Sodium Containing Or Fluorine Containing Patents (Class 424/606)
  • Patent number: 10634656
    Abstract: A standard for testing measurement systems for aqueous chlorine species analysis includes an openable storage vessel and an aqueous composition including a compound having the formula R1R2NCl where R1 and R2 are independently methyl, ethyl or propyl, wherein the aqueous composition is storage stable within the openable storage vessel.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: April 28, 2020
    Assignee: HACH COMPANY
    Inventor: Darren MacFarland
  • Patent number: 10624879
    Abstract: The present invention provides a physically and chemically stable pharmaceutical liquid composition including sodium picosulfate, magnesium oxide, citric acid and malic acid and methods of making and using such a composition.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: April 21, 2020
    Assignee: FERRING INTERNATIONAL CENTER S.A.
    Inventors: Bong Gil Nam, Byeung Jun Lee, Shunji Jin
  • Patent number: 10610522
    Abstract: The present invention provides new methods and kits for the retreatment of IBS.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: April 7, 2020
    Assignee: Salix Pharmaceuticals, Inc.
    Inventors: Pam Golden, Enoch Bortey, William Forbes, Craig Paterson
  • Patent number: 9827231
    Abstract: The present invention provides a physically and chemically stable pharmaceutical liquid composition including sodium picosulfate, magnesium oxide, citric acid and malic acid and methods of making and using such a composition.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: November 28, 2017
    Assignee: Ferring International Center S.A.
    Inventor: Bong Gil Nam
  • Patent number: 9393285
    Abstract: The present invention provides a pharmaceutical composition, and methods of use thereof, for treating ocular boundary deficiency, symptoms associated therewith, or undesired condition that is associated with or causes ocular boundary deficiency at the ocular surface. The pharmaceutical composition of the present invention comprises a human PRG4 protein, a lubricant fragment, homolog, or isoform thereof, suspended in an ophthalmically acceptable balanced salt solution. The pharmaceutical composition of the present invention may also comprise one or more ophthalmically acceptable agents selected from the group consisting of an ophthalmically acceptable demulcent, excipient, astringent, vasoconstrictor, emollient, sodium hyaluronate, hyaluronic acid, and surface active phospholipids, in a pharmaceutically acceptable carrier for topical administration.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: July 19, 2016
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SCHEPENS EYE RESEARCH INSTITUTE
    Inventors: Benjamin Sullivan, Tannin A. Schmidt, David A. Sullivan
  • Patent number: 9149493
    Abstract: The present invention relates to a dry composition for reconstitution in water comprising polyethylene glycol (PEG), optionally sodium sulphate, citric acid, sodium citrate, sodium chloride, potassium chloride, simethicone, effective for bowel cleansing, in particular of colon, prior to diagnostic, surgical or therapeutical procedures, in particular colonoscopy.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: October 6, 2015
    Assignee: ALFA WASSERMANN SPA
    Inventors: Alessandro Zanarotti, Gabriele Brunetti, Sergio Cecchetti
  • Publication number: 20150140117
    Abstract: The present invention generally relates to the field of bone substitute materials, and particularly to a bone substitute material that is bioactivated. More specifically, the present invention relates to a particular agent comprising citrate, citric acid, monobasic sodium phosphate, dextrose, and adenine for use in improving or promoting osseointegration of a bone substitute material, to a bone substitute material provided with a coating of said particular agent, and to a kit for use in a method of installing a bone substitute material comprising a bone substitute material as well as citrate, citric acid, monobasic sodium phosphate, dextrose, and adenine.
    Type: Application
    Filed: July 5, 2013
    Publication date: May 21, 2015
    Inventor: Günter Uhr
  • Publication number: 20150125544
    Abstract: A solid composition for treating cooling or heated water systems to remove scale, microorganisms and biofilm, and corrosion by-products. The composition for cooling towers and chilled water systems comprises chelating agents and an anionic surfactant. The composition for boilers and heated water systems comprises a sulfite, neutralizing amines, sodium phosphate, and, optionally, a polymethacrylate or polyacrylate polymer. A method for using such a treatment composition comprises contacting the treatment composition with substantially all parts of the water system.
    Type: Application
    Filed: November 4, 2014
    Publication date: May 7, 2015
    Inventors: Ecaterina Henderson, Pedro G. Gomez, John T. Buxton, Lyle H. Steimel
  • Publication number: 20150125543
    Abstract: A gel composition that includes: (i) sodium dihydrogen phosphate; (ii) LAPONITE® (sodium magnesium fluorosilicate); (iii) hypochlorous acid; and (iv) water. Also included are methods of manufacturing the gel composition, as well as methods of using the gel composition, e.g., contacting a topical surface of an animal (e.g., human) with the gel composition.
    Type: Application
    Filed: November 7, 2013
    Publication date: May 7, 2015
    Applicant: Simple Science Limited
    Inventors: Eoin Croke, Danielle Power
  • Patent number: 9017716
    Abstract: The present invention is directed to an ophthalmic lens integrally formed with a hydrogel, the hydrogel including a copolymer obtained from a composition containing (A) an ionic compound including a cation having a polymerizable functional group, and a fluorine-containing anion (hereinafter, referred to as (A) ionic compound), and (B) a hydrophilic compound having a polymerizable functional group.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: April 28, 2015
    Assignee: Menicon Co., Ltd.
    Inventor: Kohsuke Satake
  • Patent number: 9011931
    Abstract: A composition used to facilitate healing of cold sores, fever blisters and canker sore that includes potassium, rubidium, zinc, calcium and sodium is provided. This composition is compounded into a polyethylene glycol ointment containing allantoin (0.5 to 2 percent) and camphor (0.1 to 3 percent) and/or menthol (0.1 to 1 percent). In another embodiment, a method to treat cold sores, fever blisters and canker sores is provided by applying an effective amount of this composition to cold sores, fever blisters and canker sores of a subject in need of treatment thereof.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: April 21, 2015
    Inventors: Libby Robinson, Mikel Hays
  • Publication number: 20150064119
    Abstract: The invention relates to a cosmetic formulation comprising an additive agent. The additive agent having a water soluble linear alkali polyphosphate with a chain length of at least 4 to 50. The alkali polyphosphate exhibits complexing, dispersing, and antimicrobial effects. The alkali polyphosphate has a pH in the range of 6.5 to 8.5 (in aqueous solutions).
    Type: Application
    Filed: March 27, 2014
    Publication date: March 5, 2015
    Applicant: BK Giulini Chemie Gmbh
    Inventors: Thauern Henrike, Gabriele Brix, Thomas Staffel
  • Publication number: 20150030694
    Abstract: The present invention generally relates to formulations and methods for treating oral inflammation, oral injury and/or oral pain by applying hydrogel, viscous liquid, or other formulation to the oral cavity. Wet formulations comprise a hydrophilic polymer selected from the group consisting of pyrrolidones, hyaluronic acid and salts thereof, alginic acid and salts thereof, and carrageenans and salts thereof; calcium salts or ions, phosphate salts or ions, and water as well as other optional components. Dry formulations such as powders are also contemplated.
    Type: Application
    Filed: July 24, 2014
    Publication date: January 29, 2015
    Inventors: Edward D. Kobus, Bartholomew Weldon
  • Patent number: 8940319
    Abstract: The present invention is directed to compositions, devices, and methods for non-irritatively treating and preventing mucositis, such as chronic rhinosinusitis (CRS). Some aspects of the invention concern compositions comprising or consisting essentially of sodium phosphate buffer (e.g., sodium phosphate dibasic and sodium phosphate monobasic) and calcium carbonate; mucoadministration devices and kits containing such compositions; and methods for treating or preventing mucositis conditions such as CRS, comprising mucoadministering a composition of the invention to a subject in need thereof.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: January 27, 2015
    Assignee: Accentia Biopharmceuticals, Inc.
    Inventors: Francis E. O'Donnell, Angelos M. Stergiou
  • Publication number: 20140370117
    Abstract: The present invention provides an enteral nutritional composition with which the labor of administering water between meals can be saved. The enteral nutritional composition comprises proteins, carbohydrates and lipids, with the calories per ml of the composition being less than 1 kcal and the moisture content being 30 percent by mass or more.
    Type: Application
    Filed: June 24, 2014
    Publication date: December 18, 2014
    Applicant: NUTRI CO., LTD.
    Inventors: Susumu KAWAGUCHI, Yoshifumi INOUE
  • Patent number: 8859007
    Abstract: An improved composition for inducing bone growth is provided that is a mixture of DBM and a perfluorocarbon oxygen carrier. Injection/implantation of a composition of DBM and a perfluorocarbon results in enhancement of bone formation.
    Type: Grant
    Filed: January 13, 2013
    Date of Patent: October 14, 2014
    Assignee: Theracell, Inc.
    Inventors: Andrew J. Carter, Nelson L. Scarborough, Richard K. Grant, Frank M. Phillips, Stephen H. Hochschuler
  • Patent number: 8852561
    Abstract: Fluoride varnish compositions for temporary application and adhesion to a person's teeth. The composition includes a carrier comprising a resin and an adhesion promoting agent comprising an alkyl phosphoric acid. A fluoride ion source (e.g., a fluoride salt such as sodium fluoride) is dispersed within the carrier so as to provide biologically available fluoride ions to the tooth tissue being treated. The composition adheres only temporarily to tooth tissue (e.g., for a period of at least about 4 minutes, but not more than about 1 year), after which the composition spontaneously wears away as a natural result of the action of the tongue, saliva and/or other factors.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: October 7, 2014
    Assignee: Ultradent Products, Inc.
    Inventors: Jeff A. Wagner, Andy T. Kawamoto
  • Patent number: 8828449
    Abstract: The present invention provides a non-irritating, sprayable wound dressing composition and a non-irritating, non-sprayable ointment for treating wounds in mammals such as horses or dogs. The composition of the present invention is made of an acceptable carrier and an active ingredient made of organic salts of naturally occurring cations having the capacity to facilitate healing of wounds.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: September 9, 2014
    Inventors: Libby Robinson, Mikel Hays
  • Patent number: 8771749
    Abstract: The invention relates to a stable bicarbonate ion-containing drug solution, particularly a bicarbonate-containing drug solution for dialysis in which the stability has been improved by the presence of a phosphate ion. Further, the invention relates to a drug solution for acute blood purification, particularly a dialysate and a substitution liquid for acute blood purification to be mixed before use containing the drug solution. Still further, the invention relates to a dialysate and a substitution liquid for acute blood purification to be mixed before use in which the formation of insoluble fine particles or precipitates is prevented for a long time after mixing and with which hypokalemeia and hypophosphatemia are not caused.
    Type: Grant
    Filed: October 6, 2008
    Date of Patent: July 8, 2014
    Assignees: National University Corporation Chiba University, Fuso Pharmaceutical Industries, Ltd.
    Inventors: Shigeto Oda, Tomohito Sadahiro, Masataka Nakamura, Syuichi Tanaka, Shogo Tokuoka, Hiroya Otani
  • Publication number: 20140178492
    Abstract: The invention provides compositions for rapid bowel cleansing comprising a water-soluble mixture of polyethylene glycol and sodium phosphate(s). The compositions are particularly useful for preparing the bowel prior to surgery or diagnostic procedures such as colonoscopies. The invention further comprises methods for cleansing the bowel using these compositions, and bowels cleansing kits comprising these compositions.
    Type: Application
    Filed: December 21, 2012
    Publication date: June 26, 2014
    Inventor: GEORGE M. HALOW
  • Publication number: 20140140946
    Abstract: A method of preparing a cosmetic composition for external use with antibacterial and antifungal effects, the method including: providing a first composition comprising citric acid as an active ingredient in a first form; providing a second composition comprising trisodium phosphate as an active ingredient in a second form; and locally administering the first and second composition separately to a skin.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Inventors: Chung Hyun JUNG, Nam Woong YANG
  • Publication number: 20140134251
    Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.
    Type: Application
    Filed: October 23, 2013
    Publication date: May 15, 2014
    Applicant: PULMATRIX, INC.
    Inventors: Michael M. LIPP, Robert W. CLARKE, David L. HAVA, Richard BATYCKY, John HANRAHAN
  • Patent number: 8691291
    Abstract: A method for preparing the human bowel to undergo colonoscopy. A salt solution, preferable having a 0.9% w/v concentration of sodium chloride in water and warmed to 40 C. degrees, is utilized. A series of twisting and maneuvering exercises, such as those used in Yoga, is also performed. A predetermine quantity of the salt solution is consumed during predetermined intervals between the exercise steps, intending to clear and cleanse the colon so as to prepare it to undergo colonoscopy within about 3 to 24 hours after the completion of the preparation.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: April 8, 2014
    Assignee: Vikalp, Inc.
    Inventor: Vijay Arya
  • Patent number: 8691285
    Abstract: Methods of using a non-irritant, low pH acidic composition to destroy undesirable microorganisms are described. The methods may be used on food products, food processing equipment, and in aqueous solutions.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: April 8, 2014
    Assignee: CMS Innovative Technologies, Inc.
    Inventors: Barry Cummins, David Creasey
  • Publication number: 20140021202
    Abstract: An improved beverage can includes a GRAS antimicrobial wipe contained in a low profile pouch that is adhered to the side of the can. The low profile pouch is constructed of a substantially planar substrate that retains the wipe directly to the exterior surface of the can. The pouch includes a perforated tab that is removed to access the wipe. To use, the perforated tab is ripped off, the user reaches into the pouch and pulls out the antimicrobial wipe, and wipes the can as desired, typically focusing on the drinking region of the can.
    Type: Application
    Filed: July 5, 2013
    Publication date: January 23, 2014
    Inventor: CHRISTOPHER HANDS
  • Publication number: 20130302438
    Abstract: A process for producing aqueous chlorous acid solution in which chlorous acid, which is safe for the human body, is easy to handle, and less generates chlorine dioxide, is yielded and used as a disinfectant for a pretreatment in food processing. To an aqueous sodium chlorate solution is added sulfuric acid or an aqueous solution thereof in such an amount and concentration that the pH of the aqueous solution can be kept at 2.3-3.4 to thereby react them and generate chloric acid. Subsequently, hydrogen peroxide is added to the chloric acid in an amount which is equal to or larger than the amount necessary for a reduction reaction to thereby yield chlorous acid. Any one of inorganic acids, inorganic acid salts, organic acids, and organic acid salts, or two or more thereof, or a combination or these is added to the aqueous solution containing chlorous acid yielded, whereby the chlorous and acid can be present for long and the pH of the aqueous solution is regulated to regulated to 3.2-7.0.
    Type: Application
    Filed: April 15, 2013
    Publication date: November 14, 2013
    Inventor: Hisataka Goda
  • Patent number: 8574609
    Abstract: Broad spectrum disinfecting and microbicidal compositions of biodegradable and environmentally friendly compositions containing esters formed from fatty organic alcohols and fatty carboxylic acids. These compositions display activities against the most resistant microbial forms including bacterial spores. The preparations can be used in health care, food processing, personal care and other industries where the use of harsh oxidizing chemicals is undesirable.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: November 5, 2013
    Inventor: John Alex Lopes
  • Patent number: 8524635
    Abstract: The present invention relates to a process for the treatment of an agricultural product which comprises the addition of a composition which comprises phosphite and natamycin to the agricultural product wherein the composition comprises preferably less than 0.1 g lignosulphonate, more preferably less than 0.1 g polyphenol, per gram natamycin and is still more preferably free of lignosulphonate and most preferably free of polyphenol.
    Type: Grant
    Filed: July 16, 2007
    Date of Patent: September 3, 2013
    Assignees: DSM IP Assets B.V., Ceradis B.V.
    Inventors: Jacobus Stark, Ferdinand Theodorus Jozef Van Rijn, Wilhelmus Maria Van Der Krieken, Lucas Henricus Stevens
  • Patent number: 8507009
    Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: August 13, 2013
    Assignee: Salix Pharmaceuticals, Inc.
    Inventors: Stephen Skiendzielewski, Martin Rose, Ngoc Do
  • Publication number: 20130189203
    Abstract: The invention relates to a cosmetic additive agent with complexing, dispersing, and antimicrobial effects. The additive includes at least one linear alkali polyphosphate with a chain length of at least 3, such as a sodium or potassium polyphosphate. The invention also relates to a cosmetic preparation containing the additive.
    Type: Application
    Filed: February 27, 2012
    Publication date: July 25, 2013
    Applicant: BK Giulini GmbH
    Inventors: Thauern Henrike, Gabriele Brix, Thomas Staffel
  • Patent number: 8486424
    Abstract: One embodiment includes a method including boiling unsalted butter over low heat until it appears golden to form purified butter; cooling the purified butter by removing it from the heat; straining or filtering the purified butter; refrigerating the purified butter for at least 24 hours; thoroughly blending together the elements of an organic carrier medium, wherein the organic carrier medium comprises the purified butter, olive oil, and honey; adding distilled water to the blended organic carrier medium; mixing the distilled water and the blended organic carrier medium at high speed; and adding at least one of sodium acid pyrophosphate, cornstarch, bismuth subnitrate, salicylic acid, or alkali metal salicylates, and mixing.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: July 16, 2013
    Inventor: Radmila Stojkoski
  • Publication number: 20130171220
    Abstract: A bioactive glass composition comprising one or more glasses comprising Si02, P205 and a fluoride, the Si02 content being less than 40 mole %, the P205 content being at least 4 mole %, and the fluoride content being greater than 1 mole %. The bioactive glass or glass-ceramic can be used in a number of medical applications, including dental applications such as toothpaste.
    Type: Application
    Filed: June 24, 2011
    Publication date: July 4, 2013
    Inventors: Robert Hill, Delia Brauer, David G. Gilam, Natalia Karpukhina, Andrew Bushby, Mohammad Mneimne
  • Publication number: 20130164384
    Abstract: The present invention relates to formulations and kits for the treatment of bowel disease, to their use in medicinal preparations and to therapeutic methods thereof.
    Type: Application
    Filed: September 5, 2012
    Publication date: June 27, 2013
    Applicant: Salix Pharmaceuticals, Ltd.
    Inventors: Lorin Johnson, William Forbes, Stephana Patton
  • Publication number: 20130156864
    Abstract: The present invention relates to a cement based on magnesium sodium phosphate with clinical applications in bone surgery and odontology. This cement has an intrinsic antimicrobial effect as its main property. It also has a fast setting time, along with a high short-term compressive strength. Another property inherent to these cements is their adhesive character. Use of the cement is indicated for bone and dental applications, as well as filling bone defects or sealing dental cavities. The cement is especially indicated in cases in which an antimicrobial effect and/or adhesive properties are necessary.
    Type: Application
    Filed: March 11, 2011
    Publication date: June 20, 2013
    Applicant: Universitat Politecnica De Catalunya
    Inventors: Maria Pau Ginebra Molins, Gemma Mestres Beà
  • Publication number: 20130149391
    Abstract: Fluoride varnish compositions for temporary application and adhesion to a person's teeth. The composition includes a carrier comprising a resin and an adhesion promoting agent comprising an alkyl phosphoric acid. A fluoride ion source (e.g., a fluoride salt such as sodium fluoride) is dispersed within the carrier so as to provide biologically available fluoride ions to the tooth tissue being treated. The composition adheres only temporarily to tooth tissue (e.g., for a period of at least about 4 minutes, but not more than about 1 year), after which the composition spontaneously wears away as a natural result of the action of the tongue, saliva and/or other factors.
    Type: Application
    Filed: February 7, 2013
    Publication date: June 13, 2013
    Applicant: Ultradent Products, Inc.
    Inventor: Ultradent Products, Inc.
  • Publication number: 20130149390
    Abstract: The present invention provides methods for facilitating cleansing of the gastrointestinal tract of a patient prior to a diagnostic, surgical or therapeutic procedure. The methods can improve patient compliance, and thus, efficacy of the preparation. Specifically, the present methods make the gastrointestinal tract preparation composition palatable for the patient to consume. For example, for a patient preparing to undergo colonoscopy, the present methods make the bowel preparation solution taste significantly less salty.
    Type: Application
    Filed: December 7, 2012
    Publication date: June 13, 2013
    Applicant: MSM INNOVATIONS, INC.
    Inventor: MSM INNOVATIONS, INC.
  • Patent number: 8425944
    Abstract: A kit for colonic cleansing includes a phosphate salt laxative, a flavorant, and an oral rehydration mixture. The flavorant includes aspartame and a citrate, and the oral rehydration mixture includes sodium and a glucose containing saccharide. The kit may be used for a colonic cleansing procedure by combining the phosphate salt laxative and the flavorant to provide a flavored laxative liquid, orally administering to a subject the flavored laxative liquid, and orally administering to the subject an oral rehydration liquid.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: April 23, 2013
    Assignee: C. B. Fleet Company, Inc.
    Inventor: Michael L. Caswell
  • Publication number: 20130095183
    Abstract: The bone graft system comprises a solid inorganic component, which is bone graft material, and a hydrogel. The hydrogel contains >2 ppm of silicon ions, calculated as parts by weight of Si per million of the aqueous component of the hydrogel. Preferably, the solid inorganic component comprises hydroxyapatite or a silicon-containing hydroxyapatite, and may be a silicon-containing hydroxyapatite having a Ca/P ratio in the range 2.05 to 2.55 and a Ca/(P+Si) molar ratio less than 1.66. Bone healing is promoted by delivery of silicon ion release from the hydrogel and by the solid inorganic component stimulating cell behavior.
    Type: Application
    Filed: June 22, 2011
    Publication date: April 18, 2013
    Inventors: Iain Ronald Gibson, Janet Mabel Scott Skakle, Jordan Christopher Conway, Basil Annaz
  • Patent number: 8409622
    Abstract: A process for producing a biocompatible material includes the steps of mixing an extract of a fish scale-derived hydroxyapatite (with water content of 70 to 75% by weight) and of a fish scale-derived collagen (with water content of 40 to 60% by weight) in the weight percent ratio of about 8:2, stirring the mixture and drying the mixture by a hot blast in order to obtain a composite.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: April 2, 2013
    Assignee: RBS Co., Ltd.
    Inventor: Yoshiaki Okada
  • Publication number: 20130064872
    Abstract: The present invention relates to a skin preparation composition for external use with an excellent antibacterial effect, and more specifically, to a skin preparation composition for external use with excellent antibacterial and antifungal effects against bacteria and mold, comprising a first composition containing citric acid as an active ingredient and a second composition containing trisodium phosphate as an active ingredient.
    Type: Application
    Filed: May 20, 2010
    Publication date: March 14, 2013
    Inventors: Chung Hyun Jung, Nam Woong Yang
  • Patent number: 8383163
    Abstract: Fluoride varnish compositions for temporary application and adhesion to a person's teeth. The composition includes a carrier comprising a resin and an adhesion promoting agent comprising an alkyl phosphoric acid. A fluoride ion source (e.g., a fluoride salt such as sodium fluoride) is dispersed within the carrier so as to provide biologically available fluoride ions to the tooth tissue being treated. The composition adheres only temporarily to tooth tissue (e.g., for a period of at least about 4 minutes, but not more than about 1 year), after which the composition spontaneously wears away as a natural result of the action of the tongue, saliva and/or other factors.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: February 26, 2013
    Assignee: Ultradent Products, Inc.
    Inventors: Jeff A. Wagner, Andy T. Kawamoto
  • Publication number: 20130039994
    Abstract: A method of colonic cleansing that includes administering orally a first dose and a second dose of a liquid osmotic colonic evacuant composition. The second dose includes an amount of the liquid osmotic colonic evacuant composition that is 55% to 95% of the amount of the first dose.
    Type: Application
    Filed: August 20, 2012
    Publication date: February 14, 2013
    Inventor: Michael L. Caswell
  • Patent number: 8361452
    Abstract: The invention provides a method for rapid bowel cleansing which includes the use of a mixture of polyethylene glycol and sodium phosphate(s). The method is particularly useful for preparing the bowel prior to surgery or diagnostic procedures such as colonoscopies. The invention further comprises methods for cleansing the bowel using these compositions, and bowel cleansing kits comprising these compositions.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: January 29, 2013
    Inventor: George M. Halow
  • Publication number: 20120288569
    Abstract: Phosphate depletion, a physiological condition commonly seen in certain patient populations, including alcoholics, malnourished, acutely ill patients, patients receiving parenteral nutrition, patients being re-fed after prolong fasting, and dialysis patients, requires intravenous supplementation when oral repletion is not feasible. This invention provides a method and pharmaceutical composition for therapeutic administration of pyrophosphate, instead of phosphate, for phosphate or pyrophosphate repletion. During hemodialysis or peritoneal dialysis significant removal of phosphate and pyrophosphate occurs. Pyrophosphate depletion predisposes patients to vascular calcification. This invention further provides a method and pharmaceutical composition for therapeutic administration of pyrophosphate for phosphate or pyrophosphate repletion by addition of pyrophosphate to hemodialysis or peritoneal dialysis solutions.
    Type: Application
    Filed: May 22, 2012
    Publication date: November 15, 2012
    Inventor: Ajay Gupta
  • Patent number: 8263136
    Abstract: A method of colonic cleansing that includes administering orally a first dose and a second dose of a liquid osmotic colonic evacuant composition. The second dose includes an amount of the liquid osmotic colonic evacuant composition that is 55% to 95% of the amount of the first dose.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: September 11, 2012
    Assignee: C.B. Fleet Company Inc.
    Inventor: Michael L. Caswell
  • Patent number: 8241671
    Abstract: In order to provide a biocompatible material consisting mainly of a fish scale-derived hydroxyapatite and a fish scale-derived collagen, which is adjusted so that easily digested and absorbed in a human body, the material contains a composite consisting mainly of a fish scale-derived hydroxyapatite and a fish scale-derived collagen.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: August 14, 2012
    Assignee: RBS Co., Inc.
    Inventor: Yoshiaki Okada
  • Patent number: 8241416
    Abstract: To provide an inorganic waterborne coating agent and its aqueous solution: wherein, with the surface of the base material highly-hydrophilizated, the contaminant such as oil-based contaminant and inorganic dust adhered onto the surface of the base material can be removed easily with water, and at the same time, the antistatic effect can be achieved due to its dust-repelling property; which can be applied by anyone (non-skilled) with ease without considering the base material being organic or inorganic, compared with conventional coating agents, such as photocatalyst and polysilazane-based glass coating agent that have limited range of use; and which has little limit in conditions of use, and is inexpensive and applicable to any places, thereby securing the original goal of antifouling property. To provide an inorganic waterborne coating agent comprising: alkaline colloidal silica, a sodium phosphate compound and a potassium phosphate mixture, and boric acid.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: August 14, 2012
    Assignee: Trade Service Corporation
    Inventor: Katsumi Kishimoto
  • Publication number: 20120189709
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 26, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Publication number: 20120177744
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 12, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Patent number: 8216172
    Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolytes but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: July 10, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Peter C. Chang, Jean-Michel Lannoy