patients' medical record. The system, in various embodiments, further suggests the pressure ulcer classification and allows the user to choose which classification terms should be used. In various embodiments, the system also allows for the different classification/staging system guidelines to be used, including the National Pressure Ulcer Advisory Panel (NPUAP) guidelines, the European Pressure Ulcer Advisory Panel Guidelines (EPUAP), the Pan Pacific Pressure Injury Alliance, CMS, WHO, and the MDS Guidelines.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: September 14, 2021
    Assignee: Universal Care Solutions, LLC
    Inventor: Candice Ganey Curtin
  • Patent number: 11109975
    Abstract: A scaffold is provided which facilitates integration of both bone and cartilage at an osteochondral lesion, thereby acting as a tissue engineered interface or tissue engineered junction between the two different tissues. The method and systems for engineering this interface may be acellular or may be loaded with cells prior to use.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: September 7, 2021
    Assignee: Cytex Therapeutics, Inc.
    Inventors: Bradley T. Estes, Franklin Thomas Moutos, Farshid Guilak
  • Patent number: 11102979
    Abstract: An antimicrobial article that includes: an antimicrobial composite region that includes a matrix comprising a polymeric material, and a first plurality of particles within the matrix. The particles include a phase-separable glass with a copper-containing antimicrobial agent. The antimicrobial composite region can be a film containing the first plurality of particles that is subsequently laminated to a bulk element. The first plurality of particles can also be pressed into the film or a bulk element to define an antimicrobial composite region. An exposed surface portion of the antimicrobial composite region can exhibit at least a log 2 reduction in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, and Pseudomonas aeruginosa bacteria under a Modified EPA Copper Test Protocol.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: August 31, 2021
    Assignee: Corning Incorporated
    Inventors: Dayue Jiang, Kevin Andrew Vasilakos, Frederic Christian Wagner, Carlo Anthony Kosik Williams
  • Patent number: 11101463
    Abstract: A copolymer for binders, which is capable of reducing the internal resistance of a battery, while ensuring sufficient binding properties between active materials and between an active material and a collector in a nonaqueous battery electrode; a composition for binders; a slurry for nonaqueous battery electrodes; a nonaqueous battery electrode; and a nonaqueous battery. This copolymer for binders is a copolymer for binders (P) of a monomer mixture (M) that contains at least a monomer (A) represented by general formula (1) and a (meth)acrylate salt monomer (B); and an amount of structure derived from the monomer (A) based on the copolymer for binders (P) is set to 0.5 to 20.0% by mass. (In the formula, each of R1 and R2 independently represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: August 24, 2021
    Assignee: SHOWA DENKO K.K.
    Inventors: Mitsuru Hanasaki, Yasuhiro Nakagawa
  • Patent number: 11098441
    Abstract: A method is provided for producing a fiber fabric by preparing a finishing agent treatment liquid having a mixture of first and second particles of titanium oxide having a particle diameter of 150 to 200 nm and 1 to 5 ?m respectively, a silver zeolite and a binder resin, immersing a fiber fabric in the finishing agent, thermal drying the fiber fabric and subjecting the fiber fabric to heat treatment to allow the finishing agent to adhere to the fiber fabric.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: August 24, 2021
    Assignee: AS CORPORATION
    Inventor: Shigeru Nohara
  • Patent number: 11078521
    Abstract: The present invention and embodiments thereof relates to compositions and methods for storage, stabilization and preservation of biological samples and/or nucleic acids on a solid matrix. Methods for extracting, collecting, and recovering the biological samples and/or nucleic acids from the solid matrix are also described.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: August 3, 2021
    Assignee: BIOMATRICA, INC.
    Inventors: Joel Desharnais, Daniela Roth, Vasco Liberal
  • Patent number: 11071745
    Abstract: The present disclosure provides compositions and methods for the prevention of HSV infection in an HSV seronegative individual.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: July 27, 2021
    Assignee: ELIAN LLC
    Inventors: Emidio A. Checcone, Christina Ramirez
  • Patent number: 11065295
    Abstract: Compositions and methods are presented in which a plurality of chemically distinct polyphenols inhibit multiple enzymes in pathways associated with health and healthy ageing. Preferred compositions are derived from colored plant materials that are commonly found in the Mediterranean diet and provide the biochemical basis for the health benefits of the Mediterranean diet. Notably, the enzyme inhibition observed with the combined polyphenols was synergistic with respect to not one but a significant number of enzymes in the pathways associated with health and healthy ageing, thus providing an amplified desirable effect.
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: July 20, 2021
    Assignee: DAILYCOLORS HEALTH INC.
    Inventor: Hartley Pond
  • Patent number: 11045518
    Abstract: Compositions and methods are presented in which a plurality of chemically distinct polyphenols inhibit multiple enzymes in pathways associated with health and healthy ageing. Preferred compositions are derived from colored plant materials that are commonly found in the Mediterranean diet and provide the biochemical basis for the health benefits of the Mediterranean diet. Notably, the enzyme inhibition observed with the combined polyphenols was synergistic with respect to not one but a significant number of enzymes in the pathways associated with health and healthy ageing, thus providing an amplified desirable effect.
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: June 29, 2021
    Assignee: DAILYCOLORS HEALTH INC.
    Inventor: Hartley Pond
  • Patent number: 11040043
    Abstract: The present invention provides compositions and methods for providing sustained release of an active agent through the skin of a subject, wherein a pharmaceutical percutaneous composition comprises at least one fatty acid ester and a therapeutically effective amount of active agent.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: June 22, 2021
    Assignee: BESINS HEALTHCARE LUXEMBOURG SARL
    Inventors: Valerie Masini-Eteve, Denis Canet
  • Patent number: 11033512
    Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising an asenapine-containing layer structure, said asenapine-containing layer structure comprising A) a backing layer and B) an asenapine-containing layer, wherein the transdermal therapeutic system comprises a silicone acrylic hybrid polymer.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: June 15, 2021
    Assignee: LTS LOHMANN THERAPIE-SYSTEME AG
    Inventors: Patrick Mohr, René Rietscher, René Eifler, Olga Bourquain