Polysaccharide Of More Than Five Saccharide Radicals Attached To Each Other By Glycosidic Bonds Patents (Class 435/101)
  • Patent number: 11678669
    Abstract: Process for conferring a protection against a pathogen upon a plant by elicitation by an aqueous composition, the active agents of which are extracted from edible fungi (parasol mushroom, pleurotus, button mushroom). An alkaline extraction is carried out, then an enzymatic hydrolysis, to obtain a fraction less than 100 kDa. The process consists in spraying the aerial parts of the plant with the composition obtained in this way; this thereby acts to combat cryptogamic diseases of plants such as vines, fruit trees, vegetable crops and cereals.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: June 20, 2023
    Inventors: Céline Faugeron, Vincent Gloaguen, Cédric Astier, Charlotte Moine
  • Patent number: 11648336
    Abstract: The present invention relates to preparation of bioink composed of cellulose nanofibril hydrogel with native or synthetic Calcium containing particles. The concentration of the calcium containing particles can be between 1% and 40% w/v. Such bioink can be 3D Bioprinted with or without human or animal cells. Coaxial needle can be used where cellulose nanofibril hydrogel filled with Calcium particles can be used as shell and another hydrogel based bioink mixed with cells can be used as core or opposite. Such 3D Bioprinted constructs exhibit high porosity due to shear thinning properties of cellulose nanofibrils which provides excellent printing fidelity. They also have excellent mechanical properties and are easily handled as large constructs for patient-specific bone cavities which need to be repaired. The porosity promotes vascularization which is crucial for oxygen and nutrient supply. The porosity also makes it possible for further recruitment of cells which accelerate bone healing process.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: May 16, 2023
    Assignee: Cellink Bioprinting AB
    Inventors: Paul Gatenholm, Hector Martinez, Michela Schettino, Erik Gatenholm
  • Patent number: 11649472
    Abstract: The disclosure provides methods using mixed substrate cofeeding for bioproduct synthesis, which enables faster, more efficient, and higher yield carbon conversion in various organisms.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: May 16, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Junyoung Park, Nian Liu, Gregory Stephanopoulos
  • Patent number: 11525151
    Abstract: Described are methods for saccharifying starch-containing materials using a glucoamylase, methods for producing fermentation products, and fermentation products produced by the method thereof as well as methods for increasing starch digestibility in a ruminant using at least one of the glucoamylases described herein.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: December 13, 2022
    Assignee: DANISCO US INC.
    Inventors: Jing Ge, Xiaogang Gu, Helong Hao, Karsten Matthias Kragh, Jinahua (Jalsen) Li, Wenting Li, Zhongmei Tang, Shukun Yu, Bo Zhong, Kun Zhong, Zhengzheng Zou
  • Patent number: 11473051
    Abstract: A method of cultivating algal cells of an algae belonging to a class selected from Chlorophyceae, Euglenophyceae, Bacillariophyceae and Haptophyceae includes: irradiating the algal cells with an artificial light having a ratio of (i) photon flux density in a wavelength range of 520-630 nm to (ii) photosynthetic photon flux density, that is 65% or more; and measuring a condition of the algal cells and/or a condition of an algal cell culture provided by cultivating the algal cells. Irradiation and non-irradiation of the algal cells with the artificial light are switched, or the photon flux density in the wavelength range of 520-630 nm is changed, according to the measured condition of the algal cells and/or the measured condition of the algal cell culture.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: October 18, 2022
    Inventors: Tomohisa Hasunuma, Yuichi Kato, Yasuo Fujikawa, Tomohiro Tsurumoto
  • Patent number: 11363813
    Abstract: Hydrogels are blended with water to produce a hydrogel solution. Viscosity of the hydrogel solution is controlled by adjusting the ratio of hydrogel to water and/or by adjusting the blending conditions. The hydrogel solutions may be used to modify the rheology of agricultural compositions. The hydrogel may include lactose, which may be provided by a milk permeate waste stream from the dairy or food processing industry.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: June 21, 2022
    Assignee: WinField Solutions, LLC
    Inventors: Danny Brown, Christine Colby, Lillian Magidow, Megan Barta
  • Patent number: 11332728
    Abstract: The present disclosure relates to recombinant yeast strains capable of maintaining their robustness at high temperature as well as recombinant proteins expressed therefrom. The present disclosure also provides methods for using the recombinant yeast strain for making a fermentation product. The present disclosure further process a process for making recombinant yeast strains capable of maintaining their robustness at high temperature.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: May 17, 2022
    Assignee: Lallemand Hungary Liquidity Management LLC
    Inventors: Charles F. Rice, Ryan Skinner, Trisha Barrett, Aaron Argyros
  • Patent number: 11208644
    Abstract: Provided herein are recombinant glycoproteins (e.g., recombinant human ?-galactosidase-A proteins) with an altered (e.g., improved) glycosylation profile, and pharmaceutical compositions and kits including one or more of these proteins. Also provided are methods of generating a mammalian cell useful for recombinant expression of a glycoprotein (e.g., recombinant human ?-galactosidase-A), methods of producing recombinant glycoproteins, and methods of treatment that include administering to a subject at least one of the recombinant glycoproteins (e.g., recombinant human ?-galactosidase-A protein).
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: December 28, 2021
    Inventors: Karen Lee, Christopher Hwang, Christine DeMaria
  • Patent number: 11202761
    Abstract: The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: December 21, 2021
    Assignee: DA VOLTERRA
    Inventors: Francois Lescure, Jean De Gunzburg
  • Patent number: 11155847
    Abstract: The present invention provides a method for the production of oligosaccharides by the fermentation of dextran-sucrase-producing microorganisms with sucrose and maltose. The disclosed process allows for the control of the final composition of the isomaltooligosaccharides by adjustments to pH and the initial ratio of sucrose to maltose.
    Type: Grant
    Filed: August 22, 2015
    Date of Patent: October 26, 2021
    Assignee: ISOThrive Inc.
    Inventors: Lee Madsen, II, Jack Oswald, Donal F Day, Young Hwan Moon
  • Patent number: 11142781
    Abstract: The disclosure herein relates to a method for producing high-quality maltodextrin, and belongs to the technical field of maltodextrin. On the basis of a traditional enzymatic production process of maltodextrin, starch branching enzyme derived from Rhodothermus obamensis is introduced, an ?-1,4-glycosidic bond is cleaved, the cleaved short chain is ligated to a receptor chain to form an ?-1,6-branch point, so the degree of branching is increased and the maltodextrin has more cluster structures. Thereby, the aims that the stability of the maltodextrin is enhanced and the maltodextrin is not easy to retrograde are achieved, and the freeze-thaw stability of the maltodextrin is also improved. The method specifically comprises the steps of slurry preparation, spray liquefaction, starch branching enzyme action, filtration, decolorization, ion exchange, concentration, spray drying, and the like.
    Type: Grant
    Filed: January 20, 2020
    Date of Patent: October 12, 2021
    Assignee: Jiangnan University
    Inventors: Zhaofeng Li, Zhengbiao Gu, Zhe Wang, Caiming Li, Sijia Xu, Li Cheng, Yan Hong
  • Patent number: 11136569
    Abstract: Provided are a novel isoamylase improved in optimum temperature, and more specifically, improved in heat resistance, and a process for producing the isoamylase. An isoamylase having at least one amino acid mutation selected from the group consisting of D268A, M277I, A549P, A554P and A580T in an isoamylase consisting of an amino acid sequence represented by SEQ ID No: 1 or an isoamylase consisting of the amino acid sequence represented by SEQ ID No: 1 and having deletion, substitution or insertion of one to several amino acid residues.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: October 5, 2021
    Assignee: GODO SHUSEI CO., LTD.
    Inventors: Masahiro Baba, Ryoko Sano, Shun Ogawa, Hirofumi Horiguchi, Jun Yoshikawa
  • Patent number: 11129403
    Abstract: The present invention relates to fermentable soluble fibers, such as soluble corn fiber (SCF), and its uses in increasing colonic bacteria populations, and edible compositions useful in increasing colonic bacteria populations.
    Type: Grant
    Filed: March 22, 2014
    Date of Patent: September 28, 2021
    Assignee: Tate & Lyle Ingredients Americas LLC
    Inventors: Connie Marie Weaver, Cindy H. Nakatsu, Patricia Williamson, Andrew Joseph Hoffman, Lisa Marie Sanders
  • Patent number: 11124808
    Abstract: The present invention relates to a method for solubilisation or hydrolysis of Municipal Solid Waste (MSW) with an enzyme blend and an enzyme composition for solubilization of Municipal Solid Waste (MSW), the enzyme composition comprising a cellulolytic background composition and a protease, lipase and/or beta-glucanase.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: September 21, 2021
    Assignee: RENESCIENCE A/S
    Inventors: Hanne Risbjerg Soerensen, Lisa Rosgaard, Henrik B. Nielsen, Lone Baekgaard, Joanna Wawrzynczyk
  • Patent number: 11111498
    Abstract: The invention provides cereal plants having a high level of fructan useful for the production of a range of food, beverage, nutraceutical and pharmaceutical products. The invention provides methods of producing high-fructan products from plants modified to comprise a reduced level of an endogenous polypeptide with starch synthase activity, and products so produced. In some embodiments, plants are modified by introduction of an agent such as a nucleic acid molecule which down regulates endogenous starch synthase II gene expression.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: September 7, 2021
    Inventors: Colin Leslie Dow Jenkins, Bryan Charles Clarke, Zhongyi Li, Matthew Kennedy Morell
  • Patent number: 11110136
    Abstract: A composition comprising lactic bacteria for use in the preventive and/or curative treatment of bacterial infections, which cause urinary tract and/or bladder inflammations is described. The composition is in particular for the treatment of recurrent cystitis.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: September 7, 2021
    Assignee: PROBIOTICAL S.P.A.
    Inventor: Giovanni Mogna
  • Patent number: 11021684
    Abstract: A space-bred seawater Spirulina H11 strain. The strain exhibits high growth rate, capacity of simultaneously accumulating high contents of phycocyanin, Spirulina polysaccharides and ?-carotene, and excellent adaptability to outdoor environment, thus can be used to produce high-quality Spirulina powders, phycocyanin, Spirulina polysaccharides, and ?-carotene-rich Spirulina oil.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: June 1, 2021
    Inventors: Wenzhou Xiang, Li Tan, Tao Li, Hualian Wu, Jiayi Wu, Zishuo Chen, Dehai Liu, Dengliang Yang, Shengjie Lin, Weijie Zhang, Chubiao Zhang, Hao Chen
  • Patent number: 11000557
    Abstract: A composition comprising lactic bacteria for use in the preventive and/or curative treatment of bacterial infections, which cause urinary tract and/or bladder inflammations is described. The composition is in particular for the treatment of recurrent cystitis.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: May 11, 2021
    Assignee: PROBIOTICAL S.P.A.
    Inventor: Giovanni Mogna
  • Patent number: 10988727
    Abstract: The present disclosure pertains to novel cell cultivation and cell and/or cell-derived product production processes that have advantages over currently existing fermentation strategies. The processes and methods according to the present disclosure may be used for an efficient supply of highly viable and metabolically active eukaryotic cells for transient production platforms, as an alternative production process with advantages over currently applied processes (batch, fed-batch or perfusion strategies) and for generating metabolically highly active biomass for subsequent use for transient expression systems or infection by a virus or pseudovirus or in cell-free systems.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: April 27, 2021
    Inventors: Daniel Blessing, Tanja Holland, Markus Sack, Matthias Buntru, Simon Vogel
  • Patent number: 10973245
    Abstract: This invention relates to a composition for additives which can be employed in animal feeds, or as growth promoters, or as nutraceuticals, or as prebiotics, or as additives for the control and prophylaxis of pathogenic bacteria in the intestinal tract of animals or farmed animals. An immunomodulatory and promoter composition for controlling the population of undesirable bacteria of the intestinal microbiota, comprising the components indicated below: (a) Fructooligosaccharides (FOS); (b) Galacto-oligosaccharides (GOS); (c) Mannan-oligosaccharides (MOS); (d) 1,3 and 1,6 Beta-glucans.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: April 13, 2021
    Inventor: Victor Abou Nehmi Filho
  • Patent number: 10883126
    Abstract: This invention relates to a process for producing lactic acid or its salts that can be performed easily, reduce complicated steps, and provide high lactic acid yield and high productivity, wherein said process comprising of the following steps: (a) cultivating thermotolerance Bacillus genus bacteria to obtain a seed culture; (b) increasing cell number of bacteria by inoculating the seed culture contained from step (a) into a fermenter containing an initial carbon source under an aerobic condition; (c) fermenting the seed culture obtained from step (b) in the fermenter under a microaerobic condition to obtain lactic acid or its salts; wherein the step (b) comprising at least one addition of the carbon source under any one of the following conditions, where are independent to each other, to increase a concentration of the carbon source: when the concentration of the carbon source in the fermenter reduces to 50 % or less comparing to the initial concentration.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: January 5, 2021
    Inventors: Nuttha Thongchul, Vasana Tolieng, Phatthanon Prasitchoke
  • Patent number: 10851182
    Abstract: Provided herein are common starch-based and waxy starch-based hydrolyzed starches. The hydrolyzed starches described herein demonstrate desirable properties over existing hydrolyzed starches for food applications, including but not limited to, dairy, ready-to-eat cereal coatings, clean-label confectionary products, nutritional and cereal bars, crumb chocolate, infant and/or elderly nutrition.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: December 1, 2020
    Assignee: Cargill, Incorporated
    Inventors: Frank Derez, Baljit S. Ghotra, John R. Heigis, John Zupfer
  • Patent number: 10829567
    Abstract: Multi-phase biomaterials based on bacterially synthesized nanocellulose and method for producing same.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: November 10, 2020
    Assignee: JENACELL GMBH
    Inventors: Nadine Hessler, Barno Baumbach, Dieter Klemm
  • Patent number: 10808271
    Abstract: The present invention relates to the field of poly- and oligosaccharides and their dietary effects. In particular it relates to a method of producing an ?-glucan containing (?1?3) linked D-glucose units. The invention also provides a branched ?-glucan comprising alternating (?1?4) and (?1?3) glucosidic linkages and having (?1?3,4) branching points, a food composition, and the use of an ?-glucanotransferase enzyme for reducing the digestible carbohydrates of a starch containing food material. Further aspects of the invention are a bacteria, an enzyme and an expression vector.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: October 20, 2020
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Lubbert Dijkhuizen, Joana Gangoiti Munecas, Sander Sebastiaan Van Leeuwen, Christina Vafeiadi, Stephane Duboux
  • Patent number: 10793484
    Abstract: A strain of Gluconacetobacter diazotrophicus (Gd) characterised by the presence of at least one nucleic acid sequence selected from SEQ ID NOS 1-10 or variants or paralogues thereof and/or the presence of a single plasmid of about 17566 bp in size. Such strains, exemplified by IMI504853, are useful in agriculture, in particular as they are able to colonise plants intracellularly.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: October 6, 2020
    Assignee: Azotic Technologies LTD
    Inventors: David Dent, Dhaval Patel, Gary Devine
  • Patent number: 10760067
    Abstract: The present invention discloses a ?-galactosidase mutant, and a preparation method and application thereof, belonging to the fields of gene engineering and enzyme engineering. Amino acids of specific sites in the ?-galactosidase are mutated, the ?-galactosidase is transferred into a recombinant bacterium, and enzymatic transformation is performed under optimized conditions, so that the yield of galactooligosaccharide produced by the mutant reaches 59.8%, which is increased by about 70% as compared with that of wild enzyme, thereby implementing the increase of the galactooligosaccharide yield. The present invention has very high industrialized application value.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: September 1, 2020
    Assignee: Jiangnan University
    Inventors: Jing Wu, Dan Wu, Xin Gao
  • Patent number: 10703775
    Abstract: The present invention provides a method of enriching a lipopeptide in a microbial cell culture, the method comprising mixing an amphiphilic sulfonate and/or an amphiphilic sulfate with the cell culture to induce the formation of aggregates containing the lipopeptide, centrifuging the cell culture to generate a supernatant fraction and a pellet fraction, separating the pellet fraction from the supernatant fraction, and mixing the pellet fraction with a polyoxyethylene glycol alkyl ether to release the lipopeptide from the aggregates.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: July 7, 2020
    Assignee: Bayer CropScience LP
    Inventors: Chad Kimmelshue, Yan Li, Colleen S. Taylor, Hong Zhu
  • Patent number: 10683222
    Abstract: The present invention provides a process for the treatment of sewage sludge with enzymes, which process comprises treating a sewage sludge resulting from the treatment of municipal or industrial waste water with a composition comprising a fermentation supernatant product from a Saccharomyces cerevisiae culture and a non-ionic surfactant, wherein said fermentation supernatant product is free of active enzymes, at conditions suitable for generating said active enzymes from said sewage sludge in situ.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: June 16, 2020
    Assignee: Neozyme International, Inc.
    Inventors: Parker Dale, Parker David Dale
  • Patent number: 10662455
    Abstract: A process for producing alcohol from lignocellulosic biomass includes adding at least one of sulfur dioxide and sulfurous acid to the lignocellulosic biomass to provide an effective sulfur dioxide dosage and/or effective sulfur dioxide slurry concentration, each of which is calculated using the ratio of the volume of the slurry in the pretreatment reactor to the total volume of the pretreatment reactor, within a predetermined range.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: May 26, 2020
    Assignee: Iogen Corporation
    Inventors: Jeffrey S. Tolan, Daniel G. MacDonald, Kristin Martens, Natacha Leduc, Brian Foody
  • Patent number: 10626385
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity, catalytic domains, and cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains, and cellulose binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, or cellulose binding domains.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: April 21, 2020
    Inventors: Mary Ann Stringer, Brett McBrayer
  • Patent number: 10611804
    Abstract: A method for producing heparosan is provided. Heparosan is produced by culturing an Escherichia bacterium having a heparosan-producing ability and modified so that expression of one or more genes, such as rbsR, rbsK, rbsB, hsrA, glgB, glgX, micF, rcsD, rcsB, ybiX, ybil, ybiJ, ybiC, ybiB, rfaH, nusG, pcoR, pcoS, pcoE, yhcN, yhcO, aaeB, aaeA, aaeX, g1455, alpA, g1453, yrbA, mlaB, mlaC, mlaD, mlaE, mlaF, yrbG, norW, ybjI, ybjJ, ybjK, rybB, yjjY, yjtD, thrL, thrA, thrB, fruA, psuK, ytfT, yjfF, fbp, yagU, paoA, paoB, gsiC, gsiD, yliE, irp2, irp1, bhsA, ycfS, lepB, rnc, era, dapA, gcvR, bcp, hyfA, rpoE, nadB, yfiC, srmB, g1414, g1413, nuoE, nuoF, nuoG, glmZ, hemY, hemX, hemD, rlmL, artQ, artM, artJ, rlmC, ybjO, yejO, yejM, yejL, rpoS, ygbN, ygbM, ygbL, g3798, g3797, g3796, g3795, g3794, g3793, g3792, ryjA, soxR, soxS, yjcC, yjcB, efeU, and efeO, is/are increased in a medium, and collecting heparosan from the medium.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: April 7, 2020
    Assignee: AJINOMOTO CO., INC.
    Inventors: Shunsuke Yamazaki, Tomoko Shimizu, Kenichi Mori, Naoto Tonouchi
  • Patent number: 10582723
    Abstract: The present invention relates to yeast cell wall 5 compositions enriched with mannose, mannose extracts and processes for making the same.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: March 10, 2020
    Assignee: Biothera Pharmaceuticals, Inc.
    Inventors: Donald J. Cox, Michael Danielson, Kyle S. Michel
  • Patent number: 10415065
    Abstract: The disclosed subject matter relates generally to a method for modifying oil, and specifically to a process for increasing the concentration of polyunsaturated fatty acid in an oil composition.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: September 17, 2019
    Assignee: DSM IP Assets B.V.
    Inventors: Jaroslav A. Kralovec, Weijie Wang, James Colin Barrow
  • Patent number: 10415053
    Abstract: Method of increasing resistance to a pathogen or a pest in a plant comprising introducing into the plant and expressing therein a polynucleotide comprising a nucleotide sequence encoding a Qua-Quine Starch (QQS) polypeptide; method of producing a plant with increased resistance to a pathogen or a pest comprising crossing a plant obtained in accordance with the above method with a second plant to produce progeny plants and selecting progeny plants with increased resistance to a pathogen or a pest; a plant with increased resistance to a pathogen or a pest; a seed of the plant; a hybrid of the plant; and a seed of the hybrid plant.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: September 17, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ling Li, Eve Syrkin Wurtele
  • Patent number: 10383329
    Abstract: There is described a composition comprising a microparticle component; optionally an encapsulated active agent; and a preservative amount of one or more terpenes.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: August 20, 2019
    Assignee: Eden Research PLC
    Inventors: Alexander John Abrey, Kenneth William Brooks, Arthur Benjamin Norman Gill, Clive Roland Newitt
  • Patent number: 10351633
    Abstract: An enzymatically produced soluble ?-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble ?-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble ?-glucan fiber are also provided.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: July 16, 2019
    Inventors: Qiong Cheng, Robert Dicosimo, Arthur Ouwehand, Zheng You, Mark S. Payne, Jian Ping Lai, Kristin Ruebling-Jass, Steven Cary Rothman
  • Patent number: 10314852
    Abstract: The invention relates to a mixture of human milk oligosaccharides that consists essentially of: a) a component A which is 3-FL or DFL, a component B which is LNT, LNnT, LNFP-I or 2?-FL, a component C, which is LNFP-II when component B is LNT, or LNFP-III when component B is LNnT, or LNDFH-I when component B is LNFP-I, or DFL when component B is 2?-FL, and a component D, which is lactose when component A is 3-FL, or 2?-FL when component A is DFL, with the proviso that if component B is 2?-FL, then component A is 3-FL; or consists essentially of: b) 3-FL, a component E which is LNT, LNnT or LNFP-I, and a component F, which is LNFP-II when component E is LNT, or LNFP-III when component E is LNnT, or LNDFH-I when component E is LNFP-I, and to processes for producing them and their uses.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: June 11, 2019
    Assignee: GLYCOM A/S
    Inventors: Elise Champion, Bruce McConnell, Gyula Dekany
  • Patent number: 10301637
    Abstract: Materials and methods for making plants (e.g., Solanum varieties) with decreased levels of amylose are provided herein. The methods can include making mutations in the gene encoding granule bound starch synthase (GBSS), where the mutations are induced using a rare-cutting endonuclease.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: May 28, 2019
    Assignee: CELLECTIS
    Inventors: Benjamin Clasen, Daniel F. Voytas, Feng Zhang
  • Patent number: 10292927
    Abstract: Microfibrous cellulose (MFC) broths are provided having improved performance as compared to wet cake microfibrous cellulose (MFC) and powdered microfibrous cellulose (MFC). In embodiments, compositions having an effective amount of an MFC broth and an effective amount of a surfactant have an improved yield value as compared to a composition having a surfactant and a wet cake MFC, a powdered MFC, or a combination thereof at the same concentration as the MFC broth. Also, methods are provided for improving the yield value of surfactant compositions by adding an effective amount of a microfibrous cellulose broth to an effective amount of surfactant to provide a surfactant composition having a yield value that is higher than a composition having the surfactant and a wet cake MFC, a powdered MFC, or a combination thereof at the same concentration as the microfibrous cellulose broth.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: May 21, 2019
    Assignee: CP Kelco U.S., Inc.
    Inventors: John Swazey, Neil Morrison, Zhi-fa Yang, Jacqueline Compton, Tim Nolan
  • Patent number: 10286005
    Abstract: The present invention provides an antioxidant, an ROS inhibitor, an antioxidant enzyme production promoter, an antioxidant cosmetic, a UV care cosmetic, a prophylactic or therapeutic agent for gastrointestinal tract inflammation, and an antioxidant food or beverage, each containing an enzymatically synthesized glycogen (ESG) or an ?-amylase digest (RG) thereof, as well as use for enhancing an antioxidative effect in vivo.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: May 14, 2019
    Assignee: EZAKI GLICO CO., LTD.
    Inventors: Takashi Furuyashiki, Hitoshi Ashida, Takakazu Mitani, Yasukiyo Yoshioka
  • Patent number: 10265340
    Abstract: Immune function of an animal can be modulated by administration of a composition that includes beta glucan. The beta glucan can be derived from Euglena, which provides a form of beta glucan that is different from other organisms, where the beta glucan is predominantly unbranched beta-(1,3)-glucan. Beta glucan can also be complexed with a metal, such as zinc, and/or can combined with an animal feed component to form an animal feed composition. Use of such compositions can improve the well being of an animal, and may augment or even replace the use of antibiotics in certain circumstances.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: April 23, 2019
    Inventors: Jeffrey Richard LeBrun, Robert Levine, Geoffrey Paul Horst
  • Patent number: 10227853
    Abstract: The present invention provides methods for increasing the viscosity of the drive fluid for displacing oil from a subterranean formation by the use of microorganisms selected or modified for the ability to produce cell free polymers without the formation of any significant bioplugging biofilm or capsule.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: March 12, 2019
    Assignee: Geo Fossil Fuels, LLC
    Inventors: William J. Kohr, David J. Galgoczy, Zhaoduo Zhang
  • Patent number: 10212905
    Abstract: A novel maize variety designated PH41DJ and seed, plants and plant parts thereof are provided. Methods for producing a maize plant comprise crossing maize variety PH41DJ with another maize plant are provided. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH41DJ through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby are provided. Hybrid maize seed, plants or plant parts are produced by crossing the variety PH41DJ or a locus conversion of PH41DJ with another maize variety.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: February 26, 2019
    Inventors: Blaine Earl Johnson, Brandon Michael Wardyn
  • Patent number: 10184141
    Abstract: Recombinant microorganisms configured for increased glycogen production. The recombinant microorganisms comprise a recombinant nucleic acid configured to express or overexpress a glucose-1-phosphate adenylyltransferase. The recombinant microorganisms produce an increased amount of glycogen compared to a corresponding microorganism not comprising the recombinant nucleic acid.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: January 22, 2019
    Inventors: Brian F. Pfleger, Andrew L. Markley
  • Patent number: 10130666
    Abstract: The present invention provides Lactobacillus plantarum CJLP133 KCTC 11403BP, a composition for treating intestinal diseases comprising the lactic acid bacteria, and a composition for enhancing immunity comprising the lactic acid bacteria.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: November 20, 2018
    Inventors: Bong Joon Kim, Heon Woong Jung, Se Hee Hwang, Jin Hee Lee, Kang-Pyo Lee, Kwang Woo Hwang, Tae Joon Won
  • Patent number: 10117901
    Abstract: Provided are a prophylactic or therapeutic agent for a peptic ulcer, a food additive for prevention and treatment of a peptic ulcer, an iNOS expression inhibitor, and a COX-2 expression inhibitor, all of which have little side effects. The prophylactic or therapeutic agent contains a Euglena-derived material as an active ingredient. The Euglena-derived material may be Euglena, paramylon, or an acid-treated paramylon. The prophylactic or therapeutic agent is useful for the prevention or treatment of a peptic ulcer induced by psychological stress. The peptic ulcer may be a gastric ulcer. The food additive contains a Euglena-derived material as an active ingredient.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: November 6, 2018
    Assignee: euglena Co., Ltd.
    Inventors: Eriko Yoshida, Yuta Asayama, Osamu Iwata, Ayaka Nakashima, Kengo Suzuki, Misa Ohgushi, Naoki Harada, Yoshihisa Nakano
  • Patent number: 10100324
    Abstract: The specification provides methods of obtaining a genetically modified plant which has increased production potential compared to a control plant, the method comprising the steps of i) obtaining a plurality of plants at least one of which comprises in its genome a heterologous polynucleotide, ii) identifying from the plurality of plants a plant which has increased production potential relative to the control plant and comprises the heterologous polynucleotide, and iii) selecting the genetically modified plant, wherein the polynucleotide comprises a transcriptional control sequence operably linked to a nucleic acid sequence which encodes an agent that modifies endogenous starch phosphorylation and/or starch degradation in the plant. In some embodiments, the plant has increased endogenous glycosylase or increased digestibility compared to a control plant.
    Type: Grant
    Filed: November 27, 2008
    Date of Patent: October 16, 2018
    Inventors: Jean-Philippe Francois Michel Ral, Zhongyi Li, Matthew Kennedy Morell
  • Patent number: 10100298
    Abstract: The present invention relates to the field of genetic engineering and enzyme engineering, and more particularly relates to a maltooligosyl trehalose synthase mutant and its application. The present invention provides a series of maltooligosyl trehalose synthase mutants with improved enzyme activity.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: October 16, 2018
    Assignee: Jiangnan University
    Inventors: Jing Wu, Lingqia Su, Kailin Yao
  • Patent number: 10093995
    Abstract: Lactobacillus plantarum CJLP243 (KCTC 11045P), a composition for treating intestinal diseases comprising Lactobacillus plantarum CJLP243, and a composition for enhancing immune response comprising Lactobacillus plantarum CJLP243.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: October 9, 2018
    Inventors: Bong Joon Kim, Heon Woong Jung, Kang Pyo Lee, Sae Hun Kim, Tae Hoon Chun, Kwang Woo Hwang, Tae Joon Won
  • Patent number: 10059964
    Abstract: An object of the present invention is to provide a sucrose unassimilating yeast which has a flocculation ability and has much of a proven performance of food production. The present invention pertains to a yeast strain expressed by accession number: NITE BP-1587.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: August 28, 2018
    Inventors: Takayuki Masuda, Taku Kato