Abstract: An antibacterial agent of the present invention contains a metal-containing compound containing a metal other than aluminum, and a phosphorus-adsorbing material. A method of using an antibacterial agent of the present invention is a method for improving an antibacterial property of a metal-containing compound containing a metal other than aluminum, wherein the metal-containing compound and a phosphorus-adsorbing compound are used in combination. Thus, the present invention provides an antibacterial agent, and a method of using an antibacterial agent, wherein an antibacterial property of a metal-containing compound containing a metal other than aluminum, particularly a silver-containing compound, is improved significantly.

Abstract: The invention relates to a domestic appliance, such as an iron, provided with a surface layer. The surface layer comprises an antimicrobial agent associated with a carrier, the carrier being inorganic and selected such that the antimicrobial activity of the surface layer according to JIS Z2801:2000 has a value of at least 2 after 100 hours of continuous use at a temperature of at least 230° C. In a preferred embodiment, the carrier is selected from the group consisting of a phosphate and a soluble silicate, while the antimicrobial agent is preferably selected from a group comprising ions of silver, zinc, copper, selenium, platinum or a combination thereof. The appliance stays fresher for a longer period of time than known hitherto. The invention further relates to an iron, a steam ironing device and a method of manufacturing the appliance.

Abstract: An antibacterial alloy coating composition is applied to a surface of a device. The composition comprises an antibacterial material and an alloy. The alloy consists of more than four metallic elements and at least one non-metallic element. The antibacterial material is, for example, copper, silver, or a combination thereof, and the atomic percentage content thereof is 1.7% to 26.8% of the total content. These metallic elements are selected from the group consisting of iron, cobalt, chromium, nickel, aluminum, vanadium, and titanium. The non-metallic element is selected from the group consisting of boron, oxygen, and nitrogen.

Abstract: Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator.

Abstract: A dressing composition for use as a skin dressing comprises an elastomeric-adhesive composition, and a zeolite comprising releasably adsorbed nitric oxide. The zeolite may comprise a transition metal cation such as Co, Fe, Mn, Ni, Cu, Zn, Ag or a mixture thereof as an extra-framework metal cation, preferably Zn. The elastomeric adhesive composition may be a hydrocolloid-adhesive composition comprising, hydrocolloid and elastomer. The dressing composition releases nitric oxide, which may have beneficial effects, when used on wounds or moist skin, with a substantially constant release rate over a long period of time. A dressing including a layer of the dressing composition has a backing layer and may have a release liner removably attached to the skin-contacting surface of the dressing layer.

Abstract: Structures treated with a microbiological interception enhancing agent comprising of a water-soluble cationic material having a counter ion associated therewith at specific sites on the cationic material, in combination with a biologically active metal salt, wherein the counter ion associated with the cationic material preferentially precipitates with at least a portion of the cation of the biologically active metal salt such that precipitation of the biologically active metal cation and the counter ion associated with the cationic material occurs in proximity to the cationic material are disclosed herein. The microbiological interception enhancing agent may be incorporated into articles of commerce by treating the starting materials of the structure or by applying the microbiological interception enhancing agent on to at least one surface of the article.

Abstract: We disclose a colorless composition comprising metal particles (e.g., silver nanoparticles) and water, wherein said particles comprise an interior of elemental metal (e.g., silver) and an exterior of metal oxide (e.g., one or more silver oxide(s)), wherein the metal nanoparticles are present in the water at a level of about 5-40 ppm, and wherein the composition manifests significant antimicrobial properties. Methods of use of the composition are described. The composition can be incorporated into a hydrogel with essentially no loss of antimicrobial properties. Various metal-containing compositions with unexpected biological efficacy are also disclosed.

Abstract: Methods and compositions are described for treating acne vulgaris and acne rosacea by administering compositions suitable for oral administration. Suitable compositions contain high dosages of the vitamin nicotinamide combined with much lower dosages of azelaic acid.

Abstract: The present invention relates to a pearl pigment obtained by coating the surface of a flaky powder with a colored metal or a colored metal oxide and further coating the surface of the above colored metal- or colored metal oxide-coated flaky powder with a colorless metal or a colorless metal oxide, wherein when the pearl pigment is applied onto the surface of black artificial leather in an average amount of 0.05 mg/cm2 and the intensity of light reflected from the pearl pigment is measured using illuminant C at a 2° viewing angle with a spectrophotometric colorimeter which is provided with a sheet polarizer S on the light incident side and a sheet polarizer P on the light receiving side, the powder reflection light which is incident to the pearl pigment as a measurement sample at an angle of 45° to the direction normal to the surface of the sample and is received in the direction normal to the surface of the sample has absolute values a* and b* of 10 or less, and make-up cosmetics containing the pearl pigment.

Abstract: A carrier system for transport of functional chemicals in substrates, such as fiber and plastic materials, comprises a carrier compound and at least one functional chemical, whereby the carrier compound consists of micelles, liposomes, lyotropic liquid crystals, or intercalation compounds. The functional chemical that is transported by the carrier compound migrates into the substrate and has an anisotropic distribution therein. Methods for modification, for activation and deactivation in a subsequent application on substrates are described.

Abstract: Provided is a composition for the preservation of wood and other cellulosic materials. The composition comprises a dispersion of micronized inorganic compounds and/or organic biocides in an organic carrier. Also provided is a method for making the composition.

Abstract: A material includes a surface and a reactive agent that is located at the surface of the material, covalently attached to a backbone of the material, and/or located within the material. The reactive agent has nitrite reductase activity, nitrate reductase activity, and/or nitrosothiol reductase activity. The reactive agent also converts at least one of nitrites, nitrates and nitrosothiols to nitric oxide when in contact with blood. A reproducible nitrosothiol sensor is also disclosed.

Abstract: Briefly described, embodiments of this disclosure, among others, include compositions, gels, methods for synthesizing multifunctional silica based nanoparticle gel, method of treating, preventing, or both treating and preventing, a disease in a plant species, method for simultaneously treating citrus plants for citrus canker and preventing the invasion of an Asian Citrus Psyllid (ACP) vector that carries the pathogen and spreads the citrus greening disease in citrus plants, and the like.

Abstract: The present invention provides a method for controlling toxicity of metallic particles and a low-toxicity composite of metallic nanoparticles and inorganic clay. The metallic nanoparticles are effective in preventing infection and in skinning over, and thus suitable for treating scalds/burns. In the composite, the weight ratio of metallic nanoparticles to inorganic clay preferably ranges 0.1/99.9 to 6.0/94.0 in a size of about 5 to 100 nm. Preferably, the metal is silver and the inorganic clay is nano silicate platelets.

Abstract: Compositions and methods for treating inflammation in mammalian tissue are provided using substantially continuously, in situ generated, anti-inflammatory effective amounts of hydrogen peroxide.

Abstract: The invention consists of a granulated fertilizer which contains iron (11 to 13%), zinc (3 to 9%), manganese (0.1 to 2.5%), copper (0.5 to 0.7%), in the form of sulphates, also ammonium molybdate (0 to 0.1%) and a Caolinite, Illite or Montmorillonite clay (45 to 57%), or a mixture of them in any proportion. All the percentages by weight are based on the total weight of the fertilizer. The product is 100% soluble, the high cationic exchange capacity which clays have allows the micronutrients to be adsorbed by the clay and prevent its leaching or reacting, making its assimilation by the plant more efficient and better. The use of sulphates in the soil, in the presence of water provoks an acidification of the soil which allows a better assimilation of the micronutrients in alkaline soils.

Abstract: The use of the polyamine known as spermidine, i.e., N-(3-aminopropyl)tetraminethylenediamine, as an active principle in the preparation of a composition for pharmaceutical or dietetic use in man for combating hair loss is disclosed.

Abstract: Multivitamin/Multimineral supplements are provided for supplementing iron and desirable nutrients in the diet of mammals. The supplements include an iron-amino acid chelate, a form of iron more bioavailable than traditional iron salts. The supplements may further include a pharmaceutically accepted salt form of iron as well as other nutritional vitamins and minerals. The supplements are useful for providing iron for pregnant and lactating females as well as for persons suffering from anemia.

Abstract: The present invention generally relates to a method of making nanoparticles and uses thereof. In particular, the invention relates to methods of making metal nanoparticles (MNPs). The invention also relates to antimicrobial uses of the nanoparticles.

Abstract: Provided herein are methods and materials for treating pulmonary hypertension (PH) in a subject. Also provided herein is a method of diagnosing whether a has PH by detecting a PH marker. A PKG pulmonary hypertension marker has been identified and may be useful in predicting PH disease progression and assessing a subject's response to PH therapy.

Abstract: The invention relates to a non-thermal plasma for treatment of a surface, particularly for the treatment of a wound (1), wherein the plasma comprises a partially ionized carrier gas and at least one additive, which preferably has a sterilizing effect on the treated surface and/or improves the healing of the wound (1). Further, the invention relates to a corresponding apparatus and method.

Abstract: A method for treating a wound, and a dressing for wound care management comprising a three-dimensional body of glass-based fibers comprising one or more glass-formers selected from the group consisting of P2O5, SiO2, and B2O3; at least about 25 wt % of the fibers have a diameter between about 200 nm and about 4000 nm, and a length:width aspect ratio of at least about 10. In another form, the glasses are in the form of particles in an ointment or cream applied to a wound. In yet other forms the glasses are employed as fibers formed into sutures for closing a wound, or as particles in a surgical glue for closing a wound.

Abstract: A wastewater treatment system for removing settled material from a supply of wastewater includes an open-top clarifier tank for holding wastewater having a minimum upper surface level, a support member supported above the clarifier tank and a wastewater treatment module positioned to be located at least partially below the clarifier tank upper surface level so as to have a submerged portion within the wastewater contained within the clarifier tank. At least part of the submerged portion, which can include an effluent supply conduit, has an outer surface formed of an anti-biologic material. The anti-biologic material inhibits the growth of algae within the wastewater and on the anti-biologic surface. The anti-biologic material can be a copper material, and can be provided on a base material such as stainless steel.

Abstract: A cleaning medium or formulation that contains a sporicidal composition is described. The composition includes about 0.1-20% weight/weight of a germinant agent, about 0.01-75% w/w of an antimicrobial agent, in terms of dry or wet total weight, and which is admixed with water to generate a solution with a pH of 3.5-9.5. The composition can help trigger the germination of spores, in particular C. difficile, and subsequently deactivate or kill the spores. A means of applying the cleaning formulation in a medium and process for cleaning are also described.

Abstract: A cosmetic composition with superior moisturizing benefits comprising from approximately 0.3% to approximately 0.9% by weight of bio-chelated mineral blend comprising silicon, magnesium, copper, iron, zinc, and calcium, and at least approximately 85.0% by weight of a humectant blend. Preferably, the bio-chelated mineral blend comprise Saccharomyces zinc ferment, Saccharomyces copper ferment, Saccharomyces magnesium ferment, Saccharomyces iron ferment, Saccharomyces silicon ferment, and Saccharomyces calcium ferment in equal amounts, more preferably from approximately 0.05% to approximately 0.15% by weight of each component. The humectant blend preferably comprises glycerin, beet root extract, and Aloe barbadensis leaf polysaccharides.

Abstract: The invention provides compositions and devices for altering biological field effects and methods for their use in therapeutic and agricultural applications. In particular, the invention provides compositions including one or more elemental metals coated with one or more non-conducting or semi-conducting materials and methods for their application to animals (including humans) and/or plants.

Abstract: An adaptable component having antiviral and virucidal properties is disclosed. The component generally comprises of a metal impregnated activated carbon cloth, an inner layer positioned along one side of the cloth and an outer layer positioned along the opposite side of the cloth. The layers can be attached together along all or a portion of a perimeter. The component can also have a protective membrane positioned between the outer layer and the activated carbon cloth. The components can be of benefit used in facemask composite, medical clothing such as gowns and scrubs, bed linen and protective clothing for military purposes.

Abstract: A method of treating neoplastic disease in a human or animal patient is provided comprising administering to the patient an anti-neoplastic effective amount of a composition comprising as the sole pharmaceutically active components (a) copper gluconate or copper orotate; (b) sodium salicylate; (c) vitamin C; (d) manganese gluconate or manganese orotate; and optionally one or more of (e) iron gluconate or iron orotate; (f) sublimed sulphur; and (g) zinc gluconate or zinc orotate.

Abstract: The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix.

Abstract: Goniochromatic/light reflecting cosmetic compositions well suited for making up the skin, lips, hair or integuments, contain (a) at least one goniochromatic coloring agent and (b) an amount of light reflective particles different from said at least one goniochromatic coloring agent and selected from the group consisting of (i) particles of a natural or synthetic substrate at least partially coated with at least one layer of at least one metal, (ii) particles of a synthetic substrate at least partially coated with at least one layer of at least one metallic compound, (iii) particles which comprise a stack of at least two layers of materials having different refractive indices, at least one of such layers optionally comprising a polymer, and (iv) metal oxide particles, formulated into (c) a topically applicable, physiologically acceptable medium therefor.

Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.

Abstract: Strategies that dramatically reduce leaching of water-soluble metal-containing biocides from treated biodegradable products. Aqueous, preservative compositions of the present invention incorporate one or more water-soluble metal species having biocidal activity and one or more agents that increase the leaching resistance of these metal species when impregnated into biodegradable products. Using one or more of these agents allows usage rates of the biocide impregnants to be dramatically lowered at the time of impregnation of the products. Because less of the metal biocide leaches in the presence of these agent(s), less biocide has to be added in order to meet desired loading goals. Generally, an agent of the present invention that reduces leaching of metal biocides is water soluble, is substantially nonionic in aqueous media, has a molecular weight greater than about 100, and has a vapor pressure less than that of water at standard temperature.

Abstract: Composition and methods for alleviating or eliminating age related skin conditions by providing an effective amount of one or more copper, zinc and copper-zinc compositions are disclosed. Treatment is accomplished through the use of topical compositions containing one or more copper or zinc salts and/or copper-zinc compounds or complexes, particularly copper-zinc malonate active ingredient.

Abstract: A trace element solution includes at least the metals: zinc, manganese, selenium, and copper, and comprises a concentration of the metal(s) of at least 90 mg/ml. The solution may comprise the following concentrations: at least 60 mg/ml zinc; at least 10 mg/ml manganese; at least 5 mg/ml selenium; and at least 15 mg/ml copper. The solution may furthermore comprise chromium and iodine.

Abstract: Metal carnitine chelates comprising carnitine chelated to a nutritionally relevant metal can be used for general nutrition as well as well as to treat a variety of health related problems and symptoms. For example, metal carnitine chelates can be used to maintain good cardiovascular health, increase male fertility, enhance weight loss, provide mineral and/or carnitine supplements for mineral- and/or carnitine-deficient subjects, and reduce alcohol dependency and associated symptoms. Nutritionally relevant metals that can be used include copper, zinc, magnesium, calcium, iron, chromium, and manganese, to name a few.

Abstract: The present invention provides a composition for topical treatment of skin and mucosal membrane lesions comprising a synergistic combination of copper compound and hypericum perforatum extract.

Abstract: In one embodiment, an antibacterial material includes at least one microparticles selected from tungsten oxide microparticles and tungsten oxide complex microparticles. The microparticles, which are undergone a test to evaluate viable cell count by inoculating in a test piece, to which the microparticles are adhered in a range of 0.02 mg/cm2 or more and 40 mg/cm2 or less, at least one bacterium selected from among Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, and enterohemorrhagic Escherichia coli, and storing for 24 hours, have an antibacterial activity value R of 0.1 or more expressed by the following: R=log(B1/C1) where, B1 denotes an average value (number) of viable cell count after storing an untreated test piece for 24 hours, and C1 denotes an average value (number) of viable cell count after storing the test piece on which the microparticles are coated for 24 hours.

Abstract: The present invention provides methods for treating or limiting development of age-related macular degeneration, as well as methods for identifying compound suitable for such use.

Abstract: A new, novel and useful disinfection and purification system comprised of organic compounds in synergistic action with selected metal ions and method of manufacture and use. One of the benefits that is derived from this system is the ability to quickly and easily treat a surface, fluid or medium for disinfection of bacteria, fungi, viruses, algae and protozoans, with a non-toxic, non-chlorinated mixture that effectively kills all such organisms in minutes or hours. The disinfection and purification system remains effective for long periods of time maintaining its disinfection capacity making it highly effective for stored or transported mediums such as potable drinking water. The disinfection and purification system may be incorporated with carbon block or membrane filters to disinfect filtered liquids such as water to render it potable.

Abstract: The invention relates to a medical implant made of a metallic material. After fulfilling its temporary support function, the implant is degraded by corrosion at a predetermined rate. Negative long-term effects are thus avoided.

Abstract: A long-lasting anti-microbial composition is provided, which includes one or more polymer or oligomer and a plurality of nanowires distributed therein, wherein the nanowires have an aspect ratio of more than 20 and the nanowires form a network-like structure. An anti-microbial film and spray including the composition are also provided.

Abstract: The present invention provides a coating comprising a bioactive material and an antimicrobial agent, wherein the concentration of said antimicrobial agent varies throughout the thickness of the coating.

Abstract: The present invention discloses a coating for a medical implant, wherein at least a part of said coating contains an osseointegration agent and the same and/or a different part of the coating contains an antimicrobial metal agent.

Abstract: The present invention provides a novel method for treating oral conditions and upper gastrointestinal conditions in a subject by providing an inventive oral dosage form of a pharmaceutical composition comprising an effective amount of at least one antifungal and optionally a flavor modifier and/or salivation component such as an herbal component. In the present invention, the subjects have either not been diagnosed or do not have active or recurrent fungal infections. Specifically, the present invention is directed to chewable dosage forms.

Abstract: Composition and methods for alleviating or eliminating wounds and/burns by providing an effective amount of one or more copper, zinc and copper-zinc compositions are disclosed. Treatment is accomplished through the use of topical compositions containing one or more copper or zinc salts and/or copper-zinc compounds or complexes, particularly copper-zinc malonate active ingredient.

Abstract: A facial mask for use in decreasing the transmission of one or more than one human pathogen to and from a human wearer of the facial mask, the facial mask comprising a facepiece; where the facepiece comprises three or more than three layers; where one or more than one of the three or more than three layers comprises a fabric comprising one or more than one binding substance comprising one or more than one human pathogen binding group for chemically attaching the human pathogen to the binding substance; where the fabric further comprises one or more than one type of multivalent metallic ion or metallic salt; and where one or more than one of the three or more than three layers comprises a heat-moldable fabric.

Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.

Abstract: The present invention concerns methods and compositions related to a chelator and a HHRT ligand. In specific embodiments of the invention the chelator is conjugated to the HHRT ligand. In another specific embodiment of the invention, the chelator is chelated to a metal. In a particular embodiment of the invention, there is a metal species that is chelated to a chelator, which is then directly or indirectly conjugated to a HHRT ligand. In some embodiments, the composition further comprises a therapeutic agent. In particular cases, the compositions are employed for cancer diagnosis and/or therapy.

Abstract: A marine anti-bio-fouling coating 10, for application onto the surface of a marine article 12. The coating 10 comprises a self-levelling, self-curing epoxy resin primer adhesive 14, an adhesive modified epoxy resin binder adhesive 16 and granulated Copper Nickel alloy 18. When a coated marine article 12 is immersed in water a chemical reaction occurs between the water and the Copper Nickel alloy 18 which causes a film of a complex metal oxide 20 to form on the exterior surface of the layer of Copper Nickel alloy granules 18. The oxide film 20 forms an inhospitable environment to aquatic organisms and aquatic borers, thereby preventing bio-fouling occurring on the coated marine article. A method of applying the coating 10 to a marine article 12 is also provided.

Abstract: A gel that includes a fungicide or an anti-bacterial is contained within a single dosage packet that includes a tapered nozzle end and a body. The fungicide or anti-bacterial gel is applied to the hoof of a horse by opening the packet at the tapered nozzle end and squeezing the body. The gel is then spread over the frog and sole of the hoof with a portion of the packet. The gel is heated so that it spreads to recessed areas of the hoof that can contain the bacterial and fungus infections.