Ammonia, Amine, Or Derivative Thereof (e.g., Urea, Etc.) Patents (Class 424/54)
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Publication number: 20140120142Abstract: The present invention relates to compositions and methods for calcifying dental tissue, e.g., preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.Type: ApplicationFiled: September 23, 2013Publication date: May 1, 2014Applicant: The Research Foundation of State University of New YorkInventors: Israel Kleinberg, Ana Marie Acevedo, Robi Chatterjee
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Publication number: 20140099347Abstract: The invention includes a dentifrice composition that comprises a zinc ion source, a polyphosphate ion source, an anethole and a silica. The silica has a mean particle size of about 5 to about 12 microns, an Einlehner hardness of about 1 to about 20, and an oil absorption of about 40 to less than about 100 cc/100 g. The composition contains zinc ions and polyphosphate ions in a weight ratio of about 0.1:1 to about 10:1 and has a RDA value of about 100 to about 200 and a PCR value of about 75 to about 110. Related methods are also included.Type: ApplicationFiled: December 6, 2013Publication date: April 10, 2014Applicant: Colgate-Palmolive CompanyInventor: Michael Prencipe
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Publication number: 20140079650Abstract: The present invention relates to a phosphopeptide-stabilized amorphous calcium phosphate and/or amorphous calcium fluoride phosphate complex, wherein the complex is formed at a pH of below 7.0. Methods of making such complexes are also provided. The complexes are useful in dental applications, in particular in dental remineralisation.Type: ApplicationFiled: November 12, 2013Publication date: March 20, 2014Applicant: The University of MelbourneInventor: Eric Charles REYNOLDS
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Publication number: 20140065081Abstract: The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, said fragrance precursor compounds being of the formula X—O—C(R)(R*)(OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precursors. Further the invention relates to compositions, comprising the precursor of the invention.Type: ApplicationFiled: September 23, 2013Publication date: March 6, 2014Applicant: Colgate-Palmolive CompanyInventors: Daniel W. Smith, Amjad Farooq, Donghui Wu, Marija Heibel, Karen Drehs
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Publication number: 20140056951Abstract: Methods of treating or reducing biofilms, treating a biofilm-related disorder, and preventing biofilm formation using polyamines is described.Type: ApplicationFiled: November 4, 2013Publication date: February 27, 2014Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Richard LOSICK, Illana KOLODKIN-GAL, Jon CLARDY, Shugeng CAO, Matt CABEEN, Roberto KOLTER, Liraz CHAI, Thomas BÖTTCHER
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Publication number: 20140056949Abstract: Formulations for chemoprevention of oral cancer and precancerous lesions, and for methods for preparing the formulations are described.Type: ApplicationFiled: November 15, 2011Publication date: February 27, 2014Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE OHIO STATE UNIVERSITYInventors: Susan R. Mallery, Peter E. Larsen, Gary D. Stoner, Steven P. Schwendeman, Kashappa-Goud Desai
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Publication number: 20140044650Abstract: A composition is provided, wherein the composition comprises a water-swellable, water-insoluble polymer or a water-soluble polymer, a blend of a hydrophilic polymer and a complementary oligomer capable of hydrogen bonding to the hydrophilic polymer. The composition also includes a second water-swellable, water-insoluble polymer that provides for a phase separating film forming composition. Active ingredients, such as a whitening agent, may be included. The composition finds utility as an oral dressing, for example, a tooth whitening composition that is applied to the teeth in need of whitening, and removed when the degree of whitening has been achieved. In certain embodiments, the composition is translucent. Methods for preparing and using the compositions are also disclosed.Type: ApplicationFiled: September 6, 2013Publication date: February 13, 2014Applicants: CORIUM INTERNATIONAL, INC., A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESISInventors: Parminder Singh, Gary W. Cleary, Sri Mudumba, Mikhail M. Feldstein, Danir R. Bairamov
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Patent number: 8647608Abstract: Dental compositions are provided comprising a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein n is an integer from about 2 to about 5.Type: GrantFiled: October 31, 2012Date of Patent: February 11, 2014Assignee: 3M Innovative Properties CompanyInventors: Jie Yang, Bhaskar V. Velamakanni, Sumita B. Mitra, Alphonsus V. Pocius, John J. Stofko, Jr., Jeremy M. Yarwood
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Publication number: 20140023598Abstract: The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, said fragrance precursor compounds being of the formula X—O—C(R)(R*)(OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precusors. Further the invention relates to compositions, comprising the precursor of the invention.Type: ApplicationFiled: September 23, 2013Publication date: January 23, 2014Applicant: Colgate-Palmolive CompanyInventors: Daniel W. Smith, Amjad Farooq, Donghui Wu, Marija Heibel, Karen Drehs
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Publication number: 20140010767Abstract: This document provides methods and materials for providing teeth with a white appearance. For example, methods and materials for contacting teeth with one or more fluorescence emitting polypeptides (e.g., a blue fluorescent protein (BFP)) to provide the teeth with a whiter appearance are provided.Type: ApplicationFiled: September 17, 2013Publication date: January 9, 2014Applicant: SafeWhite LLCInventors: Scott Joseph Bridgeman, Richard Simon Brody, Thomas Joel Zupancic
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Patent number: 8623334Abstract: A topical anesthetic is provided containing about 3 wt % to 10 wt % tetracaine in a vehicle suitable for administration to the mucosa. The vehicle for transporting the tetracaine includes a water soluble mucoadhesive or a combination of mucoadhesives such as a high molecular weight poly(ethylene oxide) homopolymer and a cellulose polymer. The vehicle also includes propylene glycol. The tetracaine is ground into a powder and is suspended in a plasticized hydrocarbon gel which completes the vehicle.Type: GrantFiled: September 10, 2012Date of Patent: January 7, 2014Inventors: Alan J. Wickenhauser, Stephen E. Peipert
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Publication number: 20130344011Abstract: Disclosed are oral care compositions having reduced tooth staining propensity and comprising in a pharmaceutically acceptable carrier, a cationic antimicrobial agent and an anti-stain agent comprising one or more materials from each of at least two of the following chemical groups: Group 1. anionic agents, Group 2. aldehydes, ketones, and other reactive carbonyl compounds and Group 3. nonionic ethoxylated surfactants. Examples of cationic antimicrobial agent include quaternary ammonium compounds such as cetylpyridinium chloride, cetyl pyridinium fluoride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride and domiphen bromide; chlorhexidine; and metal ion sources to supply metal ions such as stannous, zinc or copper.Type: ApplicationFiled: June 21, 2012Publication date: December 26, 2013Inventors: Niranjan Ramji, Douglas Craig Scott
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Publication number: 20130344120Abstract: Disclosed are oral care mouth rinse compositions formulated as stable oil-in-water emulsions comprising: (a) at least about 0.025% by weight of a quaternary ammonium antimicrobial agent, (b) at least about 0.05% by weight of an essentially water-insoluble volatile oil, and (c) at least about 50% by weight water, wherein the emulsion comprises oil droplets having an average mean particle size of about 350 nm or less. Examples of quaternary ammonium antimicrobial agent include cetylpyridinium chloride (CPC), tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide.Type: ApplicationFiled: June 21, 2012Publication date: December 26, 2013Inventors: Douglas Craig Scott, Niranjan Ramji, Bruce Ernest Tepper
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Publication number: 20130330283Abstract: Flavour components for use in oral care compositions containing a metal salt, compositions comprising the flavour components, and methods of making and using the same. The flavour components comprise a taste -masking agent comprising cinnamic aldehyde, eugenol and eucalyptol and one or more flavouring agents selected from L-menthol, N-ethyl-p-menthane-3-carboxamide, anethole, peppermint oil, spearmint oil and corn mint oil. In particular the metal salt is zinc citrate.Type: ApplicationFiled: February 15, 2011Publication date: December 12, 2013Applicant: COLGATE-PALMOLIVE COMPANYInventors: Robert Vogt, Karsten Kohrs, Steven Wade Fisher, Thomas Campbell, Michael Prencipe
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Publication number: 20130330116Abstract: Disclosed are compositions suitable for use with an oral care implement. The compositions provide improved sensory appeal, and comparable reduction in volatile sulfur compounds and antibacterial activity to advanced formula toothpaste formulations. The compositions include a high percentage of antibacterial agent and flavoring, when compared to conventional toothpastes, and some mouth washes formulations, such that only minor amounts of the composition can be delivered to the oral care implement to provide improved reduction in volatile sulfur compounds, antibacterial efficacy, and optionally a cooling sensation.Type: ApplicationFiled: July 30, 2010Publication date: December 12, 2013Inventors: Sarita Mello, Madhusudan Patel, Sharon Kennedy, Thomas Boyd, Evangelia S. Arvanitidou, James R. Brown, Suman Chopra
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Patent number: 8597618Abstract: Disclosed is a dentifrice composition comprising an orally acceptable vehicle, an abrasive particulate and a surfactant system comprising an anionic surfactant comprising a C8-C16 fatty acid glutamate salt and a nonionic surfactant comprising a C8-C16 alkyl glucoside.Type: GrantFiled: December 6, 2012Date of Patent: December 3, 2013Assignee: Tom's of Maine, Inc.Inventors: Tammy Swett, Julie Venell, Chantal Bergeron, Mark Dobrovolny, Stefan Gafner
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Publication number: 20130315844Abstract: Described herein are compositions comprising an active compound from an extract of magnolia, or a derivative thereof; and a non-surfactant electrolyte in an amount effective to stabilize the composition, and methods of making and using the same.Type: ApplicationFiled: January 31, 2011Publication date: November 28, 2013Applicant: COLGATE-PALMOLIVE COMPANYInventors: Shyamala Pillai, Lin Fei, Guofeng Xu
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Patent number: 8580232Abstract: An enhancing composition comprising a solvent and a base compound creates an alkaline environment for activating peroxide whiteners and accelerating the formation of free radicals from the peroxide to effect the oxidation of organic molecules causing staining of the dentition. In one embodiment, potassium hydroxide is dissolved in water to form a strongly alkaline liquid. A surfactant may also be included to clean the surfaces of the user's teeth in advance of application of the whitening composition. A peroxide may be added to the enhancing composition to provide a tooth whitening. Other additives for taste, texture, viscosity, and other oral care or oral hygiene purposes may also be included in the enhancing composition. The enhancing composition may be used for advance application to the dentition before a whitening compound. In addition, a rinse may be used after the whitening composition to neutralize the alkaline environment.Type: GrantFiled: December 16, 2010Date of Patent: November 12, 2013Inventor: Martin S. Giniger
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Patent number: 8568698Abstract: This document provides methods and materials for providing teeth with a white appearance. For example, methods and materials for contacting teeth with one or more fluorescence emitting polypeptides (e.g., a blue fluorescent protein (BFP)) to provide the teeth with a whiter appearance are provided.Type: GrantFiled: August 24, 2011Date of Patent: October 29, 2013Assignee: SafeWhite LLCInventors: Scott Joseph Bridgeman, Richard Simon Brody, Thomas Joel Zupancic
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Publication number: 20130280184Abstract: Methods of preparing a dentifrice comprising polymer matrix film with a low solubility flavorant therein are disclosed. The methods comprise combining a polymer matrix film that are free of a low solubility flavorant with a dentifrice base comprising a low solubility flavorant and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed.Type: ApplicationFiled: December 13, 2010Publication date: October 24, 2013Applicant: Colgate-Palmolive CompanyInventors: Ben Gu, Mahmoud Hassan
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Publication number: 20130269133Abstract: An encapsulated oral care composition includes: (a) a gelatin capsule; and (b) a oral care composition contained within the capsule, and including: (i) a hydrophilic active; (ii) a hydrophobic structuring agent; and (iii) an oil carrier. The hydrophilic active is preferably cetylpyridinium chloride. The hydrophobic structuring agent is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the encapsulated oral care composition such that the capsule releases the oral care composition to clean the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and the encapsulated oral care composition positioned on the head.Type: ApplicationFiled: December 20, 2010Publication date: October 17, 2013Applicant: Colgate-Palmolive CompanyInventors: Dennis Kembero Ontumi, Thomas James Boyd, Suman Kumar Chopra, James Richard Brown
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Publication number: 20130272972Abstract: Described herein are compositions comprising a quinone and one or more antibacterial agents, and methods of preparing and using the same.Type: ApplicationFiled: December 7, 2010Publication date: October 17, 2013Applicant: Colgate-Palmolive CompanyInventors: Laurence Du-Thumm, Lyndsay Schaeffer- Korbylo, David Santos, Stanislav Jaracz
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Publication number: 20130269132Abstract: A oral care composition includes: (a) a guanidine active; (b) a film-forming polymer; (c) a hydrophobic viscosity modifier in an amount sufficient to provide the oral care composition with a particle settling time greater than 20 minutes; and (d) an oil carrier. The guanidine active is preferably L-arginine. The film-forming polymer is preferably GANTREZ. The hydrophobic viscosity modifier is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the oral care composition cleans the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.Type: ApplicationFiled: December 20, 2010Publication date: October 17, 2013Applicant: Colgate-Palmolive CompanyInventors: Dennis Kembero Ontumi, Sarita Vera Mello, Suman Kumar Chopra, James Richard Brown, Thomas James Boyd, Rahul Patel
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Publication number: 20130273126Abstract: A method for forming a tooth bleaching catalytic is provided, wherein the method comprises steps as follows: Firstly a plurality of histidine-functionalized mesoporous silica nano-particles (MSNs) is provided. Subsequently, the histidine-functionalized MSNs are condensating with a plurality of metal ions.Type: ApplicationFiled: June 7, 2013Publication date: October 17, 2013Inventors: Chia-Wen WU, Bor-Shiunn LEE, Li-Chun HUANG, Chun-Pin LIN
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Publication number: 20130251647Abstract: The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.Type: ApplicationFiled: September 20, 2012Publication date: September 26, 2013Applicant: BASF SEInventors: Thomas Subkowski, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel, Ralf Pelzer
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Publication number: 20130251648Abstract: A thick cleaning composition, comprising a long-chain fatty acyl acidic amino acid ester; a fatty compound of fatty acid, fatty alcohol, fatty alcohol ether or polyol fatty acid ester; a surfactant; a solvent composed of water, lower alcohol, polyol and polyol ether; and further comprising a beautifying and cleaning adjuvant for skin, eyes, teeth and hair. The cleaning composition can achieve satisfactory thick appearance when used for cleaning skin and hair, and maintain stable viscosity at different temperatures. In use, the composition can be easily daubed, and foams quickly with good foaming quality.Type: ApplicationFiled: November 3, 2011Publication date: September 26, 2013Applicant: Suzhou Yuansuji Chemical Industry Co., Ltd.Inventors: Haiyang Tong, Jun Lu, Anjian Hui
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Publication number: 20130230469Abstract: This invention relates to a mouthwash comprising an aqueous solution of an effective amount of an orally acceptable, soluble zinc salt together with an effective amount of a preservative selected from methylisothiazolinone (MIT), benzyl alcohol, glycerol monocaprylate, and combinations thereof; as well as to methods of using and of making such compositions.Type: ApplicationFiled: November 12, 2010Publication date: September 5, 2013Applicant: COLGATE-PALMOLIVE COMPANYInventors: Catherine Lewus, Gregory Szewczyk, Sarita Mello, Kimdra Smith-Webster, Jason Nesta, Rensl Dillon, Evangelia S. Arvanitidou, Christine Cuiule
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Publication number: 20130224128Abstract: The present invention relates to a dental cleanser composition for improving adhesion to teeth, and more particularly to, a dental cleanser composition which functions to remove not only a smear layer from the dentin surface of an exposed tooth root, but also oral bacteria, and thus is effective in improving adhesion to teeth in periodontal surgery. The present invention provides a dental cleanser composition containing sodium ethylene diaminotetraacetate and octyl phenol ethoxylate which is a surfactant. Sodium ethylene diaminotetraacetate in the composition functions to remove a smear layer on the tooth root surface and has antibacterial activity, and octyl phenol ethoxylate in the composition functions to lipopolysaccharide. Thus, the composition improves adhesion to teeth in periodontal surgery.Type: ApplicationFiled: February 28, 2011Publication date: August 29, 2013Applicant: NANO INTELLIGENT BIOMEDICAL ENGINEERING CO., LTD.Inventors: Chong-Pyoung Chung, Yoon-Jeong Park, Jue-Yeon Lee
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Publication number: 20130224270Abstract: This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and an abrasive system comprising natural calcium carbonate and precipitated calcium carbonate; and to methods of using and of making these compositions.Type: ApplicationFiled: October 27, 2010Publication date: August 29, 2013Applicant: Colgate-Palmolive CompanyInventors: Richard Robinson, Eric Simon
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Publication number: 20130224125Abstract: An aqueous, heat and cold stable, non-alcoholic or slightly-alcoholic microemulsion based antimicrobial mouthwash composition with improved antimicrobial efficacy. The composition comprises a unique water-soluble matrix composite, at least one water-immiscible or water-insoluble antimicrobial agent, and optionally, a preservative or preservative system, a weak carboxylic acid, a coloring agent and other additives. Examples of antimicrobial agents include menthol, thymol, eucalyptol and/or methyl salicylate. A process for preparing the oral care composition is also disclosed.Type: ApplicationFiled: July 19, 2011Publication date: August 29, 2013Inventors: Narayanan S. Kolazi, William E. Prosise, Robert J. Corring
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Publication number: 20130224126Abstract: This invention relates to a mouthwash comprising an aqueous solution of an effective amount of a basic amino acid, in free or salt form together with an effective amount of a preservative selected from methylisothiazolinone (MIT), benzyl alcohol, phenoxyethanol, and combinations thereof; as well as to methods of using and of making such compositions.Type: ApplicationFiled: November 12, 2010Publication date: August 29, 2013Applicant: Colgate-Palmolive CompanyInventors: Catherine Lewus, Gregory Szewczyk, Sarita Mello, Kimdra Smith-Webster, Jason Nesta, Rensl Dillon, Evangelia S. Arvanitidou, Christine Cuiule
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Publication number: 20130216595Abstract: In order to obtain steady erosion from soluble tablets and particularly constant dispersion of contained abrasive media, the employment of magnesium oxide and transverse interlaced polyvinylpyrrolidone (PVP) in defined layers and the admixing of randomly scattered silicic acids is suggested.Type: ApplicationFiled: June 10, 2011Publication date: August 22, 2013Inventor: Daniel Mueller
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Publication number: 20130216486Abstract: The present invention provides synthetic routes for preparing various isomers of cyclohexane-based coolants, such as menthyl esters and menthanecarboxamide derivatives, in particular those substituted at the amide nitrogen, for example with an aromatic ring or aryl moiety. Such structures have high cooling potency and long lasting sensory effect, which make them useful in a wide variety of consumer products. One synthetic route involves a copper catalyzed coupling of a primary menthanecarboxamide with an aryl halide, such reaction working best in the presence of potassium phosphate and water. Using this synthetic route, specific isomers can be prepared including the menthanecarboxamide isomer having the same configuration as l-menthol and new isomers such as a neoisomer having opposite stereochemistry at the carboxamide (C-1) position. The neoisomer unexpectedly has potent and long lasting cooling effect.Type: ApplicationFiled: March 20, 2013Publication date: August 22, 2013Applicant: The Procter & Gamble CompanyInventor: The Procter & Gamble Company
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Publication number: 20130183252Abstract: The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals.Type: ApplicationFiled: February 10, 2012Publication date: July 18, 2013Applicant: Senomyx, Inc.Inventors: Xiaodong LI, Andrew Patron, Catherine Tachdjian, Hong Xu, Qing Li, Alexey Pronin, Guy Servant, Lan Zhang, Thomas Brady, Vincent Darmohusodo, Melissa Arellano, Victor Selchau, Brett Weylan Ching, Donald S. Karanewsky, Paul Brust, Jing Ling, Wen Zhao, Chad Priest
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Publication number: 20130177507Abstract: An improved special molecule provides a useful composition with following formula: R1 R2 . . . C . . . wherein: R1 is a phenyl hydrazine PM 108.14 C is a Leucine 131.17 R2 is a methyl piperazina 111 100.16 339.69. The user friendly molecule inhibits Streptococcus mutans bacteria responsible for tooth decay and is especially useful in products used in oral hygiene.Type: ApplicationFiled: January 5, 2013Publication date: July 11, 2013Inventor: José Luis Córdova Rojas
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Patent number: 8475773Abstract: The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2. In another aspect of the present invention, a method for improving oral hygiene in a mammal is provided. The method involves taking a volume of a solution into the mammal's mouth, where the solution includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm2, swishing the solution around and expelling the solution.Type: GrantFiled: June 9, 2012Date of Patent: July 2, 2013Assignee: Mineral Science Co.Inventor: Brian Giles
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Patent number: 8475771Abstract: A dentifrice composition comprising an orally acceptable vehicle having distributed therein a water hydratable film flakes having a matrix comprised of a water soluble hydroxy alkyl cellulose polymer and a starch, and having entrained therein a constituent selected from therapeutic cosmetic and decorative materials.Type: GrantFiled: December 31, 2007Date of Patent: July 2, 2013Assignee: Colgate-Palmolive CompanyInventors: Thomas J. Boyd, Guofeng Xu, M. Teresa R. Carale
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Publication number: 20130164358Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.Type: ApplicationFiled: August 5, 2011Publication date: June 27, 2013Inventors: Marvin Cohen, Susanne Cohen, Robert G. Flynn
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Publication number: 20130164228Abstract: Described herein are compositions for topical use comprising an antibacterially effective concentration of a gallate or gallamide compound which is a polysubstituted cycloalkyl or heterocycloalkyl wherein the substituents are selected from hydroxy, hydroxymethyl, fluoro, chloro, amino, nitro, or a moiety of formula -X-(CO)-(3,4,5-trihydroxyphenyl), wherein X is selected from O and NH, provided that the substituents comprise at least two moieties of formula -X-(CO)-(3,4,5-trihydroxyphenyl) attached to adjacent carbons in free or in orally or topically acceptable salt form, as well as methods of making and using the same.Type: ApplicationFiled: December 21, 2011Publication date: June 27, 2013Applicant: Colgate-Palmolive CompanyInventors: Stanislav Jaracz, Guofeng Xu, Steven Miller, Leonora Leigh, Guillaume Picquet, Laurence Du-Thumm
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Publication number: 20130142736Abstract: Described herein, are compositions comprising an effective amount of a basic amino acid in free or salt form, and a water soluble strontium salt; and methods of making and using the same.Type: ApplicationFiled: August 18, 2010Publication date: June 6, 2013Applicant: Colgatge-Palmolive CompanyInventors: Richard Scott Robinson, Richard J. Sullivan, Rajnish Kohli
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Publication number: 20130129642Abstract: The invention provides an oral care composition suitable for delivering a temporary whitening effect to the surface of teeth, the composition comprising: a continuous phase comprising water or polyhydric alcohol or a mixture thereof; a tooth surface whitening agent which is dispersed in the continuous phase, and a deposition aid for the tooth surface whitening agent; characterised in that the tooth surface whitening agent is a lake dye formed by fixing a dye onto a particulate inorganic substrate, in which the dye used to form the lake dye is a triarylmethane dye having a blue to green-blue colour with a hue angle in the CIELAB system ranging from 180 to 270 degrees, and in which the amount of lake dye is at least 0.015% by total weight lake dye based on the total weight of the composition.Type: ApplicationFiled: July 28, 2011Publication date: May 23, 2013Inventors: Andrew Joiner, Carole Jane Philpotts
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Publication number: 20130129639Abstract: This invention relates to a cationically and hydrophobically modified polygalactomannan having repeating units with a D-mannosyl to D-galactosyl residue ratio of at least 5 to 1 and to compositions containing same. A portion of the hydrogen atoms of hydroxyl groups situated on the mannosyl and galactosyl residues of the galactomannan are replaced with a hydrophobic substituent and a cationic substituent.Type: ApplicationFiled: April 28, 2011Publication date: May 23, 2013Applicant: LUBRIZOL ADVANCED MATERIALS, INC.Inventors: Eric H. Anderson, Carole A. Lepilleur, Dennis N. Malaba, John J. Mullay, Denise W. Rafferty, Duane G. Krzysik, Xin Liu
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Publication number: 20130108560Abstract: A thin film composition for oral administration that adheres to and dissolves in a mouth of a user, wherein the thin film is a single layered water-soluble solid comprising at least one D-amino acid contained in a plurality of hydrophobic carriers dispersed throughout the thin film. The hydrophobic carriers comprise oil and the composition further comprises a phospholipid, an emulsifier, and a water soluble polymer. The preferred D-amino acids are D-leucine, D-tryptophan, D-methionine, and D-tyrosine. A method of reducing dental plaque in a subject entails placing the thin film composition contemplated herein into a mouth of the subject.Type: ApplicationFiled: November 1, 2012Publication date: May 2, 2013Inventors: Robert Davidson, Eric Allen, Ed Maliski
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Publication number: 20130084254Abstract: The invention provides a non-aerated, foamable oral care composition comprising less than 1.5% anionic surfactant (by total weight anionic surfactant based on the total weight of the composition), abrasive cleaning agent and hydrophobin. The composition is mild to oral mucosa yet exhibits excellent foamability, texture and storage stability.Type: ApplicationFiled: May 13, 2011Publication date: April 4, 2013Inventors: Coralie Claudine Alonso, Alison Katharine Green, Jordan Todorov Petkov, Pierre Starck
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Publication number: 20130078197Abstract: Disclosed are therapeutic oral compositions useful in the treatment of a variety of oral disorders, in which the composition can provide blockage of dentinal tubes, while at the same time provide antibacterial and anti-caries efficacy. The compositions include arginine in free or salt form, a mucoadhesive polymer, and at least one component selected from pyrophosphates, zinc salts, potassium salts, strontium salts, and mixtures thereof.Type: ApplicationFiled: June 23, 2010Publication date: March 28, 2013Applicant: COLGATE-PALMOLIVE COMPANYInventors: Sarita V. Mello, Evangelia Arvanitidou
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Publication number: 20130071439Abstract: Methods of treating or reducing biofilms, treating a biofilm-related disorder, and preventing biofilm formation using D-amino acids are described.Type: ApplicationFiled: January 10, 2011Publication date: March 21, 2013Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Richard Losick, Jon Clardy, Roberto Kolter, Illana Kolodkin-Gal, Diego Romero, Shugeng Cao
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Publication number: 20130064778Abstract: The present invention is directed towards a composition for highly efficient and quick plaque and tartar removal and inhibition including pure ascorbic acid crystals and/or granulars (vitamin C) and an enamel repairing composition such as hydroxyapatite. The composition can contain from about 10% up to 90% of ascorbic acid without compromising the tooth enamel because hydroxyapatite will repair any damage to the enamel. The composition can be used as dental powder, toothpaste, mouthwash, mouth spray and chewing gum in order to cover a wide range of consumers in different settings.Type: ApplicationFiled: February 17, 2012Publication date: March 14, 2013Inventors: Joseph Riina, Charles Leonhardt
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Publication number: 20130064779Abstract: Described herein are compositions which prevent the growth of bacteria resistant to high salt concentrations, methods of preparing the same, and methods of using the same.Type: ApplicationFiled: June 1, 2010Publication date: March 14, 2013Applicant: Colgate-Palmolive CompanyInventors: Odete Tieko Yamane, Fernanda Cristina Geraldo Correa, Sandra Pereira Ramos, Katrin Chaves Da Costa, Enzo Toshio Utima, Erico Vieira Prat, Michael Prencipe, Richard Scott Robinson
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Publication number: 20130052146Abstract: Dental compositions are provided comprising a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein n is an integer from about 2 to about 5.Type: ApplicationFiled: October 31, 2012Publication date: February 28, 2013Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventor: 3M Innovative Properties Company
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Publication number: 20130039866Abstract: The invention solves the problem of the practical realization of an effective prophylactic composition which uses available and safe components and which can be recommended for preventing the growth of candidiasis of the skin and/or mucous membranes in humans in the following risk group: sufferers of diabetes mellitus, people with blood diseases, immune deficiency and other serious pathologies, patents after a course of hormone therapy, antibiotic treatment or chemotherapy, as well as for babies and pregnant women; and for people using tooth implants. The composition for the prophylaxis of candidiasis comprises active components, with the active components used being xylitol in a quantity of 0.3-20.0% by mass and sodium or potassium alginate or a mixture thereof in a quantity of 0.01-2.0% by mass, as well as inert components.Type: ApplicationFiled: June 9, 2011Publication date: February 14, 2013Applicant: Obshchestvo S Ogranichennoj Otvetstvennostyu "WDS"Inventors: Tamaz Omarovich Manasherov, Svetlana Konstantinovna Matelo, Tat'yana Vladimirovna Kupets