Polymer From Ethylenic Monomers Only Patents (Class 514/772.4)
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Publication number: 20130210932Abstract: Positive latex including an oil phase, an aqueous phase, at least one water-in-oil emulsifying system, and a linear, branched or cross-linked cationic polyelectrolyte resulting from the polymerization, for 100 mol %, of: a) a molar ratio >40% and ?99% of monomer units originating from at least one cationic monomer; b) a molar ratio ?1% and <60% of monomer units originating from N-(2-hydroxyethyl)acrylamide; c) optionally, a molar ratio >0% and <30% of monomer units originating from at least one neutral monomer other than the N-(2-hydroxyethyl)acrylamide, on the condition that the molar ratio is strictly less than that of the monomer units originating from N-(2-hydroxyethyl)acrylamide; and d) optionally, a molar ratio >0% and ?1% of a diethylene or polyethylene cross-linking monomer. A method for preparing and using the positive latex as a thickener for cosmetic or pharmaceutical compositions is also described.Type: ApplicationFiled: November 28, 2011Publication date: August 15, 2013Applicant: Societe D'Exploitation De Products Pour Les Industries Chimiques SEPPICInventors: Olivier Braun, Paul Mallo
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Publication number: 20130203865Abstract: Elastomeric polymers and compounded elastomers having reduced amounts of leachables and improved resistance to ?-irradiation sterilization suitable for pharmaceutical stopper and seal applications. These polymers and compounded elastomers maintain their physical performances upon being exposed to ?-irradiation over time and typical use conditions. The polymer is prepared by reacting a mixture of i) a C4 to C7 isoolefin monomer, ii) a styrene based monomer, and optionally iii) a C4 to C14 multiolefin monomer wherein the polymer contains 5 to 15 wt % of styrene derived units.Type: ApplicationFiled: August 9, 2012Publication date: August 8, 2013Inventors: Wai K. Wong, Bharat B. Sharma, Bernard D'Cruz
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Patent number: 8501231Abstract: A drug in a solubility-improved form is combined with a concentration-enhancing polymer in a sufficient amount so that the combination provides substantially enhanced drug concentration in a use environment relative to a control comprising the same amount of the same solubility-improved form of drug without the concentration-enhancing polymer.Type: GrantFiled: June 19, 2012Date of Patent: August 6, 2013Assignee: Bend Research, Inc.Inventors: William J. Curatolo, Ravi M. Shanker, Walter C. Babcock, Dwayne T. Friesen, James A. S. Nightingale, Douglas A. Lorenz
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Publication number: 20130195954Abstract: Described herein are compounds and processes that can be used to prepare polymer-based films, particles, gels and related compositions, and processes for delivery of agents, and other uses.Type: ApplicationFiled: November 8, 2012Publication date: August 1, 2013Applicants: THE TRUSTEES OF THE BOSTON UNIVERSITY, THE BRIGHAM AND WOMEN'S HOSPITALInventors: The Brigham and Women's Hospital, The Trustees of the Boston University
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Publication number: 20130195769Abstract: The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such compositions. The foamable composition includes at least one solvent selected from a hydrophobic solvent, a silicone oil, an emollient, a co-solvent, and mixtures thereof, wherein the solvent is present at a concentration of about 70% to about 96.5% by weight of the total composition, at least a non-ionic surface-active agent at a concentration of about 0.1% to less than about 10% by weight of the total composition; at least one gelling agent at a concentration of about 0.1% to about 5% by weight of the total composition; a therapeutically effective amount of at least one active agent; and at least one liquefied or compressed gas propellant, at a concentration of about 3% to about 25% by weight of the total composition.Type: ApplicationFiled: March 11, 2013Publication date: August 1, 2013Applicant: FOAMIX LTD.Inventor: Foamix Ltd.
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Publication number: 20130190839Abstract: An implantable drug-doped component, e.g., a cochlear implant, includes host material, a host-embedded drug and a sacrificial material integrated with the host. Upon exposure of the sacrificial material to a solvent, e.g., perilymph fluid, voids in the host are created which facilitate release of the drug. The host can be, e.g., polysiloxane or silicone rubber. The sacrificial material, e.g., can be a glucose monomer, sugar, cyclodextrin, a salt, a bioresorbable material, hyaluronic acid, polyurethane, polyester, polyamide, polyvinyl alcohol, polyacrylic acid, etc. Alternatively, the sacrificial material can be the host, and can facilitate release of the drug through changing a property of the sacrificial material, e.g., by exposing the component to an ethanol wash. For a cochlear implant, e.g., the drug doped material can be applied to a non-stimulating surface of the electrode array.Type: ApplicationFiled: January 20, 2012Publication date: July 25, 2013Inventors: Jane Rapsey, Martin Svehla, Peter Schuller, Christopher Robert Miller
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Publication number: 20130189313Abstract: Described herein is the synthesis of adhesive complex coacervates and their use thereof. The adhesive complex coacervates are composed of a mixture of one or more polycations and one or more polyanions. The polycations and polyanions in the adhesive complex coacervate are crosslinked with one another by covalent bonds upon curing. The adhesive complex coacervates have several desirable features when compared to conventional bioadhesives, which are effective in water-based applications. The adhesive complex coacervates described herein exhibit good interfacial tension in water when applied to a substrate (i.e., they spread over the interface rather than being beaded up). Additionally, the ability of the complex coacervate to crosslink intermolecularly increases the cohesive strength of the adhesive complex coacervate.Type: ApplicationFiled: September 14, 2012Publication date: July 25, 2013Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATIONInventors: Russell J. Stewart, Hui Shao
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Patent number: 8481058Abstract: A tropical composition is provided. The topical composition can be prepared by diluting a topical composition precursor with water and adding additional components, if desired. The topical composition precursor can be prepared by melt processing a hydrophobic polymer composition that includes repeating pyrrolidone/alkylene groups wherein the alkylene groups contain at least 10 carbon atoms, and a hydrophilic polymer composition including repeating carboxylic groups and/or repeating hydroxyl groups. A topical composition precursor and methods for manufacturing and using a topical composition are provided by the invention.Type: GrantFiled: May 23, 2002Date of Patent: July 9, 2013Assignee: Skinvisible Pharmaceuticals, Inc.Inventor: Bruce Jezior
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Patent number: 8470892Abstract: A method for inducing neovascularization in which a pharmaceutically effective amount of polyethylene glycol (PEG) is injected into the tissue of the subject for purposes of accelerating wound healing and mimicking age related macular degeneration, cancer, tumors, and atherosclerosis for further research purposes.Type: GrantFiled: August 10, 2010Date of Patent: June 25, 2013Inventors: Puran S. Bora, Nalini S. Bora
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Publication number: 20130150460Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.Type: ApplicationFiled: January 4, 2013Publication date: June 13, 2013Applicant: Advanced Cardiovascular Systems, Inc.Inventor: Advanced Cardiovascular Systems, Inc.
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Publication number: 20130150459Abstract: A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.Type: ApplicationFiled: January 4, 2013Publication date: June 13, 2013Applicant: Advanced Cardiovascular Systems, Inc.Inventor: Advanced Cardiovascular Systems, Inc.
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Publication number: 20130129797Abstract: Described herein are polymeric compositions that comprise at least one polymer residue and at least one crosslinking moiety, wherein the polymer residue is crosslinked by the crosslinking moiety and wherein the crosslinking moiety is formed from a reaction between a boronic acid moiety and a hydroxamic acid moiety. Also, described are methods of making and using such polymeric compositions.Type: ApplicationFiled: January 16, 2013Publication date: May 23, 2013Applicant: University of Utah Research FoundationInventor: University of Utah Research Foundation
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Patent number: 8445011Abstract: Methods and compositions for reducing the frequency of urination are disclosed. One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising an analgesic agent formulated in a delayed-release formulation. Another method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising multiple active ingredients. Yet another method comprises administering to a subject in need thereof an effective amount of a diuretic followed with another administration of an pharmaceutical composition comprising an analgesic agent.Type: GrantFiled: July 27, 2012Date of Patent: May 21, 2013Assignee: Wellesley Pharmaceuticals, LLCInventor: David A. Dill
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Publication number: 20130121944Abstract: The present invention relates to a thickener preparable by a process which comprises obtaining a cationic polymer by inverse emulsion polymerization of a) at least one water-soluble ethylenically unsaturated monomer comprising at least one cationic monomer, optionally at least one anionic monomer and/or optionally at least one nonionic monomer, b) at least one ethylenically unsaturated associative monomer, c) optionally at least one crosslinker, d) optionally at least one chain transfer agent, the temperature being kept constant during the inverse emulsion polymerization and being at least 40° C., preferably 50 to 90° C., and after the inverse emulsion polymerization has ended, activator being added to obtain the thickener.Type: ApplicationFiled: November 7, 2012Publication date: May 16, 2013Applicant: BASF SEInventors: Reinhold J. Leyrer, Christofer Arisandy, Ouidad Benlahmar
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Publication number: 20130121945Abstract: The present invention relates to a thickener comprising i) at least one polymer preparable by polymerization of a) at least one water-soluble ethylenically unsaturated monomer comprising at least one anionic monomer and/or at least one nonionic monomer, b) at least one ethylenically unsaturated associative monomer, c) optionally at least one crosslinker, d) optionally at least one chain transfer agent, ii) at least one activator, where the ratio of activator to polymer is >10 to 100 [% by weight/% by weight].Type: ApplicationFiled: November 7, 2012Publication date: May 16, 2013Applicant: BASF SEInventor: BASF SE
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Publication number: 20130121942Abstract: The present invention relates to a thickener comprising i) at least one c onic polymer preparable by polymerization of a) at least one water-soluble ethylenically unsaturated monomer comprising at least one cationic monomer, optionally at least one anionic monomer and/or. optionally at least one nonionic monomer, b) at least one e,(hylenically unsaturated associative monomer, c) optionally at ieast one crosslinker, d) optionally at least one chain transfer agent, ii) at least one activator, where the ratio of activator to cationic polymer is >10 to 100 [% by weight/% by weight].Type: ApplicationFiled: November 7, 2012Publication date: May 16, 2013Applicant: BASF SEInventor: BASF SE
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Publication number: 20130121943Abstract: The present invention relates to a thickener preparable by a process wherein a polymer is obtained by an inverse emulsion polymerization of a) at least one water-soluble ethylenically unsaturated monomer comprising at least one anionic monomer and/or at least one nonionic monomer, b) at least one ethylenically unsaturated associative monomer, c) optionally at least one crosslinker, d) optionally at least one chain transfer agent, where the temperature during the inverse emulsion polymerization is kept constant and is at least 40° C., preferably 50 to 90° C., and, when the inverse emulsion polymerization is complete, the activator is added, giving the thickener.Type: ApplicationFiled: November 7, 2012Publication date: May 16, 2013Applicant: BASF SEInventor: BASF SE
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Publication number: 20130102688Abstract: There is provided an oil-in-water emulsion composition whose continuous phase is an aqueous phase, but which has a high moisture evaporation suppressing effect and is also superior in feeling, and a method for producing the same. An oil-in-water emulsion composition containing an oily component having an inorganic value of 2500 or less, an organic value of 5000 or less and an IOB value of 0.3 to 0.5, the oil-in-water emulsion composition containing the following components (A) to (C) in an aqueous phase. (A) a polyoxyethylene alkyl or alkenyl ether having alkyl group or alkenyl group having 20 to 24 carbon atoms and an average molar number of ethylene oxide added of 1.Type: ApplicationFiled: June 3, 2011Publication date: April 25, 2013Applicant: KAO CORPORATIONInventor: Takeshi Murata
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Publication number: 20130102689Abstract: The present invention is directed to stable emulsions comprising polyolefins, in particular polyisobutene, the process to obtain said emulsions and the use of said emulsions.Type: ApplicationFiled: December 5, 2012Publication date: April 25, 2013Applicant: BASF SEInventor: BASF SE
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Publication number: 20130101543Abstract: Disclosed are blends of acrylic polymers comprising at least one crosslinked acrylic copolymer and at least one linear acrylic copolymer. The acrylic polymer blends surprisingly provide desirable rheological, clarity, and aesthetic properties in aqueous surfactant containing compositions, particularly at low pH.Type: ApplicationFiled: July 7, 2011Publication date: April 25, 2013Applicant: LUBRIZOL ADVANCED MATERIALS, INC.Inventors: Krishnan Tamareselvy, Denise W. Rafferty
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Patent number: 8426476Abstract: A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the composition are provided.Type: GrantFiled: September 2, 2010Date of Patent: April 23, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Stephen D. Pacetti
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Publication number: 20130096207Abstract: Provided is a water dispersion type sex pheromone sustained release preparation which makes it possible to suppress excess release at the initial stage of spraying and release a sex pheromone substance at a constant amount for a predetermined period, and which can be sprayed by using a common sprayer. Specifically provided is a water dispersion type sex pheromone sustained release preparation, comprising an insect sex pheromone substance which is enclosed in a ring of a cyclodextrin, an inclusion cyclodextrin which encloses the insect sex pheromone substance, a non-inclusion cyclodextrin which does not enclose the insect sex pheromone substance, a water-soluble polymer, and water.Type: ApplicationFiled: October 2, 2012Publication date: April 18, 2013Applicant: SHIN-ETSU CHEMICAL CO., LTD.Inventor: Shin-Etsu Chemical Co., Ltd.
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Publication number: 20130089671Abstract: The present invention generally relates to a novel polymeric material formed, at least in part, from monomeric material comprising 2,3,3,3-tetrafluoropropene (CF3CF?CH2, 1234yf), to polymeric compositions, to coating compositions, and to uses thereof.Type: ApplicationFiled: October 4, 2012Publication date: April 11, 2013Applicant: HONEYWELL INTERNATIONAL INC.Inventor: HONEYWELL INTERNATIONAL INC.
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Publication number: 20130090237Abstract: In one embodiment, a method includes making a pteredin phenyl pentanedioic (3P) formulation by providing an aqueous solution including one of more 3P molecules neutralized with one or more of an alkali, an alkali earth metal hydroxide, or an alkali carbonate; adding to the aqueous solution one of a surfactant, dispersant, or additive with the guest molecules; and non-covalently crosslinking the 3P formulation by exposing the 3P formulation to an excess solution of multivalent cation salt.Type: ApplicationFiled: October 11, 2011Publication date: April 11, 2013Inventor: Sanat Mohanty
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Publication number: 20130085186Abstract: The present invention relates to cosmetic or dermatological formulations comprising at least one active compound, at least one polymer which is molecularly imprinted in the presence of this active compound and at least one fatty phase.Type: ApplicationFiled: August 6, 2012Publication date: April 4, 2013Applicant: BASF SEInventors: Volker Wendel, Oliver Brüggemann, Arne Ptock
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Patent number: 8409610Abstract: A wound care device for local treatment of pain in a wound, said device comprising an active pain relieving composition, the device being constructed in such a manner that the pain killing agent is released to the wound in such a way that substantially no effective systemic plasma concentration of the pain killing agent can be found and wherein a majority of said pain killing agent is in direct contact with the wound.Type: GrantFiled: September 12, 2011Date of Patent: April 2, 2013Assignee: Coloplast A/SInventors: Gitte Juel Friis, Truels Sterm Larsen
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Patent number: 8409621Abstract: A method of forming particles, comprises accelerating a first stream comprising a first liquid, applying a charging voltage of at most 1.5 kV to the first stream, and vibrating the first stream, to form particles.Type: GrantFiled: November 13, 2007Date of Patent: April 2, 2013Assignee: The Board of Trustees of the University of IllinoisInventors: Kyekyoon Kim, Hyungsoo Choi, Young Bin Choy
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Publication number: 20130059926Abstract: A method for producing polymerisable solution which comprises dissolving an ethylenically unsaturated zwitterionic monomer in a co-monomer system comprising a functionalised ethylenically unsaturated monomer in which the zwitterionic monomer is soluble, a siloxane group-containing monomer or macromer, and a crosslinking agent is disclosed. The polymerisable solution is biocompatible and can be used to produce polymers and articles such as contact lenses.Type: ApplicationFiled: August 31, 2012Publication date: March 7, 2013Inventors: Michael Driver, Qingpu Hou, Jin Hai Wang
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Patent number: 8389011Abstract: A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.Type: GrantFiled: June 12, 2012Date of Patent: March 5, 2013Assignee: Bend Research, Inc.Inventors: Marshall D. Crew, William J. Curatolo, Dwayne T. Friesen, Michael Jon Gumkowski, Douglas A. Lorenz, James A. S. Nightingale, Roger B. Ruggeri, Ravi M. Shanker
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NOVEL SELF-REVERSIBLE REVERSE LATEX, AND USE THEREOF AS A THICKENING AGENT IN A COSMETIC COMPOSITION
Publication number: 20130035401Abstract: A self-reversible reverse latex, and its use as a thickener. The self-reversible reverse latex includes: 50%-70% of a cross-linked polyelectrolyte obtained by the polymerization of a monomer of formula (I), with R1 being 8 to 20 carbon atoms and 1?n?30 for a neutral monomer, and a monomer having an acid function; 4%-10% of a water-in-oil emulsifier; 1%-10% of an oil-in-water emulsifier including a surface-active composition (C); 15%-45% oil; and 0%-5% water. Composition (C) is 10%-50% composition (CII) and 50%-90% composition (CIII). Composition (CII) is 60%-100% of a composition of formula (II), with R2 being a 12 carbon alkyl, T1, T2, and T3 being H or a (—CH2—CH2-0-)mi—H radical with 0?mi?10 and 0<?mi?10. Composition (CIII) is 60%-100% of a compound of formula (III) or mixtures of (III) and (IV), with R2 being as defined previously.Type: ApplicationFiled: April 11, 2011Publication date: February 7, 2013Applicant: SOCIETE DEXPLOITATION DE PRODUCTS POUR LOS INDUSTR CHIMIQUE SEPPICInventors: Olivier Braun, Paul Mallo -
Publication number: 20130018078Abstract: Transdermal drug delivery patches and methods of their production are described. The patches can be made such that the accommodate highly plasticizing drugs such as selegiline and/or the use of protonated forms of various drugs.Type: ApplicationFiled: September 20, 2012Publication date: January 17, 2013Applicant: MYLAN TECHNOLOGIES INC.Inventor: Mylan Technologies Inc.
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Publication number: 20130018110Abstract: The invention provides a method for preparing a hydrogel from a hydrophilic polymer having one or more functional groups which are capable of co-reacting in a condensation reaction which method comprises the steps of: (i) preparing a solution of the polymer; (ii) heating the solution to a temperature sufficient for the condensation reaction to take place for a period of time sufficient for the hydrogel to cross-link wherein where the hydrophilic polymer comprises a first and a second hydrophilic polymer, step (i) comprises a step of mixing the hydrophilic polymers to prepare a homogeneous intimate mixture of the polymers; and wherein the heating step (ii) is carried out at a pressure greater than atmospheric pressure. The method of the invention is advantageous because it is relatively low cost, it is a safer procedure with less health & safety concerns, it is carried out in a liquid state and is not limited by film thickness.Type: ApplicationFiled: January 20, 2011Publication date: January 17, 2013Applicant: The University of ReadingInventors: Vitaliy Khutoryanskiy, Olga Khutoryanskaya, Joseph Peter Cook, Glenn William Goodall
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Publication number: 20130017232Abstract: The disclosure provides Bone-mimetic mineral/polymer composite materials useful for formation of artificial bone grafts and for bone tissue engineering. The disclosure provides a hydrogels, cryogels and macroporous compositions modified with varying lengths of anionic pendant side chains (CH2?CHCONH(CH2)nCOOH, where n=1 to 12).Type: ApplicationFiled: July 13, 2012Publication date: January 17, 2013Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Shyni Varghese, Ameya Phadke
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Publication number: 20130011385Abstract: A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength.Type: ApplicationFiled: December 23, 2010Publication date: January 10, 2013Applicant: AXCELON BIOPOLYMERS COPRORATIONInventors: Xinsheng Li, Wankei Wan, Chandrakant J. Panchal
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Publication number: 20130012598Abstract: Nanofibers are fabricated in a continuous process by introducing a polymer solution into a dispersion medium, which flows through a conduit and shears the dispersion medium. Liquid strands, streaks or droplets of the polymer solution are continuously shear-spun into elongated fibers. An inorganic precursor may be introduced with the polymer solution, resulting in fibers that include inorganic fibrils. The resulting composite inorganic/polymer fibers may be provided as an end product. Alternatively, the polymer may be removed to liberate the inorganic fibrils, which may be of the same or smaller cross-section as the polymer fibers and may be provided as an end product.Type: ApplicationFiled: May 16, 2012Publication date: January 10, 2013Inventors: ORLIN D. VELEV, STOYAN SMOUKOV, PETER GEISEN, MILES C. WRIGHT, SUMIT GANGWAL
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Patent number: 8349363Abstract: There is provided a new aqueous temperature responsive delivery system made with a temperature responsive polymer and a bioadhesive which is intrinsically cationic. This system may also have an effective amount of a treating agent, which may be a medical or cosmetic agent. The bioadhesive, temperature responsive delivery system is useful in delivering moisturizers or pharmaceutically active agents to the user in controlled release manners, through the tissues in a body cavity.Type: GrantFiled: November 7, 2008Date of Patent: January 8, 2013Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Yanbin Huang, Bashir Musse Sheikh-Ali, Jaeho Kim
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Publication number: 20130004558Abstract: The present invention relates to a molded article which is shaped of a polymer composition comprising 100 parts by weight of an olefin-based polymer, and 0.01 to 100 parts by weight of a C10-90 saturated chain hydrocarbon and/or liquid paraffin and 0.01 to 200 parts by weight of a releasable active compound per 100 parts by weight of said olefin-based polymer, and which is drawn at a draw ratio of 2 or more.Type: ApplicationFiled: December 25, 2009Publication date: January 3, 2013Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventor: Shizuto Yamakoshi
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Publication number: 20120329648Abstract: The present invention relates to methods for generating polymeric particles which comprise one or more active ingredients. The invention also relates to the use of such polymeric particles as a seed treatment. The present technology provides an improved seed treatment suitable for applying plant propagation materials. The seed treatment of the present technology includes the use of high aspect-ratio particles as a seed treatment. The present technology has been found to have advantageous properties associated with the seed treatment including increased adherence of the formulation to the seed and reduced tendency to dust off.Type: ApplicationFiled: November 12, 2010Publication date: December 27, 2012Applicant: SYNGENTA CROP PROTECTION LLCInventors: Jeffrey Fowler, Sejong Kim
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Publication number: 20120328677Abstract: An active agent composition includes particles containing a water-insoluble active agent or an active agent with a significant food effect; and a ternary amine polymer having both hydrophobic (meth)acrylate units and acid-soluble (meth)acrylate units, and an acidifying agent; wherein upon ingestion by a human subject, the acidifying agent facilitates the dissolution of the ternary amine polymer in the gastrointestinal tract.Type: ApplicationFiled: August 30, 2012Publication date: December 27, 2012Applicant: MUTUAL PHARMACEUTICAL COMPANY, INC.Inventors: Maher S. Kudsi, Rakeshkumar K. Lad, Hengsheng Feng
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Publication number: 20120321569Abstract: An adhesive composition is provided that is water-insoluble yet water-absorbent, i.e., capable of absorbing up to 15 wt. % water or more. The composition in composed of a film-forming hydrophilic polymer with at least one linear segment having a plurality of recurring polar groups along the polymer backbone, a complementary multifunctional polymer with a plurality of recurring functional groups that noncovalently bind to the polar groups on the film-forming polymer, and plasticizer. A method for manufacturing the adhesive composition is provided as well.Type: ApplicationFiled: August 24, 2012Publication date: December 20, 2012Applicants: CORIUM INTERNATIONAL, INC., A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCESInventors: Mikhail M. Feldstein, Danir F. Bairamov, Mikhail Borisovich Novikov, Valery G. Kulichikhin, Nicolai A. Platé, Gary W. Cleary, Parminder Singh
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Publication number: 20120322894Abstract: The present invention provides a tablet core which comprises at least about 95% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 95% by weight of an aliphatic amine polymer resin. The method comprises the step of compressing the aliphatic amine polymer to form the tablet core. The tablet core can further include one or more excipients.Type: ApplicationFiled: May 9, 2012Publication date: December 20, 2012Applicant: Genzyme CorporationInventors: Joseph Tyler, John S. Petersen
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Publication number: 20120316250Abstract: This invention provides a hard capsule that has excellent stability even when filled with a solvent for dissolving poorly soluble drugs, and that also achieves reduction in disintegration time, thereby ensuring excellent solubility. Specifically, the hard capsule of the present invention has a film comprising: (A) a polymer or copolymer obtained by polymerizing or copolymerizing, in the presence of polyvinyl alcohol and/or a derivative thereof, at least one polymerizable vinyl monomer represented by Formula (1): H2C?C(R1)—COOR2 ??(1) wherein R1 represents hydrogen or methyl, and R2 represents hydrogen or alkyl having 1 to 4 carbon atoms; and (B) native gellan gum.Type: ApplicationFiled: February 25, 2011Publication date: December 13, 2012Applicant: Nisshin Kasei Co., Ltd.Inventors: Toshiaki Moriuchi, Akane Kojo, Yusuke Hayashi, Hiroyuki Yoshino
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Publication number: 20120315306Abstract: A pharmaceutical composition including drug-containing nanoparticles having an average particle diameter of from 10 nm to 150 nm, the pharmaceutical composition being obtained by mixing water with a poorly water soluble drug-containing, water miscible solution that contains a poorly water soluble drug having a water solubility of 50 ?g/mL or less, a water soluble copolymer having a repeating unit represented by the following Formula (1), and a water miscible miscible solvent, wherein in Formula (1), n:m is within a range of from 0.25:0.75 to 0.95:0.05, R represents an alkyl group which may have a substituent, R1 and R2 each independently represent a hydrogen atom or a methyl group, and Me represents a methyl group; and a preparation for oral administration, which includes the pharmaceutical composition.Type: ApplicationFiled: January 27, 2011Publication date: December 13, 2012Applicant: FUJIFILM CORPORATIONInventor: Shigetomo Tsujihata
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Publication number: 20120308621Abstract: The present invention relates to a base formulation for cosmetic products, characterized in that it comprises, in percentage by weight of the formulation and according to the INCI nomenclature: a) from 0.2 to 10% of at least one hydroxylated ester; b) from 0.5 to 70% of a mixture of at least one mineral oil and at least one copolymer derived from alkenes; c) from 0.5 to 90% of at least one hydrogenated polymer; d) from 0.5 to 35% of a mixture of water and at least one glyceryl glucoside. Likewise, an object of this invention is a cosmetic product characterized in that it comprises the aforementioned base formulation, as well as the preparation procedure of the same.Type: ApplicationFiled: June 8, 2012Publication date: December 6, 2012Inventor: José Antonio NOVEJARQUE CONDE
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Publication number: 20120309761Abstract: A bicontinuous microemulsion of water, a monomer, and a surfactant copolymerizable with the monomer is polymerized to form a polymeric material, the polymeric material comprising a polymer matrix defining interconnected pores. The polymeric material may additional comprise at least one photochromic agent. The photochromic agent may be dispersed in one or both of the polymer matrix or the interconnected pores. The polymeric material may be used to form photochromic articles including ophthalmic articles such as contact lenses.Type: ApplicationFiled: October 27, 2010Publication date: December 6, 2012Applicant: Agency for Science, Technology and ResearchInventors: Edwin Pei Yong Chow, Jackie Y. Ying, Yuri Shona Pek
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Publication number: 20120309851Abstract: The present invention relates to methods for removing residual surface material from porous polymerized particle surfaces. The particles thus produced have an increase in surface porosity and uniformity in a variety of applications. Desirably, substantially the entire surface communicates with the interior of the particles. Also provided are the particles produced by such methods, further modifications of such particles, and methods for using the particles in a variety of applications. All described methods, compositions, and articles of manufacture are within the scope of the invention.Type: ApplicationFiled: May 4, 2010Publication date: December 6, 2012Inventors: Nai-Hong Li, Yuchiong Hsuanyu, James R. Benson, Marc Freed
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Patent number: 8324333Abstract: Materials and methods for the generation of polyelectrolyte multilayers that can erode to release cationic components. The multilayers comprise layers that contain one or more cations and one or more charge-dynamic anionic polymers. Charge-dynamic anionic polymers contain side chains having removable functional groups. Removal of the functional groups results in a change in the net change in the charge of the polymer which can disrupt interactions between cations and the anionic polymers and facilitate release of cations.Type: GrantFiled: June 5, 2009Date of Patent: December 4, 2012Assignee: Wisconsin Alumni Research FoundationInventors: Xianghui Liu, Jingtao Zhang, David M. Lynn
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Patent number: 8318797Abstract: Compositions for treating hair are disclosed. Methods of making and using compositions for treating hair are also disclosed.Type: GrantFiled: October 29, 2009Date of Patent: November 27, 2012Inventor: S. Katharine Presty
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Publication number: 20120288561Abstract: Methods and compositions for reducing the frequency of urination are disclosed. One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising an analgesic agent formulated in a delayed-release formulation. Another method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising multiple active ingredients. Yet another method comprises administering to a subject in need thereof an effective amount of a diuretic followed with another administration of an pharmaceutical composition comprising an analgesic agent.Type: ApplicationFiled: July 27, 2012Publication date: November 15, 2012Applicant: WELLESLEY PHARMACEUTICALS, LLCInventor: David A. Dill
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Publication number: 20120288462Abstract: A cosmetic preparation characterized by excellent adhesion at the place of application, comprises at least one silsesquioxane wax.Type: ApplicationFiled: February 2, 2011Publication date: November 15, 2012Applicant: SCHWAN-STABILO COSMETICS GMBH & CO. KGInventors: Simona Lebok, Sigrid Hell, Marika Skultety