Heterocyclic Monomer Patents (Class 514/772.5)
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Publication number: 20110130291Abstract: A process for treating foliage by retaining an active agent in contact with the foliage is provided that includes the application of a biologically active ingredient carrier granule. The granule includes a mineral component, a cellulosic component, and a binder flowing upon wetting intermixed with the mineral component and the cellulosic components. A biologically active ingredient is added to the granule to treat the foliage. The foliage in either a dry or pre-wetted state. The contact of the granule with water causes the granule to flow to form a coherent film bound by the binder on the foliage with the active agent retained in the film in contact with the foliage.Type: ApplicationFiled: November 30, 2010Publication date: June 2, 2011Applicant: The Andersons, Inc.Inventors: Timothy D. Birthisel, Joe Schumski, IV
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Publication number: 20110129510Abstract: The invention relates to a fibrous surface structure containing active ingredients with an adjustable active ingredient release profile, comprising a fibrous, polymeric, soluble and/or degradable active ingredient substrate and at least one active ingredient that is associated with the substrate and can be released by the fibrous surface structure; to formulations containing active ingredients, comprising such fibrous surface structures; to the use of fibrous surface structures containing active ingredients according to the invention for producing formulations containing active ingredients; and to a method for producing fibrous surface structures according to the invention.Type: ApplicationFiled: August 7, 2009Publication date: June 2, 2011Applicant: BASF SEInventors: Burghard Liebmann, Evgueni Klimov
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Patent number: 7947302Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: GrantFiled: December 15, 2008Date of Patent: May 24, 2011Assignee: Cordis CorporationInventors: Robert Falotico, Jonathon Z. Zhao
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Publication number: 20110117190Abstract: The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection moulding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form.Type: ApplicationFiled: November 7, 2008Publication date: May 19, 2011Inventors: Adrian Brown, Lee J. Gorringe, Stephen Mark McAllister, Wayne M. Matthews, Danielle Genevieve Rebecca Russell
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Publication number: 20110117142Abstract: The present invention relates to a polymeric composition for coating solid substrates (S) consisting of: a) 0.5-90% by weight of polyethylene glycol with a weight-average molecular weight in the range from 1500 to 20 000 g/mol (component A), b) 0.5-20% by weight of a water-soluble polyvinylpyrrolidone with a Fikentscher K value in the range from 12 to 90 (component B), c) 0-95% by weight of a solvent (L), and d) 0-70% by weight of one or more non-polymeric aids (component C).Type: ApplicationFiled: July 1, 2009Publication date: May 19, 2011Applicant: BASF SEInventors: Karl Kolter, Nils Rottmann, Maximilian Angel
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Publication number: 20110105615Abstract: The present invention relates to a tablet which is rapidly disintegrated in an oral cavity containing an active ingredient at a high content and a production method thereof. That is, the present invention provides a tablet which is rapidly disintegrated in an oral cavity containing an active ingredient in not less than 25% of the total weight, having a disintegration time of within 40 seconds and an absolute hardness of 1.8 N/mm2 or more, which is obtained by granulating a powder containing an active ingredient with a binding solution containing mannitol and corn-derived pregelatinized starch, mixing the resulting granules with at least one kind of a disintegrant selected from cornstarch, hydroxypropylstarch, carmellose and crospovidone, and compression molding the mixture.Type: ApplicationFiled: June 10, 2009Publication date: May 5, 2011Applicant: DAINIPPON SUMITOMO PHARMA CO., LTD.Inventors: Toru Fukushima, Takashi Shimizu, Teruko Yoshida
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Publication number: 20110104111Abstract: A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The at least one solvent may be selected from the group consisting of benzyl benzoate, decanol, ethyl hexyl lactate, and mixtures thereof and the at least one polymer may be selected from the group consisting of a polyester, pyrrolidone, ester of an unsaturated alcohol, ether of an unsaturated alcohol, polyoxyethylenepolyoxypropylene block copolymer, and mixtures thereof. In one embodiment, the at least one solvent is benzyl benzoate and the at least one polymer is polyvinylpyrrolidone. A stable, nonaqueous suspension formulation that includes the nonaqueous, single-phase vehicle and an active agent, and a method of forming the same, are also disclosed.Type: ApplicationFiled: November 1, 2010Publication date: May 5, 2011Inventors: Catherine M. Rohloff, Guohua Chen, Andrew S. Luk, Rupal A. Ayer, Paul R. Houston, Michael A. Desjardin, Pauline Zamora, Stan Lam
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Publication number: 20110091546Abstract: The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art. The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.Type: ApplicationFiled: October 20, 2010Publication date: April 21, 2011Applicant: FUJI CHEMICAL INDUSTRY CO., LTD.Inventors: Nobukazu TANAKA, Yoshiro Nagai, Hiroshi Kawaguchi, Tadashi Fukami, Terumasa Hosokawa
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Publication number: 20110081415Abstract: A sugar-coated agent that includes a core, a film layer that mainly includes a film component, the outer surface of the core being coated with the film layer, a sugar coating layer that mainly includes a sugar coating component, the outside of the film layer being coated with the sugar coating layer, and a middle layer that includes a film component and a sugar coating component and is provided between the film layer and the sugar coating layer, wherein within the middle layer, the concentration of the sugar coating component at the interface between the middle layer and the sugar coating layer is higher than the concentration of the sugar coating component at the interface between the middle layer and the film layer.Type: ApplicationFiled: November 4, 2010Publication date: April 7, 2011Applicant: TAISHO PHARMACEUTICAL CO., LTDInventors: Junichi Kishimoto, Reiko Tanaka
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Publication number: 20110076250Abstract: A biodegradable microfiber absorbent comprises a substantially homogeneous mixture of at least one hydrophilic polymer and at least one biodegradable polymer. The absorbent can be prepared by an electro hydrodynamic spinning of a substantially homogeneous polymer mixture. Medical dressings for burns and wounds, cavity dressings, drug delivery patches, face masks, implants, drug carriers that comprises at least one microfiber electrospun from a polymer mixture are provided. The dressings can have variable water vapor penetration characteristics and variable biodegradation times.Type: ApplicationFiled: December 7, 2010Publication date: March 31, 2011Inventors: Bronislava G. Belenkaya, Vyacheslav N. Polevov, Valentina I. Sakharova, Claudia Polevov
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Publication number: 20110046606Abstract: Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.Type: ApplicationFiled: October 18, 2010Publication date: February 24, 2011Inventors: Guohua Chen, Paul R. Houston, Lothar Kleiner, John J. Spaltro
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Publication number: 20110046072Abstract: The invention relates to a solid pharmaceutical preparation with delayed release of the active ingredients which is suitable in particular for use in animals.Type: ApplicationFiled: April 23, 2009Publication date: February 24, 2011Applicant: BAYER ANIMAL HEALTH GMBHInventors: Venkata-Rangarao Kanikanti, Thomas Bach, Michael Traeubel, Gertraut Altreuther, Martina Rehagen, Axel Schmidt
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Publication number: 20110045029Abstract: A composition for oral delivery of a poorly absorbed drug is disclosed. The composition includes the drug, an enhancer for increasing absorption of the drug through the intestinal mucosa, a promoter, which further increases the absorption of the drug in the presence of the enhancer, and optionally a protector for protecting the drug from physical or chemical decomposition or inactivation in the gastrointestinal tract. Illustrative enhancers include sucrose fatty acid esters, and illustrative promoters include aminosugars and amino acid derivatives, such as poly(amino acids). Illustrative protectors include methylcellulose, poly(vinyl alcohol), and poly(vinyl pyrrolidone).Type: ApplicationFiled: February 23, 2010Publication date: February 24, 2011Applicant: ProCarrier, Inc.Inventors: Seung-Ho Choi, Seong-Wan Cho
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Publication number: 20110013476Abstract: The invention concerns a process for the production of a tableting excipient with the following process steps: At least two of the following components are made available: A filler/binding agent; A lubricant; A flow regulating agent; A disintegrant; The available components are mixed together.Type: ApplicationFiled: March 13, 2009Publication date: January 20, 2011Applicant: J. RETTENMAIER & SOHNE GMBH & CO. KGInventors: Edmont Stoyanov, Reinhard Vollmer, Tobias Götz
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Publication number: 20110015280Abstract: The present invention relates to an ampholytic copolymer, to a process for its preparation, to cosmetic or pharmaceutical compositions which comprise at least one such ampholytic copolymer, and to further uses of these copolymers.Type: ApplicationFiled: July 21, 2006Publication date: January 20, 2011Applicant: BASF AKTIENGESELLSCHAFTInventors: Son Nguyen Kim, Ivette Garcia Castro, Klemens Mathauer
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Publication number: 20110008424Abstract: Disclosed are a sustained release solid formulation comprising a drug, for example, oxycodone or its pharmaceutically acceptable salt, in a water-insoluble matrix, which comprises a wax type excipient and copovidone, and thus, has increased compressibility and fluidity and reduced adhesiveness, and a method of preparing the same.Type: ApplicationFiled: April 28, 2008Publication date: January 13, 2011Applicant: HANA PHARM. CO., LTD.Inventors: Shajoung Chang, Oak Choi
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Patent number: 7863388Abstract: Water-soluble functionalized cationic copolymers obtainable by a process which comprises reacting a cationic base polymer which contains amino groups with at least one functional compound reactive to at least a part of the amino groups on the base polymer, are useful in personal care and cosmetic formulations.Type: GrantFiled: November 9, 2006Date of Patent: January 4, 2011Assignee: BASF SEInventors: Zhiqiang Song, John Jennings, Jianwen Mao
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Publication number: 20100278764Abstract: Disclosed herein is a cosmetic and/or pharmaceutical composition comprising, in a physiologically acceptable medium, at least one (co)polymer comprising a polymer backbone and at least one junction group linked to the polymer backbone and capable of establishing H bonds with at least one partner junction group, each pairing of a junction group involving at least 3H bonds, wherein the at least one (co)polymer comprises at least one ionizable group. Also disclosed herein is a cosmetic treatment process comprising applying the composition to keratin materials.Type: ApplicationFiled: July 9, 2010Publication date: November 4, 2010Inventors: Nathalie Mougin, Sandrine Chodorowski-kimmes, Xavier Schultze
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Publication number: 20100278763Abstract: Polymers are described comprising a) one or more of the recurring structural units of the formula (1) where R1 is hydrogen, methyl or ethyl and A is C1-C8 alkylene, and Q+ is H+, NH4+, Li+, Na+, K+, ½Ca++, ½ Mg++, ½ Zn++ or ? Al+++, and the neutralization degree of the structural units of formula (1) is 50 to 100 mol-%, and b) one or more of the recurring structural units of the formula (2) where R1 and A are R1 and A from formula (1) and X+ is [HNR5R6R7]+, where R5, R6 and R7 can independently from each other be hydrogen, a linear or branched alkyl group with 1 to 22 carbon atoms, a linear or branched, simple or polyunsaturated alkenylene group with 2 to 22 carbon atoms, a C6-C22-alkylamidopropyl group, a linear monohydroxyalkyl group with 2 to 10 carbon atoms or a linear or branched dihydroxyalkyl group with 3 to 10 carbon atoms, and wherein at least one of the groups R5, R6 and R7 is not hydrogen, with the proviso that the molar ratio of the structural units of formula (1), where Q+ is NH4+, Li+, NType: ApplicationFiled: December 16, 2008Publication date: November 4, 2010Applicant: CLARIANT FINANCE (BVI) LIMITEDInventors: Matthias Loeffler, Thomas Lindner, Ute Back, Michael Hornung
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Publication number: 20100240773Abstract: The present invention relates generally to multifunctional polymeric linkers capable of linking a plurality of biologically active compounds. More particularly, the invention relates to the use of such multifunctional linkers that can effectively present two or more ligands simultaneously to two or more biological targets.Type: ApplicationFiled: March 23, 2010Publication date: September 23, 2010Inventors: Kenneth Korzekwa, Mark J. Rosen
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Publication number: 20100209361Abstract: The present invention relates to a copolymer with high cationic charge based on quaternized nitrogen-containing monomers, to cosmetic or pharmaceutical compositions which comprise at least one such copolymer, and to further uses of these copolymers.Type: ApplicationFiled: July 1, 2008Publication date: August 19, 2010Applicant: BASF SEInventors: Nicole Meier, Ivette Garcia Castro, Claudia Wood, Jessica Staub
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Patent number: 7759400Abstract: It is intended to provide a composition which has well-balanced pressure-sensitive adhesiveness and cohesive force as well as favorable application properties to the skin, and a patch which has the above-described characteristics and hardly peels off. This object can be achieved by providing a composition comprising an acrylic copolymer containing from 3 to 25% by weight of hydroxyethyl (meth)acrylate as a constituent, a plasticizer and a pseudo-crosslinking compound, wherein the ratio of the content of the plasticizer to the content of the pseudo-crosslinking compound ranges from 30:1 to 250:1, and a patch.Type: GrantFiled: January 7, 2005Date of Patent: July 20, 2010Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventor: Minoru Kohara
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Publication number: 20100137455Abstract: Copolymers for use in solubilizing substances which are insoluble in water, substances which are only sparingly soluble in water, and combinations thereof; such copolymers comprising: (a) 60 to 99% by weight of N-vinylcaprolactam; and (b) 1 to 40% by weight of at least one other monomer selected from the group consisting of: C8-C30-alkyl esters of monoethylenically unsaturated C3-C8-carboxylic acids; N—C8-30 alkyl-substituted amides and N,N—C8-30 dialkyl-substituted amides of acrylic acid, methacrylic acid, or combinations thereof; vinyl esters of aliphatic unbranched C8-C30-carboxylic acids; C8-C30-alkyl vinyl ethers; and mixtures thereof.Type: ApplicationFiled: August 2, 2006Publication date: June 3, 2010Applicant: BASF SEInventors: Nathalie Bouillo, Marianna Pierobon, Gerhard Rossler, Rainer Dobrawa, Kathrin Meyer- Boehm, Ronald Frans-Maria Lange
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Publication number: 20100112050Abstract: Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, particularly anti-migraine agents to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract.Type: ApplicationFiled: October 29, 2009Publication date: May 6, 2010Inventors: Je Phil Ryoo, Chun Kwong Chu, Zheng Wang
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Publication number: 20100113588Abstract: Compositions for treating hair are disclosed. Methods of making and using compositions for treating hair are also disclosed.Type: ApplicationFiled: October 29, 2009Publication date: May 6, 2010Inventor: S. Katharine Presty
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Publication number: 20100112015Abstract: With an object of providing an orally administered agent (in particular a film-shaped orally administered agent) with which the ease and safety of taking the agent are improved, to attain this object, in an orally administered agent 1b having one drug-containing layer 11 and two water-swellable gel-forming layers 12, the water-swellable gel-forming layers 12 are provided, either directly or via intermediate layers, on the both faces of the drug-containing layer 11.Type: ApplicationFiled: November 30, 2009Publication date: May 6, 2010Applicant: LINTEC CORPORATIONInventor: Eiji Nogami
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Publication number: 20100104647Abstract: The invention provides a process for making hollow microparticles. The process comprises providing a dispersion having a continuous aqueous phase and a discontinuous organic phase and polymerising a monomer in the dispersion to form hollow polymeric microparticles. The continuous aqueous phase of the dispersion comprises a stabiliser and the discontinuous organic phase of the dispersion comprises the monomer and an organic liquid. The monomer has two or more polymerisable groups per molecule. Prior to the step of polymerising the monomer, the discontinuous organic phase does not contain a polymer.Type: ApplicationFiled: February 8, 2008Publication date: April 29, 2010Applicant: NewSouth Innovations Pty LimitedInventor: Seet Rui Simon TING
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Publication number: 20100104656Abstract: A low melting binder composition for preparation of pharmaceutical tablets and/or granules which comprises a polymer and a hydrophobic meltable binder.Type: ApplicationFiled: March 19, 2008Publication date: April 29, 2010Inventors: Paul Wan Sia Heng, Wai See Cheong, Zhi Hui Loh, Dipan B. Ray, Rama Haldar, Yolande Anthony
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Publication number: 20100098649Abstract: The present invention relates to the field of perfumery. More particularly, it concerns co-polymers, derived from a maleic anhydride derivative and a ethylenic derivative, comprising at least one ?-oxy or ?-thio carbonyl moiety capable of liberating an active molecule such as, for example, an ?,?-unsaturated ketone, aldehyde or carboxylic ester. The present invention concerns also the use of polymers or co-polymers in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's compounds.Type: ApplicationFiled: October 5, 2007Publication date: April 22, 2010Inventors: Damien Berthier, Andreas Herrmann
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Publication number: 20100092545Abstract: The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.Type: ApplicationFiled: November 9, 2009Publication date: April 15, 2010Applicant: MonoSol RX, LLCInventors: Robert K. Yang, Richard C. Fuisz, Garry L. Myers, Joseph M. Fuisz
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Publication number: 20100092525Abstract: A medical device for delivery of a therapeutic agent to a physiological target site includes a flexible receptacle containing said therapeutic agent, wherein at least a part of the receptacle is formed of a water-soluble or water-dispersible material. The therapeutic agent may include a haemostatic agent and the physiological target site may be a wound.Type: ApplicationFiled: November 16, 2007Publication date: April 15, 2010Applicant: MEDTRADE PRODUCTS LIMITEDInventors: Craig Julian Hardy, Stewart Andrew Darby, Andrew Guy Eason
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Publication number: 20100087548Abstract: The present invention relates to a method of formulating a liquid dual phase cosmetic or pharmaceutical composition in which the phases are separate before and after being mixed, the method comprising combining an aqueous phase and an oil phase, wherein one of the aqueous and oil phases has incorporated therein, as a demixing agent, an effective amount of a non-cationic film forming agent such as polyvinylpyrrolidone and copolymers thereof. The compositions of the invention are particularly useful as makeup removers.Type: ApplicationFiled: December 8, 2009Publication date: April 8, 2010Inventors: Linda Najdek, Derron T. Peck, Elena M. Ciriello, Ralph Vitale
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Publication number: 20100086514Abstract: A contact lens care solution comprising: a cationic antimicrobial component having an average molecular weight (MNA), and a cationic oligomer or nitrogen/amine oligomer having a number average molecular weight (MNO) from 500 daltons to 15,000 daltons. The lens care solutions are used to clean and disinfect contact lenses, and in particular, soft, silicone hydrogel contact lenses.Type: ApplicationFiled: October 1, 2009Publication date: April 8, 2010Inventors: X. Michael Liu, David J. Heiler
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Publication number: 20100075849Abstract: The present invention comprises formulations comprising at least one pesticide and at least one co-polymer comprising a) 1-vinyl-2-pyrrolidinone as comonomer a); and b) 60-99 wt % at least one comonomer b) chosen from the group of laurylacrylate and vinyl ester of neodecanoic acid in polymerized form, methods of combating harmful insects and/or phytopathogenic fungi, a method of controlling undesired vegetation and methods of improving the health of plants based on the afore-mentioned formulations.Type: ApplicationFiled: November 9, 2007Publication date: March 25, 2010Applicant: BASF SEInventors: Yvonne Dieckmann, Michael Ishaque, Ingo Münster, Laurent Picard, Wolfgang Kerl, Jürgen Langewald, Klaus Kreuz, Harald Köhle, Felix Christian Görth
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Publication number: 20100075850Abstract: The present invention comprises formulations comprising at least one pesticide and at least one co-polymer comprising (a) a N-vinylamid comonomer a) of formula (I) wherein R1 and R2 are independently of one another hydrogen or C1-C4 alkyl, preferably hydrogen or R1 and R2 represent together a —(CH2)x mojety, which forms together with the nitrogen and the carbonyl-moiety a 5-8 membered ring, and (b) at least one comonomer b) selected from the group consisting of vinylpyrridin, vinylpyrridin derivatives and N-vinlyimidazole in polymerized form, methods of combating harmful insects and/or phytopathogenic fungi, a method of controlling undesired vegetation and methods of improving the health of plants based on the afore-mentioned formulations.Type: ApplicationFiled: November 9, 2007Publication date: March 25, 2010Inventors: Yvonne Dieckmann, Michael Ishaque, Ingo Münster, Laurent Picard, Wolfgang Kerl, Jürgen Langewald, Klaus Kreuz, Harald Köhle, Felix Christian Görth
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Publication number: 20100068268Abstract: The invention provides starch-based microparticles with high loading capacity for the stabilization and/or controlled release of one or more agents, for example, a pharmaceutical, a taste masking agent, a flavoring agent, or a combination thereof, disposed within the microparticles, and to methods of making and using such microparticles.Type: ApplicationFiled: September 15, 2009Publication date: March 18, 2010Inventors: Miloud Rahmouni, Mohamed Nabil Khalid, Vinayak Sant, Abdelaziz Tafer, Damon Smith
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Publication number: 20100063167Abstract: The present invention comprises the use of formulations comprising at least one pesticide and at least one co-polymer comprising (a) at least one comonomer (a) selected from the group consisting of olefins, vinylethers, vinyl pyrrolidone and styrene; and (b) at least one comonomer (b) selected from the group consisting of ethylenically unsaturated dicarboxylic mono and diesters, wherein the alcohol moiety of the mono- or diester has the structure of formula I wherein R1 is 1,2-propylene or 2,3 propylene R2 is ethylene; R3 is hydrogen, branched or linear C1-C40, preferably C1-C24 alkyl, phenyl, phenyl substituted with C1-C20 alkyl, benzyl, benzyl substituted with C1-C20 alkyl; n corresponds to a value from 0 to 140, preferably 0-50, more preferably 0-20. p corresponds to a value from 0 to 100 wherein the sum of n and p is at least 1, preferably 1-60, most preferably 5-40.Type: ApplicationFiled: November 9, 2007Publication date: March 11, 2010Applicant: BASF SEInventors: Yvonne Dieckmann, Michael Ishaque, Ingo Münster, Laurent Picard, Wolfgang Kerl, Jürgen Langewald, Klaus Kreuz, Harald Köhle, Felix Christian
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Publication number: 20100056647Abstract: The present invention relates to aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers. Also disclosed are methods for the rheological modification of aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers.Type: ApplicationFiled: August 27, 2009Publication date: March 4, 2010Applicant: Ciba CorporationInventors: Keith Graham, David Normington, Howard R. Dungworth, John M. Plonka
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Publication number: 20100047337Abstract: According to the invention glyceryl monostearate and a polymeric binder are employed as a spheronising aid in the manufacture of pharmaceutical spheroids containing no or substantially no microcrystalline cellulose. The spheroids can contain one or more therapeutically active agent which undergoes no or substantially no degradation when stored under accelerated temperature and humidity conditions. A coating may be applied to the spheroids; when present, the coating is preferably a controlled release coating.Type: ApplicationFiled: March 16, 2007Publication date: February 25, 2010Applicant: EURO-CELTIQUE S.A.Inventors: Malcolm Walden, Hassan Mohammad, Geoffrey Gerard Hayes, Helen Kathleen Danagher, Jonathan Oliver Whitehouse
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Publication number: 20100048737Abstract: The present invention relates to cosmetic or dermatological formulations comprising at least one active compound, at least one polymer which is molecularly imprinted in the presence of this active compound and at least one fatty phase.Type: ApplicationFiled: September 14, 2007Publication date: February 25, 2010Applicant: BASF SEInventors: Volker Wendel, Oliver Brüggemann, Arne Ptock
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Patent number: 7662864Abstract: Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from the controlled release of an agent(s) over a period of time. The polymers are prepared by a process involving various alternative and sequential steps that allow the design a priori of products with specific characteristics. The polymers are suitable as delivery systems, either by themselves, as compositions, formulations or devices.Type: GrantFiled: June 4, 2004Date of Patent: February 16, 2010Assignee: Rutgers, The State University of New JerseyInventors: Suseela Kanamathareddy, Stephen Goodrich, Yun Choe
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Publication number: 20100028452Abstract: A delivery system for inclusion in an edible composition is formulated to have at least one active component encapsulated within an encapsulating material, whereby the delivery system has a tensile strength suitable for delivering the active component at a desired release rate.Type: ApplicationFiled: October 13, 2009Publication date: February 4, 2010Applicant: Cadbury Adams USA LLCInventors: Navroz BOGHANI, Petros Gebreselassie
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Publication number: 20100021544Abstract: The invention relates to a method for preparing a cross-linked sterile and homogeneous hydrogel for injection, characterized in that it comprises the following steps: (a) preparing an aqueous solution containing a polymer derived from cellulose and at least one water-soluble polymer, the total polymer content ranging from 0.5 and 5 wt %, preferably from 1 to 4 wt % and more preferably from 1.5 to 3 wt %; (b) optionally adding sold particles; (c) pouring the resulting liquid mixture with the optional solid particles into a vessel and closing dais vessel using a water-tight and gas-tight system; and (d) exposing said vessel containing the liquid and the optional solid particles to a radiation dose of between 5 and 50 kGy, preferably between 20 and 30 kGy, and more preferably of about 25 kGy. The invention also relates to a hydrogel obtained according to the above method and to the use thereof in medical applications.Type: ApplicationFiled: November 16, 2007Publication date: January 28, 2010Applicant: BIOMATLANTEInventors: Xavier Bourges, Serge Baroth
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Publication number: 20100009004Abstract: The present invention provides an intraorally rapidly disintegrating tablet that can be formed using an ordinary apparatus, that has hardness with no practical problem and that disintegrates rapidly with good feeling in the oral cavity. The present invention is intraorally rapidly disintegrating tablet produced by compression molding of a granule coated with a disintegrant, in which the granule contains a disintegrant also inside thereof and a drug except ambroxol hydrochloride inside and/or outside thereof.Type: ApplicationFiled: September 18, 2009Publication date: January 14, 2010Applicant: TEIJIN PHARMA LIMITEDInventors: Tomoya AKUTAGAWA, Masahiko Narasaki
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Publication number: 20100009011Abstract: The invention relates to polyurethane foams comprising polymers of heterocyclic N-vinyl monomers (i) and a disinfectant or bleaching agent (ii).Type: ApplicationFiled: June 18, 2007Publication date: January 14, 2010Applicant: BASF SEInventors: Andreas Arlt, Michael Klemm, Bernhard Fussnegger, Rudi Mortelmans, Peter Spanhove
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Publication number: 20100004345Abstract: The invention generally relates to film coating compositions and processes for film coating pharmaceutical, nutraceutical, and food products. One film coating composition includes a shellac in an aqueous solution; a hydrolyzed starch product; an optional plasticizer; and a coating resin. The coating resin may be one or more of polyvinyl pyrrolidone, polyvinyl alcohol, and poly(vinyl pyrrolidone-vinyl acetate). The shellac, hydrolyzed starch product, plasticizer and coating resin comprise the solids in the composition.Type: ApplicationFiled: June 30, 2009Publication date: January 7, 2010Inventors: Charles A. Signorino, Terry L. Smith, Stephen Levine
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Publication number: 20100003338Abstract: Embodiments include a vehicle for delivery of nitric oxide comprising: a collection of micelles having an internal micelle core that comprises a polymer with N-diazeniumdiolate comprising NO complexed with secondary amines of the polymer. Embodiments include a method of making a nitric oxide vehicle comprising dissolving a polymer that comprises secondary amines in an aqueous solution and combining the polymer with nitric oxide in the solution to form a N-diazeniumdiolate comprising the nitric oxide complexed with the secondary amines, with the formation of the N-diazeniumdiolate causing the polymer to be at least partially insoluble in the solution and to form a collection of micelles that have an internal core that comprises N-diazeniumdiolate.Type: ApplicationFiled: July 3, 2008Publication date: January 7, 2010Inventors: Jeffrey A. Hubbell, Yun Suk Jo, Andre J. Van der Vlies
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Publication number: 20090324710Abstract: Provided are prophylactic and therapeutic methods of treatment of subjects for the purpose of inhibiting vaso-occlusive events, including embolism, by administering agents, including anagrelide and anagrelide derivatives, which reduce the number of circulating platelets to low normal or to below normal levels. Methods and pharmaceutical preparations comprising such agents are provided.Type: ApplicationFiled: June 16, 2009Publication date: December 31, 2009Inventors: Paul F. Glidden, Alison J. Pilgrim, Stephen R. Hanson
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Publication number: 20090318568Abstract: An adherent coating composition is described having a reservoir of medication or other substance and capable of intimate contact with a target area of exposed tissue, rapid conveyance of the medication onto or into the target area. Mixtures of polyvinylpyrrolidone and glycerin have been found to dissolve a large number of medications while producing an adherent film. Application of the present composition to provide anti-cancer medication to exposed tissue resulting from tumor resection is also described.Type: ApplicationFiled: August 26, 2009Publication date: December 24, 2009Inventor: Ray L. Hauser
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Publication number: 20090312441Abstract: A solid pharmaceutical composition comprising a poorly water soluble drug, a polymer which is solid at room temperature, and a disintegrant in an amount of less than 10% by weight, wherein the amounts by weight are based on the total weight of the composition.Type: ApplicationFiled: December 20, 2005Publication date: December 17, 2009Applicant: NOVARTIS AGInventors: Michael Ambühl, Dieter Becker, Olivier Lambert, Barbara Lückel