Elemental Iodine Or Iodine Compound Patents (Class 424/667)
  • Patent number: 6902747
    Abstract: A teat dip composition comprising from about 0.1% to about 2% iodine by weight of the composition on a formulation basis and from about 50% to about 99.9% propylene glycol by weight of the composition on a formulation basis, and a method of using such composition to treat mastitis.
    Type: Grant
    Filed: May 3, 2000
    Date of Patent: June 7, 2005
    Assignee: WestfaliaSurge, Inc.
    Inventors: Charles D. Gradle, Alejandro O. Dee
  • Patent number: 6866869
    Abstract: A liquid antimicrobial composition comprises: (1) a mixture of iodide anions and thiocyanate anions; (2) periodic acid or an alkali metal salt thereof; and (3) optionally, a peroxidase. The composition may be used as a microbicide, disinfectant or for suppressing or killing viruses or spores.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: March 15, 2005
    Assignee: BASF Aktiengesellschaft
    Inventors: Walter Graham Guthrie, Mohammed Shoaib Qureshi, Lawrence Alan Staniforth, Darren Michael Hodgkinson, David Wilson Ashworth
  • Patent number: 6863905
    Abstract: A mixed bed of iodine source/iodine capture resin provides high flow rates that are useful for treatment of water. The ratio of source/capture resin can be adjusted to meet the goals of the system. If insufficient iodine is being provided, the source resin amount can be increased relative to the capture resin. If excess iodine or iodide are found in the treated water, the capture resin amount can be increased relative to the source resin. The release of iodine from the source resin and its effectiveness can be significantly enhanced by using a mixed bed system in which one or both of the source and the capture ion exchange resins have had their exchange sites saturated with the anion of an organic acid such as citrate and/or isocitrate. This significantly increases the amount of iodine released into aqueous solution and enhances the disinfecting power of that iodine.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: March 8, 2005
    Assignee: Shanbrom Technologies, LLC
    Inventor: Edward Shanbrom
  • Patent number: 6855328
    Abstract: An improved antimicrobial composition is described as a liquid concentrate. The liquid concentrate includes a complex resulting from an in-situ reaction of a cation source, an oxidant, a halide source having at least one iodine atom, and a non-mineral acid, or a mixture of a non-mineral acid to about 50% of a hydrophilic solvent by volume.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: February 15, 2005
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, Francis L. Richter, Duane Joseph Reinhardt, Brian R. Leafblad
  • Patent number: 6852340
    Abstract: A biodegradable composition having long term phase and composition stability, and a method for producing both short and long period biocide activity, is used for disinfecting animal husbandry surfaces, in the medical and food industry, and the like. The composition contains propionic acid for pH control, and preferably iodine or an iodine containing compound. The propionic acid combines with ambient ammonia, or ammonia containing compounds arising from fermenting litter and manure to form ammonium propionate, which in turn inhibits or prevents microorganism formation, including mold formation. A surfactant which complexes with the iodine may also be used for spraying onto surfaces, and is effective in the presence of a high organic challenge and hard water.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: February 8, 2005
    Assignee: Preserve International
    Inventors: Gary E. Gaumer, Bruce A. Spielholz
  • Publication number: 20040265240
    Abstract: The present invention is related to a foamable composition of matter comprising iodine, water, a foam adjuvant, a surface-active agent and a gelling agent. This foamable composition, which may be provided in a propellant free foaming device, or alternatively may further comprise a propellant, evolves into foam, which is effective in the topical treatment and prevention of various skin disorders.
    Type: Application
    Filed: April 28, 2004
    Publication date: December 30, 2004
    Applicant: Foamix Ltd.
    Inventors: Dov Tamarkin, Doron Friedman, Meir Eini
  • Publication number: 20040253320
    Abstract: An easily absorbed and well tolerated proportional nutritional supplementation composition and method to be used in patients suffering from deficiency states due to bowel disease that may include malabsorption and inflammatory bowel disease. It is this unique proportional formulation of antacid, calcium, vitamins, minerals and simethicone in lactose free, sorbitol free, gluten free and hypo allergen solution that is the novel invention. This novel invention allows for nutrients to be readily absorbed with little or no side effects that may be experienced when taking conventional supplements. The supplementation contains amounts of vitamins and minerals that are commonly deficient in these states including magnesium, chromium, increased iron, increased folic acid, calcium and fat soluble vitamins.
    Type: Application
    Filed: June 12, 2004
    Publication date: December 16, 2004
    Applicant: Medical Futures Inc.
    Inventor: Pardeep Nijhawan
  • Patent number: 6831103
    Abstract: The present invention relates to a composition for suppressing or ameliorating a symptom accompanying diminished homeostasis, comprising theanine; and a mineral composition comprising theanine and a mineral. According to the present invention, there can be provided a composition for suppressing or ameliorating the above symptoms; and a mineral composition having a reduced peculiar metal taste, of which administration is made easily.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: December 14, 2004
    Assignee: Taiyo Kagaku Co., Ltd.
    Inventors: Tomoko Ueda, Yukiko Nagato, Yukiko Tanaka, Tsutomu Okubo, Kanari Kobayashi, Nobuyuki Aoi, Seiji Shu, Lekh Raj Juneja
  • Patent number: 6814984
    Abstract: The present invention is directed to frozen biocidal compositions. Specifically, the biocidal compositions comprise a frozen aqueous solution of a plurality of ions selected from the group consisting of halide and oxyhalide ions. The frozen biocidal compositions are useful in preserving or extending the shelf-life of perishable articles.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: November 9, 2004
    Assignee: Clean Water International LLC
    Inventors: David C. Rose, Lawrence J. Ventura
  • Patent number: 6777003
    Abstract: An iodine complex concentrate containing (a) from about 0.5 to about 30% by weight of iodine; (b) from about 0.2 to about 14% by weight of an iodide component selected from the group consisting of iodide salt, iodide acid and mixtures thereof; and (c) from about 2% to about 85% by weight of a nonionic sugar surfactant selected from the group consisting of alkyl glucose esters, aldobionamides, gluconamides, glyceramides, glyceroglycolipids, polygydroxy fatty acid amides, alkyl polyglycosides having the general formula I: R1O(R2O)b(Z)a  I wherein R1 is a monovalent organic radical having from about 6 to about 30 carbon atoms; R2 is divalent alkylene radical having from 2 to 4 carbon atoms; Z is a saccharide residue having 5 or 6 carbon atoms; b is a number having a value from 0 to about 12; a is a number having a value from 1 to about 6, and mixtures thereof, all weights being based on the weight of the concentrate.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 17, 2004
    Assignee: Cognis Corporation
    Inventors: Suresh Desai, John Frederick Hessel
  • Patent number: 6764692
    Abstract: A method of treating laminitis in a horse is disclosed, comprising administering to the horse a naturally chelated trace mineral composition; promoting healthy skin, hair and hoof tissue. A method of reducing dietary intake is also disclosed, comprising administering to a horse in need thereof, effective amounts of a naturally chelated trace mineral composition. A method of preparing the chelated trace mineral composition from ocean seabed rock is further disclosed, as well as the chelated trace mineral composition.
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: July 20, 2004
    Inventor: Carlos Cortelezzi
  • Publication number: 20040131707
    Abstract: A new method is described for the treatment of cancer. In one alternative, the method utilizes two main compositions. The first composition is Soma, a healing herb described in the Rig Veda, the sacred scriptures of the Hindus. The second composition is a composite of plant-derived substances and a mineral. When they are administered to cancer patients following the recommended therapeutic regimen, regression of the cancer results. Alternatively, the second composition can be used alone.
    Type: Application
    Filed: September 22, 2003
    Publication date: July 8, 2004
    Inventor: Peter Grandics
  • Publication number: 20040126355
    Abstract: An antimicrobial skin composition comprised of an antimicrobial agent, an alcohol, one or more pH sensitive viscosity builders and water. Preferably, the viscosity builders of the present invention are comprised of pH sensitive methacrylic polymers which are alcohol compatible and have pH controlled water solubility. The composition combines the advantages of an antimicrobial agent and an alcohol, and has a viscosity of from 100 cp to 1,000. This viscosity is sufficiently low for purposes of dispensing and applying the preparation, yet sufficiently high to cause the solution to remain in the area of the wound and not flow away or pool under the patient. The preparation further forms a water-resistant film that is difficult to remove during wound irrigation, but can be easily removed upon completion of the procedure. Finally, the preparation is fast drying so as to take advantage of the fast high initial kill properties of alcohol.
    Type: Application
    Filed: December 30, 2002
    Publication date: July 1, 2004
    Applicant: APLICARE, INC.
    Inventor: David Alan Childers
  • Patent number: 6737083
    Abstract: A reconstituted ocean mixture comprising, sea salt, and the purified product of reverse osmosis of water. A method is provided for treating a pierced area of a person's skin comprising applying to the pierced area a reconstituted ocean water mixture of sea salt and the product of reverse osmosis of water.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: May 18, 2004
    Inventors: Edward Kolos, Jeffrey D. Newsom
  • Publication number: 20040091553
    Abstract: Improved aqueous, ready to use iodine teat dip compositions are provided which are specially formulated for winter time use to permit application to cows teats without freezing while at the same time affording adequate germicidal activity. The compositions include from about 0.01-2% by weight iodine, from about 0.01-3% by weight iodide ion, and from about 35-75% by weight of an additive selected from the group consisting of glycerin and a mixture of at least about 10% by weight glycerin based upon the total weight of the composition and one or more C2-C7 polyhydric alcohols different than glycerin and each containing at least 2 hydroxyl groups, said composition containing no more than about 45% by weight propylene glycol when propylene glycol is one of said polyhydric alcohols. The compositions preferably have free iodine values of from about 1-60 ppm at 25° C. and from about 0.5-20 ppm at 4° C.
    Type: Application
    Filed: November 12, 2002
    Publication date: May 13, 2004
    Applicant: WEST AGRO, INC
    Inventor: Chris Foret
  • Publication number: 20040081707
    Abstract: The invention provides a composition of matter comprising molecular iodine and tetraglycol.
    Type: Application
    Filed: November 19, 2002
    Publication date: April 29, 2004
    Inventors: Uri Wormser, Amnon Sintov
  • Patent number: 6716458
    Abstract: The is invention is directed to a composition useful for assisting in supplying a warm-blooded animal with many of its nutritional needs. More specifically, this invention is directed to a composition whereby many of the vitamins, minerals, amino acids and cofactors are suspended in a matrix which when administered to a mammal provides substantial benefit.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: April 6, 2004
    Inventor: Bryon J. Tarbet
  • Publication number: 20040052778
    Abstract: A liquid antimicrobial composition comprises:
    Type: Application
    Filed: October 10, 2003
    Publication date: March 18, 2004
    Inventors: Walter Graham Guthrie, Mohammed Shoaib Qureshi, Lawrence Alan Staniforth, Darren Michael Hodgkinson, David Wilson Ashworth
  • Patent number: 6696041
    Abstract: The invention relates generally to a method which utilizes iodine as a broad spectrum microbicide wherein the active agent may be applied in nasal passages in the manner of a decongestant type nose spray. The spray is intended particularly for human use. It is to be applied in the event of known or suspected exposure of the individual to common cold virus, flu, or other infective microbial agents including for example, bacteria, viruses, rickettsia, and even mold and fungus. The active agent is based on an iodine solution and may also contain one or more of the following: sodium hypochlorite solution, or a solution of chlorine or hypochlorites plus a salt of chloride, bromide or iodide. Alternatively, the solution may further contain iodine and a bromine solution, or a solution of iodine, bromine plus a salt of chloride, bromide or iodide such as sodium chloride, zinc chloride, sodium bromide, zinc bromide, sodium iodide or zinc iodide.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: February 24, 2004
    Inventor: Richard L. Hansen
  • Publication number: 20040001894
    Abstract: This invention relates to topical compositions and a glove for protection against radiation exposure, such as that due to radiation used in medical procedures.
    Type: Application
    Filed: June 26, 2002
    Publication date: January 1, 2004
    Inventor: Jonathan S. Leibowitz
  • Patent number: 6663902
    Abstract: The present invention relates to a biocidal composition, designed for the generation of chlorine dioxide, comprising at least one iodo-compound having at least one iodine atom and a source of chlorite ions. The molar ration of chlorite ions to iodine atoms is 2 or greater. The composition finds use in a variety of applications including methods of cleaning, sanitizing, deodorizing, and disinfecting various surfaces.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: December 16, 2003
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, David Daniel McSherry, Kim R. Smith, Keith E. Olson
  • Publication number: 20030185902
    Abstract: An improved antimicrobial composition is described as a liquid concentrate. The liquid concentrate includes a complex resulting from an in-situ reaction of a cation source, an oxidant, a halide source having at least one iodine atom, and a non-mineral acid, or a mixture of a non-mineral acid to about 50% of a hydrophilic solvent by volume.
    Type: Application
    Filed: March 28, 2002
    Publication date: October 2, 2003
    Applicant: Ecolab Inc.
    Inventors: Robert D.P. Hei, Francis L. Richter, Duane Joseph Reinhardt, Brian R. Leafblad
  • Patent number: 6627088
    Abstract: Shaped articles which are suitable as biocidal depth-type filters and consist of fibrous materials and particles, embedded therein, of crosslinked crospovidone-iodine or crospovidone-hydrogen peroxide.
    Type: Grant
    Filed: June 28, 1999
    Date of Patent: September 30, 2003
    Assignees: BASF Aktiengesellschaft, Schenk Filterbau GmbH
    Inventors: Jörg Breitenbach, Bernhard Fussnegger, Siegfried Lang, Dietmar Oechsle
  • Publication number: 20030180342
    Abstract: Method for controlling insect pests, pathogenic diseases, and pathogenic nematodes comprising the step of concurrent administration to the locus of an effective amount of iodized lipids or iodine complexes was disclosed.
    Type: Application
    Filed: February 6, 2003
    Publication date: September 25, 2003
    Inventors: Liye Ju, Zhiqiang Ju, Yousheng Duan
  • Publication number: 20030161892
    Abstract: A topical clotting ointment in which cumin in powder form or in oil form is a blood clotter in combination with an unctuous host substance and one or more infection-specific antiseptics and odorants. Method for manufacture includes processing for suspension of the cumin in the host substance and putting it preferably in a squeezable-tube dispenser (7) having an airtight cap (8).
    Type: Application
    Filed: February 27, 2002
    Publication date: August 28, 2003
    Inventor: Connie L. McFarland
  • Publication number: 20030157193
    Abstract: A polymeric composition having antimicrobial properties and a process for rendering the surface of a substrate antimicrobial are disclosed. The composition comprises a crosslinked chemical combination of (i) a polymer having amino group-containing side chains along a backbone forming the polymer, (ii) an antimicrobial agent selected from quaternary ammonium compounds, gentian violet compounds, substituted or unsubstituted phenols, biguanide compounds, iodine compounds, and mixtures thereof, and (iii) a crosslinking agent containing functional groups capable of reacting with the amino groups.
    Type: Application
    Filed: February 5, 2002
    Publication date: August 21, 2003
    Inventors: William F. McDonald, Zhi-Heng Huang, Stacy C. Wright
  • Publication number: 20030152644
    Abstract: Antimicrobial compositions having synergistic combinations of octoxyglycerin and at least one other antimicrobial agent in formulations which are more effective than prior art compositions without causing increased irritation to the skin of the average user. In certain embodiments, skin irritation may be minimized by low concentrations of antimicrobials and/or the presence of soothing compounds such as zinc. Preferred embodiments include combinations of octoxyglycerin, a quaternary compound, and at least one other antimicrobial agent. Without being bound to any particular theory, it is hypothesized that the unexpected antimicrobial effectiveness of combinations of octoxyglycerin may result from an enhancement of the permeability of microbes to antimicrobials caused by octoxyglycerin.
    Type: Application
    Filed: October 23, 2001
    Publication date: August 14, 2003
    Inventors: Shanta Modak, Trupti A. Gaonkar, Lester Sampath
  • Publication number: 20030147971
    Abstract: The invention is a dietary supplement for animals, especially dogs, for treating arthritis and joint discomfort. A biscuit form of the supplement may be in the form of a conventional carrier composition of, for example, typical dog biscuit materials including cereal grains, vegetables or animal meat, fat and by-products. Typically, the biscuit contains about 89-97 weight percent (wt. %) of the conventional carrier composition. Optional vitamins and minerals may also be added to the carrier material, typically in about the 1-5 wt. % range. Importantly, the biscuit of the present invention contains about 3-7 wt. % of an arthritis-treating combination, namely, glucosamine sulfate, vitamin C and an array of intracellular ions namely potassium, sodium and iodine. The glucosamine component is present by weight at approximately the same level as the vitamin C, and at approximately 10 (ten) times the level of the sum of the above-named intracellular ions.
    Type: Application
    Filed: November 18, 2002
    Publication date: August 7, 2003
    Inventor: Andrew Myers
  • Patent number: 6602516
    Abstract: The ability to incorporate iodoform, tetracycline and a combination of iodoform/tetracycline into root canal gutta percha points is described. The iodoform, tetracycline and iodoform/tetracycline combination are bound within the gutta percha points. They act as a reservoir of antimicrobial that is capable of diffusing onto the surface of the gutta percha thereby inhibiting the colonization of bacteria on the gutta percha points and within the root canal system. Tetracycline is capable of coalescing within the dentinal tubules to inhibit long term microbial growth. These medicated gutta percha points are site specific, surface acting antimicrobial gutta percha points. A method of the usage and delivery of amorphous form iodoform gutta percha, iodoform/tetracycline gutta percha, or tetracycline gutta percha within a heated compule with a pressure plunger by delivering the thermo-softened heat labile amorphous form via a pressure extrusion system through a cannula into the prepared root canal system.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: August 5, 2003
    Inventor: Howard Martin
  • Patent number: 6592768
    Abstract: The invention provided relates to the use of polyvinylpyrrolidone-iodine complexes in combination with gelling agents to produce strong disinfectants which not only physically stabilize biohazardous and infectious wastes but also kill pathogens contained in the wastes. The gelling agents include polyacyrlates that are superabsorbents.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: July 15, 2003
    Assignee: BASF Corporation
    Inventors: Anthony Lepore, Siegfried Lang
  • Patent number: 6592890
    Abstract: A wound dressing having anti-infective activity. The wound dressing provides stable and improved formulations of precursors required in generating anti-infective iodine specifically within a wound site where the oxygen tension may be very low. Furthermore, the design of the invention precludes interference by catalase (and other heme proteins.) in competing for hydrogen peroxide where hydrogen peroxide is used as a component of the iodine generating formulation, ensuring more efficient and sustained production of free iodine as a potent anti-infective agent. The invention takes advantage of the physical design of the wound dressing, and the permeation of body fluid into the dressing, which together serve to initiate formation of nascent iodine concomitant with placement of the dressing into, or over, a wound site.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: July 15, 2003
    Assignee: OxiBio, Inc.
    Inventor: Terrence R. Green
  • Patent number: 6565891
    Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among children.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: May 20, 2003
    Assignee: Tsar Health Private Ltd.
    Inventor: Ranjit Kumar Chandra
  • Patent number: 6562378
    Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among adolescents.
    Type: Grant
    Filed: August 16, 2002
    Date of Patent: May 13, 2003
    Assignee: TSAR Health Private Ltd.
    Inventor: Renjit Kumar Chandra
  • Patent number: 6537357
    Abstract: Treatment and preservation of wood, wood fiber products, and porous surfaces with a solution of periodic acid or iodic acid is provided.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: March 25, 2003
    Inventor: Glenn Paul Wampole, Sr.
  • Patent number: 6534075
    Abstract: An antimicrobial and antiviral composition in powder form or in the form of a two part liquid concentrate for washing and sanitizing foods, food surfaces, food ware, process waters, animal quarters, and animal carcasses is described. The composition may also be used to reduce the microbial and viral population on animals; reducing human pathogenic microbes, reducing opportunistic pathogenic microbes on eggs, and treating skin diseases. The composition includes three reactive species which in solution form an oxidizing species, and optionally a food grade acid source. The reactive species include a natural source of a quaternary or protonizable nitrogen compound which is acceptable on foods, an oxidant and a halide source.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: March 18, 2003
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, Kim R. Smith, Polly D. Laugen, Bruce R. Cords, Shaun P. Kennedy
  • Patent number: 6521243
    Abstract: This invention describes non-staining, pharmaceutically useful compositions of ionic complexes made between the cationic polymer chitosan or its derivatives and the small anionic iodine-iodide complex (ICIC's). Unlike previously disclosed ion transfer chitosan iodine complexes, ICIC's were found to possess dramatically higher viscosity than those of each ingredient separately, and instantly form a gel structure that is easily dispersible upon shaking. In addition to their antiseptic power, ICIC's showed better skin biocompatibility than povidone iodine and effectively promoted wound healing.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: February 18, 2003
    Assignee: Pharma C and D, Limited
    Inventor: EmadEldin M. Hassan
  • Publication number: 20030031725
    Abstract: A safe and effective composition that can be taken orally to restore proper balance in pH and trace mineral levels to an individual who exhibits a need for such adjustment. In one embodiment it may be used topically to promote healing of skin lesions and sores. It contains mineral salts and catalyst-altered water in an aqueous solution and may also contain ethanol.
    Type: Application
    Filed: October 1, 2001
    Publication date: February 13, 2003
    Inventor: Ray Carl Massner
  • Publication number: 20030026852
    Abstract: This invention describes a non-aqueous oral composition of molecular iodine in a stabilized hydrophobic environment containing a hydrophobe or combination of hydrophobes for treating different disease states.
    Type: Application
    Filed: March 27, 2001
    Publication date: February 6, 2003
    Applicant: SYMBOLLON CORPORATION
    Inventors: Yongjun Duan, Jack Kessler
  • Patent number: 6506737
    Abstract: An oxidizing species is described herein as a reaction product through an in situ preparation combining a protonizable phosphorus or sulfur compound, and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or powdered media. The oxidizing species can be used to reduce microbial and viral populations on a surface or object or in a body or stream of water. The invention thus finds applications as a bleach, sanitizer, oxidant, or in any other application in which an oxidizing agent can be beneficially used alone or in a formulation.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: January 14, 2003
    Assignee: Ecolab, Inc.
    Inventors: Robert D. P. Hei, Kim Smith
  • Patent number: 6476069
    Abstract: A composition useful as an embolic agent that selectively creates an embolic blockage in the lumen of a blood vessel, duct, fistula or other like body passageways by combining a monomer component and a second component wherein, said monomer component comprises of a alkyl cyanoacrylate monomer and at least one inhibitor agent; and said second component that functions as an opacificant agent and a polymerization retardant.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: November 5, 2002
    Assignee: Provasis Therapeutics Inc.
    Inventors: Robert E. Krall, Charles W. Kerber, Kimberly Knox
  • Patent number: 6476070
    Abstract: A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.
    Type: Grant
    Filed: February 2, 2000
    Date of Patent: November 5, 2002
    Assignee: Provasis Therapeutics Inc.
    Inventors: Robert E. Krall, Charles W. Kerber, Kimberly Knox
  • Publication number: 20020141969
    Abstract: A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.
    Type: Application
    Filed: February 2, 2000
    Publication date: October 3, 2002
    Inventors: Robert E. Krall, Charles W. Kerber, Kimberly Knox
  • Patent number: 6447811
    Abstract: A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic microorganisms such as fungi and bacteria. Preferably the formulation also contains an oil.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: September 10, 2002
    Assignees: Koppert B.V., Campina-Melkunie B.V.
    Inventors: Willem Jacobus Ravensberg, Richard Karel Van der Pas, Klaas Daniel Kussendrager, Johannes Antonius Maria Maas
  • Publication number: 20020119205
    Abstract: This invention describes non-staining, pharmaceutically useful compositions of ionic complexes made between the cationic polymer chitosan or its derivatives and the small anionic iodine-iodide complex (ICIC's). Unlike previously disclosed ion transfer chitosan iodine complexes, ICIC's were found to possess dramatically higher viscosity than those of each ingredient separately, and instantly form a gel structure that is easily dispersible upon shaking. In addition to their antiseptic power, ICIC's showed better skin biocompatibility than povidone iodine and effectively promoted wound healing.
    Type: Application
    Filed: December 22, 2000
    Publication date: August 29, 2002
    Inventor: EmadEldin M. Hassan
  • Patent number: 6440442
    Abstract: The present invention provides a mammalian teat dip composition capable of being used during a mammal's dry period comprising a solution of a film-forming polymer blend comprising a first polymer component which is an organic, solvent-soluble, preformed, thermoplastic polyurethane having no reactive isocyanate groups and a second polymer component which is a hydrophilic poly(N-vinyl lactam), said blend capable of withstanding exposure to water without significant loss of said hydrophilic poly(N-vinyl lactam) in an amount sufficient to form a water-resistant film upon topical application to mammalian skin; and wherein said blend comprises from about 10 to about 80 weight percent of said first polymer in combination with said solvent and from about 1 to about 20 weight percent of said second polymer; and at least one antimicrobial agent in an amount sufficient to treat and protect mammalian skin from infection; wherein said composition is capable of being removed by peeling.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: August 27, 2002
    Assignee: Hydromer, Inc.
    Inventors: Joseph Ehrhard, Michael Eknoian, Alfredo Vinci
  • Patent number: 6436445
    Abstract: An oxidizing species is described herein as a reaction product through an in situ preparation combining a quaternary or protonizable nitrogen compound, an oxidant compound and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or powdered media. The oxidizing species can be used to reduce microbial and viral populations on a surface or object or in a body or stream of water. The invention thus finds applications as a bleach, sanitizer, oxidant, or in any other application in which an oxidizing agent can be beneficially used alone or in a formulation.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: August 20, 2002
    Assignee: Ecolab Inc.
    Inventors: Robert D. P. Hei, Kim R. Smith, Polly D. Laugen, Shaun P. Kennedy
  • Patent number: 6432426
    Abstract: Non-staining topical iodine disinfecting compositions having the ability to inactivate pathogens associated with skin infections or diseases. based upon the presence of molecular iodine in a concentration above at least 15 ppm. Any other iodine species selected from the group consisting of complexed iodine and triiodide may be present with the total of such other iodine species limited to a concentration of less than about 700 ppm so that any visible stain resulting from the application of this composition on the skin will dissipate without leaving any visible skin coloration.
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: August 13, 2002
    Assignee: Symbollon Corporation
    Inventor: Jack Kessler
  • Publication number: 20020102207
    Abstract: A method for chemically marking fish, and particularly salmon to determine migration patterns and spawning locations involves chemically marking salmon taken along select salmon origin, migration patterns or paths, and spawning areas. This avoids stress problems caused by current tagging, or physical marking of the salmon, and the detection system is less expensive and more accurate. Preferred chemical markers are strontium chloride and/or hygroscopic salts, thereof.
    Type: Application
    Filed: February 1, 2001
    Publication date: August 1, 2002
    Inventors: Ronald A. Secor, Leanne M. Secor
  • Patent number: 6410060
    Abstract: This invention relates to the method of non-invasively fortifying eggs with iodine as a dietary supplement without compromising the structural integrity of the egg. The eggs are placed in a solution comprising iodide or iodate salts of alkali or alkali earth metals at an effective concentration for a duration of between a few seconds to a few days. Iodine then passes through the egg shell to the interior of the egg until an adequate internal iodine concentration of iodide or iodate salts is produced.
    Type: Grant
    Filed: May 19, 1998
    Date of Patent: June 25, 2002
    Assignee: Biophile Corporation
    Inventors: Pichit Suvanprakorn, Lerson Tanasugarn, Anusig Limahksohn, Sangsom Sinawat, Prakrom Vuthipongse
  • Patent number: 6395289
    Abstract: The invention discloses a mammalian teat dip for controlling mastitis, a method for preparing the composition and a method of treatment of mammals. The composition contains a film-forming polymer blend, at least one antimicrobial and a sodium bicarbonate buffering agent. The polymer blend contains a solvent-soluble, thermoplastic polyurethane and a hydrophilic poly(N-vinyl lactam). Upon application to mammalian skin, this composition leaves a long-lasting, water-resistant, residual, elastic film that treats and protects mammalian skin from infection.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: May 28, 2002
    Assignee: Hydromer, Inc.
    Inventors: Joseph Ehrhard, Michael Eknoian, Alfredo Vinci