Ascorbic Acid Or Derivative (e.g., Vitamin C, Etc.) Patents (Class 514/474)
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Publication number: 20100099636Abstract: A hydrous gel substantially comprising at least two polymers selected from the group consisting of polyacrylic acid, sodium polyacrylate and partially neutralized polyacrylate, and water, the polymers being crosslinked by containing an aluminum compound, wherein the pH when the hydrous gel is 100-fold diluted with purified water is from 6.5 to 8.5. A hydrous gel which can stably hold an ascorbic acid or a derivative thereof, has high gel strength, exhibits good adhesion to an adherend and causes no liquid syneresis can be provided.Type: ApplicationFiled: December 18, 2009Publication date: April 22, 2010Applicant: SHOWA DENKO K.K.Inventor: Tetsuya ISHII
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Publication number: 20100098752Abstract: Compositions and methods for administering one or more antioxidants to a human subject have been developed. The antioxidant-containing lipid vesicles of the invention provide a delivery system for antioxidants which can be applied topically to the skin.Type: ApplicationFiled: January 18, 2008Publication date: April 22, 2010Inventor: Mark A. Pinsky
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Publication number: 20100092446Abstract: It is an object of the present invention to provide a drug solution which has a reduced dissolved oxygen content and is less susceptible to oxidative degradation and highly stable over time, a production method therefor, and a drug solution containing pack which is capable of maintaining the dissolved oxygen content of a drug solution at a reduced level, less susceptible to oxidative degradation of the drug solution and highly stable over time. To achieve the aforementioned object, the reduced-dissolved-oxygen-content drug solution is produced by filling and sealing the drug solution in a drug solution container (15) formed of a plastic material having an oxygen permeability of not lower than 200 cm3/m2·24 h·atm at 25° C. at 60% RH within 12 hours after a steam sterilization process or a hot water sterilization process and having a steady-state oxygen permeability of not higher than 100 cm3/m2·24 h·atm at 25° C.Type: ApplicationFiled: October 25, 2007Publication date: April 15, 2010Inventors: Nobuaki Sumiyoshi, Isamu Tateishi, Hitoshi Mori, Yasushi Morimoto
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Patent number: 7695732Abstract: The invention pertains to a method of treating or preventing pressure ulcers, comprising enterally administering to a subject in need thereof a composition comprising proteins, carbohydrates, fats, arginine or equivalents thereof, ascorbic acid equivalents and ?-tocopherol equivalents, wherein arginine or equivalents thereof is administered in a daily amount of 3-15 g, ascorbic acid equivalents are administered in a daily amount of 180-840 mg and ?-tocopherol equivalents are administered in a daily amount of 50-400 mg.Type: GrantFiled: November 22, 2004Date of Patent: April 13, 2010Assignee: N.V. NutriciaInventors: Maria Anna Verheul-Koot, Chantal Nelleke Kleijer, Robert Johan Joseph Hageman, Roelof Andre Bork, Maud Goethals
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Patent number: 7696219Abstract: The present invention relates to compositions and methods for treating the nutritional deficiencies observed in patients suffering from renal disease and associated disorders. Specifically, the method involves administering to a renal patient a composition comprising vitamin C, vitamin E, B-complex vitamins, selenium, and zinc.Type: GrantFiled: October 15, 2004Date of Patent: April 13, 2010Assignee: Everett Laboratories, Inc.Inventors: John A. Giordano, Charles J. Balzer
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Publication number: 20100087520Abstract: Liquid orlistat-containing fill materials suitable for encapsulating in hard or soft capsules are described herein. The fill material contains orlistat dissolved in one or more medium chain triglycerides or medium chain partial triglycerides, one or more citrate esters, and combinations thereof. The fill material can also contain one or more pharmaceutically acceptable excipients. In one embodiment, the fill material is substantially free of surfactants. The fill material can be encapsulated in hard or soft, gelatin or non-gelatin capsules. The capsules may be coated to modify release of orlistat from the capsule. Alternatively, the fill material can be encapsulated in an enteric capsule, wherein the enteric polymer is a component of the capsule shell, rather than a coating over the capsule shell. The fill materials are stable at elevated temperatures over an extended period of time and allow for high loadings of orlistat (e.g., 20% w/w or higher).Type: ApplicationFiled: October 6, 2009Publication date: April 8, 2010Inventors: Zhi Liu, Dana S. Toops, Aqeel A. Fatmi
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Patent number: 7691903Abstract: The invention relates to a composition for topical use containing at least one oxidation sensitive hydrophilic active principle and at least one maleic anhydride copolymer, comprising one or more maleic anhydride comonomers and one or more comonomers selected from the group consisting of vinyl acetate, vinyl alcohol, vinylpyrrolidone, olefins containing from 2 to 20 carbon atoms, and styrene, in a physiologically acceptable medium containing an aqueous phase. The invention also relates to the use of a maleic anhydride copolymer as defined above for stabilizing an oxidation-sensitive hydrophilic active principle, in particular in the aqueous phase.Type: GrantFiled: June 18, 2003Date of Patent: April 6, 2010Assignee: L'OrealInventor: Bruno Biatry
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Publication number: 20100080762Abstract: The present invention relates to an oral composition containing an optimal combination of nutritional ingredients at high concentrations and at optimal ratios in order to maintain and/or achieve health and/or beautiful look of the skin.Type: ApplicationFiled: September 5, 2007Publication date: April 1, 2010Inventor: Regina Goralczyk
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Publication number: 20100080856Abstract: A composition and a method for administering the composition to a patient in order to accelerate wound healing, particularly postoperative wound healing. The composition, which essentially comprises ornithine ?-ketoglutarate, is water-soluble and formulated for oral administration in single-dose packets. The method for using the composition for promoting wound healing includes the step of administering the composition to a patient preoperatively as well as-postoperatively in accordance with a prescribed protocol. The composition may be customized to include one or more additional agents that are effective for promoting nutritional health and/or treating a particular medical problem. The composition may also be taken daily by athletes to minimize the healing time of closed wounds such as muscle or tendon tears that occur during participation in sports, even when the symptoms of such injury are subclinical.Type: ApplicationFiled: September 26, 2008Publication date: April 1, 2010Inventor: Peter D. Costantino
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Publication number: 20100080764Abstract: A basic facial and body treatment cosmetic formulation is a combination of a cationic emulsifying agent, an oil soluble liquid polymer and a naturally occurring lactate buffer system. The basic formulation is a starter system that can be specialized to skin moisturizers, skin lighteners, skin pigmenting agents, sunscreens, antioxidants, line reducing products, wrinkle reducing products, anti-cellulite products, pharmaceuticals and the like.Type: ApplicationFiled: September 28, 2009Publication date: April 1, 2010Inventor: Charles Fox
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Patent number: 7687485Abstract: The present disclosure relates to novel compositions which provide improved nutritional support for premenopausal and menopausal women and/or relief from symptoms associated with menopause, as well as prophylactic effects, and methods for using same.Type: GrantFiled: March 27, 2002Date of Patent: March 30, 2010Assignee: Drug Tech CorporationInventors: R. Saul Levinson, Marc S. Hermelin, Mitchell I. Kirschner
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Publication number: 20100069476Abstract: Compositions and methods are provided in which a topical hydrophilic formulation includes a catechin and a hydrophilic antioxidant in a hydrophilic composition at a ratio of between 2.3 to 1.7 (by weight), ad wherein the catechin and the antioxidant are present in an amount such that application of the composition to skin will deposit the catechin at a dosage of between 0.7 mg/cm2 and 1.3 mg/cm2. Especially preferred catechins include green tea catechins, and particularly EGCG, while preferred antioxidants include ascorbic acid and derivatives thereof.Type: ApplicationFiled: May 17, 2005Publication date: March 18, 2010Applicant: MITSUI NORIN CO., LTDInventors: Yukihiko HARA, Santosh K. Katiyar
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Publication number: 20100069485Abstract: A process and a composition to extend the freshness of fruits and vegetables are disclosed. The method comprises treating fresh fruit or vegetable structures with a solution comprising organic acids including N-acetyl cysteine.Type: ApplicationFiled: April 25, 2006Publication date: March 18, 2010Inventors: John Xianrong Liu, Virginia Margarita Fraga, Thomas Young
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Publication number: 20100062087Abstract: In an embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals suffering from diabetes. In another embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, fr-??s-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to enhance wound healing in mammals suffering from diabetes. In an alternative embodiment of the present invention, a nutraceutical formula comprising a combination of two or more substances from the group: berry extract, chromium, zinc, trans-resveratrol, l-arginine, chlorophyll, vitamin C and aloe vera combined synergistically to reduce inflammation in mammals not suffering from diabetes.Type: ApplicationFiled: June 4, 2007Publication date: March 11, 2010Applicant: Interhealth Nutraceuticals, Inc.Inventors: Xiaoming Xu Chien, Debasis Bagchi
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Publication number: 20100047326Abstract: A multiple-compartment ascorbic acid delivery unit is provided. The first compartment is impermeable to oxygen and ultraviolet light and contains a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters. The second compartment is liquid impermeable and contains a pharmaceutically acceptable carrier system. The first compartment is entirely enclosed within said second compartment or vice versa. An opening is formed in the inner compartment in order to combine the contents of the two compartments to form an ascorbic acid carrier composition prior to delivery to the patient.Type: ApplicationFiled: August 21, 2008Publication date: February 25, 2010Inventors: John C. Castel, R. Patrick Abergel
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Publication number: 20100047297Abstract: Provided are cosmetic preparations for topical application containing nanocrystals of cosmetic actives leading to an increased bioactivity of the molecules in the skin and methods of making the cosmetic preparations. The nanocrystals can be added to any cosmetic topical formulation, e. g. creams, lotions and liposomal dispersions. The drug nanocrystals are produced by a combination process of low energy pearl milling followed by a high energy high-pressure homogenization leading to nanocrystal suspensions (nanosuspensions) of improved physical stability.Type: ApplicationFiled: November 19, 2007Publication date: February 25, 2010Applicant: ABBOTT GMBH & CO. KGInventor: Rolf Petersen
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Patent number: 7666904Abstract: The present invention provides a compound of formula I and the use thereof for the inhibition of bacterial cell wall biosynthesis and for the therapeutic treatment of bacterial infection or disease in a patient in need thereof. The present invention also provides the use of the formula I compound for the control of ecto- or endoparasites in homeothermic animals.Type: GrantFiled: September 19, 2008Date of Patent: February 23, 2010Assignee: Wyeth LLCInventors: Craig Eugene Caufield, Schuyler Adam Antane, Koi Michele Morris, Shaughnessy McGrath Naughton, Dominick Anthony Quagliato, Patrick Michael Andrae, Annmarie Enos, John F. Chiarello
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Publication number: 20100034901Abstract: The invention provides compositions and methods for preventing and treating osteochondrosis, lameness, and leg weakness by administration of supplemental boron and vitamin C containing compounds to animals and humans. The supplemental boron and vitamin C containing compounds are provided in animal feed compositions or as supplements for animal feed. Also provided by this invention are animal feed compositions that are supplemented with boron and vitamin C containing compounds and which have reduced phosphorus content. The invention also provides a method for decreasing the amount of phosphorus excreted by an animal, a method of increasing the efficiency of absorption of phosphorus by an animal, a method of reducing environmental phosphorus pollution by administering supplemental boron and vitamin C to the animal.Type: ApplicationFiled: December 6, 2007Publication date: February 11, 2010Applicant: U.S. BORAX, INC.Inventor: Edgar Wayne Johnson, JR.
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Patent number: 7658914Abstract: A composition comprising, per liter of aqueous solution, from 30 to 350 g polyethylene glycol, from 3 to 20 g of an ascorbic acid component selected form the group consisting of ascorbic acid, a salt of ascorbic acid, or a mixture thereof, an alkali metal or alkaline earth metal sulphate, preferably from 1 to 15 g thereof, and optionally one or more electrolytes selected from sodium chloride, potassium chloride, and sodium hydrogen carbonate, and preferably also comprising flavorings, is effective in cleansing the gut in preparation for a endoscopy, especially colonoscopy. It is safer than conventional sodium phosphate-based gut cleansing compositions, and hence can be used for patients who would be at risk with sodium phosphate-based compositions, and is better tolerated than conventional PEG-based compositions, leading to better patient compliance and enabling effective out-patient use.Type: GrantFiled: December 8, 2006Date of Patent: February 9, 2010Assignee: Norgine BVInventors: Norman Barras, Ian David Cox, Alex Ungar, Marc Halphen
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Publication number: 20100028318Abstract: The present invention has its object to provide a safer and highly effective composition capable of relieving or preventing xerostomia. The present invention relates to an agent for relieving or preventing xerostomia comprising an oxidized coenzyme Q and/or a reduced coenzyme Q as active ingredients, a composition containing the agent for relieving or preventing xerostomia in a form of a food product, a health food, a dietary supplement, a supplement, an oral health care product, a medicament, a quasi drug, a pet food, a feed or the like, and a method for treating xerostomia and a method for reducing risks of xerostomia comprising administering the composition.Type: ApplicationFiled: January 31, 2008Publication date: February 4, 2010Applicants: KANEKA CORPORATIONInventors: Ichiro Saito, Kenji Fujii, Kazuya Hamada
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Patent number: 7649017Abstract: The invention relates to the technical fields of biology, pharmacology and medicine. The invention is suitable for use in particular in the human and animal health fields. More specifically, the invention relates to the use of a cAMP modulator in the preparation of compositions that are intended for the prevention or treatment of peripheral neuropathies. The invention further relates to tools and kits to prepare the aforementioned compositions.Type: GrantFiled: July 15, 2003Date of Patent: January 19, 2010Assignees: Universite de la Mediterranee, Institut National de la Sante et de la Recherche Medicale, Association Francaise Contre les MyopathiesInventors: Michel Fontes, Edith Passage, Veronique Sanguedolce, Jean-Chretien Noreel
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Publication number: 20100004329Abstract: An alcohol metabolism enhancer is made from safe plant extracts and an alcoholic beverage and causes a reduced sick feeling and hangover from drinking alcohol without causing hemolysis using safe materials derived from plants. The alcohol metabolism enhancer and the alcoholic beverage include proanthocyanidins, such as pine bark extracts.Type: ApplicationFiled: December 14, 2004Publication date: January 7, 2010Applicant: TOYO SHINYAKU CO., LTD.Inventors: Kinya Takagaki, Takeshi Mitsui
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Publication number: 20100004330Abstract: The present invention relates to a food or drink which provides anti-ageing, anti-cancer, anti-heart disease, vision-enhancing effects of antioxidant substances. This method contains the following anti-oxidative supplements, and is added in food or drink in certain ratio. The method is as follows: adding into a fixed quantity of food or drink an appropriate quantity of the following effective content: vitamin C (water-soluble), ?-carotene (lipid-soluble), lycopene (lipid-soluble), lutein (lipid-soluble) and surfactants. These supplements do not result in mutual interference of absorption and/or biological effect but are more effective in reducing free-radicals.Type: ApplicationFiled: July 2, 2008Publication date: January 7, 2010Inventors: Li Lin Huang, Chris IngYi Huang
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Publication number: 20100003208Abstract: Skin care products which contain as a vitamin C component 6-O-PUFA ascorbates represented by general formula (I): RCO-A??(I) where RCO— is an acyl group derived from a polyunsaturated fatty acid, and A is a residue of ascorbic acid that binds by —O— derived from the hydroxyl group in ascorbic acid. The products show improved transfer of ascorbic acid to tissues or cells, allow the functions of ascorbic acid to be exhibited efficiently, and also have the potential to show the functions of PUFAs. Also provided are foods and beverages that contain 6-O-PUFA ascorbates represented by general formula (I).Type: ApplicationFiled: September 14, 2009Publication date: January 7, 2010Applicant: Suntory Holdings LimitedInventors: Harukazu FUKAMI, Hiroshi Kawashima, Yoshiko Ono
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Publication number: 20090324703Abstract: Curcuminoid formulations having enhanced bioavailability are provided and comprise a curcuminoid, antioxidant, glucuronidation inhibitor, and water-soluble, pharmaceutically acceptable inhibitor. A method of treating Alzheimer's and other age-related diseases by administering such a composition is also provided.Type: ApplicationFiled: March 6, 2007Publication date: December 31, 2009Inventors: Sally A. Frautschy, Gregory M. Cole
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Patent number: 7638507Abstract: Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn's disease, on the other hand, can involve the mucosa of the small and/or large intestine and may involve deeper layers of the bowel wall. The present invention is a combination of 5-aminosalicylic acid and one or more antioxidants (e.g., N-acetylcysteine) for treating such inflammatory bowel diseases.Type: GrantFiled: February 2, 2006Date of Patent: December 29, 2009Assignee: The Board of Regents of the University of OklahomaInventor: Richard F. Harty
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Publication number: 20090311327Abstract: The present, invention provides an oral delivery system for a therapeutic compound that is an acid, a salt of an acid or an unionized compound or a proactive form thereof with pharmacological, physiological or biochemical activity. The present invention particularly provides a swallow formulation comprising a therapeutic compound that is an acid, a salt of an acid or an unionized compound or a proactive form thereof which facilitates the rapid delivery of the therapeutic compound to the circulatory system.Type: ApplicationFiled: November 28, 2006Publication date: December 17, 2009Applicant: IMAGINOT PTY LTDInventors: Michael Stephen Roberts, George Alexander Davidson, Ruoying Jiang, Geraldine Ann Elliott, Keivan Bezanehtak, Stephen Douglas Chandler, Greg Davey, Mantu Sarkar
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Publication number: 20090304824Abstract: A novel rapid-melt composition, including methods of making the same, and methods of using the same for the delivery of prophylactic and therapeutic active materials to a mammal. The rapid-melt compositions are formed by molding or compression, with an additional heating step being preferred.Type: ApplicationFiled: March 24, 2009Publication date: December 10, 2009Applicant: Capricorn Pharma, Inc.Inventor: S. Rao Cherukuri
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Patent number: 7629354Abstract: The use of phanquinone for the manufacture of a pharmaceutical composition for the prevention or the treatment of Alzheimer's disease is disclosed. Also methods of treatment or prevention of Alzheimer's disease are disclosed.Type: GrantFiled: November 18, 2003Date of Patent: December 8, 2009Assignee: Prana Biotechnology LimitedInventors: Michel Xilinas, Panayotis Nikolas Gerolymatos
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Publication number: 20090292015Abstract: The present invention is directed to a polyol-in-oil composition used to transport and stabilize Vitamin C. The composition includes 0.5 wt % to 5 wt % of at least one emulsifier, 0.1 wt % to 5 wt % of at least one stabilizer, 0.01 wt % to 20 wt % of Vitamin C, 10 wt % to 40 wt % of at least one oil component and 40 wt % to 80 wt % of at least one polyol, each based on the mass of the whole composition, wherein the proportion of water in the whole composition is less than 1 wt % and wherein Vitamin C is dissolved in the polyols and the use of this composition.Type: ApplicationFiled: April 29, 2009Publication date: November 26, 2009Applicant: EVONIK GOLDSCHMIDT GMBHInventors: Haizhou Zhang, Jingya Dai, Jiali Zou, Zhiheng Gao
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Publication number: 20090291919Abstract: Methods are disclosed for treating ophthalmic conditions related to the production of toxic visual cycle products that accumulate in the eye, and are associated with reactions of the visual cycle during medical procedures that expose the eye to light, most commonly the various forms of ophthalmic surgery. Compounds and compositions useful in the these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said treatments.Type: ApplicationFiled: January 21, 2009Publication date: November 26, 2009Applicant: University of Florida Research Foundation, Inc.Inventors: Shalesh Kaushal, Syed M. Noorwez
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Publication number: 20090286874Abstract: An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.Type: ApplicationFiled: April 15, 2009Publication date: November 19, 2009Applicant: L'OREALInventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
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Publication number: 20090253785Abstract: A bactericide composition kills Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), Methicillin-resistant Staphylococcus aureus (MRSA) and Propionibacterium acnes (P. acnes) and comprises a solvent and L-ascorbic acid. The L-ascorbic acid is dissolved in the solvent in a range of 1 wt % to 40 wt %. Ascorbic acid (vitamin C) is water-soluble and is essential for people. Thus, ascorbic acid contacting people will not harm them, and if a person inhales ascorbic acid, ascorbic acid will be metabolized and excreted out of person's body. Therefore, the bactericide composition is safe and not harmful to a person's health.Type: ApplicationFiled: January 22, 2007Publication date: October 8, 2009Inventor: Tai-Li Ou
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Publication number: 20090246254Abstract: The present invention relates to a non-hormonal, biocompatible, and biodegradable intravaginal device for the delivery of spermiostatic, spermicidal and anti-infectious agents. The present invention also relates to methods of contraception using such a device, as well as the prevention and treatment of sexually transmitted diseases and vaginal infections through the application of the device.Type: ApplicationFiled: April 3, 2009Publication date: October 1, 2009Inventors: Brij B. Saxena, Mukul Singh, Sidney Lerner
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Publication number: 20090239945Abstract: A composition which is adapted for oral consumption and which comprises: (i) a PPAR ligand; such as EPA or DHA (ii) an oestrogen receptor binding agent; such as soy isoflavones (iii) an agent that is involved in the post-translational modification of collagen; such as ascorbic acid and (iv) a carotenoid, wherein the composition is substantially free from added zinc and/or selenium, can provide an anti-ageing effect on skin and may be used to increase collagen synthesis in skin.Type: ApplicationFiled: March 27, 2007Publication date: September 24, 2009Inventors: John Casey, Gail Jenkins, Julia Sarah Rogers
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Publication number: 20090232756Abstract: A composition in the form of an oil-in-water emulsion containing: an ester of fatty acid and of polyethylene glycol; an additional surfactant chosen from esters of C16-C22 fatty acid and of sorbitan and esters of C16-C22 fatty acid and of glycerol; a polycondensate of ethylene oxide and of propylene oxide consisting of polyethylene glycol and polypropylene glycol blocks; and an ascorbic acid compound or a salicylic acid compound. The composition has good stability, in particular after hours at 55° C. Application in caring for and making up keratinous substances.Type: ApplicationFiled: March 9, 2009Publication date: September 17, 2009Applicant: L'OREALInventor: Aldo MONELLO
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Publication number: 20090214504Abstract: A method for treating a patient suffering from a wound, ulcer, or inflammation includes providing a topical formulation comprising a carrier and a combination of active ingredients that includes at least one retinoid and at least one blood vessel dilator, and applying the topical formulation to the skin of the patient to cause healing, accelerated healing or prevention of the wound, ulcer or inflammation. Additional active ingredients may include a promoter of mitochondrial function or an antioxidant.Type: ApplicationFiled: January 22, 2009Publication date: August 27, 2009Applicant: BIOCHEMICS, INC.Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
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Publication number: 20090209640Abstract: The present invention relates to a method for treating viral infection, which includes administering arginine and a high dose of vitamin C. It also relates to an agent for treating viral infection, which includes arginine and coated vitamin C.Type: ApplicationFiled: April 15, 2009Publication date: August 20, 2009Applicants: Fumie MORISHIGE, LIFE SCIENCE INSTITUTE, LTD., CHOKO CO., LTD.Inventor: Fukumi Morishige
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Patent number: 7575856Abstract: The present invention describes devices, solutions, and methods for the ex-vivo assessment, resuscitation, triage, and maintenance of human candidate cadaveric hearts.Type: GrantFiled: October 28, 2005Date of Patent: August 18, 2009Assignees: The United States of America as represented by the Department of Veterans Affairs, President and Fellows of Harvard CollegeInventors: Shukri Khuri, Hemant Thatte, Vladimir Birjinuik
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Publication number: 20090197948Abstract: The present invention is to provide a skin external preparation with good moisture retention, a rough skin improving effect, and an improved feeling in use. A skin external preparation comprising a polyoxyalkylene glycol/polyethylene glycol copolymer alkyl ether derivative represented by the below-described general formula (I): (formula I) Y—{O(EO)a/(AO)b—R}k??(I) (In the formula, Y is the residue given by removing hydroxyl groups from a polyhydric alcohol having 3 to 6 hydroxyl groups, and k is the number of hydroxyl groups of the polyhydric alcohol. EO is an oxyethylene group; AO is an oxyalkylene group having 3 to 4 carbon atoms, and 1?a?70, 1?b?70. The percentage of the oxyethylene groups with respect to the sum of the oxyalkylene groups having 3 to 4 carbon atoms and the oxyethylene groups is 20 to 100 mass %. The oxyalkylene group having 3 to 4 carbon atoms and the oxyethylene group are added randomly.Type: ApplicationFiled: May 22, 2007Publication date: August 6, 2009Applicants: Shiseido Co., Ltd., NOF CorporationInventors: Reiji Miyahara, Kouzou Hiwatari, Kei Watanabe, Takashi Oka, Kei-ichi Maruyama, Keiichi Yokozawa
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Publication number: 20090197946Abstract: A composition, employed topically for its microbicidal, spermatocidal activity upon application to the human genitalia and/or anorectal area, and the prophylaxis of sexually transmitted diseases, contraception, and the relief from symptoms of local inflamation and infection. The embodiment incorporates L-Ascorbic acid in a concentration of about 2% to about 25% wt/vol, within an acidic range or pH level of about 4.0 to 2.0 pH respectively, in an aqueous solution with a pharmaceutically acceptable liquid carrier. In alternative exemplary embodiments the composition is in a specified physical state and predetermined composition for the desired therapeutic effect. Additionally, the composition in alternative embodiment includes a synergistic antioxidant and further incorporates enhancing bioactive ingredients.Type: ApplicationFiled: January 31, 2008Publication date: August 6, 2009Inventor: Joseph Di Bartolomeo
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Patent number: 7566698Abstract: The present invention provides a novel ascorbic acid derivative as a provitamin C with improved stability in the body and prolonged life in the body compared to conventionally known 2-O-(?-D-glucopyranosyl)ascorbic acid. The composition comprising the novel compound 2-O-(?-D-glucopyranosyl)ascorbic acid has been extracted from plants such as from Ningxia Lycium barbarum L. and/or Lycium chinense Mill. The compositions comprising 2-O-(?-D-glucopyranosyl)ascorbic acid may be enzymatically synthesized using ?-D-glucosyltransferase. Pure 2-O-(?-D-glucopyranosyl)ascorbic acid may be produced from such compositions. Alternatively, 2-O-(?-D-glucopyranosyl)ascorbic acid may be produced by chemical synthesis. The 2-O-(?-D-glucopyranosyl)ascorbic acid results in higher stability and a prolonged life of vitamin C when ingested in the body compared to the corresponding ?-D-glucopyranosyl derivative, and is therefore highly suitable as a provitamin C to be used in cosmetics and foods.Type: GrantFiled: December 27, 2002Date of Patent: July 28, 2009Assignee: Suntory Holdings LimitedInventors: Mitsuru Maeda, Masahiro Nakao, Harukazu Fukami
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Publication number: 20090181084Abstract: An oral fast-disintegrating tablet includes many tiny particles of slowly-releasable ascorbic acid, and a fast-disintegrating ingredient mixed with the many tiny particles that are dispersedly mixed with the fast-disintegrating ingredient. Each tiny particle is composed of a nucleus, an ascorbic layer and a release-control layer. The nucleus is coated with the ascorbic-acid layer and then with the releasing control layer to become a slowly-releasable particle. The tiny particles are mixed with the fast-disintegrating ingredient, which is composed of a mixture of ascorbic acid, water excipient, microcrystalline cellulose, a diluent agent, and disintegrant. So the tablet can be disintegrated swiftly in a mouth, and the tiny particles can enter the stomach and intestines with saliva to be slowly released, sustainingly absorbed by the organs.Type: ApplicationFiled: January 15, 2008Publication date: July 16, 2009Inventor: Ta-Ping Liao
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Publication number: 20090180974Abstract: The invention relates to an agent or a composition for protecting body cells for the preventive and/or performance-enhancing influencing of body cells. The agent comprises a combination of herbal active substances and vitamins and amino acids, with one active substance consisting of polyphenols from green tea.Type: ApplicationFiled: October 23, 2006Publication date: July 16, 2009Inventor: Hans-Emanuel Holzgang
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Patent number: 7560123Abstract: The present invention relates to compositions that may be swallowable, chewable or dissolvable, comprising various vitamins and minerals, and in a specific embodiment comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and methods for using these compositions for nutritional supplementation in subjects undergoing physiologically stressful events, such as, for example and without limitation, pregnancy, lactation or any disease state.Type: GrantFiled: August 12, 2004Date of Patent: July 14, 2009Assignee: Everett Laboratories, Inc.Inventors: John A. Giordano, Charles J. Balzer
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Publication number: 20090176715Abstract: The present invention provides a pharmaceutical composition for oral administration comprising a D-amino acid combined with an antioxidant selected from the group consisting of vitamin E, vitamin C, a glutathione or a precursor thereof.Type: ApplicationFiled: January 8, 2009Publication date: July 9, 2009Applicant: Amino Acids Solutions Inc.Inventor: Daniel Javitt
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Publication number: 20090170932Abstract: Disinfectant compositions comprising N-Acetyl Cysteine (NAC) and Vitamin C are disclosed. The disinfectant compositions have also demonstrated activity in inhibiting as well as killing micro-organisms responsible for generating biofilms. They are safe for human and medical uses and may be used as prophylactic preparations to reduce the proliferation of and/or eliminate existing or established infections.Type: ApplicationFiled: December 31, 2008Publication date: July 2, 2009Applicant: Tyco Healthcare Group LPInventors: Dinesh AGGARWAL, Chirag Shah
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Publication number: 20090156581Abstract: Pharmaceutical compositions and method using aminergic compounds and complement compounds. Compositions are provided comprising: (a) a subefficacious amount of a non-adrenergic aminergic compound or of an adrenergic antagonist; and (b) a safe and effective amount of a complement compound. Methods are also provided comprising the administration of: (a) a low dose of a non-adrenergic aminergic compound or of any adrenergic antagonist; and (b) a safe and effective amount of a complement compound. Non-adrenergic aminergic compounds can comprise a histaminergic, dopaminergic, muscarinergic, serotoninergic, octopaminergic, or trace aminergic compound. Complement compounds include ascorbates, opioids, polycarboxylic acid chelators, resveratrols, cysteines, substituted derivatives and analogs thereof, and mixtures thereof. Preferred complements include ascorbates, particularly ascorbic acid.Type: ApplicationFiled: April 14, 2006Publication date: June 18, 2009Applicant: BOARD OF TRUSTREES OF MICHIGAN STATE UNIVERSITYInventors: Patrick F. Dillon, Robert S. Root-Bernstein
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Publication number: 20090155393Abstract: A method for increasing the longevity of an old animal comprising administering to the animal a composition comprising one or more antioxidants in a total antioxidant amount sufficient to increase the longevity of the animal.Type: ApplicationFiled: July 14, 2006Publication date: June 18, 2009Inventors: Steven Curtis Zicker, Karen Joy Wedekind
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Publication number: 20090142314Abstract: The use of docosahexaenoic acid in the manufacture of a composition for administration to a pregnant woman for reducing the risk of development of overweight or obesity of the baby in infancy and/or early childhood.Type: ApplicationFiled: May 22, 2007Publication date: June 4, 2009Applicant: NESTEC S.A.Inventors: Ferdinand Haschke, Zdenek Kratky