Ferrous Patents (Class 424/648)
  • Patent number: 10188677
    Abstract: In one of its aspects, the present invention provides a composition comprising: (i) a non-encapsulated iron salt, and (ii) a carrier comprising digestible edible oil that is a liquid at 20° C. This composition advantageously provides iron in a form that is easily administered to an infant or adult. When taken directly by mouth or added to food or infant formula, the composition has a desirably bland flavor and is easy to consume. Moreover, the high density of iron per unit volume of the composition results in a minimal volume of liquid to be administered. This makes the composition relatively innocuous and easy for infants to consume. Related aspects of the present invention are also described—e.g., uses, articles of manufacture and the like.
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: January 29, 2019
    Assignee: THE D DROPS COMPANY INC.
    Inventor: Reinhold Vieth
  • Patent number: 10034489
    Abstract: A liquid food composition that can be conveniently ingested or given with a tube and contains reduced aggregates in the composition is provided. A liquid food composition that shows fluidity in the neutral region, but solidifies in the stomach environment is further provided. According to the production method of the present invention, generation of fine particles in the production process of a liquid food composition containing a divalent metal salt, a protein, and water-soluble dietary fibers is reduced. Therefore, emulsification stability of the composition is improved, clogging of aggregates in strainer disposed in the production line etc. are eliminated, and thus the composition can be efficiently produced.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: July 31, 2018
    Assignee: Kaneka Corporation
    Inventors: Hiroaki Inoue, Masao Sato, Tadashi Moroshima, Ken Uekita, Shinichi Yokota, Yui Kawashima, Tadaaki Hashimoto, Kazuya Hamada
  • Patent number: 9757547
    Abstract: A blood coagulating device can include an absorbent body; and a hemostatic lysine composition associated with the body. The body can have a cylindrical or conical member having a first end having the hemostatic composition, the first end being configured for insertion into a nasal passageway. A method for coagulating blood can include providing a powdered hemostatic lysine composition; and applying the powdered hemostatic lysine composition to blood so as to cause the blood to coagulate and form a clot. The coagulation can occur in a nasal passageway away from a blood vessel. The method can include providing at least one absorbent member having the powdered hemostatic lysine composition; and applying the at least one absorbent member to the blood so that the powdered hemostatic lysine composition causes the blood to coagulate and clot.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: September 12, 2017
    Assignee: Park City Bio, LLC
    Inventors: Jonathan M. Benns, Matthew C. Lawyer
  • Patent number: 9492481
    Abstract: A bioactive agent in which the bioactive effectiveness of ferrous iron salt and/or ferric ferrous iron salt contained therein is stabilized, making long term preservation possible, so that the bioactive agent can be useful as an original solution for medical use, as a soil conditioner, or the like. An iron-magnesium mixture solution is provided in the invention, wherein the iron-magnesium mixture solution is produced by mixing an aqueous solution containing a ferrous iron salt and/or a ferric ferrous iron salt in a concentration of not less than 0.5 mol/L as iron in the ferrous iron salt and/or the ferric ferrous iron salt, and an aqueous solution containing a magnesium salt in a concentration of not less than 0.2 mol/L as magnesium in the magnesium salt.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: November 15, 2016
    Assignee: I.B.E. Co., Ltd.
    Inventors: Shinji Makino, Mie Makino
  • Patent number: 9000036
    Abstract: Methods for treating neoplasm, tumors and cancers, using one or more tumor treating drug carriers, haptens and anticancer drugs, alone or in combination with other antineoplastic agents or treatments, are provided. Also provided are compositions, and kits containing the composition for affecting the therapy.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: April 7, 2015
    Inventor: Baofa Yu
  • Patent number: 8968699
    Abstract: The invention provides nanodevices or products of manufacture for use as drug delivery vehicles. In one aspect, the invention provides nanodevices or products of manufacture having on-off release mechanisms, e.g., that are “switchable”, or “actuatable” (for example magnetically or ultrasonically switchable), for compounds contained within, e.g., for use as drug delivery nano-vehicles having on-off drug release mechanisms, and their therapeutic applications.
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: March 3, 2015
    Assignee: The Regents of the University of California
    Inventors: Sungho Jin, Seunghan Oh, Karla Brammer, Seong Kong
  • Publication number: 20150050261
    Abstract: The present invention relates to dietary and nutritional supplements comprising various vitamins, minerals and nutrients, including an omega-3 fatty acid of plant-based origin and a folate derivative.
    Type: Application
    Filed: August 15, 2014
    Publication date: February 19, 2015
    Inventors: Chris G. Evenstad, Kelly M. Heimerl, Mike J. McBride, Ronnie Ortiz, Carrol J. Rhead, Sami Yusuf, Michelle B. Zachman
  • Patent number: 8945631
    Abstract: Provided are: a liquid for treatment of Citrus greening disease, which is capable of curing citrus trees with Citrus greening disease; and a treatment method using the liquid. The liquid for treatment of Citrus greening disease contains Fe ions and at least some of the Fe ions are present in the form of Fe2+ ions. This treatment liquid contains a predetermined amount of Fe ions and an acid. Citrus greening disease is able to be cured by spraying the treatment liquid onto leaves of citrus trees infected with Citrus greening disease or by pouring the treatment liquid on the roots of citrus trees infected with Citrus greening disease.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: February 3, 2015
    Assignees: Hiroshima University, Aichi Steel Corporation
    Inventors: Yoshikuni Masaoka, Makoto Usui, Tomoya Matsuyama
  • Publication number: 20140343480
    Abstract: Various agents and additives for cross-linking treatments are identified in disclosed studies. The characteristics of the various agents and additives may be advantageously employed in formulations applied in cross-linking treatments of the eye. In some embodiments, riboflavin is combined with Iron(II) to enhance the cross-linking activity generated by the riboflavin. In other embodiments, cross-linking treatments employ an Iron(II) solution in combination with a hydrogen peroxide pre-soak. In yet other embodiments, 2,3-butanedione is employed to increase the efficacy of corneal cross-linking with a photosensitizer, such as riboflavin. In further embodiments, folic acid is employed in combination with a photosensitizer, such as riboflavin, to enhance cross-linking activity. In yet further embodiments, 2,3-butanedione, folic acid, a quinoxaline, a quinoline, dibucaine, Methotrexate, menadione, or a derivative thereof is applied as a cross-linking agent.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 20, 2014
    Applicant: AVEDRO, INC.
    Inventors: Pavel Kamaev, Marc D. Friedman, Evan Sherr, David Muller
  • Publication number: 20140234437
    Abstract: In one of its aspects, the present invention provides a composition comprising: (i) a non-encapsulated iron salt, and (ii) a carrier comprising digestible edible oil that is a liquid at 20° C. This composition advantageously provides iron in a form that is easily administered to an infant or adult. When taken directly by mouth or added to food or infant formula, the composition has a desirably bland flavor and is easy to consume. Moreover, the high density of iron per unit volume of the composition results in a minimal volume of liquid to be administered. This makes the composition relatively innocuous and easy for infants to consume. Related aspects of the present invention are also described—e.g., uses, articles of manufacture and the like.
    Type: Application
    Filed: July 5, 2012
    Publication date: August 21, 2014
    Inventor: Reinhold Vieth
  • Publication number: 20140186464
    Abstract: The present invention provides a sepsis therapeutic drug useful for prophylaxis and treatment of sepsis. A prophylactic agent and/or a therapeutic agent for sepsis containing 5-aminolevulinic acid (5-ALA) or a derivative thereof or a pharmacologically acceptable salt of 5-ALA or the derivative as an active ingredient is prepared. The prophylactic agent and/or the therapeutic agent preferably contains a metal-containing compound such as ferrous sodium citrate in addition to the ALAs. Preferred examples of the ALAs include ALA; various esters of ALA such as methyl, ethyl, propyl, butyl, and pentyl esters; and hydrochlorides, phosphates, sulfates of ALA and the esters.
    Type: Application
    Filed: August 10, 2012
    Publication date: July 3, 2014
    Applicants: NIHON UNIVERSITY, SBI Pharmaceuticals Co., Ltd.
    Inventors: Kosaku Kinoshita, Katsuhisa Tanjoh, Akihiro Noda, Atsushi Sakurai, Tohru Tanaka, Kiwamu Takahashi, Motowo Nakajima, Fuminori Abe
  • Publication number: 20140186467
    Abstract: A composition comprising at least one penicillin, at least one iron source, and at least one oil, method of making, and method of use thereof are described. Although suitable for many forms and uses, the composition is, in some embodiments, suitable as a pharmaceutical composition, and, in some embodiments, as an antiviral composition capable of restoring T cell count and eradicating HIV virus from patients suffering from HIV/AIDS and other diseases including Tuberculosis.
    Type: Application
    Filed: March 5, 2014
    Publication date: July 3, 2014
    Applicant: BNEERS CORP.
    Inventors: Comfort Wynee DIGGS, Christian SOMUAH, Isaac Dowor JOEMAH, II
  • Publication number: 20130323325
    Abstract: The present invention provides a composition comprising (i) a mixed metal compound containing at least one trivalent metal selected from iron (lll) and aluminium and at least one divalent metal selected from of magnesium, iron, zinc, calcium, lanthanum and cerium, (ii) xanthan gum (iii) at least one of (a) polyvinyl pyrrolidone (b) locust bean gum (c) methyl cellulose wherein the composition has been irradiated with ionising radiation in an amount of at least 4 kGy.
    Type: Application
    Filed: February 3, 2011
    Publication date: December 5, 2013
    Applicant: CYTOCHROMA DEVELOPMENT INC.
    Inventors: Richard Jonathan Applewhite, Maurice Sydney Newton, Alexis John Toft
  • Publication number: 20130309380
    Abstract: Methods of preserving fresh produce with a produce preservative which extends the shelf life of fresh produce, particularly cut fresh produce, and preserves the texture, flavor, appearance, crispness, and color of the fresh produce, particularly the exposed surface of the fresh produce, are provided. The method comprises: providing a solution of produce preservative comprising: water; a preservative cation which is selected from the group consisting of a strontium ion, lithium ion, barium ion, aluminum ion, copper ion, ammonium ion, iron ion, manganese ion, potassium ion, or mixtures thereof; and ascorbate ions, or erythorbate ions; wherein the ascorbate ions or erythorbate ions and the preservative cation are present in an ion ratio of preferably from 0.2:1 to 8:1, more preferably 0.75:1 to 8:1, even more preferably from 1:1 to 4:1, yet more preferably 1.5:1 to 3:1; most preferably 1.1:1 to 2.5:1; and, applying said produce preservative to the produce.
    Type: Application
    Filed: July 26, 2013
    Publication date: November 21, 2013
    Applicant: NatureSeal, Inc.
    Inventors: Chao Chen, Xiaoling Dong, Kenneth James
  • Publication number: 20130295197
    Abstract: Shaped lyocell cellulose articles are provided for binding heavy metal ions and radioactive isotopes thereof. The shaped articles include one or more hexacyanoferrates that are incorporated in a cellulosic matrix and uniformly distributed therein. The shaped articles can be fibers, fibrids, fibrous nonwoven webs, granules, beads, self-supporting films, tubular films, filaments, sponges, foams or bristles. They are useful for water treatment and water decontamination, for metal beneficiation, for treatment of wound with wound dressings, for air and gas filtration and in protective apparel.
    Type: Application
    Filed: March 23, 2013
    Publication date: November 7, 2013
    Inventors: Marcus KRIEG, Martin SELLIN, Michael MOOZ
  • Patent number: 8568792
    Abstract: A mixed metal compound for pharmaceutical use is free from aluminium and has a phosphate binding capacity of at least 30%, by weight of the total weight of phosphate present, over a pH range of from 2-8. The compound is especially useful for treatment of hyperphosphataemia. The metals are preferably iron (III) and at least one of calcium, magnesium, lanthanum and cerium. A metal sulphate for pharmaceutical use is selected from at least one of calcium, lanthanum and cerium sulphate compounds and has a phosphate binding capacity of at least 30% by weight of the total phosphate present, over a pH range from 2-8.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: October 29, 2013
    Assignee: Cytochroma Development Inc.
    Inventors: Norman B Roberts, Maurice Webb, Benjamin J Rankin
  • Patent number: 8568759
    Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: October 29, 2013
    Assignee: W. Neudorff GmbH KG
    Inventor: Diana L. Parker
  • Publication number: 20130259954
    Abstract: Provided are: a liquid for treatment of Citrus greening disease, which is capable of curing citrus trees with Citrus greening disease; and a treatment method using the liquid. The liquid for treatment of Citrus greening disease contains Fe ions and at least some of the Fe ions are present in the form of Fe2+ ions. This treatment liquid contains a predetermined amount of Fe ions and an acid. Citrus greening disease is able to be cured by spraying the treatment liquid onto leaves of citrus trees infected with Citrus greening disease or by pouring the treatment liquid on the roots of citrus trees infected with Citrus greening disease.
    Type: Application
    Filed: December 1, 2011
    Publication date: October 3, 2013
    Applicants: AICHI STEEL CORPORATION, HIROSHIMA UNIVERSITY
    Inventors: Yoshikuni Masaoka, Makoto Usui, Tomoya Matsuyama
  • Publication number: 20130243852
    Abstract: A composition and method for potentiating, sensitizing, and/or amplifying at least one HDAC inhibitor targeting at least one disease in a patient is provided. In one embodiment, the composition is administered to potentiate, sensitize and/or amplify an HDAC inhibitor targeting at least one cancer.
    Type: Application
    Filed: May 9, 2013
    Publication date: September 19, 2013
    Inventor: Robert Sabin
  • Publication number: 20130243720
    Abstract: A pharmaceutical composition comprises a pharmaceutically acceptable ferrous iron compound; an amine polymer or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. Alternatively, a pharmaceutica composition comprises a pharmaceutically acceptable ferrous iron compound and pharmaceutically acceptable carrier, wherein the ferrous iron compound is selected from the group consisting of iron(II) acetate, iron(II) citrate, iron(II) ascorbate, iron(II) oxalate, iron(II) oxide, iron(II) carbonate, iron(II) carbonate saccharated, iron(II) formate, iron(II) sulfate, iron(II) chloride, iron(II) acetylacetonate and combinations thereof. A method of treating a subject with hyperphosphatemia comprises administering to the subject an effective amount of a pharmaceutical composition as described above.
    Type: Application
    Filed: June 27, 2012
    Publication date: September 19, 2013
    Inventors: Chad Huval, Pradeep Dhal, Stephen Randall Holmes-Farley
  • Publication number: 20130230604
    Abstract: Methods of normalizing iron levels, treating iron deficiency and disorders related thereto, such as anemia, as described. Pharmaceutical compositions effective for such treatments are also described.
    Type: Application
    Filed: June 9, 2011
    Publication date: September 5, 2013
    Applicant: Emispere Technologies, Inc.
    Inventors: Gary M. Riley, Parshuram Rath, Michael Novinski
  • Publication number: 20130209577
    Abstract: The present invention relates to compositions of an active pharmaceutical compound or nutritional ingredient with one or more buffering agents between a pH of 1.0 and 6.0, preferably 2.0 and 4.0. The buffering agents are constituted to maintain or reduce the pH of the duodenal fluid in the proximal, mid and distal duodenum. The present invention further relates to methods of improving the absorption of an iron compound or an active pharmaceutical compound within the small intestine. The present compositions and methods improve absorption or bioavailability of the administered compositions.
    Type: Application
    Filed: September 24, 2012
    Publication date: August 15, 2013
    Applicant: Albion International, Inc.
    Inventor: Albion International, Inc.
  • Patent number: 8501243
    Abstract: Methods for treating neoplasm, tumors and cancers, using one or more tumor treating drug carriers, haptens and anticancer drugs, alone or in combination with other antineoplastic agents or treatments, are provided. Also provided are compositions, and kits containing the composition for affecting the therapy.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: August 6, 2013
    Inventor: Baofa Yu
  • Publication number: 20130129810
    Abstract: In accordance with the present disclosure there are provided iron oxide nanoparticles for use in the treatment of non-infectious inflammatory disorders.
    Type: Application
    Filed: April 12, 2011
    Publication date: May 23, 2013
    Applicants: Tel Hashomer Medical Research Infrastructure and Services Ltd., RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Jonathan Leor, Tamar Ben-Mordechai, Shimrit Adutler-Lieber, Rimona Margalit, Inbar Elron-Gross, Yifat Glucksam-Galnoy
  • Patent number: 8440230
    Abstract: The present invention is related to a formulation based on micronized natural calcite mineral consisting of: A. mineral part which is characterized: (i) by the particle size with diameter smaller than 5 ?m, where the distribution of particle size is such that minimum of 10% of particles are with diameter under 900 nm, with total surface of particles greater than 3.2 m2/g, and with total porous volume greater than 0.012 cm3/g, and by composition: (ii) CaCO3, MgCO3, FeCO3, MnCO3, ZnCO3 and SiO2 in mixtures where CaCO3 is presented in amount from 10% to 99% of mineral part; and B. adjuvant selected from the group consisting of: wetting agent, drift-control agent at application by spraying, humic acid salt, amino-acids salts, complex of plant micro-nutrients, vitamin, plant hormone, nitrogen fertilizer, potassium salt, borate salt, molybdate salt, plant extract, chlorophyll, yeast extract, or mixture of these substances; where A. and B. form an aqueous suspension wherein percentage of A. and B.
    Type: Grant
    Filed: January 29, 2008
    Date of Patent: May 14, 2013
    Assignee: Mikro Mineral USA, Inc.
    Inventors: Antonio Lelas, Ivica Cepanec
  • Publication number: 20130108710
    Abstract: Provided is an antimalarial drug which is useful for prevention and treatment of infectious diseases caused by malaria parasites. A preventive and/or therapeutic agent for malaria, which contains, as an active ingredient, 5-aminolevulinic acid (ALA), a derivative thereof, or a pharmacologically acceptable salt thereof, is used.
    Type: Application
    Filed: May 18, 2011
    Publication date: May 2, 2013
    Applicants: THE UNIVERSITY OF TOKYO, SBI PHARMACEUTICALS CO., LTD.
    Inventors: Tohru Tanaka, Satofumi Kawata, Takeo Kohda, Motowo Nakajima, Kiyoshi Kita
  • Patent number: 8389020
    Abstract: Ferrous sulfate and ferrous ammonium sulfate are known to kill moss and liverwort. They impart acidity in the lawn. Moss grows better in an acidic pH. The current invention proposes a formulation of ferrous sulfate or ferrous ammonium sulfate and zero valent iron with lime. Lime neutralizes the acidity produced by the ferrous salt and keeps the pH of the soil at 7 to 7.5. The formulation produces an immediate effect to eradicate moss and also provides a sustained effect over a long period. Another embodiment contains an addition of antimicrobial agents such as benzalkonium chloride, dichlorophen, and didecyldimethyl ammonium chloride to the ferrous sulfate-lime formulation.
    Type: Grant
    Filed: October 2, 2011
    Date of Patent: March 5, 2013
    Assignees: Tara Innovations LLC
    Inventor: Hemant N. Joshi
  • Patent number: 8377483
    Abstract: The object of the present invention is to stabilize bioactivation of iron salt. Said object is attained by adding a magnesium salt to said iron salt. Said iron salt stabilized by said magnesium salt is useful as medicine to treat incurable diseases such as diabetes and growth promoting agent of animals and plants.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: February 19, 2013
    Assignee: I.B.E. Co., Ltd.
    Inventor: Shinji Makino
  • Patent number: 8377482
    Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: February 19, 2013
    Assignee: Warburton Technology Limited
    Inventors: Robert N. Laurie, William A. Smith
  • Publication number: 20130011337
    Abstract: To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) ?-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination. R2R1NCH2COCH2CH2COR3 ??(1) wherein R1 and R2 each independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and R3 represents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Applicant: SBI PHARMACEUTICALS CO., LTD.
    Inventors: Toshihiko KUROIWA, Yoshinaga KAJIMOTO, Takahiro MASUBUCHI, Masahiro ISHIZUKA, Tohru TANAKA
  • Publication number: 20130011495
    Abstract: The present invention relates to an antifungal composition including at least two compounds selected from among the group consisting of cysteine, salicylic acid, iron(II) sulfate and fosetyl-aluminum, as well as to a method for treating a plant, infected or not infected by a pathogen. Specifically, the present invention relates to an antifungal composition for treating vineyards.
    Type: Application
    Filed: July 15, 2010
    Publication date: January 10, 2013
    Inventors: Gabriel Roblin, Estelle Luini
  • Patent number: 8337900
    Abstract: Disclosed are microcapsules and processes of microencapsulation of water soluble or water dispersible compounds by reverse-phase microencapsulation and ways to combine them with other oil soluble or oil dispersible compounds in suitable formulations that yield tiny microcapsules and a very homogeneous distribution of particle size. Multiple combinations of these reverse-phase microcapsules are disclosed, including in combination with normal-phase microcapsules in order to create a Capsule Mixed Suspension (CX) where an outer oil phase or, alternatively, a water phase contains microcapsules of two types: those with a core of water and active ingredients dissolved or dispersed therein, and those with a core of oil and active ingredients dissolved or dispersed therein. Water Dispersible Granules (WDG) and Emulsion Concentrates (EC) and Suspension Concentrates (SC) combinations with the reverse phase microcapsules are also successfully performed.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: December 25, 2012
    Inventors: Victor CasañGiner, Miguel Gimeno Sierra, Barbara Gimeno Sierra
  • Publication number: 20120195974
    Abstract: The invention disclosed in this document concerns controlling mealybugs.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 2, 2012
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Mayank Yadav, Suresh Ramachandran, Sanjoy Kundu
  • Patent number: 8192765
    Abstract: An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and sponges. The composition includes macrosize or submicron particles of silver, platinum with silver and their salts with parabens, oxide, salicylate, acetate, citrate, benzoate and phosphate along with copper and zinc salts of the same.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: June 5, 2012
    Assignee: ICET, Inc.
    Inventor: Shantha Sarangapani
  • Patent number: 8182800
    Abstract: This invention relates to high surface area materials, such as nanoparticles, that are coated with metal ions. These modified nanoparticles have active sites that bind various gases and/or odorous compounds, thereby removing these compounds from a medium such as air or water. Metal ions are adsorbed onto the surface of the nanoparticle and bound strongly to the surface. By selection of the metal ion, specific gaseous compounds and/or odorous compounds can be targeted and removed efficiently and effectively from both aqueous phase and from the air. The modified nanoparticles are useful in numerous article of manufacture for industrial and consumer use.
    Type: Grant
    Filed: August 25, 2009
    Date of Patent: May 22, 2012
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventor: John Gavin MacDonald
  • Patent number: 8168232
    Abstract: The present invention relates to methods and formulations for inhibiting, treating and preventing a malignant cell phenotype, cell, tumor and/or disease. Administration of nitric oxide mimetics, such as low doses, is sufficient to increase, restore or maintain nitric oxide-mediated signaling in cells so that malignant cell phenotypes, cells, tumors and/or diseases are inhibited or prevented. These methods and formulations are particularly useful in treating and preventing cancer in animals.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: May 1, 2012
    Assignee: Queen's University at Kingston
    Inventors: Charles H. Graham, Lynne-Marie Postovit, Michael A. Adams, Jeremy P. W. Heaton
  • Publication number: 20120100119
    Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.
    Type: Application
    Filed: December 8, 2011
    Publication date: April 26, 2012
    Applicant: Momentive Performance Materials Inc.
    Inventors: George A. Policello, Mark D. Leatherman, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
  • Publication number: 20120093910
    Abstract: The present invention relates to a non-hormonal, biocompatible, and biodegradable intravaginal device for the delivery of spermiostatic, spermicidal and anti-infectious agents. The present invention also relates to methods of contraception using such a device, as well as the prevention and treatment of sexually transmitted diseases and vaginal infections through the application of the device.
    Type: Application
    Filed: December 23, 2011
    Publication date: April 19, 2012
    Inventors: Brij SAXENA, Mukul Singh, Sidney Lerner
  • Publication number: 20120064052
    Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.
    Type: Application
    Filed: June 22, 2011
    Publication date: March 15, 2012
    Applicant: Momentive Performance Materials Inc.
    Inventors: George A. Policello, Mark D. Leatherman, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
  • Publication number: 20110305776
    Abstract: The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
    Type: Application
    Filed: November 11, 2009
    Publication date: December 15, 2011
    Applicant: FibroGen, Inc.
    Inventors: Wen-Bin Ho, Lee A. Flippin, Craig Mossman, Eric D. Turtle, Lee R. Wright
  • Publication number: 20110305774
    Abstract: Activation of HIV-1 replication causes oxidative stress, which in turn potentiates HIV-1 replication. The common basis for the compounds of the present invention is: A) the capacity of reactivating HIV-1 from latency, and B) the ability to counteract the cellular machinery which activates in order to limit the effects of oxidative stress. In this way, oxidative stress can be potentiated and a “chain reaction” is sparked. This “chain reaction” induces a more efficient reactivation of HIV-1 from latency and, in some cases, induces selective killing of the infected cells. Actions A) and B) can either be carried out by one drug exerting both effects, or obtained by the combined use of distinct drugs. There are two main cellular machineries counteracting oxidative stress, i.e. the thioredoxin (Trx) thioredoxin reductase (TrxR) system and glutathione. Herein, we present drug strategies capable of exerting action B) by blocking either of the two machineries.
    Type: Application
    Filed: October 29, 2009
    Publication date: December 15, 2011
    Applicant: ISTITUTO SUPERIORE DI SANITA
    Inventors: Andrea Savarino, Marina Lusic, Antonello Mai, Anna Teresa Palamara, Enrico Garaci
  • Publication number: 20110294665
    Abstract: The subject of the present invention is to provide a bioactivator which is useful as a medicine, growth promoting agent for plants and animals, and the like, wherein the bioactive effectiveness of a ferric salt is reinforced and stabilized. One or more kind of vitamin selected from a group consisting of vitamins C, E and K is (are) added to a ferric salt as an anti-oxidizing and bioactivity reinforcing agent, with a magnesium salt being further added as a stabilizer.
    Type: Application
    Filed: December 22, 2009
    Publication date: December 1, 2011
    Applicant: I.B.E. CO., LTD.
    Inventor: Shinji Makino
  • Publication number: 20110251067
    Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.
    Type: Application
    Filed: June 22, 2011
    Publication date: October 13, 2011
    Applicant: Momentive Performance Materials Inc.
    Inventors: George A. Policello, Mark D. Leathermani, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
  • Publication number: 20110244057
    Abstract: The invention provides compositions and methods of treating various conditions, including neurological conditions, with pharmaceutical compositions including a sulfamate (e.g., topiramate) and magnesium.
    Type: Application
    Filed: September 25, 2009
    Publication date: October 6, 2011
    Inventor: Bruce L. Ehrenberg
  • Publication number: 20110195108
    Abstract: An antiviral agent is provided which can inactivate a wide range of viruses. Products that include such an antiviral agent are also provided. The present invention provides an antiviral agent that contains as an active ingredient a particle of at least one kind of iodide composed of iodine and an element shown in Period 4 to Period 6 and Group 8 to Group 15 of a periodic table or at least one kind of monovalent copper compound. The antiviral agent of the present invention can be designed at a higher degree of freedom in terms of its constituents as compared to conventional antiviral agents. In addition, the antiviral agent can readily exhibit and maintain its antiviral activity because it doesn't require any pretreatments or special washing processes.
    Type: Application
    Filed: August 31, 2009
    Publication date: August 11, 2011
    Inventors: Yoshie Fujimori, Tsuruo Nakayama, Tetsuya Sato
  • Patent number: 7994217
    Abstract: Multivitamin/Multimineral supplements are provided for supplementing iron and desirable nutrients in the diet of mammals. The supplements include an iron-amino acid chelate, a form of iron more bioavailable than traditional iron salts. The supplements may further include a pharmaceutically accepted salt form of iron as well as other nutritional vitamins and minerals. The supplements are useful for providing iron for pregnant and lactating females as well as for persons suffering from anemia.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: August 9, 2011
    Assignee: Xanodyne Pharmaceuticals, Inc.
    Inventors: Prasad Nidamarty, William R. Hurd, Roland J. Bydlon, William C. Williams, Michael Dempsey, Amy Erbskorn
  • Publication number: 20110183009
    Abstract: The present invention relates to the field of human health, and more particularly to the treatment of attention deficit/hyperactivity disorder (ADHD) with mazindol. The latter can be administered as monotherapy or in combination with one or more compounds, including psychostimulants, for the indication of ADHD and associated or co-morbid symptoms.
    Type: Application
    Filed: April 5, 2011
    Publication date: July 28, 2011
    Applicant: ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
    Inventor: Eric Konofal
  • Patent number: 7964205
    Abstract: Bait compositions of spinosyns in combination with metal complexones and other mollusicides are provided in an environmentally safe composition that is effective to a treat and/or control a wide spectrum of insect and mollusc pests.
    Type: Grant
    Filed: September 13, 2006
    Date of Patent: June 21, 2011
    Assignee: W. Neudorff GmbH KG
    Inventors: Diana L. Parker, Cameron D. Wilson, George S. Puritch, David S. Almond
  • Patent number: 7935366
    Abstract: A new prophylactic mixture is prepared for the effective decorporation of *Cs, *Sr, *I from affected subjects in the event of an accidental release of the radioisotopes in the environment due to any nuclear accident. The prophylactic mixture comprising: 1) Calcium Potassium Ferrocyanide [CaK2Fe(CN)6] 2) Calcium Iodate, and 3) Calcium Carbonate, can be formulated in the form of a single tablet, capsule or suspension for easy administration to the radiation affected subjects in cases of emergency or nuclear fallout. Also claimed are the compound calcium potassium ferrocyanide (CaK2Fe(CN)6) and the use thereof for decorporation of *Cs in subjects affected by nuclear radiation.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: May 3, 2011
    Assignee: Secretary, Department of Atomic Energy
    Inventors: Dharampal Nandiram Pahuja, Vikram Sarjerao Jagtap, Vinay Ramkrishna Sonawane
  • Patent number: 7931910
    Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: April 26, 2011
    Assignee: W. Neudorff GmbH KG
    Inventor: Diana L. Parker