Sodium Containing Or Fluorine Containing Patents (Class 424/606)
  • Patent number: 8241416
    Abstract: To provide an inorganic waterborne coating agent and its aqueous solution: wherein, with the surface of the base material highly-hydrophilizated, the contaminant such as oil-based contaminant and inorganic dust adhered onto the surface of the base material can be removed easily with water, and at the same time, the antistatic effect can be achieved due to its dust-repelling property; which can be applied by anyone (non-skilled) with ease without considering the base material being organic or inorganic, compared with conventional coating agents, such as photocatalyst and polysilazane-based glass coating agent that have limited range of use; and which has little limit in conditions of use, and is inexpensive and applicable to any places, thereby securing the original goal of antifouling property. To provide an inorganic waterborne coating agent comprising: alkaline colloidal silica, a sodium phosphate compound and a potassium phosphate mixture, and boric acid.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: August 14, 2012
    Assignee: Trade Service Corporation
    Inventor: Katsumi Kishimoto
  • Publication number: 20120189709
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 26, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Publication number: 20120177744
    Abstract: Disclosed are methods of treating an individual having a condition characterized by an imbalance in type 1 and type 2 cytokine production, wherein the method comprises administering to the individual an amount of ?-hydroxy-?-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type 1 to type 2 cytokines, including an increase in the ratio of type 1 to type 2 cytokines without a corresponding increase in type 2 cytokine levels. Also disclosed are methods of using HMB to treat asthma and allergies. The methods of the present invention are based upon the discovery that HMB modulates cytokine production, most typically by increasing type 1 cytokines without a corresponding increase in type 2 cytokines.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 12, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Debra L. Thomas, Pradip Mukerji
  • Patent number: 8216172
    Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolytes but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: July 10, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Peter C. Chang, Jean-Michel Lannoy
  • Publication number: 20120164219
    Abstract: To provide a peroral tablet for bowel cleansing which leaves no remains in the intestinal tract after bowel cleansing, which exhibits a dissolution property equivalent to that of conventional sodium phosphate-containing tablets including crystalline cellulose, and which is a small-size agent readily taken by a subject. The peroral tablet for bowel cleansing containing the following ingredients (A) and (B): (A) 80 to 95 mass % of sodium phosphate, and (B) (B1) 7 to 11 mass % of hydroxypropyl cellulose which has such a particle size that ?99% of the particles thereof pass through a mesh having an opening of 350 ?m and whose 2-mass % aqueous solution has a viscosity of 2.0 to 10.0 mPa·s, (B2) 5 to 13 mass % of hydroxypropyl cellulose which has such a particle size that ?99% of the particles thereof pass through a mesh having an opening of 150 ?m and whose 2-mass % aqueous solution has a viscosity of 3.0 to 5.
    Type: Application
    Filed: August 27, 2010
    Publication date: June 28, 2012
    Applicant: ZERIA PHARMACEUTICAL CO., LTD.
    Inventors: Masafumi Nomura, Tetsuyuki Nishiyama, Mari Ichikawa, Kyoko Fukaya
  • Publication number: 20120156308
    Abstract: The present application discloses a fast-setting mineral trioxide aggregate (MTA) with fluoride release for practical treatment of diseases in teeth and bone, e.g. for caries treatment and/or prevention. The cariostatic MTA contain calcia-silica-alumina cement with moderately increased tricalcium aluminate content allowing high calcium hydroxide release. The MTA composition support remineralization and biomineralization, and it is suitable for stimulation of hard tissue regeneration. MTA embodiments contain superplasticizerand nanosilicate for improved mechanical properties. The MTA compositions include optional radiocontrast and nano-enriched leachable fluorine, nitrate, strontium, and phosphate. The fast-setting MTA paste exhibits flow-to-clay-like consistency, which allows new practical applications including cavity lining, temporary restoration, bonding, and cementations in one MTA embodiment.
    Type: Application
    Filed: August 27, 2010
    Publication date: June 21, 2012
    Applicant: Dentosolve
    Inventors: Henrik Lovschall, Pia Kjaergaard, Jesper Thorsen
  • Publication number: 20120107414
    Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.
    Type: Application
    Filed: March 26, 2010
    Publication date: May 3, 2012
    Applicant: Pulmatrix, Inc.
    Inventors: Michael M. Lipp, Robert W. Clarke, David L. Hava, Richard Batycky, John Hanrahan
  • Patent number: 8158157
    Abstract: A multi-part substitution infusion fluid for an extracorporeal blood treatment and methods for using same are provided. Generally, the multi-part substitution fluid comprises a first solution composed of electrolites but without divalent cations and a second solution comprising divalent cations. Another embodiment includes a third solution comprising a matching citrate/citric acid anticoagulant. The described methods of using the multi-part substitution infusion fluids significantly reduce risks associated with various extracorporeal blood treatments.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: April 17, 2012
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Peter C. Chang, Jean-Michael Lannoy
  • Publication number: 20120021064
    Abstract: The present invention relates to formulations and kits for gastrointestinal cleansing and to therapeutic methods thereof.
    Type: Application
    Filed: September 27, 2011
    Publication date: January 26, 2012
    Applicant: Salix Pharmaceuticals, Ltd.
    Inventor: Stephana Patton
  • Publication number: 20120009273
    Abstract: An array of pharmaceutical formulations characterized by the presence of molecular oxygen comprising four elements which, in combination, furnish benefits for the health of patients with HIV AIDS: (i) weight increase of the patient; (ii) increase of appetite; (iii) reduction of diarrhea; (iv) reduction of the wasting syndrome; (v) increase of stability of mood; (vi) increase of muscular mass. (vii) decrease of opportunistic diseases, in particular infections caused by Candida, herpes virus, cytomegalovirus, Kaposi's sarcoma; (viii) prolongation of the period wherein the patient does not require to take antiretrovirals; (ix) increase of acceptance of pharmacological treatment; x. reduction of gastritis, nausea or vomiting, headache; (xi) reduction of cases with anemia or thrombocytopenia; and (xii) a change in the phase of the disease in the patient.
    Type: Application
    Filed: May 10, 2011
    Publication date: January 12, 2012
    Inventor: David IZQUIERDO ALCALDE
  • Publication number: 20110308988
    Abstract: A method of colonic cleansing that includes administering orally a first dose and a second dose of a liquid osmotic colonic evacuant composition. The second dose includes an amount of the liquid osmotic colonic evacuant composition that is 55% to 95% of the amount of the first dose.
    Type: Application
    Filed: August 12, 2011
    Publication date: December 22, 2011
    Inventor: Michael L. Caswell
  • Publication number: 20110274765
    Abstract: A kit for colonic cleansing includes a phosphate salt laxative, a flavorant, and an oral rehydration mixture. The flavorant includes aspartame and a citrate, and the oral rehydration mixture includes sodium and a glucose containing saccharide. The kit may be used for a colonic cleansing procedure by combining the phosphate salt laxative and the flavorant to provide a flavored laxative liquid, orally administering to a subject the flavored laxative liquid, and orally administering to the subject an oral rehydration liquid.
    Type: Application
    Filed: July 15, 2011
    Publication date: November 10, 2011
    Inventor: Michael L. Caswell
  • Publication number: 20110274764
    Abstract: A kit for colonic cleansing includes a phosphate salt laxative, a flavorant, and an oral rehydration mixture. The flavorant includes aspartame and a citrate, and the oral rehydration mixture includes sodium and a glucose containing saccharide. The kit may be used for a colonic cleansing procedure by combining the phosphate salt laxative and the flavorant to provide a flavored laxative liquid, orally administering to a subject the flavored laxative liquid, and orally administering to the subject an oral rehydration liquid.
    Type: Application
    Filed: July 15, 2011
    Publication date: November 10, 2011
    Inventor: Michael L. Caswell
  • Publication number: 20110268782
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Application
    Filed: July 13, 2011
    Publication date: November 3, 2011
    Applicant: WARSAW ORTHOPEDIC, INC.
    Inventors: David Knaack, John Winterbottom, David Kaes, Todd Boyce, Lawrence A. Shimp
  • Publication number: 20110244055
    Abstract: The present invention relates to a method of suppressing appetite or promoting a stimulant effect in an individual in need thereof, comprising administering to the individual per 24 hour period an effective amount of one or more alkali metals selected from the group consisting of one or more sources of cesium, one or more sources of rubidium, one or more sources of lithium, and combinations thereof. The present invention further relates to weight loss or stimulant compositions comprising one or more alkali metals.
    Type: Application
    Filed: March 30, 2011
    Publication date: October 6, 2011
    Inventor: Arnold Forbes
  • Patent number: 8012511
    Abstract: A composition of matter and the method of making that provide a low pH acidic composition that is useful for destroying microorganisms that are undesirable and useful for destroying or reducing melanoma on human skin. The composition and method include a strong, low pH acid combined with distilled water and urea or an ammonium compound, such as ammonium sulfate or other metallic sulfates, including but not limited to, sodium sulfate, magnesium sulfate, zinc sulfate, manganese sulfate, and copper sulfate, under at least 15 psi pressure in pressurized container, all of which is heated to approximately 800° F. or more for at least 3 hours. The final cooled mixture is stabilized with 10 to 15 percent of the original mixture. The resultant composition is useful for preserving food, such as fresh fish, and for skin treatment of melanoma and as bactericides, fungicides, or viricides.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: September 6, 2011
    Assignee: Contact Marketing Solutions, LLC
    Inventors: Barry W. Cummins, David H. Creasey
  • Patent number: 7998510
    Abstract: A method of colonic cleansing that includes administering orally a first dose and a second dose of a liquid osmotic colonic evacuant composition. The second dose includes an amount of the liquid osmotic colonic evacuant composition that is 55% to 95% of the amount of the first dose.
    Type: Grant
    Filed: August 15, 2007
    Date of Patent: August 16, 2011
    Assignee: C. B. Fleet Company, Inc.
    Inventor: Michael L. Caswell
  • Patent number: 7985429
    Abstract: A kit for colonic cleansing includes a phosphate salt laxative, a flavorant, and an oral rehydration mixture. The flavorant includes aspartame and a citrate, and the oral rehydration mixture includes sodium and a glucose containing saccharide. The kit may be used for a colonic cleansing procedure by combining the phosphate salt laxative and the flavorant to provide a flavored laxative liquid, orally administering to a subject the flavored laxative liquid, and orally administering to the subject an oral rehydration liquid.
    Type: Grant
    Filed: March 1, 2007
    Date of Patent: July 26, 2011
    Assignee: C. B. Fleet Company, Inc.
    Inventor: Michael L. Caswell
  • Publication number: 20110117208
    Abstract: The invention provides the use of an unbound polyphosphate to promote chronic wound healing, in which the polyphosphate has at least 3 phosphate units. Also provided are a method of treatment and a pharmaceutical composition, both based on the use of the polyphosphate.
    Type: Application
    Filed: February 23, 2009
    Publication date: May 19, 2011
    Applicant: TECHNOSTICS LIMITED
    Inventors: Johnathan Craig Richardson, Peter William Dettmar, Rebecca Louise Allen, Cathal Padraig Coyle
  • Patent number: 7910090
    Abstract: The present invention provides a base composition that allows for the formulation of non-irritating cosmetic and/or dermatological compositions. The base composition includes one or more of electrolyte, buffer, mild preservative, lubricant, or any combinations thereof. It is preferred that one or more of the above components are eye-safe and/or eye-compatible. The present invention also provides photoprotective cosmetic and/or dermatological compositions that include the base composition and one or more sunscreen active components and are non-irritating to mammalian eyes.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: March 22, 2011
    Assignee: Playtex Products, Inc.
    Inventors: Olga V. Dueva-Koganov, James P. SaNogueira
  • Publication number: 20110066117
    Abstract: An enema comprises a bottle, and at least 150 ml of a solution in the bottle. The solution comprises water, 5.00 to 8.00 grams dibasic sodium phosphate, and 15.00 to 21.00 grams monobasic sodium phosphate.
    Type: Application
    Filed: November 23, 2010
    Publication date: March 17, 2011
    Inventors: Sarah S. Post, Michael L. Caswell, Charles H. Cox
  • Publication number: 20110052713
    Abstract: The present application relates to reduction of acrolein-mediated cell death following neural insult. According to at least one embodiment, chitosan is utilized as a membrane fusogen to restore cell function. According to at least one other embodiment, chitosan or silica is used to create a non-toxic polymer surfaced microcolloid (PSM). PSMs were found to preferentially target the damaged nerve tissues; to restore conduction of nerve impulses; to seal/restore nerve fiber membranes; and to reduce to baseline the efflux of a large intracellular enzyme. PSMs are further used as a drug delivery vehicle for acrolein scavengers including hydralazine.
    Type: Application
    Filed: January 16, 2009
    Publication date: March 3, 2011
    Inventors: Youngnam Cho, Riyi Shi, Albena Ivanslevic, Richard Borgens
  • Patent number: 7867521
    Abstract: The present invention provides compositions, kits, and methods suitable for cleansing the colon before colonoscopy. The compositions include a phosphate salt and a flavorant that includes aspartame and a citrate. The kits include the previously mentioned compositions and also may include suitable containers, packaging, relief wipes, and instructions for use. The methods may include administering orally to a subject an aqueous preparation including monobasic sodium phosphate, dibasic sodium phosphate, aspartame, and citric acid.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: January 11, 2011
    Assignee: C.B. Fleet Company, Incorporated
    Inventors: Nelson Ayala, Michael L. Caswell, Sarah S. Post, Sherrie Scott
  • Patent number: 7858124
    Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: December 28, 2010
    Assignee: Well-Being Biochemical Corp.
    Inventors: Jih Ru Hwu, Shwu Chen Tsay
  • Publication number: 20100316726
    Abstract: The invention provides a method of treating sensitive teeth comprising attaching a sealant composition comprising a basic amino acid to a person's tooth and allowing the basic amino acid to be slowly released over time in order to reduce chrome and/or acute tooth sensitivity together with compositions and methods of use.
    Type: Application
    Filed: February 6, 2009
    Publication date: December 16, 2010
    Applicant: COLGATE-PALMOLIVE COMPANY
    Inventors: Michael Prencipe, Belle Mead Scott Robinson, Rajnish Kohli, Richard J. Sullivan
  • Publication number: 20100278935
    Abstract: Compositions and methods for treating and/or preventing a medical condition are provided. For example, in one aspect the present invention provides a composition for treating or preventing a medical condition in a subject. Such a composition may include a sodium phosphate compound, an ammonium compound, and a silicate compound. Such a composition may be formulated for a variety of administrations modes, including, without limitation, oral, intramuscular, intravenous, transdermal, buccal, etc.
    Type: Application
    Filed: July 30, 2008
    Publication date: November 4, 2010
    Inventor: William C. Stacey
  • Patent number: 7799572
    Abstract: According to an aspect of the invention, a polymerized form of formaldehyde is available in granular form containing a polymerized form of formaldehyde, such as paraformaldehyde, a buffer, such as sodium phosphate dibasic anhydrous, and a stabilizer, such as hydroxymethyl cellulose, or hydroxypropyl methyl cellulose. When added to an aqueous solvent, the paraformaldehyde can dissolve in alkaline solution, and depolymerizes into a formaldehyde solution containing a stabilizer. Optionally a second member of the buffer pair or another buffer or pH adjuster can be used The stabilized depolymerized formaldehyde solution is then ready for use, or can be modified by addition of other substances, such as sodium phosphate monobasic monohydrate. Additionally, an additional buffer may be included in the granular mixture to increase the rate at which the solid dissolves and depolymerizes.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: September 21, 2010
    Inventor: James L Biesecker
  • Publication number: 20100209532
    Abstract: A method of delivering oxygen to a tissue, a blood vessel, an organ, or a region of an organ, under an ischemic condition, or prophylactically preventing occurrence of an ischemic condition, of a subject, comprising the step of administering to the subject an oxygenated hemoglobin solution, wherein the oxygenated hemoglobin solution includes polymerized hemoglobin, and wherein about 80% by weight, or greater, of the polymerized hemoglobin is oxyhemoglobin.
    Type: Application
    Filed: June 13, 2008
    Publication date: August 19, 2010
    Applicant: OPK BIOTECH LLC
    Inventors: Gregory P. Dube, Zafiris W. Zafirelis, Anthony J. Laccetti, Javed Baqai
  • Publication number: 20100183736
    Abstract: The present invention relates to a composition for the relief of hangover symptoms and methods of treating hangover symptoms.
    Type: Application
    Filed: August 8, 2007
    Publication date: July 22, 2010
    Inventor: Evan Hays
  • Publication number: 20100159026
    Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.
    Type: Application
    Filed: January 20, 2010
    Publication date: June 24, 2010
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: Stephen Skiendzielewski, Martin Rose, Ngoc Do
  • Publication number: 20100136133
    Abstract: The invention provides intradialytic parenteral nutrition (IDPN) solutions with low carbohydrate for the treatment of malnutrition in dialysis patients. The IDPN solutions of the invention are particularly advantageous for the treatment of malnutrition in patients who are diabetic or suffer from other glucose management related pathologies or patients who require strict fluid management.
    Type: Application
    Filed: July 7, 2009
    Publication date: June 3, 2010
    Inventors: Eileen Moore, Stan Lindenfeld, Michelle Ricker
  • Patent number: 7718197
    Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: May 18, 2010
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Stephen Skiendzielewski, Martin Rose, Ngoc Do
  • Patent number: 7687075
    Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.
    Type: Grant
    Filed: November 16, 2004
    Date of Patent: March 30, 2010
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Stephen Skiendzielewski, Martin Rose, Ngoc Do
  • Publication number: 20090324736
    Abstract: The present invention relates to formulations and kits for the treatment of bowel disease, to their use in medicinal preparations and to therapeutic methods thereof.
    Type: Application
    Filed: May 7, 2009
    Publication date: December 31, 2009
    Applicant: Salix Pharmaceuticals, Ltd.
    Inventors: Lorin Johnson, William Forbes, Stephana Patton
  • Publication number: 20090297623
    Abstract: The present invention is directed to compositions, devices, and methods for non-irritatively treating and preventing mucositis, such as chronic rhinosinusitis (CRS). Some aspects of the invention concern compositions comprising or consisting essentially of sodium phosphate buffer (e.g., sodium phosphate dibasic and sodium phosphate monobasic) and calcium carbonate; mucoadministration devices and kits containing such compositions; and methods for treating or preventing mucositis conditions such as CRS, comprising mucoadministering a composition of the invention to a subject in need thereof.
    Type: Application
    Filed: August 3, 2009
    Publication date: December 3, 2009
    Applicant: ACCENTIA BIOPHARMACEUTICALS, INC
    Inventors: FRANCIS E. O'DONNELL, JR., ANGELOS M. STERGIOU
  • Publication number: 20090191279
    Abstract: Fluoride varnish compositions for temporary application and adhesion to a person's teeth. The composition includes a carrier comprising a resin and an adhesion promoting agent comprising an alkyl phosphoric acid. A fluoride ion source (e.g., a fluoride salt such as sodium fluoride) is dispersed within the carrier so as to provide biologically available fluoride ions to the tooth tissue being treated. The composition adheres only temporarily to tooth tissue (e.g., for a period of at least about 4 minutes, but not more than about 1 year), after which the composition spontaneously wears away as a natural result of the action of the tongue, saliva and/or other factors.
    Type: Application
    Filed: December 19, 2008
    Publication date: July 30, 2009
    Applicant: Ultradent Products, Inc.
    Inventors: Gordon R. Kennard, Jeff A. Wagner, Andy T. Kawamoto
  • Patent number: 7563460
    Abstract: A treatment protocol by which a renal stone patient is administered a chelating agent, generally once a day and preferably by mouth, during a treatment phase and is later administered the same chelating agent once a week, during a “maintenance” phase. The chelating agent is most preferably ethylene diamine tetraacetic acid (EDTA) and may be provided in a dosage form having an enteric coating and at least one external cathode and at least one external anode to create a galvanic current upon contact of the dosage form with the patient's intestinal contents.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: July 21, 2009
    Assignee: Med Five, Inc.
    Inventors: Alec D. Keith, William E. Crisp
  • Publication number: 20090142410
    Abstract: The present invention relates to the composition of a dietary supplement provided for increasing Creatine uptake and retention in skeletal muscle, increasing muscle mass and strength, increasing exercise capacity and aiding in recovery following exercise as well as supporting the immune system during periods of intense training. A method for achieving the same is also provided. The present invention comprises at least Creatine or derivatives thereof, Taurine or derivatives thereof and a source of Phosphate. The dietary supplement may further comprise one or more of the following: Double Fermented Triticum aestivum, Dextrose, Isomalt, Trehalose, D-Mannose, Mulberry extract, Enicostemma littorale Blume, Scoparia dulcis, Tarragon extract, Andrographis paniculata, Chromium or derivatives thereof, Glutamine and Alpha Lipoic Acid.
    Type: Application
    Filed: November 10, 2008
    Publication date: June 4, 2009
    Inventors: Marvin A. Heuer, Kenneth Clement, Shan Chaudhuri, James D. Ramsbottom, Megan K. Thomas
  • Publication number: 20090130223
    Abstract: The development relates to cosmetic and dermatological preparations containing aquaporin stimulators, in particular glyceryl glycosides, and their use to improve the moisturizing of the skin.
    Type: Application
    Filed: March 28, 2007
    Publication date: May 21, 2009
    Inventors: Ute Breitenbach, Wilfried Siefken, Tanja Delekat, Lara Terstegen, Helga Biergiesser, Franz Staeb, Gunja Springmann
  • Publication number: 20090105537
    Abstract: A device, a system and a method for in-vivo examination. A method for in-vivo examination includes substantially emptying a subject's colon from content, and inserting an autonomous in-vivo imaging device into the subject's gastrointestinal tract. An in-vivo examination kit includes an autonomous in-vivo imaging device, a wireless receiver, an antenna set, a laxative, and optionally a stimulant and an instructions leaflet.
    Type: Application
    Filed: January 1, 2006
    Publication date: April 23, 2009
    Inventors: Daniel Gat, Raphael Rabinovitz, Sharon Bonfis
  • Publication number: 20080299076
    Abstract: The present invention relates to erastin analogs, particularly compounds of formulae I and II, including compounds 1-20, 22-24, 34, and 40. The invention also relates to pharmaceutical compositions containing such analogs and to methods of treating conditions in a mammal with such analogs and pharmaceutical compositions.
    Type: Application
    Filed: February 28, 2008
    Publication date: December 4, 2008
    Inventor: Brent R. Stockwell
  • Publication number: 20080279820
    Abstract: The present invention provides compositions and methods for treating burns comprising administering to a burn area of a subject in need thereof of a therapeutically effective amount of a composition comprising an anti-cytokine or anti-inflammatory agent or a functional derivative thereof, and a pharmaceutically acceptable excipient.
    Type: Application
    Filed: April 11, 2008
    Publication date: November 13, 2008
    Inventors: Terry Lee HICKS, Jeffrey KOHUTKA
  • Publication number: 20080248128
    Abstract: The present application relates to a combination for treating fruit or vegetables comprising phosphorous acid (PA) and eugenol.
    Type: Application
    Filed: June 13, 2008
    Publication date: October 9, 2008
    Inventor: Alberto Sardo
  • Publication number: 20080220087
    Abstract: A composition and method for cleansing a colon prior to endoscopic procedure. More particularly, a combination of bisacodyl, metoclopramide, sodium, and/or a phosphorus containing composition administered in sequential doses for preparing a colon prior to colonoscopy.
    Type: Application
    Filed: February 6, 2008
    Publication date: September 11, 2008
    Inventor: Semaan Abboud
  • Publication number: 20080213393
    Abstract: This invention relates to novel colonic purgative compositions in a solid dosage form, comprising at least one purgative and at least one soluble, or soluble, nonfermentable binder, such as polyethylene glycol. Further, this invention relates to methods of using the colonic purgative compositions. The present compositions and methods are designed to improve patient tolerance and compliance, while at the same time improving the quality of bowel cleansing. The formulations and methods of this invention are particularly useful to cleanse the bowel prior to diagnostic and surgical procedures and can also be employed in lower dosages as a laxative to promote elimination and/or to relieve constipation.
    Type: Application
    Filed: March 13, 2008
    Publication date: September 4, 2008
    Applicant: Salix Pharmaceuticals, Inc.
    Inventors: Stephen Skiendzielewski, Martin Rose, Ngoc Do
  • Patent number: 7419680
    Abstract: Compositions useful in the prevention and treatment of osteoporosis and for bone and fracture repair. Slow-releasing calcium phosphate-based materials are disclosed, incorporating Mg, Zn, F and carbonate, which will promote bone formation and inhibit bone resorption and thus be agents for the cited uses.
    Type: Grant
    Filed: September 28, 2004
    Date of Patent: September 2, 2008
    Assignee: New York University
    Inventor: Racquel Z. LeGeros
  • Publication number: 20080119859
    Abstract: The present invention relates to a multi-purpose bio-material useful as a bone filler, bio-adhesive, bone cement and bone graft. One preferred embodiment of the present invention generally comprises: potassium phosphate, a metal oxide (i.e. MgO), a calcium containing compound, a sugar and an aqueous solution. Exemplary calcium containing compounds include but are not limited to tri-calcium phosphates. The present invention is particularly useful as a bio-adhesive for bone, ligament, and other soft tissue and has surprising and unexpected osteoproliferative effects. The composition can be used for a variety of other uses.
    Type: Application
    Filed: January 12, 2006
    Publication date: May 22, 2008
    Inventor: Thomas J. Lally
  • Patent number: 7335664
    Abstract: A composition and method for cleansing a colon prior to endoscopic procedure. More particularly, a combination of bisacodyl, metoclopramide, sodium, and/or a phosphorus containing composition administered in sequential doses for preparing a colon prior to colonoscopy.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: February 26, 2008
    Inventor: Semaan Abboud
  • Publication number: 20080044489
    Abstract: A method of colonic cleansing that includes administering orally a first dose and a second dose of a liquid osmotic colonic evacuant composition. The second dose includes an amount of the liquid osmotic colonic evacuant composition that is 55% to 95% of the amount of the first dose.
    Type: Application
    Filed: August 15, 2007
    Publication date: February 21, 2008
    Inventor: Michael L. Caswell
  • Patent number: RE42394
    Abstract: Fungicidal compositions for the protection of turfgrass against crown and root rot are disclosed. The compositions comprise, as the active material, (a) a first active agent selected from the group consisting of (i) a monoester salt of a phosphorous acid (preferably aluminum ethyl phosphite), and (ii) phosphorous acid or an alkali or alkali earth metal salt thereof; and (b) a benzoporphyrin compound. Preferred compositions comprise 1 part by weight of the first active agent, and between about 0.01 and about 0.1 parts by weight of the benzoporphyrin compound.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: May 24, 2011
    Assignee: Bayer CropScience Inc.
    Inventor: Laurence C. Mudge