Abstract: A cleaning solution for cleaning a contact lens, which includes at least one first component each consisting of a tertiary amine oxide which is represented by the formula given in the specification and at least one second component each consisting of an anionic surface active agent in the form of a triethanolamine salt, a total content of the at least one first component and the at least one second component being within a range of 0.1-20% by weight, a ratio of a total content of the at least one first component to a total content of the at least one second component being within a range from 1/4 to 30/1.

Abstract: Compositions and methods useful for disinfecting a contact lens are disclosed. The present methods comprise contacting a contact lens with a liquid medium containing an effective amount of an oxidative disinfectant component at conditions to effectively disinfect the contact lens. The contacting occurs in the presence of a color indicator component which is soluble in the liquid medium and is adapted to provide a color indication of the presence of the oxidative disinfectant component in the liquid medium. The color indicator component comprises an effective amount of a transition metal component which is redox active, has an oxidized state of a first color and a reduced state of a different second color and a polyanionic component in an amount effective to inhibit the staining of the contact lens by the transition metal component.

Abstract: A method of simultaneously cleaning and disinfecting a contact lens is disclosed, which method comprises the steps of: (a) preparing a cleaning solution for the contact lens comprising an effective amount of a proteolytic enzyme, 15-60 w/v % (percent by weight/volume) of propylene glycol, 10-60 w/v % of glycerine, and water, a total content of the propylene glycol and glycerine being in a range of 30-80 w/v %; (b) diluting the cleaning solution with a disinfecting or storing liquid for the contact lens which contains an ionic antimicrobial agent, so as to provide a dilution; and (c) immersing the contact lens in the dilution.

Abstract: It is an object of the present invention to provide a cleaning and disinfecting solution for a contact lens to be cleaned and disinfected simultaneously in a simplified manner with high efficiency. It is also an object of the present invention to provide a method of cleaning and disinfecting the contact lens wherein the cleaning and disinfection of the contact lens can be effected simultaneously in a short period of time by using the above-indicated cleaning and disinfecting solution. The above objects may be obtained according to one aspect of the present invention which provided a cleaning and disinfecting solution for a contact lens comprising an effective amount of proteolytic enzyme, 60-80% w/v % of propylene glycol, 10-35% w/v % of glycerine, and water, a total content of propylene glycol and glycerine being in the range of 70% to 95 w/v %.

Abstract: An ophthalmically acceptable solution and a method useful for disinfecting and/or cleaning a contact lens. The solution comprises an oxidizing agent and a polyvinyl pyrrolidone having a molecular weight ranging from 10,000 to 100,000 daltons and reactive towards a chlorite oxidizing agent. The end groups of the polyvinyl pyrrolidone are preferably aldehydes. The oxidizing agent of this invention preferably is selected from the group comprising chlorine oxides. The solution preferably has a pH ranging from about 6 to about 8.5. The method of the invention comprises the steps of forming this solution and then contacting a contact lens with the solution.

Abstract: A method for removing residues including waxes, oils, greases, resins, fluxes, diamond lapping compounds and solvent soluble resists from the surface of electronic components, optic elements, contact lenses and metals comprises the steps of contacting the surface with a solution consisting of from 60% to 100% of liquid n-paraffins, iso-paraffins or a mixture thereof having hydrocarbon chain lengths substantially in the range of from C.sub.9 to C.sub.16, from 0% to about 40% paraffin emulsifying agents and from 0% to about 25% d-limonene, allowing the solution to solubilize the residues and removing the solution from the surface.

Abstract: A composition for cleaning and wetting contact lenses comprising a non-amine polyethylenoxide-containing copolymeric material having a hydrophilic-lipophile balance (HLB) of at least about 18, a surface active agent having cleaning activity for contact lens deposits and having HLB values of less than 18, and a wetting agent. Preferred embodiments of the present invention include those having from about 0.001 to about 10 weight percent of a non-amine polyethyleneoxy-containing materials, particularly those selected from: ethoxylated glucose derivatives, ethoxylated ethers of sorbitol, copolymers comprising ethyleneoxy and propyleneoxy monomeric units, and mixtures thereof. Preferred embodiments further include from about 0.001 to about 5 weight percent of the surface active agent and from about 0.1 to about 10 weight percent of a wetting agent selected from: cellulosic materials, silicone polymers containing an alkyleneoxide side chain, polyvinyl alcohols, polyvinyl pyrrolidones, and mixtures thereof.

Abstract: The present invention provides methods for treating contact lenses and compositions for the same. The present invention includes contacting a lens with an aqueous solution comprising a sulfobetaine compound represented by the formula: ##STR1## wherein: R.sub.1 is an alkyl group having from 8 to 30 carbon atoms, R.sub.2 and R.sub.3 are individually hydrogen or alkyl groups having from 1 to 4 carbon atoms, and R.sub.4 is an alkyl group having from 2 to 6 carbon atoms. In preferred embodiments of the invention, the subject compounds are used in combination with antimicrobial agents for providing simultaneous disinfection and cleaning of contact lenses.

Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.

Abstract: Compositions and methods for caring for a contact lens include an inositol phosphate component in an amount effective to at least facilitate the beneficial treatment of the lens.

Abstract: Compositions and methods useful for disinfecting a contact lens are disclosed. The present methods comprise contacting a contact lens with a liquid medium containing an effective amount of an oxidative disinfectant component at conditions to effectively disinfect the contact lens. The contacting occurs in the presence of a color indicator component which is soluble in the liquid medium and is adapted to provide a color indication of the presence of the oxidative disinfectant component in the liquid medium. The color indicator component comprises an effective amount of a transition metal component which is redox active, has an oxidized state of a first color and a reduced state of a different second color and a polyanionic component in an amount effective to inhibit the staining of the contact lens by the transition metal component.

Abstract: Compositions and methods are provided for cleaning and wetting of contact lenses, especially rigid, gas-permeable contact lenses. The compositions comprise low molecular weight polyalkylene oxide modified siloxanes, which are particularly effective in removing lipids from the surface of contact lenses.

Abstract: A composition for cleaning contact lenses comprises a silicone surface active agent having cleaning activity for contact lens deposits. The silicone surface active agent has at least one side chain including a radical ionizable in aqueous solution.

Abstract: A composition for cleaning and wetting contact lenses comprises a polyethyleneoxide-containing material having a hydrophile-lipophile balance (HLB) of at least about 18, a surface active agent having cleaning activity for contact lens deposits, and a wetting agent.

Abstract: A composition and method useful to quickly and effectively indicate whether a functional component such as catalase has been added to a clear solution such as a hydrogen peroxide solution involves compounding with the functional component an effective amount of vitamin B-12 such that when the compounded composition is added to the clear solution, the clear solution turns rose colored. By observing the rose color, the user can determine that the functional component has been added to the clear solution.

Abstract: A pH controlled protein removal system and method in the substantial absence of (a) enzyme and (b) a surfactantly effective amount of a surfactant is disclosed. The method comprises contacting a substrate with a cleaning composition therefor, which compostion is substantially free of (a) enzyme and (b) surfactantly effective amount of a surfactant, for a period of time at an alkaline pH and removing said substrate from said composition.

Abstract: The use of certain amidoamines to disinfect contact lenses and preserve ophthalmic compositions is described, Ophthalmic compositions containing these compounds as disinfecting agents or preservatives are also described, The amidoamines utilized in the present invention have potent antibacterial and antifungal activity, and are chemically compatible with inorganic ions and other materials utilized in ophthalmic compositions.

Abstract: Compositions and methods are provided for cleaning and wetting of contact lenses, especially rigid, gas-permeable contact lenses. The compositions comprise low molecular weight polyalkylene oxide modified siloxanes, which are particularly effective in removing lipids from the surface of contact lenses.