Lactobacillus, Pediococcus, Or Leuconostoc Patents (Class 435/252.9)
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Patent number: 12194067Abstract: The respiratory microbiomes of neonates and those with bronchopulmonary disease have been characterized. Provided are probiotic compositions, which can include at least one living bacterial strain and at least one killed bacterial strain, that can comprise a combination of Lactobacilli species, that when delivered to the bronchi or lungs of a patient can provide a reduction in the symptoms of a bronchopulmonary disease.Type: GrantFiled: July 31, 2023Date of Patent: January 14, 2025Assignee: The UAB Research FoundationInventors: Charitharth Vivek Lal, Namasivayam Ambalavanan, Amit Gaggar, Casey Morrow
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Patent number: 12186351Abstract: Disclosed herein is a composition for modulating immunity, comprising Lactobacillus paracasei LT12, ?-glucan, and Bovine Colostrum Powder. Also provided is a method for modulating immunity, comprising administering to a subject in need a therapeutically effective amount of the composition, wherein the method is to enhance the expression of IL-6, IL-10, TNF-? and TGF-?1.Type: GrantFiled: December 13, 2021Date of Patent: January 7, 2025Assignee: LYTONE ENTERPRISE, INC.Inventors: Chia-Shin Ho, Wei-Ting Chang, Wei-Ting Tseng, Tien-Hung Chang
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Patent number: 12180306Abstract: The invention provides an anti-allergic peptide and a use thereof for immune regulation and anti-allergy, the anti-allergic peptide is capable of inhibiting secretion of cytokines related to allergic reactions and regulating allergic reactions, and the anti-allergic peptide comprises an amino acid sequence shown in SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 4 or SEQ ID No: 5, or a homologous amino acid sequence derived from substitution, deletion, and addition of one amino acid or more than one amino acid of any of the above sequences.Type: GrantFiled: December 2, 2022Date of Patent: December 31, 2024Assignee: GREENYN BIOTECHNOLOGY CO., LTDInventors: Pang Kuei Hsu, Yu Cheng Lin, Chih Kuo Kao, Chia Feng Wu
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Patent number: 12180459Abstract: The present invention relates to a novel Kazachstania turicensis CAU Y1706 and a composition using same, and more specifically, to a Kazachstania turicensis CAU Y1706 (Accession No.: KCTC13794BP) strain, and a pharmaceutical composition, a food composition, a cosmetic composition, and a probiotic composition for preventing or treating inflammatory diseases, comprising the strain or a culture thereof as an active ingredient.Type: GrantFiled: January 23, 2020Date of Patent: December 31, 2024Assignee: CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATIONInventors: Won Yong Kim, Jong Hwa Kim, Ki Young Kim, Kanjanasuntree Rungravee
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Patent number: 12109195Abstract: Compositions and methods for treatment and prevention of vaginal infections where the compositions include creatinine, such as protonated creatinine or creatinine salts, and optionally one or more weak acids, such as boric acid. The compositions may be used to treat and/or prevent a vaginal infection, such as bacterial vaginosis, to prevent recurrence of a vaginal infection, to treat and/or prevent a sexually transmitted disease (STD) or sexually transmitted infection (STI), and reduce the incidence and/or risk of a subject transmitting a STI or STD.Type: GrantFiled: June 30, 2021Date of Patent: October 8, 2024Assignee: Vireo Systems, Inc.Inventors: Mark C. Faulkner, Deeannah Seymour
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Patent number: 11963986Abstract: The application discloses Lactobacillus strains having a beneficial effect on the metabolic health on a mammalian subject. Further disclosed is compositions comprising such strains and the use thereof for improving the metabolic health or for lowering the blood glucose level in a mammalian subject.Type: GrantFiled: October 24, 2019Date of Patent: April 23, 2024Assignee: Novozymes A/SInventors: Nanna Ny Kristensen, Alexandra Mattern, Delphine Marie Anne Saulnier, Jeffrey Schultchen, Teis Jensen, Benjamin Anderschou Holbech Jensen
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Patent number: 11938156Abstract: An isolated and purified lactic acid bacteria is provided, which is Lactobacillus paracasei PS23 (PS23) and its applications in delaying aging process, improving immunomodulatory activity, reducing, preventing or treating allergic and inflammation, preventing or treating a chronic disorder and/or (vi) preventing and/or treating a mood disorder or a neurological condition.Type: GrantFiled: January 4, 2019Date of Patent: March 26, 2024Assignee: BENED BIOMEDICAL CO., LTD.Inventors: Ying-Chieh Tsai, Hui-Yu Huang, Chien-Chen Wu, Jyh-Shing Hsu
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Patent number: 11911422Abstract: A Bifidobacterium lactis BL-99 strain capable of enhancing immunity and the use thereof, which belongs to the technical field of microorganisms, is described. The Bifidobacterium lactis BL-99 provided by the present invention is deposited in China General Microbiological Culture Collection Center CGMCC on Apr. 26, 2018 with the deposit number CGMCC No. 15650. The bacteria have gastric acid resistance and intestinal fluid resistance, can significantly promote the growth of Bifidobacterium and Lactobacillus, significantly increase antibody-producing cells and half hemolysis value HC50, activate NK cell activity, and can be used to prepare foods for immunity enhancement. It also has the effects in preventing osteoporosis, increasing blood calcium and/or phosphorus ions, which has a wide range of application prospects.Type: GrantFiled: March 3, 2022Date of Patent: February 27, 2024Assignee: Inner Mongolia Yili Industrial Group Co., Ltd.Inventors: Wei-Hsien Liu, Wei-Lian Hung, Ting Sun, Wen Zhao, Ignatius Man-Yau Szeto
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Patent number: 11889835Abstract: The present invention relates to a plant growth regulator of elevating anti-stress ability and use thereof. The plant growth regulator, which is consisted of Lactobacillus fermenting culture solution, has excellent thermostability and safety without any side effect, significantly elevating ability against biotic and abiotic stresses. Therefore, the Lactobacillus fermenting culture solution can be applied as the plant growth regulator or a use in preparation of a composition for elevating anti-stress ability of a plant.Type: GrantFiled: March 25, 2019Date of Patent: February 6, 2024Assignee: GENMONT BIOTECH INCORPORATIONInventors: Yi-Hsing Chen, Wan-Hua Tsai, Tsuei-Yin Huang, Hsiang-En Huang, Yu-Jen Hsu
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Patent number: 11812770Abstract: The present application relates to a Lactobacillus paracasei or progeny thereof. Specifically, the present application relates to Lactobacillus paracasei 207-27 and a composition, culture, food product or dietary supplement containing the same. The present application also relates to the use of Lactobacillus paracasei 207-27 and the composition, culture, food product or dietary supplement containing the same in medicine.Type: GrantFiled: February 1, 2021Date of Patent: November 14, 2023Assignee: BYHEALTH CO., LTD.Inventors: Xuguang Zhang, Xiaolei Ze, Ruikun He, Fang He
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Patent number: 11660312Abstract: The present invention relates to a Bifidobacterium bifidum inducing regulatory T cells (Treg), a polysaccharide derived from Bifidobacterium bifidum, and a probiotic strain producing a polysaccharide and, more particularly, a polysaccharide containing ?-1-6-glucan as an effective ingredient, a probiotic strain producing ?-1-6-glucan, a food comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a therapeutic agent comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a method for preparing induced regulatory T cells (iTreg) by treatment with the polysaccharide or strain, and a cell therapy product for prevention or treatment of immune disease or inflammatory disease, comprising the induced regulatory T cells prepared by the method.Type: GrantFiled: June 14, 2018Date of Patent: May 30, 2023Assignees: INSTITUTE FOR BASIC SCIENCE, POSTECH ACADEMY-INDUSTRY FOUNDATIONInventors: Sin-Hyeog Im, Ravi Verma, Changhon Lee
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Patent number: 11653689Abstract: The present invention relates to Bifidobacterium breve deposited as DSM 32356 and compositions comprising said strain. The composition may further comprise at least one other bacterial strain and/or at least one compound which may be an NSAID such as acetylsalicylic acid (aspirin). In a presently preferred embodiment the invention relates to Bifidobacterium breve deposited as DSM 32356 for use in the support of the defense against intestinal tissue damage such as intestinal mucosal breaks or lesions e.g. in connection with NSAID administration such as in connection with administration of acetylsalicylic acid (aspirin). The invention further provides a method of supporting the defense against intestinal tissue damage, the method comprising administering the Bifidobacterium breve strain deposited as DSM 32356 to a subject in need thereof, e.g. to a subject in need of NSAID treatment.Type: GrantFiled: May 1, 2019Date of Patent: May 23, 2023Assignee: Chr. Hansen A/SInventors: Brynjulf Mortensen, Anders Damholt, Anja Wellejus, Vibeke Westphal Stennicke, Johan E. T. Van Hycklama Vlieg
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Patent number: 11638431Abstract: An object of the present invention is to provide a fermented milk and polysaccharide capable of inhibiting cancerous cachexia. A fermented milk with cancerous cachexia inhibitory effect according to one aspect of the present invention contains Lactobacillus delbrueckii subsp. bulgaricus as an active ingredient. Also, polysaccharide with cancerous cachexia inhibitory effect according to another aspect of the present invention are produced from the Lactobacillus delbrueckii subsp. bulgaricus. It is preferable that the Lactobacillus delbrueckii subsp. bulgaricus is Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 (accession number: FERM BP-10741).Type: GrantFiled: October 29, 2018Date of Patent: May 2, 2023Assignee: MEIJI CO., LTD.Inventors: Hirotaka Kawanabe, Marie Nakamura
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Patent number: 11591416Abstract: The present invention refers to exopolysaccharide molecules, conditioned media or compositions comprising said molecules or media. Moreover, the present invention refers to use of said exopolysaccharide molecules, conditioned media or compositions as prebiotic, preferably to boost immune system.Type: GrantFiled: December 1, 2017Date of Patent: February 28, 2023Assignee: SOFAR S.P.A.Inventors: Andrea Biffi, Ruggero Rossi, Walter Fiore, Simone Domenico Guglielmetti, Silvia Balzaretti
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Patent number: 11590182Abstract: Disclosed herein are methods and compositions related to probiotic formulas. These formulas comprise the bacterial strain Lactobacillus crispatus WZ-12 or a derivative thereof. Other strains which can be included in the composition include, but are not limited to, Lactobacillus salivarius 1-14, or Lactobacillus reuteri 2-2, and derivatives thereof. These compositions can be used in a variety of methods to treat and/or ameliorate diseases, such as colonization of antibiotic-resistant bacteria in the host organism. Also disclosed herein are methods of treating those subjects in need thereof by administering the compositions disclosed herein.Type: GrantFiled: September 10, 2019Date of Patent: February 28, 2023Assignee: Ohio State Innovation FoundationInventors: Hua Wang, Lu Zhang, Yang Zhou, Zihua Wang
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Patent number: 11541085Abstract: Disclosed herein is a process for producing a postbiotic extract, which includes providing a first material having a first isoelectric point ranging from pH 1 to pH 6 and a second material having a second isoelectric point ranging from pH 4 to pH 8, admixing the first material and a probiotic microorganism with water having a pH greater than the second isoelectric point, so as to form a mixture, adding the second material into the mixture and then adjusting a pH of the second material-added mixture to between the first and second isoelectric points so that a precipitate is formed, and subjecting the precipitate to a cell wall isolation treatment to obtain the postbiotic extract. Use of the postbiotic extract is also disclosed.Type: GrantFiled: September 29, 2020Date of Patent: January 3, 2023Assignee: CHAMBIO CO., LTD.Inventors: Meei-Yn Lin, Hung-Pin Chiu, Yi-Heng Chiu
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Patent number: 11517596Abstract: A method for alleviating arthritis includes administering to a subject in need thereof a postbiotic extract. The postbiotic extract is prepared by a process including the steps of providing a first material having a first isoelectric point ranging from pH 1 to pH 6 and a second material having a second isoelectric point ranging from pH 4 to pH 8, admixing the first material and a probiotic microorganism with water having a pH greater than the second isoelectric point, so as to forma mixture, adding the second material into the mixture and then adjusting a pH of the second material-added mixture to between the first and second isoelectric points so that a precipitate is formed, and subjecting the precipitate to a cell wall isolation treatment to obtain the postbiotic extract.Type: GrantFiled: September 29, 2020Date of Patent: December 6, 2022Assignee: CHAMBIOCO., LTD.Inventors: Meei-Yn Lin, Hung-Pin Chiu, Yi-Heng Chiu
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Patent number: 11458175Abstract: The present disclosure relates to a composition comprising a Lactobacillus plantarum CJLP475 strain deposited under Accession No. KCCM12287P; and a Lactobacillus plantarum CJLP243 strain deposited under Accession No. KCCM11045P, and use thereof.Type: GrantFiled: July 12, 2019Date of Patent: October 4, 2022Assignee: CJ CHEILJEDANG CORPORATIONInventors: Hee-Yeon Kim, Ho Jin Moon, Kyu Yeol Son, Kyung Min Lee, Yoon Tack Jang, Sung Hun Kim, Gi Duk Bae, Bong Joon Kim
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Patent number: 11390892Abstract: The present invention is in the field of a method of producing lactic acid in high yield in a sequencing batch reactor. Therein glucose may be used as feedstock for bacteria, which ferment the glucose into lactic acid. The reactor is operated under at least partly defined non-axenic conditions and in a cyclic mode.Type: GrantFiled: May 8, 2020Date of Patent: July 19, 2022Assignee: NATURE'S PRINCIPLES B.V.Inventors: Julius Laurens Rombouts, Marinus Cornelius Maria Van Loosdrecht, Robbert Kleerebezem, David Gregory Weissbrodt, Gerben Stouten, Maximilienne Toetie Allaart
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Patent number: 11390692Abstract: Compositions are disclosed herein comprising dextran that comprises (i) 87-93 wt % glucose linked at positions 1 and 6; (ii) 0.1-1.2 wt % glucose linked at positions 1 and 3; (iii) 0.1-0.7 wt % glucose linked at positions 1 and 4; (iv) 7.7-8.6 wt % glucose linked at positions 1, 3 and 6; and (v) about 0.4-1.7 wt % glucose linked at (a) positions 1, 2 and 6, or (b) positions 1, 4 and 6. Aqueous forms of this composition have enhanced viscosity profiles. Further disclosed are methods of using compositions comprising dextran, such as increasing the viscosity of an aqueous composition. Enzymatic reactions for producing dextran are also disclosed.Type: GrantFiled: August 24, 2018Date of Patent: July 19, 2022Assignee: NUTRITION & BIOSCIENCES USA 4, INC.Inventors: Rakesh Nambiar, Rong Guan, Qiong Cheng, Robert Dicosimo, Jayme L. Paullin, Yuanfeng Liang, Charles R. Powley, Yefim Brun
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Patent number: 11238261Abstract: An ultrasonic fingerprint recognition module is described that includes sensing units distributed in the form of array, where the sensing units include: a receiving electrode layer having a plurality of receiving electrodes distributed in the form of array; a piezoelectric material layer disposed on one side of the receiving electrode layer; an emission electrode layer disposed on a side of the piezoelectric material layer distal to the receiving electrode layer, and including a plurality of rows of emission electrodes; a selection circuit having an input terminal which is connected with an excitation signal and an output terminal which is connected with the emission electrode for selecting to transmit the excitation signal to the plurality of emission electrodes; and a pixel receiving circuit connected to the receiving electrode layer that receives a fingerprint signal.Type: GrantFiled: June 29, 2020Date of Patent: February 1, 2022Assignee: BOE TECHNOLOGY GROUP CO., LTD.Inventors: Xiufeng Li, Haisheng Wang, Xiaoliang Ding, Pengpeng Wang, Yuzhen Guo, Lijun Zhao, Chenyang Zhang, Yaqian Ji, Yanling Han, Peixiao Li
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Patent number: 11207358Abstract: The present invention relates to a composition comprising a given Lactobacillus rhamnosus strain and a given Lactobacillus paracasei strain wherein the ratio of the given Lactobacillus rhamnosus strain to the given Lactobacillus paracasei strain (LR?:LP?) is higher or equal to 8:1 and to methods thereof.Type: GrantFiled: December 16, 2016Date of Patent: December 28, 2021Assignee: COMPAGNIE GERVAIS DANONEInventors: Tamara Smokvina, Rebeca Martin Rosique, Philippe Langella
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Patent number: 11166991Abstract: The invention relates to a novel bacterial strain deposited with the CNCM under number 1-4969. This strain has properties that are useful in the treatment of respiratory disorders. The invention also relates to compositions and uses of said strain.Type: GrantFiled: January 27, 2017Date of Patent: November 9, 2021Assignee: Institut National De La Recherche AgronomiqueInventors: Muriel Thomas, Aude Remot-Brizion, Philippe Langella
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Patent number: 11066694Abstract: The present invention concerns compositions and processes that use affinity tags for isolating, and detecting or quantifying analytes, including nucleic acids, proteins and polypeptides. Compositions include nucleic acid compositions and protein compositions with affinity binding pairs, including metal binding peptides and immobilized metals, or peptide affinity groups.Type: GrantFiled: December 19, 2018Date of Patent: July 20, 2021Assignee: Enzo Biochem, Inc.Inventors: Elazar Rabbani, Jannis G. Stavrianopoulos, James J. Donegan, Wayne Patton, Juan Carcamo
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Patent number: 10835485Abstract: The present invention is concerned with microorganisms or fragments thereof as sensorically neutral oral care agents, particularly for prevention of dental calculus, as anti-caries agents and/or anti-oral malodor agents. The invention is furthermore concerned with compositions comprising microorganisms or fragments thereof for reducing mutans Streptococci. Such compositions can be used in oral care compositions, e.g. for caries prophylaxis, or for prophylaxis of dental calculus or oral malodor. They may also or instead be used for prevention or treatment of oral malodor. As the microorganisms and fragments thereof according to the present invention have a very low, unobtrusive smell and taste, they are particularly suited as sensorically neutral agents for preventment of dental calculus, caries, oral biofilm formation and/or for prevention or treatment of oral malodor.Type: GrantFiled: December 6, 2016Date of Patent: November 17, 2020Assignee: BASF SEInventor: Markus Pompejus
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Patent number: 10188684Abstract: The present invention provides a method for preventing or treating a functional gastrointestinal disorder in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. The present invention further provides a method for preventing or treating visceral hypersensitivity in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. Moreover, the present invention provides a method for preventing or treating functional abdominal pain, irritable bowel syndrome or constipation in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier.Type: GrantFiled: April 20, 2015Date of Patent: January 29, 2019Assignee: National Yang-Ming UniversityInventors: Ying-Chieh Tsai, Jian-Fu Liao, Chih-Chieh Hsu
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Patent number: 9854822Abstract: Microbial starter cultures. More specifically, a method for preparing a microbial starter culture wherein the microorganism is inoculated in a culture medium comprising at least one 5 yield enhancing agent selected from the group consisting of a purine base, a pyrimidine base, a nucleoside and a nucleotide. Such microbial starter cultures are useful in the manufacturing of food, feed and pharmaceutical products.Type: GrantFiled: January 5, 2006Date of Patent: January 2, 2018Assignee: CHR. HANSEN A/SInventors: Børge Windel Kringelum, Niels Martin Sørensen, Christel Garrigues, Martin B. Pedersen, Susanne Grøn
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Patent number: 9839656Abstract: A composition comprising specific Lactobacillus helveticus strains is provided for reducing the symptoms of allergies originating from food, respiratory or contact allergens. Preferably the composition reduces symptoms of allergies (secondary prevention) while also able to reduce sensitization (primary prevention).Type: GrantFiled: January 16, 2013Date of Patent: December 12, 2017Assignee: Nestec S.A.Inventors: Sebastien Holvoet, Annick Mercenier, Marietta Weiss, Adrian Walter Zuercher
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Patent number: 9771624Abstract: The multiple embodiments described herein comprise the genome of a probiotic Bifidobacterium longum bifidobacteria strain and genes encoded by the genome. Various novel Bifidobacterium longum are described.Type: GrantFiled: November 11, 2009Date of Patent: September 26, 2017Assignee: The Procter & Gamble CompanyInventors: Douwe Van Sinderen, Jun Xu, Wenzhu (Steven) Zhao, Raymond A. Grant, Song Yuli, Charles Bascom, Duane Larry Charbonneau, Liam O'Mahony
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Patent number: 9737577Abstract: An object of the present invention is to provide a useful composition that contains a highly safe lactic acid bacterium or a component derived from this lactic acid bacterium. The present invention relates to a composition comprising at least one lactic acid bacterium selected from the group consisting of Lactobacillus delbrueckii subsp. lactis strain KR-037 (NITE BP-395), Lactobacillus delbrueckii subsp. lactis strain KLAB-4 (NITE BP-394), and variants thereof, or comprising a component derived from the lactic acid bacterium. The composition of the present invention is useful as a preparation that has an excellent antiallergic function and also has at least one other function selected from an anti-autoimmune disease function, a diabetes-improving function, a neutral fat-lowering function, and so forth.Type: GrantFiled: March 10, 2015Date of Patent: August 22, 2017Assignee: KANEKA CORPORATIONInventors: Airo Tategaki, Toyoaki Watanabe, Kazuya Hamada
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Patent number: 9629883Abstract: The present invention discloses different specific bacterial strains isolated from individuals without caries which are characterized in that they present inhibitory activity against cariogenic organisms. The invention also discloses a process for isolating said strains, as well as bioactive peptides, such as anti-microbial peptides of human and bacterial origin, which also show anti-cariogenic activity. Moreover, the present invention also discloses pharmaceutical and/or probiotic/prebiotic compositions, functional foods, mouthwashes, toothpaste, chewing gum, etc., that comprise at least one of the strains and/or at least one of the bioactive peptides described in the invention, or a combination thereof, which are useful in the treatment and/or prevention of infectious diseases of the buccal cavity, preferably caries.Type: GrantFiled: August 31, 2011Date of Patent: April 25, 2017Assignee: CENTRO SUPERIOR DE INVESTIGACIÓN EN SALUD PÚBLICA (CSISP)Inventor: Alejandro Mira Obrador
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Patent number: 9185927Abstract: The present invention relates to a selected strain of Lactobacillus pentosus for use as a medication for the preventive or curative treatment of infections due to Gram-negative bacteria, preferably enterococci, coliforms and E. coli.Type: GrantFiled: May 27, 2010Date of Patent: November 17, 2015Assignee: Probiotical S.p.A.Inventors: Giovanni Mogna, Gian Paolo Strozzi, Luca Mogna
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Patent number: 9169499Abstract: An engineering method was developed to allow genetic modification and isolation of lactic acid bacteria cells that lack lactate dehydrogenase and acetolactate decarboxylase activities. In cells with these modifications and an isobutanol biosynthetic pathway, improved production of isobutanol was observed.Type: GrantFiled: September 29, 2010Date of Patent: October 27, 2015Assignee: BUTAMAX ADVANCED BIOFUELS LLCInventors: Brian James Paul, Wonchul Suh
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Patent number: 9101158Abstract: The present invention addresses the problem of providing a soybean-derived raw material-containing food or beverage that improves problems with flavor and physical properties, such as the grassy smell caused by soybean raw materials, and markedly improves product quality, in a soybean-derived raw material-containing food or beverage using conventional soybean raw materials such soymilk or tofu. Provided are a milk-substitute composition, and an egg-yolk substitute composition, etc., characterized by including a soybean emulsion composition having a protein content relative to dry material of at least 25 wt %, a fat content (as a chloroform/methanol mixed solvent extract) relative to the protein content of at least 100 wt %, and an LCI value of at least 55%. Also provided are a variety of soybean-derived raw material-containing food and beverages using these compositions.Type: GrantFiled: May 23, 2012Date of Patent: August 11, 2015Assignee: FUJI OIL COMPANY LIMITEDInventors: Masahiko Samoto, Jiro Kanamori, Norifumi Adachi, Chizuru Ueno, Eriko Harada, Mai Kanda, Takahiro Tsuruda, Ayako Ogama, Yuki Usui, Koichi Saito, Kohsuke Ito, Hideo Sugano, Masashi Asanoma, Mitsutaka Kohno, Masayuki Shibata, Yuusuke Shishido, Sayuri Kitagawa, Miyuki Kanaya, Shigeru Ashida, Takayasu Motoyama
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Patent number: 9101651Abstract: The present invention generally relates to the field of obesity. In particular the present invention relates to the use of probiotics to treat obesity. One embodiment of the present invention relates to the use of Lactobacillus rhamnosus CGMCC 1.3724 and/or Lactobacillus rhamnosus NCC 4007 for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity.Type: GrantFiled: April 10, 2013Date of Patent: August 11, 2015Assignee: Nestec S.A.Inventors: Christian Darimont, David Philippe, Catherine Mace, Fabrizio Arigoni
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Patent number: 9057112Abstract: The invention herein provides certain strains of lactic acid bacteria selected for their capability of promoting production of IL-10 and consequently proliferation of CD4+CD25+ TR cells, for prophylaxis and/or treatment of infant colic, a method of selecting such strains, and products containing such strains.Type: GrantFiled: October 29, 2007Date of Patent: June 16, 2015Assignee: BIOGAIA ABInventors: Eamonn Connolly, Bo Mollstam
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Patent number: 9040037Abstract: The present invention provides a triple vital bacteria composition, including: powder of Bifidobacterium longum, powder of Lactobacillus acidophilus, and powder of Streptococcus faecalis. The present invention further provides a method for preparing the above triple vital bacteria composition, as well as the protection agents, the fermenting culture medium and the seed culture medium used therein.Type: GrantFiled: February 3, 2008Date of Patent: May 26, 2015Assignee: Shanghai Sine Pharmaceutical Laboratories Co., Ltd.Inventors: Binhua Chen, Xuesong Wang, Liang Zhang
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Publication number: 20150139968Abstract: The present invention relates to a composition used for treating picornavirus infection comprising at least one of the following bacterial strains: Lactobacillus paracasei GMNL-33 with the deposition numbers of CCTCC M 206133, Lactobacillus reuteri GMNL-89 with the deposition numbers of CCTCC M 207154 and Lactobacillus casei GMNL-277 with the deposition numbers of CCTCC M 2013197, and a pharmaceutically acceptable vehicle. The Lactobacillus casei GMNL-277 of the invention is a novel Lactobacillus isolated strain. In addition, the present invention also features the novel use of the composition of the Lactobacillus strains for treating picornavirus infection, and the mechanism of which is inhibition of virus infection by binding of the probiotic bacteria to viruses.Type: ApplicationFiled: November 15, 2013Publication date: May 21, 2015Applicant: GENMONT BIOTECH INC.Inventors: Ya-Fang Wang, Jen-Ren Wang, Yi-Hsing Chen
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Publication number: 20150132270Abstract: The present invention relates to novel strains of Lactobacillus as well as preparations and compositions, such as fermentation broths, protective cultures, final food or feed product with Lactobacillus alone or in combination with bacteria of the genus Propionibacterium. The present invention further relates to methods for the controlling of growth of a contaminant, such as a bacteria, yeast or mould by using these novel strains of Lactobacillus.Type: ApplicationFiled: May 21, 2013Publication date: May 14, 2015Inventors: Connie Benfeldt, Heike Ursula Morgenstern
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Patent number: 9011838Abstract: Methods and compositions are hereby disclosed for reducing the numbers of E. coli O157:H7, Salmonella or other pathogens in an animal. The methods include administering to the animal a lactic acid producing bacterium at a relatively low dosage in combination with a lactate utilizing bacterium, followed by administration of the lactic acid producing bacterium at a relatively high dosage. The disclosed methods help achieve pre-harvest food safety and enhance feed performance while keeping the total cost relatively low. The preferred lactic acid producing bacterium is Lactobacillus acidophilus/animalis and the preferred lactate utilizing bacterium is Propionibacterium freudenreichii.Type: GrantFiled: April 20, 2010Date of Patent: April 21, 2015Assignee: Nutrition Physiology Company, LLCInventors: Douglas Ware, Peter Anderson
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Patent number: 9011877Abstract: TRFs useful for identifying strains of interest are provided. A method of identifying one or more strain that can be used as a direct-fed microbial is also provided. One or more strain identified by the method is additionally provided. A method is also provided for administering to an animal an effective amount of the one or more strain. Additionally provided is an isolated strain chosen from at least one of Lactobacillus acidophilus strain P1B c6 (NRRL B-50103), Lactobacillus salivarius strain o246e 33w (NRRL B-50102), Pediococcus acidilactici strain o246e 42 (NRRL B-50171), and Pediococcus acidilactici strain P1J e3 (NRRL B-50101). An isolated strain having all of the identifying characteristics of one of the strains listed above is also provided. One or more strain can be administered as a direct-fed microbial to an animal. Methods of preparing a direct-fed microbial are also provided.Type: GrantFiled: October 9, 2013Date of Patent: April 21, 2015Assignee: Dupont Nutrition Biosciences APSInventors: Mari Ellen Davis, Joshua M. Rehberger, Charles Maxwell, Thomas G. Rehberger, Mike King
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Patent number: 8986675Abstract: The present invention relates to the prevention and treatment of obesity and obesity related metabolic syndrome, particularly to the prevention and treatment of obesity by changing intestinal flora. The characteristics of intestinal bacteria are transformed by administration of a microorganism preparation which improves free fatty acid absorption by the bacteria, and free fatty acid absorption in the gastrointestinal tract is thereby decreased by introduction thereof. The present invention provides a method for preventing and treating obesity and obesity related metabolic syndrome, a pharmaceutical composition and diet supplement for prevention and treatment thereof, and modified probiotic strains usable for such purposes. The present invention provides a weight loss effect and shows that the absorption of fatty acids in the gastrointestinal tract is blocked by improving the characteristics of intestinal bacteria and transplanting them, thereby enabling the treatment of obesity.Type: GrantFiled: June 5, 2009Date of Patent: March 24, 2015Assignee: Jinis Biopharmaceuticals Co.Inventors: Hyeon Jin Kim, Seong Tshool Hong
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Publication number: 20150079057Abstract: The present invention is related to the field of bioprotection, in particular to the strain of Lactobacillus rhamnosus CHCC5366 with accession no. DSM23035. Furthermore, the present invention concerns an antifungal composition comprising the strain, an antifungal composition comprising the strain and at least one strain of Lactobacillus paracasei, food, feed and pharmaceutical products comprising such an antifungal composition, a method of manufacturing such food, feed and pharmaceutical products, a method for reducing the content of yeasts and molds of such food, feed and pharmaceutical products and uses of the antifungal composition.Type: ApplicationFiled: April 9, 2013Publication date: March 19, 2015Applicant: CHR. HANSEN A/SInventors: Tina Hornbaek, Maike Lisberg, Silja Kej Diemer
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Publication number: 20150079040Abstract: The invention provides probiotic bacteria and lysates thereof for use in methods of medical and cosmetic treatment. Use in the treatment of infections, including skin infections and methods involving regeneration or repair of the skin barrier are contemplated.Type: ApplicationFiled: March 15, 2013Publication date: March 19, 2015Inventors: Catherine O'Neill, Andrew McBain
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Publication number: 20150079232Abstract: The present invention relates to mutants of lactic acid bacteria which are resistant to the antibiotic ampicillin and which were found to give an increased texture when grown in milk while maintaining the other growth properties of the parent strain. The present invention, furthermore, relates to compositions comprising such mutants, and to dairy products fermented with the lactic acid bacteria resistant to ampicillin.Type: ApplicationFiled: April 23, 2013Publication date: March 19, 2015Applicant: Chr. Hansen A/SInventors: Eric Johnsen, Kim Ib Soerensen, Annette Kibenich
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Publication number: 20150079236Abstract: The present invention relates to food-grade bacteria strain being capable of removing mercury from an aqueous environment.Type: ApplicationFiled: April 5, 2013Publication date: March 19, 2015Inventors: Jeremy Burton, Marc Monaches, Gregor Reid, Tamara Smokvina, Johan Van Hylckama Vlieg
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Patent number: 8980611Abstract: Compositions and methods useful for reducing or eliminating the presence of pathogens in meat or meat products are disclosed. Administration of one or more lactic acid producing microorganisms to a live animal, to a carcass, to meat, to meat products, or in animal feed results in significant reductions in the amount of pathogens potentially harmful to humans when ingested. Synergistic effects can be achieved with the administration of multiple strains of microorganisms.Type: GrantFiled: July 25, 2013Date of Patent: March 17, 2015Assignee: Guardian Food Technologies, LLCInventors: Douglas R. Ware, Mindy M. Brashears
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Publication number: 20150072033Abstract: The present invention generally relates to the field of pro biotic micro-organisms, in particular to the field of non-replicating probiotic micro-organisms. Embodiments of the present invention relate to compositions comprising probiotic microorganisms that were rendered non-replicating by extrusion. Such compositions may be used to treat or prevent disorders that are related to a compromised immune system.Type: ApplicationFiled: November 14, 2014Publication date: March 12, 2015Inventors: Annick Mercenier, Antoine Wermeille, Audrey Demont, Guenolee Prioult
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Patent number: RE46718Abstract: The invention refers to a composition comprising one or more tannase-producing strains of Lactobacillus having the ability to adhere to the human intestinal mucosa in combination with tannin. New tannase-producing strains of Lactobacillus plantarum are a.Type: GrantFiled: June 5, 2013Date of Patent: February 20, 2018Assignee: Probi ABInventors: Goran Molin, Siv Ahrné, Bengt Jeppsson
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Patent number: RE48652Abstract: The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well. Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body.Type: GrantFiled: May 14, 2018Date of Patent: July 20, 2021Assignee: BIONEER CORPORATIONInventors: Ji Hee Kang, Byeung Il You, Sung Il Yun, Han Oh Park