Abstract: A process for treating antigen solutions with an adjuvant is described, in which process a zinc hydroxide/calcium hydroxide gel and, where appropriate, additionally a lecithin and, where appropriate, additionally a polyalphaolefin is added to the antigen solution.
Abstract: A sodium-free composition suitable for use as a substitute for common table salts and a method for preparing the same. The sodium-free composition has as its primary components potassium citrates, calcium citrates, and mixtures of the two components. The material can be prepared by drying and pulverizing crystalline solids derived from a solution containing sufficient citric acid to provide an initial solution pH less than about 3.5, sufficient hydrogen ions to provide a secondary solution pH greater than about 5 and sufficient ions derived from inorganic acids selected from the group consisting of hydrogen chloride, sulfuric acid, phosphoric acid, admixtures thereof to yield a final solution pH between about 3 and about 7.8.
Abstract: Novel methods are provided for treating osteoporosis in humans, comprising administering therapeutic amounts of pharmaceutically-acceptable alkalinizing salts of potassium. The preferred salt is potassium bicarbonate. The methods may also be used to prevent or delay the onset of osteoporosis. Dietary supplementation is a preferred and convenient method of administration.
Type:
Grant
Filed:
October 17, 1989
Date of Patent:
December 15, 1992
Assignee:
The Regents of the University of California
Inventors:
R. Curtis Morris, Jr., Anthony Sebastian
Abstract: Aqueous thiocarbonate solutions are stabilized by the addition of base, sulfide and/or polysulfide, and the stability and safety of the more concentrated solutions containing 1 weight percent or more equivalent CS.sub.2 as a thiocarbonate are achieved as reflected by significant reduction of CS.sub.2 partial pressure in such solutions.
Abstract: The invention is a resorbable, viscous to solid wax for the mechanical staunching of blood on hard body tissue, particularly bones, based on oligomers of glycolic acid and/or lactic acid and derivatives thereof with monofunctional and/or polyfunctional alcohols and/or corresponding carboxylic acids. The new waxes are characterized by containing body-compatible salts of organic and/or inorganic acids which are formed by corresponding reaction of any free carboxyl groups present in the oligomer wax and/or are incorporated in the wax in homogeneous distribution as added salts.
Abstract: The invention is directed to a composition and a method for preparing the same which composition inhibits or destroys unicellular living organisms. The composition is effective as a spermicide and also in combating sexually transmitted diseases and as an antiseptic agent. The composition of the invention comprises lithium and ionic or ionizable fluorine, for example, lithium fluoride. A suitable excipient such as KATHON may also be present. The invention may, for example, comprise lithium fluoride and a spermicidal agent, such as a quaternary ammonium compound, for example, benzalkonium chloride.
Type:
Grant
Filed:
September 20, 1988
Date of Patent:
November 5, 1991
Assignee:
Atlantic Pharmaceutical Products Ltd.
Inventors:
Pierre Bourbon, Pierre Lagny, Pierre Billot
Abstract: A skin conditioning composition in the form of a lotion applied to the skin has bicarbonate ions in an emollient carrier and pH in excess of 7.0. The composition is formed by the combining of a diluent with thickener/stabilizer and a hemectant with a fat agent and emulsifier which brings the pH to 7.0 and above 7.0 to which is added an aqueous solution of sodium bicarbonate. A quantity of mineral oil which serves as an emollient is a preferred addition to the final mixture.
Abstract: The mineral composition is useful for treatment of blood acidosis, peritoneal ascites and anemia. It is a combination of particulate wood ash and calcium carbonate.
Abstract: Peritoneal dialysis solution with usual electrolyte composition in physiological amounts and with galactose as osmotically active substance in an amount of 1-70 g/l.
Abstract: Oil-in-water emulsions containing polyvinyl alcohol, surfactant and a salt with improved freeze-thaw and elevated temperature storage stability.
Type:
Grant
Filed:
June 5, 1989
Date of Patent:
March 5, 1991
Assignee:
Sandoz Ltd.
Inventors:
Ralston Curtis, Howard R. Brownell, Steven C. Papanu
Abstract: An aqueous cathartic solution and method for bowel cleansing is provided. The solution is isotonic, has a minimum buffering effect on human blood and is substantially inorganic. The aqueous solution includes about 3.5 grams/liter of sodium sulfate; about 4.82 grams/liter of magnesium sulfate; about 1.9 grams/liter of sodium bicarbonate; about 3.85 grams/liter of sodium chloride; about 0.746 grams/liter of potassium chloride. To cleanse the bowel between 3.0 and 4.0 liters of the solution are usually administered to a patient.
Abstract: Silicic acid modulates (i.e. enhances or inhibits) adenylate cycloase activity. This effect appears to be a general one, inasmuch as the modulation has occurred in all tissues studied. The results suggest that silicic acid can be used in human and veterinary medicine to modulate hormone or neurotransmitter response. The results also indicate that silicic acid can be used to prevent, treat, or delay the onset of calcium-related bone disease, or to improve bone strength in an vertebrate having a bone strength less than desired.
Abstract: This invention relates to compositions comprising electrolytes dissolved in a buffer which is painless when administered by irrigation.This invention also relates to compositions comprising a local anesthetic such as lidocaine, procaine, mepivacaine or marcaine, dissolved in a buffered solution containing salts which do not cause pain when the solutions are administered. The compositions are useful for administration as painless local anesthetics and painless irrigation-anesthetizing solutions for human and animal use. The invention further relates to methods for painless irrigation of wounds and of inducing painless local anesthesia comprising administering an effective amount of the compositions of this invention to an animal.
Abstract: Halophors of a complex of bromine or iodine, a tertiary amide, e.g., dialkylformamide or dialkyl acetamide, and a halide, e.g., alkali metal or alkaline earth metal bromide or iodide, are described. The alkyl groups of the tertiary amide are typically lower alkyl groups, i.e., groups containing from 1 to 4 carbon atoms. Also described are solid biocidal compositions, e.g., fumigants, of particulate, free-flowing inert amorphous siliceous carrier having at least a biocidal amount of halophor admixed with said carrier.
Type:
Grant
Filed:
January 16, 1986
Date of Patent:
January 16, 1990
Assignee:
PPG Industries, Inc.
Inventors:
Paritosh M. Chakrabarti, Roger A. Crawford, Robert H. Juda
Abstract: Halophors, e.g., bromophors, comprising a complex of sulfone, e.g., sulfolane, halide ion, e.g., sodium bromide, and halogen, e.g., bromine, are described. Solid, free-flowing halophor compositions of the aforesaid complex and an amorphous siliceous carrier are also described.
Type:
Grant
Filed:
January 16, 1986
Date of Patent:
July 4, 1989
Assignee:
PPG Industries, Inc.
Inventors:
Robert H. Juda, Paritosh M. Chakrabarti, Roger A. Crawford