Alkali Metal Or Alkaline Earth Containing Patents (Class 424/722)
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Patent number: 5876763Abstract: A rehydration formulation which enhances a subjects ability to quickly recover from dehydration. The rehydration formulation includes a glycerol solution combined with a carbohydrate or sodium to produce a desired result. The glycerol solution combats the ill-effects of dehydration by increasing plasma osmolality thereby preventing loss of osmotic stimulus to thirst and enabling full rehydration to occur.Type: GrantFiled: May 26, 1998Date of Patent: March 2, 1999Assignee: University of New MexicoInventors: Paul Montner, Dan Stark
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Patent number: 5866168Abstract: Dermatological/pharmaceutical compositions, well suited for the therapeutic treatment of and/or alleviation of pain associated with at least one of the skin disorders, zona, poszoster, scald or burns, demodicidosis, skin ulcer, fibrosis, hypertrophic cicatrization and/or acne rosacea, comprise an effective substance P antagonist amount of at least one salt of yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, tin, zinc, manganese, cobalt, barium, strontium, or mixture thereof, in a dermatologically/pharmaceutically acceptable medium therefor.Type: GrantFiled: October 28, 1996Date of Patent: February 2, 1999Assignee: Societe L'Oreal S.A.Inventors: Olivier De Lacharriere, Lionel Breton
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Patent number: 5851556Abstract: The invention relates to the use of a salt of an alkaline-earth metal in a cosmetic, pharmaceutical, veterinary and/or dermatological composition for treating, in particular, sensitive skins. It relates, in addition, to the use of a salt of an alkaline-earth metal for preventing and/or combating rosacea and/or skin irritation and/or dartre and/or pudic erythema and/or dysesthetic sensation and/or sensation of inflammation and/or pruritus of the skin and/or of the mucous membranes. The salt is in particular strontium nitrate or chloride.Type: GrantFiled: April 10, 1996Date of Patent: December 22, 1998Assignee: Societe L'Oreal S.A.Inventors: Lionel Breton, Olivier De Lacharriere
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Patent number: 5840278Abstract: An aqueous nasal spray formulation contains a vitamin component, a mineral component, a aloe vera in a water based solvent. The vitamin component contains Vitamin C, Rose Hips, Acerola, Lemon Bioflavanoids, Hesperidin, Rustin and Vitamin B.sub.6. The mineral component contains potassium, calcium, magnesium, zinc and manganese. In the formulation, the vitamin component accounts for 25-40% by volume of the formulation, the mineral component is from 11-12% by volume and the aloe vera is from 8-12% by volume of the formulation.Type: GrantFiled: February 20, 1997Date of Patent: November 24, 1998Inventor: Thomas Coleman
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Patent number: 5840770Abstract: This invention provides an immunoenhancement or immune-potentiation therapy comprising administration of potassium, insulin, glucose and, optionally, thyroid, a cholinergic agent and bicarbonate. Therapeutic compositions comprising the above components in appropriate dosages are also provided.Type: GrantFiled: January 28, 1997Date of Patent: November 24, 1998Assignee: Hill Medical CorporationInventor: Albert Fay Hill
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Patent number: 5840320Abstract: A method of increasing the bulk density and improving the water-dispersibility, oil sorption capacity, and body dirt and oil removability by compacting and/or shearing a magnesium rich calcium montmorillonite clay. In an optional embodiment of the present invention, silica gel, sodium silicate, acrylic polymers and copolymers, carboxy methyl cellulose, or other materials capable of providing lubricity to the surface of the clay crystals is added to the clay, prior to shearing, to enhance the compaction and/or shearing process and further increase the bulk density of the clay. The clay is sheared in an extruder, pug mill or California-type pellet mill when the clay includes about 20% to about 45%, preferably about 25% to about 40% by weight water, based on the dry weight of the clay.Type: GrantFiled: October 25, 1995Date of Patent: November 24, 1998Assignee: AMCOL International CorporationInventor: Ira Edgar Odom
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Patent number: 5833969Abstract: An aqueous cosmetic composition containing uric acid in a stably solubilized state together with 0.01 to 1.3% by weight of one or more amphoteric surfactants selected from the group consisting of (a) lauric acid amide propyl betaine, (b) alkyl carboxymethyl hydroxyethyl imidazolinium betaine, (c) coconut oil fatty acid amide propylmethylaminoacetic acid betaine, (d) sodium salt of coconut oil fatty acid acyl carboxymethyl hydroxyethyl ethylenediamine, (e) lauryl dimethylaminoacetic acid betaine and (f) coconut oil alkyl betaine, an alkali and water. The composition is adjusted to pH equal to or higher than pK.sub.1 of uric acid with the alkali to solubilize uric acid. A method for stably solubilizing uric acid in an aqueous cosmetic composition is also disclosed.Type: GrantFiled: July 30, 1997Date of Patent: November 10, 1998Assignee: Yamahatsu Sangyo Kaisha, Ltd.Inventors: Yoshio Tsujino, Akiko Ogata, Kazuyo Tomura
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Patent number: 5814222Abstract: A process for enriching a liquid with oxygen by introducing the liquid into an oxygen enriching vessel, subdividing the liquid, subjecting the interior of the vessel to an oxygen pressure of at least about 20 psi, conducting the introduced water in a substantially flowing contact with the oxygen, and recovering the water under oxygen pressure when it is to be bottled. The process is carried out in oxygen enriching apparatus having an oxygen enriching vessel, a number of horizontal trays vertically spaced apart from each other and having a central opening, a liquid supply tube ranging into the interior of the enriching vessel through the central openings, means for discharging liquid from the tube onto a tray, an oxygen supply source for providing the oxygen to the vessel, and a liquid outlet for the removal of the oxygenated liquid. The liquids oxygenated by the invention are used in various aerobic and therapeutic processes.Type: GrantFiled: May 1, 1995Date of Patent: September 29, 1998Assignee: Life International Products, Inc.Inventors: Zoltai Maria nae Zelenak, Laszlo Berzsenyi, Frank Abramoff
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Patent number: 5785990Abstract: A feed fortifier and enhancer for preruminant, bovine calves comprising animal plasma as well as other ingredients. The feed fortifier and enhancer may be mixed with any liquid feed to be fed to preruminant calves.Type: GrantFiled: July 10, 1995Date of Patent: July 28, 1998Assignee: Merrick's, Inc.Inventor: Jana S. Langrehr
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Patent number: 5776503Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: July 24, 1997Date of Patent: July 7, 1998Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5770233Abstract: An object of the present invention is to provide an infusion preparation set (a container filled with infusion liquids) useful for preparation of an infusion liquid containing sugars, amino acids, electrolytes, a fat emulsion and vitamins. The present invention is constituted by the use of a container having two compartments which are separated from each other by a separation means, which contains an infusion liquid comprising a fat emulsion, sugars, fat-soluble vitamins and specified water-soluble vitamins in the first compartment and an infusion liquid comprising amino acids, electrolytes and other specified water-soluble vitamins in the second compartment. An infusion preparation containing sugars, amino acids, electrolytes, a fat emulsion and vitamins can be obtained easily and aseptically upon use, by simply removing a separation means and mixing the infusion liquids included in the first and second compartments.Type: GrantFiled: April 21, 1995Date of Patent: June 23, 1998Assignee: The Green Cross CorporationInventors: Takae Kido, Shigeo Ii, Shun-ichi Abe, Kazumasa Yokoyama
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Patent number: 5766640Abstract: A method for simultaneously treating osteoporosis and hypertension in the same individual by the administration of pharmaceutically acceptable alkalinizing potassium salts, such as potassium bicarbonate, preferably in the form of a dietary supplement.Type: GrantFiled: June 5, 1995Date of Patent: June 16, 1998Assignee: The Regents of the University of CaliforniaInventors: R. Curtis Morris, Jr., Anthony Sebastian
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Patent number: 5756107Abstract: Topical formulations comprising an anti-irritant amount of aqueous-soluble lithium (Li.sup.+) or potassium (K.sup.+) cation, and methods for using the same to inhibit skin irritation, are disclosed.Type: GrantFiled: December 21, 1994Date of Patent: May 26, 1998Assignee: Cosmederm TechnologiesInventors: Gary Scott Hahn, David Orel Thueson
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Patent number: 5698230Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: March 24, 1997Date of Patent: December 16, 1997Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5698231Abstract: A pesticide solution comprising a spray bottle including a mixture of lemon juice, cleaning soda, liquid soap and water incorporated into a spray bottle to be used to combat roaches, ants, fleas and the like without risking harm to humans and household pets.Type: GrantFiled: August 30, 1996Date of Patent: December 16, 1997Inventors: Thomas J. Felder, Jr., Edward R. Felder
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Patent number: 5696099Abstract: Topical Preparations for the treatment of acne and acneiform dermatitis containing as active principle therapeutically active quantities of N,N'bis (2-hydroxyethyl) nonandiamide together with dermatansulfate lithium salt, having molecular weight ranging from 2000 to 7000, combined with suitable excipients and/or diluents.Type: GrantFiled: April 18, 1994Date of Patent: December 9, 1997Assignee: Lifegroup S.p.A.Inventors: Francesco della Valle, Roberto Cerini, Gabriella Calderini
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Patent number: 5688527Abstract: New lysine derivatives containing a fluoroalkyloxycarbonyl or fluoroalkylsulphonyl group of formula:COOH--CH(NH.sub.2)--(CH.sub.2).sub.4 --NH--X--(CH.sub.2).sub.n --Rin which n ranges from 0 and 4, X represents a divalent COO or SO.sub.2 group and R represents a linear or branched perfluoroalkyl radical having from 4 to 20 carbon atoms, salts thereof, and mixtures of the derivatives and the salts. A process for the preparation of these derivatives, salts, and mixtures and use of such derivatives, salts, and mixtures, especially in cosmetics. Compositions, especially cosmetic compositions, comprising the derivatives, salts, and mixtures.Type: GrantFiled: January 23, 1996Date of Patent: November 18, 1997Assignee: L'OrealInventors: Thierry Bordier, Michel Philippe
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Patent number: 5670176Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: April 4, 1995Date of Patent: September 23, 1997Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5646240Abstract: Provided by the present invention are novel diguanamine derivatives, led by 2,5/2,6-bis(4,6-diamino-1,3,5-triazin-2-yl)-bicyclo[2.2.1]heptanes and 1,3/1,4-bis(4,6-diamino-1,3,5-triazin-2-yl)-cyclohexanes, and derivatives thereof, applications of these compounds in fields such as adhesives and paints, utilization of these compounds in flame-retarding, thermal stabilization and compatibilization methods of resins, thermosetting molding compositions and thermosetting expansion-molding compositions making use of these compounds, as well as polymeric microspheres also using these compounds. These compounds are expected to find wide spread industrial utility as various excellent properties can be obtained by using them.Type: GrantFiled: March 21, 1996Date of Patent: July 8, 1997Assignee: Mitsui Toatsu Chemicals, Inc.Inventors: Tetsuya Oishi, Jin Suzuki, Kouhei Ohkawa, Hiroshi Ono
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Patent number: 5585118Abstract: The present invention is directed to methods in which a lithium source and a choline source act synergistically to reduce or eliminate the symptoms associated with bipolar disorder.Type: GrantFiled: June 2, 1995Date of Patent: December 17, 1996Assignee: Brigham and Women's HospitalInventor: Andrew L. Stoll
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Patent number: 5580377Abstract: A plate barium sulfate is described, which has a particle size of from 1 to 100 .mu.m or from 5 to 150 .mu.m, wherein neither a sulfide nor a soluble barium salt is detected by an analysis method based on the Japanese Cosmetics Material Standard. The process of the plate barium sulfate is also described.Type: GrantFiled: June 7, 1995Date of Patent: December 3, 1996Assignee: Sakai Chemical Industry Co., Ltd.Inventors: Koichi Ohtsu, Hirobumi Yoshida, Noriaki Sato
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Patent number: 5571535Abstract: A composition and method for use in treating topical Herpes Simplex 1 infections of the skin, in which the composition comprises a mixture of at least 0.5% by weight of the following ingredients: an alkali metal carbonate; an alkali metal phosphate; and an alkali metal hypochlorite, in a pharmaceutically acceptable topical carrier in the form of a powder, a cream, or a lotion, and the method comprises applying such compositions to the skin at the site of the infection.Type: GrantFiled: November 30, 1990Date of Patent: November 5, 1996Inventors: Marianne Flowers, Basilio Tavares
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Patent number: 5512213Abstract: A treatment for stabilizing an isothiazolone compound comprising adding to the compound a stabilizing amount of a metal salt, wherein the cation of the metal salt is an alkali metal, and the anion is selected from the group consisting of acetate, citrate, phosphate and borate.Type: GrantFiled: March 1, 1995Date of Patent: April 30, 1996Assignee: Betz Laboratories, Inc.Inventor: Donald J. Paterson
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Patent number: 5510335Abstract: An exercise regimen which enhances exercise endurance and performance. The regimen includes pre-exercise hydration with a glycerol solution combined with hydration during exercise with a glycerol based solution to prolong hydration effects. The first pre-exercise glycerol solution regimen begins 2 hours prior to exercise and ends 1/2 hour before exercise begins. The hydration during exercise regimen combines glycerol with a carbohydrate and sodium to prolong fluid retention.Type: GrantFiled: January 6, 1995Date of Patent: April 23, 1996Assignee: University of New MexicoInventors: Paul Montner, Thomas W. Chick, Dan Stark, Marvin L. Riedesel
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Patent number: 5505922Abstract: An anesthetic pharmaceutical combination comprising the combination of a local anesthetic and lithium ions present in an amount effective to lower the amount of the local anesthetic necessary to achieve equivalent anesthetic effect in a patient and a method of use of the anesthetic pharmaceutical combination.Type: GrantFiled: February 24, 1995Date of Patent: April 9, 1996Assignee: University of Maryland at BaltimoreInventors: Paul D. Thut, Michael D. Turner
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Patent number: 5498426Abstract: Liquid antacid compositions for neutralizing stomach acid in humans and other animals comprising: an alkaline earth carbonate salt; and alkali metal phosphate salt; an alkali metal bicarbonate salt; and other excipients.Type: GrantFiled: October 3, 1994Date of Patent: March 12, 1996Assignee: The Procter & Gamble CompanyInventors: Robert L. Wilson, Sara A. Ubelhor, William A. Cruz
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Patent number: 5498428Abstract: Novel methods are provided for treating hypertension in humans which comprise administering therapeutic amounts of pharmaceutically-acceptable non-halide salts of potassium. Preferred salts are potassium bicarbonate and potassium phosphate. The methods may also be used to lower the blood pressure of normotensive individuals. Dietary supplementation is a preferred and convenient method of administration.Type: GrantFiled: January 10, 1994Date of Patent: March 12, 1996Assignee: The Regents of the University of CaliforniaInventors: R. Curtis Morris, Jr., Anthony Sebastian
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Patent number: 5496566Abstract: A method of installing in a building a suspension containing paramagnetic susceptible elements consisting essentially of:(A) providing in a non-metallic container 5-12 pounds of a composition consisting essentially of (i) 30-99 wt % of a carbonate or a mixture of two or more carbonates selected from the group consisting of magnesium carbonate, calcium carbonate, strontium carbonate, barium carbonate and mixtures thereof, wherein the carbonate or mixture of carbonates are in powder form, (ii) 1-70 wt % of activated carbon in powder form, (iii) 0.Type: GrantFiled: July 19, 1994Date of Patent: March 5, 1996Inventors: Raymond C. Crippen, Carleton T. Miller
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Patent number: 5496569Abstract: A method for simultaneously treating osteoporosis and hypertension in the same individual by the administration of pharmaceutically acceptable alkalinizing potassium salts, such as potassium bicarbonate, preferably in the form of a dietary supplement.Type: GrantFiled: April 2, 1993Date of Patent: March 5, 1996Assignee: The Regents of the University of CaliforniaInventors: R. Curtis Morris, Jr., Anthony Sebastian
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Patent number: 5482720Abstract: This invention provides an encapsulated co-micronized bicarbonate salt powder composition which is a blend of crystalline ingredients having a particle size between about 0.1-30 microns. The composition is produced by mill co-micronization of a crystalline bicarbonate ingredient and a crystalline inorganic compound ingredient having a Mohs hardness value between about 3-7, and then surface coating the particles with a polymer. A blend of crystalline particles such as sodium bicarbonate and zinc oxide is free-flowing and essentially free of agglomerated solids after co-micronization, and the discrete crystalline particles are coated with a polymer to form a present invention encapsulated co-micronized bicarbonate salt powder composition.Type: GrantFiled: October 11, 1994Date of Patent: January 9, 1996Assignee: Church & Dwight Co., Inc.Inventors: Richard T. Murphy, Wolfgang R. Bergmann
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Patent number: 5482717Abstract: The invention is a resorbable, viscous to solid wax for the mechanical staunching of blood on hard body tissue, particularly bones, based on oligomers of glycolic acid and/or lactic acid and derivatives thereof with monofunctional and/or polyfunctional alcohols and/or corresponding carboxylic acids. The new waxes are characterized by containing body-compatible salts of organic and/or inorganic acids which are formed by corresponding reaction of any free carboxyl groups present in the oligomer wax and/or are incorporated in the wax in homogeneous distribution as added salts.Type: GrantFiled: March 10, 1994Date of Patent: January 9, 1996Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Johann-Friedrich Fues, Wolfgang Ritter
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Patent number: 5466470Abstract: This invention provides a co-micronized bicarbonate salt composition which is a blend of ingredients having a particle size between about 0.01-1.0 micron. The composition is produced by mill co-micronization of a crystalline bicarbonate ingredient and a crystalline inorganic compound ingredient having a Mohs hardness value between about 3-7. A co-micronized blend such as sodium bicarbonate and zinc oxide is free-flowing and essentially free of agglomerated particles.Type: GrantFiled: May 25, 1994Date of Patent: November 14, 1995Assignee: Church & Dwight Co., Inc.Inventor: M. Stephen Lajoie
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Patent number: 5449522Abstract: This invention provides an immunoenhancement or immunepotentiation therapy comprising administration of potassium, insulin, glucose and, optionally, thyroid, a cholinergic agent and bicarbonate. Therapeutic compositions comprising the above components in appropriate dosages are also provided.Type: GrantFiled: August 24, 1993Date of Patent: September 12, 1995Inventor: Albert F. Hill
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Patent number: 5443835Abstract: This invention provides a dry blend pesticide composition which contains a fungicidal bicarbonate salt ingredient, and a spreader-sticker ingredient which is a crystalline clathrate complex of a urea constituent and a normally liquid spreader sticker constituent such as a nonionic surfactant. In a preferred embodiment all of the composition ingredients are water-soluble, and the composition is readily dispersible in an aqueous medium to form a sprayable pesticide solution.Type: GrantFiled: September 30, 1993Date of Patent: August 22, 1995Assignee: Church & Dwight Co. Inc.Inventor: Anthony E. Winston
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Patent number: 5439674Abstract: A hair set retaining cosmetic material comprising a polymer complex prepared by (1) reacting an amino group containing polysiloxane having the formula:A.sub.m R.sub.3-m SiO(R.sub.2 SiO).sub.x (QRSiO).sub.y SiR.sub.3-n A.sub.nwherein A is selected from the group consisting of a hydroxyl group, an alkoxy group, and an amino group containing alkylether group; R is selected from the group consisting of an alkyl group having 1 to 18 carbon atoms and a hydroxyl group; Q represents an amino containing alkyl group; m and n each represent a number of 0 to 3; x represents a number of 30 to 400; and y represents a number of 1 to 30 with an anionic group containing polymer; and (2) neutralizing a reaction product of step (1) with an alkaline compound to a neutralization ratio of 60-150%.Type: GrantFiled: January 14, 1994Date of Patent: August 8, 1995Assignee: OSi Specialties, Inc.Inventors: Isao Noda, Suguru Tsubaki
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Patent number: 5417987Abstract: A method for enhancing the effect of a toxicant such as chlorine or potassium on bivalve molluscs such as zebra mussels. Application of serotonin or a serotonin agonist in low concentrations inhibits the mussels' ability to close their valves to protect themselves from the effect of any toxicants in the water. Thus administering serotonin or a serotonin agonist for a period of time, followed by administering a toxicant, substantially enhances the effect of the toxicant on the zebra mussels. Thus less of the toxicant need be administered to control zebra mussels. The concentration of serotonin needed to enhance toxicant control of exotic zebra mussels has been found to be at or below the threshold of serotonin activity on native bivalves, at least those native to the lower Mississippi River. Furthermore, serotonin is naturally degraded rapidly by aquatic microorganisms.Type: GrantFiled: September 16, 1993Date of Patent: May 23, 1995Assignees: Board of Supervisors of Louisiana State University, Agricultural and Mechanical CollegeInventors: Thomas H. Dietz, John W. Lynn, Harold Silverman
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Patent number: 5415878Abstract: Lithium titanate is made by heating to a temperature of at least 715 C., powder form lithium carbonate and titanium dioxide while mixing, for instance in a rotary kiln. The product is formulated into extended release oral pharmaceutical compositions. Lithium ions are released by zero order rate characteristics from the compositions. The composition can have increased density to extend retention in the stomach. The compositions are used for treatment of manic depressive illness.Type: GrantFiled: April 21, 1993Date of Patent: May 16, 1995Assignee: London School of Pharmacy Innovations LimitedInventors: John M. Newton, Jing Qui, Paul O'Brien
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Patent number: 5413798Abstract: A process for treating bovine pericard tissue to increase resistance to biological degradation by wet-chemical processing, The wet-chemical processing consists essentially of: (i) separating any adherent fat and basal membrane from the tissue; (ii) contacting the tissue with an aqueous, alkaline solution of sodium hydroxide, potassium hydroxide, lithium hydroxide or sodium carbonate to swell the tissue; (iii) contacting the swollen tissue with an aqueous sodium chloride solution to control the swelling; (iv) contacting the tissue with a solution of a metal-ion complexing agent with a pH in excess of 11; and (v) contacting the tissue with an aqueous buffer solution having a pH of 4.5 to 6.0. Each of steps (ii)-(v) is followed by a water rinse. The pericard tissue is then dried and sterilized.Type: GrantFiled: April 6, 1994Date of Patent: May 9, 1995Assignee: B. Braun Melsungen AktiengesellschaftInventors: Edmund Scholl, Helmut Waldert, Helmut Beyer
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Patent number: 5407794Abstract: Peripheral blood lymphocytes displayed a plurality of sizes and colors when exposed first to a fixative solution of C.I. basic blue 141, then to an aqueous alkaline solution of the same dye and subsequently treated with a neutral HEPES buffer solution containing small but effective amounts of various metal compounds. As confirmed with purified lymphocyte subpopulations obtained with a cell sorter, T helper cells (CD4) were small and their nuclei and cytoplasm stained deep blue. T cytotoxic/suppressor cells (CDS) were larger than T helper cells, their nuclei stained pale green or blue green and their cytoplasm contained a cluster of magenta colored granules. Used in the process described, basic blue 141 provides means of identifying and differentiating CD4 and CD8 cells under the ordinary light microscope without using monoclonal antibodies or fluorescence.Type: GrantFiled: February 9, 1994Date of Patent: April 18, 1995Assignee: Cytocolor Inc.Inventor: Lawrence Kass
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Patent number: 5403921Abstract: An exercise regimen which enhances exercise endurance and performance. The regimen includes pre-exercise hydration with a glycerol solution combined with hydration during exercise with a glycerol based solution to prolong hydration effects. The first pre-exercise glycerol solution regimen begins 2 hours prior to exercise and ends 1/2 hour before exercise begins. The hydration during exercise regimen combines glycerol with a carbohydrate and sodium to prolong fluid retention.Type: GrantFiled: April 30, 1993Date of Patent: April 4, 1995Assignee: University of New MexicoInventors: Paul Montner, Thomas W. Chick, Dan Stark, Marvin L. Riedesel
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Patent number: 5376362Abstract: This invention provides a homogeneous antiperspirant cosmetic stick or roll-on product containing a deodorant ingredient which consists of particles that contain multiple fine crystallites of a bicarbonate compound encapsulated with a hydrophilic polymer coating that lowers the relative density of the particles and improves the dimensional stability of the cosmetic product.Type: GrantFiled: April 27, 1993Date of Patent: December 27, 1994Assignee: Church & Dwight Co., Inc.Inventors: Richard T. Murphy, M. Stephen LaJoie
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Patent number: 5366722Abstract: The invention relates to improved contrast media containing non-ionic contrast agents, e.g. non-ionic iodinated X-ray contrast agents, the improvement being achieved by incorporation of sodium at 20-60 mM/l.Type: GrantFiled: November 24, 1993Date of Patent: November 22, 1994Assignee: Nycomed Imaging ASInventors: Torsten Almen, Laars B.ANG..ANG.th, Audun Oksendal
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Patent number: 5360782Abstract: Aqueous thiocarbonate solutions are stabilized by the addition of base, sulfide and/or polysulfide, and the stability and safety of the more concentrated solutions containing 1 weight percent or more equivalent CS.sub.2 as a thiocarbonate are achieved as reflected by significant reduction of CS.sub.2 partial pressure in such solutions. Also, deposit formation in irrigation systems delivering such thiocarbonates, such as drip emitters and sprinkler heads, is reduced or eliminated with minor amounts of sodium hexametaphosphate.Type: GrantFiled: October 22, 1993Date of Patent: November 1, 1994Assignee: Union Oil Company of CaliforniaInventors: Donald C. Young, James A. Green, II
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Patent number: 5356625Abstract: A microgranular preparation having a core of biologically active material that is encapsulated by a water soluble film that is covered by an enteric coating of either an alkali soluble, acid insoluble polymer or a high molecular weight polymer whose structure is substituted with or contains windows of fatty acids or other material capable of being solubilized by intestinal juices. Useful for protecting pH sensitive and other biologically active materials from inactivation or contact with the stomach or rumen, and releasing the same in active form in the intestinal tract, particularly the duodenum.Type: GrantFiled: February 27, 1989Date of Patent: October 18, 1994Assignee: Enzacor Properties LimitedInventor: Thomas K. S. Ying
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Patent number: 5332580Abstract: Aqueous thiocarbonate solutions are stabilized by the addition of base, sulfide and/or polysulfide, and the stability and safety of the more concentrated solutions containing 1 weight percent or more equivalent CS.sub.2 as a thiocarbonate are achieved as reflected by significant reduction of CS.sub.2 partial pressure in such solutions. Also, deposit formation in irrigation systems delivering such thiocarbonates, such as drip emitters and sprinkler heads, is reduced or eliminated with minor amounts of sodium hexametaphosphate.Type: GrantFiled: November 25, 1992Date of Patent: July 26, 1994Assignee: Union Oil Company of CaliforniaInventors: Donald C. Young, James A. Green, II
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Patent number: 5308623Abstract: The invention is a resorbable, viscous to solid wax for the mechanical staunching of blood on hard body tissue, particularly bones, based on oligomers of glycolic acid and/or lactic acid and derivatives thereof with monofunctional and/or polyfunctional alcohols and/or corresponding carboxylic acids. The new waxes are characterized by containing body-compatible salts of organic and/or inorganic acids which are formed by corresponding reaction of any free carboxyl groups present in the oligomer wax and/or are incorporated in the wax in homogeneous distribution as added salts.Type: GrantFiled: February 27, 1992Date of Patent: May 3, 1994Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Johann-Friedrich Fues, Wolfgang Ritter
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Patent number: 5288492Abstract: A decongestant composition and method are provided for treatment of symptoms associated with respiratory disorders. The composition in the form of an aqueous solution which comprises aloe vera, castor oil, sodium metasilicate and calcium chloride as the essential active components. The decongestant can be topically applied to the nasal or bronchial passages from dispensers containing spray means or inhalation mist means.Type: GrantFiled: November 13, 1992Date of Patent: February 22, 1994Inventor: Michael A. Morris
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Patent number: 5281424Abstract: Novel methods are provided for treating hypertension in humans which comprise administering therapeutic amounts of pharmaceutically-acceptable non-halide salts of potassium. Preferred salts are potassium bicarbonateGOVERNMENT SUPPORTThis invention was made with Government support under Grant No. M01-RR0079 awarded by the National Institutes of Health. The Government has certain rights in this invention.Type: GrantFiled: May 29, 1991Date of Patent: January 25, 1994Assignee: The Regents of the University of CaliforniaInventors: R. Curtis Morris, Jr., Anthony Sebastian
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Patent number: 5256424Abstract: Aqueous thiocarbonate solutions are stabilized by the addition of base, sulfide and/or polysulfide, and the stability and safety of the more concentrated solutions containing 1 weight percent or more equivalent CS.sub.2 as a thiocarbonate are achieved as reflected by significant reduction of CS.sub.2 partial pressure in such solutions.Type: GrantFiled: May 31, 1991Date of Patent: October 26, 1993Assignee: Union Oil Company of CaliforniaInventors: James A. Green, II, Donald C. Young
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Patent number: 5236496Abstract: Paste compositions comprising from 20 to 60% by weight of an alkaline-earth metal hydroxide selected from the group consisting of calcium hydroxide, magnesium hydroxide, strontium hydroxide, and the mixture threreof; from 20 to 60% by weight of a polyhydric alcohol; from 0.5 to 5% by weight of an alkali-soluble cellulose derivative; and from 5 to 20% by weight of water based on the total weight of the composition are disclosed. Also disclosed are a method for preparing the same; a medicament useful for pulpotomy, medicament for stimulating the formation of osteoid scar; and a method for pulpotomy and a method for osteosis comprising the step of applying the above composition.Type: GrantFiled: June 13, 1991Date of Patent: August 17, 1993Assignee: Showa Yakuhin Kako Co., Ltd.Inventors: Mutsumi Shibuya, Satomi Ishii