Using Fungi Patents (Class 435/911)
  • Patent number: 8859228
    Abstract: The invention relates to a novel method for the production of ?-carotene from submerged cultures of mucoral fungi such as Blakeslea, Choanephora or Phycomyces by adding lectin to the culture medium and performing pH control once fermentation has started. The method involves ?-carotene recovery stage that makes it possible to simplify the process, optimize yields and increase purification of the product.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: October 14, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Javier Costa Perez, Antonio Estrella Castro, Ana Teresa Marcos Rodriguez, J. Emiliano Gonzalez De Prado, Enrique R. Peiro Cezon, Alfonso Collados De La Vieja, Manuel Esteban Morales
  • Patent number: 8765447
    Abstract: A fungal strain Beauveria species bearing accession number MTCC 5184 is disclosed. The process for the preparation of an enzyme mix including at least one enzyme selected from, but not limited to protease, carbohydrase, and lipase from the disclosed Beauveria species and uses of the enzyme mix in various areas also disclosed.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: July 1, 2014
    Assignee: Council of Scientific and Industrial Research
    Inventors: Seeta Laxman Ryali, Shiv Shankar, Snehal Vijay More, Harish Bansilal Khandelwal, Chandra Babu Kannan Narasimhan, Saravanan Palanivel, Padmanabhan Balaram
  • Patent number: 8703456
    Abstract: The present invention discloses a method for manufacturing red mold dioscorea, and the method comprises the following steps: washing and cutting a fresh dioscorea into pieces with a specific dimension; drying the pieces of the fresh dioscorea for making the dried dioscorea contain a specific water content and a specific sulfur content; adding some water with an appropriate ratio to fresh dioscorea or dried dioscorea; sterilizing the dioscorea; after the dioscorea being cooled down, inoculating the dioscorea with Monascus species; cultivating the dioscorea with an appropriate temperature, an appropriate humidity and an appropriate shacking frequency for an appropriate time period; and drying the cultivated red mold dioscorea with an appropriate water content.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: April 22, 2014
    Assignee: Sunway Biotech Co., Ltd.
    Inventors: Tzu-Ming Pan, Chun-Lin Lee
  • Patent number: 8697424
    Abstract: The present invention discloses a method for manufacturing red mold dioscorea, and the method comprises the following steps: washing and cutting a fresh dioscorea into pieces with a specific dimension; drying the pieces of the fresh dioscorea for making the dried dioscorea contain a specific water content and a specific sulfur content; adding some water with an appropriate ratio to fresh dioscorea or dried dioscorea; sterilizing the dioscorea; after the dioscorea being cooled down, inoculating the dioscorea with Monascus species; cultivating the dioscorea with an appropriate temperature, an appropriate humidity and an appropriate shacking frequency for an appropriate time period; and drying the cultivated red mold dioscorea with an appropriate water content.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: April 15, 2014
    Assignee: Sunway Biotech Co., Ltd.
    Inventors: Tzu-Ming Pan, Chun-Lin Lee
  • Patent number: 8563236
    Abstract: The invention provides novel mutations, mutation combinations or mutational profiles of HIV-1 reverse transcriptase and/or protease genes correlated with phenotypic resistance to HIV drugs. More particularly, the present invention relates to the use of genotypic characterization of a target population of HIV and the subsequent correlation of this information to phenotypic interpretation in order to correlate virus mutational profiles with drug resistance. The invention also relates to methods of utilizing the mutational profiles of the invention in databases, drug development, i.e., drug design, and drug modification, therapy and treatment design, clinical management and diagnostic analysis.
    Type: Grant
    Filed: January 13, 2009
    Date of Patent: October 22, 2013
    Assignee: Virco, N.V.
    Inventors: Kurt Hertogs, Brendan Larder, Rudi Pauwels
  • Patent number: 8465963
    Abstract: Described is the method and use of AR584 endophyte (AGAL deposit no. NM98/04676 dated 12 May 1998) or variations in endophyte as exemplified by AR584, to produce a grass cultivar and AR584 combination wherein the plant or a part thereof produced by the combination retains viable AR584 endophyte after treatment with fungicide and/or after being subjected to elevated temperature or humidity.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: June 18, 2013
    Assignee: Grasslanz Technology Ltd.
    Inventors: Maurice Philip Rolston, Wayne Roydon Simpson
  • Patent number: 8288133
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: October 16, 2012
    Assignee: DSM IP Assets B.V.
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8288134
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: October 16, 2012
    Assignee: DSM IP Assets B.V.
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8216812
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: July 10, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8206956
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: June 26, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8187846
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: May 29, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8187845
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: May 29, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8183031
    Abstract: It is intended to utilize ?-glucan produced by a bacterium belonging to Aureobasidium sp. From a bacterium belonging to Aureobasidium sp., a mutant with little pigment accumulation is constructed by a mutagenesis means of, for example, irradiating with ultraviolet light or treating with a mutagen. A culture obtained by culturing this mutant in a liquid culture medium is usable as a composition with a large ?-glucan content without showing any intense dark green color caused by the accumulation of melanin-like pigments. This composition may be taken as such as a functional food having the physiologically active functions of the ?-glucan-containing composition. Alternatively, it may be added to foods, drinks. food additives, cosmetics and so on.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: May 22, 2012
    Assignee: Aureo Co., Ltd.
    Inventors: Naoyuki Moriya, Yukiko Moriya, Koji Kubota
  • Patent number: 8133706
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: March 13, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8124384
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: February 28, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 8124385
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: February 28, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, John M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 7977550
    Abstract: Seeds of plants stably infected with isolated endophytes selected from the group consisting of ATCC Deposit No. PTA-6499, PTA-8827, PTA-8828, and PTA-8829 are disclosed.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: July 12, 2011
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Charles P. West, Edgar L. Piper
  • Patent number: 7976857
    Abstract: An endophyte or endophyte culture of N. lolii species is described that, in combination with a host grass does not cause typical symptoms of ryegrass toxicosis in grazing animals and also contains levels of compounds from the class of janthitrems epoxides to individually or in combination protect the host grass from pests or abiotic stresses or both. Uses and methods are also described to produce and characterise the combination as well as alternative uses for compounds from the class of janthitrem epoxide compounds.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: July 12, 2011
    Assignee: Grasslanz Technology Limited
    Inventors: Brian Anthony Tapper, Bruce Matheson Cooper, Herrick Sydney Easton, Lester Ronald Fletcher, David Edward Hume, Geoffrey Alexander Lane, Garrick Cecil Morland Latch, Christopher Gerald Lee Pennell, Alison Jean Popay, Michael John Christensen
  • Patent number: 7919102
    Abstract: Basidiomycetes which is a novel mushroom having an excellent immunopotentiating action, etc., a Basidiomycetes extract composition, and health foods and immunopotentiators using the Basidiomycetes extract composition are provided. Basidiomycetes has no basidium forming potential. In particular, Basidiomycetes is Basidiomycetes-X FERM BP-10011. A Basidiomycetes extract composition is extracted from them with an extraction solvent including at least one solvent selected from water and a hydrophilic solvent.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: April 5, 2011
    Assignee: Mycology Techno. Corp.
    Inventor: Tetsuo Watanabe
  • Patent number: 7897387
    Abstract: A reporter system reflecting the transport process that transports GPI-anchored proteins to the cell wall was constructed and compounds inhibiting this process were discovered. Further, genes conferring resistance to the above compounds were identified and methods of screening for compounds that inhibit the activity of the proteins encoded by these genes were developed. Therefore, through the novel compounds, the present invention showed that antifungal agents having a novel mechanism, i.e. inhibiting the process that transports GPI-anchored proteins to the cell wall, could be achieved.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: March 1, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Kappei Tsukahara, Katsura Hata, Koji Sagane, Kazutaka Nakamoto, Mamiko Tsuchiya, Naoaki Watanabe, Fuminori Ohba, Itaru Tsukada, Norihiro Ueda, Keigo Tanaka, Junko Kai
  • Patent number: 7795002
    Abstract: The present invention provides a novel lower eukaryotic host cell producing human-like glycoproteins characterized as having a terminal ?-galactose residue and essentially lacking fucose and sialic acid residues. The present invention also provides a method for catalyzing the transfer of a galactose residue from UDP-galactose onto an acceptor substrate in a recombinant lower eukaryotic host cell, which can be used as a therapeutic glycoprotein.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: September 14, 2010
    Assignee: Glycofi, Inc.
    Inventors: Robert Davidson, Tillman Ulf Gerngross, Stefan Wildt, Byung-Kwon Choi, Juergen Hermann Nett, Piotr Bobrowicz, Stephen Robin Hamilton
  • Patent number: 7732170
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: June 8, 2010
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, Jon M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 7731984
    Abstract: The present invention describes substantially pure cultures of three new species of fungi, Meira geulakonigae (CBS 110052), Meira argovae (CBS 110053) and Acaromyces ingoldii (CBS 110050) (all nom. prov.), wherein said cultures are biologically pure. The conditioned medium for all three new fungi species is also described, as well as their biologically active products. The biological product of the three new fungi species and their conditioned medium has miticidal and fungicidal activities. Thus, a composition for the control of mites and/or phytopathogenic fungi comprising a biocontrol agent derived from any one of the three new fungi species is also described, optionally comprising an agriculturally compatible carrier. Finally, the present invention describes a method for producing a fungicide and/or a miticide, wherein the active ingredient of said fungicide/miticide is any one of M. geulakonigae, M. argovae, or A.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: June 8, 2010
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem
    Inventors: Abraham Sztejnberg, Uri Gerson, Aviva Gafni
  • Patent number: 7718416
    Abstract: Methods for stimulating in-vitro paecilomyces hepiali or hirsutella sinensis growth, and nutritional supplement formulations containing such fungal strains are disclosed and described. In some embodiments, such a method may include providing a an effective amount of a p. hepiali fungus strain for use as a stimulating agent on a culture medium for which h. sinensis is grown and regulating the temperature to induce and maintain the growth of the h. sinensis fungus. Alternatively, a p. hepiali fungus may be grown in a similar manner using h. sinensis as the stimulating agent. In some aspects, the growth of one fungus may be sequentially switched with the other in order to improve fungi potency.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: May 18, 2010
    Assignee: NSE Products, Inc.
    Inventor: Jai-Shi Zhu
  • Patent number: 7687246
    Abstract: The present invention relates to a biological process for producing carotenoids utilizing a microorganism which is capable of producing carotenoids and belonging to the genus Xanthophyllomyces (Phaffia) in the presence of an inhibitor for biosynthesis of sterols from farnesyl pyrophosphate.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: March 30, 2010
    Assignee: DSM IP Assets B. V.
    Inventors: Tatsuo Hoshino, Setsuko Masuda, Yutaka Setoguchi
  • Patent number: 7625728
    Abstract: Effective processes are provided for the production of xylitol and ethanol and other products from solutions derived from lignocellulose-containing material in biomass. The solutions can be hydrolyzed or partially hydrolyzed before being fermented with microbes. The fermented solution can be distilled and can be subsequently separated, such as, by chromatographic separation, membrane separation, etc. The recovered xylitol solution can be crystallized to provide pure xylitol crystals.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: December 1, 2009
    Assignee: Danisco Sweeteners Oy
    Inventors: Olli-Pekka Eroma, Heikki Heikkila, Heikki Ojamo, Päivi Sarmala, Göran Hyöky, Leena Rahkila, Marja-Leena Sarkki, Tapio Viljava
  • Patent number: 7585651
    Abstract: A process for producing lipids containing arachidonic acid comprising culturing a microorganism in which ?3 desaturase activity has been decreased or is lacking at a temperature lower than the optimum growth temperature from the start of culturing or after culturing at the optimum growth temperature, said microorganism being obtained by the mutation treatment of a microorganism capable of producing arachidonic acid and belonging to the genus Mortierella and the like; and then recovering lipids containing arachidonic acid from the culture.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: September 8, 2009
    Assignee: Suntory Holdings Limited
    Inventors: Kengo Akimoto, Kenichi Higashiyama, Sakayu Shimizu
  • Patent number: 7579174
    Abstract: The present invention provides a process for growing eukaryotic microorganisms which are capable of producing lipids, in particular lipids containing polyenoic fatty acids. The present invention also provides a process for producing eukaryotic microbial lipids.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: August 25, 2009
    Assignee: Martek Biosciences Corporation
    Inventors: Richard B. Bailey, Don DiMasi, Jon M. Hansen, Peter J. Mirrasoul, Craig M. Ruecker, George T. Veeder, III, Tatsuo Kaneko, William R. Barclay
  • Patent number: 7517682
    Abstract: Basidiomycetes which is a novel mushroom having an excellent immunopotentiating action, etc., a Basidiomycetes extract composition, and health foods and immunopotentiators using the Basidiomycetes extract composition are provided. Basidiomycetes has no basidium forming potential. In particular, Basidiomycetes is Basidiomycetes-X FERM BP-10011. A Basidiomycetes extract composition is extracted from them with an extraction solvent including at least one solvent selected from water and a hydrophilic solvent.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: April 14, 2009
    Assignee: Mycology Techno.Corp.
    Inventor: Tetsuo Watanabe
  • Patent number: 7494768
    Abstract: The invention provides novel mutations, mutation combinations or mutational profiles of HIV-1 reverse transcriptase and/or protease genes correlated with phenotypic resistance to HIV drugs. More particularly, the present invention relates to the use of genotypic characterization of a target population of HIV and the subsequent correlation of this information to phenotypic interpretation in order to correlate virus mutational profiles with drug resistance. The invention also relates to methods of utilizing the mutational profiles of the invention in databases, drug development, i.e., drug design, and drug modification, therapy and treatment design, clinical management and diagnostic analysis.
    Type: Grant
    Filed: May 30, 2000
    Date of Patent: February 24, 2009
    Assignee: Tibotec-Virco Virology BVBA
    Inventors: Kurt Hertogs, Brendan Larder, Rudi Pauwels
  • Patent number: 7465855
    Abstract: A grass with improved environmental stress tolerance and low animal toxicity is disclosed where the grass is infected with an isolated endophyte selected from the groups consisting of USDA-PI no. 269850, Ijoukak, Morocco 92060, Boumalne-de-Dades, Morocco KBG 5921, USDA-PI no. 516560, Oujda, Morocco KBG 5892, and mixtures and combinations thereof. A method for stably infecting the grasses is also disclosed.
    Type: Grant
    Filed: February 28, 2005
    Date of Patent: December 16, 2008
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Charles P. West, Edgar L. Piper
  • Patent number: 7413881
    Abstract: A highly deacetylated chitosan obtained from microbial biomass, a method of obtaining chitosan from microbial biomass, and biomass for making chitosan are disclosed. The method includes providing chitin-containing biomass; reacting the chitin-containing biomass in a caustic solution of greater than 25 percent alkali at a reaction temperature greater than 95° C. for a reaction period of at least 10 hours to convert the chitin in the biomass to chitosan; and separating the chitosan from the caustic solution.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: August 19, 2008
    Assignee: Cargill, Incorporated
    Inventors: Weiyu Fan, John A. Bohlmann, James R. Trinkle, James Donald Steinke, Ki-Oh Hwang, Joseph P. Henning
  • Publication number: 20080110826
    Abstract: Use of a fungal biomass for treating industrial wastewaters containing at least one dye and related method, wherein: i. the fungal biomass contains at least the fungal species Rhizomucor pusillus (Lindt) Schipper; ii. the fungal biomass absorbs the at least one dye, so as to obtain wastewater that is basically free of the at least one dye.
    Type: Application
    Filed: November 8, 2007
    Publication date: May 15, 2008
    Applicants: MARCOPOLO ENGINEERING SPA, UNIVERSITA DEGLI STUDI DI TORINO
    Inventors: Valeria Paola Prigione, Giovanna Cristina Varese, Leonardo Casieri, Samuele Voyron, Antonio Bertolotto, Valeria Filipello Marchisio
  • Patent number: 7267975
    Abstract: The present invention relates to the discovery of a novel endophytic fungus, Muscodor vitigenus, from the liana, Paullinia paullinioides. This fungus produces naphthalene under certain cultural conditions that has chromatographic and mass spectral properties that are identical to authentic naphthalene. In a preferred embodiment, the naphthalene in the gas phase of M. vitigenus is useful in the repellency of unwanted insect pests. The unique biological activity of the novel endophyte suggests a wide range of potential practical applications, particularly in the area of insect repellents, insecticides, antimicrobials, anthelmintics and vermicides.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: September 11, 2007
    Assignee: Montana State University
    Inventors: Gary Strobel, Bryn Daisy
  • Patent number: 7226770
    Abstract: The properties of a fungal lipolytic enzyme can be altered by substituting amino acid residues corresponding to certain specified amino acid residues in the T. lanuginosus lipase. The altered property may be, e.g., an increased thermostability, an altered pH dependence, or an altered substrate specificity.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: June 5, 2007
    Assignee: Novozymes A/s
    Inventor: Erwin Ludo Roggen
  • Patent number: 7157090
    Abstract: The present invention relates to the establishment of a cultivation condition that is suitable for the large-scale production of pharmacologically active filtrates from a culture of A. camphorata, in particular, by optimizing the agitation rate and/or pH value during the cultivation. The present invention also relates to a process for obtaining pharmacologically active compositions from a culture of A. camphorata through a series of fractionation. This invention is further directed to the uses of the above compositions in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: October 30, 2003
    Date of Patent: January 2, 2007
    Assignee: Council of Agriculture, Executive Yuan
    Inventors: Mei-Chiao Wu, Shie-Jea Lin, Bor-Cheh Wang
  • Patent number: 7118906
    Abstract: The present invention particularly relates to a process of removal of polycyclic aromatic hydrocarbons phenanthrene and chrysene from wastewater and other contaminated sites by using a white-rot fungus Flavodon flavus (K 1) Ryv., which has been deposited at Agricultural Research Service Culture Collection (NRRL), 1815 North University Street, Peoria, Ill. 61604, USA bearing accession number NRRL 30302 on Mar. 10, 2000.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: October 10, 2006
    Assignee: Council of Scientific & Industrial Research
    Inventors: Chandralata Raghukumar, Mysore Srinivasa-Murthy Shailaja, Shilpa Kamat
  • Patent number: 7109005
    Abstract: Effective processes are provided for the production of xylitol and ethanol and other products from solutions derived from lignocellulose-containing material in biomass. The solutions can be hydrolyzed or partially hydrolyzed before being fermented with microbes. The fermented solution can be distilled and can be subsequently separated, such as, by chromatographic separation, membrane separation, etc. The recovered xylitol solution can be crystallized to provide pure xylitol crystals.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: September 19, 2006
    Assignee: Danisco Sweeteners Oy
    Inventors: Olli-Pekka Eroma, Heikki Heikkila, Heikki Ojamo, Päivi Sarmala, Göran Hyöky, Leena Rahkila, Marja-Leena Sarkki, Tapio Viljava
  • Patent number: 7094586
    Abstract: The present invention relates to transglutaminases and transglutaminase preparations obtained from lower fungi belonging to the class Oomycetes and unprecedented high-level expression is achievable by growing these coenocytium forming organisms, especially the strains Pythium sp., Pythium irregulare, Pythium dissotocum, Pythium periilum (or P. periplocum), Pythium torulosum, Pythium ultimum, Pythium aphanidermatum, Phytophthora cactorum, Phytophthora palmivora, Phytophthora porri, Phytophthora infestans, Phytophthora megasperma, Phytophthora cinnamomi and Phytophthora cryptogea; and a recombinant transglutaminase has been cloned and expressed, the enzyme and enzyme preparations being useful for cross-linking proteins, e.g. in flour, baked products, meat products, fish products, cosmetics, cheese, milk products, gelled food products and leather finishing, or as a glutaminase, e.g. in bread and other baked glutein-containing food products.
    Type: Grant
    Filed: June 7, 2002
    Date of Patent: August 22, 2006
    Assignee: Novozymes A/S
    Inventors: Lisbeth Bech, Grethe Rasmussen, Torben Halkier, Mariko Okada, Lene Nonboe Andersen, Markus Sakari Kauppinen, Thomas Sandal
  • Patent number: 7090857
    Abstract: The present invention relates to antigenic preparations comprising polysaccharides and/or glycopeptides preparable from keratinophilic fungi as well as yeasts, process for the preparation of these antigenic preparations, their use as pharmaceutical substances as well as their use as vaccines, including but not limited to, the prophylaxis and treatment of allergy, as well as for modulating the immune response.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: August 15, 2006
    Assignee: Boehringer Ingelheim Vetmedica GmbH
    Inventors: Dieter Farnow, Joachim Karle, Igor D. Poliakov, Ludmilla G. Ivanova
  • Patent number: 7087232
    Abstract: The present invention relates to the establishment of a cultivation condition that is suitable for the large-scale production of pharmacologically active filtrates from a culture of A. camphorata, in particular, by optimizing the agitation rate and/or pH value during the cultivation. The present invention also relates to a process for obtaining pharmacologically active compositions from a culture of A. camphorata through a series of fractionation. This invention is further directed to the uses of the above compositions in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: October 30, 2003
    Date of Patent: August 8, 2006
    Assignee: Council of Agriculture, Executive Yuan
    Inventors: Mei-Chiao Wu, Ren-Chang Huang, Shie-Jea Lin, Bor-Cheh Wang
  • Patent number: 7067303
    Abstract: Agricultural biomass hydrolysate is detoxified by culturing in the presence of the fungus Coniochaeta ligniaria (teleomorph) or its Lecythophora (anamorph) state. This organism is capable of significantly depleting the toxicant levels of furans, particularly furfural and 5-hydroxymethylfurfural. A new strain of the fungus has been isolated and deposited in the Agricultural Research Culture Collection (NRRL) in Peoria, Ill., as Accession No. NRRL 30616. The detoxified agricultural biomass hydrolysate is useful as a substrate for industrial fermentation processes, especially in saccharification treatments for bioethanol production.
    Type: Grant
    Filed: January 24, 2003
    Date of Patent: June 27, 2006
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Nancy N. Nichols, Maria J. Lopez, Bruce S. Dien, Rodney J. Bothast
  • Patent number: 7067304
    Abstract: The invention relates to Monascus purpureus mutants, which are useful in the preparation of fermentation products having blood pressure lowering activity with a very low amount of citrinin. The invention also provides a process for preparing the fermentation products having blood pressure lowering activity using the Monascus purpureus mutants, and the use of the fermentation products in lowering blood pressure.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: June 27, 2006
    Assignee: Food Industry Research and Development Institute
    Inventors: Yen-Lin Chen, Ing-Er Hwang, Ming-Chin Lin, Chien-Cho Chen, Gwo-Fung Yuan
  • Patent number: 7060286
    Abstract: The present invention provides an external preparation for skin which contains, as a major ingredient, oleaginous substances extracted from sporoderm-broken spores from Ganoderma lucidum. The spores are preferably being treated with germination activation. The oleaginous substances are preferred to be extracted by a supercritical fluid-carbon dioxide (SCF-CO2) method. The oleaginous substances prepared by SCF-CO2 is transparent and odorless. They also demonstrates effects on skin smoothening, wrinkles reduction, aging defiance, inflammation lessening, pigmentation lightening, and irritation alleviation. The external preparation can be a cosmetic or a therapeutic composition.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: June 13, 2006
    Inventors: Chee-Keung Chung, Siu-Kan Tong
  • Patent number: 7037711
    Abstract: The present invention relates to the establishment of a cultivation condition that is suitable for the large-scale production of pharmacologically active filtrates from a culture of A. camphorata, in particular, by optimizing the agitation rate and/or pH value during the cultivation. The present invention also relates to a process for obtaining pharmacologically active compositions from a culture of A. camphorata through a series of fractionation. This invention is further directed to the uses of the above compositions in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: October 30, 2003
    Date of Patent: May 2, 2006
    Assignee: Council of Agriculture
    Inventors: Mei-Chiao Wu, Ren-Chang Huang, Shie-Jea Lin, Bor-Cheh Wang
  • Patent number: 7033586
    Abstract: The present invention provides a Paecilomyces tenuipes T1 FERM BP-7861, insecticidal compositions, methods and uses. The insecticidal compositions comprise an insecticidally effective amount of Paecilomyces tenuipes T1 FERM BP-7861. The methods comprise applying Paecilomyces tenuipes T1 FERM BP-7861 to at least one location selected from a pest, a habitat of the pest and a plant. The uses are uses of Paecilomyces tenuipes T1 FERM BP-7861 for controlling a pest.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: April 25, 2006
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Susumu Shimizu, Shinji Isayama, Eiji Nitta
  • Patent number: 7022512
    Abstract: Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodiment of the present invention, the process produces microflora having a cell aggregate size useful for the production of food products for use in aquaculture. Further disclosed is a food product which includes Thraustochytrium, Schizochytrium, and mixtures thereof, and a component selected from flaxseed, rapeseed, soybean and avocado meal. Such a food product includes a balance of long chain and short chain omega-3 highly unsaturated fatty acids.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: April 4, 2006
    Assignee: Martek Biosciences Corporation
    Inventor: William R. Barclay
  • Patent number: 7011962
    Abstract: Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodiment of the present invention, the process produces microflora having a cell aggregate size useful for the production of food products for use in aquaculture. Further disclosed is a food product which includes Thraustochytrium, Schizochytrium, and mixtures thereof, and a component selected from flaxseed, rapeseed, soybean and avocado meal. Such a food product includes a balance of long chain and short chain omega-3 highly unsaturated fatty acids. In an embodiment, lipids are produced by growing microorganisms of the order Thraustochytriales in a medium and extracting the lipids.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: March 14, 2006
    Assignee: Martek Biosciences Corporation
    Inventor: William R. Barclay
  • Patent number: 7005280
    Abstract: Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride containing sodium salts, in particular sodium sulfate. In a preferred embodiment of the present invention, the process produces microflora having a cell aggregate size useful for the production of food products for use in aquaculture. Further disclosed is a food product which includes Thraustochytrium, Schizochytrium, and mixtures thereof, and a component selected from flaxseed, rapeseed, soybean and avocado meal. Such a food product includes a balance of long chain and short chain omega-3 highly unsaturated fatty acids. In an embodiment, lipids are produced by growing microorganisms of the order Thraustochytriales in a medium and extracting the lipids.
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: February 28, 2006
    Assignee: Martek Biosciences Corporation
    Inventor: William R. Barclay
  • Patent number: 6994849
    Abstract: A biologically pure culture of a yeast of the species Metschnikowia fructicola. The yeast is identified as NRRL Y-30752 and is capable of inhibiting growth of a deleterious micro-organism on a portion of a plant to which a biologically effective amount of a culture of the yeast is applied. Further disclosed is a composition for use in protection of agricultural produce including a biologically effective amount of Metschnikowia fructicola and a carrier. Further disclosed is an article of manufacture including packaging material and the disclosed composition which is identified for use in protection of agricultural produce from a deleterious micro-organism. Further disclosed is a method of inhibiting growth of a deleterious micro-organism on a portion of a plant including applying at least one time an agriculturally effective amount of yeast of the genus Metschnikowia to the portion of a plant.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: February 7, 2006
    Assignee: State of Israel, Ministry of Agriculture, Agricultural Research Organization
    Inventor: Samir Droby