Ester Doai Patents (Class 514/506)
  • Patent number: 4716175
    Abstract: Certain substituted amides of saturated fatty acids are potent inhibitors of the enzyme acyl-CoA:cholesterol acyltransferase and are thus useful agents for inhibiting the intestinal absorption of cholesterol.
    Type: Grant
    Filed: February 24, 1987
    Date of Patent: December 29, 1987
    Assignee: Warner-Lambert Company
    Inventors: Milton L. Hoefle, Ann Holmes, Bruce D. Roth
  • Patent number: 4594243
    Abstract: A composition capable of promoting the skin permation or percutaneous absorption of a medicament, which comprises at least one adjuvant selected from the group consisting of a saturated hydrocarbon containing 5 to 20 carbon atoms which may be substituted by halogen, an alcohol ester of aliphatic carboxylic acid containing 12 to 18 carbon atoms, an ether, a dimethylpolysiloxane having a viscosity at 25.degree. C. of not more than 6 centistokes and a cyclic polydimethylsiloxane having a viscosity at 25.degree. C. of not more than 6 centistokes, and an imidazolidinone derivative represented by the general formula: ##STR1## wherein R.sub.1 and R.sub.2 each are a lower alkyl group; and pharmaceutical composition for external medication.
    Type: Grant
    Filed: July 25, 1984
    Date of Patent: June 10, 1986
    Assignee: Nitto Electric Industrial Co., Ltd.
    Inventors: Susumu Satoh, Ichiro Kobayashi, Yumiko Takakura, Mitsuru Tamada