Abstract: An environmentally responsive Paecilomyces lilacinus microbead and its preparation method and application are provided. The Paecilomyces lilacinus microbead includes a capsule core and a capsule wall; wherein, in the capsule core, Paecilomyces lilacinus spore powder, a vegetable oil, glucose, peptone, a cellulose nanofiber, sodium citrate, and a surfactant are combined to form an emulsifiable capsule core; and in the capsule wall, chitosan, gelatin, polyvinyl alcohol, glycerol, and water are combined to form a water-responsive shell. The environmentally responsive Paecilomyces lilacinus microbeads can stimulate the dissolution of polyvinyl alcohol in the shell according to the moisture content in the soil, so that the water in the soil flows into the microbeads. The cellulose nanofibers in the microbeads absorb water and expand, blocking the holes in the shell, resulting in the inability of spores to flow out.
Type:
Grant
Filed:
December 24, 2020
Date of Patent:
November 9, 2021
Assignee:
Jiangxi Huawei Technology Co., Ltd.
Inventors:
Liqiang Zou, Tong Wu, Guizhong Chen, Wei Liu
Abstract: Embodiments of the disclosure concern methods and compositions related to manipulation of the microbiome in an individual having at least one social behavior deficit. In particular embodiments, an individual has at least one social behavior deficit and was born from a mother who during pregnancy was obese, overweight, or on a high-fat diet during pregnancy or carries mutations associated with neurodevelopmental disorders. In specific embodiments, the individual having at least one social behavior deficit is provided an effective amount of Lactobacillus reuteri for the improvement of at least one symptom of a social behavior deficit.
Type:
Grant
Filed:
April 15, 2017
Date of Patent:
October 5, 2021
Assignee:
Baylor College of Medicine
Inventors:
Mauro Costa-Mattioli, Shelly Alexandra Buffington
Abstract: Described are probiotic compositions for human oral consumption comprising Veillonella bacteria. In some aspects, the probiotic compositions further comprise a salt of nitrate (NO3?) and/or a salt of nitrite (NO2?). In other aspects, the probiotic compositions further comprise a salt of nitrite (NO2?) and a natural source of nitrate. In certain embodiments, the probiotic compositions additionally comprises a polyphenol. Also described herein are methods of enhancing generation of bioactive nitrogen oxides in a human subject, of treating or preventing a gastrointestinal disorder in a human subject, of enhancing athletic performance in a human subject, and of enhancing administration of nitrite or nitrate in a human subject, wherein the human subject is administered the probiotic compositions described herein.
Abstract: The present disclosure relates to a mixture of bacteria belonging to at least six or seven different and specific bacterial species preferably for use in preventing or treating gastro-intestinal disorders. Preferably, the mixture of bacteria are grown together in a fermenter prior to administering the mixture to a subject in order to prevent or treat the disorder.
Abstract: Provided herein are novel Lactobacillus fermentum strains, NRRL B-67059 or NRRL B-67060, compositions containing the NRRL B-67059 or NRRL B-67060 strains, and fermented dairy products and bioactive compounds prepared using the NRRL B-67059 or NRRL B-67060 strains. Also provided are methods of modulating the immune system of a subject.
Type:
Grant
Filed:
December 23, 2016
Date of Patent:
July 27, 2021
Assignee:
Dairy A Day Inc.
Inventors:
Belinda Vallejo Galland, Aarón Fernando González Córdova, José Antonio Feregrino Quezada, Juan Carlos Feregrino Quezada
Abstract: The present invention relates to the use of a galactooligosaccharide composition for preventing or reducing the risk of developing metabolic syndrome.
Abstract: The present disclosure relates to the use of autologous fecal samples obtained from a subject for use in prevention and/or treatment of microbial dysbiosis in the gastrointestinal tract in said subject and to related pharmaceutical compositions for oral administration. The disclosed autologous fecal samples are useful for treatment of microbial dysbiosis in the gastrointestinal tract associated with medical treatment and/or various indications, including chronic disease and infectious disease, for example Clostridium difficile infection.
Type:
Grant
Filed:
January 19, 2018
Date of Patent:
June 29, 2021
Assignee:
BACTAVIVA AB
Inventors:
Hans Peter Torsten Ekre, Lars Georg Engstrand, Ola Gosta Flink, Otto Sten Gunnar Skolling
Abstract: A media supplement for culturing anaerobic bacteria is provided which comprises a filtrate of eilluent from a chemostat vessel in which a target bacterial ecosystem has been culnn-ed. Methods of using the supplement for culturing or isolating anaerobic microbial strains or cormmmities, particularly anaerobic bacteria from the human gut, are also provided.
Abstract: Disclosed herein are compositions and methods for using human-derived Janthinobacterium lividum. Compositions improve skin health. Methods may include applying human-derived Janthinobacterium lividum over a host or host area, such as skin or mucosa, to minimize the presence of one or more microbes, maximize therapeutic effects, and/or improve health. A method to minimize a pathogenic microbe may include applying to a surface a composition including human-derived Janthinobacterium lividum and an acceptable carrier. Compositions and methods may include a prebiotic to maximize growth and/or metabolites. Compositions and methods may include human-derived Janthinobacterium lividum metabolites, such as violacein, prodigiosin, indole-3-carboxaldehyde, and lantibiotics, and/or other Postbiotics.
Type:
Grant
Filed:
May 27, 2020
Date of Patent:
June 22, 2021
Assignee:
DermBiont, Inc.
Inventors:
Robert M. Brucker, Xuecheng Zhang, Ida Lister, Sanjay Jain
Abstract: Described herein are methods and compositions for the treatment of skin conditions associated the dysbiosis. Further described herein is the use of metabolites for treatment of dysregulated microbiota in a subject. Such metabolites can be produced by microorganisms present in a higher abundance in the skin of healthy subjects as compared to the skin of a subject having dysbiosis of the skin. In addition, compositions and methods provided herein describe the use of metabolites as part of a combination therapy.
Abstract: Bifidobacterium longum AH1362 (NCIMB 41715) produces a polysaccharide and increases energy excretion. The strain is used in the prevention or treatment of obesity and obesity-related metabolic syndrome.
Type:
Grant
Filed:
December 9, 2016
Date of Patent:
April 13, 2021
Assignee:
PrecisionBiotics Group Limited
Inventors:
Barry Kiely, Eileen Frances Murphy, Selena Healy
Abstract: The invention relates to compositions and methods for treating inflammatory diseases and disorders in a subject in need thereof. In certain aspects, the invention relates to immunogenic compositions (e.g., vaccines) to diminish the number or pathogenic effects of one or more bacteria associated with the development or progression of an inflammatory disease or disorder.
Type:
Grant
Filed:
August 28, 2015
Date of Patent:
February 23, 2021
Assignee:
Yale University
Inventors:
Richard Flavell, Noah Palm, Marcel De Zoete
Abstract: The present invention is intended for the use of a probiotic composition comprising Bifidobacterium animalis subs. lactis (B. lactis), Bifidobacterium longum and Lactobacillus rhamnosus, in particular the strains B. lactis CECT 8145, B. longum ES1 CECT 7347 and/or L. rhamnosus CECT 8361, in the treatment and/or prevention of psoriasis outbreaks or psoriasis.
Inventors:
Vicente Manuel Navarro López, Ana Adela Ramírez Boscá, José Manuel Pérez Orquín, Daniel Ramón Vidal, Salvador Genovés Martínez, María Empar Chenoll Cuadros, Francisco Manuel Codoñer Cortés
Abstract: A method for preventing and/or treating vitamin B12 deficiency is taught. The method comprises administering a composition comprising pseudovitamin B12-producing bacteria, optionally in conjunction with mucin-degrading and/or propionate-producing bacteria, to a subject in need thereof. The method is particularly suitable for administration to subjects suffering from vitamin B12 deficiency due to metformin treatment for type-2 diabetes, and to subjects having undergone bariatric surgery.
Abstract: Endophytic microbial strains as biocatalysts isolated from fresh plant samples, compositions, and methods of use thereof to enhance the growth and/or yield of a plant in the presence of reduced synthetic phosphate fertilizers are provided. Endophytic microbial strains serve as biocatalysts to solubilize mineral-P and mineralize organic-P otherwise unavailable to plants for their nutritional phosphate needs. Thus defined, biocatalysts, will serve to replace synthetic phosphate fertilizers. Also provided are materials and methods for inoculating plants with these biocatalysts at carefully selected inoculum densities to reliably reduce the amount of synthetic phosphate fertilizer by 50% thus accomplishing obtaining optimal yields in technically and cost-effective manner.
Abstract: A natural product for improving health and reducing the risk of death due to dangerous diseases comprises a presence of figs and Acetobacter pasteurianus.
Abstract: A formulation for vaginal administration comprising an effective amount of a composition of dried Lactobacillus cells and boric acid, with a carrier. The composition can include one or more antioxidants. Optionally, the composition is in a unit dosage form. Also provided are methods for making and using the composition.
Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide for use in preventing and/or treating constipation and/or in improving stool consistency/frequency in an infant or a young child.
Type:
Grant
Filed:
March 4, 2016
Date of Patent:
November 3, 2020
Assignee:
Societe des Produits Nestle S.A.
Inventors:
Norbert Sprenger, Dominique Brassart, Delphine Egli
Abstract: Provided are Christensenella intestinihominis and an application thereof, specifically, use of Christensenella intestinihominis in treating and preventing obesity and related diseases thereof. Also provided are a composition for treating and preventing obesity and related diseases thereof, comprising compositions of drugs, drinks, food, or animal feed, and a method for reducing weight and/or blood lipid.
Type:
Grant
Filed:
September 6, 2016
Date of Patent:
October 20, 2020
Assignee:
BGI SHENZHEN
Inventors:
Yuanqiang Zou, Wenbin Xue, Mei Lv, Liang Xiao, Xiaoping Li, Jinghong Yu, Chuan Liu
Abstract: A spore-forming Bacillus species, and more particularly, a Bacillus subtilis strain identified as MB40 is provided. Compositions comprising the MB40 strain, methods of making products comprising the same, and methods of using the same are also provided.
Type:
Grant
Filed:
October 14, 2019
Date of Patent:
September 29, 2020
Assignee:
BIO-CAT, INC.
Inventors:
Christopher S. Penet, Sebhat Gebrechristos, Caroline Helen Best, Deborah S. Winetzky, Robert Daniel Little, Jr., Jessica Spears, Christopher Schuler
Abstract: A synthetic composition for use in treating or improving one or more emotion and/or mood disorders in a patient, characterised in that the composition contains an effective amount of one or more neutral human milk oligosaccharides, is disclosed.
Type:
Grant
Filed:
October 28, 2016
Date of Patent:
September 22, 2020
Assignee:
GLYCOM A/S
Inventors:
Bruce McConnell, Emma Elison, Louise Kristine Vigsnæs
Abstract: The therapeutic use of bacteria, specifically but not only lactobacilli, which produce indole-3-aldehyde, or directly of indole-3-aldehyde itself, is proposed as a means of prevention and treatment of immune dysreactive disorders in which the hyper-inflammatory or autoimmune component represents the basic element.
Abstract: This invention relates to processes for the preparation of antiparasitic isoxazoline compounds enriched in an enantiomer using quinine-based chiral phase transfer catalyst. The invention also relates to novel quinine-based phase transfer catalysts and to a toluene solvent form of the isoxazoline compound of the invention.
Type:
Grant
Filed:
November 7, 2018
Date of Patent:
August 25, 2020
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Abstract: Provided are a new Paenibacillus sp. strain, the deposit number of which is CGMCC No. 8333, and a method for culturing the exopolysaccharide; and an exopolysaccharide having a structural formula as shown in formula (I) being produced by the strain, as well as a production method thereof and its use in promoting the propagation of bifidobacterium. The exopolysaccharide shown by formula (I) has a moderate degree of polymerization (DP=15-30) and has the functions of promoting the propagation of bifidobacterium, as well as adjusting human intestinal microflora.
Type:
Grant
Filed:
September 21, 2018
Date of Patent:
August 11, 2020
Assignee:
BRIGHT DAIRY & FOOD CO., LTD.
Inventors:
Zhengjun Wu, Benheng Guo, Caixia Gao, Zhenmin Liu, Feng Hang, Jin Han
Abstract: Method for lyophilisation of a simple of fecal microbiota. The present invention relates to a method for lyophilisation of a sample of fecal microbiota from a donor subject, comprising the following steps: A) mixing of a sample of fecal microbiota from a donor subject with a diluent selected from polyols, disaccharides to pentasaccharides, maltodextrins and mixtures thereof, and B) freezing the mixture obtained in A) at a temperature of less than ?50° C., preferably of between ?70° C. and ?100° C., followed by the lyophilisation thereof.
Type:
Grant
Filed:
December 19, 2016
Date of Patent:
August 11, 2020
Assignees:
MAAT PHARMA, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
Abstract: The presently disclosed subject matter provides compositions, methods, and kits comprising shape memory particles that can be used for delivering a drug and/or treating a disease or disorder in a patient. Specifically, shape changes in the presently disclosed shape memory particles can be used to control drug delivery spatially and/or temporally in a patient. Also provided are compositions, methods, and kits comprising nanoparticles and hypoxia-inducible factor (HIF) inhibitors with or without chemotherapeutic agents for inhibiting HIF activity in a patient and/or treating a hypoxia-associated disease or disorder.
Type:
Grant
Filed:
April 6, 2016
Date of Patent:
June 30, 2020
Assignee:
The Johns Hopkins University
Inventors:
Qiongyu Guo, Jordan J. Green, Randall A. Meyer, Corey J. Bishop, Anand Kumar, Gregg L. Semenza
Abstract: The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of a ClpB protein or an effective amount of a bacterium that expresses the ClpB protein.
Type:
Grant
Filed:
April 5, 2016
Date of Patent:
June 16, 2020
Assignees:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE HOSPITALIER UNIVERSITAIRE DE ROUEN, UNIVERSITÉ´DE ROUEN, TARGEDYS
Inventors:
Sergueï Fetissov, Pierre Dechelotte, Jonathan Breton, Gregory Lambert, Romain Legrand
Abstract: The present disclosure provides methods, systems, compositions, and kits to address the need for microbiome-related treatment of health conditions and disease. The present disclosure provides for treatment of metabolic conditions using microbial compositions.
Type:
Grant
Filed:
October 12, 2018
Date of Patent:
June 9, 2020
Assignee:
Pendulum Therapeutics, Inc.
Inventors:
Colleen Cutcliffe, John S. Eid, James H. Bullard, Marcus F. Schicklberger
Abstract: Provided is a composition containing Bifidobacterium for alleviating, preventing or treating rheumatoid arthritis. The Bifidobacterium bifidum ATT newly isolated according to the present invention is useful as a rheumatoid arthritis medicine or a probiotic material for alleviating rheumatoid arthritis owing to potent efficacy in treating rheumatoid arthritis.
Type:
Grant
Filed:
May 11, 2018
Date of Patent:
April 14, 2020
Assignees:
BIFIDO CO., LTD., THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors:
Geun Eog Ji, Yunju Jeong, Hui Fang, Bin Kwon, Sung-Hwan Park, Mi-La Cho, Ji-Hyeon Ju, Seung-Ki Kwok, Jennifer Lee, Ji-Won Kim, Seon-Yeong Lee, Jun-Geol Ryu, Joo-Yeon Jhun, Jae-yoon Ryu, Hyeon-Beom Seo
Abstract: The present invention comprises methods and compositions for the reduction of oxalate in humans, and methods for the purification and isolation of recombinant oxalate reducing enzyme proteins. The invention provides methods and compositions for the delivery of oxalate-reducing enzymes in particle compositions. The compositions of the present invention are suitable in methods of treatment or prevention of oxalate-related conditions.
Type:
Grant
Filed:
November 10, 2017
Date of Patent:
February 25, 2020
Assignee:
OXTHERA INTELLECTUAL PROPERTY AB
Inventors:
Harmeet Sidhu, Aaron Blake Cowley, Carl-Gustaf Golander, Qingshan Li
Abstract: This document provides methods and materials related to Prevotella histicola preparations. For example, Prevotella histicola preparations in the form of an oral medicament or dietary supplement (e.g., a pill, tablet, capsule) are provided. In addition, methods and materials for using a Prevotella histicola preparation provided herein as an anti-inflammatory agent are provided.
Type:
Grant
Filed:
September 26, 2017
Date of Patent:
February 11, 2020
Assignee:
Mayo Foundation for Medical Education and Research
Inventors:
Joseph A. Murray, Eric V. Marietta, Susan H. Barton, Veena Taneja, Ashutosh Mangalam
Abstract: The invention relates to the fields of application of health, biotechnology and nutrition, the aim of the invention being to provide a gelatinous mixture of probiotics and prebiotics with synergic symbiotic action for the treatment of chronic renal disease, the characteristics and components thereof reducing the concentration of uremic toxins, improving the renal function of the patient with an increase in urea, creatinine, uric acid, p-cresols or indoles in the blood. The gelatinous mixture of probiotics and prebiotics with synergic symbiotic action for the treatment of chronic renal disease is easier to administrate orally as it does not require the consumption of liquids for the administration thereof, reducing liquid retention. Another advantage of the present invention is the fact that it refers to live and active bacteria. The present invention is also used a primary source of food with known prebiotic effects, an element which is not considered in other inventions; it is not in a pharmaceutical form.
Type:
Grant
Filed:
April 2, 2013
Date of Patent:
December 31, 2019
Assignee:
NUTRIMENTOS INTELIGENTES, S.A. DE C.V.
Inventors:
Fabiola Martín Del Campo López, Luis Gerardo Gonzalez Delgado, Daniela Viramontes Horner, Guillermo García García, Julio Alberto Ramos De La Mora
Abstract: Compositions and methods for immunization against human breast cancer are disclosed. A breast cancer vaccine comprises an immunogenic polypeptide comprising human ?-lactalbumin.
Type:
Grant
Filed:
September 11, 2015
Date of Patent:
November 5, 2019
Assignee:
The Cleveland Clinic Foundation
Inventors:
Vincent K. Tuohy, Justin M. Johnson, Ritika Jaini
Abstract: Inoculation of ATM-deficient mice with probiotic microorganisms, such as L. johnsonii, changed immune parameters, decreased a marker of DNA damage and increased the lifespan of the mice. Compositions and methods described herein are useful for the treatment and prevention of Ataxia telangiectasia and other cancer-prone disease, such as p53 deficiency-associated cancers. Compositions and methods of the present invention are also useful for treating and preventing radiation-induced toxicity to normal tissue in a subject being exposed to radiation. Compositions and methods of the invention can increase lifespans in a simple, non-invasive manner.
Type:
Grant
Filed:
April 27, 2017
Date of Patent:
September 17, 2019
Assignee:
The Regents of the University of California
Inventors:
Mitsuko L. Yamamoto, Robert H. Schiestl, Ramune Reliene, James Borneman, Laura L. Presley, Jonathan Braun
Abstract: Provided are bioactive compounds and metabolites derived from Chromobacterium species culture responsible for controlling pests, compositions containing these compounds, methods for obtaining these compounds and methods of using these compounds and compositions for controlling pests.
Abstract: The present invention relates to methods of scalably producing microorganisms by propagating them within plant tissues and introducing them into agricultural seeds to improve their shelf-life during long-term storage, to produce substances of interest, and to create libraries of microbes.
Type:
Grant
Filed:
December 24, 2014
Date of Patent:
July 30, 2019
Assignees:
AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH, INDIGO AG, INC.
Inventors:
Birgit Mitter, Muhammad Naveed, Teresa Berninger, Stephane Compant, Angela Sessitsch, Geoffrey Von Maltzahn, Richard Bailey Flavell, Gerardo V. Toledo, Slavica Djonovic, Luis Miguel Marquez, David Morris Johnston, Yves Alain Millet, Jeffrey Lyford, Jonathan W. Leff, Phillip Samayoa, Craig Sadowski
Abstract: The present invention relates to a composition comprising at least one fucosylated oligosaccharide, for use in preventing and/or treating URT infections in an infant or young child fulfilling at least one of the following criteria: i) the infant or young child is born from a non-secretor mother and/or is fed with a mother's milk deficient in at least one fucosylated oligosaccharide(s) ii) the infant or young child has at least one sibling iii) the infant or young child was born by C-section.
Type:
Grant
Filed:
November 14, 2014
Date of Patent:
July 23, 2019
Assignee:
Nestec S.A.
Inventors:
Norbert Sprenger, Clemens Kunz, Dominique Brassart
Abstract: Disclosed herein is a composition containing turmeric starch for use as a prebiotic plant fiber. Also disclosed is a method to increase the viable counts of Bacillus coagulans MTCC 5856 by co-culturing with turmeric starch and the production of short chain fatty acids (SCFA) by Bacillus coagulans MTCC 5856 using turmeric starch.
Type:
Grant
Filed:
July 27, 2017
Date of Patent:
June 18, 2019
Assignee:
SAMI LABS LIMITED
Inventors:
Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali
Abstract: The invention relates to the cloning, sequencing and characterization of the gene responsible for Quorum Quenching (QQ) activity against Quorum Sensing (QS) signals of the Tenacibaculum sp. strain 20J (CECT7426). Said gene encodes a peptide having at least lactonase activity with a percentage of identity less than 38% with the lactonases described up until now for other species, as well as the sequences of the homologous genes present in other species of the genus Tenacibaculum. Said peptide shows a broad spectrum of activity degrading optionally substituted N-acyl-homoserine lactones (AHLs) of 4-14 carbon atoms in the side chain thereof, is active at pH comprised between 3 and 9, proteinase K- and chymotrypsin-resistant and does not interact with ?-lactam antibiotics.
Type:
Grant
Filed:
July 10, 2014
Date of Patent:
June 11, 2019
Assignees:
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, FUNDACIÓN PEDRO BARRIÉ DE LA MAZA, CONDE DE FENOSA
Inventors:
Ana María Otero Casal, Manuel Romero Bernárdez, Celia Mayer Mayer
Abstract: Provided herein are kits, compositions, and methods for diagnosing and treating interstitial cystitis (IC) and/or interstitial cystitis/bladder pain syndrome (IC/BPS) based on finding lower levels of certain bacteria in a subject's stool sample (e.g., O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis). In certain embodiments, then present invention provides probiotic formulations containing live bacteria (e.g., from O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis).
Type:
Grant
Filed:
October 10, 2017
Date of Patent:
June 11, 2019
Assignees:
Northwestern University, The Board of Trustees of the University of Illinoi
Inventors:
David J. Klumpp, Anthony J. Schaeffer, Bryan A. White
Abstract: The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.
Type:
Grant
Filed:
January 6, 2017
Date of Patent:
May 21, 2019
Assignee:
Ascus Biosciences, Inc.
Inventors:
Mallory Embree, Luke Picking, Grant Gogul, Janna Tarasova
Abstract: Disclosed herein is (i) a method related to the growth promotional activity of plant based fibers on Bacillus coagulans MTCC 5856; (ii) the combination of plant based fibers and Bacillus coagulans MTCC 5856 to inhibit Gram Negative pathogenic bacteria; and (iii) the production of short chain fatty acids (SCFA) by Bacillus coagulans MTCC 5856 using plant based fibers.
Type:
Grant
Filed:
June 14, 2017
Date of Patent:
May 21, 2019
Assignee:
SAMI LABS LIMITED
Inventors:
Muhammed Majeed, Kalyanam Nagabhushanam, Sivakumar Arumugam, Furqan Ali
Abstract: Selection of probiotic strains belonging to the genus Bifidobacterium and to a symbiotic composition containing the same for use of feeding infants, is described.
Type:
Grant
Filed:
May 9, 2012
Date of Patent:
May 14, 2019
Assignee:
PROBIOTICAL S.P.A.
Inventors:
Giovanni Mogna, Gian Paolo Strozzi, Luca Mogna
Abstract: A formulation for vaginal administration comprising an effective amount of a composition of dried Lactobacillus cells and boric acid, with a carrier. The composition can include one or more antioxidants. Optionally, the composition is in a unit dosage form. Also provided are methods for making and using the composition.
Abstract: A cannabinoid composition having an excipient including ?-tocopherol and at least one isolated cannabinoid having a purity of greater than 80%. The ?-tocopherol inhibits oxidation, regulates viscosity of the composition, and improves bioavailability of the cannabinoid. The composition includes a carrier oil mixed with the excipient and cannabinoid. In one embodiment, the at least one cannabinoid is an isolated cannabinoid having a greater than 80% purity, and preferably greater than 90% purity. The at least one cannabinoid is selected from the group consisting of phytocannabinoids, endocannabinoids, synthetic cannabinoids, and combinations thereof. The cannabinoid may be derived from plants other than cannabis sativa, or synthesized from fungi, bacteria, yeast or other synthetic method. Preferably the ?-tocopherol comprises at least 10% w/w of the composition.
Abstract: An IBTL system having a low GHG footprint for converting biomass to liquid fuels in which a biomass feed is converted to liquids by direct liquefaction and the liquids are upgraded to produce premium fuels. Biomass residues from the direct liquefaction, and optionally additional biomass is pyrolyzed using microwave pyrolysis to produce structured biochar, hydrogen for the liquefaction and upgrading, and CO2 for conversion to algae, including blue green algae (cyanobacteria) in a photobioreactor (PBR). Produced algae and diazotrophic microorganisms are used to produce a biofertilizer that also contains structured biochar. The structured biochar acts as a nucleation agent for the algae in the PBR, as a absorption agent to absorb inorganics from the biomass feed to direct liquefaction or from the liquids produced thereby, and as a water retention agent in the biofertilizer.
Type:
Grant
Filed:
December 15, 2019
Date of Patent:
November 17, 2020
Assignees:
ACCELERGY CORPORATION, SHANGHAI ADVANCED RESEARCH INSTITUTE OF THE CHINESE ACADEMY OF SCIENCE
Inventors:
Rocco A Fiato, Yuhan Sun, Mark Allen, Quanyu Zhao