Orally Assimilable Or Injectable Composition Patents (Class 424/643)
  • Patent number: 5071658
    Abstract: A method of treating the prostate by intraprostatic injection of zinc ions in a concentration effective to increase the amount of prostatic antibacterial factor and to inhibit the rate of prostatic growth. The treatment is applied to patients with prostatitis, to patients with benign adenomatous hyperplasia of the prostate after prostatic resection and to patients with early prostatic carcinoma as an alternative to surgery as needed to provide long-term remission. The treatment is also applied prophylactically to prevent the development of prostatitis, particularly in males of advanced age.
    Type: Grant
    Filed: July 23, 1990
    Date of Patent: December 10, 1991
    Inventor: Mostafa S. Fahim
  • Patent number: 5069912
    Abstract: A method of treating skin disorders, inflamatory conditions and certain internal infections and disorders by administering, either externally by topical application or internally through oral ingestion, an effective amount of a mixture of mineral compounds in appropriate parts by weight of aluminum oxide hydrate, iron, magnesium oxide, silicon dioxide, sodium hydroxide and potassium hydroxide, along with trace amounts of copper, zinc, and calcium, with the balance of the mixture comprising ammonium sulfate or, in the case of topically applied formulations, a pharmaceutically acceptable carrier or diluent.
    Type: Grant
    Filed: August 31, 1990
    Date of Patent: December 3, 1991
    Inventor: Charles A. Jensen
  • Patent number: 5059416
    Abstract: A new delivery system for zinc compounds and the process for its preparation is disclosed, which has use in a variety of products including comestibles such as chewing gum compositions, confections, pharmaceuticals, food products such as vitamin preparations, dentifrice compositions and throat lozenges. More particularly, this invention relates to a process for preparing a zinc compound delivery system comprised of a zinc core material coated with a first hydrophilic coating comprising a hydrocolloid material and a second hydrophobic coating selected from the group consisting of fats, waxes and mixtures thereof. The delivery system provides enhanced masking of the bitter flavor characteristic of zinc compounds, as well as reduced grittiness with retained stability at the elevated temperatures of product formulation.
    Type: Grant
    Filed: June 26, 1989
    Date of Patent: October 22, 1991
    Assignee: Warner-Lambert Company
    Inventors: Subraman R. Cherukuri, Tommy L. Chau
  • Patent number: 5002970
    Abstract: An oral composition containing ionizable compounds of zinc flavor-masked with anethole and prepared in the forms of pleasant tasting lozenges, soft candies, syrups, powders and chewing gums for delivery of zinc to the oral and oral pharyngeal mucosa of a human with said composition being absent the taste or aftertaste of zinc, and being primarily intended for use in treating the common cold.
    Type: Grant
    Filed: April 18, 1988
    Date of Patent: March 26, 1991
    Inventor: George A. Eby, III
  • Patent number: 5000944
    Abstract: A zinc-containing antitartar oral product substantially free of astringency, containing as the essential agent, a zinc/polyphosphate complex having at least about a 50% water solubility, formed by the reaction or interaction of a zinc compound with a potassium or sodium polyphosphate by dissolving a zinc salt in a polyphosphate solution such as pyrophosphate, tripolyphosphate, hexametaphosphate and combinations thereof.
    Type: Grant
    Filed: June 9, 1989
    Date of Patent: March 19, 1991
    Assignee: Colgate-Palmolive Company
    Inventors: Michael Prencipe, Shamsul K. Bakar
  • Patent number: 4992259
    Abstract: A stable and clear aqueous solution of zinc salt useful as a mouthrinse and a gel dentifrice. In a preferred embodiment the aqueous solution comprises zinc chloride codissolved with a complexing agent of sodium gluconate, in a naturally derived anionic polymer of sodium carboxymethylcellulose. This solution is advantageous because it maintains clarity and chemical stability in temperatures of from about 4.degree. to about 50.degree. C. and may be alcohol-free. The anionic polymer acts as a buffer to provide a solution with a pH in a desirable range of from about 5.7 to about 6.5, which limits astringency and tartness.
    Type: Grant
    Filed: January 3, 1990
    Date of Patent: February 12, 1991
    Assignee: Johnson & Johnson Consumer Products, Inc.
    Inventors: Michael T. Schiraldi, Robert K. Denton, Jr.
  • Patent number: 4956385
    Abstract: This invention discloses and claims improved methods to reduce duration of common colds in humans through use of pharmaceutically acceptable zinc compounds topically and frequently applied to the oral mucosa by various means. The invention improves upon the prior art using zinc gluconate throat lozenges to reduce the duration of common colds and zinc borate intranasally as an astringent and decongestant in treatment of common colds.
    Type: Grant
    Filed: September 24, 1987
    Date of Patent: September 11, 1990
    Inventor: George A. Eby, III
  • Patent number: 4946688
    Abstract: A method of treating the prostate by intraprostatic injection of zinc ions in a concentration effective to increase the amount of prostatic antibacterial factor and to inhibit the rate of prostatic growth. The treatment is applied to patients with prostatitis, to patients with benign adenomatous hyperplasia of the prostate after prostatic resection and to patients which early prostatic carcinoma as an alternative to surgery as needed to provide long-term remission. The treatment is also applied prophylactically to prevent the development of prostatitis, particularly in males of advanced age.
    Type: Grant
    Filed: July 5, 1988
    Date of Patent: August 7, 1990
    Inventor: Mostafa S. Fahim
  • Patent number: 4937066
    Abstract: An ammonium or alkali metal zinc tartrate used in oral compositions such as mouthwashes, gingival and subgingival irrigating solutions, dentifrices, and the like as well as in other preparations for treating oral lesions.
    Type: Grant
    Filed: June 22, 1989
    Date of Patent: June 26, 1990
    Assignees: David G. Vlock, Lawrence Rosen
    Inventor: Richard S. Vlock
  • Patent number: 4931290
    Abstract: A method is disclosed for reducing the propensity of a dairy cow to develop severe milk fever upon calving comprising administering thereto a composition comprising a water-soluble calcium compound and a complexing agent for serum phosphorus.
    Type: Grant
    Filed: September 23, 1988
    Date of Patent: June 5, 1990
    Assignee: Domain, Inc.
    Inventor: Herbert J. Rebhan
  • Patent number: 4917881
    Abstract: There is disclosed a unique composition which essentially comprises a granule or cell or garlic having adhered thereto a suitable amount of zinc oxide. The zinc oxide acts as a buffer to alleviate the unpleasant aftereffects which are cused by the ingestion or consumption of garlic. In this manner zinc oxide functions to digestively avoid such unpleasant aftereffects associated with the ingestion or consumption of garlic.
    Type: Grant
    Filed: March 4, 1988
    Date of Patent: April 17, 1990
    Inventor: Daniel S. Gray
  • Patent number: 4847067
    Abstract: A mold and dust inhibiting composition which has particular utility in connection with the storage and handling of animal feeds, grains, and hay, and also in connection with the use of animal litter such as poultry litter, as well as having general utility for controlling both mold and dust. The composition of the invention is an aqueous solution of one or more salts of propionic acid, one or more deliquescent substances, and also preferably one or more humectants. Propionate ions are made available for mold control by this solution just as effectively as propionic acid, but without the disadvantages of propionic acid including a bad odor, serious corrosive characteristics, and high volatility and hence short residual time. The deliquescent, and preferably also the humectant, prevent moisture from migrating toward container walls where there is a large day/night temperature differential, and also prevent dry regions from developing and producing potentially harmful dust.
    Type: Grant
    Filed: February 26, 1988
    Date of Patent: July 11, 1989
    Inventor: Richard D. Thomas
  • Patent number: RE33465
    Abstract: The invention disclosed and claimed is a method to reduce duration of common colds in humans as evinced by reduction of duration of 10 common cold symptoms through use of zinc gluconate topically and frequently applied to the oral mucosa. The invention improves upon the prior art using zinc intranasally as an astringent and decongestant in treatment of common colds. Results of a clinical study are presented in support of disclosure and claims.
    Type: Grant
    Filed: April 4, 1986
    Date of Patent: November 27, 1990
    Inventor: George A. Eby, III