Alkali Metal Or Alkaline Earth Containing Patents (Class 424/722)
  • Patent number: 5232690
    Abstract: A process for treating antigen solutions with an adjuvant is described, in which process a zinc hydroxide/calcium hydroxide gel and, where appropriate, additionally a lecithin and, where appropriate, additionally a polyalphaolefin is added to the antigen solution.
    Type: Grant
    Filed: March 6, 1991
    Date of Patent: August 3, 1993
    Assignee: Behringwerke Aktiengesellschaft
    Inventors: Dieter Bernhardt, Joachim Hilfenhaus
  • Patent number: 5213838
    Abstract: A sodium-free composition suitable for use as a substitute for common table salts and a method for preparing the same. The sodium-free composition has as its primary components potassium citrates, calcium citrates, and mixtures of the two components. The material can be prepared by drying and pulverizing crystalline solids derived from a solution containing sufficient citric acid to provide an initial solution pH less than about 3.5, sufficient hydrogen ions to provide a secondary solution pH greater than about 5 and sufficient ions derived from inorganic acids selected from the group consisting of hydrogen chloride, sulfuric acid, phosphoric acid, admixtures thereof to yield a final solution pH between about 3 and about 7.8.
    Type: Grant
    Filed: January 23, 1991
    Date of Patent: May 25, 1993
    Inventor: Morris Sheikh
  • Patent number: 5171583
    Abstract: Novel methods are provided for treating osteoporosis in humans, comprising administering therapeutic amounts of pharmaceutically-acceptable alkalinizing salts of potassium. The preferred salt is potassium bicarbonate. The methods may also be used to prevent or delay the onset of osteoporosis. Dietary supplementation is a preferred and convenient method of administration.
    Type: Grant
    Filed: October 17, 1989
    Date of Patent: December 15, 1992
    Assignee: The Regents of the University of California
    Inventors: R. Curtis Morris, Jr., Anthony Sebastian
  • Patent number: 5165920
    Abstract: Aqueous thiocarbonate solutions are stabilized by the addition of base, sulfide and/or polysulfide, and the stability and safety of the more concentrated solutions containing 1 weight percent or more equivalent CS.sub.2 as a thiocarbonate are achieved as reflected by significant reduction of CS.sub.2 partial pressure in such solutions.
    Type: Grant
    Filed: March 27, 1991
    Date of Patent: November 24, 1992
    Assignee: Union Oil Company of California
    Inventors: James A. Green, II, Donald C. Young
  • Patent number: 5143730
    Abstract: The invention is a resorbable, viscous to solid wax for the mechanical staunching of blood on hard body tissue, particularly bones, based on oligomers of glycolic acid and/or lactic acid and derivatives thereof with monofunctional and/or polyfunctional alcohols and/or corresponding carboxylic acids. The new waxes are characterized by containing body-compatible salts of organic and/or inorganic acids which are formed by corresponding reaction of any free carboxyl groups present in the oligomer wax and/or are incorporated in the wax in homogeneous distribution as added salts.
    Type: Grant
    Filed: July 25, 1989
    Date of Patent: September 1, 1992
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Johann-Friedrich Fues, Wolfgang Ritter
  • Patent number: 5063064
    Abstract: The invention is directed to a composition and a method for preparing the same which composition inhibits or destroys unicellular living organisms. The composition is effective as a spermicide and also in combating sexually transmitted diseases and as an antiseptic agent. The composition of the invention comprises lithium and ionic or ionizable fluorine, for example, lithium fluoride. A suitable excipient such as KATHON may also be present. The invention may, for example, comprise lithium fluoride and a spermicidal agent, such as a quaternary ammonium compound, for example, benzalkonium chloride.
    Type: Grant
    Filed: September 20, 1988
    Date of Patent: November 5, 1991
    Assignee: Atlantic Pharmaceutical Products Ltd.
    Inventors: Pierre Bourbon, Pierre Lagny, Pierre Billot
  • Patent number: 5037648
    Abstract: A skin conditioning composition in the form of a lotion applied to the skin has bicarbonate ions in an emollient carrier and pH in excess of 7.0. The composition is formed by the combining of a diluent with thickener/stabilizer and a hemectant with a fat agent and emulsifier which brings the pH to 7.0 and above 7.0 to which is added an aqueous solution of sodium bicarbonate. A quantity of mineral oil which serves as an emollient is a preferred addition to the final mixture.
    Type: Grant
    Filed: January 22, 1990
    Date of Patent: August 6, 1991
    Inventor: Evelyn S. Joiner
  • Patent number: 5035888
    Abstract: The mineral composition is useful for treatment of blood acidosis, peritoneal ascites and anemia. It is a combination of particulate wood ash and calcium carbonate.
    Type: Grant
    Filed: November 6, 1989
    Date of Patent: July 30, 1991
    Inventor: Tadataka Hara
  • Patent number: 5011826
    Abstract: Peritoneal dialysis solution with usual electrolyte composition in physiological amounts and with galactose as osmotically active substance in an amount of 1-70 g/l.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: April 30, 1991
    Assignee: Fresenius AG
    Inventors: Volker Steudle, Volker Bartz
  • Patent number: 4997642
    Abstract: Oil-in-water emulsions containing polyvinyl alcohol, surfactant and a salt with improved freeze-thaw and elevated temperature storage stability.
    Type: Grant
    Filed: June 5, 1989
    Date of Patent: March 5, 1991
    Assignee: Sandoz Ltd.
    Inventors: Ralston Curtis, Howard R. Brownell, Steven C. Papanu
  • Patent number: 4975286
    Abstract: An aqueous cathartic solution and method for bowel cleansing is provided. The solution is isotonic, has a minimum buffering effect on human blood and is substantially inorganic. The aqueous solution includes about 3.5 grams/liter of sodium sulfate; about 4.82 grams/liter of magnesium sulfate; about 1.9 grams/liter of sodium bicarbonate; about 3.85 grams/liter of sodium chloride; about 0.746 grams/liter of potassium chloride. To cleanse the bowel between 3.0 and 4.0 liters of the solution are usually administered to a patient.
    Type: Grant
    Filed: May 15, 1989
    Date of Patent: December 4, 1990
    Assignee: E-Z-EM, Inc.
    Inventor: Herbert G. Hechter
  • Patent number: 4954448
    Abstract: Silicic acid modulates (i.e. enhances or inhibits) adenylate cycloase activity. This effect appears to be a general one, inasmuch as the modulation has occurred in all tissues studied. The results suggest that silicic acid can be used in human and veterinary medicine to modulate hormone or neurotransmitter response. The results also indicate that silicic acid can be used to prevent, treat, or delay the onset of calcium-related bone disease, or to improve bone strength in an vertebrate having a bone strength less than desired.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: September 4, 1990
    Assignee: Nelson Research & Development Company
    Inventors: Karl E. Wiegand, Robert K. Rude
  • Patent number: 4938970
    Abstract: This invention relates to compositions comprising electrolytes dissolved in a buffer which is painless when administered by irrigation.This invention also relates to compositions comprising a local anesthetic such as lidocaine, procaine, mepivacaine or marcaine, dissolved in a buffered solution containing salts which do not cause pain when the solutions are administered. The compositions are useful for administration as painless local anesthetics and painless irrigation-anesthetizing solutions for human and animal use. The invention further relates to methods for painless irrigation of wounds and of inducing painless local anesthesia comprising administering an effective amount of the compositions of this invention to an animal.
    Type: Grant
    Filed: July 17, 1987
    Date of Patent: July 3, 1990
    Inventors: Robert E. Hustead, David R. Hustead
  • Patent number: 4894241
    Abstract: Halophors of a complex of bromine or iodine, a tertiary amide, e.g., dialkylformamide or dialkyl acetamide, and a halide, e.g., alkali metal or alkaline earth metal bromide or iodide, are described. The alkyl groups of the tertiary amide are typically lower alkyl groups, i.e., groups containing from 1 to 4 carbon atoms. Also described are solid biocidal compositions, e.g., fumigants, of particulate, free-flowing inert amorphous siliceous carrier having at least a biocidal amount of halophor admixed with said carrier.
    Type: Grant
    Filed: January 16, 1986
    Date of Patent: January 16, 1990
    Assignee: PPG Industries, Inc.
    Inventors: Paritosh M. Chakrabarti, Roger A. Crawford, Robert H. Juda
  • Patent number: 4844899
    Abstract: Halophors, e.g., bromophors, comprising a complex of sulfone, e.g., sulfolane, halide ion, e.g., sodium bromide, and halogen, e.g., bromine, are described. Solid, free-flowing halophor compositions of the aforesaid complex and an amorphous siliceous carrier are also described.
    Type: Grant
    Filed: January 16, 1986
    Date of Patent: July 4, 1989
    Assignee: PPG Industries, Inc.
    Inventors: Robert H. Juda, Paritosh M. Chakrabarti, Roger A. Crawford