Abstract: The present invention provides devices and methods for stabilizing bicarbonate-based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts—an alkaline bicarbonate concentrate and an acidic concentrate. The alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range.

Abstract: A method and device for treating acute mania or bipolar disorder is disclosed, by transdermal delivery of Li+ at substantially constant rate through the skin via a dermal patch.

Abstract: The present invention describes a novel composition for the treatment of migraine, a common neurovascular syndrome, which can be elicited by functional and/or structural (symptomatic) disorders. This composition comprises taurine, coenzyme Q10 and additionally creatine, L-carnitine, certain vitamins and minerals, carbohydrates, proteins, fats and herbal extracts. Furthermore, the invention describes a method for the treatment of migraine.

Abstract: The invention concerns the use of iso-osmotic saline solutions in particular obtained from sea water, to obtain a medicine designed for a treatment preventing and limiting the release of chemical mediators responsible for causing inflammatory phenomena in the human respiratory tracts.

Abstract: A formulation comprising a phosphate salt, particularly sodium tripolyphosphate for cleansing and treating human skin is disclosed. The formulation provides exfoliating properties useful in gently peeling the skin, as well as sequestering properties for removing harmful metals from the skin. The preferred method for the formulations use is also disclosed.

Abstract: Disclosed are a multipurpose, high-functional, alkaline solution composition, preparation therefor and use thereof as a nonspecific immunostimulator. The composition comprises 1-25 parts by weight of borax (Na2B4O7.10H2O), 10−5-10−4 parts by weight of sodium thiosulfate (Na2S2O3.5H2O), 30-150 parts by weight of potassium carbonate, 30-200 parts by weight of refined sugar (C12H22O11), and 100-200 parts by weight of water, based on 100 parts by weight of sodium metasilicate (Na2SiO3.5H2O). In addition to bringing about an improvement in disease resistance, weight gain rate, crop yield, crop quality, harvest time, the composition shows nonspecific immunostimulating activities, including antibody production and immune enhancement, by activating immune cells, thereby maximizing vaccination effects on malignant viral diseases.

Abstract: What is shown is an animal blood anticoagulant compound useful in the meat packing industry generally, and in slaughterhouse operations, particularly. The anticoagulant is effective when diluted with water at higher dilution ratios than earlier anticoagulants. In some field trials, this anticoagulant was at least as effective as previously known commercial anticoagulants when diluted by an additional 30%. The present anticoagulant preparation concentrate is an aqueous mixture of soft water (55.0%-65.0/%, w/w); tetrasodium ethylene diamine tetraacetate (Na4EDTA) (0.5%-3.0%, w/w); sodium hexametaphosphate (17.0%-24.0%, w/w); citric acid (5.0%-9.0%, w/w); and sodium hydroxide (4.0%-7.0%, w/w) to obtain a balanced pH that provides optimal chelating and anticoagulant activity. Optimal anticoagulant performance has been found to occur in the range of between pH 6.6 and pH 7.2.

Abstract: This invention relates to a method for treating inflammatory symptoms such as burning, redness, itching, swelling and pain which accompany skin disorders other than wounds of the skin. The method comprising topical application of a topical medicinal composition comprising a non-interlinked, particulate bioactive glass mixed with a topical medicinal carrier to the site of the skin disorder.

Abstract: The invention relates to an alimentary integrator constitued by a compound of potassium bicarbonate (KHCO3) and an anti-oxidant agent that comprises D ribose (C6H10O5) and that can comprise ascorbic acid L (C6H8O6).

Abstract: The concentrate is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 microhmo to about 1.2 to 3 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943. The liquid concentrate is applied directly to a skin surface area having a burn or other dermal lesion to protect the area from bacterial contamination.

Abstract: Compositions for inhibiting nematocyst or polar capsule discharge are provided in the form of an effective amount of antihistamine, an effective amount of antihistamine and an effective amount of at least one cation, or an effective amount of at least one cation. The compositions can be in the form of ointments or can be added to the environment surrounding the nematocysts or polar capsules. Methods of inhibiting nematocyst or polar capsule discharge using the compositions of the invention are also provided.

Abstract: Disclosed is both a method and composition for controlling deleterious organisms, such as insects, nematodes and weeds by applying a compound comprised of a liquid medium comprising an azide and an azide stabilizer. The azide can be selected from the group consisting of sodium azide and potassium azide or a combination of the two. The composition provides an effective pesticide, without causing significant harm to the environment. The composition may be applied to soil to control a population of a deleterious organism.

Abstract: An aqueous pourable liquid composition comprising a high concentration of sodium alginate and an alkali metal bicarbonate, wherein the sodium alginate has an average mannuronic acid residue to guluronic acid residue ratio of at least 0.6:1. In addition, an alginate or alginic acid for forming a protective coating on gastrointestinal mucosal tissue, use of and compositions including the same are provided.

Abstract: A process for providing nutrient material for banana and plantain plants, comprising providing a slow release implant containing a banana and plantain nutrient material and implanting the implant into banana or plantain plants whereby the nutrient is slowly released into the plant over a period of time.

Abstract: A permeation enhancer composition is provided for increasing the permeability of skin or mucosal tissue to topically or transdermally administered pharmacologically or cosmeceutically active agents. The composition is comprised of a hydroxide-releasing agent and a lipophilic co-enhancer such as a fatty alcohol, a fatty ether, or a fatty acid ester, including fatty acid esters of polyols such as propylene glycol and glycerol. Also provided are pharmaceutical formulations containing a therapeutically effective amount of an active agent in addition to the aforementioned enhancer composition, methods for administering active agents topically or transdermally with enhanced permeation, and drug delivery systems for application to an individual's skin or mucosal tissue, wherein the systems are formulated so as to contain an active agent to be administered and an effective permeation enhancing amount of an enhancer composition of the invention.

Abstract: A deodorant and antimicrobial dispersion is formed of a deodorant and antimicrobial component, a binder resin and an aqueous or oily liquid medium. The deodorant and antimicrobial component comprises an oxide or hydroxide of an alkaline earth metal, hydrated silica, and a cationic surfactant.

Abstract: A pain relief preparation for use while bathing for soothing and relaxing a user's body. The pain relief preparation for use while bathing includes (A) salts; (B) sodium bicarbonate; (C) an alkaline solution; (D) a bulb; and (E) aromatic seeds for use with water upon a user's body.

Abstract: A method for reducing a risk of carcinogenesis in a subject comprising administering a dose of calcium to the subject that is effective to reduce carcinogenesis. Particularly provided is a method for reducing the risk of recurrence of colorectal adenomas, comprising administering a dose of calcium carbonate effective to reduce the risk of colorectal adenomas. In an example, 1200 mg of elemental calcium (supplied in 3000 mg of calcium carbonate) administered twice daily resulted in decreased risk of recurrent colorectal adenomas in patients with a history of colorectal adenomas.

Abstract: The process involves (a) continuously forming bromine chloride from separate feed streams of bromine and chlorine by maintaining said streams under automatic feed rate control whereby the streams are continuously proportioned to come together to form bromine chloride; (b) continuously forming an aqueous product having an active bromine content of at least 100,000 ppm (wt/wt), a pH of at least 7, and an atom ratio of nitrogen to active bromine greater than 0.93:1 by continuously or intermittently feeding into mixing apparatus separate feed streams of (1) bromine chloride formed in (a), and (2) an aqueous solution of alkali metal salt of sulfamic acid, under automatic feed rate control.

Abstract: The present invention is directed to a method of treating patients with bipolar disorder by administering omega-3 fatty acids.

Abstract: A fertilizer composition, prepared by further diluting an aqueous concentrate and containing an admixture prepared from calcium, potassium, iron, boron and humic acid, when applied to sugar-containing plant leaves infested with sugar-eating, slow-moving, soft-bodied insects, decreases the sugar concentration in such leaves sufficiently to discourage such insects and effectively to rid such leaves of those insects.

Abstract: The present invention provides devices and methods for stabilizing bicarbonate-based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts—an alkaline bicarbonate concentrate and an acidic concentrate. The alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range.

Abstract: A concentrated liquid biocide composition is produced by a continuous process. The process comprises continuously feeding into mixing apparatus (i) bromine chloride and (ii) an aqueous solution of alkali metal salt of sulfamic acid. These are proportioned to produce an aqueous product having an active bromine content of at least 100,000 ppm (wt/wt), and an atom ratio of nitrogen to active bromine from (i) and (ii) greater than 0.93:1. The desired product is withdrawn from the mixing apparatus at a rate sufficient to enable the continuous feeding to be maintained. Thus, the withdrawal of the product can be continuous or intermittent, depending upon the type of mixing apparatus being used.

Abstract: A concentrated liquid biocide composition is produced by a process which comprises continuously or intermittently feeding (i) bromine chloride into mixing apparatus where the bromine chloride contacts (ii) an aqueous solution of alkali metal salt of sulfamic acid. An aqueous product is produced having an active bromine content of at least 100,000 ppm (wt/wt), and an atom ratio of nitrogen to active bromine from (i) and (ii) greater than 0.93:1. The desired product can be withdrawn from the mixing apparatus continuously or intermittently.

Abstract: Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.

Abstract: A composition useful as a dietary supplement for providing potassium, calcium, and citrate is presented, as well as processes for producing the composition, and methods for using the composition as a dietary supplement. Administration of the composition counters bone loss associated with aging or menopause by providing bioavailable calcium and, simultaneously, delivering alkali load. In addition, administration of the composition produces a substantial increase in urinary citrate, which counters kidney-stone formation.

Abstract: A composition for prevention and extermination of plant disease which comprises a biocidal inorganic compound, an amphoteric surfactant, and at least one member selected from the group consisting of a nonionic surfactant and an anionic surfactant. The composition exhibits residual activity for a long period of time without phytotoxicity.

Abstract: This invention provides a liquid antimicrobial composition that is particularly useful as a mouthwash for treating or reducing the risk of dental disease. The composition is prepared by mixing a first solution comprising a water soluble metal chlorite compound with a second solution comprising sodium persulfate and hydrogen peroxide. The resulting composition, containing chlorine dioxide, is preferably used at the time of preparation by applying the composition to the locus where treatment is desired.

Abstract: A novel oral pharmaceutical composition in the form of a stable flocculated suspension in water is described as comprising: megestrol acetate; at least one compound selected from the group consisting of polyethylene glycol, propylene glycol, glycerol, and sorbitol; and a surfactant, wherein polysorbate and polyethylene glycol are not simultaneously present.

Abstract: The invention relates to a mixture for use as wound dressing, which comprises:

Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.

Abstract: Compositions for the treatment and prevention of migraine or stress headaches wherein there is supplied a combination of potassium, magnesium and pyridoxine optionally in association with other nutrients and/or simple analgesics.

Abstract: The present invention relates to animal scent attractants. More particularly, the present invention relates to a composition of matter for amplifying and preserving animal scents. Fox urine, coyote urine, deer urine, elk urine, moose urine, bear urine, rabbit urine, fish oils, and sheep manure are examples of substances which can be used with the present invention.

Abstract: There is provided an antimicrobial composition for combatting infections. The material is a controlled release glass having two or more agents selected from the group consisting of metals, selenium and boron. Preferably the agents are selected from the group consisting of copper, silver, magnesium, zinc, cerium,consisting of copper, silver, magnesium, zinc, cerium, manganese bismuth, selenium and boron. The combinations of copper and silver and of copper and zinc are particularly preferred and exhibit synergist activity. The antimicrobial composition is effective against infections due to Proteus spp.

Abstract: An asepsis disinfectant composition in liquid form having germicidal and biofilm cleansing properties comprising an anti-infective, an antiseptic agent, and an anti-biofilm agent for killing pathogenic and non-pathogenic organisms being in the range of 13.0% to 45.5% by weight of the disinfectant composition; a water purifying agent for acting as a detergent, a sanitizer and a bactericide being in the range of 4.0% to 14.0% by weight of the disinfectant composition; a cleansing agent for acting as an astringent and an abradant in the removal of biofilm from contaminated surfaces, and as a bactericide and fungicide being in the range of 10.0% to 23.0% by weight of the disinfectant composition; an anti-oxidant and stabilizer agent for stabilizing anti-infective and antiseptic agent in the liquid disinfectant composition being in the range of 4.0% to 8.

Abstract: A method of increasing the amount of anagen hair in a human comprising applying an azole or zinc pyrithione, or mixtures thereof to an area of a human where an increase in the amount of anagen hair is desired. Also provided is a method of reducing the shedding of hair in a human comprised of applying an effective amount of an azole or zinc pyrithione to an area of a human where such a reduction is desired. Further provided is a method of increasing the diameter of a hair shaft comprising topically applying an effective amount of an azole to an area of a human where an increase in the diameter is desired.

Abstract: A chemical agent for use in binding to and insolubilizing the solubilized products of fat digestion in order to prevent absorption of fat from the diet.

Abstract: The present invention is directed to a method of inhibiting the growth of disease organisms on and in plants by directly applying an aqueous solution comprising urea and at least one water-soluble salt of a divalent cation and a monovalent anion to the seeds, stems, bark, leaves, seed heads or sub-surface root zones of said plants. The weight percent ratio of urea to divalent cation in these solutions should be from about 0.25-10.0 to 1.0. Preferred divalent cations include those of the alkaline earth metals and the transition metals. Most preferred are calcium, magnesium, zinc, manganese, copper, iron, cobalt, nickel and mixtures thereof. Preferred anions include nitrate, chloride, bromide and mixtures thereof. In more preferred solutions, the ratio of urea to divalent cation is from about 2.0-7.0 to 1.0. Particularly preferred solutions include calcium chloride as the water-soluble salt. Optionally, a second water-soluble salt of a divalent cation and a monovalent anion may be included.

Abstract: An ultraviolet radiation shielding pigment having a high power of shielding of ultraviolet radiation, particularly UV-A, a low cohesive force, and excellent extensibility and adhesiveness as a pigment for cosmetics. A pigment for shielding an ultraviolet radiation which comprises a flaky powder having particle surfaces coated with particles of barium sulfate having an average diameter of 0.1 to 2.0 microns, and with needle crystal particles of zinc oxide having an average major-axis diameter of 0.05 to 1.5 microns, and a process for manufacturing it.

Abstract: Adhesive antimicrobial dental compositions and methods for forming and using compositions are disclosed. The compositions are primarily useful as pulp caps and dentin liners. The composition includes an alkyl methacrylate having an oxyphosphorus group, a polymerization initiator and an antimicrobial agent. The antimicrobial agent can be organohalogens, antibiotics, alkali metal hydroxides, alkaline earth metal oxides and alkaline earth metal hydroxides. The compositions have high dentin tensile bond strength, are stable as a single component or package system, can be polymerized in situ, prevent ingress by microorganisms into an area of a tooth treated with the compositions and can be syringe delivered.

Abstract: A method is provided for destroying a target component, such as hydrocarbons, halogenated hydrocarbons, diethyl-4-nitrophenylphosphate (paraoxon), 2-chloroethyl ethyl sulfide (2-CEES), dimethylmethylphosphonate (DMMP), bacteria such as Bacillus Cereus, Bacillus Globigii, Chlamydia and/or Rickettsiae, fungi and viruses, by contacting the target component with an adsorbent such as MgO, CaO, TiO.sub.2, ZrO.sub.2, FeO, V.sub.2 O.sub.5, V.sub.2 O.sub.3, Mn.sub.2 O.sub.3, Fe.sub.2 O.sub.3, NiO, CuO, Al.sub.2 O.sub.3, ZnO and mixtures thereof wherein the adsorbent contains either reactive atoms selected from the group consisting of halogens and alkali metals stabilized on the surfaces of the adsorbent or ozone and wherein the contacting is conducted at a temperature of -40 to 600.degree. C. for a time period of at least about 4 seconds. The adsorbent may be in the form of solids having a size of about 3 to 20 nanometers or in the form of pellets having a size of at least 1 millimeter.

Abstract: The present invention is directed to a method of treating polycystic ovarian syndrome (PCO) with calcium alone, with vitamin D alone, or with the combination calcium and vitamin D. This invention further provides a method of treating infertility in a woman which comprises administering to the subject an amount of calcium or a derivative thereof effective to treat the infertility. The present invention is also directed to a method of treating irregular menses (oligo/amenorrhea), acne, or hirsutism, insulin resistance, or infertility which comprises administering a combination of calcium or a derivative thereof and vitamin D or a derivative thereof in an amount effective to treat irregular menses (oligo/amenorrhea), acne, or hirsutism, insulin resistance, or infertility.

Abstract: Disclosed herein is a method for treating depression associated with alcoholism in a patient comprising administering to the patient a pharmacologically effective dose of an opioid antagonist, and a pharmacologically effective dose of at least one drug compound selected from the group consisting of a tricyclic antidepressant, an a-typical antidepressant, and lithium.

Abstract: A novel oral pharmaceutical composition in the form of a stable flocculated suspension in water is described as comprising: megestrol acetate; at least one compound selected from the group consisting of polyethylene glycol, propylene glycol, glycerol, and sorbitol; and a surfactant, wherein polysorbate and polyethylene glycol are not simultaneously present.

Abstract: A bolus for supplying a biologically beneficial substance to a ruminant animal, which includes a binder constituted by a rosin matrix, preferably pine rosin, together with a ballast material, such a zinc, with the biologically beneficial substance being dispersed in the binder, so that, in use, the biologically beneficial substance is released by leaching from the non-eroding body of the bolus. A pocket may be included in the body of the rosin bolus, which pocket erodes to release an additional biologically beneficial substance.

Abstract: Therapeutic bath salts for the relaxation of muscles, elimination or reduction of muscle spasms, and for the overall enhancement of a person's mood. The bath salts of the present invention are used as aromatherapy that has both the convenience of a bath and the internal mechanisms of ingested medication. The formula for the composition of the present invention includes a selected amount of magnesium sulfate trihydrate (a hydrated version of epsom salts), lithium chloride, copper gluconate, and essential oils. The oils include rosewood oil, ylang ylang oil, lavender oil and patchouli oil. The oils are provided as scents for use in the prescribed aromatherapy. The user mixes a preselected amount of the crystallized salt or liquid form of the present invention with the bath water. A period of time is allowed to elapse before the user departs the bath. By resting in the tub, the user accrues the combined benefits of external therapy and internal therapy.

Abstract: An attractant composition has been discovered for the control of multiple species of pest arthropods, particularly multiple species of pest ants. The composition, which includes a sugar and a salt or base, and water, attracts both oil-loving and sweet-loving ants and is especially useful with water soluble or suspendable toxicants.

Abstract: A combination of the following active ingredients for treating osteoporosis: (a) a pharmacologically-acceptable alkalinizing potassium salt which produces hydroxyl ions and is thereby capable of reducing the acidity of tissue fluids or urine and which is selected from the group consisting of potassium bicarbonate and potassium salts of carboxylic acids which are transformed to bicarbonate and thus alkalinize in vivo; and (b) a thiazide diuretic.

Abstract: An aqueous recording solution for ink jet according to the present invention contains at least a water-soluble dye, a water-soluble fungusproofing agent and water, and a liquid extracted from at least one type of malvaceae, orchidaceae and aloe is used as the water-soluble fungusproofing agent.

Abstract: Cosmetic/dermatological/pharmaceutical compositions, well suited for the treatment of a variety of mammalian disorders of, for example, the skin, hair and/or mucous membranes, a manifestation of which is an excess in the synthesis and/or in the release of substance P, e.g., for the treatment of cutaneous disorders and sensitive skin, comprise an effective substance P antagonist amount of at least one salt of yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, tin, manganese, or mixture thereof, in a cosmetically/pharmaceutically acceptable medium therefor.