Bacillus (e.g., B. Subtilis, B. Thuringiensis, Etc.) Patents (Class 435/252.5)
  • Patent number: 8404474
    Abstract: The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacterium is modified so that activities of D-xylulose-5-phosphate phosphoketolase and/or fructose-6-phosphate phosphoketolase are enhanced. The present invention also provides a method for producing the useful metabolite using the bacterium.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: March 26, 2013
    Assignee: Ajinomoto Co., Inc.
    Inventors: Yury Ivanovich Kozlov, Akito Chinen, Hiroshi Izui, Yoshihiko Hara, Hisashi Yasueda, Konstantin Vyacheslavovich Rybak, Ekaterina Aleksandrovna Slivinskaya, Joanna Yosifovna Katashkina
  • Publication number: 20130071907
    Abstract: A bacillus composition characterized by fast germination and outgrowth in bile salts (simulated gut environment) and by high-level secretion of phytase. The bacillus composition may be used as supplement in animal feed where it has a probiotic (health promoting) effect and increases the digestion and availability of nutrients from animal feeds.
    Type: Application
    Filed: November 14, 2012
    Publication date: March 21, 2013
    Applicant: Chr. Hansen A/S
    Inventor: Chr. Hansen A/S
  • Publication number: 20130064927
    Abstract: The disclosure relates to enzyme producing Bacillus strains that provide benefits to animals and methods of using these strains. In one embodiment, the disclosure relates compositions comprising the enzyme producing Bacillus strains. In yet another embodiment, the disclosure relates to a feed for an animal comprising enzyme producing Bacillus strains.
    Type: Application
    Filed: August 24, 2012
    Publication date: March 14, 2013
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Mari Ellen Davis, Justin Sawall, Anthony Neumann, Greg Siragusa, Luis Romero
  • Publication number: 20130065293
    Abstract: The present invention has objects to provide a glucan useful as water-soluble dietary fiber, its preparation and uses. The present invention solves the above objects by providing a branched ?-glucan, which is constructed by glucose molecules and characterized by methylation analysis as follows: (1) Ratio of 2,3,6-trimethyl-1,4,5-triacetyl-glucitol to 2,3,4-trimethyl-1,5,6-triacetyl-glucitol is in the range of 1:0.6 to 1:4; (2) Total content of 2,3,6-trimethyl-1,4,5-triacetyl-glucitol and 2,3,4-trimethyl-1,5,6-triacetyl-glucitol is 60% or higher in the partially methylated glucitol acetates; (3) Content of 2,4,6-trimethyl-1,3,5-triacetyl-glucitol is 0.5% or higher but less than 10% in the partially methylated glucitol acetates; and (4) Content of 2,4-dimethyl-1,3,5,6-tetraacetyl-glucitol is 0.5% or higher in the partially methylated glucitol acetates; a novel ?-glucosyltransferase which forms the branched ?-glucan, processes for producing them, and their uses.
    Type: Application
    Filed: November 1, 2012
    Publication date: March 14, 2013
    Applicant: Hayashibara Co., Ltd.
    Inventor: Hayashibara Co., Ltd.
  • Patent number: 8383097
    Abstract: The present invention relates to bacteria cultures and composition comprising one or more cultures of the invention. The invention also relates to methods of washing or cleaning laundry or fabrics and surfaces as well as degrading waste material using a bacteria culture of the invention.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: February 26, 2013
    Assignee: Novozymes Biologicals, Inc
    Inventor: Michael Eric Frodyma
  • Publication number: 20130045185
    Abstract: The disclosure relates to strains, compositions and methods for detoxifying a mycotoxin. In another embodiment, the disclosure relates to strains, compositions and methods for alleviating the gastrointestinal inflammatory response resulting from ingestion of mycotoxins. In one embodiment, the strains are Bacillus strains. In another embodiment, the strains are lactic acid bacteria.
    Type: Application
    Filed: August 17, 2012
    Publication date: February 21, 2013
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Mari Ellen Davis, Joshua Rehberger, Kimberly Novak, Thomas G. Rehberger
  • Patent number: 8377455
    Abstract: New Bacillus licheniformis strain named V9T14 that produces a new biosurfactant composition that is effective against colonization and/or bio film formation from bacteria. The new biosurfactant composition can be used in combination with biocides for preventing formation and/or for eradicating bacteria grown planktonically and/or as a biofilm, preferably on biotic and/or abiotic surfaces.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: February 19, 2013
    Assignees: PAN-ECO S.A., University Technologies International LP
    Inventors: Howard Ceri, Raymond J Turner, Maria Giovanna Martinotti, Fabrizio Rivardo, Gianna Allegrone
  • Patent number: 8372601
    Abstract: The disclosure of the present application provides polypeptide sequences and nucleotide sequences coding for the polypeptide sequences of proteins used in the production of APPA-containing peptides. In at least one embodiment of the present disclosure, an isolated nucleic acid is disclosed which comprises a nucleotide sequence encoding a polypeptide having a sequence identity of 60 percent or greater to an amino acid sequence selected from the group consisting of SEQ ID NOS: 2-13, and 15-23.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: February 12, 2013
    Assignee: University of Illinois at Urbana-Champaign
    Inventors: William W. Metcalf, Wilfred A. van der Donk, Junkal Zhang, Benjamin T. Circello, Svetlana A. Borisova
  • Publication number: 20130031673
    Abstract: Compositions comprising microbiological strains and cultures and methods of use thereof are provided herein. Certain strains, cultures, and compositions thereof are useful for the control of head blight disease, for example, of various crop plants. Biological control compositions, and methods of use thereof to prevent, inhibit or treat the development of plant pathogens or disease and for preserving plant yield, are also provided.
    Type: Application
    Filed: July 24, 2012
    Publication date: January 31, 2013
    Inventors: Christopher J. Grandlic, Wayne A. Green, Janne S. Kenovuo, Ryan McCann
  • Patent number: 8361762
    Abstract: The invention features methods for producing isoprene from cultured cells using a feedback-resistant mevalonate kinase polypeptide, such as an archaeal mevalonate kinase polypeptide. The resulting isoprene compositions may have increased yields and/or purity of isoprene.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: January 29, 2013
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Zachary Q. Beck, Anthony R. Calabria, Michael C. Miller, Dmitrii V. Vaviline, Alex T. Nielsen
  • Patent number: 8349337
    Abstract: The invention describes therapeutic compositions including a lactic acid-producing bacteria, such as isolated Bacillus coagulans, in combination with a cholesterol-reducing agent for use in reducing LDL cholesterol and serum triglycerides. Also described are therapeutic methods using the compositions and systems containing the therapeutic compositions.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: January 8, 2013
    Assignee: Ganeden Biotech, Inc.
    Inventors: Sean Farmer, Andrew R. Lefkowitz
  • Publication number: 20120328572
    Abstract: Disclosed herein are microbiocidal compositions that include spore-forming strains of Bacillus. The compositions may be utilized to treat or prevent disease in aquatic animals such as farmed fish or crustaceans.
    Type: Application
    Filed: April 30, 2012
    Publication date: December 27, 2012
    Applicant: AUBURN UNIVERSITY
    Inventors: Jeffery Terhune, Mark Liles, Joseph Kloepper
  • Publication number: 20120331589
    Abstract: The subject invention includes methods and plants for controlling lepidopteran insects, said plants comprising Cry1Fa and Cry1Da core toxin containing proteins in combination to delay or prevent development of resistance by the insect(s).
    Type: Application
    Filed: December 16, 2010
    Publication date: December 27, 2012
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Thomas Meade, Kenneth Narva, Nicholas P. Storer, Joel J. Sheets, Aaron T. Woosley, Stephanie L. Burton
  • Publication number: 20120329138
    Abstract: A process for separation of a mixture containing a microbial substance and a liquid using deformable filter is provided.
    Type: Application
    Filed: December 19, 2011
    Publication date: December 27, 2012
    Applicant: SHELL OIL COMPANY
    Inventors: Henry Van Kaathoven, Johannes Pieter Haan, Wilhelmus Maria Bond, Johannes Leendert Willem Cornelis Den Boestert
  • Patent number: 8338160
    Abstract: A novel bacterial strain of Bacillus thuringiensis for inhibiting insect pests is provided, wherein the Bacillus thuringiensis includes the fragments of cry1Aa, a cry1Ab, a cry1C, a cry1D and a cry1F genes.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: December 25, 2012
    Assignee: Taiwan Agricultural Chemicals and Toxic Substances Research Inst., Council of Agriculture
    Inventors: Ching-Chou Tzeng, Suey-Sheng Kao
  • Patent number: 8329446
    Abstract: The present invention provides a biocontrol agent for the prevention and/or reduction of mold during mushroom production. In particular, the invention utilizes Bacillus spp. as an agent for the control of mold caused by Trichoderma spp. The Bacillus spp. is a biologically pure culture of Bacillus subtilis strain J-P13.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: December 11, 2012
    Assignee: Monaghan Mushrooms Ltd.
    Inventors: Nader Gheshlaghi, Jack Verdellen
  • Publication number: 20120295335
    Abstract: A method to prevent contamination of feed line(s) and nutrient feed reservoirs(s) is disclosed. In this method the growth medium which flows from the nutrient feed reservoir through the feed line to the bioreactor contains at least one nutritional component supplied at a concentration which is inhibitory to cell growth. The inhibitory nutritional component in the growth medium prevents back growth of cells from the bioreactor into the feed line(s). The growth medium with inhibitory nutritional component is diluted in the bioreactor.
    Type: Application
    Filed: November 16, 2011
    Publication date: November 22, 2012
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventor: Scott Christopher Jackson
  • Publication number: 20120295334
    Abstract: An improved fermentation device and method uses a combination of substantially pure Oxygen as the Oxygenation gas and a separate air (or other Oxygen reducing gas) purge through the headspace of a fermentation device. The air injection and air purge vent line are configured to maintain a backpressure within the headspace. The air purge permits improved oxygen utilization and increases safety through dilution and removal of ammonia gas emitted during fermentation.
    Type: Application
    Filed: May 19, 2011
    Publication date: November 22, 2012
    Applicant: AIR LIQUIDE INDUSTRIAL U.S. LP
    Inventor: Sudhir R. Brahmbhatt
  • Patent number: 8304225
    Abstract: A novel bacterial strain of Bacillus thuringiensis for inhibiting insect pests is provided, wherein the Bacillus thuringiensis includes the gene fragments of cry1Ab, cry1Ac, cry1D, and cry1E.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: November 6, 2012
    Assignee: Taiwan Agricultural Chemicals and Toxic Substances Research Institute, Council of Agriculture
    Inventors: Ching-Chou Tzeng, Sheueh Kuo, Suey-Sheng Kao
  • Patent number: 8273346
    Abstract: The invention relates generally to digestive disorders, and in particular to methods for treating irritable bowel syndrome by increasing carbohydrate absorption by administering a composition containing a Bacillus coagulans bacterium.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: September 25, 2012
    Assignee: Ganeden Biotech, Inc.
    Inventors: Sean Farmer, Andrew Lefkowitz
  • Patent number: 8268608
    Abstract: The present invention provides a method of treating biomass that reduces water-polluting substances, suppresses the production of malodorous gases and greenhouse gases, decreases the nitrogen content in the compost or livestock bedding thus prepared, and furthermore, easily treats nitrogen-containing biomass in a short time at high temperature. The present invention also provides compost and livestock bedding produced by the method and a biomass treating agent. The method of treating biomass includes blending, with nitrogen-containing biomass, a Geobacillus microorganism having denitrification capability and a fermentation promoter that promotes the fermentation of the nitrogen-containing biomass by the Geobacillus microorganism.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: September 18, 2012
    Assignees: Menicon Co., Ltd., Toyota Jidosha Kabushiki Kaisha
    Inventors: Yutaka Matano, Ikuko Sugiyama, Shiori Emoto, Chikako Nakamura, Ikuo Fukumura, Masashi Takahashi
  • Publication number: 20120230965
    Abstract: The present invention relates to a novel microorganism producing L-type poly-gamma-glutamic acid and an L-type poly-gamma-glutamic acid produced thereby and, more particularly, to Bacillus megaterium Toha (KCTC11752BP) isolated from salt-fermented Toha shrimps (Korean traditional fermented food) and an L-type poly-gamma-glutamic acid produced thereby. The novel microorganism Bacillus megaterium Toha (KCTC11752BP) has the ability to produce L-type poly-gamma-glutamic acid which can be used in high-value-added microbial agents, probiotic agents, immune-activating agents, animal drugs, cosmetics, moisture absorbers, thickeners, biodegradable plastics, etc.
    Type: Application
    Filed: December 7, 2011
    Publication date: September 13, 2012
    Applicants: BIOLEADERS CORPORATION, THE INDUSTRY AND ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY, KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, KOOKMIN UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Moon-Hee SUNG, Chul Joong KIM, Haryoung POO, Mi-Sun KWAK, Sung-Bin PARK, Dong-Hwan CHOI, Ji Yeon KIM
  • Publication number: 20120231951
    Abstract: The present invention relates to novel strains of Bacillus and methods of their use for enhancing the growth, promoting plant health or controlling diseases or pests of a plant.
    Type: Application
    Filed: December 19, 2011
    Publication date: September 13, 2012
    Inventors: Magalie GUILHABERT-GOYA, Sarah F. HOVINGA, Daniel M. JOO, Jonathan S. MARGOLIS, Sarah J. MILLS, Varghese THOMAS, Damian CURTIS, Reed NATE ROYALTY, Roy WHITSON
  • Publication number: 20120214221
    Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first Bacillus cell relative to expression of the same genes in one or more second Bacillus cells using microarrays containing Bacillus genomic sequenced tags. The present invention also relates to computer readable media and computer-based systems. The present invention further relates to substrates containing an array of Bacillus licheniformis or Bacillus clausii GSTs.
    Type: Application
    Filed: April 30, 2012
    Publication date: August 23, 2012
    Applicants: Novozymes, Inc., Novozymes A/S
    Inventors: Randy M. Berka, Ib Groth Clausen, Alexandre Bolotine, Alexei Sorokine, Alla Lapidus
  • Patent number: 8246965
    Abstract: Bacillus isolates and compositions comprising the same are provided. Also provided are methods of inducing systemic acquired resistance to infection in a plant by applying a composition comprising a Bacillus control agent to said plant wherein said plant is capable of producing defense proteins.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: August 21, 2012
    Assignee: Montana State University
    Inventors: Barry Jacobsen, Nina K. Zidack, Rebecca Larson
  • Publication number: 20120208230
    Abstract: The present invention relates to an EM-lacquer water solution mixed with a natural component, a method for preparing a fermented anti-oxidant material using the same, and a method for processing the material. Particularly, the EM-lacquer water solution mixed with a natural component is prepared by mixing an EM-lacquer solution, which is a mixture of a crude solution of effective micro-organisms (EM) 20˜35 weight percent and a lacquer water solution 65˜80 weight percent, and at least one natural component selected from a group comprising of organic brown sugar, bay salt, mandarin orange oil, Japanese apricot concentrate, Opuntia humifusa powder, dried orange peel powder, green tea powder, sea tangle powder, rice bran, camellia oil and bean powder, on the basis of the EM-lacquer water solution 20 L. Therefore, it can be used for daily life, industry, environmental purification and the like because it is made of non-toxic materials.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Inventor: Jeong Wan Ha
  • Patent number: 8236549
    Abstract: The present disclosure relates to a strain of Bacillus amyloliquefaciens bacteria that hyperproduces amylase enzyme and protease enzyme. The strain is also suitable for producing lipase for the degradation of oleaginous materials such as fats, greases and cooking oils. The strain also has excellent fungicidal and/or fungistatic qualities. The strain of the present disclosure and the enzymes produced thereby have a number of applications, including agricultural uses, laundry and dish detergents, drain cleaners and spot removers, and among other things, baking applications.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: August 7, 2012
    Assignee: Novozymes Biologicals, Inc.
    Inventors: Yaowei Kang, Shawn Semones, Jessica Smith, Michael Frodyma
  • Patent number: 8227235
    Abstract: Disclosed herein are compositions for the treatment of a disease in an animal including yeast extract of Saccharomyces cerevisiae, Bacillus licheniformis or Bacillus subtilis spores, and a carrier. Also included are animal feed compositions including the composition for the prevention, control and/or treatment of a disease in an animal and an animal's food/feed. The compositions are useful to prevent, control, and treat diseases such as necrotic enteritis in poultry when used in combination with an anticoccidal ionophore or coccidiosis vaccine.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: July 24, 2012
    Assignee: Alpharma, LLC
    Inventors: James Skinner, Doug Rupp
  • Publication number: 20120178143
    Abstract: The present invention relates to the identification of novel hydrolases in gram positive microorganisms. The present invention provides amino acid sequences for the hydrolase. The present invention provides host cells which comprise nucleic acid encoding the hydrolase. The present invention also provides cleaning compositions, animal feeds and compositions used to treat a textile that include the hydrolase of the present invention.
    Type: Application
    Filed: January 16, 2012
    Publication date: July 12, 2012
    Applicant: DANISCO US INC.
    Inventor: David A. Estell
  • Patent number: 8206966
    Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: June 26, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascāo-Pereira, James T. Kellis, Jr., Bradley A. Paulson, Scott D. Power, Sandra W. Ramer, Vivek Sharma, Andrew Shaw, Jayarama K. Shetty, Donald E. Ward
  • Publication number: 20120156759
    Abstract: A method for the biological decomposition of organic compounds of the group of hydrocarbons, fats, oils, waxes, and derivatives thereof as well as mixtures thereof in media polluted therewith, in the presence of at least one dispersant, wherein the medium polluted with the pollutants is treated with at least one dispersant and with microorganisms.
    Type: Application
    Filed: June 15, 2010
    Publication date: June 21, 2012
    Applicants: TOTAL RAFFINAGE & MARKETING, GEORG FRITZMEIER GMBH & CO. KG
    Inventors: Ursula Fritzmeier, Robert Mallee, Achim Wiessler
  • Patent number: 8192977
    Abstract: This invention relates to ethanol production as a product of bacterial fermentation.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: June 5, 2012
    Assignee: Elsworth Biotechnology Limited
    Inventors: Edward Green, Muhammad Javed, Namdar Baghaei-Yazdi
  • Publication number: 20120128827
    Abstract: The present product (“invention”) corresponds to a new strain of Bacillus subtilis NRRLB-50213 which produces secondary metabolites, bioactive substances and biodegrading enzymes. This strain of bacteria and/or its derivatives has/have the capacity to form functional feeds with high starch and/or soy flour content, as well as inhibiting the growth of pathogenic microorganisms. Functional feeds formulated with the NRRLB-50213 strain and high concentrations of vegetable flours have the capacity to generate growth, weight gain and survival equal to or greater than those generated by feeds which contain high fish flour or other animal protein content. Included in this invention are methods and formulas which increase growth, weight gain and survival percentage, since the decomposition and assimilation of formulated functional nutrients based on vegetable flour and the NRRLB-50213 strain of Bacillus subtilis are improved and maximized.
    Type: Application
    Filed: November 18, 2011
    Publication date: May 24, 2012
    Applicant: CENTRO DE INNOVACION BIOTECHOLOGIVA, A.C.
    Inventor: JOSÉ LEONEL OCHOA
  • Publication number: 20120124898
    Abstract: This invention provides co-cultures of photosynthetic microorganisms and biofuel producing microorganisms. In certain embodiments, polysaccharide-producing, photosynthetic microorganisms are microalgae having frustules provide a substrate on which biofuel-producing microorganisms can grow. In other embodiments, the photosynthetic microorganisms produce a lipid and the non-photosynthetic microorganisms produce a solvent in which the lipid is soluble.
    Type: Application
    Filed: July 21, 2011
    Publication date: May 24, 2012
    Inventor: Pamela R. Contag
  • Patent number: 8178325
    Abstract: There is provided is a process for producing a sulfur-containing ?-hydroxycarboxylic acid compound represented by the formula (2): wherein R1 represents hydrogen, C1-8 alkyl, or C6-20 aryl, which comprises subjecting a sulfur-containing ketol represented by the formula (1): wherein R1 is the same as defined above, to the action of microbial cells of a microorganism belonging to the genus Pseudomonas, Rhodococcus or Bacillus capable of converting the ketol into a corresponding ?-hydroxycarboxylic acid compound, or a treated material thereof, thereby producing the sulfur-containing ?-hydroxycarboxylic acid without using a hydroxynitrile compound as a starting material.
    Type: Grant
    Filed: September 21, 2007
    Date of Patent: May 15, 2012
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Hiroyuki Asako, Koji Hagiya
  • Publication number: 20120100589
    Abstract: A method for treatment of a material comprising lignocellulosic fibres is disclosed. More particularly, the treatment increases the accessibility of the lignocellulosic fibres for following microbial or biological processes.
    Type: Application
    Filed: March 8, 2010
    Publication date: April 26, 2012
    Applicants: XERGI A/S, NOVOZYMES A/S
    Inventors: Danielle Rhine, Anders Peter Jensen, Stefan Borre-Gude
  • Publication number: 20120100094
    Abstract: The invention provides methods for providing Bacillus spores for application to agricultural soil or plant material as well as zootechnic applications for odor control in areas of high ammonia generation. The methods comprise suspending the Bacillus spores in a liquid consisting essentially of water and an organic acid, including acetic acid, wherein the acid lowers the pH so that the spores are inhibited from germination and growth; and so that growth of unwanted microorganisms in the suspension is prevented. Compositions formed according to the methods of the invention are also provided.
    Type: Application
    Filed: October 20, 2010
    Publication date: April 26, 2012
    Applicant: Osprey Biotechnics, Inc.
    Inventors: Christopher J. Reuter, Steven J. MacKenzie
  • Patent number: 8158402
    Abstract: A high-yield bacterial strain for producing acetoin named Bacillus pumilus XH195 has been deposited in a microorganism deposit center in Germany. The deposit number is DSM 16187. The bacteria of the strain are rod-shaped, 1.5 ?m to 3.0 ?m in length, and 0.6 ?m to 0.7 ?m in diameter. The colony color of the bacterial strain is yellow or white. The strain has the typical fatty acid profile of Bacillus and its physiological and biochemical characteristics align with those of Bacillus pumilus. When the bacteria of strain were cultured at 37° C. for 60 hours with shaking, the yield of acetoin could reach 63.0 g/L or 58.1 g/L, when glucose or sucrose was used as the substrate, respectively.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: April 17, 2012
    Assignee: Shanghai Apple Flavor & Fragrance Co., Ltd.
    Inventors: Ping Xu, Zijun Xiao, Yi Du, Zhonghao Wei
  • Patent number: 8148138
    Abstract: A seed treated with a fungal/bacterial antagonist combination and a seed assembly comprising a seed and a fungal/bacterial antagonist combination. The fungal/bacterial antagonist combination comprises a Trichoderma virens fungal antagonist and a Bacillus amyloliquefaciens bacterial antagonist for controlling plant pathogens as a biocontrol agent, bio-pesticide or bio-fungicide. In preferred embodiments, the invention produces an increase in plant yield. Control of early and late season stalk and root rot caused by fungi such as Fusarium, Phythium, Phytophthora and Penicillium in tomatoes, peppers, turf grass, soybeans, sunflower, wheat and corn is achieved.
    Type: Grant
    Filed: August 16, 2008
    Date of Patent: April 3, 2012
    Inventor: Thomas D. Johnson
  • Publication number: 20120076765
    Abstract: Six bacterial strains: Bacillus simplex strain 03WN13, Bacillus simplex strain 03WN23, Bacillus simplex strain 03WN25, Pseudomonas koreensis strain 10IL21, Pantoea agglomerans strain 10IL31, and Pseudomonas lini strain 13IL01, are superior antagonists of Phytophthora erythroseptica Pethybr., the causative agent of pink rot on potatoes. These bacterial strains are effective for suppression and control of pink rot on potatoes.
    Type: Application
    Filed: September 24, 2010
    Publication date: March 29, 2012
    Inventors: David A. Schisler, Patricia J. Slininger, Tugba Adiyaman
  • Publication number: 20120077181
    Abstract: The cryopreservation of cells and tissue cultures for long term storage of cells, cell constructs or three-dimensional complex tissues assemblies is based on the use of a collagen cell carrier (CCC) having a specific composition and thickness and appropriate mechanical properties which are maintained after thawing. The collagen cell carrier provides a suitable support for the cryopreservation resulting in high survival rates after thawing and providing cells and tissue assemblies already adhered to a mechanically stable and biocompatible support. Frozen collagen carrier-cells assemblies, the frozen artificial cell constructs or three-dimensional complex tissue assemblies obtainable by the method and the use thereof after thawing are also disclosed.
    Type: Application
    Filed: February 18, 2010
    Publication date: March 29, 2012
    Inventors: Timo Schmidt, Lothar Just, Franz Maser, Holger Becker
  • Publication number: 20120058531
    Abstract: The present invention concerns a new method for the production of 1,3-propanediol comprising culturing a microorganism on a culture medium with high glycerine content. The invention also concerns a new microorganism, or strain of microorganism, adapted for the production of 1,3-propanediol from medium comprising high glycerine content. The invention also concerns an “adapted microorganism” which glycerol metabolism is directed to 1,3-propanediol production, and which is allowed to grow in the presence of a high concentration of industrial glycerine. The invention also concerns a biosourced 1,3-propanediol obtained by the process thereof. Finally the invention concerns the use of the above described biosourced 1,3-propanediol as extender chain in thermoplastic polyurethane, as monomers in polytrimethylene terephtalate and as a component in cosmetics formulations.
    Type: Application
    Filed: May 5, 2010
    Publication date: March 8, 2012
    Applicant: METABOLIC EXPLORER
    Inventors: Michel Chateau, Jean-Yves Dubois, Philippe Soucaille
  • Patent number: 8124387
    Abstract: The invention relates to a process for the production of optically active Citronellal by enzymatic reduction of Citral with a reductase from Zymomonas mobilis.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: February 28, 2012
    Assignee: BASF SE
    Inventors: Rainer Stuermer, Thomas Friedrich, Andre Mueller, Bernhard Hauer, Bettina Rosche
  • Publication number: 20120045475
    Abstract: The present invention relates to a bacterium attenuated by a mutation in at least one ABC transporter gene wherein the mutation renders the corresponding ABC transporter protein non-functional and wherein the attenuated bacterium persists in a subject.
    Type: Application
    Filed: February 17, 2010
    Publication date: February 23, 2012
    Applicant: AUSTRALIAN POULTRY CRC PTY LIMITED
    Inventors: Glenn Francis Browning, Philip Francis Markham, Chi-Wen Tseng
  • Patent number: 8114648
    Abstract: The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: February 14, 2012
    Assignees: The Scripps Research Institute, The Regents of the University of California
    Inventors: Peter G. Schultz, Lei Wang, John Christopher Anderson, Jason W. Chin, David R. Liu, Thomas J. Magliery, Eric L. Meggers, Ryan Aaron Mehl, Miro Pastrnak, Stephen William Santoro, Zhiwen Zhang
  • Publication number: 20120028801
    Abstract: Aspects of the invention relate to organic biostimulant compositions, including, for example, formulations comprising corn steep liquor (CSL) and water. In certain illustrative embodiments, the organic biostimulant composition further comprises from one to five microbial strains as an inoculant. Another aspect of the invention relates to a method of cultivating plants that comprises the steps of preparing an organic biostimulant composition comprising water and CSL, and applying the organic biostimulant composition through a delivery system to a growth medium supporting plants.
    Type: Application
    Filed: July 30, 2010
    Publication date: February 2, 2012
    Inventor: Ralph S. Daniels
  • Publication number: 20120024795
    Abstract: A biosorbent for removing cationic and/or anionic metals from aqueous solutions, and a process for the production of the biosorbent. The biosorbent includes bacterial aggregates of Bacillus sp. VCHB-10, deposited as NRRL-B-30881, and treated with polyethyleneimine and glutaraldehyde. Among the metals in their cationic form, the following are considered: cations of Ag, Al, Au, Co, Cd, Cu, Cr, Fe, Hg, Mn, Ni, Pb, Pd, Pt, U, Th and Zn. Among the metals in their anionic form, the following are considered: anions of As, Cr and Mo. Removal or recovery of metals from wastewater using the biosorbent is also described.
    Type: Application
    Filed: May 11, 2011
    Publication date: February 2, 2012
    Applicants: BIOTECNOLOGIA DEL AGUA LTDA., UNIVERSIDAD DE CHILE
    Inventors: Davor Cotoras Tadic, Pabla Viedma, Juan Manuel Gajardo Sandoval
  • Patent number: 8105592
    Abstract: The present invention relates to heavy chain immunoglobulins or fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof, suitable for use in the management of infections, in particular of the gastrointestinal tract. The present invention also relates to a delivery system comprising these heavy chain immunoglobulins or functional fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof, and hosts comprising expression vectors encoding for these heavy chain immunoglobulins or functional fragments thereof of the VHH or VNAR type, or domain antibodies (dAbs) of the heavy or light chains of immunoglobulins or fragments thereof. The invention also relates to food products and pharmaceutical preparations comprising the delivery system, and methods for the preparation of food products according to the invention.
    Type: Grant
    Filed: November 3, 2005
    Date of Patent: January 31, 2012
    Assignee: VHsquared Limited
    Inventors: Leo Gerardus Joseph Frenken, Lars-Gõran Lennart Hammarström, Adrianus Marinus Ledeboer
  • Publication number: 20120021004
    Abstract: A new strain of Bacillus anthracis derived from the Sterne vaccine strain of Bacillus anthracis by growth on a high-nitrate-concentration, 3-amino-L-tyrosine growth medium.
    Type: Application
    Filed: May 25, 2007
    Publication date: January 26, 2012
    Inventors: Jill E. Parker, Johnathan L. Kiel, Homer Gifford, John L. Alls, Pedro J. Morales
  • Publication number: 20120015404
    Abstract: The invention belongs to the technical field of genetic engineering of agricultural microorganisms. Specifically, the invention relates to producing and using gene cluster for thuringiensin synthesis from Bacillus thuringiensis. The gene cluster includes 11 genes of thuA, thuB, thuC, thuD, thuE, thuF, thuG, thu1, thu2, thu3 and thu4. These genes have the nucleotide sequence as shown in SEQ ID NO: 1. And the thuringiensin biosynthetase encoded by these genes have the amino acid sequences as shown in SEQ ID NO: 2-12. The genes according to the invention and the proteins encoded by those genes can be used as new nucleosides lead compound of pesticide library and provide new target for developing insecticides. In practical use, a series of new, efficient and low toxic insecticide can be obtained by structure modification.
    Type: Application
    Filed: December 15, 2009
    Publication date: January 19, 2012
    Applicant: HUAZHONG AGRICULTURAL UNIVERSITY
    Inventors: Ming Sun, Ziniu Yu, Lifang Ruan, Shouwen Chen, Xiaoyan Liu, Donghai Peng