Abstract: A composition for use in treating or preventing a respiratory virus which comprises: (a) at least one water soluble zinc, copper, selenium and/or manganese compound able in aqueous solution to dissociate into zinc, copper selenium and/or manganese ions; (b) at least one water soluble ammonium agent able in aqueous solution to dissociate into ammonium ions (c) at least one acid, and (d) water.
Abstract: The present invention relates to micro-sized particles having anti-biocontaminant properties. Each particle is comprised of a central metal core, or support structure, (for example, alumina oxide) and has on its surface, one or more anti-biocontaminant metals and at least one redox agent.
Abstract: A wood preservative includes injectable particles comprising one or more sparingly soluble copper salts. The copper-based particles are sufficiently insoluble so as to not be easily removed by leaching but are sufficiently soluble to exhibit toxicity to primary organisms primarily responsible for the decay of the wood. Exemplary particles contain for example copper hydroxide, basic copper carbonate, copper carbonate, basic copper sulfates including particularly tribasic copper sulfate, basic copper nitrates, copper oxychlorides, copper borates, basic copper borates, and mixtures thereof. The particles typically have a size distribution in which at least 50% of particles have a diameter smaller than 0.25 ?m, 0.2 ?m, or 0.15 ?m. At least about 20% and even more than 75% of the weight of the particles may be composed of the substantially crystalline copper salt. Wood or a wood product may be impregnated with copper based particles of the invention.
Abstract: An antimicrobial formulation containing a quinone, such as a benzoquinone or hydroquinone, and a copper salt. The formulation may in particular be used against staphylococci or propionibacteria, more particularly to treat skin and skin structure conditions such as acne.
Type:
Application
Filed:
February 20, 2007
Publication date:
October 1, 2009
Applicant:
SYNTOPIX LIMITED
Inventors:
Scott Seville, Priscila Gottardello, Daniel James Fitzgerald
Abstract: An antibacterial formulation which comprises: (a) at least one water soluble copper compound able to form copper ions upon dissolution in an aqueous medium; (b) at least one water soluble ammonium agent able to form ammonium ions upon dissolution in an aqueous medium; (c) at least one water soluble acid, and (d) an aqueous medium within which components (a), (b) and (c) are dissolved, said formulation having (e) an acidic pH and (f) an electrolytic potential in excess of 50 millivolts.
Abstract: This invention relates to high surface area materials, such as nanoparticles, that are coated with metal ions. These modified nanoparticles have active sites that bind various gases and/or odorous compounds, thereby removing these compounds from a medium such as air or water. Metal ions are adsorbed onto the surface of the nanoparticle and bound strongly to the surface. By selection of the metal ion, specific gaseous compounds and/or odorous compounds can be targeted and removed efficiently and effectively from both aqueous phase and from the air. The modified nanoparticles are useful in numerous article of manufacture for industrial and consumer use.
Abstract: The present invention comprises methods and compositions for making a silver-containing antimicrobial hydrophilic material. More particularly, the present invention comprises methods and compositions for stabilized silver antimicrobial devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide, and an active agent. The matrix may be formed into any desired shape for its desired uses.
Abstract: A metal nanodot material is formed by ion-exchange with an ETS zeolite, followed by activation to form metallic nanodots. The nanodot may be formed from silver, nickel, copper, gold or a platinum group metal.
Type:
Application
Filed:
November 17, 2008
Publication date:
August 13, 2009
Applicant:
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
Abstract: An embodiment of the invention is a treatment for the mitigation and prevention of systemic infection of plants by Xylella fastidiosa using materials derived from bactericidal metals wherein one metal is silver. The candidate bactericidal metal is preferably introduced in metallic, nanocrystalline, salt form, chelated form, or otherwise coupled form. Metal atoms, ions, molecules, or clusters are introduced to the plant to the plant by injection, ballistic insertion, pneumatic insertion, mechanical insertion, manual insertion, root application, aerosolization, or spray in sufficient concentration to treat, cure, and/or prevent plant disease or reduced productivity caused by X. fastidiosa.
Abstract: Use, method of manufacturing a pharmaceutical composition, pharmaceutical composition for the treatment of skin ailments comprising a therapeutic quantity in aqueous solution of nitric acid of 5 to 15 mmol/ml of pharmaceutical composition, and also comprising a zinc salt at a concentration of 0.01 to 0.015 mg of Zn2+ ions/ml as well as a copper salt at a concentration of 0.01 to 0.015 mg of Cu2+ ions/ml of pharmaceutical composition and its medical device.
Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.
Type:
Application
Filed:
April 3, 2009
Publication date:
July 23, 2009
Applicant:
Z-MEDICA, CORPORATION
Inventors:
Raymond Huey, Denny Lo, Daniel J. Burns
Abstract: The present invention relates to compositions that may be swallowable, chewable or dissolvable, comprising various vitamins and minerals, and in a specific embodiment comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and methods for using these compositions for nutritional supplementation in subjects undergoing physiologically stressful events, such as, for example and without limitation, pregnancy, lactation or any disease state.
Abstract: This invention relates to a non-medicinal food additive that is an animal growth promoter containing 99% pure zeolite partially or totally exchanged with a Cm+ cation, i.e., a synthetic zeolite, having the general formula I below: 1 m ? yC m + ? ( 1 - y ) ? 1 n ? M n + ? AlO 2 ? xSiO 2 in which x is greater than 1 and advantageously between 1 and 15; Mn+ represents an alkaline or alkaline earth exchangeable ion, advantageously Na+, K+, Ca2+ or Li+; n is between 1 and 2; y is the exchange rate and is between 0.001 and 1; Cm+ is a metallic cation chosen from among copper Cu2+, silver Ag+ or zinc Zn2+; m is between 1 and 2; this invention also relates to an additive premix and a supplemented food containing same and a method of improving the growth of animals.
Type:
Application
Filed:
April 11, 2006
Publication date:
June 18, 2009
Applicants:
INSTITUT REGIONAL DES MATERIAUX AVANCES (IRMA), EVIALIS
Abstract: The present invention includes compositions and methods for the treatment of inflammatory disease (e.g. asthma, COPD, inflammatory bowel disease, atopic dermatitis, atopy, allergy, allergic rhinitis, scleroderma, and the like), relating to inhibiting a chitinase-like molecule. The invention further includes methods to identify new compounds for the treatment of inflammatory disease, including, but not limited to, asthma, COPD and the like. This is because the present invention demonstrates, for the first time, that expression of IL-13, and of a chitinase-like molecule, mediates and/or is associated with inflammatory disease and that inhibiting the chitinase-like molecule treats and even prevents, the disease. Thus, the invention relates to the novel discovery that inhibiting a chitinase-like molecule treats and prevents an inflammatory disease.
Abstract: The invention relates to biologically active nanoparticles of a carbonate-substituted non-stoichiometric hydroxyapatite, having: a) a crystallinity degree CD lower than 40%, the crystallinity degree being defined as CD=(1?X/Y)·100 wherein: Y=height of the diffraction maximum at 2?=33°, X=height of the diffraction background at 2?=33° of the nanoparticles X-ray diffraction pattern; b) a length L ranging from 20 to 200 nm and a width W ranging from 5 to 30 nm; and c) an aspect ratio AR comprised between 2 and 40, the aspect ratio being defined as AR=L/W. The biologically active nanoparticles of the invention find a preferred use in oral or dental hygiene applications and may be formulated as compositions for oral or dental hygiene such as, for example, solutions, suspensions, oils, gels or other solid products.
Type:
Application
Filed:
May 30, 2006
Publication date:
May 21, 2009
Inventors:
Giancarlo Gazzaniga, Norberto Roveri, Lia Rimondini, Barbara Palazzo, Michele Iafisco, Paolo Gualandi
Abstract: A wood preservative includes injectable particles comprising one or more sparingly soluble copper salts. The copper-based particles are sufficiently insoluble so as to not be easily removed by leaching but are sufficiently soluble to exhibit toxicity to primary organisms primarily responsible for the decay of the wood. Exemplary particles contain for example copper hydroxide, basic copper carbonate, copper carbonate, basic copper sulfates including particularly tribasic copper sulfate, basic copper nitrates, copper oxychlorides, copper borates, basic copper borates, and mixtures thereof. The particles typically have a size distribution in which at least 50% of particles have a diameter smaller than 0.25 ?m, 0.2 ?m, or 0.15 ?m. At least about 20% and even more than 75% of the weight of the particles may be composed of the substantially crystalline copper salt. Wood or a wood product may be impregnated with copper-based particles of the invention.
Abstract: The present invention provides compositions and methods for decreasing photosensitivity induced by photodynamic therapy (PDT). The compositions and methods of the present method employ porphyrin complexing molecules as agents for reducing photosensitivity.
Abstract: A material for the treatment or prophylaxis of microbial, including bacterial, infections, comprising a metal species and a polymer, wherein the polymer stabilises the metal species. Compositions and devices comprising the material. A method for the treatment or prophylaxis of microbial, including bacterial, infections, comprising the use of such a material, composition or device.
Abstract: There is provided a method for treating a fluid with an anti-microbial agent comprising the steps of: (a) contacting the fluid with a solid material containing an anti-microbial agent; and, (b) abrading an interface of the solid material and removing particles therefrom and exposing an underlying surface of the solid material to the fluid, thereby facilitating release of the antimicrobial agent of the underlying surface of the solid material and/or the removed particles into the fluid. The solid material comprises an anti-microbial agent dispersed and/or embedded in a solid carrier. Typically, the anti-microbial agent is one or more of a metal, metal oxide, metal compound, metal salt, metal-ligand complex or derivatives thereof based on silver, copper and zinc.
Type:
Application
Filed:
September 7, 2005
Publication date:
April 23, 2009
Applicant:
BACSTOP CORPORATION PTY LTD
Inventors:
Allen Roland Parsons, Donald William Atkinson
Abstract: A topical product to protect the skin from free radicals is disclosed in one embodiment of the invention as including a carrier medium for topical application to the skin. A sacrificial material that is compatible with the skin is interspersed with the carrier medium. This sacrificial material may be selected to react with free radicals within the skin. The sacrificial material may be further selected to react with water to produce hydrogen (a powerful antioxidant) and a reaction product that is also compatible with the skin. In this way, both the sacrificial material and the hydrogen will react with free radicals to provide protection against free radicals.
Abstract: Complexes of copper and/or zinc with molybdate and/or tungstate were solubilized in ammonia or ammoniacal solution providing preservative solutions that fully penetrate wood. With loss of the ammonia from the wood, the complexes were stably retained in the wood providing a long lasting preservative.
Type:
Grant
Filed:
December 21, 2006
Date of Patent:
March 3, 2009
Assignee:
E. I. dupont de Nemours and Company
Inventors:
Albert Gordon Anderson, John Feaster, Damini Patel, Mark Scialdone
Abstract: Preservative composition for lignocellulosic-based composites providing rapid and long-lasting protection against insect and fungal attack, in both low and high moisture environments, through the use of a combination of higher solubility and lower solubility borates. Pesticidal amounts of a lower solubility borate and a higher solubility borate are combined before or during their incorporation into a lignocellulosic-based composite. Useful low solubility borates include copper borate, zinc borate and barium metaborate. Useful high solubility borates include boric acid, boric oxide, ammonium borate and alkali metal borates such as sodium borate. Some alkaline earth metal borates, including calcium borates, calcium magnesium borates, magnesium borates and calcium sodium borates, are of intermediate solubility and may be used effectively as either a low soluble or high soluble borate depending on the combination used.
Type:
Application
Filed:
October 22, 2008
Publication date:
February 26, 2009
Applicant:
U.S. Borax Inc.
Inventors:
Jeffrey D. Lloyd, Mark J. Manning, Frederick M. Ascherl
Abstract: The present invention is drawn to disinfectant or sterilant compositions, which are human safe, e.g., food grade or food safe. In one embodiment, an aqueous disinfectant or sterilant composition can comprise an aqueous vehicle, including water, from 0.001 wt % to 50 wt % of a peracid, and from 0.001 wt % to 25 wt % of a peroxide. Additionally, from 0.001 ppm to 50,000 ppm by weight of a transition metal based on the aqueous vehicle content can also be present. The composition can be substantially free of aldehydes. Alternatively or additionally, the transition metal can be in the form of a colloidal transition metal.
Abstract: A method of disinfecting surfaces said method comprising applying a disinfectant solution to surface to be disinfected and allowing the solvent to evaporate or wiping the excess solution from the surface after a period of time wherein the solution is an antimicrobial metal ion-acid solution.
Abstract: A herbal topical composition is used having complexed trace minerals capable of effectively reducing bone and joint inflammation by inhibiting inflammation pathways and in particular COX-2. The herbal composition having trace elements in a topical carrier reduces inflammation while avoiding the side effects associated with traditional drug therapy.
Abstract: The present invention relates to methods and compositions effective in preventing, attenuating, inhibiting the progression of, and treating eye diseases, e.g., age-related macular degeneration (AMD). The compositions comprise, as an active ingredient, an effective amount of 3,3?-diindolylmethane (DIM) and/or its precursor indole-3-carbinol (I3C). The compositions can further comprise additional agents such as carotenoids and other phytochemicals, which produce a synergistic effect in preventing, attenuating, inhibiting the progression of, and treating AMD and other eye diseases such as glaucoma, cataracts and diabetic retinopathy (DR). The compositions are particularly effective in treating and preventing wet AMD, and in preventing or inhibiting the progression of dry AMD (non-neovascular) to wet AMD (neovascular).
Abstract: A new, novel and useful disinfection and purification system comprised of organic compounds in synergistic action with selected metal ions and method of manufacture and use. One of the benefits that is derived from this system is the ability to quickly and easily treat a surface, fluid or medium for disinfection of bacteria, fungi, viruses, algae and protozoans, with a non-toxic, non-chlorinated mixture that effectively kills all such organisms in minutes or hours. The disinfection and purification system remains effective for long periods of time maintaining its disinfection capacity making it highly effective for stored or transported mediums such as potable drinking water. The disinfection and purification system may be incorporated with carbon block or membrane filters to disinfect filtered liquids such as water to render it potable.
Abstract: The present invention provides wood preservative compositions comprising micronized particles. In one embodiment, the composition comprises dispersions of micronized metal or metal compounds. In another embodiment, the wood preservative composition comprises an inorganic component comprising a metal or metal compound and organic biocide. When the composition comprises an inorganic component and an organic biocide, the inorganic component or the organic biocide or both are present as micronized particles. When compositions of the present invention are used for preservation of wood, there is minimal leaching of the metal and biocide from the wood.
Abstract: The invention concerns a composition containing red yeast rice and other components, as a chemopreventative agent to reduce the risk of cancer.
Abstract: The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
Type:
Grant
Filed:
June 9, 2003
Date of Patent:
December 30, 2008
Assignee:
Aeolus Pharmaceuticals, Inc.
Inventors:
James D. Crapo, Irwin Fridovich, Tim Oury, Brian J. Day, Rodney J. Folz, Bruce A. Freeman, Michael P. Trova, Ines Batinic-Haberle
Abstract: The invention provides a method for treating and healing sores, cold sores, cutaneous openings, ulcerations, lesions, abrasions, burns and skin conditions comprising applying to a body surface exhibiting the same, a material incorporating water-in-soluble copper compounds which release cu+ ions, cu++ ions or combinations thereof upon contact with a fluid to effect the treatment and healing thereof.
Abstract: A method of treating chloraminated water by adding copper ions is disclosed. The addition of copper ions inhibits microbial action in the water, thus reducing nitrification of ammonia and maintaining chloramine levels.
Abstract: The invention relates to an antibacterial sol-gel coating solution, a process for preparing the antibacterial sol-gel coating solution, an antibacterial article, and a process and an apparatus for producing the antibacterial article. Said antibacterial sol-gel coating solution comprises a. at least one substance selected from the group consisting of Ti or Si-containing compounds capable of hydrolyzing to form a base film; b. a regulating agent capable of regulating the hydrolysis rate of the Ti or Si-containing compounds; c. an organic solvent; d. water; and e. at least one soluble compound of antibacterial metal selected from the group consisting of Ag, Cu, Mg, Zn, Sn, Fe, Co, Ni, and Ce; wherein a, b and a portion of c are first mixed to form a solution I, d and the rest of c are then mixed and added into solution I to form a dispersion II, and then e is added into dispersion II to form the antibacterial sol-gel coating solution.
Type:
Application
Filed:
December 12, 2005
Publication date:
December 11, 2008
Applicant:
QINHUANGDAO YIPENG SPECIAL GLASS CO, LTD
Abstract: An anti-fomitic device in the form of a bag or envelope forms a cover for an object for preventing cross-infection by bacteria and other pathogens that may reside on the object. The anti-fomitic device is a flat, flexible bag or envelope with a closure mechanism at one or both ends of the bag or envelope, having a sterile interior that is sealed during manufacture to maintain sterility. Therefore, no outer wrapping for the anti-fomitic device is required. The anti-fomitic device is inverted when used to cover the object and results in an ultimate outer surface that is initially sterile. Materials for the coverings/bags serve as a barrier to the transmission of pathogens.
Type:
Application
Filed:
May 30, 2008
Publication date:
December 4, 2008
Inventors:
Marvin E. HASKIN, Jon L. Roberts, Christopher B. Kilner
Abstract: A simple and cost effective method of producing a polymer composite comprising a polymer matrix having metal nanoparticles incorporated therein comprises the steps of (i) mixing metal nanoparticles with a polymer dope; and (ii) solidifying the polymer composite from the dope. Antimicrobial fibres are produced by extruding a dope solution (1) held in a container (2) provided with an inert atmosphere (3) into a coagulating bath (4) containing a coagulant (5), by means of a pump (6) and a spinneret head (7) completely immersed in the coagulant. The dope is filtered via a filter (8) positioned behind the spinneret.
Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
Abstract: The present invention relates to the use of a combination of group B vitamins, trace element(s), at least one oil comprising essential ?-3 and/or ?-6 fatty acids and an excipient suitable for oral administration, for use in the simultaneous treatment of excess weight and slackening of the skin localized in the same area. The invention also relates to a corresponding food supplement.
Type:
Application
Filed:
December 15, 2006
Publication date:
November 27, 2008
Inventors:
Philippe Msika, Nathalie Piccardi, Pascale Cochet, Michel Moreau
Abstract: An anti-cancer composition having biocompatible materials, which can selectively exploit chemical variations between normal cells and cancer cells to inhibit or prevent the proliferation of cancerous cells and methods of use.
Abstract: The present invention relates to a nanostructural substance constituted from primary particles having a particle diameter of not more than 30 nm. In the nanostructural substance of the present invention, the primary particles have a small particle diameter, and a contact surface between the primary particles is small. In particular, since the nanostructural substance of the present invention has a large content of molecules existing at the surface thereof and, therefore, a high surface energy as compared to simple agglomerated particles, it is expected to more remarkably exhibit functions of the compound constituting the primary particles. In addition, titanium oxide particles constituted from the nanostructural substance comprising primary particles having a small particle diameter and a small contact area therebetween according to the present invention exhibit a high catalytic activity and can be suitably used, in particular, as a photocatalyst.
Abstract: An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.
Abstract: The present invention provides wood preservative compositions comprising micronized particles. In one embodiment, the composition comprises dispersions of micronized metal or metal compounds. In another embodiment, the wood preservative composition comprises an inorganic component comprising a metal or metal compound and organic biocide. When the composition comprises an inorganic component and an organic biocide, the inorganic component or the organic biocide or both are present as micronized particles. When compositions of the present invention are used for preservation of wood, there is minimal leaching of the metal and biocide from the wood.
Abstract: Described herein are combination methods, compositions and therapies for treating ophthalmic conditions or diseases arising from, associated with or leading to the overproduction of waste products in the visual cycle. Agents included within these combinations are 13-cis-retinyl derivatives; other agents included within these combinations are selected from vitamins, antioxidants, minerals, inducers of nitric oxide production, anti-inflammatory agents, and negatively-charged phospholipids. Such combination methods may be used as single or multiple administration therapies, or in combination with other agents or therapies.
Abstract: The present invention relates to an anti-bacterial, anti-virus, and anti-fungus composition, its preparation and use. The composition of the present invention mainly includes the following three ingredients in an adequate ratio: (A) a metal compound having a catalytic function; (B) ionic compound, and (C) an additive. The anti-bacterial, anti-virus, and anti-fungus composition of the present invention is capable of destroying viruses as well as killing bacterial and fungi. Therefore, the composition can be formulated as an aerosol and a film for applying to protection devices such as respirators, masks, gloves, filters, condoms, etc. The present composition can also be used in household, vehicle, hospital, school, restaurant, hotel, internet coffee shop for applying to filter of air-conditioner, tap, stool, interior of elevator and its keyboard.
Abstract: Systems and methods are provided herein that provide for promoting cellular health and treatment of cancer, and allied diseases such as diabetes and glaucoma.
Abstract: An aqueous wood preservation composition containing inorganic polymers of one or more of the following metals is disclosed; aluminum (approximately 3.8%-7.0% as Al2O3), zirconium (approximately 5.25%-9.1% as ZrO2), copper (approximately 0.7%-8.8% as CuO) and a fixing agent such as acetic acid or sodium acetate. The pH is adjusted to be between 2.0-4.0 using an inorganic base such as copper carbonate. The invention includes wood and cellulose fibers treated by the composition of the present invention as well as methods of preserving wood and cellulose fibers using the compositions.
Type:
Grant
Filed:
August 22, 2007
Date of Patent:
December 2, 2008
Assignee:
Sommerville Acquisitions Company, Inc.
Inventors:
Thomas L. Harper, Boris Reznikov, Allan Rosenberg