Lactobacillus, Pediococcus, Or Leuconostoc Patents (Class 435/252.9)
  • Patent number: 11066694
    Abstract: The present invention concerns compositions and processes that use affinity tags for isolating, and detecting or quantifying analytes, including nucleic acids, proteins and polypeptides. Compositions include nucleic acid compositions and protein compositions with affinity binding pairs, including metal binding peptides and immobilized metals, or peptide affinity groups.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: July 20, 2021
    Assignee: Enzo Biochem, Inc.
    Inventors: Elazar Rabbani, Jannis G. Stavrianopoulos, James J. Donegan, Wayne Patton, Juan Carcamo
  • Patent number: 10835485
    Abstract: The present invention is concerned with microorganisms or fragments thereof as sensorically neutral oral care agents, particularly for prevention of dental calculus, as anti-caries agents and/or anti-oral malodor agents. The invention is furthermore concerned with compositions comprising microorganisms or fragments thereof for reducing mutans Streptococci. Such compositions can be used in oral care compositions, e.g. for caries prophylaxis, or for prophylaxis of dental calculus or oral malodor. They may also or instead be used for prevention or treatment of oral malodor. As the microorganisms and fragments thereof according to the present invention have a very low, unobtrusive smell and taste, they are particularly suited as sensorically neutral agents for preventment of dental calculus, caries, oral biofilm formation and/or for prevention or treatment of oral malodor.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: November 17, 2020
    Assignee: BASF SE
    Inventor: Markus Pompejus
  • Patent number: 10188684
    Abstract: The present invention provides a method for preventing or treating a functional gastrointestinal disorder in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. The present invention further provides a method for preventing or treating visceral hypersensitivity in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. Moreover, the present invention provides a method for preventing or treating functional abdominal pain, irritable bowel syndrome or constipation in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: January 29, 2019
    Assignee: National Yang-Ming University
    Inventors: Ying-Chieh Tsai, Jian-Fu Liao, Chih-Chieh Hsu
  • Patent number: 9854822
    Abstract: Microbial starter cultures. More specifically, a method for preparing a microbial starter culture wherein the microorganism is inoculated in a culture medium comprising at least one 5 yield enhancing agent selected from the group consisting of a purine base, a pyrimidine base, a nucleoside and a nucleotide. Such microbial starter cultures are useful in the manufacturing of food, feed and pharmaceutical products.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: January 2, 2018
    Assignee: CHR. HANSEN A/S
    Inventors: Børge Windel Kringelum, Niels Martin Sørensen, Christel Garrigues, Martin B. Pedersen, Susanne Grøn
  • Patent number: 9839656
    Abstract: A composition comprising specific Lactobacillus helveticus strains is provided for reducing the symptoms of allergies originating from food, respiratory or contact allergens. Preferably the composition reduces symptoms of allergies (secondary prevention) while also able to reduce sensitization (primary prevention).
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: December 12, 2017
    Assignee: Nestec S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Marietta Weiss, Adrian Walter Zuercher
  • Patent number: 9771624
    Abstract: The multiple embodiments described herein comprise the genome of a probiotic Bifidobacterium longum bifidobacteria strain and genes encoded by the genome. Various novel Bifidobacterium longum are described.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: September 26, 2017
    Assignee: The Procter & Gamble Company
    Inventors: Douwe Van Sinderen, Jun Xu, Wenzhu (Steven) Zhao, Raymond A. Grant, Song Yuli, Charles Bascom, Duane Larry Charbonneau, Liam O'Mahony
  • Patent number: 9737577
    Abstract: An object of the present invention is to provide a useful composition that contains a highly safe lactic acid bacterium or a component derived from this lactic acid bacterium. The present invention relates to a composition comprising at least one lactic acid bacterium selected from the group consisting of Lactobacillus delbrueckii subsp. lactis strain KR-037 (NITE BP-395), Lactobacillus delbrueckii subsp. lactis strain KLAB-4 (NITE BP-394), and variants thereof, or comprising a component derived from the lactic acid bacterium. The composition of the present invention is useful as a preparation that has an excellent antiallergic function and also has at least one other function selected from an anti-autoimmune disease function, a diabetes-improving function, a neutral fat-lowering function, and so forth.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: August 22, 2017
    Assignee: KANEKA CORPORATION
    Inventors: Airo Tategaki, Toyoaki Watanabe, Kazuya Hamada
  • Patent number: 9629883
    Abstract: The present invention discloses different specific bacterial strains isolated from individuals without caries which are characterized in that they present inhibitory activity against cariogenic organisms. The invention also discloses a process for isolating said strains, as well as bioactive peptides, such as anti-microbial peptides of human and bacterial origin, which also show anti-cariogenic activity. Moreover, the present invention also discloses pharmaceutical and/or probiotic/prebiotic compositions, functional foods, mouthwashes, toothpaste, chewing gum, etc., that comprise at least one of the strains and/or at least one of the bioactive peptides described in the invention, or a combination thereof, which are useful in the treatment and/or prevention of infectious diseases of the buccal cavity, preferably caries.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: April 25, 2017
    Assignee: CENTRO SUPERIOR DE INVESTIGACIÓN EN SALUD PÚBLICA (CSISP)
    Inventor: Alejandro Mira Obrador
  • Patent number: 9185927
    Abstract: The present invention relates to a selected strain of Lactobacillus pentosus for use as a medication for the preventive or curative treatment of infections due to Gram-negative bacteria, preferably enterococci, coliforms and E. coli.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: November 17, 2015
    Assignee: Probiotical S.p.A.
    Inventors: Giovanni Mogna, Gian Paolo Strozzi, Luca Mogna
  • Patent number: 9169499
    Abstract: An engineering method was developed to allow genetic modification and isolation of lactic acid bacteria cells that lack lactate dehydrogenase and acetolactate decarboxylase activities. In cells with these modifications and an isobutanol biosynthetic pathway, improved production of isobutanol was observed.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: October 27, 2015
    Assignee: BUTAMAX ADVANCED BIOFUELS LLC
    Inventors: Brian James Paul, Wonchul Suh
  • Patent number: 9101651
    Abstract: The present invention generally relates to the field of obesity. In particular the present invention relates to the use of probiotics to treat obesity. One embodiment of the present invention relates to the use of Lactobacillus rhamnosus CGMCC 1.3724 and/or Lactobacillus rhamnosus NCC 4007 for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity.
    Type: Grant
    Filed: April 10, 2013
    Date of Patent: August 11, 2015
    Assignee: Nestec S.A.
    Inventors: Christian Darimont, David Philippe, Catherine Mace, Fabrizio Arigoni
  • Patent number: 9101158
    Abstract: The present invention addresses the problem of providing a soybean-derived raw material-containing food or beverage that improves problems with flavor and physical properties, such as the grassy smell caused by soybean raw materials, and markedly improves product quality, in a soybean-derived raw material-containing food or beverage using conventional soybean raw materials such soymilk or tofu. Provided are a milk-substitute composition, and an egg-yolk substitute composition, etc., characterized by including a soybean emulsion composition having a protein content relative to dry material of at least 25 wt %, a fat content (as a chloroform/methanol mixed solvent extract) relative to the protein content of at least 100 wt %, and an LCI value of at least 55%. Also provided are a variety of soybean-derived raw material-containing food and beverages using these compositions.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: August 11, 2015
    Assignee: FUJI OIL COMPANY LIMITED
    Inventors: Masahiko Samoto, Jiro Kanamori, Norifumi Adachi, Chizuru Ueno, Eriko Harada, Mai Kanda, Takahiro Tsuruda, Ayako Ogama, Yuki Usui, Koichi Saito, Kohsuke Ito, Hideo Sugano, Masashi Asanoma, Mitsutaka Kohno, Masayuki Shibata, Yuusuke Shishido, Sayuri Kitagawa, Miyuki Kanaya, Shigeru Ashida, Takayasu Motoyama
  • Patent number: 9057112
    Abstract: The invention herein provides certain strains of lactic acid bacteria selected for their capability of promoting production of IL-10 and consequently proliferation of CD4+CD25+ TR cells, for prophylaxis and/or treatment of infant colic, a method of selecting such strains, and products containing such strains.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: June 16, 2015
    Assignee: BIOGAIA AB
    Inventors: Eamonn Connolly, Bo Mollstam
  • Patent number: 9040037
    Abstract: The present invention provides a triple vital bacteria composition, including: powder of Bifidobacterium longum, powder of Lactobacillus acidophilus, and powder of Streptococcus faecalis. The present invention further provides a method for preparing the above triple vital bacteria composition, as well as the protection agents, the fermenting culture medium and the seed culture medium used therein.
    Type: Grant
    Filed: February 3, 2008
    Date of Patent: May 26, 2015
    Assignee: Shanghai Sine Pharmaceutical Laboratories Co., Ltd.
    Inventors: Binhua Chen, Xuesong Wang, Liang Zhang
  • Publication number: 20150139968
    Abstract: The present invention relates to a composition used for treating picornavirus infection comprising at least one of the following bacterial strains: Lactobacillus paracasei GMNL-33 with the deposition numbers of CCTCC M 206133, Lactobacillus reuteri GMNL-89 with the deposition numbers of CCTCC M 207154 and Lactobacillus casei GMNL-277 with the deposition numbers of CCTCC M 2013197, and a pharmaceutically acceptable vehicle. The Lactobacillus casei GMNL-277 of the invention is a novel Lactobacillus isolated strain. In addition, the present invention also features the novel use of the composition of the Lactobacillus strains for treating picornavirus infection, and the mechanism of which is inhibition of virus infection by binding of the probiotic bacteria to viruses.
    Type: Application
    Filed: November 15, 2013
    Publication date: May 21, 2015
    Applicant: GENMONT BIOTECH INC.
    Inventors: Ya-Fang Wang, Jen-Ren Wang, Yi-Hsing Chen
  • Publication number: 20150132270
    Abstract: The present invention relates to novel strains of Lactobacillus as well as preparations and compositions, such as fermentation broths, protective cultures, final food or feed product with Lactobacillus alone or in combination with bacteria of the genus Propionibacterium. The present invention further relates to methods for the controlling of growth of a contaminant, such as a bacteria, yeast or mould by using these novel strains of Lactobacillus.
    Type: Application
    Filed: May 21, 2013
    Publication date: May 14, 2015
    Inventors: Connie Benfeldt, Heike Ursula Morgenstern
  • Patent number: 9011877
    Abstract: TRFs useful for identifying strains of interest are provided. A method of identifying one or more strain that can be used as a direct-fed microbial is also provided. One or more strain identified by the method is additionally provided. A method is also provided for administering to an animal an effective amount of the one or more strain. Additionally provided is an isolated strain chosen from at least one of Lactobacillus acidophilus strain P1B c6 (NRRL B-50103), Lactobacillus salivarius strain o246e 33w (NRRL B-50102), Pediococcus acidilactici strain o246e 42 (NRRL B-50171), and Pediococcus acidilactici strain P1J e3 (NRRL B-50101). An isolated strain having all of the identifying characteristics of one of the strains listed above is also provided. One or more strain can be administered as a direct-fed microbial to an animal. Methods of preparing a direct-fed microbial are also provided.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: April 21, 2015
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Mari Ellen Davis, Joshua M. Rehberger, Charles Maxwell, Thomas G. Rehberger, Mike King
  • Patent number: 9011838
    Abstract: Methods and compositions are hereby disclosed for reducing the numbers of E. coli O157:H7, Salmonella or other pathogens in an animal. The methods include administering to the animal a lactic acid producing bacterium at a relatively low dosage in combination with a lactate utilizing bacterium, followed by administration of the lactic acid producing bacterium at a relatively high dosage. The disclosed methods help achieve pre-harvest food safety and enhance feed performance while keeping the total cost relatively low. The preferred lactic acid producing bacterium is Lactobacillus acidophilus/animalis and the preferred lactate utilizing bacterium is Propionibacterium freudenreichii.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: April 21, 2015
    Assignee: Nutrition Physiology Company, LLC
    Inventors: Douglas Ware, Peter Anderson
  • Patent number: 8986675
    Abstract: The present invention relates to the prevention and treatment of obesity and obesity related metabolic syndrome, particularly to the prevention and treatment of obesity by changing intestinal flora. The characteristics of intestinal bacteria are transformed by administration of a microorganism preparation which improves free fatty acid absorption by the bacteria, and free fatty acid absorption in the gastrointestinal tract is thereby decreased by introduction thereof. The present invention provides a method for preventing and treating obesity and obesity related metabolic syndrome, a pharmaceutical composition and diet supplement for prevention and treatment thereof, and modified probiotic strains usable for such purposes. The present invention provides a weight loss effect and shows that the absorption of fatty acids in the gastrointestinal tract is blocked by improving the characteristics of intestinal bacteria and transplanting them, thereby enabling the treatment of obesity.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: March 24, 2015
    Assignee: Jinis Biopharmaceuticals Co.
    Inventors: Hyeon Jin Kim, Seong Tshool Hong
  • Publication number: 20150079040
    Abstract: The invention provides probiotic bacteria and lysates thereof for use in methods of medical and cosmetic treatment. Use in the treatment of infections, including skin infections and methods involving regeneration or repair of the skin barrier are contemplated.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 19, 2015
    Inventors: Catherine O'Neill, Andrew McBain
  • Publication number: 20150079057
    Abstract: The present invention is related to the field of bioprotection, in particular to the strain of Lactobacillus rhamnosus CHCC5366 with accession no. DSM23035. Furthermore, the present invention concerns an antifungal composition comprising the strain, an antifungal composition comprising the strain and at least one strain of Lactobacillus paracasei, food, feed and pharmaceutical products comprising such an antifungal composition, a method of manufacturing such food, feed and pharmaceutical products, a method for reducing the content of yeasts and molds of such food, feed and pharmaceutical products and uses of the antifungal composition.
    Type: Application
    Filed: April 9, 2013
    Publication date: March 19, 2015
    Applicant: CHR. HANSEN A/S
    Inventors: Tina Hornbaek, Maike Lisberg, Silja Kej Diemer
  • Publication number: 20150079236
    Abstract: The present invention relates to food-grade bacteria strain being capable of removing mercury from an aqueous environment.
    Type: Application
    Filed: April 5, 2013
    Publication date: March 19, 2015
    Inventors: Jeremy Burton, Marc Monaches, Gregor Reid, Tamara Smokvina, Johan Van Hylckama Vlieg
  • Publication number: 20150079232
    Abstract: The present invention relates to mutants of lactic acid bacteria which are resistant to the antibiotic ampicillin and which were found to give an increased texture when grown in milk while maintaining the other growth properties of the parent strain. The present invention, furthermore, relates to compositions comprising such mutants, and to dairy products fermented with the lactic acid bacteria resistant to ampicillin.
    Type: Application
    Filed: April 23, 2013
    Publication date: March 19, 2015
    Applicant: Chr. Hansen A/S
    Inventors: Eric Johnsen, Kim Ib Soerensen, Annette Kibenich
  • Patent number: 8980611
    Abstract: Compositions and methods useful for reducing or eliminating the presence of pathogens in meat or meat products are disclosed. Administration of one or more lactic acid producing microorganisms to a live animal, to a carcass, to meat, to meat products, or in animal feed results in significant reductions in the amount of pathogens potentially harmful to humans when ingested. Synergistic effects can be achieved with the administration of multiple strains of microorganisms.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: March 17, 2015
    Assignee: Guardian Food Technologies, LLC
    Inventors: Douglas R. Ware, Mindy M. Brashears
  • Publication number: 20150072033
    Abstract: The present invention generally relates to the field of pro biotic micro-organisms, in particular to the field of non-replicating probiotic micro-organisms. Embodiments of the present invention relate to compositions comprising probiotic microorganisms that were rendered non-replicating by extrusion. Such compositions may be used to treat or prevent disorders that are related to a compromised immune system.
    Type: Application
    Filed: November 14, 2014
    Publication date: March 12, 2015
    Inventors: Annick Mercenier, Antoine Wermeille, Audrey Demont, Guenolee Prioult
  • Publication number: 20150064152
    Abstract: The present invention is related to the field of bioprotection, in particular to the strain of Lactobacillus paracasei CHCC14676 with accession no. DSM25612. Furthermore, the present invention concerns an antifungal composition comprising the strain, an antifungal composition comprising the strain and at least one strain of Lactobacillus rhamnosus, food, feed and pharmaceutical products comprising such an antifungal composition, a method of manufacturing such food, feed and pharmaceutical products, a method for reducing the content of yeasts and molds of such food, feed and pharmaceutical products and uses of the antifungal composition.
    Type: Application
    Filed: April 9, 2013
    Publication date: March 5, 2015
    Applicant: Chr. Hansen A/S
    Inventors: Tina Hornbaek, Maike Lisberg, Silja Kej Diemer
  • Patent number: 8961953
    Abstract: This invention relates to a preparation comprising N-acetyl-lactosamine and/or an oligosaccharide containing N-acetyl-lactosamine and a probiotic Lactobacillus sp. The invention extends to nutritional compositions comprising said preparation and to the use of the preparation in the prevention and treatment of pathogenic infections of the gastro-intestinal and upper respiratory tracts.
    Type: Grant
    Filed: February 24, 2009
    Date of Patent: February 24, 2015
    Assignee: Nestec S.A.
    Inventor: Norbert Sprenger
  • Publication number: 20150050254
    Abstract: A first aspect of the invention relates to a porcine lactic acid bacterial strain, wherein said bacterial strain is characterised by one or more of the following characteristics: (i) the ability to exhibit antimicrobial activity against E. coli; (ii) the ability to exhibit antimicrobial activity against S. enteritidis; (iii) the ability to suppress inflammation in IPEC cells induced by 12-0-tetradecaboylphorbol-13-acetate (PMA); (iv) the ability to block the attachment or invasion of IPEC cells by S. enteritidis; (v) the ability to block the attachment or invasion of IPEC cells by E. coli; (vi) the absence of antibiotic resistance to one or more antibiotics selected from the following: ampicillin; cefotaxime; chloramphenicol; erythromycin; gentamicin; tetracycline; vancomycin; metronizadole; nalidixic acid; and kanamycin; and (vii) the ability to exhibit heat stability when subjected to three cycles of heating, each cycle comprising heating at a temperature of 70° C. for a period of 15 minutes.
    Type: Application
    Filed: July 13, 2012
    Publication date: February 19, 2015
    Applicant: GT BIOLOGICS LTD
    Inventor: Denise Kelly
  • Publication number: 20150050255
    Abstract: New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower LDL-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation.
    Type: Application
    Filed: October 28, 2014
    Publication date: February 19, 2015
    Inventors: BELINDA VALLEJO GALLAND, AARÓN FERNANDO GONZÁLEZ CÓRDOVA, JÓSE CARLOS RODRÍGUEZ FIGUEROA
  • Patent number: 8951775
    Abstract: The present invention relates to the cosmetic use of an effective amount of at least one probiotic microorganism and/or a fraction thereof and/or a metabolite thereof, as an agent for treating and/or preventing oily skin or skin with an oily tendency and the associated skin disorders.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: February 10, 2015
    Assignees: L'Oreal, Nestec SA
    Inventors: Isabelle Castiel, Audrey Gueniche
  • Patent number: 8945534
    Abstract: Methods for the controlled activation of the reuterin-production machinery of Lactobacillus reuteri by adding glycerol and other substances during the manufacture of cell-cultures and keeping the produced reuterin in the bacterial cell during preservation and storage. In particular this invention relates to the manufacture of large amounts of L. reuteri that are loaded with reuterin, and the use of such loaded bacteria for applications such as prevention and treatment of diseases, for food applications and the like.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: February 3, 2015
    Assignee: BioGaia AB
    Inventor: Stefan Roos
  • Patent number: 8936928
    Abstract: The present invention provides probiotic compositions suitable for reducing the incidence and duration of nasal eosinophilia and other parameters associated with birch pollen allergy. In some embodiments, the present invention provides methods and/or compositions suitable for reducing nasal and/or respiratory allergy symptoms. Suitably, such compositions may comprise L. acidophilus, B. lactis or both.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: January 20, 2015
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Arthur Ouwehand, Nina Rautonen, Seppo Jaakko Salminen, Erika Isolauri
  • Patent number: 8927253
    Abstract: This disclosure relates to enhancing growth and/or activity of lactobacilli using a prebiotic formulation which includes iso-malto oligosaccharides and ?-galactosidase; and to enhancing growth and/or activity of bifidobacteria using a prebiotic formulation which includes iso-malto oligosaccharides and ?-glucanase. Other combinations of fibers and enzymes are described below which also stimulate growth and activity of lactobacilli or bifidobacteria. These combinations of enzymes and prebiotics can be taken separately or added to foods, including desserts.
    Type: Grant
    Filed: September 7, 2013
    Date of Patent: January 6, 2015
    Assignee: Master Supplements, Inc.
    Inventors: Randolph S. Porubcan, Sonja L. Yonak
  • Patent number: 8927252
    Abstract: The present invention relates to synbiotic compositions comprising probiotic bacterial strains and prebiotic substances that, when combined exhibit synergistic behavior. The synergetic compositions will stimulate the indigenous microflora to restore and reconstitute in vivo gut like conditions after antibiotic associated diarrhea (AAD), and/or other gut infections caused by gastrointestinal pathogens, and relapses thereof, as well as the prevention of said disorders.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: January 6, 2015
    Assignee: Lavivo AB
    Inventors: Torkel Wadström, Asa Ljungh, Padma Ambalam, Kanthi Kiran Kondepudi
  • Patent number: 8921060
    Abstract: The invention relates to the area of health-beneficial preparations and production methods thereof, in particular to the use of thermally pre-treated Lactobacillus preparations having specific bonding capacity for Streptococcus mutans for caries prophylaxis. The invention further relates to the Lactobacillus preparations and thermal pasteurization.
    Type: Grant
    Filed: October 11, 2010
    Date of Patent: December 30, 2014
    Assignee: BASF SE
    Inventor: Bryan Cooper
  • Patent number: 8916374
    Abstract: The present invention relates to the field of infant cereals. In particular, the present invention relates to the field of infant cereals that can be used to strengthen the immune system of the infant and/or that can be used to treat or prevent inflammatory disorders. For example these benefits can be provided by probiotic micro-organisms. An embodiment of the present invention relates to an infant cereal comprising non-replicating probiotic-micro-organisms, for example bioactive heat treated probiotic micro-organisms.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: December 23, 2014
    Assignee: Nestec S.A.
    Inventors: Annick Mercenier, Sophie Nutten, Guenolee Prioult
  • Publication number: 20140369981
    Abstract: The Lactobacillus plantarum CCFM8661 is tolerant to acid and lead ions in vitro which can tolerate lead ions solution with the initial concentration of 150 mg/L, and has a strong capability of binding lead ions, which can reduce the lead level in mice blood, liver, kidney and stomach, significantly improve antioxidant indicators and alleviate pathological symptoms of lead exposed mice.
    Type: Application
    Filed: July 18, 2012
    Publication date: December 18, 2014
    Applicant: Jiangnan University
    Inventors: Fengwei Tian, Wei Chen, Qixiao Zhai, Hao Zhang, Jianxin Zhao, Gang Wang, Yuanda Song, Qiuxiang Zhang, Xiaoming Liu, Min Guo, Daming Fan
  • Publication number: 20140363501
    Abstract: An anti-oxidative Lactobacillus rhamnosus CCFM1107 can relieve chronic alcoholic liver injury, and L. rhamnosus CCFM1107 can be used in preparing dairy products as starter culture. The dairy products of this invention include milk, milk powder, milk capsules or fermented milk containing L. rhamnosus CCFM1107. It has strong abilities of anti-oxidation, scavenging diphenyl picrylhydrazyl (DPPH) radical and hydroxyl radical, inhibiting lipid peroxidation, tolerating cholate, chlorine sodium and pH, and can improve liver function and antioxidative index, lower serum endotoxin level and regulate intestinal flora distribution, thus effectively relieving alcoholic liver injury of mice.
    Type: Application
    Filed: July 19, 2012
    Publication date: December 11, 2014
    Applicant: Jiangnan University
    Inventors: Wei Chen, Fengwei Tian, Wenli Huang, Jianxi n Zhao, Hao Zhang, Gang Wang, Qiuxiang Zhang, Xiaoming Liu, Daming Fan, Feifei Chi
  • Publication number: 20140363410
    Abstract: The invention relates to Lactobacillus reuteri DSM 17938 for promoting the establishment of healthy and normal cognitive function in young mammals. In particular, the invention relates to the use of Lactobacillus reuteri DSM 17938 for promoting development of the brain structures responsible for cognitive functions (e.g. cortex and hippocampus) and its associated neural pathways and/or to reverse retardation and/or to prevent retardation of the establishment of cognitive functions. Humans or animals and, in particular, a foetus, pre-term or term born infant, toddler or child or a young adult may benefit from the invention.
    Type: Application
    Filed: November 30, 2012
    Publication date: December 11, 2014
    Applicant: BioGaia AB
    Inventors: Gabriela Bergonzelli Degonda, Magali Faure, Nicole Kusy
  • Publication number: 20140363880
    Abstract: Disclosed are: a lactic acid bacterium belonging to Lactobacillus kunkeei, the bacterium having a higher IgA production inducing activity than that of Lactobacillus strain GG (ATCC53103), and a lower mitogenic activity and a lower IL-2 production inducing activity than those of Listeria strain EGD; and a food composition, a pharmaceutical composition, a cosmetic composition, an immunostimulant for preventing the infection by pathogens or viruses that invade through the respiratory or esophageal mucosa, and an intestinal immunostimulant for preventing or alleviating food poisoning, each of which contains the lactic acid bacterium or treated cells of the lactic acid bacterium.
    Type: Application
    Filed: December 25, 2012
    Publication date: December 11, 2014
    Applicant: Yamada Bee Company
    Inventors: Daisuke Matsuura, Takashi Asama, Hironori Motoki, Tomoki Tatefuji, Ken Hashimoto
  • Publication number: 20140356338
    Abstract: Disclosed are a rice-fermented food composition which contains a rice saccharified liquid fermented with kimchi lactic acid bacteria as an active ingredient and has antibacterial and antiviral effects. More particularly, the present invention relates to a rice lactic acid bacteria fermented food composition which is prepared by adding kimchi lactic acid bacteria to a rice saccharified liquid as a main ingredient and fermenting the mixture, and has antibacterial and antiviral effects against atopic dermatitis and avian influenza virus, and a functional health food comprising the same.
    Type: Application
    Filed: May 12, 2011
    Publication date: December 4, 2014
    Inventors: Yong-Ha Park, Jeong-Heui Lim, Byoung-Joo Seo
  • Publication number: 20140356329
    Abstract: The present invention provides probiotic compositions suitable for reducing the incidence and duration of human illness. In particular, the present invention provides methods and compositions suitable for preventing disease in young children. In some particularly preferred embodiments, the present invention finds use in the prevention respiratory disease in children.
    Type: Application
    Filed: August 14, 2014
    Publication date: December 4, 2014
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: Gregory Leyer, Arthur Ouwehand
  • Patent number: 8900570
    Abstract: The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors. Phospholipids may also be an effector. The novel treatment strategy is capable of removing the symptoms of inflammatory bowel diseases regardless of a mild, moderate or severe stage of the disease.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 2, 2014
    Assignee: Nordisk Rebalance A/S
    Inventor: Hans Israelsen
  • Publication number: 20140348878
    Abstract: A strain of exopolysaccharide-secreting Lactobacillus brevis, BDLB0001, and an application thereof. The Lactobacillus brevis is deposited at the China General Microbiological Culture Collection Center of the China Committee of Culture Collection for Microorganisms, with a deposit number of CGMCC No. 5223. The Lactobacillus brevis secrets an elevated amount of exopolysaccharide, where the exopolysaccharide secreted is capable of eliciting B lymphocyte proliferation to enhance immunity, and has application prospects in medicaments, healthcare products and food products for immunity enhancement.
    Type: Application
    Filed: April 25, 2012
    Publication date: November 27, 2014
    Applicant: BRIGHT DAIRY & FOOD CO., LTD.
    Inventors: Lianzhong Ai, Benheng Guo, Kejie Sun, Wei Chen, Hao Zhang, Li Shao, Zhengjun Wu, Wanyi Chen, Haibo Mu
  • Publication number: 20140348978
    Abstract: The present invention relates to a method for producing cheese with good flavour, especially low-salt cheese by using a lactic acid bacteria (LAB) starter culture which is glutamate decarboxylation (GAD) negative. The method may additionally involve inoculating the milk substrate with a GAD-negative Lb. helveticus strain having a high lytic and peptidolytic activity, which further releases glutamate into the milk Additional application of camel chymosin reduces bitterness.
    Type: Application
    Filed: December 21, 2012
    Publication date: November 27, 2014
    Inventors: Kirsten Kastberg Moeller, Fergal Rattray, Erik Hoeier, Yiva Ardoe
  • Patent number: 8894991
    Abstract: According to the invention there is provided a strain of lactic acid bacteria of the genus Lactobacilli obtainable by isolation from resected and washed canine gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Lactobacilli of the present invention are also provided.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: November 25, 2014
    Assignee: The Iams Company
    Inventors: Thomas William-Maxwell Boileau, Michael Anthony Ceddia, John Kevin Collins, Gary Mitchell Davenport, Barry Pius Kiely, Liam Diarmuid O'Mahony, Gregory Dean Sunvold, Mark Alan Tetrick, Robert Jason Vickers
  • Publication number: 20140341855
    Abstract: The invention relates to reuterin-producing strains of Lactobacillus brevis. These strains are useful in particular for the treatment or the prevention of conditions resulting from Helicobacter pylori infection.
    Type: Application
    Filed: November 30, 2011
    Publication date: November 20, 2014
    Applicant: COMPAGNIE GERVAIS DANONE
    Inventors: Peggy Garault, Gaelle Quere, Raphaelle Bourdet-Sicard
  • Publication number: 20140341873
    Abstract: The invention provides a novel strain of cadmium-removing Lactobacillus plantarum bacterium, CCFM8610, which has a good tolerance to acidic environments. Lactobacillus plantarum CCFM8610 has a good tolerance to cadmium-containing medium and can effectively bind cadmium in vitro. Animal studies have shown that it can effectively reduce tissue cadmium accumulation and facilitate fecal cadmium excretion. Lactobacillus plantarum CCFM8610 has a great potential to be used as an active ingredient in cadmium-removing pharmaceutical drugs and fermented foods.
    Type: Application
    Filed: December 7, 2012
    Publication date: November 20, 2014
    Inventors: Wei Chen, Fengwei Tian, Qixiao Zhai, Gang Wang, Xiaoming Liu, Qiuxiang Zhang, Daming Fan, Jianxin Zhao, Hao Zhang
  • Patent number: RE46718
    Abstract: The invention refers to a composition comprising one or more tannase-producing strains of Lactobacillus having the ability to adhere to the human intestinal mucosa in combination with tannin. New tannase-producing strains of Lactobacillus plantarum are a.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: February 20, 2018
    Assignee: Probi AB
    Inventors: Goran Molin, Siv Ahrné, Bengt Jeppsson
  • Patent number: RE48652
    Abstract: The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well. Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: July 20, 2021
    Assignee: BIONEER CORPORATION
    Inventors: Ji Hee Kang, Byeung Il You, Sung Il Yun, Han Oh Park