Hetero-n Patents (Class 436/96)
  • Patent number: 4590166
    Abstract: This invention relates to a novel method for separating and measuring the amount of polar compounds, such as pyridostigmine, acetylcholine, neostigmine, and edrophonium, and their metabolites in aqueous solutions. The method is used to determine the urinary excretion and plasma levels of polar compounds administered to animals.
    Type: Grant
    Filed: March 11, 1983
    Date of Patent: May 20, 1986
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Robert I. Ellin, Peter Zvirblis
  • Patent number: 4563428
    Abstract: Boar taint in individual animal bodies, preferably carcasses or parts thereof, is detected by preparing an extract of a meat and/or fat sample from the body or part thereof, reacting said extract with a color reagent, for which the color intensity developed at certain wavelengths exhibit a statistical relationship with boar taint, determining the transmittance or absorbance of the reacted extract at one or more such wavelengths, and inserting the recorded values in the said statistical relationship. A high correlation has been found to exist between color reaction and boar taint evaluation so that the transmittance or absorbance at wave lengths characteristic of the color reaction gives a quantitative measure of boar taint intensity. This has made it possible to determine threshold values which objectively define organoleptic inacceptable taint levels.
    Type: Grant
    Filed: May 6, 1983
    Date of Patent: January 7, 1986
    Assignee: Slagteriernes Forskningsinstitut
    Inventor: Anna B. Mortensen
  • Patent number: 4513087
    Abstract: A device for detecting small amounts of a chemical such as ammonia, and other ammonia-like molecules such as hydrazine or pyridine, in air and in other gases is disclosed. A capillary tube serves as a multiple total reflective medium for an optical beam from a light-emitting diode. The outer surface of the capillary tube is coated with a dye which, when exposed to the chemical, changes color so that the multiply reflected light is modified. The resultant change in the output light intensity from the capillary tube is photodetected and recorded to sense the presence of the chemical. When the chemical is removed, the dye returns to its original color so that the device can be reused.
    Type: Grant
    Filed: January 31, 1983
    Date of Patent: April 23, 1985
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: John F. Giuliani, Henry Wohltjen
  • Patent number: 4460695
    Abstract: A method for the separation of theophylline and caffeine contained in body fluids is provided. A macroreticular styrene-divinylbenzene copolymer resin activated by a protic solvent is utilized. The body fluid is eluted with water in an isocratic manner to afford a theophylline sample uncontaminated with caffeine. Such samples are useful in immunoassay procedures for the measurement of theophylline.
    Type: Grant
    Filed: December 24, 1981
    Date of Patent: July 17, 1984
    Assignee: E. I. DuPont de Nemours and Company
    Inventors: Johanne C. Dickinson, William A. Frey
  • Patent number: 4419452
    Abstract: A method for detecting fluorescent materials in liquid chromatography. Fluorescent materials are excited by chemical reaction with chemical reagents to yield light (chemiluminescence) and detected at high sensitivity. The detection apparatus is composed of a mixer for mixing a solution containing separated fluorescent materials and solutions of chemical reagents to afford chemiluminescence, a flow cell and a light receptive detection means for detecting the light thus produced.
    Type: Grant
    Filed: August 12, 1981
    Date of Patent: December 6, 1983
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Kazuhiro Imai, Zenzo Tamura, Shin-ichiro Kobayashi
  • Patent number: 4405718
    Abstract: A urobilinogen control standard composition, control standard device and a method for preparing such composition are disclosed. The composition comprises a substituted indole:nonionic detergent solution which is reactive with p-diethylaminobenzaldehyde and hydrochloric acid. The composition is produced by dissolving the substituted indole in a selected nonionic detergent and diluting the solution to a predetermined level. The device is a carrier matrix impregnated with a solution of a substituted indole and a nonionic detergent.
    Type: Grant
    Filed: July 20, 1981
    Date of Patent: September 20, 1983
    Assignee: Miles Laboratories, Inc.
    Inventors: Myron C. Rapkin, David L. Tabb
  • Patent number: 4384206
    Abstract: Boar taint in individual carcasses of uncastrated boars or parts thereof is determined in a fast and simple manner by determining IR-spectrophotometrical transmission data for the individual carcass or part or preferably on a sample from the carcass or part, and comparing the spectral data registered with corresponding data having a statistical relationship to boar taint. A suitable determination is determination of the ratio between the absorptions at two different wave lengths in the range of 1275-1325 cm.sup.-1 in the IR spectrum of the fat sample. A still higher correlation between the particular spectral data and the organoleptic data is obtained when one or more further parameters with statistical correlation to the odor image is/are included, e.g., the concentration of unsaturated fatty acids in the fat of the boar carcass.
    Type: Grant
    Filed: January 13, 1981
    Date of Patent: May 17, 1983
    Assignee: Slagteriernes Forskningsinstitut
    Inventor: Ole-Christian Bjarno